Benign neoplasm: Bladder

CD2_BENIGN_BLADDER

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D30.3&
  • Hospital discharge: ICD-9 2233
  • Hospital discharge: ICD-8 2233
  • Cause of death: ICD-10 D30.3&
  • Cause of death: ICD-9 2233
  • Cause of death: ICD-8 2233

2 out of 7 registries used, show all original rules.

390

4. Check minimum number of events

None

390

5. Include endpoints

None

390

6. Filter based on genotype QC (FinnGen only)

348

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D30
Name in latin
Neoplasma benignum vesicae urinariae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2475 947 1483
Only index persons 1772 757 1015
Unadjusted period prevalence (%)
Whole population 0.04 0.03 0.04
Only index persons 0.03 0.03 0.04
Median age at first event (years)
Whole population 63.13 60.11 64.96
Only index persons 61.04 57.95 63.34

-FinnGen-

Key figures

All Female Male
Number of individuals 348 124 224
Unadjusted period prevalence (%) 0.08 0.04 0.10
Median age at first event (years) 63.08 56.21 66.88

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
355
Matched controls
3546
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D30.3
ICD-10 Finland
Benign neoplasm: Bladder
+∞
307.7
296
*
KCD02
NOMESCO Finland
Transurethral resection of bladder
39.9
209.0
140
57
UKC02
NOMESCO Finland
Cystoscopy
20.2
174.0
273
502
D41.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bladder
37.3
160.4
106
40
KCD32
NOMESCO Finland
Cystoscopic destruction of tumour of bladder
60.7
91.9
52
10
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
20.6
89.9
73
44
C67.9
ICD-10 Finland
Malignant neoplasm: Bladder, unspecified
17.2
65.3
57
39
KCD05
NOMESCO Finland
Excision of bladder lesion during urinary tract endoscopy with photodynamic diagnosis (PDD)
20.9
62.2
49
27
R31
ICD-10 Finland
Unspecified haematuria
6.4
61.5
139
322
8120/3-C67.9
ICD-O-3
Transitional cell carcinoma, NOS, of bladder, NOS
17.7
60.9
52
34
C67.2
ICD-10 Finland
Malignant neoplasm: Lateral wall of bladder
21.0
58.7
46
25
UKC05
NOMESCO Finland
Cystoscopy and bladder biopsy
24.3
58.6
43
20
2233A
ICD-9 Finland
Benign neoplasm of kidney and other urinary organs, Bladder
+∞
39.3
37
*
22330
ICD-8 Finland
Benign neoplasm of kidney and other urinary organs, Bladder
+∞
29.6
28
*
1530
FHL
Urethrocystoscopy
9.1
28.7
37
45
7323
FHL
Electrosection of TU bladder wall change
101.0
26.0
28
*
D30.0
ICD-10 Finland
Benign neoplasm: Kidney
41.5
22.0
27
7
8120/1-C67.9
ICD-O-3
Urothelial papilloma, NOS, of bladder, NOS
188.8
17.7
18
*
7321
FHL
TU biopsy, coagulation or laser
40.0
15.5
19
5
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.8
15.4
51
149
WX320
NOMESCO Finland
Spinalanesthesy
2.6
14.9
123
608
KCB00
NOMESCO Finland
Biopsy of bladder
44.4
14.2
17
*
8130/1-C67.9
ICD-O-3
Papillary urothelial neoplasm of low malignant potential of bladder, NOS
41.7
13.3
16
*
J01EA01
ATC
trimethoprim; systemic
2.3
11.5
114
600
JN3AD
NOMESCO Finland
Abdominal CT examination
2.7
11.1
67
279
C67.1
ICD-10 Finland
Malignant neoplasm: Dome of bladder
61.8
10.7
12
*
J01MA02
ATC
ciprofloxacin; systemic
2.1
10.0
172
1113
KCW96
NOMESCO Finland
Other operations on bladder
20.7
9.9
14
7
C67.4
ICD-10 Finland
Malignant neoplasm: Posterior wall of bladder
56.5
9.7
11
*
1888X
ICD-9 Finland
Malignant neoplasm of bladder, Other specified sites of bladder
37.7
9.1
11
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
8.5
104
587
TKC20
NOMESCO Finland
Catheterisation of bladder
2.8
8.3
45
177
ZXE00
NOMESCO Finland
One hour or less
1.9
7.9
146
948
KCW02
NOMESCO Finland
Lavation of bladder for coagulated blood
7.2
7.9
18
26
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
4.0
7.8
22
57
18899
ICD-8 Finland
Malignant neoplasm of bladder
46.0
7.7
9
*
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.1
7.5
80
426
R33
ICD-10 Finland
Retention of urine
2.4
7.5
58
271
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.2
7.5
72
369
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.2
7.2
66
331
8130/2-C67.9
ICD-O-3
Papillary urothelial carcinoma, non-invasive of bladder, NOS
9.0
7.1
14
16
C67.0
ICD-10 Finland
Malignant neoplasm: Trigone of bladder
10.3
7.1
13
13
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
7.0
118
737
C67
ICD-10 Finland
Malignant neoplasm of bladder
17.1
6.8
10
6
KH1CD
NOMESCO Finland
Very extensive urinary tract ultrasound examination
7.4
6.8
15
21
N39.3
ICD-10 Finland
Stress incontinence
3.1
6.7
28
95
XKD00
NOMESCO Finland
Uroflowmetry
1.9
6.3
89
524
UJF32
NOMESCO Finland
Coloscopy
1.9
6.3
107
669
J01DB01
ATC
cefalexin; oral
2.0
6.1
282
2353
ZX136
NOMESCO Finland
Intravesicalis
8.8
6.1
12
14

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
118
168
10.01
84.27
4.0
2.9
—
—
—
0
0
89
386
2.74
13.89
1.4
1.4
—
—
—
0
0
162
989
2.17
11.37
5.0
3.4
—
—
—
0
0
168
1068
2.08
10.34
7.5
3.7
95.05
112.81
e6/l
0.09
138
831
129
765
2.08
9.37
4.9
2.9
3.49
4.28
e6/l
0.55
121
700
63
277
2.55
9.33
3.7
2.7
0.33
0.62
e6/l
0.43
63
266
169
1122
1.96
8.80
2.7
2.3
—
—
—
0
0
144
916
1.96
8.40
7.5
3.6
0.24
0.51
e6/l
1.50
115
689
213
1551
1.93
8.21
6.0
4.3
54.90
4.80
estimate
0.69
49
339
214
1569
1.91
7.99
6.1
4.3
0.00
0.98
estimate
0.51
44
310
209
1531
1.88
7.71
6.1
4.3
0.00
0.00
estimate
-0.00
47
329
254
1987
1.97
7.62
9.6
5.0
3328.17
462.74
e6/l
—
6
35
171
1182
1.86
7.52
8.5
4.3
69.90
102.61
e6/l
0.65
143
862
174
1222
1.83
7.17
5.2
3.8
6.15
6.20
ph
0.24
98
661
90
533
1.92
6.21
7.5
3.3
2.96
1.84
e6/l
0.37
57
279
132
904
1.73
5.57
2.6
2.2
2.75
3.03
mg/l
0.80
114
776
103
661
1.78
5.43
5.3
3.4
553.36
549.70
mosm/kgh2o
0.06
97
580
55
288
2.07
5.33
2.1
3.1
65.27
66.12
g/l
0.34
50
263
62
342
1.98
5.21
2.0
2.5
64.17
68.69
e9/l
0.68
48
267
182
1383
1.65
5.04
3.4
2.8
—
—
estimate
—
0
0
205
1611
1.64
4.92
8.9
7.4
1.20
1.21
mmol/l
1.01
175
1383
175
1324
1.63
4.88
3.8
3.0
134.36
146.91
ug/l
0.31
165
1224
51
270
2.04
4.79
3.7
2.4
0.00
0.05
estimate
—
9
56
10
14
7.31
4.68
1.8
1.9
12.50
15.86
%
—
10
14
119
824
1.67
4.67
5.0
3.9
0.00
0.11
estimate
0.58
35
255
73
445
1.80
4.50
2.1
2.4
1.64
1.77
%
0.74
61
401
63
368
1.86
4.45
2.1
1.6
—
—
—
0
0
7
6
11.85
4.29
1.1
1.7
28.71
34.33
%
—
7
6
154
1157
1.58
4.25
5.9
4.3
0.00
0.04
estimate
1.32
41
275
15
47
3.28
4.09
1.3
1.3
—
—
—
0
0
195
1566
1.54
3.89
21.2
16.5
1.35
1.33
inr
0.22
179
1313
182
1458
1.51
3.56
7.6
6.7
1.20
1.21
mmol/l
0.67
167
1332
47
270
1.85
3.49
1.6
1.4
—
—
—
0
0
31
154
2.11
3.46
3.5
2.5
0.13
0.02
estimate
—
8
47
199
1635
1.49
3.37
8.8
7.0
11.12
12.30
umol/l
1.57
194
1559
42
237
1.87
3.30
2.1
3.0
—
—
—
0
0
53
324
1.75
3.22
4.7
4.1
7.29
7.36
ph
0.48
35
226
9
20
4.58
3.13
1.4
1.8
42.23
35.62
%
—
9
20
118
888
1.49
3.02
5.8
4.3
0.00
0.01
estimate
0.50
42
297
200
1673
1.44
2.92
12.2
9.6
4.22
4.36
e9/l
0.37
177
1432
49
302
1.72
2.89
2.4
2.3
170.00
138.07
ug/g
0.16
43
245
139
1090
1.45
2.85
3.7
3.4
7.15
7.59
mmol/l
0.65
118
899
23
111
2.14
2.79
2.2
4.7
1.40
3.72
ratio
1.69
16
65
136
1066
1.44
2.79
3.8
3.4
41.30
61.92
mg/l
1.15
90
719
214
1826
1.43
2.72
6.6
5.2
6.93
6.79
mmol/l
0.46
208
1739
95
699
1.49
2.68
5.5
4.0
—
0.40
—
0
10
138
1095
1.42
2.61
5.2
4.1
7.55
10.49
mg/mmol
0.79
90
703
173
1429
1.41
2.60
6.7
5.2
34.10
34.90
g/l
1.05
165
1348
54
352
1.63
2.59
1.5
1.3
560.00
437.18
titre
0.25
16
85
5
7
7.22
2.55
1.6
1.0
—
—
—
0
0
95
708
1.46
2.50
1.8
1.8
385.82
9794253.56
pmol/l
0.50
77
582
92
684
1.46
2.44
5.7
4.4
1.02
1.02
kg/l
0.08
71
445
61
416
1.56
2.43
6.8
7.3
0.39
0.91
mmol/l
0.62
49
349
55
367
1.59
2.41
1.3
1.3
—
—
—
0
0
167
1388
1.38
2.35
8.9
6.1
58.48
58.94
%
0.20
162
1314
61
420
1.54
2.34
6.8
7.3
7.42
7.41
ph
0.54
36
251
52
346
1.59
2.31
5.4
3.7
7.38
7.38
ph
0.01
33
202
8
23
3.53
2.28
1.3
1.4
—
—
—
0
0
8
23
3.53
2.28
1.5
1.3
—
—
—
0
0
141
1147
1.38
2.23
4.1
3.4
1833.40
1671.95
ng/l
0.21
123
996
24
129
1.92
2.22
3.0
2.0
—
—
—
0
0
172
1447
1.36
2.20
2.9
2.3
95.45
94.77
pmol/l
0.07
89
784
86
646
1.44
2.15
1.7
1.8
1043.42
1163.77
nmol/l
0.67
65
495
51
346
1.55
2.09
1.5
1.6
—
—
—
0
0
106
831
1.39
2.08
3.5
3.1
377.04
357.59
umol/l
0.92
89
711
22
118
1.92
2.06
3.9
3.3
405.33
298.45
mg/l
—
9
44
121
972
1.37
2.04
3.4
2.6
54.87
64.49
u/l
0.75
116
899
23
126
1.88
2.03
1.0
1.1
—
—
—
0
0
302
2807
1.50
1.99
32.6
23.1
4.01
4.01
mmol/l
0.01
297
2742
231
2052
1.36
1.99
4.8
4.1
14.93
14.99
pmol/l
0.11
202
1832
37
235
1.64
1.99
3.9
2.9
5.83
6.07
ph
1.43
21
166
294
2720
1.46
1.97
28.4
18.8
22.90
26.65
mg/l
1.42
262
2314
165
1396
1.34
1.97
9.4
6.2
9.00
9.09
%
0.18
158
1297
14
64
2.23
1.96
1.1
1.2
—
—
—
0
0
38
244
1.62
1.96
5.6
3.2
7.41
7.42
ph
0.86
31
205
166
1410
1.33
1.91
9.1
6.2
26.63
25.61
%
0.55
161
1326
164
1391
1.33
1.91
9.2
6.1
2.92
2.83
%
0.17
157
1292
153
1288
1.33
1.86
2.8
2.5
75.49
76.93
nmol/l
0.23
140
1123
6
17
3.57
1.84
1.0
1.4
—
—
—
0
0
44
299
1.54
1.80
7.3
7.8
1.32
1.29
mmol/l
0.05
44
292
11
47
2.38
1.79
1.8
3.4
—
—
—
0
0
197
1730
1.31
1.73
4.7
3.4
56.46
54.81
u/l
0.09
188
1602
7
24
2.95
1.73
1.6
1.2
—
—
—
0
0
119
975
1.33
1.72
6.2
4.5
—
—
—
0
0
14
68
2.10
1.72
3.3
3.2
—
—
—
0
0
5
13
3.88
1.72
1.0
1.8
6.40
0.84
%
—
5
8
123
1015
1.32
1.69
3.4
2.5
—
—
—
0
0
162
1390
1.30
1.67
9.5
6.2
0.68
0.62
%
0.64
155
1289
130
1086
1.31
1.63
4.1
3.4
2.36
2.35
mmol/l
0.38
117
968
5
14
3.60
1.62
1.2
1.7
79.60
73.13
%
—
5
8
42
290
1.51
1.61
2.7
2.1
378.22
394.33
nmol/l
0.21
37
269
272
2511
1.35
1.61
6.3
5.2
2.16
1.98
mu/l
0.80
250
2255
38
257
1.53
1.60
6.3
5.1
0.00
0.14
%
2.41
15
79
123
1022
1.31
1.60
8.9
5.8
—
—
—
0
0
173
1504
1.29
1.60
8.7
5.9
0.04
0.04
e9/l
0.47
148
1259
10
43
2.36
1.60
1.2
1.5
13920.00
191.25
u/l
—
5
12
7
26
2.72
1.58
1.1
1.1
—
—
—
0
0
64
482
1.40
1.57
8.9
6.9
104.86
104.35
mmol/l
0.50
64
482
25
153
1.68
1.57
5.1
3.6
25.53
24.96
mmol/l
0.54
25
147
123
1024
1.31
1.57
2.0
1.8
21.03
19.91
nmol/l
0.32
105
836
40
275
1.51
1.57
7.1
5.0
1.06
0.84
%
0.18
17
98
8
33
2.45
1.54
1.6
1.2
—
—
—
0
0
13
65
2.04
1.50
1.2
1.7
—
—
—
0
0
171
1496
1.27
1.46
8.7
5.9
0.62
0.61
e9/l
0.02
147
1252
9
38
2.40
1.46
1.0
1.5
—
—
—
0
0
7
28
2.53
1.45
1.3
1.4
29.56
37.34
ng/l
—
7
28
54
404
1.40
1.39
1.3
1.3
—
—
—
0
0
40
283
1.46
1.39
9.6
9.3
—
—
—
0
0
175
1545
1.26
1.36
8.9
6.1
0.21
0.20
e9/l
0.45
151
1323
61
468
1.36
1.35
2.2
2.0
—
—
—
0
0
71
558
1.34
1.35
1.3
1.3
2.66
2.62
g/l
0.05
44
323
10
47
2.16
1.34
1.2
1.2
—
—
—
0
0
106
883
1.28
1.32
7.8
6.4
—
—
—
0
0
172
1520
1.25
1.31
8.8
6.0
1.77
1.85
e9/l
0.37
149
1320
37
262
1.46
1.28
1.4
1.6
—
—
—
0
0
5
18
2.80
1.28
1.2
2.3
39.12
41.55
g/l
—
5
18
8
35
2.31
1.27
2.3
2.7
—
—
—
0
0
114
963
1.27
1.27
4.3
4.6
7.40
7.40
ph
0.22
88
686
26
171
1.56
1.27
6.9
3.2
—
—
—
0
0
14
77
1.85
1.27
1.6
1.5
54985.44
15669.48
e6/l
—
9
58
275
2576
1.29
1.23
8.7
7.3
41.44
40.33
mmol/mol
1.15
259
2376
25
166
1.54
1.18
1.7
2.0
0.52
3.53
ug/l
1.05
20
148
10
50
2.03
1.17
1.6
1.3
—
—
—
0
0
46
347
1.37
1.14
4.2
3.0
3.49
5.16
e9/l
1.60
36
291
14
80
1.78
1.14
2.3
2.4
121.22
124.66
g/l
—
9
61
90
752
1.26
1.09
1.5
1.4
—
—
—
0
0
16
97
1.68
1.08
6.2
5.4
—
—
—
0
0
20
129
1.58
1.07
1.4
1.3
—
—
—
0
0
279
2636
1.27
1.04
5.8
5.5
4.38
4.40
mmol/l
0.14
255
2418
7
34
2.08
1.03
3.4
3.1
322.00
749.03
mg
—
7
34
267
2512
1.25
1.03
5.0
4.6
1.39
1.26
mmol/l
1.96
240
2270
10
53
1.91
1.02
1.2
1.2
0.76
0.86
g/l
—
10
53
32
232
1.42
1.01
6.5
4.1
—
—
—
0
0
36
267
1.39
1.00
7.8
5.3
0.04
0.18
%
0.63
13
76
7
35
2.02
1.00
1.0
1.1
—
—
—
0
0
79
658
1.26
0.98
1.9
1.7
1.06
1.55
mg/l
1.58
60
522
5
23
2.19
0.98
1.4
1.2
91.20
94.74
pmol/l
—
5
23
78
649
1.26
0.98
5.7
4.2
204.62
265.07
ng/l
0.16
69
551
7
36
1.96
0.97
1.0
1.1
—
—
—
0
0
9
50
1.82
0.97
1.3
2.3
30.22
32.26
pg
—
9
50
9
50
1.82
0.97
1.2
1.2
1.45
1.61
g/l
—
9
50
35
261
1.38
0.95
7.3
4.8
0.80
0.51
%
0.33
15
86
11
62
1.80
0.95
3.8
3.3
4.43
10.45
pmol/l
3.03
11
62
295
2816
1.27
0.94
17.6
13.1
25.52
24.96
u/l
0.28
287
2716
146
1304
1.20
0.93
5.6
4.3
37.19
96.64
ng/l
0.67
112
1034
7
126
0.55
0.90
1.1
1.5
—
—
—
0
0
8
42
1.92
0.89
1.5
1.8
—
—
—
0
0
282
2685
1.24
0.87
6.6
6.4
2.54
2.54
mmol/l
0.03
257
2446
16
104
1.56
0.85
1.9
1.3
—
—
—
0
0
14
88
1.61
0.85
1.1
1.8
—
—
—
0
0
8
45
1.79
0.84
2.6
3.1
3.49
4.67
e9/l
—
8
45
143
1288
1.18
0.81
18.8
12.7
0.00
0.00
e9/l
0.62
117
1032
275
2621
1.21
0.79
5.9
5.5
1.37
1.42
mmol/l
1.24
249
2387
70
593
1.22
0.76
1.3
1.3
0.50
1.74
u/ml
1.93
16
154
47
381
1.27
0.75
1.5
1.8
—
—
—
0
0
5
24
2.10
0.74
1.0
1.0
—
—
—
0
0
5
24
2.10
0.74
1.0
1.0
—
—
—
0
0
9
55
1.65
0.74
1.6
1.4
—
—
—
0
0
9
55
1.65
0.74
1.2
1.1
—
—
—
0
0
153
1395
1.17
0.73
6.9
6.2
2.28
3.04
ug/l
1.00
140
1233
5
26
1.93
0.71
1.0
1.5
—
—
—
0
0
286
2749
1.20
0.67
26.3
16.8
—
—
—
0
0
5
28
1.79
0.66
1.4
1.9
12.42
10.77
%
—
5
28
21
155
1.38
0.64
2.8
2.5
—
—
—
0
0
22
164
1.36
0.63
1.3
1.4
—
—
—
0
0
51
429
1.22
0.61
1.5
1.3
31.63
13.03
u/ml
0.43
22
151
275
2643
1.17
0.60
6.7
5.6
6.33
6.09
mmol/l
1.90
253
2393
0
22
0.00
0.59
0.0
2.2
—
1.71
—
0
17
223
2113
1.15
0.59
33.6
25.0
330.64
331.58
g/l
0.87
223
2104
36
293
1.25
0.58
2.6
2.5
5.25
8.15
ug/l
0.83
28
257
27
212
1.29
0.57
1.2
1.2
—
—
—
0
0
6
36
1.68
0.57
1.0
1.4
—
—
—
0
0
6
38
1.59
0.54
1.2
2.0
88.58
88.67
%
—
6
38
9
64
1.42
0.52
5.4
4.1
16.67
616.17
u/ml
—
9
59
122
1121
1.13
0.50
2.0
2.0
1.40
1.29
mmol/l
0.81
103
905
54
467
1.18
0.50
1.3
1.3
25.12
34.57
iu/ml
0.57
20
149
13
93
1.41
0.48
1.1
1.2
—
3.00
—
0
9
11
153
0.71
0.47
1.3
1.3
—
39.65
—
0
10
7
49
1.44
0.46
1.1
1.1
—
—
—
0
0
5
32
1.57
0.42
1.0
1.3
—
—
—
0
0
5
32
1.57
0.42
1.8
1.4
—
—
—
0
0
44
381
1.18
0.41
4.5
4.6
3.93
41.32
ug/l
1.15
36
326
0
16
0.00
0.41
0.0
1.3
—
159.83
—
0
16
34
289
1.19
0.39
1.5
1.5
—
—
—
0
0
65
584
1.14
0.38
8.2
5.5
—
—
—
0
0
13
169
0.76
0.38
2.5
2.6
—
11.29
—
0
9
6
41
1.47
0.36
1.2
1.0
—
—
—
0
0
20
162
1.25
0.36
1.1
1.3
—
—
—
0
0
12
90
1.34
0.36
4.4
3.7
1.00
2.15
index
—
7
54
33
283
1.18
0.35
2.2
2.5
65.62
34.11
u/l
0.51
26
237
6
43
1.40
0.35
1.2
1.3
—
—
—
0
0
6
43
1.40
0.35
1.0
1.0
—
—
—
0
0
41
359
1.16
0.34
1.3
1.4
—
—
—
0
0
21
177
1.20
0.28
1.5
1.4
—
—
—
0
0
8
64
1.25
0.27
3.3
3.2
53.00
59.49
%
—
8
64
6
82
0.73
0.24
1.0
1.8
39.00
45.47
nmol/l
—
6
75
94
887
1.08
0.23
4.0
3.6
—
—
—
0
0
5
38
1.32
0.23
2.4
2.6
—
—
—
0
0
5
39
1.28
0.23
1.2
1.4
—
—
—
0
0
5
39
1.28
0.23
1.2
1.4
—
—
—
0
0
5
39
1.28
0.23
1.2
1.4
—
—
—
0
0
5
39
1.28
0.23
1.2
1.4
—
—
—
0
0
5
39
1.28
0.23
1.4
1.2
0.97
1.62
u/ml
—
5
26
26
229
1.14
0.22
4.0
4.0
—
—
—
0
0
5
41
1.22
0.22
3.0
2.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
5.1
—
50.59
—
0
11
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
8
104
0.76
0.21
1.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.6
—
155.88
—
0
8
0
13
0.00
0.21
0.0
1.2
—
156.59
—
0
13
77
815
0.93
0.20
4.4
3.5
0.75
0.82
ug/l
0.28
61
582
5
67
0.74
0.17
1.8
1.5
—
—
—
0
0
8
72
1.11
0.16
1.0
1.2
—
—
—
0
0
17
152
1.12
0.12
5.8
4.7
36.74
36.91
°c
0.74
17
152
5
65
0.77
0.08
1.8
1.3
74.00
57.90
mmol/l
—
5
58
7
65
1.08
0.08
1.1
1.2
—
—
—
0
0
24
255
0.94
0.07
1.7
1.4
—
—
—
0
0
14
150
0.93
0.04
3.0
3.2
11.14
2362.41
u/ml
1.29
14
130
10
107
0.93
0.02
3.3
1.9
20.40
21.21
s
—
10
100
15
157
0.95
0.01
1.3
1.5
—
—
—
0
0
68
685
0.99
0.00
3.9
3.2
2.48
2.46
mmol/l
0.79
61
615
15
147
1.02
0.00
1.2
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
3.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
45.68
—
0
5
0
5
0.00
0.00
0.0
1.8
—
149.60
—
0
5
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
25.6
—
1155.13
—
0
8
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
1.17
—
0
8
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
9
95
0.94
-0.00
1.1
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
9
94
0.96
-0.00
8.2
10.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
51.00
—
0
6
0
7
0.00
-0.00
0.0
1.1
—
40.14
—
0
7
0
6
0.00
-0.00
0.0
1.2
—
26.67
—
0
6

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_BLADDER and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_BLADDER 1.365 [1.11, 1.68] 0.004
Birth year 0.991 [0.98, 1.0] 0.048

During the follow-up period (1.1.1998 — 31.12.2019), 171 out of 564 females with CD2_BENIGN_BLADDER died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_BLADDER 1.415 [1.17, 1.7] < 0.001
Birth year 0.988 [0.98, 1.0] 0.011

During the follow-up period (1.1.1998 — 31.12.2019), 343 out of 846 males with CD2_BENIGN_BLADDER died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_BLADDER.

N-year risk Females Males
1 0.114% 0.309%
5 0.766% 1.871%
10 1.776% 4.391%
15 3.311% 8.048%
20 5.832% 13.67%

Relationships between endpoints

Index endpoint: CD2_BENIGN_BLADDER – Benign neoplasm: Bladder

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data