Benign neoplasm of male genital organs

CD2_BENIGN_MALE_GEN

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

only males

244368

2. Check conditions

None

244368

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D29
  • Cause of death: ICD-10 D29

2 out of 7 registries used, show all original rules.

694

4. Check minimum number of events

None

694

5. Include endpoints

831

6. Filter based on genotype QC (FinnGen only)

760

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF3
Parent code in ICD-10
D10-D36
Name in latin
Neoplasmata benigna organorum genitalium masculinorum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5564 - 5564
Only index persons 4801 - 4801
Unadjusted period prevalence (%)
Whole population 0.16 - 0.16
Only index persons 0.18 - 0.18
Median age at first event (years)
Whole population - - 52.91
Only index persons - - 50.02

-FinnGen-

Key figures

All Female Male
Number of individuals 760 - 760
Unadjusted period prevalence (%) 0.35 - 0.35
Median age at first event (years) 59.09 - 59.09

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
786
Matched controls
7860
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D29.1
ICD-10 Finland
Benign neoplasm: Prostate
446.5
259.0
246
8
D29.2
ICD-10 Finland
Benign neoplasm: Testis
1468.3
131.1
124
*
D29.4
ICD-10 Finland
Benign neoplasm: Scrotum
268.9
115.1
115
5
D29.3
ICD-10 Finland
Benign neoplasm: Epididymis
615.1
110.7
107
*
D40.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Testis
33.7
105.2
68
22
KFC00
NOMESCO Finland
Unilateral orchiectomy
17.2
73.4
62
39
D29.0
ICD-10 Finland
Benign neoplasm: Penis
+∞
55.9
53
*
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
6.0
47.8
91
169
22200
ICD-8 Finland
Benign neoplasm of male genital organs, Testis
+∞
27.2
26
*
22288
ICD-8 Finland
Benign neoplasm of male genital organs, Loco alio definito
+∞
26.2
25
*
KFD16
NOMESCO Finland
Partial excision of epididymis
31.2
25.2
33
11
2223A
ICD-9 Finland
Benign neoplasm of male genital organs, Epididymis
+∞
18.8
18
*
KFA00
NOMESCO Finland
Exploration of testis
22.4
18.3
26
12
D29.9
ICD-10 Finland
Benign neoplasm: Male genital organ, unspecified
+∞
17.8
17
*
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
3.8
17.2
53
145
2220A
ICD-9 Finland
Benign neoplasm of male genital organs, Testis
+∞
16.7
16
*
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
2.1
14.6
156
818
22210
ICD-8 Finland
Benign neoplasm of male genital organs, Penis
+∞
14.6
14
*
Y05
ICPC
Scrotum/testis sympt/compl other
4.7
14.3
33
72
C61
ICD-10 Finland
Malignant neoplasm of prostate
2.0
14.3
176
974
ZXC96
NOMESCO Finland
Robot assisted procedure
3.6
13.7
45
129
9061/3-C62.9
ICD-O-3
Seminoma, NOS, of testis, NOS
76.5
13.6
15
*
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.9
13.0
208
1253
KGB00
NOMESCO Finland
Biopsy of penis
23.0
12.9
18
8
N43.4
ICD-10 Finland
Spermatocele
3.7
12.7
41
116
XKD00
NOMESCO Finland
Uroflowmetry
1.8
12.6
239
1518
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
2.0
12.6
165
929
22280
ICD-8 Finland
Benign neoplasm of male genital organs, Scroti
+∞
12.5
12
*
D29.7
ICD-10 Finland
Benign neoplasm: Other male genital organs
+∞
12.5
12
*
KEC01
NOMESCO Finland
Percutaneous endoscopic radical prostatectomy
3.2
12.4
49
158
N45.9
ICD-10 Finland
Orchitis, epididymitis and epididymo-orchitis without abscess
3.4
12.4
44
133
C62.11
ICD-10 Finland
Malignant tumor of the descending testicle, seminoma
47.4
11.9
14
*
UKC02
NOMESCO Finland
Cystoscopy
1.8
11.3
197
1213
N40
ICD-10 Finland
Hyperplasia of prostate
1.7
11.3
357
2600
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.9
11.0
149
845
J01DB01
ATC
cefalexin; oral
1.8
10.9
619
5256
XJH00
NOMESCO Finland
Transanal ultrasonography
2.2
10.2
97
483
NK6AN
NOMESCO Finland
Total body bone isotope imaging
3.1
9.0
37
123
7511
FHL
Orchidectomy (unilateral), also includes funicularectomy
12.9
8.4
14
11
7501
FHL
Testicular exploration (includes removal of biopsy, detorsion or appendix test)
12.9
8.4
14
11
22299
ICD-8 Finland
Benign neoplasm of male genital organs, Unspecified site
+∞
8.3
8
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.1
8.3
83
422
G04CA02
ATC
tamsulosin; oral
1.5
8.0
355
2735
D40.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other male genital organs
22.3
8.0
11
5
J01MA02
ATC
ciprofloxacin; systemic
1.6
8.0
324
2447
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
7.6
200
1363
KFD96
NOMESCO Finland
Other excision or ligature of scrotal organs
80.8
7.4
8
*
C05AA08
ATC
fluocortolone; rectal, topical
1.9
7.4
101
573
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
7.3
218
1531
KFW96
NOMESCO Finland
Other operation on scrotum or scrotal organs
20.2
7.1
10
5
N50.8
ICD-10 Finland
Other specified disorders of male genital organs
4.3
7.0
18
43
S18
ICPC
Laceration/cut
1.5
6.9
361
2855
KFH50
NOMESCO Finland
Insertion of prosthetic replacement for testis
40.4
6.8
8
*
M02AA10
ATC
ketoprofen; topical
1.8
6.7
107
637
KFD70
NOMESCO Finland
Excision of lesion of skin of scrotum
26.9
6.2
8
*
KFD30
NOMESCO Finland
Operation for spermatocele
4.0
6.2
17
43

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
46
28
17.39
55.14
3.8
2.3
27.34
63.84
u/l
—
7
5
318
2283
1.66
10.42
2.3
2.3
—
—
—
0
0
579
4852
1.73
10.27
7.0
5.7
2.64
2.88
ug/l
0.20
513
4375
512
4279
1.56
7.96
5.5
4.4
—
2.94
—
0
8
488
4058
1.53
7.57
5.6
4.5
129.10
283.21
e6/l
—
10
72
173
1166
1.62
6.82
2.8
2.4
13.19
13.76
nmol/l
0.40
151
1047
430
3572
1.45
6.08
17.8
19.2
1.33
1.35
inr
0.30
364
3023
430
3580
1.44
5.96
7.2
7.7
11.91
13.25
umol/l
2.44
417
3440
103
643
1.69
5.42
5.6
5.2
7.33
7.35
ph
0.56
69
488
366
3000
1.41
5.30
2.2
2.3
94.40
92.67
pmol/l
0.27
207
1760
12
18
6.75
5.27
1.8
4.3
3.08
5.66
ug/l
1.08
12
18
131
877
1.59
5.23
1.3
1.4
—
—
—
0
0
373
3082
1.40
5.09
7.7
8.2
1.20
1.20
mmol/l
0.99
338
2862
407
3419
1.39
5.01
8.4
9.0
1.20
1.20
mmol/l
0.22
341
2955
559
4963
1.44
4.97
9.6
9.3
78.47
81.78
u/l
0.93
531
4734
43
208
2.13
4.94
1.7
1.4
7.95
5.85
u/l
0.51
30
166
477
4135
1.39
4.75
5.5
6.2
6.69
6.94
mmol/l
2.20
458
3990
298
2398
1.39
4.64
4.8
4.0
—
0.78
—
0
9
364
3050
1.36
4.32
2.8
3.1
—
—
estimate
—
0
0
679
6318
1.55
4.27
25.2
24.1
4.01
4.04
mmol/l
1.68
666
6202
310
2539
1.36
4.23
2.4
2.3
75.79
74.66
nmol/l
0.31
267
2264
591
5361
1.41
4.18
4.4
4.2
1.91
2.03
mu/l
1.30
528
4876
677
6303
1.53
4.16
25.1
23.9
139.66
139.64
mmol/l
0.08
664
6192
118
822
1.51
3.93
2.8
3.4
4.91
5.36
e9/l
0.21
86
708
659
6130
1.46
3.78
20.8
19.5
29.97
29.96
mg/l
0.00
568
5204
85
558
1.59
3.69
2.2
2.2
0.00
0.00
estimate
-0.00
12
114
266
2166
1.34
3.66
3.3
3.0
66.51
96.72
u/l
0.38
251
2041
692
6534
1.49
3.32
27.6
25.4
91.54
91.14
umol/l
0.11
680
6466
52
311
1.72
3.25
2.1
2.3
0.00
2.81
estimate
—
8
90
318
2698
1.30
3.17
3.1
3.1
180.67
195.78
ug/l
0.46
290
2495
359
3097
1.29
3.15
6.6
7.0
9.36
9.35
%
0.02
332
2924
115
834
1.44
3.14
1.5
1.3
—
—
—
0
0
310
2626
1.30
3.12
4.0
3.3
6.14
6.18
ph
0.32
186
1514
84
574
1.52
3.08
1.3
1.4
—
—
—
0
0
357
3089
1.29
3.02
6.4
6.9
2.71
2.90
%
0.95
330
2917
357
3090
1.28
3.01
6.6
7.0
0.64
0.64
%
0.03
330
2924
357
3092
1.28
2.99
6.1
6.8
59.59
58.74
%
0.71
331
2966
65
424
1.58
2.93
3.1
2.8
—
—
—
0
0
266
2226
1.29
2.89
3.2
3.8
33.09
38.37
u/l
1.29
247
2107
17
71
2.43
2.81
2.3
1.3
9.55
11.20
iu/l
0.24
11
55
274
2310
1.29
2.79
6.6
6.6
—
—
—
0
0
643
6039
1.36
2.76
5.4
5.4
4.25
4.31
mmol/l
0.77
585
5623
336
2912
1.27
2.72
3.9
3.3
0.69
0.78
ug/l
1.59
231
1926
697
6637
1.44
2.72
31.4
28.7
229.64
230.32
e9/l
0.10
684
6496
697
6639
1.44
2.69
31.3
28.6
91.21
91.56
fl
1.24
689
6557
360
3150
1.26
2.68
6.5
7.0
24.82
25.46
%
0.52
339
3005
697
6641
1.44
2.67
31.4
28.6
4.56
4.56
e12/l
0.06
679
6483
697
6641
1.44
2.67
31.2
28.5
30.47
30.63
pg
1.52
690
6558
697
6641
1.44
2.67
31.9
29.5
41.08
41.73
%
0.44
689
6551
697
6642
1.44
2.66
31.6
28.9
137.85
138.49
g/l
0.44
690
6560
697
6643
1.43
2.65
31.4
28.7
7.00
6.99
e9/l
0.03
681
6487
473
4279
1.26
2.63
3.8
3.7
52.77
60.68
u/l
1.31
439
4029
52
333
1.60
2.56
5.0
4.3
24.00
24.92
mmol/l
1.76
45
309
281
2408
1.26
2.45
4.2
3.7
40.87
131.96
e6/l
1.85
225
1902
627
5898
1.31
2.42
5.8
5.4
6.03
6.15
mmol/l
1.81
559
5376
276
2363
1.26
2.42
4.6
4.9
—
—
—
0
0
258
2192
1.26
2.41
2.5
2.3
337.54
279.85
u/l
0.24
246
2078
636
6000
1.31
2.36
5.5
5.3
1.31
1.29
mmol/l
0.64
579
5538
385
3430
1.24
2.34
6.2
6.9
0.19
0.21
e9/l
1.00
337
2997
367
3255
1.24
2.32
4.2
3.7
0.00
0.00
estimate
-0.00
79
714
371
3296
1.24
2.31
4.3
3.7
0.00
2.44
estimate
0.50
78
718
371
3301
1.23
2.26
4.3
3.7
0.00
0.46
estimate
0.51
72
657
46
296
1.59
2.25
1.5
1.7
—
—
—
0
0
379
3386
1.23
2.20
6.1
6.8
1.71
1.92
e9/l
1.77
333
2978
29
166
1.78
2.18
4.9
5.1
2.98
2.21
mmol/l
0.51
20
109
459
4187
1.23
2.17
3.3
3.3
14.98
14.95
pmol/l
0.07
413
3780
675
6448
1.33
2.09
14.0
13.0
28.04
29.30
u/l
0.82
648
6276
259
2233
1.24
2.08
2.8
2.9
—
—
—
0
0
372
3334
1.22
2.05
6.1
6.6
0.63
0.64
e9/l
0.22
323
2853
193
1613
1.26
2.04
3.5
3.3
—
—
—
0
0
372
3339
1.22
2.01
6.1
6.6
0.04
0.04
e9/l
0.88
321
2867
58
404
1.47
2.00
2.0
2.0
37.15
39.26
nmol/l
0.30
58
388
296
2597
1.22
2.00
4.9
4.2
53.06
130.13
e6/l
1.49
229
1969
16
78
2.07
1.92
1.7
1.4
113.16
166.56
pmol/l
1.41
16
78
238
2051
1.23
1.90
1.7
1.8
18.45
18.92
nmol/l
0.20
192
1744
406
3690
1.21
1.88
9.9
10.3
4.46
4.39
e9/l
0.21
361
3202
97
750
1.33
1.85
1.6
1.7
—
—
—
0
0
644
6139
1.27
1.84
6.1
6.0
2.48
2.54
mmol/l
0.91
588
5680
238
2061
1.22
1.80
4.0
3.6
0.91
0.47
e6/l
0.58
178
1572
118
942
1.30
1.80
2.0
1.8
—
—
—
0
0
40
264
1.54
1.80
2.0
1.9
—
—
—
0
0
317
2825
1.20
1.79
4.6
4.3
37.07
79.02
ng/l
1.11
252
2216
5
138
0.36
1.75
1.2
1.4
—
—
—
0
0
138
1128
1.27
1.75
2.8
3.0
22.29
23.65
%
0.58
127
1058
20
110
1.84
1.74
2.1
2.4
1.48
1.66
g/24h
0.10
13
65
609
5784
1.23
1.70
4.6
4.5
1.30
1.34
mmol/l
0.63
543
5309
153
1275
1.25
1.65
1.8
1.8
1133.59
1157.67
nmol/l
0.09
107
986
218
1889
1.21
1.62
7.0
6.6
—
—
—
0
0
17
91
1.89
1.61
2.6
2.6
—
—
—
0
0
283
2517
1.19
1.59
1.9
2.0
1.38
1.39
mmol/l
0.08
244
2078
199
1714
1.22
1.57
3.4
2.8
2.36
2.96
e6/l
1.07
184
1553
146
1218
1.24
1.56
2.7
3.0
2.16
2.20
g/l
0.34
132
1137
83
645
1.32
1.55
3.0
2.7
37.03
41.02
u/l
0.22
74
554
41
282
1.48
1.55
2.4
2.9
9.40
11.24
g/l
1.74
33
255
155
1303
1.24
1.55
3.6
3.3
1.01
0.88
e6/l
0.20
88
760
268
2378
1.19
1.54
3.6
3.5
1976.22
1898.50
ng/l
0.08
227
2094
71
540
1.35
1.54
3.7
2.8
—
—
—
0
0
78
602
1.33
1.53
5.0
4.0
7.42
7.41
ph
0.15
60
511
91
719
1.30
1.52
1.7
1.8
—
—
—
0
0
63
473
1.36
1.49
1.4
1.6
—
—
—
0
0
55
404
1.39
1.48
2.0
2.0
1.47
1.48
ug/l
0.01
44
361
107
1307
0.79
1.48
3.9
3.4
2.46
2.45
mmol/l
0.41
98
1178
30
195
1.56
1.47
3.7
4.2
—
—
—
0
0
341
3099
1.18
1.47
5.5
6.2
34.92
34.87
g/l
0.05
312
2911
79
616
1.31
1.46
4.9
4.0
4.96
5.13
kpa
1.19
74
593
46
329
1.42
1.44
2.5
2.4
—
—
—
0
0
6
22
2.74
1.43
7.0
7.2
10.50
7.45
%
—
6
22
6
22
2.74
1.43
3.5
3.6
39.83
49.05
%
—
6
22
213
1864
1.20
1.42
2.4
2.3
3.01
2.87
mg/l
0.35
181
1612
57
425
1.37
1.41
5.4
4.2
—
—
—
0
0
215
1884
1.19
1.41
4.3
3.8
0.00
0.01
estimate
0.96
74
627
39
272
1.46
1.40
2.8
3.4
1.48
2.41
ratio
1.32
27
157
226
1996
1.19
1.35
5.4
4.9
7.39
7.40
ph
0.45
158
1476
194
1693
1.19
1.33
2.7
2.8
—
—
—
0
0
152
1297
1.21
1.32
2.7
3.0
12.29
13.00
umol/l
0.57
140
1217
85
681
1.28
1.30
3.4
3.0
66.11
66.14
g/l
0.01
73
634
16
92
1.75
1.25
7.2
5.4
—
—
—
0
0
8
36
2.23
1.24
2.3
1.3
0.14
0.16
nmol/l
—
8
22
166
1444
1.19
1.18
4.0
4.1
188.59
451.58
ng/l
1.55
144
1235
144
1239
1.20
1.16
3.8
3.4
1.19
0.58
e6/l
0.70
80
694
44
327
1.37
1.15
1.2
1.2
—
—
—
0
0
5
21
2.39
1.09
1.0
1.0
—
—
—
0
0
11
59
1.88
1.07
3.4
2.8
7.73
8.39
mmol/l
0.38
11
59
608
5859
1.17
1.04
7.6
7.0
39.91
40.27
mmol/mol
0.44
544
5469
9
46
1.97
1.04
2.9
2.7
—
—
—
0
0
89
740
1.23
1.02
1.5
1.4
—
—
—
0
0
44
335
1.33
1.01
2.8
2.4
1141.13
572.16
ug/l
0.28
39
327
219
1978
1.15
0.97
3.3
3.2
371.07
378.00
umol/l
0.55
195
1739
7
36
1.95
0.97
1.9
1.9
82.43
127.95
ng/l
—
7
36
98
830
1.21
0.95
3.3
4.3
7.37
7.38
ph
0.04
62
509
15
93
1.62
0.94
1.4
2.4
—
—
—
0
0
15
93
1.62
0.94
7.7
4.9
58.25
57.46
%
—
10
87
96
813
1.21
0.93
2.8
3.3
9.69
10.36
umol/l
0.09
83
742
27
194
1.41
0.89
4.9
3.0
—
—
—
0
0
8
43
1.87
0.87
1.4
1.1
83.63
101.49
pmol/l
—
8
43
94
801
1.20
0.87
3.3
4.3
1.83
1.74
mmol/l
0.09
80
675
271
2501
1.13
0.86
4.3
3.7
0.00
0.02
estimate
1.32
68
608
21
145
1.46
0.85
3.2
3.1
61.49
57.44
%
0.67
21
145
35
266
1.33
0.84
1.1
1.3
—
—
—
0
0
208
2278
0.88
0.83
3.3
3.3
—
—
—
0
0
21
146
1.45
0.83
3.5
2.0
1.00
0.89
nmol/l
0.38
16
129
59
482
1.24
0.82
4.8
5.2
103.37
116.11
ng/l
0.34
52
426
13
81
1.62
0.81
1.1
1.4
8.57
6.78
u/ml
—
7
45
8
47
1.71
0.81
1.0
1.7
—
—
—
0
0
41
324
1.28
0.76
1.1
1.2
—
—
—
0
0
26
193
1.36
0.74
3.6
3.6
—
—
—
0
0
37
290
1.29
0.73
1.2
1.2
—
—
—
0
0
7
38
1.85
0.73
2.1
2.3
—
—
—
0
0
102
891
1.17
0.73
1.8
1.8
—
—
—
0
0
5
25
2.01
0.72
1.4
1.1
—
—
—
0
0
5
25
2.01
0.72
1.0
1.0
—
—
—
0
0
17
117
1.46
0.72
3.2
3.1
5.11
4.42
e9/l
0.36
17
117
12
77
1.57
0.69
1.0
1.2
—
—
—
0
0
5
27
1.86
0.68
4.8
1.6
—
—
—
0
0
114
1011
1.15
0.67
2.5
2.6
1.67
1.77
%
0.75
102
914
5
28
1.79
0.66
1.4
1.7
—
—
—
0
0
5
28
1.79
0.66
1.8
1.3
12.60
9.43
mm/h
—
5
28
162
1473
1.13
0.66
3.4
3.1
571.01
574.37
mosm/kgh2o
0.07
144
1282
95
834
1.16
0.65
1.5
1.6
—
—
—
0
0
5
29
1.73
0.64
1.0
1.0
—
—
—
0
0
13
87
1.50
0.63
1.2
1.1
—
—
—
0
0
57
673
0.83
0.63
1.6
1.5
—
—
—
0
0
27
209
1.30
0.61
5.0
2.7
—
—
—
0
0
0
21
0.00
0.60
0.0
1.3
—
12.20
—
0
21
90
793
1.15
0.59
2.3
2.7
68.27
67.18
e9/l
0.13
72
609
0
22
0.00
0.59
0.0
2.0
—
3.11
—
0
22
27
210
1.30
0.59
4.9
2.8
—
—
—
0
0
19
140
1.37
0.59
1.1
1.3
—
—
—
0
0
191
1767
1.11
0.58
4.0
3.3
0.02
0.07
estimate
0.54
63
547
7
116
0.60
0.58
1.0
1.5
—
—
—
0
0
15
207
0.72
0.57
1.4
1.2
—
—
—
0
0
27
212
1.28
0.56
4.9
2.8
—
—
—
0
0
27
212
1.28
0.56
4.9
2.8
—
—
—
0
0
9
60
1.51
0.54
1.1
1.1
—
—
—
0
0
50
424
1.19
0.53
1.9
1.9
1.05
1.51
g/l
0.86
43
396
162
1495
1.11
0.52
5.1
3.9
1.02
1.02
kg/l
0.89
131
1018
45
379
1.20
0.52
2.6
2.5
9.26
18.60
au/ml
—
5
37
140
1285
1.11
0.50
4.0
3.7
0.80
0.82
mmol/l
1.44
130
1225
25
312
0.79
0.49
4.2
4.0
346.90
4326.52
u/ml
0.66
20
265
92
825
1.13
0.49
3.4
4.3
5.81
5.84
kpa
0.11
92
800
159
1471
1.10
0.49
1.8
1.8
101538889.62
17441331.46
pmol/l
0.60
130
1227
20
154
1.31
0.49
1.5
1.8
—
—
—
0
0
29
235
1.24
0.48
2.1
1.7
—
—
—
0
0
50
429
1.18
0.48
1.3
1.9
1.75
1.52
g/l
0.86
40
383
85
760
1.13
0.48
1.3
1.3
366.67
353.47
titre
0.05
12
147
14
188
0.74
0.47
2.1
2.6
124.38
130.07
g/l
—
8
149
12
85
1.42
0.47
6.2
4.7
—
—
—
0
0
97
877
1.12
0.46
1.3
1.3
65.58
34.60
iu/ml
0.47
25
244
20
156
1.29
0.45
3.3
3.8
35.07
32.41
mg/l
0.06
12
116
14
186
0.75
0.44
1.0
1.1
—
—
—
0
0
12
87
1.39
0.42
1.3
1.2
—
—
—
0
0
5
32
1.57
0.42
1.8
2.0
435.60
1621.72
u/ml
—
5
32
22
176
1.26
0.42
1.9
1.6
—
—
—
0
0
21
167
1.26
0.42
4.0
3.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
1.16
—
0
15
123
1137
1.10
0.40
1.3
1.2
1.02
1.21
u/ml
0.29
29
316
68
608
1.13
0.40
4.7
5.0
0.08
0.14
%
0.38
24
206
0
19
0.00
0.39
0.0
7.9
—
5.20
—
0
19
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
83
753
1.11
0.39
8.4
11.2
—
—
—
0
0
38
326
1.17
0.39
3.8
3.1
24.83
24.64
mmol/l
0.12
38
321
17
214
0.79
0.38
3.1
2.4
101.22
117.36
ug/min
—
9
126
5
36
1.39
0.38
4.2
1.3
40.48
39.21
g/l
—
5
36
82
745
1.11
0.38
3.1
2.6
0.21
0.20
g/l
0.18
76
682
68
612
1.12
0.37
4.9
4.6
1.04
0.63
%
0.54
25
229
36
417
0.86
0.36
1.2
1.4
—
—
—
0
0
5
78
0.64
0.35
1.2
1.6
33.00
43.79
ng/l
—
5
78
25
298
0.83
0.35
1.1
1.1
—
—
—
0
0
6
45
1.34
0.34
2.2
2.3
24.67
16.18
%
—
6
45
23
191
1.21
0.33
1.2
1.4
1.15
1.16
g/l
0.09
23
184
10
74
1.36
0.32
1.0
1.2
—
—
—
0
0
11
83
1.33
0.32
1.2
1.3
—
—
—
0
0
67
609
1.11
0.32
5.1
5.2
0.00
0.10
%
1.49
21
191
15
119
1.27
0.32
3.2
4.1
6.00
12.19
pmol/l
4.08
15
119
7
54
1.30
0.30
2.6
1.6
—
—
—
0
0
21
175
1.21
0.30
3.5
4.7
—
—
—
0
0
44
392
1.13
0.29
1.5
1.2
—
—
—
0
0
23
195
1.18
0.28
1.0
1.1
1.45
1.43
g/l
0.17
23
195
19
158
1.21
0.28
1.3
1.2
—
—
—
0
0
42
375
1.13
0.28
2.7
3.8
25.00
25.05
mmol/l
0.03
42
358
9
116
0.77
0.27
1.1
1.6
—
—
—
0
0
8
64
1.25
0.27
1.0
1.2
—
—
—
0
0
15
122
1.23
0.27
2.3
2.6
—
—
—
0
0
59
539
1.10
0.27
3.1
2.8
10.53
11.50
g/l
0.96
51
497
8
66
1.21
0.26
2.4
2.6
—
—
—
0
0
17
141
1.21
0.26
1.2
1.1
—
—
—
0
0
22
188
1.18
0.25
1.2
1.3
0.22
0.24
g/l
0.64
22
180
9
73
1.24
0.25
1.3
1.2
—
—
—
0
0
24
207
1.16
0.25
1.1
1.2
0.95
0.94
g/l
0.03
24
207
69
640
1.09
0.24
4.7
4.9
1.00
0.90
%
0.14
25
238
73
679
1.08
0.23
3.1
3.3
5.03
4.54
kpa
0.60
73
659
23
199
1.16
0.23
5.7
3.6
7.00
1.87
index
0.51
13
118
56
608
0.91
0.23
1.5
1.4
—
—
—
0
0
65
604
1.08
0.22
1.8
2.3
386.98
378.24
nmol/l
0.14
60
556
5
41
1.22
0.22
1.4
1.0
—
—
—
0
0
5
41
1.22
0.22
4.6
4.3
844.20
93.95
nmol/l
—
5
41
116
1102
1.06
0.22
7.6
7.5
1.06
1.02
mmol/l
0.79
107
1047
19
220
0.86
0.21
3.5
3.2
7.87
7.90
kpa
0.03
19
214
0
11
0.00
0.21
0.0
1.0
—
18.83
—
0
6
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
70.40
—
0
10
0
10
0.00
0.21
0.0
1.0
—
16.63
—
0
10
8
101
0.79
0.21
1.4
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.8
—
119.67
—
0
12
5
43
1.16
0.21
1.0
1.1
263.00
310.82
mg/l
—
5
38
0
13
0.00
0.21
0.0
2.0
—
11.33
—
0
6
107
1016
1.06
0.21
7.1
9.6
1.12
0.71
mmol/l
0.52
92
832
108
1026
1.06
0.20
7.1
9.6
5.00
5.10
kpa
0.57
101
991
10
80
1.25
0.20
1.1
1.2
—
—
—
0
0
31
278
1.12
0.20
1.4
1.3
—
—
—
0
0
31
278
1.12
0.20
4.1
4.1
317.52
276.09
mg/l
0.16
23
142
0
14
0.00
0.20
0.0
6.6
—
8.56
—
0
14
108
1027
1.06
0.20
7.0
9.6
11.55
11.99
kpa
0.44
103
995
45
488
0.92
0.19
1.2
1.4
—
—
—
0
0
13
153
0.85
0.18
14.4
3.8
—
—
—
0
0
7
61
1.15
0.17
3.6
2.1
33.37
36.60
%
—
7
61
7
62
1.13
0.17
4.0
2.9
16.71
16.10
%
—
7
62
446
4526
0.97
0.17
4.4
4.6
—
7770.92
—
0
13
50
535
0.93
0.16
3.7
5.6
—
—
—
0
0
21
235
0.89
0.16
1.2
1.1
27.61
142.75
u/ml
—
9
79
501
4949
1.03
0.16
24.2
23.8
13.82
13.77
%
0.27
495
4888
49
458
1.07
0.15
2.4
2.6
5.97
6.02
ph
0.15
38
330
6
76
0.79
0.15
1.5
1.2
—
—
—
0
0
36
389
0.92
0.15
1.6
1.7
3.29
3.52
mmol/l
0.51
27
283
289
2833
1.03
0.15
12.5
12.7
0.00
0.00
e9/l
0.68
238
2321
7
90
0.78
0.14
1.0
1.2
—
—
—
0
0
106
1020
1.05
0.14
7.3
9.7
7.43
7.41
ph
1.56
65
564
139
1346
1.04
0.14
1.6
1.7
1.25
1.59
mg/l
0.94
110
1059
13
149
0.87
0.13
1.2
1.4
—
—
—
0
0
62
652
0.95
0.13
2.7
3.1
288.57
232.84
ng/l
0.31
56
594
12
138
0.87
0.13
1.2
1.5
1622.25
1773.16
e6/l
0.07
12
98
19
171
1.11
0.12
3.0
9.8
104.58
105.56
mmol/l
0.48
19
153
19
171
1.11
0.12
3.0
9.8
10.74
11.83
mmol/l
0.76
19
153
86
827
1.04
0.12
7.2
8.9
11.27
11.28
mmol/l
0.00
80
795
70
730
0.95
0.11
2.0
2.5
9.49
8.49
ug/l
0.14
56
661
14
124
1.13
0.11
1.1
1.1
—
3.44
—
0
9
14
124
1.13
0.11
1.1
1.1
—
—
—
0
0
235
2394
0.97
0.11
4.1
3.7
56.72
63.39
mg/l
0.14
162
1711
20
182
1.10
0.11
2.8
3.8
1.73
1.61
mmol/l
0.28
20
175
74
770
0.96
0.11
4.2
4.5
4.19
31.63
ug/l
1.72
64
642
111
1077
1.04
0.10
1.7
1.5
2.65
2.89
g/l
0.43
67
690
116
1127
1.03
0.10
1.9
2.3
—
—
—
0
0
20
183
1.10
0.10
2.5
1.9
14.12
12.45
mg/l
0.37
20
169
14
125
1.12
0.10
1.1
1.2
12.00
2.72
u/ml
—
5
13
62
646
0.96
0.10
3.0
2.8
146.80
157.37
ug/g
0.14
48
541
5
44
1.14
0.10
1.0
1.2
34.00
50.15
mg/l
—
5
36
16
176
0.91
0.09
2.9
2.8
16.94
16.30
%
0.29
16
170
16
145
1.11
0.09
1.4
1.7
18.26
18.37
ug/l
0.01
16
140
84
814
1.04
0.09
1.3
1.3
2.32
12.99
u/ml
3.27
28
300
6
55
1.09
0.09
2.2
1.5
81.67
90.40
umol/l
—
6
55
6
55
1.09
0.09
1.2
1.3
—
—
—
0
0
6
58
1.03
0.08
1.0
1.4
7.39
7.39
ph
—
6
44
10
113
0.88
0.08
1.3
1.5
—
—
—
0
0
14
154
0.91
0.08
1.4
1.4
—
—
—
0
0
12
133
0.90
0.07
1.9
2.3
—
—
—
0
0
6
70
0.86
0.07
1.2
1.2
—
—
—
0
0
181
1781
1.02
0.07
1.3
1.3
—
—
—
0
0
242
2451
0.98
0.07
4.8
4.5
11.63
10.83
mg/mmol
0.07
160
1705
7
84
0.83
0.07
1.3
2.9
953.29
1268.95
mg
—
7
84
8
94
0.85
0.06
1.0
1.2
—
—
—
0
0
8
94
0.85
0.06
1.0
1.2
—
—
—
0
0
21
197
1.07
0.06
18.5
13.5
—
—
—
0
0
21
197
1.07
0.06
1.1
1.2
—
1.52
—
0
13
54
523
1.03
0.06
5.2
3.8
—
—
—
0
0
215
2173
0.99
0.05
3.8
3.8
2.34
2.33
mmol/l
0.74
191
1978
34
327
1.04
0.05
1.1
1.3
861.40
293.36
u/ml
0.42
29
299
25
260
0.96
0.03
2.3
3.8
4.07
4.51
pmol/l
1.21
20
234
16
169
0.95
0.03
1.2
1.2
—
—
—
0
0
21
219
0.96
0.03
1.7
1.8
20.00
8.38
iu/ml
—
5
54
12
112
1.07
0.03
1.4
1.6
—
—
—
0
0
12
112
1.07
0.03
1.4
1.6
—
—
—
0
0
12
112
1.07
0.03
1.4
1.6
—
—
—
0
0
12
112
1.07
0.03
1.4
1.6
—
—
—
0
0
13
122
1.07
0.02
1.1
1.1
—
—
—
0
0
14
132
1.06
0.02
2.2
1.8
1.65
1.70
mmol/l
0.11
14
127
27
262
1.03
0.02
1.4
2.1
20.14
21.79
s
0.97
21
245
251
2521
0.99
0.01
4.2
3.7
8.16
8.46
mmol/l
0.48
202
2143
36
353
1.02
0.01
1.9
1.9
0.39
0.34
mg/l
0.17
19
191
15
144
1.04
0.00
1.2
1.0
—
—
—
0
0
16
158
1.01
0.00
2.9
4.0
7.73
7.68
mmol/l
0.02
16
152
138
1385
1.00
0.00
5.0
5.1
—
—
—
0
0
11
109
1.01
0.00
5.4
5.9
342.73
345.44
umol/l
0.03
11
101
18
181
0.99
0.00
1.4
1.6
250.40
255.47
ug/g
—
10
117
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
4.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.6
—
—
—
0
0
33
330
1.00
-0.00
1.7
1.3
—
9.79
—
0
11
5
54
0.93
-0.00
3.6
1.1
182.80
142.92
nmol/l
—
5
54
8
86
0.93
-0.00
1.0
1.2
1.44
1.60
nmol/l
—
8
77
0
7
0.00
-0.00
0.0
1.0
—
0.05
—
0
7
7
79
0.89
-0.00
3.1
1.5
9.10
10.67
%
—
7
79
0
7
0.00
-0.00
0.0
1.1
—
408.00
—
0
7
6
61
0.98
-0.00
1.3
1.1
—
—
—
0
0
6
59
1.02
-0.00
1.2
1.0
869.33
646.61
ng/l
—
6
36
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
6
66
0.91
-0.00
1.2
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
7
69
1.01
-0.00
1.6
1.3
—
—
nmol/l
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
2.37
—
0
9
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
6
59
1.02
-0.00
1.2
1.0
351.67
283.22
ng/l
—
6
37
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_MALE_GEN and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_MALE_GEN 1.301 [1.15, 1.47] < 0.001
Birth year 0.986 [0.98, 1.0] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 965 out of 3809 males with CD2_BENIGN_MALE_GEN died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_MALE_GEN.

N-year risk Females Males
1 No data 0.238%
5 No data 1.447%
10 No data 3.479%
15 No data 6.681%
20 No data 11.102%

Relationships between endpoints

Index endpoint: CD2_BENIGN_MALE_GEN – Benign neoplasm of male genital organs

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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