Melanoma in situ of other and unspecified parts of face

CD2_INSITU_MELANOMA_FACE

melanoma: A malignant, usually aggressive tumor composed of atypical, neoplastic melanocytes. Most often, melanomas arise in the skin (cutaneous melanomas) and include the following histologic subtypes: superficial spreading melanoma, nodular melanoma, acral lentiginous melanoma, and lentigo maligna melanoma. Cutaneous melanomas may arise from acquired or congenital melanocytic or dysplastic nevi. Melanomas may also arise in other anatomic sites including the gastrointestinal system, eye, urinary tract, and reproductive system. Melanomas frequently metastasize to lymph nodes, liver, lungs, and brain.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

483

4. Check minimum number of events

None

483

5. Include endpoints

None

483

6. Filter based on genotype QC (FinnGen only)

439

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 439 231 208
Unadjusted period prevalence (%) 0.09 0.08 0.10
Median age at first event (years) 73.39 72.04 74.89

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
452
Matched controls
4520
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D03.31
ICD-10 Finland
Melanoma in situ in another or unspecified part of the face
+∞
307.7
440
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
44.3
307.7
354
341
8742/2-C44.9
ICD-O-3
Lentigo maligna of skin, NOS
299.6
132.7
129
6
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
9.9
125.5
196
324
ZZR00
NOMESCO Finland
Flap of skin
20.8
122.9
100
61
L57.0
ICD-10 Finland
Actinic keratosis
7.1
94.2
209
486
D22.3
ICD-10 Finland
Melanocytic naevi of other and unspecified parts of face
23.1
91.4
69
35
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
8.5
84.6
132
210
L81.4
ICD-10 Finland
Other melanin hyperpigmentation
38.2
81.3
51
15
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
11.8
68.3
75
75
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
11.2
65.8
75
79
R23.8
ICD-10 Finland
Other and unspecified skin changes
5.1
64.9
225
737
TQW99
NOMESCO Finland
Other minor procedure on skin
7.2
57.7
98
167
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
5.6
53.4
123
281
C43.31
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face originating in lentigo maligna
174.4
45.7
47
*
D03.30
ICD-10 Finland
Melanoma in situ on the lip
+∞
42.4
40
*
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
5.5
41.3
91
197
S18
ICPC
Laceration/cut
4.1
40.4
337
1877
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
6.9
40.0
67
111
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
8.9
33.0
43
53
ZXC50
NOMESCO Finland
Cryotherapy
6.5
32.7
57
98
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
7.0
31.5
51
81
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
7.4
28.5
43
63
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
6.0
28.1
53
98
8720/2-C44.9
ICD-O-3
Melanoma in situ of skin, NOS
66.4
27.3
31
5
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
5.6
25.4
51
100
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
3.9
25.2
85
253
L82
ICD-10 Finland
Seborrhoeic keratosis
3.0
24.9
151
648
D06BB10
ATC
imiquimod; topical
4.5
23.8
64
161
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
7.3
21.9
33
48
SPAT1153
SPAT
Removal of sutures
2.5
20.5
221
1244
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
4.8
18.9
45
102
S82
ICPC
Naevus/mole
2.9
18.9
104
416
8742/3-C44.9
ICD-O-3
Lentigo maligna melanoma of skin, NOS
104.4
18.7
20
*
TQW40, ,
SPAT
3.2
18.3
81
285
ZXC20
NOMESCO Finland
Use of chemical agents
5.7
18.1
35
66
ZZA50
NOMESCO Finland
Full thickness skin graft
19.0
18.0
27
15
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
5.8
17.9
34
63
DHB00
NOMESCO Finland
Excision of lesion of external nose
13.9
17.7
30
23
WX110
NOMESCO Finland
Infiltration anesthesia
2.6
17.1
342
2465
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
4.9
16.4
37
80
C43.39
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face other or unspecified histology
49.4
16.1
19
*
ZZA00
NOMESCO Finland
Split skin graft
5.0
15.7
35
75
8742/2-C44.3
ICD-O-3
Lentigo maligna of skin of other and unspecified parts of face
165.5
15.6
16
*
ZXC15
NOMESCO Finland
Use of photodynamic technique
6.4
14.8
25
41
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
5.4
14.8
30
59
QXE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in uspecified region
16.1
14.6
23
15
D22
ICD-10 Finland
Melanocytic naevi
4.7
14.3
34
77
S21
ICPC
Skin texture symptom/complaint
2.5
14.1
106
491
8720/3-C44.3
ICD-O-3
Malignant melanoma, NOS, of skin of other and unspecified parts of face
41.4
13.2
16
*
C43.52
ICD-10 Finland
Malignant melanoma on the torso: 'superficial spreading' type
11.5
13.2
24
22
Z2221
NOMESCO Finland
Medical doctor
2.2
12.9
158
898
D03.4
ICD-10 Finland
Melanoma in situ of scalp and neck
+∞
12.6
12
*
S29
ICPC
Skin symptom/complaint other
2.2
12.2
131
705
8720/3-C44.9
ICD-O-3
Malignant melanoma, NOS, of skin, NOS
11.5
12.2
22
20
S26
ICPC
Fear of cancer of skin
6.1
11.9
21
36
I78.1
ICD-10 Finland
Naevus, non-neoplastic
5.0
11.8
26
55
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
5.0
11.8
26
55
J01DB01
ATC
cefalexin; oral
2.6
11.4
388
3179
D03.9
ICD-10 Finland
Melanoma in situ, unspecified
36.0
11.3
14
*
S77
ICPC
Malignant neoplasm of skin
8.4
11.2
24
30
F16
ICPC
Eyelid symptom/complaint
3.5
10.9
38
114
D03.5
ICD-10 Finland
Melanoma in situ of trunk
18.4
10.8
16
9
XQ845
NOMESCO Finland
Dermatoscopy
4.8
10.6
24
52
C43.32
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face 'superficial spreading' type
24.0
10.3
14
6
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
5.0
10.1
22
46
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
4.3
10.0
26
63
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
4.7
9.9
23
51
C43
ICD-10 Finland
Malignant melanoma of skin
26.7
9.9
13
5
D22.4
ICD-10 Finland
Melanocytic naevi of scalp and neck
9.9
9.9
19
20
D04.6
ICD-10 Finland
Carcinoma in situ: Skin of upper limb, including shoulder
9.9
9.9
19
20
XQ848
NOMESCO Finland
Dermatological photography
4.0
9.6
28
74
C43.30
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face without histology
30.7
9.4
12
*
D03.1
ICD-10 Finland
Melanoma in situ of eyelid, including canthus
+∞
9.4
9
*
C44.61
ICD-10 Finland
Basocellular carcinoma of the skin of the upper extremity including the shoulder
7.5
9.3
21
29
A98
ICPC
Health maint/preventive medicine
4.4
9.2
436
3890
PJA12
NOMESCO Finland
Sentinel node biopsy
2.6
9.2
57
239
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.8
8.9
246
1790
WX002
NOMESCO Finland
Sedation and analgesia
2.0
8.8
122
711
D22.7
ICD-10 Finland
Melanocytic naevi of lower limb, including hip
7.4
8.8
20
28
Z01.2
ICD-10 Finland
Dental examination
1.8
8.8
196
1333
8742/3-C44.3
ICD-O-3
Lentigo maligna melanoma of skin of other and unspecified parts of face
91.7
8.4
9
*
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
13.1
8.4
14
11
B07.9
ICD-10 Finland
Verruca simplex
4.0
8.4
24
63
A97
ICPC
No disease
1.9
8.0
115
676
TQW40
NOMESCO Finland
Remowal of suture of skin
2.6
7.9
46
187
D04.5
ICD-10 Finland
Carcinoma in situ: Skin of trunk
7.6
7.7
17
23
ZXE00
NOMESCO Finland
One hour or less
1.8
7.6
191
1332
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
7.4
132
830
D04.7
ICD-10 Finland
Carcinoma in situ: Skin of lower limb, including hip
8.6
7.4
15
18
C08CA13
ATC
lercanidipine; oral
1.9
7.3
99
570
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
4.1
7.2
20
51
SPAT1141
SPAT
Excision of skin or mucous membrane lesion
3.0
7.2
32
112
QAA50
NOMESCO Finland
Cryotherapy of skin of head or neck
8.1
7.2
15
19
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
5.8
7.1
19
34
ZQZ00
NOMESCO Finland
Treatment of several skin areas
10.3
7.1
13
13
E0000UV, ,
ATC
1.7
7.0
201
1444
QAE99, ,
SPAT
7.7
6.9
15
20
TQW80
NOMESCO Finland
Local dermatologic skincare
3.7
6.8
21
58
XQ846
NOMESCO Finland
Digital dermatoscopy and registration of nevi
40.7
6.8
8
*
C44.71
ICD-10 Finland
Basocellular carcinoma of the skin of the lower extremity including the hip
6.0
6.7
17
29
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.9
6.6
103
618
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
1.9
6.4
88
507
H01.0
ICD-10 Finland
Blepharitis
2.7
6.4
34
132
QAB10
NOMESCO Finland
Major dressing of wound of skin of head or neck
6.1
6.4
16
27
C44.21
ICD-10 Finland
Basocellular carcinoma of the skin of the outer ear and the outer ear canal
5.2
6.2
18
36
D03.6
ICD-10 Finland
Melanoma in situ of upper limb, including shoulder
27.1
6.2
8
*
K95
ICPC
Varicose veins of leg
4.1
6.2
17
43
C43.50
ICD-10 Finland
Malignant melanoma of the torso without histology
12.7
6.1
10
8
R4110
NOMESCO Finland
Physiotherapy
1.7
6.1
147
1001
L01BC02
ATC
fluorouracil; systemic, topical
8.8
6.1
12
14
L03
ICPC
Low back symptom/complaint
1.7
6.0
137
918

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
242
570
7.99
110.19
1.9
1.4
—
—
—
0
0
370
1660
7.77
76.20
4.6
2.4
—
—
—
0
0
134
411
4.21
39.39
1.5
1.5
—
—
—
0
0
80
204
4.55
29.43
1.4
1.3
—
—
—
0
0
443
3968
6.85
13.77
35.9
30.9
6.70
6.87
e9/l
1.02
429
3863
431
3750
4.21
10.98
22.5
20.4
23.86
26.65
mg/l
0.92
362
3212
175
1115
1.93
9.92
5.6
4.3
84.03
85.37
%
0.30
168
1099
215
1468
1.89
9.84
7.9
5.8
—
—
—
0
0
438
3898
4.99
9.80
16.5
13.8
22.89
23.45
u/l
0.49
419
3764
441
3947
5.82
9.73
31.1
27.9
85.28
82.88
umol/l
0.47
433
3901
419
3634
3.10
9.70
6.1
5.5
1.51
1.48
mmol/l
0.73
375
3258
427
3744
3.54
9.67
7.3
6.6
2.51
2.48
mmol/l
0.32
387
3379
442
3967
6.16
9.62
35.9
30.8
91.95
91.88
fl
0.11
434
3913
442
3968
6.15
9.59
36.2
30.9
239.26
241.74
e9/l
0.34
429
3882
442
3968
6.15
9.59
37.0
31.6
39.73
39.28
%
0.96
434
3914
442
3968
6.15
9.59
36.0
30.9
4.40
4.36
e12/l
0.71
427
3861
442
3968
6.15
9.59
35.9
30.8
30.47
30.43
pg
0.20
434
3914
442
3968
6.15
9.59
36.2
31.1
132.43
131.45
g/l
0.67
434
3913
420
3653
3.12
9.55
6.2
5.6
4.42
4.40
mmol/l
0.09
377
3307
439
3923
5.14
9.55
28.5
25.3
139.48
139.55
mmol/l
0.22
431
3849
439
3926
5.11
9.47
29.2
25.5
3.98
4.01
mmol/l
0.95
432
3846
410
3548
2.67
8.93
6.3
5.6
1.89
2.04
mu/l
2.02
363
3186
422
3711
3.07
8.78
6.5
5.9
6.00
6.11
mmol/l
1.14
376
3322
190
1283
1.83
8.72
4.3
3.6
—
0.00
estimate
—
0
6
265
1980
1.82
8.67
8.2
6.1
0.67
0.65
%
0.20
229
1845
404
3483
2.51
8.67
4.9
4.7
1.22
1.24
mmol/l
0.32
357
3092
264
1983
1.80
8.36
8.1
6.0
2.65
2.85
%
0.70
228
1843
264
1984
1.79
8.34
8.2
6.1
9.11
9.10
%
0.02
229
1848
424
3781
2.96
7.75
20.2
18.3
—
—
—
0
0
414
3651
2.59
7.71
7.8
7.6
39.43
40.53
mmol/mol
1.93
379
3363
262
2003
1.73
7.44
8.2
6.1
27.39
25.75
%
1.40
231
1886
194
1367
1.73
7.38
4.4
3.6
0.51
0.56
e6/l
0.08
151
1026
167
1150
1.72
6.77
2.9
3.0
353.94
354.84
umol/l
0.04
133
979
214
1588
1.66
6.47
2.4
2.0
1.31
1.24
mmol/l
0.60
160
1285
200
1466
1.65
6.29
2.7
2.5
—
—
—
0
0
272
2155
1.66
6.29
8.1
5.8
0.04
0.04
e9/l
0.59
211
1836
254
1980
1.65
6.24
8.1
6.0
58.06
58.68
%
0.34
232
1878
124
802
1.75
6.20
4.3
3.4
2.58
2.27
e6/l
0.13
64
415
277
2214
1.65
6.10
8.4
6.0
0.18
0.19
e9/l
1.20
218
1908
273
2176
1.64
6.06
8.1
5.9
1.80
1.83
e9/l
0.11
215
1901
238
1837
1.62
5.99
17.1
13.1
0.00
0.00
e9/l
0.87
185
1516
293
2383
1.65
5.95
10.7
9.7
3.93
4.28
e9/l
1.88
236
2075
269
2147
1.62
5.85
8.1
5.8
0.58
0.62
e9/l
1.36
207
1824
226
1735
1.61
5.73
5.5
4.5
80.71
100.14
e6/l
0.19
167
1271
278
2249
1.61
5.61
8.2
6.7
1.22
1.21
mmol/l
1.24
258
2062
249
1988
1.56
5.12
3.3
2.9
—
—
estimate
—
0
0
367
3217
1.75
5.11
10.3
8.8
79.06
81.06
u/l
0.31
339
3036
297
2476
1.58
4.99
8.3
7.5
1.22
1.21
mmol/l
1.45
251
2142
61
338
1.93
4.96
5.0
4.5
—
—
—
0
0
206
1584
1.55
4.96
4.4
3.8
94.94
103.43
e6/l
0.06
163
1242
194
1477
1.55
4.85
7.1
6.3
2.93
4.17
ug/l
0.71
163
1311
154
1117
1.57
4.75
2.7
2.5
—
—
—
0
0
344
2985
1.64
4.74
4.8
4.3
15.00
15.18
pmol/l
0.69
295
2670
124
868
1.59
4.41
4.0
3.5
0.84
0.81
ug/l
0.09
96
626
78
489
1.72
4.25
2.8
3.1
65.08
65.79
g/l
0.32
70
444
240
1957
1.48
4.11
2.4
2.5
82.73
80.54
nmol/l
0.58
204
1718
21
81
2.67
4.03
1.7
2.4
33.57
31.73
pg
1.76
21
81
68
419
1.73
3.94
2.6
2.5
28.93
35.18
u/l
1.14
57
341
208
1667
1.46
3.79
3.4
3.7
2.35
2.35
mmol/l
0.09
186
1499
258
2155
1.46
3.78
2.4
2.3
97.87
94.71
pmol/l
0.46
132
1107
40
211
1.98
3.77
1.2
1.4
52.86
52.33
au/ml
—
5
20
168
1298
1.47
3.67
6.6
6.6
—
—
—
0
0
41
223
1.92
3.55
3.0
3.0
—
—
—
0
0
256
2151
1.44
3.53
5.6
5.0
35.34
34.75
g/l
0.83
233
2015
194
1550
1.44
3.52
6.8
4.3
7.40
7.40
ph
0.46
145
1114
55
332
1.75
3.43
1.7
1.6
—
—
—
0
0
36
192
1.95
3.31
3.4
3.9
1.27
3.18
ratio
2.16
18
106
13
43
3.08
3.27
1.2
1.3
21.02
30.11
ng/l
0.50
13
43
130
976
1.47
3.23
2.9
3.3
523.28
530.74
mosm/kgh2o
0.18
120
860
191
1549
1.40
3.08
1.7
1.8
19.06
20.70
nmol/l
0.81
152
1287
37
206
1.87
3.01
3.6
4.2
58.02
57.82
mg/l
0.00
28
178
37
206
1.87
3.01
3.6
4.2
58.40
85.76
mg/l
0.40
28
176
21
94
2.29
3.01
2.3
2.6
0.87
0.90
%
0.08
15
69
94
670
1.51
3.00
1.3
1.3
24.83
40.78
iu/ml
0.98
21
219
0
78
0.00
2.98
0.0
2.3
—
10.44
—
0
78
77
526
1.56
2.98
2.2
1.8
—
—
—
0
0
69
993
0.64
2.95
4.6
4.9
1.02
1.02
kg/l
0.05
50
686
185
1501
1.39
2.94
2.0
2.2
192.37
211.02
u/l
0.15
174
1418
265
2286
1.38
2.89
4.1
3.3
41.94
53.02
u/l
2.81
233
2102
60
389
1.63
2.89
3.8
4.2
1.13
0.55
%
0.48
12
137
204
1696
1.37
2.75
4.2
4.1
—
0.75
—
0
8
38
220
1.79
2.75
2.2
2.7
10.36
10.14
g/l
0.11
30
196
77
537
1.52
2.71
2.6
2.8
70.36
70.02
e9/l
0.03
50
413
10
30
3.38
2.61
1.2
1.3
—
—
—
0
0
78
552
1.50
2.57
1.4
1.5
—
—
—
0
0
58
385
1.58
2.54
4.0
4.3
0.00
0.10
%
—
8
121
17
349
0.47
2.54
5.4
6.0
25.68
24.50
mmol/l
0.57
17
340
60
403
1.56
2.51
3.9
4.6
0.00
0.17
%
1.25
11
119
92
678
1.45
2.47
2.5
2.6
1.74
1.84
%
0.48
79
615
136
1075
1.38
2.46
3.2
3.1
2.44
2.47
mmol/l
1.90
123
968
29
162
1.84
2.37
1.2
1.2
—
—
—
0
0
74
528
1.48
2.34
1.6
1.3
—
—
—
0
0
70
494
1.49
2.34
4.5
2.8
6.78
8.48
umol/l
0.73
61
441
60
410
1.53
2.33
1.9
1.5
—
—
—
0
0
13
53
2.50
2.29
1.0
1.2
—
—
nmol/l
—
0
0
125
985
1.37
2.28
1.5
1.3
—
—
—
0
0
11
254
0.42
2.24
3.2
4.1
1.61
1.47
%
0.41
11
245
318
2883
1.35
2.20
5.5
5.0
—
0.25
—
0
8
10
36
2.82
2.15
1.1
1.1
—
—
—
0
0
59
410
1.50
2.13
4.0
4.2
0.41
0.90
%
1.77
11
145
59
412
1.50
2.08
3.3
2.6
—
—
—
0
0
214
1848
1.30
2.04
3.8
3.1
158.25
143.83
ug/l
0.31
186
1683
265
2357
1.30
2.01
7.0
6.9
11.84
12.11
umol/l
0.17
248
2256
204
1767
1.28
1.85
3.2
3.4
2338.51
1536.89
ng/l
0.51
177
1553
13
60
2.20
1.79
1.1
1.3
—
—
—
0
0
63
461
1.43
1.77
11.4
9.0
—
—
—
0
0
62
453
1.43
1.76
3.5
4.4
7.37
7.35
ph
1.09
40
316
38
251
1.56
1.75
2.3
2.2
14.44
12.29
nmol/l
0.70
31
215
80
612
1.37
1.74
1.3
1.3
—
—
—
0
0
57
411
1.44
1.74
5.1
3.7
92.78
86.82
ng/l
0.25
51
352
37
244
1.56
1.72
1.2
1.3
—
—
—
0
0
13
62
2.13
1.67
3.7
2.7
3.53
4.71
e9/l
1.28
13
62
11
49
2.28
1.65
2.7
1.9
1.74
1.44
mmol/l
0.10
11
49
168
1440
1.27
1.61
5.7
4.5
—
—
—
0
0
13
63
2.09
1.61
1.4
1.1
246.25
320.67
u/ml
—
8
30
12
233
0.50
1.59
3.8
4.2
1.07
0.86
%
0.83
12
223
12
57
2.14
1.56
1.2
1.9
0.42
0.98
g/l
—
7
51
8
33
2.45
1.54
2.0
2.2
1.99
2.02
ug/l
—
8
28
0
43
0.00
1.53
0.0
3.3
—
8.19
—
0
43
5
15
3.36
1.52
1.0
1.1
—
—
—
0
0
183
1595
1.25
1.50
4.2
3.4
6.50
6.89
mmol/l
0.67
145
1324
9
37
2.46
1.48
1.1
1.1
—
—
—
0
0
16
87
1.87
1.47
1.6
1.5
—
—
—
0
0
135
1138
1.27
1.47
2.8
2.9
3.72
5.16
e6/l
1.15
128
1042
9
38
2.40
1.46
1.2
1.1
—
—
—
0
0
11
52
2.14
1.45
1.5
1.1
—
—
—
0
0
5
16
3.15
1.44
1.0
1.1
—
—
—
0
0
92
741
1.30
1.43
2.7
1.6
2.76
2.69
g/l
0.07
47
403
22
134
1.67
1.42
1.4
1.3
1.20
1.15
g/l
0.33
22
129
77
606
1.33
1.41
1.3
1.3
17.84
15.72
u/ml
0.05
18
216
47
341
1.42
1.41
2.1
1.4
—
—
—
0
0
15
82
1.86
1.37
1.4
1.2
—
—
—
0
0
181
1589
1.23
1.36
4.2
3.5
37.44
48.50
mg/l
0.31
114
1009
5
17
2.96
1.36
1.0
1.1
—
—
—
0
0
18
106
1.73
1.31
1.1
1.1
—
—
—
0
0
5
18
2.80
1.29
1.2
1.1
107.20
142.17
nmol/l
—
5
18
97
799
1.27
1.27
2.5
3.3
0.81
0.82
mmol/l
0.33
90
753
6
25
2.42
1.24
1.0
1.6
—
—
—
0
0
102
849
1.26
1.23
1.3
1.2
1.04
1.45
u/ml
0.34
21
200
94
775
1.27
1.22
4.1
2.6
22.34
21.42
%
0.32
85
723
17
101
1.71
1.21
2.9
4.2
—
—
—
0
0
34
470
0.70
1.19
2.0
2.6
7.50
7.32
ug/l
0.02
29
409
38
277
1.41
1.14
3.3
1.9
1.47
1.55
g/l
0.18
33
254
183
1634
1.20
1.12
5.2
4.2
7.22
8.34
mg/mmol
0.16
109
1004
7
136
0.51
1.11
4.4
5.4
1.11
1.22
mmol/l
—
7
124
64
513
1.29
1.05
1.9
3.0
4.77
4.89
e9/l
0.04
47
429
285
2660
1.19
1.04
6.0
5.5
6.57
6.84
mmol/l
2.24
276
2544
32
231
1.41
1.03
1.6
1.4
—
—
—
0
0
240
2208
1.19
1.03
4.6
4.6
0.00
0.00
estimate
-0.00
58
482
121
1049
1.21
1.00
4.2
4.3
—
0.18
—
0
17
50
391
1.31
0.99
2.2
1.5
—
—
—
0
0
5
23
2.19
0.98
4.2
1.0
36.60
74.76
mg/l
—
5
17
12
69
1.76
0.97
1.3
1.3
70443.00
137692.54
e6/l
—
6
37
13
77
1.71
0.96
1.2
1.7
—
—
—
0
0
147
1646
0.84
0.95
4.9
4.7
0.06
0.05
estimate
0.05
49
405
7
37
1.91
0.94
2.0
2.8
—
—
—
0
0
42
323
1.33
0.94
5.5
3.6
24.86
24.35
mmol/l
0.61
42
318
111
961
1.21
0.93
2.1
1.7
1.45
1.50
mg/l
0.06
92
768
63
765
0.79
0.92
9.9
6.9
104.30
104.11
mmol/l
0.11
63
765
37
281
1.34
0.90
1.2
1.2
—
—
—
0
0
10
56
1.80
0.88
1.3
1.2
—
—
—
0
0
95
815
1.21
0.88
4.0
2.6
2.18
2.25
g/l
0.75
85
752
111
967
1.20
0.87
1.8
1.8
1208.81
1197.81
nmol/l
0.03
69
736
6
30
2.01
0.87
1.2
1.9
—
—
—
0
0
14
88
1.61
0.85
1.1
1.2
—
—
—
0
0
17
113
1.52
0.83
1.5
1.3
—
—
—
0
0
6
32
1.89
0.82
1.0
1.1
—
—
—
0
0
240
2235
1.16
0.82
4.7
4.6
0.00
3.25
estimate
0.50
58
500
59
486
1.25
0.80
3.0
2.2
0.22
0.20
g/l
1.16
54
449
242
2258
1.15
0.79
4.8
4.6
0.00
0.65
estimate
0.51
52
466
0
26
0.00
0.78
0.0
1.8
—
0.95
—
0
18
251
2352
1.15
0.77
20.0
17.8
1.31
1.32
inr
0.13
203
1963
94
817
1.19
0.76
6.1
5.1
—
—
—
0
0
10
59
1.71
0.76
1.2
2.5
—
—
—
0
0
35
272
1.31
0.75
2.9
2.6
—
—
—
0
0
5
24
2.10
0.74
1.0
1.6
42.14
42.27
%
—
5
24
60
502
1.23
0.72
1.5
1.3
342.86
480.00
titre
0.64
14
118
24
177
1.38
0.72
1.6
1.2
126.47
113.00
u/ml
—
7
64
116
1032
1.17
0.72
1.9
1.8
110112822.34
14165088.95
pmol/l
0.41
89
826
27
205
1.34
0.69
2.7
2.5
0.00
0.02
estimate
—
6
58
7
117
0.59
0.69
1.7
3.6
87.29
2482.28
u/ml
—
7
110
5
92
0.54
0.67
1.4
1.4
—
—
—
0
0
26
197
1.34
0.67
3.1
3.1
4.11
4.28
pmol/l
0.42
21
173
18
128
1.42
0.66
1.8
1.5
11627.57
21755.10
e6/l
—
7
92
191
1770
1.14
0.66
3.9
4.1
6.13
6.27
ph
0.84
82
946
204
1899
1.14
0.66
4.5
4.4
33.09
40.59
ng/l
0.67
164
1549
175
1613
1.14
0.66
3.3
3.6
—
—
—
0
0
10
62
1.63
0.65
1.6
1.4
—
—
—
0
0
98
868
1.16
0.64
4.0
2.6
12.01
12.01
umol/l
0.00
90
803
18
129
1.41
0.64
1.5
1.3
0.24
0.23
g/l
0.16
18
124
5
29
1.73
0.64
1.0
1.1
—
—
—
0
0
13
87
1.51
0.64
3.9
2.8
60.15
59.79
%
0.04
13
87
53
445
1.22
0.63
2.1
2.2
109.67
160.27
ug/g
0.83
39
342
11
71
1.56
0.62
1.2
1.2
—
—
—
0
0
6
35
1.72
0.58
1.8
1.1
—
—
—
0
0
121
1099
1.14
0.57
4.2
3.9
—
—
—
0
0
6
36
1.68
0.57
1.0
1.3
91.67
90.64
pmol/l
—
6
36
11
73
1.52
0.56
1.3
1.4
—
—
—
0
0
27
338
0.79
0.55
2.8
4.0
—
—
—
0
0
41
345
1.21
0.50
12.0
9.5
24.16
24.50
mmol/l
0.39
41
339
47
545
0.85
0.47
11.4
8.1
119.36
119.54
g/l
0.02
47
539
138
1280
1.11
0.46
4.1
2.9
73.46
33.26
u/l
0.48
128
1205
7
50
1.41
0.45
1.7
1.3
—
—
—
0
0
29
239
1.23
0.44
3.2
3.9
—
—
—
0
0
9
131
0.68
0.43
1.1
1.3
—
—
—
0
0
14
104
1.36
0.43
1.1
1.3
—
—
—
0
0
10
70
1.44
0.42
1.2
1.1
—
—
—
0
0
13
96
1.36
0.42
1.4
1.4
35.52
29.74
g/l
0.84
13
87
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.4
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
58
649
0.88
0.38
9.9
7.5
12.09
11.69
kpa
0.31
58
631
58
649
0.88
0.38
9.9
7.5
5.20
5.13
kpa
0.22
58
631
12
89
1.36
0.38
1.2
1.2
10.43
12.01
e6/l
—
7
67
27
225
1.21
0.38
1.5
2.0
—
—
—
0
0
13
98
1.34
0.38
1.2
1.6
—
—
—
0
0
58
648
0.88
0.37
9.7
7.5
7.43
7.42
ph
1.20
23
384
140
1314
1.09
0.37
2.4
2.4
2.86
3.03
mg/l
0.42
114
1134
39
338
1.17
0.37
3.2
3.7
7.43
7.42
ph
0.31
30
284
9
70
1.29
0.37
1.3
1.1
—
—
—
0
0
6
42
1.43
0.35
1.2
1.2
—
—
—
0
0
12
91
1.33
0.34
1.2
1.3
0.43
1462.72
e6/l
—
7
71
16
127
1.27
0.34
1.2
1.2
—
—
—
0
0
47
417
1.14
0.33
2.3
2.3
0.00
0.04
estimate
—
10
75
58
642
0.89
0.33
9.7
7.5
0.56
1.12
mmol/l
0.52
50
536
52
579
0.88
0.33
10.6
7.8
96.34
95.22
%
1.68
52
568
6
47
1.28
0.32
1.2
1.4
0.92
0.86
g/l
—
6
47
13
102
1.28
0.30
4.2
2.3
27.31
33.58
umol/l
0.84
13
88
12
93
1.30
0.30
4.3
4.7
2.87
2.60
mmol/l
—
7
59
54
489
1.12
0.29
10.0
7.7
1.30
1.34
mmol/l
0.13
54
479
13
104
1.26
0.26
1.0
1.1
—
—
—
0
0
8
67
1.20
0.26
1.1
1.3
—
—
—
0
0
16
134
1.20
0.23
3.7
3.4
1.10
1.88
index
—
10
73
62
575
1.09
0.22
4.1
4.4
4.36
27.66
ug/l
1.07
49
493
15
125
1.21
0.22
2.6
1.3
0.10
0.35
mg/l
—
6
51
7
95
0.73
0.22
3.7
5.5
12.00
11.30
mmol/l
—
7
90
7
95
0.73
0.22
3.7
5.5
104.00
105.00
mmol/l
—
7
90
5
41
1.22
0.22
2.6
3.3
14.84
16.20
%
—
5
41
5
42
1.19
0.21
1.0
1.4
1.84
1.59
g/l
—
5
42
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
7.95
—
0
10
0
12
0.00
0.21
0.0
1.2
—
170.32
—
0
12
0
12
0.00
0.21
0.0
4.4
—
49.00
—
0
12
10
123
0.81
0.20
10.3
14.1
—
—
—
0
0
6
48
1.25
0.20
1.2
2.8
521.83
719.54
mg
—
6
48
6
50
1.20
0.20
1.8
1.6
—
—
—
0
0
6
51
1.18
0.19
1.3
1.1
—
—
—
0
0
6
51
1.18
0.19
2.8
2.9
—
—
—
0
0
7
59
1.19
0.18
1.0
1.0
—
—
—
0
0
7
60
1.17
0.18
1.0
1.3
—
—
—
0
0
7
60
1.17
0.18
1.0
1.3
—
—
—
0
0
7
60
1.17
0.18
1.0
1.3
—
—
—
0
0
7
60
1.17
0.18
1.0
1.3
—
—
—
0
0
147
1421
1.05
0.17
2.7
2.5
64.16
120.09
u/l
0.49
131
1316
41
443
0.92
0.17
2.2
3.3
295.62
240.16
ng/l
0.21
34
408
120
1155
1.05
0.16
4.3
4.2
0.02
0.07
estimate
0.30
46
379
8
71
1.13
0.16
1.0
1.2
—
—
—
0
0
293
2883
1.05
0.16
31.9
27.6
330.45
330.55
g/l
0.07
293
2872
9
80
1.13
0.15
2.3
3.0
—
—
—
0
0
15
132
1.14
0.13
1.6
1.5
—
—
—
0
0
10
85
1.18
0.12
1.2
1.2
3.67
3.84
mmol/l
—
10
79
101
976
1.04
0.12
4.0
4.5
93.37
328.48
ng/l
2.29
90
856
132
1284
1.04
0.12
4.8
4.7
0.00
0.00
estimate
0.50
54
434
25
232
1.08
0.10
1.6
1.7
1.56
3.04
ug/l
0.44
19
199
5
44
1.14
0.10
1.0
1.0
563.40
564.73
ng/l
—
5
26
5
44
1.14
0.10
1.0
1.0
217.00
294.28
ng/l
—
5
25
6
56
1.07
0.08
1.2
1.1
—
—
—
0
0
6
58
1.03
0.08
1.0
1.0
—
—
—
0
0
75
728
1.04
0.08
2.5
2.0
—
—
—
0
0
33
347
0.95
0.07
3.4
3.2
6.24
6.12
ph
0.36
19
265
59
571
1.04
0.07
4.5
3.5
7.37
7.38
ph
1.40
33
335
8
93
0.86
0.07
10.9
2.8
11.36
9.76
pmol/l
—
8
93
15
138
1.09
0.06
1.3
1.4
255.46
274.84
ug/g
—
7
81
18
169
1.07
0.05
2.1
2.8
147.29
226.53
mg/l
—
7
62
11
101
1.09
0.04
1.3
1.3
490.82
492.88
mg/l
0.01
11
95
21
200
1.05
0.04
1.3
1.3
—
—
—
0
0
31
303
1.02
0.01
12.9
9.0
16.10
15.66
%
0.43
31
296
10
102
0.98
0.00
1.2
1.1
—
—
—
0
0
36
359
1.00
0.00
1.8
1.5
—
—
—
0
0
5
51
0.98
0.00
2.4
1.5
10.92
10.40
%
—
5
51
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
2.4
—
2.86
—
0
7
5
51
0.98
0.00
3.0
4.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
0.02
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
64
0.94
-0.00
2.2
1.5
—
—
—
0
0
7
77
0.91
-0.00
3.1
2.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
7
72
0.97
-0.00
7.0
5.0
10.56
12.07
mg/l
—
7
67
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
59
0.85
-0.00
1.4
2.2
90.70
89.02
%
—
5
59
0
8
0.00
-0.00
0.0
2.5
—
2327.88
—
0
8
0
5
0.00
-0.00
0.0
1.6
—
76.00
—
0
5
0
6
0.00
-0.00
0.0
2.0
—
0.48
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_INSITU_MELANOMA_FACE – Melanoma in situ of other and unspecified parts of face

GWS hits: 1

This endpoint is excluded from FinRegistry analyses (omitted endpoint).