Complications of anaesthesia during the puerperium

O15_PUERP_ANEST_COMPL

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule only females	313377
2. Check conditions None	313377
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — O89 Cause of death: ICD-10 — O89 2 out of 7 registries used, show all original rules.	139
4. Check minimum number of events None	139
5. Include endpoints None	139
6. Filter based on genotype QC (FinnGen only)	130

Control definitions (FinnGen only)

Control exclude: O15_COMPLIC_PUERP

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF3
Parent code in ICD-10: O85-O92
Name in latin: Complicationes anaesthesiae in puerperio

NAME	O15_PUERP_ANEST_COMPL
CONTROL_EXCLUDE	O15_COMPLIC_PUERP
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX	2
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	O89
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	O89
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Complications of anaesthesia during the puerperium based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	926	926	-
Only index persons	924	924	-
Unadjusted period prevalence (%)
Whole population	0.03	0.03	-
Only index persons	0.03	0.03	-
Median age at first event (years)
Whole population	-	29.67	-
Only index persons	-	29.66	-

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	130	130	-
Unadjusted period prevalence (%)	0.05	0.05	-
Median age at first event (years)	30.46	30.46	-

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
137: Matched controls
1370

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

TAB22

NOMESCO Finland

Stoppin epidural fluid escape with coagulated blood

203.2

174.6

O89.4

ICD-10 Finland

Spinal and epidural anaesthesia-induced headache during the puerperium

+∞

168.9

125

MCA10

NOMESCO Finland

Lower uterine segment caesarean section

3.8

12.9

241

O34.2

ICD-10 Finland

Maternal care due to uterine scar from previous surgery

3.9

9.8

112

O82.0

ICD-10 Finland

Delivery by elective caesarean section

3.7

7.9

O47.0

ICD-10 Finland

False labour before 37 completed weeks of gestation

2.9

7.2

199

G97.0

ICD-10 Finland

Cerebrospinal fluid leak from spinal puncture

10.1

7.0

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

464

1.82

2.94

5.7

1.21

1.22

mmol/l

0.64

407

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

4.11

2.83

1.1

1.0

—

(40758990) Choriogonadotropin.beta subunit [Mass/volume] in Serum or Plasma

8.59

2.77

1.6

1.0

53.00

59.33

ug/l

—

(3045424) Erythrocytes [Presence] in Urine

2.64

2.73

2.3

1.8

0.00

estimate

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

421

1.76

2.61

1.9

1.8

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

601

1.74

2.57

3.2

2.7

—

estimate

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

302

1.79

2.49

2.4

3.0

8.42

11.71

ng/l

1.05

125

(3019225) pH of Specimen

2.29

2.41

3.7

4.3

7.18

7.34

0.35

(3002179) Metamyelocytes/Leukocytes in Blood

2.26

2.35

4.2

4.1

0.80

0.73

—

(3029937) Albumin [Presence] in Urine by Test strip

354

1.70

2.25

3.6

3.4

0.00

estimate

-0.00

149

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

100

2.04

1.97

2.0

1.8

—

(3016244) Insulin [Units/volume] in Serum or Plasma

4.67

1.96

1.0

3.3

13.16

17.49

mu/l

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

497

1.54

1.69

2.1

2.2

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

236

1.65

1.67

1.7

1.6

872.21

1021.70

mu/l

0.64

196

(3037467) Urinalysis macro (dipstick) panel - Urine

100

859

1.61

1.66

4.9

4.1

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

2.51

1.56

9.3

9.5

0.66

0.68

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

3.42

1.53

1.4

1.1

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

3.42

1.53

1.4

1.1

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

3.42

1.53

1.2

1.1

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

3.42

1.53

2.0

1.9

—

(3044290) Cell count panel - Cerebral spinal fluid

2.58

1.47

2.6

1.3

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

135

1.75

1.47

1.4

—

(3027008) Opiates [Presence] in Urine

121

0.39

1.46

2.6

1.5

—

(3000764) Benzodiazepines [Presence] in Urine

122

0.39

1.46

2.6

1.5

—

(3028300) Cannabinoids [Presence] in Urine

122

0.39

1.46

2.6

1.5

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

3.20

1.45

1.0

1.2

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

3.20

1.45

1.0

1.2

—

(3019832) Treponema pallidum Ab [Presence] in Serum

371

1.50

1.41

2.1

1.8

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

590

1.46

1.39

4.6

4.1

6.24

6.08

mmol/l

0.24

527

(40764999) Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)/1.73 sq M

123

1131

1.86

1.38

9.1

9.2

96.95

95.83

ml/min/173m2

0.32

111

1011

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

116

1050

1.68

1.38

4.8

4.9

14.28

14.18

pmol/l

0.17

110

1003

(3016879) Cocaine [Presence] in Urine

117

0.41

1.32

2.6

1.5

—

(3012413) Glucose [Moles/volume] in Serum or Plasma --2 hours post meal

2.57

1.32

2.0

1.5

9.08

7.63

mmol/l

—

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

116

1.74

1.29

3.6

3.5

31.09

32.68

0.34

(3004616) Nuclear Ab [Presence] in Serum

2.84

1.29

1.4

1.2

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

2.84

1.29

1.8

2.3

7.18

5.69

pmol/l

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

2.36

1.29

9.3

9.2

1.13

1.19

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

509

1.44

1.28

3.4

3.1

0.00

0.01

estimate

0.50

131

(3013512) EKG study

260

1.52

1.28

2.3

2.8

—

(3041096) Erythrocytes [Presence] in Urine by Automated

406

1.45

1.26

3.3

2.7

0.00

0.01

estimate

0.50

125

(3019060) Gas panel - Arterial blood

2.46

1.26

3.0

3.7

—

(3014007) Fractional oxyhemoglobin in Arterial blood

2.23

1.23

9.2

8.8

97.01

94.09

—

(3048689) Calprotectin [Mass/mass] in Stool

221

1.52

1.17

2.5

2.7

99.38

78.85

ug/g

0.26

160

(3021601) Nitrite [Presence] in Urine by Test strip

653

1.41

1.16

3.8

3.4

0.00

estimate

-0.00

154

(3052851) Hemolysis interference index of Serum or Plasma

2.55

1.16

1.6

2.6

—

3.27

—

(3045414) Leukocytes [Presence] in Urine

104

1.72

1.16

2.3

1.8

0.00

estimate

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

137

1.63

1.14

2.2

2.4

24.58

25.42

0.12

132

(3021589) Normoblasts [#/volume] in Blood

558

1.39

1.11

9.4

8.7

0.00

e9/l

-0.00

456

(3001604) Monocytes [#/volume] in Blood

637

1.39

1.10

6.8

5.9

0.50

e9/l

0.10

571

(3035350) Ketones [Presence] in Urine by Test strip

657

1.39

1.10

3.8

3.4

0.00

estimate

-0.00

152

(3003458) Phosphate [Moles/volume] in Serum or Plasma

106

1.69

1.09

3.7

5.0

1.06

1.01

mmol/l

0.49

(3006315) Basophils [#/volume] in Blood

638

1.39

1.08

6.8

5.9

0.03

0.04

e9/l

0.54

571

(3009261) Glucose [Presence] in Urine by Test strip

658

1.39

1.08

3.8

3.4

0.00

estimate

-0.00

147

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

2.18

1.07

1.1

1.4

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

1.70

1.05

1.7

1.4

—

(3000492) Spirometry study

134

0.50

1.05

1.0

1.3

—

(4195642) Thrombophilia screening test

2.32

1.04

1.6

1.1

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.96

1.04

1.5

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

227

1.47

1.03

1.7

1.5

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.71

1.02

2.8

4.1

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

2.05

1.01

1.3

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

1.78

0.94

1.1

1.8

—

4.81

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

103

0.47

0.94

2.6

1.5

—

(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum

111

1.61

0.93

1.5

1.3

119.72

272.56

miu/ml

—

(3013115) Eosinophils [#/volume] in Blood

669

1.34

0.92

6.8

6.2

0.16

0.17

e9/l

0.76

604

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

199

1.44

0.87

1.7

2.0

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

290

1.38

0.85

2.5

2.0

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

115

1.55

0.81

1.6

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

107

1.56

0.80

1.5

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.79

0.0

1.1

—

(40760892) CBC W Ordered Manual Differential panel - Blood

350

1.33

0.78

4.4

4.2

—

(3010421) pH of Blood

2.22

0.77

4.0

2.2

7.40

7.42

—

(3034603) RHD gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal

2.12

0.75

1.8

1.5

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

110

1023

1.38

0.75

4.1

4.3

36.43

36.34

mmol/mol

0.06

104

994

(3044640) Blood type and Crossmatch panel - Blood

400

1.31

0.73

2.6

2.1

—

(3022096) Basophils/Leukocytes in Blood

584

1.29

0.73

7.1

5.8

0.60

0.68

0.62

551

(3006504) Eosinophils/Leukocytes in Blood

585

1.28

0.72

7.0

5.8

2.41

2.73

0.81

554

(3019069) Monocytes/Leukocytes in Blood

585

1.28

0.72

7.0

5.8

7.98

7.99

0.02

557

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.74

0.71

1.3

1.6

—

(3037551) Cancer Ag 125 [Units/volume] in Serum or Plasma

111

1.50

0.69

4.5

2.3

11.89

29.18

u/ml

3.08

105

(3011288) Drugs identified in Urine by Screen method Nominal

0.51

0.69

3.6

1.8

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

1.88

0.69

1.2

1.1

—

(3020891) Body temperature

1.88

0.69

2.8

4.9

36.82

36.99

°c

—

(3005033) Fetal Nuchal fold Thickness US

103

1.51

0.68

1.4

1.27

1.33

—

(3013707) Erythrocyte sedimentation rate [Velocity] in Red Blood Cells by Westergren method

902

1.30

0.68

4.9

3.9

9.07

8.01

mm/h

0.51

856

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

377

1.29

0.66

2.5

2.1

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

105

1.48

0.63

1.5

1.4

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

408

1.27

0.62

2.6

2.2

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

127

1220

1.56

0.62

12.4

11.2

14.98

17.95

mg/l

0.62

107

945

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

295

1.30

0.62

1.6

1.3

0.96

5.54

u/ml

1.36

131

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

458

1.26

0.60

2.2

1.8

—

(3015736) pH of Urine

546

1.25

0.59

2.8

3.1

6.27

6.20

0.19

316

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

401

1.26

0.59

1.3

1.58

1.39

u/ml

0.08

121

(3019198) Lymphocytes [#/volume] in Blood

666

1.24

0.58

7.0

5.8

1.91

1.94

e9/l

0.14

610

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

451

1.25

0.56

1.7

1.6

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

1.51

0.55

1.0

1.3

—

(3002030) Lymphocytes/Leukocytes in Blood

609

1.23

0.55

6.8

5.7

29.93

30.03

0.04

589

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

1.47

0.51

1.5

1.6

70.52

57.54

ug/l

0.20

(3023368) Bacteria identified in Blood by Culture

200

1.31

0.51

2.8

3.5

—

(3018418) pH of Serum or Plasma

275

1.26

0.50

2.9

3.7

7.39

7.40

0.85

189

(3003694) ABO and Rh group [Type] in Blood

467

1.22

0.49

2.2

1.8

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

115

1097

1.30

0.48

4.0

4.2

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

123

1186

1.36

0.45

6.0

5.7

1.60

1.68

mu/l

0.37

117

1147

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

238

0.77

0.45

1.4

1.9

2.70

3.24

ratio

2.20

182

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

105

1.37

0.43

1.4

1.7

—

(3050129) First trimester maternal screen panel - Serum or Plasma

150

1.31

0.43

1.4

1.5

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

1.58

0.42

1.4

1.2

—

(3018010) Neutrophils/Leukocytes in Blood

601

1.19

0.42

7.0

5.7

55.62

56.48

0.27

579

(3000850) Epithelial cells [#/volume] in Urine

225

1.25

0.41

2.0

2.4

5.95

13.50

e6/l

1.04

196

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.41

0.0

1.2

—

(3032080) INR in Blood by Coagulation assay

330

1.21

0.40

4.9

7.1

1.03

1.05

inr

0.18

271

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

311

1.21

0.40

1.6

1.4

10.60

28.71

iu/ml

—

(3018095) Leukocytes [#/volume] in Urine

433

0.83

0.39

4.3

3.2

12.53

38.95

e6/l

1.26

269

(3017732) Neutrophils [#/volume] in Blood

152

1.29

0.39

2.4

3.8

3.91

6.28

e9/l

0.58

139

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.39

0.0

2.9

—

(44806420) Estimation of glomerular filtration rate

0.00

0.39

0.0

1.7

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

448

1.18

0.38

1.8

1.9

94.25

96.42

pmol/l

0.11

249

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

135

1.30

0.37

1.9

1.5

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

1.45

0.36

2.0

1.8

—

(3023939) Sjogrens syndrome-A extractable nuclear Ab [Units/volume] in Serum

1.45

0.36

1.2

—

49.45

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

1.40

0.35

1.1

1.2

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

1.41

0.35

1.8

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

127

1.29

0.35

1.4

—

(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction

1.37

0.35

6.6

3.0

221.64

214.89

u/l

0.10

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

100

1.33

0.35

1.0

1.1

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

287

1.20

0.34

2.0

1.8

1.12

0.83

mg/l

0.17

218

(3007164) IgA [Mass/volume] in Serum or Plasma

356

1.17

0.32

1.4

1.3

2.23

2.03

g/l

0.20

238

(3007853) Bacteria identified in Skin by Aerobe culture

138

1.26

0.32

1.4

1.5

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

129

1.27

0.32

1.4

0.94

0.96

ratio

0.11

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

129

1.27

0.32

1.4

1.23

1.34

ratio

0.25

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

129

1.27

0.32

1.4

0.94

1.14

ratio

0.65

(3019150) Specific gravity of Urine by Refractometry

290

0.83

0.31

3.2

3.3

1.02

kg/l

0.08

183

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

1.29

0.30

1.3

1.4

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.32

0.29

8.0

5.8

106.64

105.40

mmol/l

0.51

(3026008) Bacteria identified in Urine by Culture

321

1.16

0.28

2.3

2.1

—

(40768804) Tissue Pathology biopsy report

556

1.14

0.28

2.2

1.9

—

(42870588) Differential panel, method unspecified - Blood

400

1.15

0.27

7.2

5.5

—

(3022145) Colonoscopy Study observation

126

1.21

0.22

1.3

1.4

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

279

1.14

0.22

2.0

1.9

—

(36304997) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells [Units/volume] in Blood

1.20

0.21

1.8

1.5

—

0.01

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

231

1.15

0.21

1.5

1.9

—

(3006442) Creatine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.6

—

67.64

—

(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.1

—

40.09

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.3

—

(3022575) Varicella zoster virus IgG Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

1859.18

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.0

—

(3044941) Cell count panel - Synovial fluid

0.00

0.21

0.0

1.3

—

(3011391) Calcitriol [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.0

—

114.27

—

(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum

0.00

0.21

0.0

1.2

—

(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3041806) Other cells [#/volume] in Blood by Manual count

0.00

0.21

0.0

2.0

—

0.50

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.21

0.0

2.4

—

105.10

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.21

0.0

2.4

—

3.90

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.21

0.0

1.0

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.21

0.0

2.4

—

1.18

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

15.2

—

932.17

—

(4035726) Immunohistochemistry procedure

1.27

0.21

1.2

1.3

—

(3016616) Dehydroepiandrosterone sulfate (DHEA-S) [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.2

—

8.41

—

(44813793) Dust mix specific IgE antibody measurement

0.00

0.21

0.0

1.2

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

19.8

—

1844.92

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.20

0.0

1.4

—

(3011951) Aspergillus fumigatus IgE Ab [Units/volume] in Serum

0.00

0.20

0.0

1.0

—

0.22

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

715

1.11

0.20

7.7

8.8

3.75

3.90

e9/l

0.34

631

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

927

1.12

0.20

3.3

3.0

34.74

29.07

u/l

0.42

898

(42868678) Cholesterol non HDL [Moles/volume] in Serum or Plasma

196

0.85

0.20

1.1

1.7

2.89

3.33

mmol/l

—

136

(40761536) Microorganisms panel - Urine sediment

118

1.21

0.20

3.1

2.8

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

113

1102

1.15

0.19

4.0

3.5

5.49

5.52

mmol/l

0.12

107

1043

(3003191) Choriogonadotropin [Presence] in Serum or Plasma

132

0.82

0.19

2.2

1.6

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

1.22

0.18

1.7

1.6

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

488

0.91

0.15

1.7

1.38

1.32

mmol/l

0.23

449

(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma

169

1.14

0.15

1.5

1.3

59.46

119.22

u/ml

—

(21494755) Public health laboratory ask at order entry panel

181

0.87

0.15

1.5

1.3

—

(4010399) Spirometry for bronchospasm with prolonged evaluation after bronchodilator

0.79

0.15

1.4

1.3

—

(40758558) Short blood count panel - Blood

323

0.91

0.13

3.9

6.3

—

(3023511) Choriogonadotropin [Units/volume] in Urine

1.19

0.13

1.2

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

152

1.14

0.13

2.5

2.3

7.60

322.73

ng/l

—

(3042936) Bacteria identified in Isolate by Culture

147

0.87

0.12

2.9

2.0

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.18

0.11

1.9

1.3

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

269

0.91

0.11

3.5

3.4

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.17

0.10

2.6

2.0

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.14

0.10

15.6

4.8

22.76

24.00

mmol/l

—

(40768793) Breast Pathology biopsy report

1.07

0.09

1.7

1.3

—

(3000991) Gas panel - Venous blood

1.04

0.08

12.2

6.0

—

(3002385) Erythrocyte [DistWidth] in Red Blood Cells

109

1106

0.93

0.08

13.0

13.4

13.32

13.31

0.04

109

1099

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

115

1165

0.92

0.08

4.0

3.9

2.83

2.84

mmol/l

0.04

110

1123

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

1.06

0.08

1.1

1.50

1.64

g/l

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

1.05

0.08

1.1

0.75

0.84

g/l

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

354

1.06

0.07

3.7

2.7

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

0.82

0.07

2.4

2.8

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.06

0.07

1.8

1.3

—

(1761868) Lipid panel - Serum or Plasma

585

0.96

0.06

2.2

2.4

—

(3001019) Free T4 and TSH panel - Serum or Plasma

139

1.09

0.05

1.9

1.6

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

300

1.04

0.03

2.1

1.5

—

(3000494) Fungus identified in Specimen by Culture

148

0.94

0.02

1.5

1.3

—

(3008898) HLA-B27 [Presence]

104

1.06

0.01

1.0

1.1

—

(36660697) Celiac disease serology panel - Serum

146

0.95

0.00

1.2

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

104

0.96

0.00

1.1

1.2

—

(40768797) Stomach Pathology biopsy report

159

1.01

0.00

1.3

1.2

—

(3005322) IgE [Units/volume] in Serum or Plasma

113

0.97

0.00

1.4

1.3

44.90

317.53

u/ml

0.70

101

(3021387) Prolactin [Units/volume] in Serum or Plasma

117

1.03

0.00

1.1

1.4

223.83

283.00

mu/l

0.93

101

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

116

1157

1.02

0.00

3.9

3.8

4.66

4.79

mmol/l

0.88

111

1119

(3020682) Albumin/Creatinine [Ratio] in Urine

212

0.99

0.00

3.7

3.9

28.31

9.45

mg/mmol

0.41

127

(3012516) Albumin [Mass/volume] in Urine

208

1.01

0.00

3.6

3.4

128.50

58.40

mg/l

0.37

130

(3002256) Pathology report gross observation

155

0.96

0.00

1.2

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

116

1155

1.03

0.00

3.9

3.7

1.49

1.53

mmol/l

0.65

111

1113

(1175426) CD3 cells/Lymphocytes in Blood

0.00

0.0

1.5

—

74.88

—

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

0.00

0.0

1.5

—

(40765089) Chromosome analysis panel - Blood by G-banded

0.00

0.0

1.0

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.89

0.00

1.2

1.1

—

0.50

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

-0.00

0.0

1.0

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

-0.00

0.0

1.6

—

(42528593) TIF1-gamma Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(3028717) Thiamine [Mass/volume] in Blood

0.00

-0.00

0.0

1.8

—

55.60

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

-0.00

0.0

1.0

—

32.43

—

(4211845) Urine protein measurement

0.00

-0.00

0.0

2.0

—

(43055514) Macroprolactin [Presence] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

(3025941) Bacteria identified in Stool by Culture

0.90

-0.00

1.1

1.2

—

(3007449) CD3+CD8+ (T8 suppressor) cells/cells in Blood

0.00

-0.00

0.0

1.0

—

26.00

—

(3001850) Coagulation factor XI activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

-0.00

0.0

1.0

—

(3013637) Mi-2 Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

3.2

—

1.68

—

(3006245) CD3-CD19+ cells/cells in Blood

0.00

-0.00

0.0

1.5

—

8.00

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3028334) Neisseria gonorrhoeae [Presence] in Specimen by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3028009) Chlamydia trachomatis IgG Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

6.36

—

(42529582) MDA5 Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

-0.00

0.0

1.0

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3027831) CD3-CD16+CD56+ (Natural killer) cells/cells in Blood

0.00

-0.00

0.0

1.6

—

12.71

—

(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.6

—

344.00

—

(40760543) Extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.0

—

(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.6

—

(44817194) Complement alternate pathway AH50 actual/normal in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

88.80

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

-0.00

0.0

1.1

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

108

1080

1.00

-0.00

3.4

3.2

1.12

1.15

mmol/l

0.24

102

1030

(3002348) Coagulation factor XII activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

-0.00

0.0

1.0

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

100

1.00

-0.00

1.1

1.5

—

(3037826) lamoTRIgine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.0

—

15.80

—

(3045209) Lutropin/Follitropin [Ratio] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

(3051651) Icteric interference index of Serum or Plasma

0.00

-0.00

0.0

4.6

—

0.80

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3035320) C reactive protein [Mass/volume] in Body fluid

0.00

-0.00

0.0

1.9

—

23.29

—

(3016845) Adenovirus Ag [Presence] in Specimen by Immunofluorescence

0.00

-0.00

0.0

1.0

—

(42529598) SUMO-activating enzyme subunit 1 Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(3032700) Glomerular basement membrane Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.3

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

-0.00

0.0

1.2

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture

0.00

-0.00

0.0

2.3

—

(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

0.00

-0.00

0.0

1.0

—

2204.40

—

(3011897) Casein IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

0.02

—

(36304052) Adalimumab Ab [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

3.0

—

(3034426) Prothrombin time (PT)

0.00

-0.00

0.0

1.2

—

27.80

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3001684) Respiratory syncytial virus Ag [Presence] in Specimen

0.00

-0.00

0.0

1.0

—

(44816893) Food Allergen Mix 50 (Kiwi+Pineapple+Banana+Mango) IgE Ab [Units/volume] in Serum by Multidisk

0.00

-0.00

0.0

1.0

—

0.57

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(40768795) Lymph node Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(4198724) Urine methamphetamine measurement

0.00

-0.00

0.0

1.2

—

(3049714) Procollagen type I.N-terminal propeptide [Mass/volume] in Serum

0.00

-0.00

0.0

1.7

—

39.67

—

(3003434) Protein [Mass/volume] in Pleural fluid

0.00

-0.00

0.0

1.2

—

46.90

—

(1002224) Polysomnography panel

0.89

-0.00

1.0

—

(3005791) Eosinophil cationic protein (ECP) [Mass/volume] in Serum

0.00

-0.00

0.0

6.2

—

21.70

—

(3006462) Nitrate [Presence] in Urine

0.00

-0.00

0.0

2.0

—

(3037534) Parathyrin related protein [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

68.80

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

-0.00

0.0

1.8

—

8.66

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

0.97

-0.00

1.5

2.0

—

Mortality – FinRegistry

↥

Association

Association between endpoint O15_PUERP_ANEST_COMPL and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_PUERP_ANEST_COMPL.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: O15_PUERP_ANEST_COMPL – Complications of anaesthesia during the puerperium

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Complications of anaesthesia during the puerperium

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints