No definition available.
Other congenital malformations of upper alimentary tract
Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
285 |
4. Check minimum number of eventsNone |
285 |
5. Include endpointsNone |
285 |
6. Filter based on genotype QC (FinnGen only) |
256 |
Control definitions (FinnGen only)
- Control exclude
- Q17_OTHER_CONGEN_MALFO_DIGES_SYSTEM1
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- Q3[8-9]|Q4[0-5]
- Name in latin
- Aliae malformationes congenitae tractus digestorii superioris
Similar endpoints
↥List of similar endpoints to
Other congenital malformations of upper alimentary tract
based on the number of shared cases.
Similar with more cases:
- Other congenital malformations of the digestive system
- Other congenital malformations of the digestive system, including avohilmo
- Congenital malformations, deformations and chromosomal abnormalities
- Congenital malformations, deformations and chromosomal abnormalities, including avohilmo
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2520 | 841 | 1677 |
| Only index persons | 1862 | 650 | 1212 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.02 | 0.05 |
| Only index persons | 0.04 | 0.02 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 5.28 | 15.36 | 0.17 |
| Only index persons | 15.21 | 41.69 | 1.01 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 256 | 116 | 140 |
| Unadjusted period prevalence (%) | 0.05 | 0.04 | 0.06 |
| Median age at first event (years) | 62.02 | 58.70 | 64.78 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 264
- Matched controls
- 2640
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q40.9
ICD-10 Finland
Congenital malformation of upper alimentary tract, unspecified
+∞
254.0
201
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
18.6
109.5
215
504
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
6.7
36.9
70
135
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
7.2
36.7
64
113
Q40.1
ICD-10 Finland
Congenital hiatus hernia
+∞
30.8
29
*
SPAT1301
SPAT
No procedures
4.2
29.2
136
537
SPAT1101
SPAT
Orthostatic test
8.7
27.9
38
50
UJF32
NOMESCO Finland
Coloscopy
4.1
27.7
118
435
SPAT1249
SPAT
Treatment-related counselling outside office
3.7
24.6
153
713
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
4.5
23.4
70
196
JCA55
NOMESCO Finland
Endoscopic dilatation of oesophagus
36.0
22.9
29
9
Q40.0
ICD-10 Finland
Congenital hypertrophic pyloric stenosis
+∞
22.2
21
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
9.1
19.6
25
30
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
4.8
18.6
47
114
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
6.9
18.4
30
48
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
4.2
18.3
56
158
SPAT1210
SPAT
Application of cast or individual aid
7.3
18.2
28
42
A02BC03
ATC
lansoprazole; oral
3.1
17.6
109
485
-, ,
ICD-10 Finland
19.6
16.8
25
14
K29.7
ICD-10 Finland
Gastritis, unspecified
7.1
16.5
26
40
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
3.3
15.9
78
300
Z09.8
ICD-10 Finland
Follow-up examination after other treatment for other conditions
7.5
15.5
23
33
SPAT1312
SPAT
General health counselling
2.8
14.8
120
607
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
14.5
14.5
24
18
SPAT1153
SPAT
Removal of sutures
2.8
14.4
114
567
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
10.9
13.3
25
25
SPAT1285
SPAT
Provision of consultation response
5.7
13.3
26
50
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.7
12.4
44
136
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.1
11.9
60
231
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
11.3
11.5
21
20
SAB01
NOMESCO Finland
Restricted oral and dental health check by dental hygienist or dental assistant
3.1
10.8
50
183
SPAT1260
SPAT
Consultation of another employee
2.8
10.7
67
290
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
4.0
10.6
32
88
G40.4
ICD-10 Finland
Other generalized epilepsy and epileptic syndromes
114.4
10.5
11
*
JDH60
NOMESCO Finland
Pyloromyotomy
+∞
10.5
10
*
G40.9
ICD-10 Finland
Epilepsy, unspecified
5.2
10.5
22
45
SPAT1256
SPAT
Intramuscular and subcutaneous injection
2.3
10.4
133
798
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.4
10.3
99
525
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.5
10.2
37
116
R13
ICD-10 Finland
Dysphagia
3.7
10.0
34
102
SPAT1104
SPAT
Monitoring of emergency patient
4.2
9.9
27
69
SPAT1263
SPAT
Sampling
2.3
9.8
129
778
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
8.9
9.8
20
24
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
4.1
9.6
28
75
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.2
9.1
151
992
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.9
9.1
28
78
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.9
9.0
49
195
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
5.0
9.0
20
43
SPAT1310
SPAT
Counselling related to known health issue
2.3
9.0
103
583
A02BC04
ATC
rabeprazole; oral
3.3
8.5
34
113
N03AG01
ATC
valproic acid; systemic, rectal
3.7
8.5
28
82
T18.1
ICD-10 Finland
Foreign body in oesophagus
13.4
8.5
14
11
Z98.0
ICD-10 Finland
Intestinal bypass and anastomosis status
+∞
8.4
8
*
WX320
NOMESCO Finland
Spinalanesthesy
0.2
8.4
9
400
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.2
8.3
91
502
SPAT1229
SPAT
Assessment of need for aid
3.6
8.0
27
80
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.7
8.0
49
207
SPAT1053
SPAT
Memory test
2.6
8.0
53
234
Z71.8
ICD-10 Finland
Other specified counselling
0.3
8.0
25
671
M01AC06
ATC
meloxicam; systemic, rectal
2.1
7.9
105
623
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.1
7.9
107
641
A02BC02
ATC
pantoprazole; systemic
2.2
7.9
187
1382
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.8
7.8
41
160
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.0
7.7
22
58
Q40.8
ICD-10 Finland
Other specified congenital malformations of upper alimentary tract
+∞
7.3
7
*
181
Kela drug reimbursment
Retigabine and vigabatrin
+∞
7.3
7
*
K25.3
ICD-10 Finland
Gastric ulcer, Acute without haemorrhage or perforation
20.7
7.2
10
5
K25.7
ICD-10 Finland
Gastric ulcer, Chronic without haemorrhage or perforation
10.4
7.1
13
13
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.7
7.0
40
163
L04AX01
ATC
azathioprine; systemic
4.3
6.9
18
44
N03AF02
ATC
oxcarbazepine; oral
4.3
6.9
18
44
R03AC03
ATC
terbutaline; inhalant
2.6
6.9
44
190
183
Kela drug reimbursment
Lamotrigin and topiramate
9.7
6.9
13
14
SPAT1203
SPAT
Injection therapy, other than intramuscular or subcutaneous
4.5
6.9
17
40
SPAT1255
SPAT
Intravenous administration of medicine
3.2
6.5
26
86
SPAT1324
SPAT
Screening procedure
2.5
6.5
43
188
R63.8
ICD-10 Finland
Other symptoms and signs concerning food and fluid intake
71.5
6.5
7
*
TKE00
NOMESCO Finland
Needle biopsy of prostate
3.8
6.4
20
56
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.3
6.4
57
285
A02BC05
ATC
esomeprazole; systemic
1.9
6.3
112
725
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.5
6.3
43
191
K28.9
ICD-10 Finland
Gastrojejunal ulcer, unspecified as acute or chronic, without haemorrhage or perforation
+∞
6.3
6
*
K23.8*B37.8
ICD-10 Finland
Esophagitis caused by candidiasis
27.4
6.3
8
*
WX100
NOMESCO Finland
Conjunctival surface anesthesia
0.1
6.3
*
208
A03FA02
ATC
cisapride; oral, rectal
3.1
6.1
27
95
N06AX11
ATC
mirtazapine; oral
2.0
6.1
96
595
GD1BA
NOMESCO Finland
Extensive X-ray examination of thorax
12.9
6.1
10
8
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
5.4
6.1
17
33
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
8.9
6.1
12
14
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
8.9
6.1
12
14
Z98.8
ICD-10 Finland
Other specified postsurgical states
10.4
6.1
11
11
SFA00
NOMESCO Finland
Small restoration
2.4
6.0
44
202
H03AA01
ATC
levothyroxine sodium; systemic
2.1
6.0
63
337
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
170
247
17.52
128.89
14.3
8.1
—
—
—
0
0
181
528
8.72
67.37
8.0
4.1
1.02
1.02
kg/l
0.66
117
357
100
209
7.09
49.80
3.8
2.4
2.89
7.06
ug/l
2.65
93
187
172
695
5.23
38.33
8.1
4.0
0.00
0.03
estimate
—
9
240
84
187
6.12
38.27
3.0
3.2
63.17
65.06
ml/min/173m2
0.15
36
83
189
929
4.64
30.00
7.4
3.9
1.59
0.01
estimate
0.52
17
218
62
142
5.40
26.70
3.8
6.9
0.65
0.63
%
0.27
62
142
62
143
5.36
26.47
3.8
7.0
1.16
1.26
%
0.35
62
143
31
48
7.18
19.66
1.7
1.4
—
—
—
0
0
202
1233
3.72
19.34
7.8
4.0
0.06
0.00
estimate
0.48
17
257
202
1245
3.65
18.77
8.0
4.0
0.00
6.15
estimate
0.50
17
264
202
1262
3.56
17.99
8.0
4.0
0.18
1.25
estimate
0.41
17
243
106
459
3.19
17.97
3.6
2.9
2.44
2.45
mmol/l
0.47
98
411
142
736
3.01
17.36
2.9
2.2
132.09
213.68
u/l
1.90
131
703
73
282
3.20
14.65
6.1
10.3
1.60
0.79
mmol/l
1.22
54
245
76
308
3.06
13.99
7.5
5.6
1.63
1.63
mmol/l
0.00
64
250
153
903
2.65
13.47
6.4
4.0
22.89
36.56
ng/l
1.86
121
665
138
793
2.55
12.58
3.9
3.5
2.37
2.36
mmol/l
0.41
132
712
118
634
2.56
12.35
3.2
2.3
3.67
2.81
mg/l
3.58
107
557
130
740
2.49
11.91
3.7
2.8
84.82
67.82
u/l
0.22
124
686
162
1047
2.42
10.85
8.3
5.5
35.76
35.65
g/l
0.10
156
988
52
199
3.01
10.35
3.0
2.6
0.20
0.24
e6/l
0.14
52
194
194
1399
2.46
9.57
11.1
11.0
4.23
4.07
e9/l
0.41
184
1199
29
82
3.85
9.24
1.6
1.2
—
—
—
0
0
28
80
3.80
8.79
1.6
1.2
—
—
—
0
0
36
126
3.15
8.29
1.6
1.4
—
—
—
0
0
35
121
3.18
8.22
1.6
1.4
—
—
—
0
0
221
1774
2.51
7.29
10.0
8.6
88.38
86.23
u/l
0.19
215
1666
51
234
2.46
7.02
6.7
11.3
1.61
1.34
mmol/l
0.87
51
229
46
202
2.55
6.94
1.5
1.4
—
—
—
0
0
20
55
3.85
6.61
1.8
2.5
12.43
104.50
ug/min
—
6
30
119
814
1.84
5.49
4.5
3.4
7.37
7.81
mmol/l
0.55
114
697
151
1118
1.82
5.32
13.0
8.3
1.18
1.21
mmol/l
5.41
144
1036
164
1247
1.83
5.27
7.2
7.6
12.86
13.66
umol/l
0.18
157
1193
24
93
2.74
4.62
3.2
1.9
1.50
4.16
ug/l
0.43
24
85
17
54
3.30
4.57
1.5
1.5
—
—
—
0
0
204
1695
1.90
4.55
5.9
4.6
10.76
11.71
mm/h
0.67
195
1570
19
459
0.37
4.52
3.7
4.0
78.00
285.67
ng/l
1.28
12
365
248
2223
2.91
4.47
22.7
16.9
25.33
23.77
mg/l
0.30
210
1826
42
215
2.13
4.43
5.5
6.5
24.47
23.86
mmol/l
0.79
42
215
73
454
1.84
4.42
2.6
3.3
1.83
0.87
e6/l
0.89
64
241
250
2256
3.04
4.33
29.2
20.4
4.00
3.99
mmol/l
0.32
245
2209
54
307
1.95
4.28
2.0
2.1
—
—
—
0
0
87
577
1.76
4.23
4.0
3.3
318.32
343.56
umol/l
1.43
72
509
108
764
1.70
4.15
4.7
3.5
920.53
1212.31
ng/l
0.63
99
647
81
532
1.75
4.05
2.0
1.7
1.62
1.62
mg/l
0.00
56
410
64
392
1.84
4.04
1.7
1.7
1944.62
1216.83
nmol/l
9.97
53
306
39
681
0.50
3.98
4.9
3.4
0.00
0.12
estimate
—
10
210
0
99
0.00
3.94
0.0
2.5
—
2.98
—
0
94
12
28
4.44
3.87
1.2
1.2
—
—
—
0
0
134
1019
1.64
3.81
2.0
2.1
97.07
95.04
pmol/l
0.26
91
531
0
89
0.00
3.57
0.0
2.7
—
0.55
—
0
82
236
2110
2.12
3.57
6.9
5.2
4.34
4.53
mmol/l
1.99
227
1961
12
31
4.00
3.54
1.7
1.7
—
—
—
0
0
96
684
1.63
3.47
6.7
4.8
22.87
21.64
%
0.39
61
350
83
571
1.66
3.43
2.4
2.6
—
—
—
0
0
15
53
2.94
3.42
2.1
1.6
—
—
—
0
0
227
2010
1.92
3.42
6.1
4.4
1.32
1.26
mmol/l
0.91
216
1845
8
235
0.32
3.39
11.0
3.4
—
—
—
0
0
11
28
4.05
3.33
1.8
1.7
—
—
—
0
0
11
28
4.05
3.33
1.8
1.7
—
—
—
0
0
11
28
4.05
3.33
1.8
1.7
—
—
—
0
0
13
43
3.13
3.30
2.2
1.6
—
—
—
0
0
12
34
3.65
3.24
1.7
1.7
—
—
—
0
0
136
1066
1.57
3.23
2.9
2.9
—
—
estimate
—
0
0
7
11
6.50
3.20
2.0
1.6
98.31
55.03
ng/l
—
7
11
21
425
0.45
3.19
7.2
3.4
3.43
1.58
e6/l
0.39
13
216
14
50
2.90
3.14
1.6
1.6
—
—
—
0
0
68
456
1.66
3.07
1.5
1.6
—
—
—
0
0
6
8
7.64
3.07
3.7
1.0
7.42
10.56
ug/l
—
6
8
15
57
2.73
3.02
1.1
1.3
—
—
—
0
0
0
80
0.00
2.98
0.0
2.8
—
0.00
—
0
72
51
320
1.74
2.93
1.7
2.0
—
—
—
0
0
9
22
4.20
2.91
5.0
3.5
706.22
740.55
mg
—
9
22
6
9
6.79
2.88
1.2
1.0
—
—
—
0
0
227
2038
1.81
2.87
7.2
5.1
1.96
1.98
mu/l
0.09
222
1857
11
33
3.43
2.84
1.5
1.5
—
—
—
0
0
8
18
4.55
2.81
1.5
4.2
1.25
1.17
%
—
8
18
16
66
2.52
2.77
2.0
1.6
—
—
—
0
0
5
6
8.46
2.76
9.0
5.7
—
—
—
0
0
232
2104
1.85
2.73
6.4
5.1
1.42
1.45
mmol/l
0.54
222
1944
42
254
1.78
2.73
2.5
2.8
0.21
0.21
g/l
0.06
42
239
235
2144
1.87
2.65
7.7
5.9
2.52
2.64
mmol/l
1.13
228
1992
14
56
2.58
2.57
1.6
1.6
—
—
—
0
0
150
1240
1.49
2.55
14.5
8.4
1.19
1.21
mmol/l
2.91
142
1084
225
2034
1.72
2.53
10.1
6.6
40.67
39.75
mmol/mol
0.72
218
1915
18
85
2.20
2.35
1.3
1.2
—
—
—
0
0
19
92
2.15
2.33
2.5
3.1
—
—
—
0
0
43
275
1.67
2.30
1.6
1.5
—
—
—
0
0
228
2084
1.69
2.26
7.6
5.2
6.08
5.97
mmol/l
0.73
222
1911
99
769
1.46
2.24
4.3
4.1
153.82
9.83
mg/mmol
0.49
77
500
17
82
2.15
2.12
2.0
1.6
—
—
—
0
0
29
170
1.79
2.11
1.2
1.3
89.25
436.61
u/ml
1.35
24
157
94
733
1.44
2.06
4.0
3.5
0.45
0.48
e6/l
0.05
85
540
14
63
2.29
2.05
2.9
1.4
222.56
256.69
u/ml
—
9
26
59
423
1.51
1.96
2.2
2.0
—
—
—
0
0
12
53
2.32
1.83
1.1
1.5
—
—
—
0
0
13
60
2.23
1.81
3.8
1.6
—
—
—
0
0
35
514
0.63
1.76
1.9
3.4
0.69
0.81
ug/l
0.20
30
349
11
48
2.35
1.73
1.1
1.4
—
—
—
0
0
0
39
0.00
1.35
0.0
1.3
—
—
—
0
0
61
473
1.38
1.33
1.3
1.8
515.54
29695882.38
pmol/l
0.50
48
394
76
611
1.34
1.32
1.5
1.4
2.24
2.00
u/ml
0.06
30
161
35
248
1.47
1.25
3.1
2.2
346.41
375.59
nmol/l
0.30
29
237
18
109
1.70
1.22
2.1
2.1
—
—
—
0
0
18
109
1.70
1.22
2.6
2.8
20.44
66.10
u/ml
1.17
18
103
14
79
1.82
1.19
2.2
1.6
—
—
—
0
0
0
36
0.00
1.15
0.0
1.7
—
—
—
0
0
5
21
2.41
1.09
2.0
1.2
—
—
—
0
0
5
21
2.41
1.09
2.0
1.2
—
—
—
0
0
11
59
1.90
1.09
8.1
3.0
40.64
36.37
umol/l
0.28
11
54
7
33
2.15
1.06
1.3
1.5
—
—
—
0
0
14
84
1.70
1.00
1.5
1.6
—
0.02
—
0
18
5
23
2.20
0.98
1.2
1.4
—
—
—
0
0
0
29
0.00
0.98
0.0
3.3
—
18.33
—
0
16
0
32
0.00
0.95
0.0
3.8
—
—
—
0
0
12
72
1.70
0.86
2.2
1.3
—
—
—
0
0
24
173
1.43
0.82
1.8
1.5
—
—
—
0
0
0
24
0.00
0.79
0.0
1.3
—
—
—
0
0
0
24
0.00
0.79
0.0
1.5
—
—
—
0
0
0
24
0.00
0.79
0.0
1.3
—
—
—
0
0
0
24
0.00
0.79
0.0
1.3
—
—
—
0
0
8
48
1.69
0.79
3.1
1.2
3.93
3.88
mmol/l
—
8
42
97
853
1.22
0.79
5.7
5.9
2.44
2.67
ug/l
0.15
89
763
0
26
0.00
0.79
0.0
1.2
—
94.40
—
0
5
49
400
1.28
0.77
1.3
1.3
153.35
30.39
iu/ml
—
8
127
0
28
0.00
0.76
0.0
1.1
—
—
—
0
0
0
28
0.00
0.76
0.0
1.2
—
—
—
0
0
9
53
1.72
0.76
3.1
1.3
14.11
198.05
e6/l
—
9
37
5
24
2.10
0.75
1.2
1.8
—
—
—
0
0
9
59
1.54
0.69
2.8
1.7
189.00
223.26
pmol/l
—
9
53
214
2045
1.25
0.69
11.5
16.5
79.11
80.33
ml/min/173m2
0.33
206
1891
13
87
1.52
0.64
1.5
2.2
—
—
—
0
0
14
96
1.48
0.63
2.1
1.9
285.58
336.36
ug/l
0.20
14
91
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
1.3
—
—
—
0
0
0
22
0.00
0.59
0.0
2.3
—
—
—
0
0
0
22
0.00
0.59
0.0
1.6
—
—
—
0
0
0
22
0.00
0.59
0.0
2.3
—
—
—
0
0
0
23
0.00
0.58
0.0
1.0
—
515.93
—
0
14
0
23
0.00
0.58
0.0
1.1
—
35.95
—
0
13
18
139
1.32
0.45
1.2
1.3
—
56.86
—
0
11
5
32
1.57
0.42
1.0
1.2
—
—
—
0
0
5
33
1.52
0.41
1.4
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
192.29
—
0
15
0
15
0.00
0.41
0.0
1.2
—
160.87
—
0
15
0
16
0.00
0.41
0.0
1.2
—
12.44
—
0
16
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
12.24
—
0
12
16
125
1.30
0.38
1.3
1.2
93.08
132.18
u/ml
—
9
41
12
91
1.33
0.34
2.8
1.4
—
—
—
0
0
25
211
1.20
0.33
1.5
2.0
—
—
—
0
0
10
76
1.33
0.28
1.6
2.0
—
—
—
0
0
11
139
0.78
0.27
1.3
1.0
—
—
—
0
0
10
78
1.29
0.24
1.5
1.1
—
7.39
—
0
8
41
373
1.12
0.22
1.3
1.3
13.48
10.84
u/ml
0.08
24
132
5
40
1.25
0.22
5.4
2.6
20.06
18.40
ug/l
—
5
40
0
11
0.00
0.21
0.0
1.1
—
0.97
—
0
6
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
8.80
—
0
10
0
13
0.00
0.21
0.0
3.2
—
4.68
—
0
13
0
13
0.00
0.21
0.0
3.2
—
10.41
—
0
13
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.7
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
2.77
—
0
9
5
67
0.74
0.17
1.2
1.3
—
—
—
0
0
9
79
1.14
0.15
2.6
1.8
43.89
41.15
nmol/l
—
9
73
12
103
1.17
0.14
37.7
9.9
1.37
1.40
mg/l
0.08
12
92
25
229
1.10
0.13
1.6
2.2
—
—
—
0
0
14
157
0.89
0.11
14.7
5.9
24.58
24.64
mmol/l
0.03
14
152
42
407
1.04
0.04
4.5
2.6
2.40
2.31
g/l
0.40
42
376
39
379
1.03
0.03
4.4
2.6
21.62
22.62
%
0.19
39
355
139
1401
0.98
0.02
2.7
3.2
—
—
—
0
0
146
1466
0.99
0.00
3.4
3.6
65.86
49.09
u/l
1.01
135
1380
0
8
0.00
0.00
0.0
1.5
—
1.21
—
0
8
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
42.97
—
0
7
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
70
1.00
-0.00
1.0
1.2
1.33
1.58
g/l
—
7
70
0
9
0.00
-0.00
0.0
1.0
—
92.67
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
0.04
—
0
5
7
74
0.94
-0.00
1.1
1.2
0.81
0.90
g/l
—
7
74
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.8
—
—
—
0
0
5
51
0.98
-0.00
1.0
1.3
—
46.62
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
31.00
—
0
6
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
79
0.88
-0.00
1.1
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
7.8
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT | 1.843 [1.4, 2.43] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.266 |
During the follow-up period (1.1.1998 — 31.12.2019), 112 out of 751 females with Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT | 2.23 [1.68, 2.95] | < 0.001 |
| Birth year | 0.985 [0.97, 1.0] | 0.007 |
During the follow-up period (1.1.1998 — 31.12.2019), 167 out of 1492 males with Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT died.
Mortality risk
Mortality risk for people of age
years, who have Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.224% | 0.399% |
| 5 | 1.109% | 2.275% |
| 10 | 2.602% | 5.744% |
| 15 | 5.149% | 10.659% |
| 20 | 8.668% | 17.596% |
Relationships between endpoints
↥Index endpoint: Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT – Other congenital malformations of upper alimentary tract
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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