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Acute myeloid leukaemia, helper endpoint

HLP_C3_AML

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cancer registry: Topography ICD-O-3 ANY
  • Cancer registry: Morphology ICD-O-3 9840|9861|986[67]|987[1-4]|989[1567]|9910|9920|993[01]
  • Cancer registry: Behaviour codes 3

1 out of 7 registries used, show all original rules.

1358

4. Check minimum number of events

None

1358

5. Include endpoints

None

1358

6. Filter based on genotype QC (FinnGen only)

470

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 470 200 270
Unadjusted period prevalence (%) 0.10 0.07 0.12
Median age at first event (years) 68.47 65.09 70.98

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
509
Matched controls
5090
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A04AA01
ATC
ondansetron; systemic, rectal
57.9
317.3
188
51
XW000
NOMESCO Finland
Bone marrow biopsy
148.5
307.7
308
52
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
+∞
307.7
457
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
6849.1
307.7
373
*
WW500
NOMESCO Finland
Blood transfusion
87.5
307.7
202
38
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
+∞
307.7
344
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
53.3
236.7
140
36
127
Kela drug reimbursment
Transplant complication
73.7
166.8
91
15
A05AA02
ATC
ursodeoxycholic acid; oral
54.3
148.6
86
19
Z51.5
ICD-10 Finland
Palliative care
15.1
137.9
137
121
L03AA02
ATC
filgrastim; parenteral
1597.8
131.3
122
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
8.8
116.3
189
320
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
13.2
111.3
118
114
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
1073.5
94.0
89
*
H02AB02
ATC
dexamethasone; systemic
38.4
92.6
58
17
JN4AD
NOMESCO Finland
Body CT examination
9.9
88.0
114
144
ZX112
NOMESCO Finland
Subcutaneous
42.1
86.9
53
14
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
7.2
85.5
159
303
J05AB11
ATC
valaciclovir; oral
6.5
84.9
182
399
C95.0
ICD-10 Finland
Acute leukaemia of unspecified cell type
+∞
84.8
79
*
R50.9
ICD-10 Finland
Fever, unspecified
6.3
83.0
185
420
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
42.5
82.2
50
13
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
902.6
80.7
77
*
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
20.4
79.8
63
35
M04AA01
ATC
allopurinol; systemic
5.9
77.9
193
480
J01MA12
ATC
levofloxacin; systemic
5.5
74.2
204
553
L04AD01
ATC
ciclosporin; systemic
29.1
73.4
50
19
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
8.8
71.3
100
138
JN4BD
NOMESCO Finland
Extensive body CT
10.1
68.2
84
98
ZX120
NOMESCO Finland
Intravenous
8.0
67.2
102
154
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
714.7
65.4
63
*
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
14.3
65.2
62
49
J02AC03
ATC
voriconazole; systemic
361.7
63.9
63
*
D64.9
ICD-10 Finland
Anaemia, unspecified
5.5
63.9
157
381
L01XX05
ATC
hydroxycarbamide; oral
637.7
58.9
57
*
L01BB02
ATC
mercaptopurine; oral
28.9
58.7
40
15
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
321.4
57.5
57
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
8.0
56.4
84
123
D70.89
ICD-10 Finland
Neutropenic splenomegaly
111.0
55.1
59
6
N02AA05
ATC
oxycodone; systemic
4.6
54.2
172
508
A04AA02
ATC
granisetron; systemic, transdermal
550.4
51.4
50
*
A03FA01
ATC
metoclopramide; systemic, rectal
4.9
49.4
135
352
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
48.7
46
*
D46.2
ICD-10 Finland
Refractory anaemia with excess of blasts [RAEB]
+∞
46.6
44
*
A41.9
ICD-10 Finland
Sepsis, unspecified
7.8
45.6
68
99
121
Kela drug reimbursment
Severe hypofunction of sexual glands
16.8
45.6
39
25
TPX10
NOMESCO Finland
Implantation of vascular injection port
13.7
44.9
43
34
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
465.6
43.9
43
*
D46.7
ICD-10 Finland
Other myelodysplastic syndromes
228.3
41.5
42
*
TGC00
NOMESCO Finland
Bronchial lavation
9.5
40.3
50
58
WW200
NOMESCO Finland
Immunization
10.4
40.1
46
48
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
70.3
39.8
45
7
B73
ICPC
Leukaemia
+∞
39.1
37
*
J01MA14
ATC
moxifloxacin; systemic
4.9
39.0
99
240
399
Kela drug reimbursment
Venetoclax
+∞
38.0
36
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
36.9
35
*
1518, ,
Kela drug reimbursment
+∞
35.9
34
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
35.9
34
*
9891/3-C42.1
ICD-O-3
Acute monocytic leukemia of bone marrow
+∞
35.9
34
*
B03XA02
ATC
darbepoetin alfa; parenteral
12.4
35.5
36
31
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.6
35.3
156
563
L03AA13
ATC
pegfilgrastim; parenteral
193.3
35.2
36
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.2
34.7
320
1773
L04AA06
ATC
mycophenolic acid; systemic
12.9
34.5
34
28
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
360.1
34.3
34
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
360.1
34.3
34
*
WZC00
NOMESCO Finland
Treatment plan or consultation
3.2
34.1
197
835
L01XX52
ATC
venetoclax; oral
+∞
33.7
32
*
WW306
NOMESCO Finland
Transfer of stem cells from foreign registered donator
+∞
33.7
32
*
J02AC04
ATC
posaconazole; systemic
+∞
33.7
32
*
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
6.5
33.4
58
99
C92.5
ICD-10 Finland
Acute myelomonocytic leukaemia
+∞
31.6
30
*
C92.1
ICD-10 Finland
Chronic myeloid leukaemia [CML], BCR/ABL-positive
+∞
30.5
29
*
C95.9
ICD-10 Finland
Leukaemia, unspecified
+∞
30.5
29
*
Y84.8
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
34.1
29.5
38
12
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
+∞
29.5
28
*
C92.4
ICD-10 Finland
Acute promyelocytic leukaemia [PML]
+∞
28.4
27
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
6.1
27.5
50
89
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
6.2
27.3
49
86
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
79.7
27.1
30
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.7
26.7
67
159
212
Kela drug reimbursment
Gout
7.8
26.6
38
52
115
Kela drug reimbursment
Breast cancer
+∞
26.3
25
*
D47.1
ICD-10 Finland
Chronic myeloproliferative disease
+∞
26.3
25
*
WW302
NOMESCO Finland
Allogenic transfer of stem cells from relative
+∞
26.3
25
*
J05AB01
ATC
aciclovir; systemic
3.0
26.2
149
613
H02AB09
ATC
hydrocortisone; systemic
8.9
25.1
32
38
GD1AD
NOMESCO Finland
Thorax CT examination
4.9
25.0
58
129
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
10.5
24.9
28
28
D45
ICD-10 Finland
Polycythaemia vera
262.3
24.9
25
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
23.1
22
*
WW409
NOMESCO Finland
Other aferesis
+∞
23.1
22
*
D47.3
ICD-10 Finland
Essential (haemorrhagic) thrombocythaemia
+∞
23.1
22
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
4.3
22.9
64
165
D70.82
ICD-10 Finland
Drug-induced neutropenia
87.5
22.9
25
*
TPH00
NOMESCO Finland
Phlebotomy
125.7
22.8
24
*
9873/3-C42.1
ICD-O-3
Acute myeloid leukemia without maturation of bone marrow
+∞
22.0
21
*
9989/3-C42.1
ICD-O-3
Myelodysplastic syndrome, NOS, of bone marrow
+∞
22.0
21
*
C92.9
ICD-10 Finland
Myeloid leukaemia, unspecified
+∞
22.0
21
*
2050A
ICD-9 Finland
Myeloid leukaemia, Acute
+∞
22.0
21
*
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
35.5
21.3
27
8
JN6AD
NOMESCO Finland
CT of torso and neck
29.5
21.2
28
10
116
Kela drug reimbursment
Prostate cancer
+∞
21.0
20
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
5.4
20.6
42
83
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
50.2
20.3
24
5
D64.8
ICD-10 Finland
Other specified anaemias
8.8
20.3
26
31
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
7.1
20.2
31
46
A41.1
ICD-10 Finland
Sepsis due to other specified staphylococcus
21.9
20.2
29
14
9920/3-C42.1
ICD-O-3
Therapy-related myeloid neoplasm of bone marrow
+∞
19.9
19
*
WD515
NOMESCO Finland
Demanding therapy of malignancy with enzyme inhibitors and similar treatments
+∞
19.9
19
*
9895/3-C42.1
ICD-O-3
Acute myeloid leukemia with myelodysplasia-related changes of bone marrow
+∞
19.9
19
*
9961/3-C42.1
ICD-O-3
Primary myelofibrosis of bone marrow
+∞
19.9
19
*
A41.8
ICD-10 Finland
Other specified sepsis
8.1
19.7
27
35
C90.0
ICD-10 Finland
Multiple myeloma
207.7
19.7
20
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.8
18.9
62
179
9950/3-C42.1
ICD-O-3
Polycythemia vera of bone marrow
+∞
18.9
18
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
72.7
18.8
21
*
J02AC01
ATC
fluconazole; systemic
2.4
18.8
200
1094
WF002
NOMESCO Finland
Radical radiotherapy
103.9
18.7
20
*
ZX121
NOMESCO Finland
Central venous catheter
197.0
18.7
19
*
L02AE02
ATC
leuprorelin; implant, parenteral
69.2
17.8
20
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
17.8
17
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
17.8
17
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
17.8
17
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
186.2
17.6
18
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.7
17.6
59
173
L04AD02
ATC
tacrolimus; systemic
30.0
17.6
23
8
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.3
17.5
199
1113
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
5.5
17.3
34
65
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
14.7
17.0
28
20
JN3AD
NOMESCO Finland
Abdominal CT examination
3.1
16.9
81
297
ZX090
NOMESCO Finland
Other technic of radiotherapy
65.6
16.8
19
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
16.8
16
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
16.8
16
*
9874/3-C42.1
ICD-O-3
Acute myeloid leukemia with maturation of bone marrow
+∞
16.8
16
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
16.8
16
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.0
16.6
82
306
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.2
16.5
198
1125
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
6.1
16.4
29
50
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
5.5
16.3
32
61
B02AA02
ATC
tranexamic acid; systemic
3.0
15.7
79
297
9983/3-C42.1
ICD-O-3
Myelodysplastic syndrome with excess blasts of bone marrow
+∞
15.7
15
*
HAC20
NOMESCO Finland
Total mastectomy
+∞
15.7
15
*
1DB06, ,
NOMESCO Finland
+∞
15.7
15
*
C93.0
ICD-10 Finland
Acute monoblastic/monocytic leukaemia
+∞
15.7
15
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.3
15.6
167
902
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
164.9
15.6
16
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.4
15.2
134
665
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
4.9
15.2
34
73
SPAT1088
SPAT
Blood transfusion
32.8
14.9
19
6
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
58.5
14.9
17
*
J05AX18
ATC
letermovir; oral
+∞
14.7
14
*
130
Kela drug reimbursment
Malignant tumour
+∞
14.7
14
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
14.7
14
*
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
154.2
14.5
15
*
XX3DW
NOMESCO Finland
Time consuming IT work
4.4
14.4
37
89
HA1AA
NOMESCO Finland
X-ray mammography
5.3
13.8
28
55
L03AB05
ATC
interferon alfa-2b; parenteral
+∞
13.6
13
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
13.6
13
*
9867/3-C42.1
ICD-O-3
Acute myelomonocytic leukemia, NOS, of bone marrow
+∞
13.6
13
*
D75.9
ICD-10 Finland
Disease of blood and blood-forming organs, unspecified
35.1
13.6
17
5
L04AA01
ATC
[U] ciclosporin
16.8
13.6
21
13
TAB00
NOMESCO Finland
Lumbar puncture
4.2
13.4
37
94
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
6.5
13.4
22
35
L02BG04
ATC
letrozole; oral
29.2
13.0
17
6
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.2
12.7
53
178
J02AC05
ATC
isavuconazole; systemic
+∞
12.5
12
*
A79
ICPC
Malignancy NOS
+∞
12.5
12
*
9866/3-C42.1
ICD-O-3
Acute promyelocytic leukemia, t(15;17)(q22;q11-12) of bone marrow
+∞
12.5
12
*
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
12.5
12
*
1BC07, ,
NOMESCO Finland
+∞
12.5
12
*
WW304
NOMESCO Finland
Transfer of stem cells from registered domestic donator
+∞
12.5
12
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
12.5
12
*
306
Kela drug reimbursment
Erythropoietin and darbepoetin
133.2
12.5
13
*
Y77
ICPC
Malignant neoplasm prostate
133.2
12.5
13
*
L02BA01
ATC
tamoxifen; oral
133.2
12.5
13
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.8
12.2
67
263
H02AB06
ATC
prednisolone; systemic
1.9
12.1
255
1734
JN4CD
NOMESCO Finland
Very extensive body CT
10.0
11.9
23
24
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.5
11.6
80
352
9962/3-C42.1
ICD-O-3
Essential thrombocythemia of bone marrow
+∞
11.5
11
*
C92.3
ICD-10 Finland
Myeloid sarcoma
+∞
11.5
11
*
2AX04, ,
NOMESCO Finland
+∞
11.5
11
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
11.5
11
*
TNE20
NOMESCO Finland
Bone marrow aspiration, pelvis
122.7
11.5
12
*
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
17.5
11.3
17
10
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.9
10.8
206
1340
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
4.7
10.8
25
55
B03XA01
ATC
erythropoietin; parenteral
18.3
10.8
16
9
B01AB05
ATC
enoxaparin; parenteral
2.0
10.7
162
976
B25.9
ICD-10 Finland
Cytomegaloviral disease, unspecified
61.3
10.7
12
*
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
61.3
10.7
12
*
ZXD05
NOMESCO Finland
Urgent procedure
2.0
10.6
159
954
A40.8
ICD-10 Finland
Other streptococcal sepsis
10.4
10.6
20
20
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
112.2
10.5
11
*
L02BB03
ATC
bicalutamide; oral
+∞
10.4
10
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
10.4
10
*
1DB07, ,
NOMESCO Finland
+∞
10.4
10
*
XW4XT
NOMESCO Finland
Biopsy of other inner organ with radiological guidance guidance
+∞
10.4
10
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
10.4
10
*
Z85.6
ICD-10 Finland
Personal history of leukaemia
+∞
10.4
10
*
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
23.9
10.3
14
6
A02BC02
ATC
pantoprazole; systemic
1.9
10.1
338
2608
NK6AN
NOMESCO Finland
Total body bone isotope imaging
40.9
10.0
12
*
D75.2
ICD-10 Finland
Essential thrombocytosis
40.9
10.0
12
*
J01MA02
ATC
ciprofloxacin; systemic
1.8
10.0
212
1420
H02AB04
ATC
methylprednisolone; systemic
2.2
9.9
90
446
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
5.1
9.9
21
43
WPA10
NOMESCO Finland
Proactive palliative care treatment plan
26.6
9.9
13
5
D46.3
ICD-10 Finland
Refractory anemia with excess of blasts with transformation
56.1
9.7
11
*
N05BA06
ATC
lorazepam; systemic, sublingual
3.0
9.6
43
151
D11AH01
ATC
tacrolimus; topical
15.4
9.6
15
10
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
101.9
9.4
10
*
WVA30
NOMESCO Finland
Intramuscular and subcutaneous injection
30.7
9.4
12
*
A49.8
ICD-10 Finland
Other bacterial infections of unspecified site
12.7
9.4
16
13
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
9.4
9
*
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
+∞
9.4
9
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
9.4
9
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
9.4
9
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
9.4
9
*
174
Kela drug reimbursment
Ruxolitinib
+∞
9.4
9
*
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
+∞
9.4
9
*
D46.0
ICD-10 Finland
Refractory anaemia without ring sideroblasts, so stated
+∞
9.4
9
*
SPAT1074
SPAT
Venesection
37.4
9.0
11
*
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.8
9.0
249
1790
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.6
9.0
53
216
D72.9
ICD-10 Finland
Disorder of white blood cells, unspecified
50.9
8.7
10
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
50.9
8.7
10
*
ZXE00
NOMESCO Finland
One hour or less
1.8
8.6
187
1248
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
10.3
8.6
16
16
B74
ICPC
Malignant neoplasm blood other
+∞
8.4
8
*
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
+∞
8.4
8
*
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
+∞
8.4
8
*
128
Kela drug reimbursment
Cancers of female genital organs
+∞
8.4
8
*
A04AD12
ATC
aprepitant; systemic
+∞
8.4
8
*
374
Kela drug reimbursment
Ruxolitinib
+∞
8.4
8
*
9872/3-C42.1
ICD-O-3
Acute myeloid leukemia, minimal differentiation of bone marrow
+∞
8.4
8
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
8.4
8
*
A07AA09
ATC
vancomycin; oral
9.7
8.3
16
17
R4110
NOMESCO Finland
Physiotherapy
1.9
8.1
135
828
WW200, ,
SPAT
0.4
8.0
54
1095
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.8
7.9
40
150
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.8
7.7
23
62
B99
ICD-10 Finland
Other and unspecified infectious diseases
4.6
7.7
18
40
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
18.7
7.6
11
6
5BA08, ,
NOMESCO Finland
18.7
7.6
11
6
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
18.7
7.6
11
6
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
3.1
7.6
31
103
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
25.4
7.6
10
*
R72
ICD-10 Finland
Abnormality of white blood cells, not elsewhere classified
25.4
7.6
10
*
A07AA02
ATC
nystatin; oral
2.8
7.5
38
143
JN6DR
NOMESCO Finland
PET-CT of whole body metabolism
13.6
7.4
12
9
D89.89
ICD-10 Finland
Other specified disorders involving the immune mechanism, not elsewhere classified
+∞
7.3
7
*
HA013
NOMESCO Finland
Radiotherapy after total ablation of mammary gland
+∞
7.3
7
*
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
7.3
7
*
20500
ICD-8 Finland
Myeloid leukaemia, Acute
+∞
7.3
7
*
9945/3-C42.1
ICD-O-3
Chronic myelomonocytic leukemia, NOS, of bone marrow
+∞
7.3
7
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
7.3
7
*
C50.11
ICD-10 Finland
Malignant tumor of the central part of the mammary gland,ductal tumor
+∞
7.3
7
*
N05AX08
ATC
risperidone; systemic
0.2
7.3
8
362
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
30.5
7.2
9
*
A98
ICPC
Health maint/preventive medicine
0.6
6.9
363
4134
Z3231
NOMESCO Finland
Registered nurse
1.8
6.9
131
833
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
4.2
6.9
18
44
Z76.0
ICD-10 Finland
Issue of repeat prescription
0.4
6.9
40
864
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
6.2
6.8
17
28
TPX15
NOMESCO Finland
Removal of vascular injection port
40.6
6.8
8
*
ED1AA
NOMESCO Finland
Mandibular X-ray examination
40.6
6.8
8
*
M87.1
ICD-10 Finland
Osteonecrosis due to drugs
40.6
6.8
8
*
D61.9
ICD-10 Finland
Aplastic anaemia, unspecified
40.6
6.8
8
*
WVA20
NOMESCO Finland
Medicine administration
4.0
6.8
19
49
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
17.0
6.8
10
6
G30.1
ICD-10 Finland
Alzheimer disease with late onset
0.2
6.7
7
327
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
4.1
6.7
18
45
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
10.2
6.6
12
12
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.8
6.5
33
124
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
2.4
6.5
43
185
ZX070
NOMESCO Finland
Intensity modified radiotherapy
70.7
6.4
7
*
L02BG06
ATC
exemestane; oral
70.7
6.4
7
*
WZC30
NOMESCO Finland
Teaching
2.1
6.4
64
328
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
6.4
147
983
ZX100
NOMESCO Finland
Oral
6.7
6.4
15
23
J01FF01
ATC
clindamycin; systemic
1.7
6.3
133
869
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.9
6.3
29
104
C54.11
ICD-10 Finland
Adenocarcinoma of the endometrium
+∞
6.3
6
*
C92.7
ICD-10 Finland
Other myeloid leukaemia
+∞
6.3
6
*
6BA02, ,
NOMESCO Finland
+∞
6.3
6
*
L03AB04
ATC
interferon alfa-2a; parenteral
+∞
6.3
6
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
6.3
6
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
6.3
6
*
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
+∞
6.3
6
*
C44.61
ICD-10 Finland
Basocellular carcinoma of the skin of the upper extremity including the shoulder
+∞
6.3
6
*
C92.2
ICD-10 Finland
Atypical chronic myeloid leukaemia, BCR/ABL- negative
+∞
6.3
6
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
6.3
6
*
E89.4
ICD-10 Finland
Postprocedural ovarian failure
+∞
6.3
6
*
D46.1
ICD-10 Finland
Refractory anaemia with ring sideroblasts
+∞
6.3
6
*
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
+∞
6.3
6
*
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
6.3
6
*
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
+∞
6.3
6
*
C92
ICD-10 Finland
Myeloid leukaemia
+∞
6.3
6
*
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
+∞
6.3
6
*
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
+∞
6.3
6
*
D61.0
ICD-10 Finland
Constitutional aplastic anaemia
+∞
6.3
6
*
T86.9
ICD-10 Finland
Failure and rejection of unspecified transplanted organ and tissue
+∞
6.3
6
*
A02BC01
ATC
omeprazole; systemic
1.7
6.3
142
946
HA1AT
NOMESCO Finland
Biopsy of mammary glands with ultrasound guidance
27.0
6.2
8
*
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
27.0
6.2
8
*
N05CF01
ATC
zopiclone; oral
1.6
6.2
171
1198
D07AB08
ATC
desonide; topical
2.1
6.2
58
290
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.5
6.1
38
159

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
167
23
107.58
320.45
1.4
1.2
—
—
—
0
0
202
17
196.35
307.65
1.4
1.0
—
—
—
0
0
216
39
95.48
307.65
6.1
1.3
—
—
—
0
0
163
52
45.64
261.36
1.6
1.5
141.90
152.66
au/ml
0.25
41
19
121
11
143.99
241.61
1.7
1.0
—
—
—
0
0
174
87
29.87
238.48
1.4
1.3
—
—
—
0
0
152
58
36.94
229.52
1.4
1.4
—
—
—
0
0
147
62
32.93
213.89
1.4
1.3
250.56
201.38
u/ml
0.51
88
29
136
60
30.57
193.96
1.2
1.0
—
—
—
0
0
287
557
10.52
162.84
8.4
2.1
1.85
1.74
%
0.76
281
495
103
34
37.73
160.94
12.5
2.5
0.78
0.57
%
0.40
98
28
251
422
10.76
160.58
8.3
2.2
60.14
65.94
e9/l
1.14
208
330
205
268
12.13
159.78
3.2
2.1
9.97
11.27
g/l
3.22
200
251
171
203
12.18
141.77
1.5
1.4
—
—
—
0
0
175
217
11.77
140.48
1.5
1.3
1.14
1.19
g/l
0.21
169
207
207
325
10.05
137.97
13.7
4.0
1.41
0.70
%
2.80
183
76
103
63
20.24
126.11
1.3
1.0
—
—
—
0
0
198
347
8.70
118.38
1.6
1.5
—
—
—
0
0
154
204
10.39
116.17
1.7
1.7
1.52
1.53
g/l
0.06
136
179
184
307
8.82
114.57
14.0
4.0
0.93
0.40
%
4.84
163
72
207
397
8.10
113.51
1.7
1.5
—
—
—
0
0
247
571
7.46
112.92
15.6
5.1
1.09
1.03
mmol/l
2.96
242
512
108
91
14.80
110.89
1.8
1.3
—
—
—
0
0
81
45
21.22
103.14
2.6
1.5
—
—
—
0
0
81
45
21.22
103.14
2.6
1.5
—
—
—
0
0
81
45
21.22
103.14
2.6
1.5
—
—
—
0
0
81
45
21.22
103.14
2.6
1.5
—
—
—
0
0
175
322
7.76
98.45
14.6
4.4
10.01
0.00
%
8.15
153
56
96
5
235.88
96.05
1.0
1.0
—
—
—
0
0
170
313
7.65
95.32
14.5
4.1
0.20
0.06
%
2.03
147
63
95
5
232.86
94.95
1.5
1.0
—
—
—
0
0
242
634
6.37
94.57
4.9
1.9
29.00
29.78
s
1.12
237
612
207
494
6.38
88.74
1.7
1.8
—
—
—
0
0
234
633
5.99
87.19
13.0
2.9
0.80
0.83
mmol/l
3.12
226
586
53
15
39.32
85.31
4.7
1.5
26.15
45.21
%
2.47
53
15
172
357
6.77
84.93
2.3
1.5
65.79
66.81
g/l
0.87
167
325
302
1075
5.45
80.05
11.5
2.5
309.07
356.33
umol/l
7.29
293
914
75
5
175.41
73.18
4.4
1.0
—
—
—
0
0
305
1188
4.91
69.70
20.6
4.0
—
—
—
0
0
305
1251
4.59
63.49
31.3
5.3
—
—
—
0
0
82
106
9.03
61.31
1.5
2.2
28.91
12.01
mg/l
1.36
66
99
242
855
4.49
61.19
3.4
1.7
3.86
1.29
mg/l
3.53
219
664
67
71
10.72
58.14
1.3
1.2
191.66
16.89
u/l
4.43
61
62
355
1791
4.25
51.73
29.6
5.6
10.52
8.90
%
2.98
347
1665
48
0
+∞
50.89
1.0
0.0
—
—
—
0
0
352
1790
4.13
50.10
28.9
5.5
1.68
2.99
%
32.07
345
1667
47
0
+∞
49.81
1.0
0.0
—
—
—
0
0
47
0
+∞
49.81
1.0
0.0
—
—
—
0
0
47
0
+∞
49.81
1.0
0.0
—
—
—
0
0
47
0
+∞
49.81
1.0
0.0
—
—
—
0
0
355
1827
4.12
49.37
29.5
5.6
33.22
26.68
%
12.51
349
1720
350
1792
4.05
48.86
29.1
5.6
0.63
0.67
%
0.50
344
1664
203
742
3.89
46.73
1.5
1.3
2.42
2.72
g/l
1.59
180
435
36
19
20.31
46.14
2.3
1.8
40.24
47.24
%
0.71
17
11
268
1188
3.65
45.79
18.6
2.1
—
—
—
0
0
50
6
92.29
45.76
1.2
1.0
—
—
—
0
0
47
44
11.67
44.14
1.2
1.2
—
—
—
0
0
117
299
4.78
43.48
1.6
1.4
—
—
—
0
0
335
1808
3.49
39.98
26.6
5.5
46.18
58.18
%
27.73
328
1715
45
51
9.58
36.84
5.9
1.9
33.24
33.16
pg
0.04
45
51
135
435
3.86
36.29
16.5
2.4
8.14
8.70
umol/l
0.10
130
378
347
2010
3.28
34.86
34.4
4.0
11.43
12.37
umol/l
1.06
342
1895
208
906
3.19
34.42
17.5
2.0
—
—
—
0
0
213
942
3.17
34.31
2.4
1.3
—
—
—
0
0
313
1724
3.12
34.06
18.4
2.4
—
—
estimate
—
0
0
193
819
3.19
33.19
19.9
4.3
—
—
—
0
0
353
2114
3.19
32.49
59.9
6.4
3.22
4.33
e9/l
2.10
335
1820
311
1806
2.86
28.96
18.7
3.9
32.39
35.43
g/l
15.88
302
1669
335
2036
2.89
28.35
30.2
5.6
0.11
0.20
e9/l
23.51
301
1764
325
1970
2.80
27.19
25.0
5.5
0.67
0.60
e9/l
0.29
295
1677
325
1978
2.78
26.83
25.0
5.5
0.03
0.04
e9/l
1.72
295
1689
328
2006
2.79
26.81
25.4
5.6
1.85
1.81
e9/l
0.08
305
1751
316
1897
2.76
26.80
19.4
5.8
1.20
1.21
mmol/l
2.61
306
1713
60
133
4.98
25.95
1.3
1.2
30.38
48.96
mg/l
3.53
51
115
56
117
5.25
25.92
1.3
1.2
1.36
1.41
ratio
0.12
38
72
43
70
6.62
25.78
1.4
1.2
—
—
—
0
0
31
35
9.37
25.31
1.4
1.1
—
—
—
0
0
338
2138
2.73
25.16
23.7
6.2
1.20
1.21
mmol/l
1.35
296
1845
143
596
2.95
24.35
2.4
1.9
—
—
—
0
0
58
133
4.79
24.06
1.3
1.2
26.54
35.72
mg/l
1.59
50
116
41
69
6.37
23.78
7.2
2.7
44.76
59.07
%
4.95
41
69
21
0
+∞
22.03
1.9
0.0
21.62
—
%
—
21
0
121
486
2.95
21.81
4.1
1.4
—
—
—
0
0
26
6
45.49
21.60
4.3
1.3
37.42
20.83
%
—
26
6
143
670
2.58
18.85
1.9
2.5
2.01
2.25
g/l
6.26
137
614
220
1259
2.32
18.52
6.7
2.7
29.38
34.33
u/l
1.50
212
1185
22
5
45.83
18.37
10.6
3.8
37.41
61.90
%
—
22
5
218
1246
2.31
18.37
18.0
3.1
7.41
7.40
ph
2.25
172
894
133
614
2.58
17.98
1.9
2.6
36.20
23.07
%
9.21
126
567
67
223
3.31
16.42
1.6
1.5
—
—
—
0
0
25
15
17.45
16.24
1.2
1.1
—
—
—
0
0
26
44
6.17
14.93
3.0
1.7
2.50
10463.90
u/l
—
6
9
19
6
32.80
14.90
2.1
1.5
—
—
—
0
0
106
477
2.54
14.87
2.0
1.8
—
—
—
0
0
35
79
4.68
14.71
1.1
1.3
74.09
302.02
miu/ml
—
7
26
338
2436
2.15
14.67
14.1
4.7
6.81
6.78
mmol/l
0.11
333
2320
197
1186
2.08
13.63
2.3
2.3
2.94
2.86
mg/l
0.16
166
1009
13
0
+∞
13.60
1.2
0.0
—
—
—
0
0
293
2046
2.02
13.29
15.6
18.3
1.28
1.34
inr
1.36
272
1724
271
1846
2.00
13.14
4.3
3.0
711.23
125.71
ug/l
7.01
260
1709
16
5
32.96
12.64
1.3
1.0
—
—
—
0
0
155
904
2.03
11.32
4.5
4.4
65.92
359.66
ng/l
2.83
127
761
208
1347
1.92
11.18
4.8
3.5
—
—
—
0
0
197
1275
1.89
10.44
4.0
2.3
47.61
61.55
u/l
2.91
184
1172
53
205
2.77
9.92
4.3
1.4
3.10
2.70
ug/l
0.29
40
151
29
77
3.93
9.91
2.7
1.2
—
—
—
0
0
205
1372
1.83
9.58
5.7
2.1
2.30
2.35
mmol/l
5.08
187
1183
16
13
12.66
9.41
1.1
1.2
—
—
—
0
0
21
29
7.50
9.30
1.4
1.1
—
—
—
0
0
18
20
9.29
9.09
2.3
2.6
1620.56
704.15
u/ml
1.32
18
20
80
392
2.23
9.04
13.6
4.0
7.40
7.37
ph
1.25
75
265
73
345
2.30
8.98
1.8
2.1
0.21
0.20
g/l
0.36
65
315
12
5
24.51
8.94
8.7
1.6
2.08
3.60
%
—
12
5
68
313
2.35
8.88
6.9
4.2
7.43
7.41
ph
1.37
56
258
107
594
2.01
8.73
12.6
6.2
104.75
104.27
mmol/l
0.58
107
594
53
223
2.54
8.40
7.9
4.3
—
—
—
0
0
117
679
1.94
8.37
4.7
3.0
2.67
2.56
e6/l
0.04
64
334
201
1385
1.75
8.21
5.1
3.2
49.48
122.32
e6/l
0.75
161
1067
143
896
1.83
8.04
2.0
1.8
1265.36
1153.08
nmol/l
0.71
127
679
103
1649
0.53
7.65
3.0
1.9
1.68
1.30
mmol/l
4.66
95
1376
19
45
4.35
7.53
1.7
2.7
—
—
—
0
0
29
93
3.25
7.53
2.7
1.3
35.37
1440.53
e6/l
0.67
24
79
331
3877
0.58
7.40
5.3
6.3
2.52
2.59
mmol/l
0.68
309
3557
13
12
11.08
7.33
1.0
1.0
—
—
—
0
0
11
7
16.02
7.25
1.2
1.9
—
—
—
0
0
170
1150
1.72
7.23
2.6
1.7
—
—
—
0
0
17
39
4.48
7.01
2.6
1.1
—
—
—
0
0
28
92
3.16
7.00
2.8
1.2
13.17
63.36
e6/l
0.46
23
77
27
87
3.22
6.96
2.3
1.3
3.72
3.98
mmol/l
0.72
27
82
60
292
2.20
6.86
5.5
4.2
—
—
—
0
0
172
1186
1.68
6.73
5.0
3.1
0.65
0.44
e6/l
0.33
133
873
267
2065
1.62
6.56
2.4
2.3
90.55
95.67
pmol/l
1.04
203
1046
211
1541
1.63
6.55
6.0
3.9
44.76
120.19
e6/l
1.88
168
1102
318
3725
0.61
6.45
5.9
7.2
39.26
40.21
mmol/mol
1.37
299
3456
43
186
2.43
6.44
1.7
1.3
—
—
—
0
0
326
2655
1.63
6.42
7.0
4.9
222.00
3576.53
e6/l
1.42
11
47
29
103
2.93
6.37
2.7
1.2
498.72
522.99
mg/l
0.10
29
96
18
47
3.93
6.31
1.2
1.1
—
—
—
0
0
205
1510
1.60
6.02
3.1
3.4
1171.24
1638.19
ng/l
1.88
193
1301
230
1743
1.58
5.97
45.6
10.0
0.11
0.00
e9/l
0.73
190
1425
86
502
1.86
5.93
5.0
3.7
7.38
7.38
ph
0.06
60
308
57
290
2.09
5.82
1.6
1.1
—
—
—
0
0
84
494
1.84
5.65
8.6
2.9
3.97
4.95
e9/l
0.70
74
416
83
487
1.84
5.62
5.0
3.6
2.05
1.94
mmol/l
0.09
71
425
327
3766
0.63
5.53
4.9
5.3
1.25
1.45
mmol/l
14.30
302
3442
22
77
2.94
4.98
4.4
3.3
—
—
—
0
0
63
353
1.90
4.92
2.3
2.0
80.34
34.25
u/l
0.47
56
287
186
1393
1.53
4.84
2.1
1.8
18.96
20.05
nmol/l
0.48
178
1181
380
4198
0.63
4.76
103.5
23.3
106.90
134.78
g/l
94.25
375
4129
87
544
1.72
4.73
7.8
6.9
7.43
7.42
ph
1.62
64
329
380
4196
0.63
4.71
102.9
23.1
9.03
6.79
e9/l
0.61
372
4069
380
4196
0.63
4.71
102.9
23.1
3.59
4.46
e12/l
65.13
372
4070
380
4196
0.63
4.71
103.5
23.6
32.33
40.18
%
79.84
375
4126
380
4196
0.63
4.71
102.6
23.0
31.01
30.41
pg
5.55
375
4126
380
4196
0.63
4.71
103.1
23.1
156.10
242.23
e9/l
35.36
373
4086
380
4194
0.63
4.66
102.8
23.0
93.68
91.45
fl
10.19
375
4125
335
3797
0.66
4.66
5.4
5.4
4.21
4.48
mmol/l
4.60
315
3494
85
536
1.70
4.48
7.9
6.9
1.32
1.25
mmol/l
0.06
67
441
13
28
4.74
4.39
1.4
1.1
—
—
—
0
0
12
24
5.09
4.34
1.3
1.0
—
—
—
0
0
15
38
4.04
4.33
2.9
1.2
—
—
—
0
0
152
1144
1.47
3.69
39.5
4.4
—
—
—
0
0
342
3810
0.69
3.69
7.1
5.5
6.04
6.06
mmol/l
0.09
320
3445
378
4130
0.67
3.62
80.7
20.4
80.68
81.98
umol/l
0.37
371
4063
20
80
2.56
3.59
1.2
1.2
—
—
—
0
0
113
1529
0.66
3.59
2.8
3.4
56.71
47.18
mg/l
0.20
84
997
324
3632
0.70
3.48
5.6
5.3
2.06
1.95
mu/l
0.58
303
3301
8
14
5.79
3.35
12.3
1.1
—
—
—
0
0
20
83
2.47
3.34
3.0
1.2
14.52
23.77
iu/l
1.03
15
71
13
38
3.48
3.33
1.5
1.2
—
—
—
0
0
6
7
8.65
3.27
1.5
1.3
—
—
—
0
0
13
39
3.39
3.24
1.5
1.2
0.40
0.40
g/l
—
8
33
118
1555
0.69
3.19
3.5
4.2
6.68
7.85
mg/mmol
0.17
79
991
121
1585
0.69
3.16
2.7
3.4
6.96
7.43
mmol/l
0.60
111
1341
13
40
3.31
3.16
1.3
2.1
—
—
—
0
0
316
2759
1.38
3.11
7.3
4.6
—
3.43
—
0
6
362
3958
0.70
3.09
50.9
14.1
—
—
—
0
0
23
106
2.23
3.07
6.7
5.0
1.31
1.70
mg/l
2.28
23
93
80
547
1.55
3.04
1.3
1.3
570.67
537.87
titre
0.06
15
141
374
4057
0.71
2.92
50.1
10.4
26.84
25.04
u/l
1.52
365
3896
59
381
1.62
2.86
3.2
2.4
0.67
0.35
e6/l
0.35
59
360
111
824
1.44
2.83
4.4
2.8
522.72
537.72
mosm/kgh2o
0.38
105
715
8
215
0.36
2.73
3.5
2.0
—
—
—
0
0
20
94
2.17
2.58
1.4
1.1
—
—
—
0
0
22
108
2.08
2.55
5.8
3.4
5.45
1.39
index
0.70
16
51
328
3606
0.75
2.52
5.8
4.5
1.53
1.26
mmol/l
7.48
307
3257
101
1318
0.71
2.48
3.7
3.5
—
—
—
0
0
208
1750
1.32
2.39
4.0
4.2
31.48
91.76
ng/l
1.03
168
1317
9
28
3.25
2.31
1.1
2.1
17.12
15.44
umol/l
—
9
23
10
34
2.98
2.29
1.2
1.1
—
—
—
0
0
10
34
2.98
2.29
1.1
1.1
—
—
—
0
0
21
386
0.52
2.26
1.6
1.6
—
—
—
0
0
7
18
3.93
2.26
12.6
3.1
0.71
1.06
index
—
7
18
29
165
1.80
2.24
1.2
1.3
—
—
—
0
0
376
4029
0.74
2.18
75.8
19.5
3.99
4.00
mmol/l
0.41
371
3932
278
2455
1.29
2.16
4.6
3.2
69.32
48.09
u/l
2.22
264
2268
377
4027
0.75
2.02
67.1
19.4
138.75
139.74
mmol/l
11.14
371
3937
8
26
3.11
2.02
1.4
1.3
—
—
—
0
0
10
38
2.66
2.01
1.1
1.2
—
—
—
0
0
9
32
2.84
2.01
2.4
2.2
—
—
—
0
0
56
390
1.49
1.99
9.6
8.2
—
—
—
0
0
169
1415
1.29
1.94
3.1
2.3
113.10
282.09
u/l
2.31
159
1322
7
22
3.21
1.88
1.3
1.0
—
—
—
0
0
28
167
1.72
1.88
1.3
1.2
—
—
—
0
0
11
46
2.42
1.86
1.2
1.2
3.17
4.74
u/ml
—
6
19
44
296
1.53
1.85
4.0
3.6
—
—
—
0
0
65
870
0.71
1.82
1.3
1.3
0.79
1.33
u/ml
1.09
16
240
16
80
2.03
1.82
2.4
1.7
421.64
16.58
u/ml
0.47
16
59
21
119
1.80
1.68
1.4
1.5
16957.21
12982.80
e6/l
0.24
14
81
11
49
2.27
1.64
2.5
1.1
—
—
—
0
0
11
49
2.27
1.64
2.5
1.1
—
—
—
0
0
36
240
1.54
1.60
5.0
3.2
24.47
25.31
mmol/l
0.66
36
233
21
122
1.75
1.57
1.3
1.2
—
—
—
0
0
275
3012
0.81
1.56
4.7
4.1
14.74
14.98
pmol/l
0.78
254
2722
6
21
2.88
1.51
1.3
1.1
—
—
—
0
0
194
1694
1.23
1.50
4.5
3.7
6.12
6.26
ph
1.08
116
935
12
58
2.09
1.50
2.1
3.1
—
—
—
0
0
9
38
2.39
1.46
4.6
2.0
3.89
100.68
u/ml
—
9
38
70
892
0.75
1.44
3.1
2.9
0.74
0.78
ug/l
0.19
43
597
6
22
2.75
1.44
1.0
1.2
112.83
135.55
nmol/l
—
6
22
120
997
1.27
1.43
1.7
1.8
120388797.15
21906369.76
pmol/l
0.38
103
808
18
293
0.60
1.33
1.2
1.2
—
—
—
0
0
6
131
0.45
1.30
2.5
2.0
74.83
41.93
nmol/l
—
6
123
10
49
2.06
1.22
1.5
1.2
2250.90
1778.81
e6/l
—
10
32
8
37
2.18
1.22
1.5
1.2
—
—
—
0
0
59
458
1.33
1.19
2.1
2.2
129.72
144.59
ug/g
0.16
47
355
0
33
0.00
1.16
0.0
1.6
—
—
—
0
0
7
140
0.49
1.10
10.4
10.1
—
—
—
0
0
14
81
1.75
1.10
1.1
1.4
—
—
—
0
0
19
121
1.59
1.07
3.0
3.7
0.87
0.85
nmol/l
0.06
12
102
14
228
0.60
1.06
1.2
1.4
—
—
—
0
0
7
33
2.14
1.06
13.0
2.9
16.86
12.11
index
—
7
18
5
22
2.28
1.03
1.2
1.5
—
—
—
0
0
5
107
0.46
1.02
2.8
2.1
186.20
231.35
pmol/l
—
5
100
20
131
1.55
1.01
2.2
1.8
—
—
—
0
0
18
115
1.59
1.01
5.2
4.5
—
—
—
0
0
9
49
1.85
0.99
1.2
1.2
—
—
—
0
0
0
30
0.00
0.97
0.0
1.5
—
1.27
—
0
23
0
31
0.00
0.96
0.0
1.5
—
—
—
0
0
234
2149
1.16
0.95
4.7
4.1
21.56
0.00
estimate
0.49
57
440
7
37
1.90
0.94
1.0
1.2
—
—
—
0
0
6
28
2.16
0.91
1.5
1.2
—
—
—
0
0
235
2172
1.15
0.85
4.7
4.1
0.02
0.01
estimate
0.14
51
426
229
2114
1.15
0.84
4.7
4.1
0.00
0.00
estimate
-0.00
55
429
8
48
1.68
0.79
1.3
1.2
—
—
—
0
0
20
140
1.45
0.78
1.4
1.5
1.29
1.14
g/l
1.03
20
134
6
34
1.77
0.76
1.8
1.2
—
—
—
0
0
6
34
1.77
0.76
1.0
1.4
—
—
—
0
0
6
107
0.56
0.73
2.0
1.4
—
—
—
0
0
7
40
1.76
0.71
1.0
1.6
14.87
16.36
%
—
7
40
7
40
1.76
0.71
1.1
1.2
—
—
—
0
0
9
57
1.59
0.71
1.6
1.2
36.69
24.89
g/l
—
9
50
52
429
1.24
0.70
2.3
2.6
3.96
7.56
ug/l
1.92
45
369
9
58
1.56
0.70
2.1
2.3
11.08
10.67
mmol/l
—
9
58
143
1556
0.89
0.57
4.4
4.4
1.88
2.08
ug/l
0.50
131
1386
41
339
1.23
0.57
1.9
1.5
—
—
—
0
0
33
266
1.26
0.57
1.2
1.4
—
—
—
0
0
5
88
0.56
0.56
2.2
1.4
—
—
—
0
0
124
1127
1.13
0.56
4.0
3.5
0.00
0.00
estimate
-0.00
40
338
9
62
1.46
0.53
3.9
2.2
1.19
1.19
mmol/l
—
9
62
9
64
1.41
0.51
3.9
2.2
3.83
4.07
mmol/l
—
9
64
9
64
1.41
0.51
3.9
2.2
106.33
105.30
mmol/l
—
9
64
6
41
1.47
0.50
1.0
1.6
7.15
7.95
mmol/l
—
6
41
27
331
0.81
0.47
2.7
2.7
5.86
6.03
ph
0.36
18
227
23
182
1.28
0.47
1.3
1.9
4.30
7.75
iu/ml
—
7
45
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
229.09
—
0
11
129
1201
1.10
0.39
4.4
4.2
0.00
0.00
estimate
-0.00
49
395
8
113
0.70
0.37
1.9
1.4
—
—
—
0
0
8
113
0.70
0.37
1.9
1.4
—
—
—
0
0
6
43
1.40
0.35
2.0
1.4
15.83
27.68
ng/l
—
6
43
33
382
0.85
0.34
5.0
2.0
0.00
0.04
estimate
—
5
75
19
154
1.24
0.34
1.2
1.2
—
0.22
—
0
13
94
1010
0.91
0.31
4.3
4.4
1.02
1.02
kg/l
0.13
80
659
16
129
1.25
0.30
1.1
1.2
—
826.00
—
0
5
94
876
1.09
0.29
3.0
2.2
2.44
2.45
mmol/l
0.17
84
762
60
547
1.11
0.29
1.3
1.2
—
—
—
0
0
45
405
1.12
0.27
1.3
1.3
—
—
—
0
0
8
66
1.22
0.27
1.8
3.0
40.54
10.13
pmol/l
—
8
66
13
105
1.24
0.25
1.4
1.3
260.00
315.58
ug/g
—
8
64
378
3843
0.94
0.24
80.5
15.3
34.40
25.44
mg/l
5.39
365
3144
72
670
1.09
0.24
1.2
1.3
1.27
11.49
u/ml
4.46
21
246
10
125
0.80
0.23
1.0
1.1
—
—
—
0
0
26
229
1.14
0.22
5.3
3.6
1.02
1.02
ratio
0.20
26
213
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
7.5
—
7.86
—
0
11
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
9
112
0.80
0.20
1.9
1.4
—
—
—
0
0
7
58
1.21
0.18
1.0
1.1
—
—
—
0
0
5
68
0.73
0.17
3.2
1.5
—
—
—
0
0
28
254
1.11
0.16
5.2
2.7
1.30
1.15
%
0.63
28
254
24
217
1.11
0.15
1.1
1.2
68.17
110.66
u/ml
—
6
87
25
227
1.11
0.14
2.7
2.5
—
—
—
0
0
9
109
0.82
0.13
1.8
1.4
—
—
—
0
0
16
179
0.89
0.12
1.1
1.2
—
—
—
0
0
27
250
1.08
0.11
2.9
2.7
0.71
0.63
%
1.07
27
250
165
1614
1.03
0.11
4.3
4.1
0.00
0.03
estimate
1.22
49
344
191
1890
1.02
0.05
3.0
2.5
75.66
78.08
nmol/l
0.60
177
1666
26
267
0.97
0.01
1.1
1.3
—
—
—
0
0
14
143
0.98
0.00
1.3
2.5
212.88
283.70
mg/l
—
8
53
73
727
1.00
0.00
1.2
1.3
17.85
32.82
iu/ml
2.56
26
224
0
8
0.00
0.00
0.0
1.0
—
30.61
—
0
8
0
8
0.00
0.00
0.0
3.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.7
—
20.24
—
0
8
0
7
0.00
-0.00
0.0
1.4
—
70.86
—
0
7
0
7
0.00
-0.00
0.0
1.3
—
0.61
—
0
7
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
10
100
1.00
-0.00
2.5
2.4
30.30
36.45
umol/l
—
10
89
6
67
0.89
-0.00
2.3
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.3
—
0.00
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
74.67
—
0
6
8
83
0.96
-0.00
1.8
1.7
324.38
306.50
mu/l
—
8
78
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
73.71
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
0.48
—
0
5

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: HLP_C3_AML – Acute myeloid leukaemia, helper endpoint

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).