Spinal enthesopathy

M13_SPINENTHES

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M46.0
  • Hospital discharge: ICD-8 7131
  • Cause of death: ICD-10 M46.0
  • Cause of death: ICD-8 7131

2 out of 7 registries used, show all original rules.

1666

4. Check minimum number of events

None

1666

5. Include endpoints

None

1666

6. Filter based on genotype QC (FinnGen only)

1467

Control definitions (FinnGen only)

Control exclude
M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
M46
Name in latin
Enthesopathia spinalis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 33053 17098 15067
Only index persons 13197 8115 5082
Unadjusted period prevalence (%)
Whole population 0.47 0.49 0.42
Only index persons 0.26 0.30 0.19
Median age at first event (years)
Whole population 55.76 56.06 55.36
Only index persons 50.71 51.48 49.49

-FinnGen-

Key figures

All Female Male
Number of individuals 1467 585 882
Unadjusted period prevalence (%) 0.33 0.21 0.40
Median age at first event (years) 49.77 48.45 50.64

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1502
Matched controls
14993
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M48.0
ICD-10 Finland
Spinal stenosis
52.9
307.7
241
54
71312
ICD-8 Finland
Osteo-arthritis and allied conditions, Spondylarthritis lumbalis sive lumbosacralis
+∞
307.7
634
*
71310
ICD-8 Finland
Osteo-arthritis and allied conditions, Spondylarthritis cervicalis
+∞
307.7
646
*
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
39.1
245.2
152
43
M46.0
ICD-10 Finland
Spinal enthesopathy
+∞
235.6
220
*
72870
ICD-8 Finland
Vertebrogenic pain syndrome, Lumbalgia
+∞
139.7
132
*
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
65.6
135.9
75
12
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
16.2
129.9
113
75
72510
ICD-8 Finland
Displacement of intervertebral disk, Lumbalis cum prolapsu disci
+∞
125.7
119
*
72880
ICD-8 Finland
Vertebrogenic pain syndrome, Radicula syndrome of lower limbs
+∞
115.0
109
*
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
26.8
114.1
79
31
M54.9
ICD-10 Finland
Dorsalgia, unspecified
7.1
98.8
158
245
71798
ICD-8 Finland
Other nonarticular rheumatism, Other muscular rheumatism, fibrositis and myalgia
22.2
94.1
70
33
N03AX16
ATC
[U] pregabalin
3.9
90.4
325
1003
N02AX02
ATC
tramadol; systemic, rectal
2.9
89.2
688
3353
M47.9
ICD-10 Finland
Spondylosis, unspecified
31.1
86.6
57
19
71319
ICD-8 Finland
Osteo-arthritis and allied conditions, Spondylarthritis NUD
+∞
85.2
81
*
M54.5
ICD-10 Finland
Low back pain
3.4
81.1
359
1263
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
6.3
79.8
142
245
N03AX12
ATC
[U] gabapentin; oral
4.5
78.8
216
544
72800
ICD-8 Finland
Vertebrogenic pain syndrome, Cervicalgia
40.3
76.9
47
12
M45
ICD-10 Finland
Ankylosing spondylitis
205.1
75.9
78
*
35399
ICD-8 Finland
Sciatica
11.3
74.2
79
73
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
21.0
67.2
51
25
M54.4
ICD-10 Finland
Lumbago with sciatica
5.0
65.5
151
329
A07EC01
ATC
sulfasalazine; oral, rectal
4.9
64.6
153
341
7227C
ICD-9 Finland
Intervertebral disk disorders, Intervertebral disk disorder with myelopathy[SYNDROMA ISCHIADICUM]
+∞
64.0
61
*
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
21.5
63.8
48
23
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
95.3
58.3
64
7
M47.82
ICD-10 Finland
Other spondylosis, cervical region
15.5
58.0
51
34
71311
ICD-8 Finland
Osteo-arthritis and allied conditions, Spondylarthritis thoracica
+∞
56.6
54
*
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
14.2
51.1
47
34
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
+∞
49.2
47
*
78050
ICD-8 Finland
Certain symptoms referable to nervous system and special senses, Vertigo
6.7
48.8
79
123
71300
ICD-8 Finland
Osteo-arthritis and allied conditions, Arthritis (arthrosis) coxae
10.1
48.2
55
56
72820
ICD-8 Finland
Vertebrogenic pain syndrome, Diffuse syndrome cerviocobrachial
+∞
48.1
46
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.6
46.6
319
1391
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
15.7
46.0
40
26
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.2
43.3
195
677
72898
ICD-8 Finland
Vertebrogenic pain syndrome, Alia definita
+∞
42.9
41
*
M43.1
ICD-10 Finland
Spondylolisthesis
17.9
42.9
35
20
N06AA09
ATC
amitriptyline; systemic
3.5
42.4
160
498
71301
ICD-8 Finland
Osteo-arthritis and allied conditions, Arthritis (arthrosis) genus
6.4
41.4
70
114
M54.3
ICD-10 Finland
Sciatica
7.6
41.2
59
80
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
92.6
41.0
45
5
7231A
ICD-9 Finland
Other disorders of cervical region, Cervicalgia
+∞
40.8
39
*
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
5.2
40.7
86
173
7213A
ICD-9 Finland
Spondylosis and allied disorders, Lumbosacral spondylosis without myelopathy
+∞
39.7
38
*
7240B
ICD-9 Finland
Other and unspecified disorders of back, Spinal stenosis, other than cervical[STENOSIS CANALIS SPINALIS LUMBOSACRALIS]
+∞
39.7
38
*
7210A
ICD-9 Finland
Spondylosis and allied disorders, Cervical spondylosis without myelopathy
+∞
39.7
38
*
27799
ICD-8 Finland
Obesity not specified as of endocrine origin
9.1
39.0
48
54
71710
ICD-8 Finland
Other nonarticular rheumatism, Scapulohumeral myofibrosis
9.2
36.9
45
50
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.1
36.7
446
2467
M03BX02
ATC
tizanidine; oral
2.0
35.7
541
3244
9212
FHL
Other posterior root decompression surgery (eg laminectomy, Gill)
354.6
35.1
35
*
N06AX21
ATC
duloxetine; oral
3.6
34.8
122
361
M54.2
ICD-10 Finland
Cervicalgia
4.8
34.1
79
172
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
8.5
33.0
43
52
N02AC04
ATC
dextropropoxyphene; oral
3.2
32.7
138
459
72899
ICD-8 Finland
Vertebrogenic pain syndrome, Other and unspecified
+∞
32.4
31
*
M54.1
ICD-10 Finland
Radiculopathy
9.9
32.1
37
38
40199
ICD-8 Finland
Essential benign hypertension
3.7
31.9
107
307
N05BA01
ATC
diazepam; systemic, rectal
2.4
29.7
233
1067
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.3
29.7
251
1188
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.0
29.6
463
2771
M03BC01
ATC
orphenadrine (citrate); systemic
2.7
29.5
173
689
M54.6
ICD-10 Finland
Pain in thoracic spine
4.9
29.3
66
140
72830
ICD-8 Finland
Vertebrogenic pain syndrome, Radicular syndrome of upper limbs
+∞
29.2
28
*
7245A
ICD-9 Finland
Other and unspecified disorders of back, Backache, unspecified
+∞
29.2
28
*
L04AX03
ATC
methotrexate; systemic
3.3
28.7
113
360
79199
ICD-8 Finland
Headache
6.3
28.4
48
78
M53.1
ICD-10 Finland
Cervicobrachial syndrome
3.7
26.8
87
244
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
28.3
26.7
36
13
H02AB06
ATC
prednisolone; systemic
1.8
26.4
644
4407
E9999
ICD-8 Finland
Late effect of injury due to war operations
10.5
26.2
29
28
30041
ICD-8 Finland
Neuroses, Depressiva
5.8
26.0
48
85
M25.5
ICD-10 Finland
Pain in joint
2.1
26.0
275
1421
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
264.5
25.8
26
*
9211
FHL
Exploration or removal of diskusprolapse
264.5
25.8
26
*
N02BF01
ATC
gabapentin; oral
3.6
25.6
87
252
A02BC05
ATC
esomeprazole; systemic
1.9
25.0
470
2960
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
132.0
24.6
26
*
M01AH01
ATC
celecoxib; oral
2.2
24.3
230
1136
R07.3
ICD-10 Finland
Other chest pain
2.7
24.2
143
571
R51.80
ICD-10 Finland
Headache
2.6
23.9
153
635
40299
ICD-8 Finland
Hypertensive heart disease
4.5
23.7
58
132
Y0599
ICD-8 Finland
Investigation of digestive system
4.3
23.1
60
143
ABC16
NOMESCO Finland
Microsurgical excision of lumbar intervertebral disc displacement
+∞
23.0
22
*
L86
ICPC
Back syndrome with radiating pain
4.3
21.9
57
136
71700, ,
ICD-8 Finland
+∞
21.9
21
*
A02BA02
ATC
ranitidine; systemic
1.9
21.8
365
2202
M79.0
ICD-10 Finland
Rheumatism, unspecified
6.6
21.7
35
54
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.6
21.6
135
553
L03
ICPC
Low back symptom/complaint
2.1
21.5
220
1116
71308
ICD-8 Finland
Osteo-arthritis and allied conditions, Arthritis (arthrosis) alia (spinali excepta)
8.8
21.5
27
31
41399
ICD-8 Finland
Angina pectoris, Without mention of hypertensive disease
3.6
21.3
71
203
A02BC01
ATC
omeprazole; systemic
1.8
21.3
430
2745
M54.8
ICD-10 Finland
Other dorsalgia
5.5
21.2
41
76
M01AC06
ATC
meloxicam; systemic, rectal
1.8
21.1
400
2503
G44.2
ICD-10 Finland
Tension-type headache
2.7
21.1
122
481
M79.6
ICD-10 Finland
Pain in limb
1.8
20.5
404
2555
M01AX17
ATC
nimesulide; oral
1.9
20.4
335
2002
J01DA01
ATC
[U] cefalexin
1.7
20.4
861
6684
A02BC03
ATC
lansoprazole; oral
1.8
20.3
408
2594
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.7
20.2
535
3674
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.7
20.0
606
4312
M47.1
ICD-10 Finland
Other spondylosis with myelopathy
+∞
19.8
19
*
M01AH02
ATC
rofecoxib; oral
2.1
19.5
202
1029
R07.4
ICD-10 Finland
Chest pain, unspecified
1.8
19.2
343
2101
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
6.6
19.2
31
48
L04AB01
ATC
etanercept; parenteral
20.3
19.1
28
14
M19.0
ICD-10 Finland
Primary arthrosis of other joints
2.8
18.8
99
372
71240
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Spondylitis ankylopoietica
+∞
18.8
18
*
L88
ICPC
Rheumatoid/seropositive arthritis
4.2
18.7
50
122
ABC56
NOMESCO Finland
Decompression of lumbar spinal canal and nerve roots
192.0
18.6
19
*
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
5.2
18.4
38
75
R03AC02
ATC
salbutamol; inhalant
1.6
18.3
597
4302
L04AB04
ATC
adalimumab; parenteral
17.8
18.2
28
16
M01AB55
ATC
diclofenac, combinations; oral
2.5
18.0
123
526
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.9
17.6
271
1581
M01AH05
ATC
etoricoxib; oral
1.7
17.6
494
3419
XA402
NOMESCO Finland
ENMG
6.4
17.5
29
46
M47.8
ICD-10 Finland
Other spondylosis
181.7
17.5
18
*
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.2
17.5
69
220
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
3.8
17.2
52
139
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.6
17.0
547
3908
J45.9
ICD-10 Finland
Asthma, unspecified
1.9
16.9
233
1310
UJF32
NOMESCO Finland
Coloscopy
1.8
16.8
320
1988
7200A
ICD-9 Finland
Ankylosing spondylitis and other inflammatory spondylopathies, Ankylosing spondylitis
+∞
16.7
16
*
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
2.6
16.6
102
414
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
4.7
16.6
38
82
75618
ICD-8 Finland
Other congenital anomalies of musculoskeletal system, Maleformationes columnae vertebralis aliae
23.3
16.4
23
10
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
2.6
16.4
94
369
M01AE03
ATC
ketoprofen; systemic, rectal
1.6
16.2
501
3539
M70.6
ICD-10 Finland
Trochanteric bursitis
2.3
16.1
127
579
M01AB05
ATC
diclofenac; systemic, rectal
1.6
16.0
667
5049
N05CF01
ATC
zopiclone; oral
1.6
15.9
542
3915
J01AA02
ATC
doxycycline; systemic
1.6
15.9
983
8139
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
2.7
15.8
84
317
C01DA14
ATC
isosorbide mononitrate; oral
1.6
15.8
462
3214
G55.1*M51.1
ICD-10 Finland
Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions
60.6
15.8
18
*
7151F
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, primary[OSTEOARTHROSIS PRIMARIA, POLVI]
2.9
15.7
75
267
73599
ICD-8 Finland
Other and unspecified curvature of spine
+∞
15.6
15
*
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
3.0
15.6
70
241
J46
ICD-10 Finland
Status asthmaticus
3.7
15.4
48
131
L01BA01
ATC
methotrexate; systemic
3.5
15.3
53
156
M13.9
ICD-10 Finland
Arthritis, unspecified
2.7
15.2
82
312
R06.0
ICD-10 Finland
Dyspnoea
1.7
15.1
371
2463
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
14.7
362
2403
I20.09
ICD-10 Finland
Unstable angina
2.2
14.6
129
615
72850
ICD-8 Finland
Vertebrogenic pain syndrome, Pain in thoracic spine
+∞
14.6
14
*
N02AJ06
ATC
codeine and paracetamol; systemic
1.7
14.6
316
2028
42700
ICD-8 Finland
Symptomatic heart disease, Congestive heart failure
4.1
14.5
40
100
M46.4
ICD-10 Finland
Discitis, unspecified
151.1
14.5
15
*
R42
ICD-10 Finland
Dizziness and giddiness
1.7
14.4
338
2215
N06AB04
ATC
citalopram; systemic
1.7
14.3
289
1819
M03BC51
ATC
orphenadrine, combinations; systemic
1.8
14.3
226
1324
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
4.5
14.2
34
76
J01FA06
ATC
roxithromycin; oral
1.6
14.1
493
3561
M09AA72
ATC
quinine, combinations with psycholeptics; systemic
2.2
13.6
113
525
R06AE07
ATC
cetirizine; oral
1.6
13.6
409
2848
ABC26
NOMESCO Finland
Open discectomy of lumbar spine
+∞
13.5
13
*
71303
ICD-8 Finland
Osteo-arthritis and allied conditions, Arthritis (arthrosis) multiplex
11.0
13.5
25
23
H04.10
ICD-10 Finland
Dry eye syndrome
2.2
13.4
110
509
M01AC01
ATC
piroxicam; systemic, rectal
1.9
13.3
171
936
41397
ICD-8 Finland
Angina pectoris, Suspecta, hypertonia non indicata
4.1
13.3
36
89
M02AA10
ATC
ketoprofen; topical
1.8
13.2
204
1186
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.9
12.9
165
901
41299
ICD-8 Finland
Chronic ischaemic heart disease, Without mention of hypertensive disease
4.0
12.9
36
91
78739
ICD-8 Finland
Symptoms referable to limbs and joints, Arthralgia alia sive NUD
14.2
12.7
21
15
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
12.7
197
1146
A02BA04
ATC
nizatidine; systemic
1.9
12.7
160
871
J02AC01
ATC
fluconazole; systemic
1.6
12.5
325
2176
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.7
12.5
69
266
72519
ICD-8 Finland
Displacement of intervertebral disk, Lumbalis et lumbosacralis NUD
+∞
12.5
12
*
72810
ICD-8 Finland
Vertebrogenic pain syndrome, Cervicocranial syndrome
+∞
12.5
12
*
M51.9
ICD-10 Finland
Intervertebral disc disorder, unspecified
+∞
12.5
12
*
M46.3
ICD-10 Finland
Infection of intervertebral disc (pyogenic)
+∞
12.5
12
*
NAG40
NOMESCO Finland
Anterior fusion of cervical spine without fixation
+∞
12.5
12
*
A06AD11
ATC
lactulose; oral
1.6
12.5
355
2432
A03CA02
ATC
clidinium and psycholeptics; oral
2.2
12.4
107
506
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
11.7
12.3
22
19
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
5.4
12.3
24
45
30040
ICD-8 Finland
Neuroses, Neurotico-depressiva
9.0
12.2
25
28
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
3.0
12.1
53
180
G55.2*M47.9
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
26.9
12.0
16
6
M01AE01
ATC
ibuprofen; systemic, rectal
1.5
11.9
922
7757
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
11.9
222
1362
L04AB06
ATC
golimumab; parenteral
47.0
11.9
14
*
M54
ICD-10 Finland
Dorsalgia
2.3
11.7
88
393
45599
ICD-8 Finland
Haemorrhoids
2.5
11.7
76
318
P01BA02
ATC
hydroxychloroquine; oral
2.4
11.7
81
349
A02BC02
ATC
pantoprazole; systemic
1.5
11.6
769
6265
4019X
ICD-9 Finland
Essential hypertension, Unspecified
2.1
11.6
109
533
R52.2
ICD-10 Finland
Other chronic pain
3.8
11.6
35
94
H02AB04
ATC
methylprednisolone; systemic
1.8
11.5
188
1109
NAG63
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, more than 3 vertebraea
+∞
11.5
11
*
7228C
ICD-9 Finland
Intervertebral disk disorders, Postlaminectomy syndrome[SYNDROMA LUMBOSACRALE POSTLAMINECTOMIAM]
+∞
11.5
11
*
N02BF02
ATC
pregabalin; oral
3.1
11.5
47
154
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.8
11.4
179
1043
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
11.4
500
3754
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.9
11.3
157
882
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
3.2
11.3
44
140
M02AA07
ATC
piroxicam; topical
1.5
11.2
481
3591
I20.99
ICD-10 Finland
Angina pectoris, unspecified
1.9
11.2
157
884
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
1.6
11.1
292
1956
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
2.8
11.1
55
201
M01AE51
ATC
ibuprofen, combinations; systemic
4.2
11.1
29
70
A07EC02
ATC
mesalazine; oral, rectal
2.8
11.0
56
207
41300
ICD-8 Finland
Angina pectoris, Cum hypertonia
3.8
11.0
33
88
M50.3
ICD-10 Finland
Other cervical disc degeneration
15.6
10.8
17
11
M16.1
ICD-10 Finland
Other primary coxarthrosis
1.8
10.8
162
932
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.1
10.8
100
487
NBL00
NOMESCO Finland
Suture or reinsertation of rotator cuff of shoulder
2.8
10.7
53
193
72410
ICD-8 Finland
Internal derangement of joint, Other shoulder derangement
2.6
10.7
61
239
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
10.6
158
906
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.5
10.6
359
2546
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.9
10.5
130
703
7233A
ICD-9 Finland
Other disorders of cervical region, Cervicobrachial syndrome (diffuse)
+∞
10.4
10
*
7214A
ICD-9 Finland
Spondylosis and allied disorders, Thoracic or lumbar spondylosis with myelopathy
+∞
10.4
10
*
7225A
ICD-9 Finland
Intervertebral disk disorders, Degeneration of thoracic or lumbar intervertebral disk[DEGENERATIO DISCI INTERVERTEBRALIS THORAC SEU LUMB]
+∞
10.4
10
*
72500
ICD-8 Finland
Displacement of intervertebral disk, Cervicalis cum prolapsu disci
+∞
10.4
10
*
7244A
ICD-9 Finland
Other and unspecified disorders of back, Thoracic or lumbosacral neuritis or radiculitis, unspecified
+∞
10.4
10
*
72509
ICD-8 Finland
Displacement of intervertebral disk, Cervicalis NUD
+∞
10.4
10
*
M01AE02
ATC
naproxen; oral, rectal
1.5
10.4
540
4173
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
5.2
10.3
21
41
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.7
10.2
55
210
A02BA03
ATC
famotidine; systemic
2.2
10.2
83
384
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
1.5
10.1
447
3346
49099
ICD-8 Finland
Bronchitis, unspecified
4.2
10.1
26
62
NFC20
NOMESCO Finland
Secondary implantation of hip prosthesis
3.6
10.1
32
89
M79.1
ICD-10 Finland
Myalgia
2.0
10.1
107
548
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
11.4
10.0
18
16
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.3
10.0
76
341
78719
ICD-8 Finland
Symptoms referable to limbs and joints, Dolor extremitatis aliud sive NUD
10.1
10.0
19
19
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
4.6
10.0
23
50
M48.9
ICD-10 Finland
Spondylopathy, unspecified
40.3
10.0
12
*
N02AA05
ATC
oxycodone; systemic
1.6
9.9
280
1904
M19.9
ICD-10 Finland
Arthrosis, unspecified
2.7
9.9
53
202
A03FA02
ATC
cisapride; oral, rectal
1.9
9.8
135
755
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.6
9.8
235
1536
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
9.8
217
1391
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.2
9.8
79
364
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.5
9.7
478
3646
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.6
9.7
258
1729
A03DA02
ATC
pitofenone and analgesics; systemic
2.8
9.7
49
181
A01
ICPC
Pain general/multiple sites
2.0
9.7
100
507
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.7
9.7
205
1299
M01AG02
ATC
tolfenamic acid; oral, rectal
2.0
9.7
113
599
N05BA04
ATC
oxazepam; oral
1.5
9.6
348
2496
L04AC10
ATC
secukinumab; parenteral
55.3
9.6
11
*
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
55.3
9.6
11
*
L17
ICPC
Foot/toe symptom/complaint
1.6
9.6
259
1741
N06AX11
ATC
mirtazapine; oral
1.5
9.6
363
2629
N06AX16
ATC
venlafaxine; oral
2.1
9.6
92
454
M01AX01
ATC
nabumetone; oral
2.6
9.6
55
217
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.9
9.6
119
644
X58
ICD-10 Finland
Exposure to other specified factors
1.9
9.6
121
659
L04AA13
ATC
[U] leflunomide
4.6
9.5
22
48
R03DC03
ATC
montelukast; oral
1.9
9.5
131
734
R05FB02
ATC
cough suppressants and expectorants; systemic
1.4
9.4
525
4093
NA6CG
NOMESCO Finland
Sacro-iliac joint extensive MRI examination with high intensity magnet
100.5
9.4
10
*
7249X
ICD-9 Finland
Other and unspecified disorders of back, Other unspecified back disorders
+∞
9.4
9
*
ABC30
NOMESCO Finland
Decompression of cervical nerve roots
+∞
9.4
9
*
N30.0
ICD-10 Finland
Acute cystitis
1.6
9.3
215
1392
M01AH03
ATC
valdecoxib; oral
2.5
9.2
57
233
E66.9
ICD-10 Finland
Obesity, unspecified
3.5
9.2
31
90
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.9
9.2
109
581
C07AA05
ATC
propranolol; systemic
1.7
9.1
171
1050
B01AB05
ATC
enoxaparin; parenteral
1.5
9.1
331
2377
J01DA08
ATC
[U] cefaclor
2.1
9.0
87
430
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.5
9.0
56
230
K59.0
ICD-10 Finland
Constipation
2.0
8.9
99
515
H57.1
ICD-10 Finland
Ocular pain
3.2
8.9
35
112
213
Kela drug reimbursment
Fat metabolism disorder associated with chronic coronary artery disease
1.7
8.9
176
1094
R01BA52
ATC
pseudoephedrine, combinations; oral
1.6
8.9
237
1589
M54.0
ICD-10 Finland
Panniculitis affecting regions of neck and back
12.6
8.9
15
12
A07AA02
ATC
nystatin; oral
2.1
8.9
84
413
R53
ICD-10 Finland
Malaise and fatigue
1.5
8.8
335
2422
M53.0
ICD-10 Finland
Cervicocranial syndrome
2.5
8.8
55
226
M79.7
ICD-10 Finland
Fibromyalgia
4.5
8.8
21
47
L02
ICPC
Back symptom/complaint
2.3
8.8
69
314
M03BB53
ATC
chlorzoxazone, combinations excl. psycholeptics; oral
4.0
8.8
24
60
R52.9
ICD-10 Finland
Pain, unspecified
2.1
8.8
87
435
C07AB02
ATC
metoprolol; systemic
1.4
8.7
414
3125
L84
ICPC
Back syndrome without radiat pain
2.9
8.7
39
135
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
2.9
8.7
41
146
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
2.0
8.7
92
471
M04AA01
ATC
allopurinol; systemic
1.6
8.7
247
1679
M01AB51
ATC
indometacin, combinations; oral, rectal
3.1
8.7
35
114
M15.0
ICD-10 Finland
Primary generalized (osteo)arthrosis
2.9
8.7
40
141
A02BX02
ATC
sucralfate; oral
2.0
8.6
88
445
J01DB01
ATC
cefalexin; oral
1.4
8.6
879
7561
73398
ICD-8 Finland
Other diseases of muscle, tendon and fascia, Alii definiti
4.8
8.6
19
40
53503
ICD-8 Finland
Gastritis and duodenitis, Gastritis chronica NUD
8.3
8.6
18
22
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
16.4
8.5
13
8
78551
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Symptomata abdominalis acuta NUD
3.0
8.5
37
126
2402
FHL
External neurolysis of the nerve and possible alteration of the pathway (nerve pressure)
3.3
8.5
31
95
201
Kela drug reimbursment
Chronic cardiac insufficiency
1.6
8.5
192
1237
S22.3
ICD-10 Finland
Fracture of rib
2.0
8.4
91
470
2780A
ICD-9 Finland
Obesity and other hyperalimentation, Obesity
4.9
8.3
18
37
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
2.5
8.3
52
214
72840
ICD-8 Finland
Vertebrogenic pain syndrome, Cervial myelopathy
+∞
8.3
8
*
WX308
NOMESCO Finland
Sacral anesthesy
+∞
8.3
8
*
7225B
ICD-9 Finland
Intervertebral disk disorders, Degeneration of thoracic or lumbar intervertebral disk[DEGEN DISCI INTERVERT THORAC SEU LUMBOSACR CUM INST]
+∞
8.3
8
*
J01FF01
ATC
clindamycin; systemic
1.5
8.3
275
1934
C03CA01
ATC
furosemide; systemic
1.4
8.2
715
5972
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.6
8.2
209
1384
56210
ICD-8 Finland
Diverticula of intestine, Diverticulum (diverticulosis) coli
6.5
8.2
20
31
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
2.4
8.1
54
229
55130
ICD-8 Finland
Other hernia of abdominal cavity without mention of obstruction, Diaphragmatic
4.6
8.1
19
42
L01
ICPC
Neck symptom/complaint
1.9
8.1
108
599
R35
ICD-10 Finland
Polyuria
2.1
8.0
78
387
N05CD07
ATC
temazepam; oral
1.5
8.0
276
1953
R51.81
ICD-10 Finland
Facial pain NOS
4.2
8.0
21
51
NBA30
NOMESCO Finland
Exploration of joint of shoulder or upper arm, arthroscopic
3.9
8.0
23
60
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.1
7.9
77
382
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
7.9
272
1924
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
7.9
312
2270
ZYC01
NOMESCO Finland
Remote contact by phone
2.5
7.8
48
196
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
2.7
7.8
42
161
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
1.9
7.8
97
526
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
1.7
7.8
132
787
G04CA02
ATC
tamsulosin; oral
1.4
7.8
404
3092
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
2.5
7.8
47
191
M51.8
ICD-10 Finland
Other specified intervertebral disc disorders
45.1
7.7
9
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.4
7.7
529
4243
NBG10
NOMESCO Finland
Acromioplastia
3.2
7.7
30
96
N06AB03
ATC
fluoxetine; oral
1.8
7.7
112
639
71239
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides NUD
4.0
7.6
21
53
35708
ICD-8 Finland
Other diseases of peripheral nerves except autonomic, Alterius nervi
8.1
7.6
16
20
79020
ICD-8 Finland
Nervousness and debility, Depression
11.9
7.6
13
11
J01FA09
ATC
clarithromycin; systemic
1.5
7.5
245
1712
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.7
7.5
154
966
1220
FHL
Arthroscopy
2.6
7.5
43
170
B01AC07
ATC
dipyridamole; systemic
1.6
7.5
174
1126
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.5
7.5
249
1748
SPAT1097
SPAT
Recording of ECG
1.6
7.5
163
1039
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.4
7.4
554
4494
E000001, ,
ATC
1.5
7.4
222
1523
M01AB01
ATC
indometacin; systemic, rectal
1.7
7.4
130
782
L04AB05
ATC
certolizumab pegol; parenteral
80.3
7.4
8
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
1.8
7.4
101
564
ZXA05
NOMESCO Finland
Left side
1.4
7.4
319
2358
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
7.4
326
2420
J01DA09
ATC
[U] cefadroxil
1.5
7.3
305
2239
N06AX03
ATC
mianserin; oral
2.2
7.3
63
299
AA1AD
NOMESCO Finland
CT of head and brain
1.4
7.3
373
2841
J01MA02
ATC
ciprofloxacin; systemic
1.4
7.3
503
4028
NF1AA
NOMESCO Finland
Hip X-ray examination
1.7
7.3
123
732
72599
ICD-8 Finland
Displacement of intervertebral disk, Unspecified site
+∞
7.3
7
*
M46.8
ICD-10 Finland
Other specified inflammatory spondylopathies
+∞
7.3
7
*
7242A
ICD-9 Finland
Other and unspecified disorders of back, Lumbago
+∞
7.3
7
*
7221A
ICD-9 Finland
Intervertebral disk disorders, Displacement of thoracic or lumbar intervertebral disk without myelopathy
+∞
7.3
7
*
G99.2*M47.1
ICD-10 Finland
Spondylogenic compression of spinal cord
+∞
7.3
7
*
7373A
ICD-9 Finland
Curvature of spine, Kyphoscoliosis and scoliosis
+∞
7.3
7
*
M01AX05
ATC
glucosamine; oral
1.5
7.3
243
1708
42798
ICD-8 Finland
Symptomatic heart disease, Alia arrhytmia definita
3.2
7.2
27
84
L04AX01
ATC
azathioprine; systemic
2.7
7.2
38
144
L03.0
ICD-10 Finland
Cellulitis of finger and toe
2.1
7.2
70
348
D12
ICPC
Constipation
2.3
7.2
51
223
N05CD05
ATC
triazolam; oral, sublingual
2.6
7.2
40
156
4111X
ICD-9 Finland
Other acute and subacute forms of ischaemic heart disease, Intermediate coronary syndrome[PITKITTYNYT ANGINA PECTORIS -KOHTAUS,MÄÄRITTELEMÄT]
2.5
7.2
42
168
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
2.5
7.2
43
174
SPAT1229
SPAT
Assessment of need for aid
1.8
7.2
109
630
SPAT1301
SPAT
No procedures
1.4
7.1
344
2593
I82.9
ICD-10 Finland
Embolism and thrombosis of unspecified vein
3.1
7.1
28
90
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.5
7.1
294
2154
K30
ICD-10 Finland
Functional dyspepsia
1.9
7.1
85
455
R03BA02
ATC
budesonide; inhalant
1.6
7.1
187
1247
34609
ICD-8 Finland
Migraine, Unspecified
6.0
7.1
18
30
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
2.8
7.1
34
123
C02DE04, ,
ATC
1.8
7.1
96
536
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.6
7.0
172
1127
M75.9
ICD-10 Finland
Shoulder lesion, unspecified
2.6
7.0
38
146
7865A
ICD-9 Finland
Symptoms involving respiratory system and other chest symptoms, Chest pain
2.6
7.0
39
152
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.5
7.0
224
1558
A46
ICD-10 Finland
Erysipelas
1.5
7.0
198
1343
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
3.3
7.0
25
76
A03FA01
ATC
metoclopramide; systemic, rectal
1.5
7.0
250
1782
I50.9
ICD-10 Finland
Heart failure, unspecified
1.4
6.9
389
3007
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
2.1
6.9
66
326
N02BE01
ATC
paracetamol; systemic, rectal
1.4
6.9
1001
8935
E990A
ICD-9 Finland
Injury due to war operations by fires and conflagrations
5.9
6.9
18
31
7151E
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, primary[OSTEOARTHROSIS PRIMARIA, LONKKANIVEL]
2.6
6.9
39
154
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
2.2
6.8
56
261
M76.9
ICD-10 Finland
Enthesopathy of lower limb, unspecified
9.3
6.8
13
14
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.6
6.8
148
944
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.5
6.7
269
1958
N06AA12
ATC
doxepin; systemic
1.9
6.7
76
400
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.8
6.7
98
560
4130X
ICD-9 Finland
Angina pectoris, Angina decubitus[ANGINA PECTORIS (""""EFFORT ANGINA""""),MÄÄRITTELEMÄT]
1.9
6.7
81
436
62700
ICD-8 Finland
Menopausal symptoms
22.6
6.7
9
*
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
3.0
6.6
28
94
N02BA71
ATC
acetylsalicylic acid, combinations with psycholeptics; systemic
2.7
6.6
35
133
NA3BG, ,
SPAT
3.7
6.6
20
54
SAA04
NOMESCO Finland
Special examination of mouth
2.5
6.6
40
163
H26.4
ICD-10 Finland
After-cataract
1.6
6.6
180
1210
M75.2
ICD-10 Finland
Bicipital tendinitis
3.6
6.6
21
59
71599
ICD-8 Finland
Arthritis, unspecified
12.3
6.6
11
9
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
1.9
6.5
74
390
D07AC01
ATC
betamethasone; topical
1.4
6.5
365
2820
M16.9
ICD-10 Finland
Coxarthrosis, unspecified
2.0
6.4
68
349
M48.1
ICD-10 Finland
Ankylosing hyperostosis [Forestier]
70.0
6.4
7
*
30320
ICD-8 Finland
Alcoholism, Alcoholic addiction
3.2
6.4
24
75
R03AC03
ATC
terbutaline; inhalant
1.6
6.4
147
949
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
1.9
6.4
84
464
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
3.3
6.4
23
70
62699
ICD-8 Finland
Disorders of menstruation, Other
2.4
6.4
43
184
L08
ICPC
Shoulder symptom/complaint
1.6
6.4
168
1120
S99.9
ICD-10 Finland
Unspecified injury of ankle and foot
3.8
6.4
19
51
G04BD01
ATC
emepronium; systemic
3.1
6.3
26
86
7261X
ICD-9 Finland
Peripheral enthesopathies and allied syndromes, Rotator cuff syndrome of shoulder and allied disorders[MUU TAI TARKEMMIN MÄÄRITTELEM KIERTÄJÄKALVOSINSDR]
5.2
6.3
18
35
M19.2
ICD-10 Finland
Other secondary arthrosis
5.5
6.3
17
31
C01CA24
ATC
epinephrine; parenteral
2.6
6.3
36
143
M03BB52
ATC
chlormezanone, combinations excl. psycholeptics; oral, rectal
2.8
6.3
31
114
30680
ICD-8 Finland
Special symptoms not elsewhere classified, Cephalalgia
18.1
6.3
9
5
H22.1*M45
ICD-10 Finland
Iridocyclitis in ankylosing spondylitis
+∞
6.2
6
*
9201
FHL
Anterior decompression surgery (also includes dees)
+∞
6.2
6
*
M42.0
ICD-10 Finland
Juvenile osteochondrosis of spine
+∞
6.2
6
*
G99.2
ICD-10 Finland
Myelopathy in diseases classified elsewhere
+∞
6.2
6
*
M53.2
ICD-10 Finland
Spinal instabilities
+∞
6.2
6
*
71313, ,
ICD-8 Finland
+∞
6.2
6
*
7232A
ICD-9 Finland
Other disorders of cervical region, Cervicocranial syndrome
+∞
6.2
6
*
7227A
ICD-9 Finland
Intervertebral disk disorders, Intervertebral disk disorder with myelopathy[KAULANIKAMAN VÄLILEVYTYRÄ JUURIOIREINEEN]
+∞
6.2
6
*
M50.8
ICD-10 Finland
Other cervical disc disorders
+∞
6.2
6
*
ABC99
NOMESCO Finland
Other decompressive operation on spinal cord or nerve root
+∞
6.2
6
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
6.2
432
3446
A12BA01
ATC
potassium chloride; oral
1.6
6.2
140
899
79019
ICD-8 Finland
Nervousness and debility, Debilitas et fatigatio abnormis alia sive NUD
26.7
6.2
8
*
SPAT1255
SPAT
Intravenous administration of medicine
1.9
6.2
78
425
M09AX01
ATC
hyaluronic acid; parenteral
1.9
6.2
81
447
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.0
6.2
62
313
I84.9
ICD-10 Finland
Unspecified hemorrhoids without complication
2.2
6.1
49
226
N06AA10
ATC
nortriptyline; systemic
5.4
6.1
17
32
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.5
6.1
191
1321
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.4
6.1
283
2112
72398
ICD-8 Finland
Other diseases of bone, Alii definiti
12.6
6.1
10
8
9061A
ICD-9 Finland
Late effects of injuries to skin and subcutaneous tissues, Late effect of open wound of extremities without mention of tendon injury
12.6
6.1
10
8
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.0
6.1
61
308
R03BA01
ATC
beclometasone; inhalant
1.5
6.1
163
1092
L28
ICPC
Limited function/disability (L)
1.4
6.1
256
1880
R06AE53
ATC
cyclizine, combinations; systemic
2.6
6.0
33
128

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
296
1936
1.66
12.54
5.6
4.5
1.02
1.02
kg/l
0.80
194
1301
149
820
1.90
11.39
1.3
1.2
13.33
18.01
u/ml
0.25
71
274
134
724
1.93
10.83
1.5
1.3
606.45
449.27
titre
0.39
31
164
156
897
1.82
10.39
1.3
1.2
15.93
41.62
iu/ml
6.51
54
302
36
107
3.42
10.28
1.0
1.1
—
—
—
0
0
354
2525
1.52
10.13
2.4
2.3
48.94
63.48
u/l
4.84
333
2291
118
642
1.91
9.34
2.7
2.0
198.67
159.61
ug/g
0.42
108
491
51
203
2.56
8.75
1.8
1.9
3.09
7.43
iu/ml
0.92
12
45
446
3426
1.43
8.53
4.5
3.7
6.41
6.30
ph
1.20
251
1900
284
2011
1.51
8.25
2.8
2.6
358.13
373.82
umol/l
1.43
246
1680
24
64
3.79
8.06
1.5
1.2
69121.89
256471.10
e6/l
0.70
18
41
533
4277
1.38
7.74
5.3
4.3
12.98
2.28
estimate
0.38
99
1010
482
3818
1.38
7.53
8.4
4.9
0.07
0.04
e9/l
0.46
438
3195
492
3931
1.37
7.23
8.8
5.0
0.19
0.20
e9/l
0.70
452
3312
533
4313
1.36
7.23
5.4
4.3
0.03
0.33
estimate
0.47
91
965
478
3802
1.37
7.22
8.4
4.9
0.62
0.63
e9/l
0.14
433
3171
524
4241
1.36
7.06
5.4
4.2
0.00
0.00
estimate
0.80
95
963
487
3908
1.36
6.90
8.5
5.0
2.23
1.77
e9/l
0.52
449
3357
535
4368
1.35
6.73
11.0
7.7
4.29
4.51
e9/l
1.18
484
3698
325
2450
1.41
6.69
5.7
4.2
0.00
0.01
estimate
1.15
84
778
152
980
1.61
6.66
1.9
1.7
—
—
—
0
0
94
542
1.78
6.25
1.6
1.5
—
—
—
0
0
84
471
1.83
6.12
3.3
2.5
11.26
11.04
g/l
0.15
74
422
410
3263
1.35
5.98
5.4
4.4
0.05
0.12
estimate
0.60
74
789
281
2114
1.40
5.79
2.9
2.8
5.05
5.57
e6/l
0.33
255
1925
443
3588
1.33
5.70
3.1
2.9
151.01
145.02
ug/l
0.16
406
3192
350
2737
1.36
5.68
2.4
2.3
3.19
3.16
mg/l
0.06
307
2279
42
188
2.27
5.68
1.7
1.4
22739.22
18784.25
e6/l
0.17
37
127
69
373
1.89
5.66
1.8
1.8
1.39
1.69
g/l
0.50
61
329
205
1465
1.46
5.59
6.2
4.3
—
—
—
0
0
529
4405
1.31
5.55
5.7
5.5
11.52
13.61
umol/l
2.95
509
4129
462
3784
1.32
5.45
5.4
4.4
168.77
96.03
ng/l
0.25
376
3010
50
249
2.04
5.21
10.9
12.0
—
—
—
0
0
345
2725
1.34
5.20
4.3
3.7
7.40
7.40
ph
0.37
251
1939
21
70
3.02
5.09
1.6
1.4
61.50
71.11
%
0.49
16
46
180
1283
1.45
4.98
1.2
1.2
0.79
1.82
u/ml
1.37
48
315
346
2752
1.33
4.95
2.8
2.4
—
—
—
0
0
295
2299
1.35
4.83
3.4
2.8
30.45
37.02
u/l
2.78
273
2144
494
4142
1.28
4.76
6.1
5.5
1.20
1.21
mmol/l
1.11
469
3728
425
3503
1.29
4.66
2.7
2.2
79.91
78.51
nmol/l
0.43
380
2985
19
63
3.04
4.66
1.5
1.3
40.83
22.08
%
1.07
13
40
108
701
1.58
4.65
2.1
2.2
0.00
0.03
estimate
0.50
18
109
39
186
2.12
4.58
1.6
1.4
230.53
254.30
ug/g
0.31
23
111
63
356
1.80
4.55
1.2
1.4
—
—
—
0
0
108
705
1.57
4.54
1.3
1.3
—
—
—
0
0
102
657
1.59
4.54
1.6
1.5
—
—
—
0
0
484
4071
1.28
4.50
5.2
4.4
34.26
33.91
g/l
0.65
446
3679
220
1660
1.38
4.41
2.5
2.4
11.10
11.11
umol/l
0.01
202
1500
20
71
2.84
4.38
1.3
1.7
0.49
0.98
g/l
1.41
14
58
118
793
1.53
4.37
2.9
3.1
5.65
4.54
e9/l
0.29
108
644
336
2705
1.31
4.36
2.3
2.0
203.40
268.01
u/l
0.81
315
2528
108
713
1.55
4.34
3.9
3.4
—
—
—
0
0
206
1543
1.39
4.32
1.5
1.5
1.66
1.68
mg/l
0.04
165
1230
548
4701
1.26
4.27
23.4
21.4
1.46
1.46
inr
0.02
481
3998
404
3350
1.28
4.16
4.5
3.6
—
—
—
0
0
371
3057
1.28
4.00
4.5
4.1
—
—
—
0
0
367
3020
1.28
4.00
4.0
3.5
52.82
126.13
e6/l
1.78
311
2342
432
3629
1.26
3.98
3.7
2.7
—
—
estimate
—
0
0
113
771
1.50
3.92
1.4
1.4
—
—
—
0
0
398
3320
1.27
3.87
4.8
4.0
118.11
171.91
e6/l
0.75
311
2421
201
1530
1.36
3.82
3.4
3.0
1.06
1.52
e6/l
1.38
124
836
279
2233
1.30
3.75
7.9
5.8
—
—
—
0
0
27
121
2.25
3.73
3.1
5.9
7.36
7.69
mmol/l
0.17
19
107
158
1161
1.40
3.72
4.2
5.2
7.42
7.42
ph
0.11
96
684
201
1538
1.35
3.69
2.5
2.4
2.22
2.22
g/l
0.01
188
1377
97
651
1.52
3.65
4.7
5.1
24.76
24.25
mmol/l
0.66
97
627
11
25
4.42
3.62
3.1
2.6
772.45
1616.92
u/ml
0.92
11
25
123
871
1.45
3.56
1.2
1.2
—
—
—
0
0
428
3633
1.25
3.54
8.5
5.1
9.14
9.22
%
0.20
407
3329
318
2610
1.27
3.50
7.6
4.7
—
—
—
0
0
100
683
1.49
3.48
5.2
3.9
1.55
0.93
%
0.76
44
232
426
3621
1.24
3.47
8.6
5.1
0.62
0.62
%
0.01
406
3314
426
3623
1.24
3.45
8.5
5.0
2.84
2.78
%
0.27
406
3325
154
1144
1.38
3.41
1.6
1.5
2.52
2.67
g/l
0.28
99
639
56
336
1.69
3.36
1.3
1.3
—
—
—
0
0
159
1192
1.37
3.34
2.1
1.8
—
—
—
0
0
128
926
1.42
3.31
4.5
5.8
118.67
118.58
g/l
0.02
128
906
30
150
2.02
3.20
1.5
1.4
—
—
—
0
0
429
3682
1.23
3.15
8.5
5.2
26.19
24.19
%
2.76
410
3442
403
3439
1.23
3.13
3.9
3.3
1824.39
2657.91
ng/l
3.74
369
2975
421
3610
1.23
3.12
8.3
5.1
57.87
60.37
%
3.68
405
3387
124
903
1.40
3.11
3.4
2.2
8.14
11.37
umol/l
1.13
111
771
154
1165
1.36
3.06
4.3
5.2
1.30
1.20
mmol/l
0.10
125
929
13
41
3.18
3.05
1.2
1.2
—
—
—
0
0
110
787
1.43
3.05
2.3
2.5
0.59
0.61
e6/l
0.04
105
756
102
723
1.44
2.98
1.7
1.6
—
—
—
0
0
231
1860
1.28
2.96
5.1
4.1
390.99
271.91
ng/l
0.27
200
1655
184
1438
1.32
2.94
2.4
2.4
19.90
20.35
%
0.21
172
1293
37
206
1.81
2.91
1.3
1.2
—
—
—
0
0
255
2087
1.26
2.86
3.5
3.6
0.00
0.09
—
5
154
574
5119
1.19
2.77
5.2
4.4
6.95
6.97
mmol/l
0.06
556
4847
684
6198
1.19
2.74
9.6
6.9
84.77
84.79
u/l
0.00
659
5710
246
2018
1.26
2.71
2.8
2.4
—
—
—
0
0
90
636
1.44
2.69
2.1
1.8
384.87
415.23
nmol/l
0.60
79
568
6
10
6.01
2.69
1.0
1.1
—
—
—
0
0
110
808
1.39
2.65
2.3
1.8
0.18
0.19
g/l
0.30
102
725
645
5830
1.18
2.63
7.1
5.3
2510.33
3532.44
e6/l
0.16
15
124
304
2563
1.23
2.61
3.9
3.4
0.36
0.58
e6/l
1.28
255
1948
22
107
2.07
2.56
1.2
1.2
6.88
42.95
e6/l
0.64
17
84
72
493
1.48
2.55
5.8
6.6
15.83
15.44
%
0.65
72
477
266
2220
1.24
2.51
1.9
1.9
1234.69
1127.91
nmol/l
1.03
219
1624
96
700
1.39
2.44
3.6
3.7
6.18
6.10
ph
0.43
67
543
86
618
1.41
2.38
2.9
3.5
—
—
—
0
0
524
4685
1.18
2.38
6.7
6.3
1.21
1.21
mmol/l
0.40
465
3904
32
188
1.71
2.17
1.2
1.2
—
—
—
0
0
24
129
1.87
2.16
1.5
1.4
—
—
—
0
0
41
259
1.60
2.12
1.2
1.1
—
192.67
—
0
6
87
642
1.37
2.09
2.9
3.6
7.41
7.41
ph
0.01
75
536
119
923
1.31
2.07
3.0
2.3
5.09
6.41
ug/l
0.93
97
745
179
1466
1.25
2.02
3.7
3.1
2.57
2.49
e6/l
0.04
101
768
76
552
1.39
2.02
3.3
3.0
23.94
24.00
mmol/l
0.05
76
536
171
2072
0.80
2.01
3.2
3.5
—
—
—
0
0
8
26
3.08
2.01
2.0
2.3
1.07
1.78
ug/l
—
8
18
8
26
3.08
2.01
1.7
1.1
21.66
21.23
umol/l
—
8
20
87
648
1.36
1.99
5.6
3.9
0.29
0.13
%
0.68
31
198
17
84
2.03
1.95
1.1
1.1
—
—
—
0
0
5
11
4.55
1.94
1.0
2.5
68.92
136.09
nmol/24h
—
5
11
54
372
1.47
1.92
2.2
2.0
0.00
0.01
estimate
0.49
16
85
279
2411
1.19
1.85
4.0
3.4
—
0.00
estimate
—
0
31
231
1965
1.20
1.82
3.1
3.0
2.47
2.47
mmol/l
0.21
194
1718
11
47
2.35
1.77
1.3
1.2
—
—
—
0
0
63
456
1.40
1.74
1.7
1.7
7.69
2.48
ug/l
0.32
54
379
49
339
1.46
1.73
2.9
3.9
24.51
25.08
mmol/l
0.52
43
292
8
30
2.67
1.72
1.0
1.3
121.13
129.43
nmol/l
—
8
30
18
96
1.88
1.70
1.3
1.2
—
—
—
0
0
93
720
1.31
1.68
3.2
2.1
31.75
33.86
u/l
0.28
73
594
314
2767
1.17
1.66
2.0
1.8
17.07
19.72
nmol/l
3.07
283
2303
16
83
1.93
1.64
1.2
1.2
—
—
—
0
0
104
823
1.28
1.60
2.9
2.3
66.89
65.31
g/l
1.32
94
723
261
2272
1.18
1.60
4.3
3.9
0.00
0.11
estimate
2.03
75
704
62
456
1.37
1.58
2.7
3.7
—
—
—
0
0
12
57
2.11
1.54
1.8
1.7
19.47
46.09
ng/l
0.72
12
57
82
635
1.31
1.50
5.9
4.3
1.50
0.25
%
0.56
28
177
484
4428
1.13
1.49
3.5
2.9
58.30
53.58
u/l
0.38
456
3998
82
636
1.30
1.49
5.1
3.9
1.02
0.88
%
0.23
33
209
49
351
1.41
1.47
2.6
3.0
8357.65
1651.73
u/ml
0.37
43
296
23
365
0.62
1.46
4.5
4.3
—
—
—
0
0
7
29
2.42
1.39
1.1
1.0
—
—
—
0
0
102
825
1.25
1.35
5.1
5.8
—
—
—
0
0
51
375
1.37
1.34
1.2
1.3
—
—
—
0
0
27
176
1.54
1.31
1.2
1.4
0.29
0.33
mg/l
0.14
13
72
344
3107
1.14
1.29
3.1
3.3
2.35
2.35
mmol/l
0.29
310
2727
13
69
1.89
1.28
2.2
1.6
7.32
8.31
mmol/l
0.60
13
69
10
48
2.09
1.27
2.4
2.0
—
—
—
0
0
6
25
2.40
1.24
1.0
1.0
1814.50
1515.68
miu/ml
—
6
25
11
201
0.54
1.22
2.8
2.2
4.35
4.13
mmol/l
0.56
11
196
17
101
1.69
1.19
1.1
1.2
—
—
—
0
0
11
199
0.55
1.18
2.8
2.3
1.20
1.19
mmol/l
0.11
11
194
241
2138
1.15
1.18
1.9
1.8
435.30
16309953.59
pmol/l
1.18
216
1680
8
38
2.11
1.18
1.3
1.5
12.06
13.92
umol/l
—
8
31
14
79
1.78
1.16
1.1
1.0
—
—
—
0
0
27
182
1.49
1.15
1.4
1.4
66.00
54.22
mmol/l
0.88
21
136
22
143
1.54
1.11
4.3
2.7
59.73
60.90
%
0.13
22
143
127
1077
1.19
1.10
3.3
3.1
2.11
1.91
mmol/l
0.19
108
870
13
73
1.78
1.10
1.2
1.2
—
—
—
0
0
593
5571
1.10
1.09
4.6
3.9
15.10
15.20
pmol/l
0.43
541
4869
228
2027
1.14
1.09
4.9
3.7
82.13
81.16
%
0.21
216
1978
7
32
2.19
1.08
1.4
1.3
28.21
10.66
%
—
7
26
15
89
1.69
1.07
1.2
1.2
372.10
331.89
u/ml
—
10
45
7
33
2.12
1.05
1.1
1.1
—
—
—
0
0
5
22
2.27
1.03
1.2
1.3
11.60
13.41
mm/h
—
5
22
7
35
2.00
1.00
1.1
1.1
—
—
—
0
0
11
61
1.81
0.98
2.5
1.8
14.37
15.59
%
0.59
11
61
0
31
0.00
0.96
0.0
6.9
—
9.32
—
0
31
143
1246
1.16
0.93
5.0
4.7
1.04
1.05
mmol/l
0.14
133
1111
6
28
2.14
0.91
3.0
1.8
—
—
—
0
0
20
135
1.49
0.88
1.2
1.2
—
—
—
0
0
629
5978
1.09
0.86
34.9
24.4
329.85
329.82
g/l
0.03
623
5881
442
4139
1.09
0.85
2.5
2.2
95.87
92.88
pmol/l
0.63
252
2183
146
1648
0.87
0.85
3.2
3.3
1.02
0.96
ug/l
0.11
97
1160
352
3265
1.10
0.83
15.0
11.3
0.00
0.00
e9/l
0.81
300
2615
16
105
1.53
0.81
2.1
1.6
247.63
292.37
mu/l
0.43
16
100
128
1122
1.15
0.79
3.4
3.1
7.37
7.37
ph
0.00
73
711
8
48
1.67
0.78
1.1
1.1
—
—
—
0
0
9
55
1.64
0.73
1.9
1.5
129.44
97.17
ng/l
—
9
55
169
1869
0.89
0.73
1.5
1.3
—
—
—
0
0
34
263
1.30
0.72
3.7
3.6
0.50
1.48
index
1.14
15
153
32
246
1.30
0.71
1.1
1.4
—
—
—
0
0
20
275
0.72
0.71
1.3
1.4
—
—
—
0
0
11
68
1.62
0.71
1.9
3.3
52.97
21.64
mg/l
—
6
53
17
117
1.46
0.71
3.5
2.7
4.84
4.84
e9/l
0.00
17
117
63
527
1.20
0.70
4.9
6.2
24.72
24.62
mmol/l
0.07
63
521
7
41
1.71
0.69
1.3
1.1
—
—
—
0
0
57
473
1.21
0.69
2.3
2.5
—
—
—
0
0
20
144
1.39
0.67
1.1
1.1
—
—
—
0
0
55
457
1.21
0.66
1.6
2.3
11.93
11.26
nmol/l
0.24
48
404
25
188
1.33
0.66
1.9
2.2
151.19
84.13
ug/min
0.42
15
106
88
765
1.16
0.64
3.9
3.3
116.01
101.33
ng/l
0.33
75
602
216
1985
1.10
0.64
3.2
3.1
526.33
536.95
mosm/kgh2o
0.36
189
1737
14
95
1.48
0.63
1.9
1.3
—
—
—
0
0
20
146
1.37
0.63
3.9
2.4
32.29
35.80
umol/l
0.35
14
130
10
63
1.59
0.61
1.1
1.1
—
—
—
0
0
45
371
1.22
0.60
2.8
3.2
4.41
4.33
pmol/l
0.23
40
316
8
52
1.54
0.59
1.0
1.1
—
—
—
0
0
11
72
1.53
0.58
1.2
1.1
6.80
5.06
u/ml
—
5
36
149
1351
1.11
0.58
2.0
2.1
1.87
1.76
%
0.60
129
1145
56
475
1.18
0.56
3.1
3.6
2.12
1.57
%
0.83
56
450
12
81
1.48
0.56
1.3
1.0
—
—
—
0
0
8
55
1.45
0.56
1.6
1.1
—
—
—
0
0
6
37
1.62
0.55
1.7
1.5
0.99
0.95
nmol/l
—
6
19
6
37
1.62
0.55
1.8
1.9
50.20
36.75
%
—
6
37
38
311
1.23
0.55
2.9
2.6
39.11
7.74
ratio
0.38
21
192
105
937
1.13
0.55
3.6
3.2
213.87
342.97
ng/l
2.78
100
852
20
261
0.76
0.54
1.5
1.7
3.48
3.44
mmol/l
0.05
12
187
14
99
1.42
0.53
1.6
2.5
—
—
—
0
0
11
74
1.49
0.53
1.3
1.1
—
—
—
0
0
11
74
1.49
0.53
1.3
1.1
—
—
—
0
0
13
91
1.43
0.52
1.5
1.4
—
—
—
0
0
13
91
1.43
0.52
1.5
1.4
—
—
—
0
0
13
91
1.43
0.52
1.5
1.4
—
—
—
0
0
13
91
1.43
0.52
1.5
1.4
—
—
—
0
0
284
3008
0.93
0.52
4.5
4.1
—
0.78
—
0
9
791
7681
1.06
0.52
28.1
18.4
28.71
30.74
mg/l
0.89
722
6567
689
7092
0.94
0.52
5.3
5.1
6.14
6.12
mmol/l
0.16
628
6166
9
63
1.43
0.52
1.7
3.2
—
—
—
0
0
6
40
1.50
0.51
1.8
1.4
—
—
—
0
0
52
444
1.18
0.50
1.3
1.2
—
—
—
0
0
111
1002
1.11
0.49
1.9
2.3
71.09
66.58
e9/l
0.55
84
744
39
325
1.20
0.49
1.2
1.2
98.52
151.35
u/ml
0.62
16
119
15
111
1.35
0.46
3.7
2.2
—
—
—
0
0
36
302
1.19
0.44
1.4
1.4
—
—
—
0
0
16
121
1.32
0.44
1.9
2.8
—
—
—
0
0
686
7035
0.95
0.43
5.7
5.4
2.46
2.49
mmol/l
0.27
629
6219
5
32
1.56
0.42
2.0
1.6
—
—
—
0
0
37
313
1.18
0.41
1.9
2.5
328.49
148.91
u/ml
0.53
37
303
8
58
1.38
0.41
1.1
1.2
—
—
—
0
0
10
70
1.43
0.41
1.0
1.1
—
—
—
0
0
5
33
1.51
0.41
3.0
3.1
85.40
134.33
nmol/l
—
5
33
0
15
0.00
0.41
0.0
2.3
—
0.80
—
0
15
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
5
34
1.47
0.40
3.4
3.6
—
—
—
0
0
13
171
0.76
0.40
2.7
1.8
55.15
60.24
%
0.40
13
171
6
41
1.46
0.36
1.7
1.3
—
—
—
0
0
656
6707
0.96
0.35
4.8
4.7
1.39
1.43
mmol/l
1.69
600
5892
14
108
1.30
0.35
1.9
2.0
1.14
1.21
g/24h
—
7
63
57
508
1.12
0.34
1.5
1.6
1.48
1.56
g/l
0.26
47
435
6
45
1.33
0.33
1.5
1.7
—
—
—
0
0
18
145
1.24
0.33
1.6
1.3
52646.15
19467.52
e6/l
0.48
13
85
630
6440
0.96
0.33
4.2
4.0
1.31
1.24
mmol/l
1.76
573
5598
6
46
1.30
0.33
1.0
1.9
4.97
11.91
umol/l
—
6
34
14
176
0.79
0.32
1.2
1.2
—
—
—
0
0
42
369
1.14
0.32
3.5
3.4
0.75
0.85
nmol/l
0.97
34
299
11
83
1.33
0.31
2.2
2.7
—
—
—
0
0
44
390
1.13
0.30
2.0
2.0
—
—
—
0
0
667
6798
0.96
0.30
4.9
4.7
4.31
4.36
mmol/l
0.60
625
6028
273
2617
1.05
0.30
3.0
3.3
6.75
6.87
mmol/l
0.20
232
2150
11
84
1.31
0.29
2.0
1.8
—
—
—
0
0
8
107
0.75
0.29
1.4
1.2
1.49
1.57
g/l
—
8
107
805
8170
0.96
0.28
39.5
27.6
127.72
129.10
g/l
1.63
796
7945
15
121
1.24
0.28
1.2
1.8
43.93
42.11
nmol/l
0.13
15
114
805
8169
0.96
0.28
39.5
27.7
38.42
38.34
%
0.13
796
7928
805
8169
0.96
0.28
39.0
27.3
4.24
4.30
e12/l
2.11
781
7817
805
8169
0.96
0.28
38.9
27.3
30.37
30.32
pg
0.29
797
7940
805
8168
0.97
0.28
39.2
27.3
239.42
238.53
e9/l
0.13
788
7856
10
76
1.32
0.28
1.0
1.1
—
—
—
0
0
805
8167
0.97
0.27
39.0
27.3
92.03
91.75
fl
0.83
797
7937
806
8172
0.97
0.26
39.1
27.4
7.90
7.11
e9/l
0.94
781
7818
8
67
1.19
0.26
1.4
1.2
—
—
—
0
0
63
684
0.92
0.25
1.5
1.4
—
—
—
0
0
9
74
1.22
0.25
1.4
1.3
264.67
277.96
mosm/kgh2o
—
9
52
9
74
1.22
0.25
1.3
1.2
0.73
25.26
nmol/l
—
9
69
14
114
1.23
0.24
2.5
1.7
85.41
88.49
%
0.54
14
114
680
6908
0.97
0.24
7.3
6.8
41.45
40.83
mmol/mol
0.91
634
6205
97
1030
0.94
0.23
1.4
1.4
—
—
—
0
0
50
546
0.91
0.23
1.6
1.5
—
—
—
0
0
769
7792
0.97
0.23
15.6
10.8
24.32
23.85
u/l
0.17
747
7396
5
38
1.31
0.23
4.0
1.8
91.60
95.89
umol/l
—
5
38
62
669
0.92
0.23
6.0
4.2
—
—
—
0
0
12
146
0.82
0.22
1.3
1.7
—
—
—
0
0
21
241
0.87
0.21
3.6
2.1
57.38
59.37
%
0.17
21
228
0
10
0.00
0.21
0.0
1.5
—
230.80
—
0
5
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
14
166
0.84
0.21
1.4
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
3.1
—
14.06
—
0
14
10
80
1.25
0.20
1.0
1.1
—
—
—
0
0
13
108
1.20
0.19
7.2
5.3
11.35
12.39
mg/l
0.48
13
95
6
51
1.18
0.19
1.3
1.7
—
—
—
0
0
107
1016
1.06
0.19
3.4
3.8
21.28
20.21
ug/l
0.03
90
854
599
5887
1.03
0.18
31.7
23.1
14.16
14.06
%
0.89
590
5768
47
434
1.08
0.18
3.4
3.7
0.93
0.85
%
0.83
47
414
72
762
0.94
0.17
3.6
3.5
1.21
1.22
mmol/l
0.57
62
633
13
110
1.18
0.17
1.2
1.8
3.81
4.72
mmol/24h
0.44
13
91
8
72
1.11
0.16
1.3
1.2
—
—
—
0
0
9
81
1.11
0.15
3.9
3.0
—
—
—
0
0
9
82
1.10
0.15
1.2
1.1
—
—
—
0
0
15
131
1.14
0.14
1.7
1.3
—
—
—
0
0
803
8091
0.98
0.14
33.8
24.6
88.70
88.25
umol/l
0.09
789
7852
72
684
1.05
0.14
3.1
2.8
121.23
124.32
g/l
0.57
65
667
34
315
1.08
0.13
2.7
3.1
167.43
497.32
mg/l
—
7
121
681
6852
0.99
0.09
5.9
4.9
1.99
2.09
mu/l
0.97
630
6038
35
330
1.06
0.09
1.4
1.2
—
—
—
0
0
11
97
1.13
0.08
3.4
2.8
—
—
—
0
0
7
67
1.04
0.08
1.1
1.1
—
65.78
—
0
5
768
7620
1.01
0.08
22.9
17.4
—
—
—
0
0
11
98
1.12
0.07
1.8
2.0
—
—
—
0
0
793
7958
0.99
0.07
30.6
22.8
139.25
139.43
mmol/l
1.09
777
7684
28
265
1.06
0.06
1.4
1.2
—
—
—
0
0
794
7963
0.99
0.06
30.9
23.0
4.03
4.02
mmol/l
0.75
777
7674
11
100
1.10
0.05
1.8
1.9
—
—
—
0
0
11
100
1.10
0.05
1.8
1.9
—
—
—
0
0
11
100
1.10
0.05
1.8
1.6
—
—
—
0
0
289
2861
1.01
0.04
2.3
2.3
—
—
—
0
0
267
2683
0.99
0.03
3.8
4.0
7.16
11.38
mg/mmol
1.19
172
1721
235
2361
0.99
0.02
1.9
1.8
1.38
1.27
mmol/l
1.25
201
1904
91
919
0.99
0.02
4.6
4.5
7.36
7.36
ph
0.14
74
636
258
2562
1.01
0.02
3.1
3.3
35.69
57.81
mg/l
2.08
172
1702
33
321
1.03
0.02
2.0
1.5
—
13.84
—
0
9
21
202
1.04
0.02
5.9
3.9
—
—
—
0
0
41
401
1.02
0.01
2.4
3.0
—
—
—
0
0
289
2893
1.00
0.01
5.4
5.6
5.23
6.53
ug/l
0.23
255
2507
15
154
0.97
0.00
1.6
1.5
—
—
—
0
0
17
170
1.00
0.00
1.7
1.6
3.00
44.68
iu/l
—
8
56
27
269
1.00
0.00
1.3
1.6
—
—
—
0
0
11
108
1.02
0.00
1.1
1.1
—
—
—
0
0
20
199
1.00
0.00
6.4
3.9
4.13
2.71
mmol/l
0.84
13
125
17
175
0.97
0.00
1.0
1.1
—
—
—
0
0
24
236
1.02
0.00
2.1
2.8
1.74
1.83
mg/l
0.19
18
203
14
140
1.00
0.00
1.8
1.3
—
—
—
0
0
54
538
1.00
0.00
1.7
1.5
—
—
—
0
0
27
271
0.99
0.00
4.3
3.7
24.40
33.20
mg/l
1.02
16
208
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
76.80
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.1
—
154.44
—
0
9
0
8
0.00
-0.00
0.0
1.1
—
0.02
—
0
8
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
5
58
0.86
-0.00
1.0
1.7
—
—
—
0
0
5
51
0.98
-0.00
1.0
1.2
114.40
98.57
pmol/l
—
5
51
9
95
0.95
-0.00
2.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
1.77
—
0
8
0
9
0.00
-0.00
0.0
1.8
—
—
—
0
0
8
79
1.01
-0.00
1.6
2.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.1
—
16.81
—
0
8

Mortality – FinRegistry

Association

Association between endpoint M13_SPINENTHES and mortality.

Females

Parameter HR [95% CI] p-value
M13_SPINENTHES 1.453 [1.13, 1.87] 0.004
Birth year 0.996 [0.99, 1.01] 0.406

During the follow-up period (1.1.1998 — 31.12.2019), 96 out of 699 females with M13_SPINENTHES died.

Males

Parameter HR [95% CI] p-value
M13_SPINENTHES 1.31 [1.04, 1.65] 0.022
Birth year 0.987 [0.98, 1.0] 0.008

During the follow-up period (1.1.1998 — 31.12.2019), 135 out of 629 males with M13_SPINENTHES died.

Mortality risk

Mortality risk for people of age

years, who have M13_SPINENTHES.

N-year risk Females Males
1 0.127% 0.208%
5 0.821% 1.478%
10 2.233% 3.758%
15 4.166% 7.268%
20 7.308% 12.053%

Relationships between endpoints

Index endpoint: M13_SPINENTHES – Spinal enthesopathy

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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