Other and unspecified nail disorders

L12_NAILNAS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L60.8, L60.9
  • Hospital discharge: ICD-9 7038E|7038G|7038X|7039
  • Hospital discharge: ICD-8 70301|7030[8-9]
  • Cause of death: ICD-10 L60.8, L60.9
  • Cause of death: ICD-9 7038E|7038G|7038X|7039
  • Cause of death: ICD-8 70301|7030[8-9]

2 out of 7 registries used, show all original rules.

1000

4. Check minimum number of events

None

1000

5. Include endpoints

None

1000

6. Filter based on genotype QC (FinnGen only)

910

Control definitions (FinnGen only)

Control exclude
L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4733 2702 2009
Only index persons 4307 2489 1818
Unadjusted period prevalence (%)
Whole population 0.07 0.08 0.06
Only index persons 0.08 0.09 0.07
Median age at first event (years)
Whole population 51.51 52.58 50.15
Only index persons 52.27 53.11 51.12

-FinnGen-

Key figures

All Female Male
Number of individuals 910 601 309
Unadjusted period prevalence (%) 0.19 0.21 0.14
Median age at first event (years) 59.18 58.05 61.39

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
943
Matched controls
9430
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L60.9
ICD-10 Finland
Nail disorder, unspecified
326.3
307.7
627
57
L60.8
ICD-10 Finland
Other nail disorders
145.8
307.7
344
37
RJ411, ,
NOMESCO Finland
37.9
91.5
57
16
S22
ICPC
Nail symptom/complaint
4.9
63.5
158
373
L60.0
ICD-10 Finland
Ingrowing nail
6.3
62.8
113
199
B35.1
ICD-10 Finland
Tinea unguium
4.6
54.6
144
355
RJ410, ,
NOMESCO Finland
72.3
53.8
61
9
RJ421, ,
NOMESCO Finland
89.9
53.6
59
7
XQ848
NOMESCO Finland
Dermatological photography
7.9
51.9
74
101
RJ190, ,
NOMESCO Finland
143.0
51.4
54
*
L03.0
ICD-10 Finland
Cellulitis of finger and toe
3.9
46.8
158
466
TQW80
NOMESCO Finland
Local dermatologic skincare
8.1
46.4
64
84
QDH00
NOMESCO Finland
Avulsion of toe nail
68.7
45.6
52
8
RJ422, ,
NOMESCO Finland
236.0
44.3
45
*
D01AE16
ATC
amorolfine; topical
3.4
41.6
178
611
L60.1
ICD-10 Finland
Onycholysis
12.2
40.5
41
35
D01BA02
ATC
terbinafine; oral
2.6
40.2
321
1546
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.6
37.8
137
421
E0000UV, ,
ATC
2.4
36.2
482
2898
L84
ICD-10 Finland
Corns and callosities
5.3
34.1
72
146
XQ845
NOMESCO Finland
Dermatoscopy
7.7
31.6
45
61
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
3.5
25.6
93
284
Z3229
NOMESCO Finland
Other healthcare associate professional
3.1
24.9
111
385
QDH01
NOMESCO Finland
Excision of nail bed in toe
92.6
24.8
27
*
RJ511, ,
NOMESCO Finland
57.6
24.1
28
5
127
Kela drug reimbursment
Transplant complication
7.9
23.9
33
43
D07AD01
ATC
clobetasol; topical
2.4
23.9
201
963
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.2
23.6
247
1298
L04AA06
ATC
mycophenolic acid; systemic
6.4
23.3
39
63
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
6.6
21.5
35
55
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
5.4
21.2
42
80
D07AC01
ATC
betamethasone; topical
2.0
21.0
379
2416
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
4.2
20.2
55
137
R23.8
ICD-10 Finland
Other and unspecified skin changes
2.1
20.0
246
1365
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.1
19.3
240
1336
SPAT1260
SPAT
Consultation of another employee
2.2
18.8
190
976
J01DB01
ATC
cefalexin; oral
2.3
18.5
811
6835
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
5.7
18.3
34
61
A46
ICD-10 Finland
Erysipelas
2.3
18.0
156
750
L60.3
ICD-10 Finland
Nail dystrophy
23.3
17.8
25
11
TNX92
NOMESCO Finland
Supporting bandage or orthosis of lower limb
5.7
17.5
33
60
L04AD01
ATC
ciclosporin; systemic
6.0
17.1
30
51
L04AX03
ATC
methotrexate; systemic
2.5
16.9
118
515
L17
ICPC
Foot/toe symptom/complaint
1.8
16.9
331
2134
SPAT1153
SPAT
Removal of sutures
1.9
16.7
311
1972
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.4
16.5
60
183
RJ420, ,
NOMESCO Finland
18.3
16.5
25
14
J01FF01
ATC
clindamycin; systemic
1.9
16.0
272
1670
ZXC50
NOMESCO Finland
Cryotherapy
4.3
15.9
41
98
J02AC02
ATC
itraconazole; systemic
2.0
15.7
187
1016
B35.3
ICD-10 Finland
Tinea pedis
3.2
15.3
61
197
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
4.1
15.2
42
106
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
14.7
236
1417
J01MA02
ATC
ciprofloxacin; systemic
1.8
14.7
361
2466
A10AB05
ATC
insulin aspart; parenteral
2.6
14.7
91
375
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.2
14.6
132
644
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
2.8
14.5
77
293
J02AC01
ATC
fluconazole; systemic
1.7
14.5
396
2784
L57.0
ICD-10 Finland
Actinic keratosis
2.3
14.2
113
522
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.7
14.1
79
309
SPAT1263
SPAT
Sampling
1.7
14.1
401
2844
A11CC03
ATC
alfacalcidol; systemic
4.8
14.1
32
69
L40.0
ICD-10 Finland
Psoriasis vulgaris
3.3
14.0
53
166
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
12.9
13.9
24
19
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.1
13.8
59
199
Z94.0
ICD-10 Finland
Kidney transplant status
10.7
13.8
26
25
V03AE01
ATC
polystyrene sulfonate; oral
11.1
13.6
25
23
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.9
13.5
193
1113
RJ414, ,
NOMESCO Finland
26.2
13.4
18
7
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
13.2
359
2505
RJ210, ,
NOMESCO Finland
40.7
13.2
16
*
S94
ICPC
Ingrowing nail
4.5
13.2
32
73
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.9
13.1
191
1108
A02BC02
ATC
pantoprazole; systemic
1.7
13.1
645
5255
N03AX16
ATC
[U] pregabalin
1.8
13.0
226
1386
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.8
13.0
261
1672
TQW99
NOMESCO Finland
Other minor procedure on skin
3.0
13.0
60
212
H02AB06
ATC
prednisolone; systemic
1.7
12.8
448
3330
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
12.8
324
2214
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
12.7
444
3296
A10AB01
ATC
insulin (human); parenteral
3.3
12.6
48
151
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.1
12.6
131
674
L40.8
ICD-10 Finland
Other psoriasis
13.4
12.5
21
16
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
2.2
12.4
119
593
S18
ICPC
Laceration/cut
1.6
12.2
453
3403
UJF32
NOMESCO Finland
Coloscopy
1.8
12.2
245
1564
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.3
12.2
94
428
TK800
NOMESCO Finland
Hemodialysis
4.7
12.2
28
61
NHQ40
NOMESCO Finland
Amputation of toe
5.6
12.2
23
42
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
18.3
12.1
18
10
L60
ICD-10 Finland
Nail disorders
10.2
12.0
23
23
SPAT1301
SPAT
No procedures
1.7
11.8
291
1967
S29
ICPC
Skin symptom/complaint other
1.8
11.7
208
1280
N18.8
ICD-10 Finland
Other chronic renal failure
4.8
11.7
26
55
RD211, ,
NOMESCO Finland
3.0
11.6
53
186
D01AE15
ATC
terbinafine; topical
2.5
11.6
76
322
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
4.4
11.5
29
68
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.1
11.5
114
575
C03CA01
ATC
furosemide; systemic
1.7
11.5
244
1580
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.0
11.5
137
741
J01FA10
ATC
azithromycin; systemic
1.6
11.3
555
4435
S09
ICPC
Infected finger/toe
3.2
11.2
44
141
SPAT1310
SPAT
Counselling related to known health issue
1.7
11.2
300
2067
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
11.1
237
1536
A10AE05
ATC
insulin detemir; parenteral
2.6
11.1
65
261
Z00.0
ICD-10 Finland
General medical examination
1.8
11.0
197
1213
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.4
10.8
76
332
A12AA04
ATC
calcium carbonate; oral
5.2
10.8
22
43
E000001, ,
ATC
1.8
10.7
188
1149
A10AA02, ,
ATC
3.3
10.6
40
125
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.3
10.6
85
393
D07AB02
ATC
hydrocortisone butyrate; topical
1.6
10.5
287
1981
L04AD02
ATC
tacrolimus; systemic
7.6
10.2
23
31
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
10.1
266
1815
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.9
10.0
135
760
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
9.9
173
1054
SPAT1262
SPAT
Handing over of treatment supplies
1.8
9.9
157
929
Z49.1
ICD-10 Finland
Extracorporeal dialysis
7.7
9.9
22
29
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.1
9.9
97
487
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
3.6
9.8
32
91
L04AX01
ATC
azathioprine; systemic
2.9
9.8
46
164
RS221, ,
NOMESCO Finland
5.0
9.8
21
43
V03AE02
ATC
sevelamer; oral
20.3
9.8
14
7
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.8
9.8
151
886
WZC30
NOMESCO Finland
Teaching
1.8
9.8
161
965
A10AC01
ATC
insulin (human); parenteral
2.2
9.8
80
374
J01EA01
ATC
trimethoprim; systemic
1.7
9.7
240
1610
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.0
9.7
106
555
QCH00
NOMESCO Finland
Avulsion of finger nail
55.6
9.7
11
*
RJ521, ,
NOMESCO Finland
55.6
9.7
11
*
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.8
9.6
156
930
Z49.2
ICD-10 Finland
Other dialysis
11.5
9.6
17
15
R4180
NOMESCO Finland
Podiatric therapy
4.7
9.6
22
48
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.5
9.5
58
238
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.5
9.5
389
2941
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
17.7
9.4
14
8
RJ425, ,
NOMESCO Finland
30.3
9.4
12
*
R50.9
ICD-10 Finland
Fever, unspecified
1.8
9.4
147
866
RJ520, ,
NOMESCO Finland
+∞
9.4
9
*
D07AB08
ATC
desonide; topical
2.0
9.3
107
569
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
8.8
9.3
19
22
H04AA01
ATC
glucagon; nasal, parenteral
3.5
9.3
31
90
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
2.5
9.2
59
247
SPAT1255
SPAT
Intravenous administration of medicine
2.4
9.2
65
285
D05AX52
ATC
calcipotriol, combinations; topical
2.5
9.1
55
224
S97
ICPC
Chronic ulcer skin
2.4
9.1
64
280
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
11.6
9.1
16
14
M25.5
ICD-10 Finland
Pain in joint
1.6
9.0
323
2361
A10AE04
ATC
insulin glargine; parenteral
2.0
9.0
96
497
N30.0
ICD-10 Finland
Acute cystitis
1.7
9.0
169
1050
S21
ICPC
Skin texture symptom/complaint
1.8
9.0
149
894
RJ412, ,
NOMESCO Finland
18.8
8.9
13
7
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.6
8.9
53
214
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.9
8.9
112
615
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.0
8.9
39
134
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.0
8.9
100
528
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
8.8
345
2570
SPAT1249
SPAT
Treatment-related counselling outside office
1.5
8.8
359
2698
L28
ICPC
Limited function/disability (L)
1.7
8.8
168
1049
H04.10
ICD-10 Finland
Dry eye syndrome
1.9
8.8
120
678
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
1.9
8.7
125
718
D22.7
ICD-10 Finland
Melanocytic naevi of lower limb, including hip
3.8
8.7
26
70
CKC12
NOMESCO Finland
Photocoagulation of retina
2.7
8.6
46
176
D05BB02
ATC
acitretin; oral
3.7
8.6
27
75
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
8.6
258
1808
D02AE01
ATC
carbamide; topical
2.3
8.6
65
294
JN3AD
NOMESCO Finland
Abdominal CT examination
1.9
8.5
123
707
Z3231
NOMESCO Finland
Registered nurse
1.6
8.4
239
1651
H13
ICPC
Plugged feeling ear
1.7
8.4
175
1118
J01AA02
ATC
doxycycline; systemic
1.6
8.4
701
6105
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.8
8.3
42
156
70309
ICD-8 Finland
Diseases of nail, Unspecified
+∞
8.3
8
*
L60.5
ICD-10 Finland
Yellow nail syndrome
+∞
8.3
8
*
N02BE01
ATC
paracetamol; systemic, rectal
1.9
8.3
838
7647
A06AD11
ATC
lactulose; oral
1.8
8.3
121
697
E87.5
ICD-10 Finland
Hyperkalaemia
4.1
8.3
22
54
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
7.2
8.3
19
27
S76
ICPC
Skin infection other
2.4
8.3
56
241
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
3.2
8.2
32
103
137
Kela drug reimbursment
Uraemia requiring dialysis
8.2
8.1
17
21
QDH05
NOMESCO Finland
Correction of deformity of toe nail
33.7
8.1
10
*
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
17.3
8.1
12
7
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.9
8.1
99
539
H25.8
ICD-10 Finland
Other senile cataract
2.0
8.1
89
467
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.4
8.1
56
244
B05DA
ATC
Isotonic solutions
10.1
8.0
15
15
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.9
8.0
108
606
L04AA01
ATC
[U] ciclosporin
6.4
8.0
20
32
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
8.0
183
1197
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
7.3
8.0
18
25
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
3.4
8.0
28
84
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.1
7.9
32
105
H3603, E103,
ICD-10 Finland
7.8
7.9
17
22
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
7.8
279
2026
L40.5
ICD-10 Finland
Arthropathic psoriasis
4.1
7.8
21
52
SPAT1312
SPAT
General health counselling
1.5
7.8
281
2044
A10AB04
ATC
insulin lispro; parenteral
2.9
7.8
37
133
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.8
7.8
113
649
M79.6
ICD-10 Finland
Pain in limb
1.5
7.8
413
3256
L71.9
ICD-10 Finland
Rosacea, unspecified
3.9
7.7
22
57
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
15.2
7.7
12
8
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
7.7
240
1690
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.0
7.7
91
489
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
7.5
7.7
17
23
K65.0
ICD-10 Finland
Acute peritonitis
7.5
7.7
17
23
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
7.7
268
1936
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.9
7.7
96
526
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.2
7.7
64
302
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.4
7.7
54
237
R06AE07
ATC
cetirizine; oral
1.5
7.7
404
3178
N18.0
ICD-10 Finland
End-stage renal disease
8.1
7.6
16
20
Z00.8
ICD-10 Finland
Other general examinations
2.0
7.6
85
448
M13.9
ICD-10 Finland
Arthritis, unspecified
2.1
7.6
72
357
SPAT1081
SPAT
Cardiorespiratory global assessment
2.4
7.6
50
213
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
3.4
7.6
26
77
D07AC13
ATC
mometasone; topical
1.5
7.6
257
1845
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.7
7.6
39
147
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.1
7.6
71
351
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.2
7.5
64
304
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
7.2
7.5
17
24
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
2.9
7.5
35
125
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
3.7
7.5
23
63
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
3.4
7.4
26
78
SPAT1229
SPAT
Assessment of need for aid
2.1
7.4
66
320
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.5
7.4
47
197
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.0
7.3
76
390
70308
ICD-8 Finland
Diseases of nail, Alii definiti
+∞
7.3
7
*
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.1
7.3
66
322
L30.3
ICD-10 Finland
Infective dermatitis
2.6
7.3
40
156
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.7
7.3
132
811
L82
ICD-10 Finland
Seborrhoeic keratosis
1.6
7.3
175
1159
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.9
7.2
95
530
SPAT1325
SPAT
Vaccination
1.5
7.2
280
2066
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
2.7
7.2
39
151
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.4
7.2
49
212
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.9
7.1
92
509
J01DA09
ATC
[U] cefadroxil
1.5
7.1
233
1655
E000006, ,
ATC
2.1
7.1
66
325
RD210, ,
NOMESCO Finland
3.8
7.1
21
56
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.2
7.1
59
278
R05
ICD-10 Finland
Cough
1.6
7.1
198
1358
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.4
7.1
47
201
C05AA08
ATC
fluocortolone; rectal, topical
1.8
7.1
121
731
XCK10
NOMESCO Finland
Photography of fundus of eye
1.9
7.0
84
453
WZC00, ,
SPAT
1.7
7.0
140
882
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
2.6
7.0
40
159
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
3.9
7.0
20
52
A02BC03
ATC
lansoprazole; oral
1.5
7.0
246
1776
C07AB07
ATC
bisoprolol; oral
1.4
7.0
402
3200
A10AA01, ,
ATC
2.9
7.0
31
108
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
3.5
6.9
23
67
B07.9
ICD-10 Finland
Verruca simplex
2.6
6.8
38
149
Z49.0
ICD-10 Finland
Preparatory care for dialysis
6.8
6.8
16
24
L72.1
ICD-10 Finland
Trichilemmal cyst
2.3
6.8
49
217
A02BC01
ATC
omeprazole; systemic
1.5
6.8
232
1663
RS340, ,
NOMESCO Finland
40.3
6.8
8
*
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.7
6.7
143
916
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.7
6.7
34
127
H28.0*E10.3
ICD-10 Finland
Other specified diabetes mellitus - Diabetic cataract
22.7
6.7
9
*
H02AB04
ATC
methylprednisolone; systemic
1.7
6.7
126
782
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.2
6.7
57
272
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.1
6.6
62
306
L40.9
ICD-10 Finland
Psoriasis, unspecified
4.1
6.6
18
45
L21.8
ICD-10 Finland
Other seborrhoeic dermatitis
5.5
6.6
18
33
PHM99
NOMESCO Finland
Endovenous obliteration of other vein
3.2
6.6
26
84
C02AC05
ATC
moxonidine; oral
2.5
6.6
42
176
N18
ICPC
Paralysis/weakness
3.4
6.6
23
69
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.0
6.6
69
356
XCD20
NOMESCO Finland
Photoangiography of eye
4.2
6.6
17
41
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.5
6.6
277
2072
D07XC01
ATC
betamethasone; topical
1.8
6.5
103
607
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.8
6.5
106
630
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
10.1
6.5
12
12
QDE99
NOMESCO Finland
Other excision or repair of lesion of skin of lower limb
10.1
6.5
12
12
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
6.5
345
2693
R11
ICD-10 Finland
Nausea and vomiting
1.9
6.5
88
496
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.5
6.5
209
1479
H11.3
ICD-10 Finland
Conjunctival haemorrhage
2.4
6.4
44
191
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.2
6.4
54
256
H3601, E103,
ICD-10 Finland
6.6
6.3
15
23
L01BA01
ATC
methotrexate; systemic
2.6
6.3
35
137
B05DB
ATC
Hypertonic solutions
8.2
6.3
13
16
SPAT1252
SPAT
Overall medication plan or its review
2.1
6.3
62
312
K59.09
ICD-10 Finland
Constipation, unspecified
2.0
6.3
63
319
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
6.0
6.3
16
27
L12
ICPC
Hand/finger symptom/complaint
1.6
6.3
171
1162
E10
ICD-10 Finland
Type 1 diabetes mellitus
3.3
6.3
23
71
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.9
6.3
73
390
CL2S4
NOMESCO Finland
Ocular fundus photography for diabetic retinopathy screening
2.9
6.3
29
103
QDA25
NOMESCO Finland
Destruction of lesion of skin of lower limb
11.1
6.3
11
10
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
6.3
479
3983
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.5
6.3
37
150
L03
ICPC
Low back symptom/complaint
1.5
6.2
266
1990
D07CC01
ATC
betamethasone and antibiotics; topical
1.7
6.2
115
709
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
3.7
6.2
19
52
H29
ICPC
Ear symptom/complaint other
1.7
6.2
110
671
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.8
6.2
102
609
M05BA04
ATC
alendronic acid; oral
1.9
6.2
71
378
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
6.2
380
3042
T89
ICPC
Diabetes insulin dependent
2.3
6.1
44
195
B34.9
ICD-10 Finland
Viral infection, unspecified
2.7
6.1
31
116
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.8
6.1
99
588
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
2.0
6.1
61
309
D09AB01
ATC
zinc bandage without supplements; topical
3.8
6.1
18
48
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
12.6
6.1
10
8
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.7
6.0
100
599

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
352
1067
4.67
107.64
1.9
1.4
—
—
—
0
0
204
963
2.43
25.20
2.3
1.6
—
—
—
0
0
600
4414
1.99
22.03
9.7
6.3
1.82
1.94
e9/l
2.20
541
3910
414
2710
1.94
21.27
4.2
2.5
57.57
63.59
u/l
0.96
386
2510
515
3624
1.93
21.27
6.7
4.9
35.96
36.03
g/l
0.10
487
3422
602
4477
1.95
20.89
9.9
6.5
0.18
0.19
e9/l
0.70
537
3934
585
4327
1.93
20.41
9.7
6.2
0.57
0.57
e9/l
0.07
518
3731
585
4335
1.92
20.21
9.8
6.2
0.04
0.04
e9/l
0.34
520
3740
227
1223
2.13
19.96
1.5
1.3
461.43
525.69
titre
0.24
56
267
536
3879
1.88
19.71
3.2
2.5
76.60
76.54
nmol/l
0.02
500
3521
633
4850
1.93
19.33
12.9
9.6
4.00
4.05
e9/l
0.22
571
4243
769
6367
2.13
17.98
11.9
8.1
79.14
78.36
u/l
0.13
741
6046
335
2140
1.88
17.76
1.5
1.3
1.01
1.79
u/ml
1.29
117
575
91
341
2.85
17.70
1.2
1.2
—
—
—
0
0
583
4432
1.83
17.30
7.9
6.6
10.52
11.13
umol/l
0.68
556
4230
263
1566
1.94
17.19
1.4
1.3
13.93
11.59
u/ml
0.20
123
591
467
3328
1.80
17.16
2.4
2.1
—
—
—
0
0
275
1671
1.91
16.86
1.5
1.3
43.84
29.57
iu/ml
0.34
71
521
538
4020
1.79
16.62
9.7
6.3
57.55
56.87
%
0.69
522
3856
535
3997
1.78
16.48
9.7
6.5
8.74
8.73
%
0.04
513
3762
545
4095
1.78
16.45
9.7
6.4
27.95
28.30
%
0.34
527
3893
549
4148
1.77
16.12
12.2
7.3
1.22
1.21
mmol/l
0.74
481
3598
532
3987
1.77
16.03
9.7
6.4
2.70
2.85
%
0.93
508
3746
367
2478
1.79
15.83
5.7
3.8
0.00
0.01
estimate
1.54
141
868
527
3983
1.73
15.00
9.8
6.5
0.70
0.69
%
0.17
503
3737
669
5451
1.78
14.16
6.4
4.5
1116.08
1094.39
e6/l
0.01
12
77
345
2356
1.73
13.87
1.8
1.7
20.09
20.49
nmol/l
0.21
306
2009
225
1358
1.86
13.71
4.0
2.4
12.87
13.33
umol/l
0.49
210
1266
429
3123
1.69
13.53
3.9
3.5
689.62
47.91
ng/l
0.48
293
2128
574
4532
1.68
13.09
5.5
3.7
0.00
4.86
estimate
1.08
150
935
319
2159
1.72
13.09
4.8
4.2
—
—
—
0
0
569
4492
1.67
12.89
5.4
3.7
0.00
0.00
estimate
0.50
147
911
196
1158
1.87
12.67
3.2
2.0
—
—
—
0
0
316
2151
1.71
12.60
3.2
2.2
2.78
2.82
mg/l
0.11
286
1853
142
758
2.03
12.35
5.4
4.6
0.92
1.07
%
0.28
44
237
196
1168
1.86
12.30
4.0
2.4
21.55
23.22
%
1.06
182
1096
574
4571
1.65
12.30
5.5
3.7
0.03
0.36
estimate
0.47
135
881
208
1264
1.83
12.26
4.0
2.4
2.36
2.33
g/l
0.34
192
1180
482
3682
1.63
12.14
15.3
13.5
1.25
1.20
inr
0.42
420
3070
147
801
1.99
12.06
2.5
2.1
0.03
0.03
estimate
0.04
38
166
601
4855
1.66
12.05
7.8
5.3
6.86
6.64
mmol/l
1.46
570
4584
195
1169
1.84
11.98
2.8
2.4
136.99
116.38
ug/g
0.24
163
932
895
8197
2.80
11.76
23.4
14.8
21.33
23.14
mg/l
1.03
780
6708
66
260
2.65
11.66
1.3
1.2
8.07
5.78
u/ml
—
7
40
133
708
2.02
11.63
17.2
7.3
10.41
9.11
mmol/l
1.23
128
681
133
722
1.98
10.99
5.6
4.8
0.31
0.11
%
0.96
35
199
135
737
1.97
10.97
6.9
5.0
0.08
0.17
%
0.60
37
185
303
2101
1.65
10.97
4.4
2.7
337.85
335.99
umol/l
0.11
270
1879
133
725
1.97
10.85
5.7
4.5
0.64
0.70
%
0.11
39
225
277
1883
1.67
10.80
1.5
1.5
2.12
2.38
g/l
2.25
193
1186
64
259
2.58
10.72
1.3
1.2
1.76
2.82
u/ml
—
5
24
112
581
2.05
10.49
5.4
3.1
—
—
—
0
0
90
429
2.21
10.47
2.8
2.2
0.00
1.90
estimate
0.50
38
132
286
1977
1.64
10.38
6.9
4.6
—
—
—
0
0
79
358
2.32
10.36
1.2
1.2
0.24
1.39
u/ml
—
5
22
119
634
2.00
10.35
5.1
3.6
113.09
80.88
ng/l
1.41
106
565
101
508
2.11
10.26
1.4
1.4
45.10
42.48
au/ml
—
6
49
392
2936
1.57
10.12
4.2
3.4
2.35
2.36
mmol/l
1.41
361
2685
108
560
2.05
10.12
2.6
2.5
26.57
21.35
au/ml
—
9
58
179
1101
1.77
9.96
10.7
5.5
1.12
1.03
mmol/l
2.17
167
1027
189
1186
1.74
9.80
1.4
1.2
—
—
—
0
0
442
3426
1.55
9.66
5.4
3.6
0.00
0.04
estimate
3.48
131
764
377
2821
1.56
9.65
9.8
6.4
—
—
—
0
0
351
2585
1.57
9.63
4.2
3.0
—
—
—
0
0
344
2539
1.56
9.27
2.6
2.2
191.19
235.01
u/l
0.33
327
2411
21
29
7.38
9.25
25.3
34.0
110.67
143.96
ug/l
1.14
12
24
755
6647
1.68
9.15
5.8
4.4
14.75
14.72
pmol/l
0.11
713
6144
470
3723
1.52
9.10
10.8
6.7
1.22
1.21
mmol/l
0.23
436
3449
262
1822
1.61
9.09
4.0
2.6
4.88
6.35
e6/l
0.76
242
1658
91
462
2.07
9.02
1.2
1.1
—
147.60
titre
—
0
10
135
796
1.81
8.59
2.1
2.3
0.22
0.22
g/l
0.06
125
749
510
4146
1.50
8.50
4.2
3.0
103.10
113.92
ug/l
0.83
482
3874
321
2378
1.53
8.31
4.0
3.1
1208.13
1005.81
ng/l
0.58
279
2015
333
2487
1.52
8.29
6.8
4.0
7.39
7.40
ph
0.70
259
1795
273
1971
1.54
7.88
2.4
1.8
0.99
1.16
mg/l
0.74
205
1510
74
366
2.11
7.86
2.0
2.1
9.07
7.73
iu/ml
0.15
16
87
224
1552
1.58
7.73
4.2
2.8
510.55
526.98
mosm/kgh2o
0.51
206
1360
119
703
1.79
7.51
2.1
2.9
10.02
10.80
g/l
0.82
108
655
87
467
1.95
7.39
1.4
1.2
—
—
—
0
0
236
1670
1.55
7.39
1.8
1.7
474.69
36227119.82
pmol/l
1.93
200
1394
66
320
2.14
7.39
1.1
1.1
—
—
—
0
0
163
1058
1.65
7.32
4.0
3.2
4.50
5.16
e9/l
0.55
148
927
915
8690
2.78
7.15
29.3
19.1
80.39
74.70
umol/l
3.07
908
8600
445
3614
1.44
6.90
4.7
3.3
6.34
6.21
ph
1.78
266
2026
480
3953
1.44
6.89
3.1
2.7
—
—
estimate
—
0
0
36
138
2.67
6.78
1.4
1.3
24.65
25.28
u/l
0.04
30
117
886
8325
2.06
6.73
26.4
17.4
139.61
139.73
mmol/l
0.80
873
8178
343
2663
1.45
6.73
4.7
3.3
64.69
77.03
e6/l
0.10
284
2022
44
188
2.41
6.64
3.2
3.0
1.30
1.53
mmol/l
1.31
44
183
910
8652
2.48
6.51
17.5
11.8
25.29
26.07
u/l
0.81
895
8432
837
7741
1.72
6.51
6.9
5.4
1.86
1.90
mu/l
0.44
793
7228
18
46
3.97
6.46
3.2
2.9
15.33
16.71
%
0.86
18
46
111
675
1.73
6.33
2.8
2.9
65.23
67.15
g/l
1.85
106
628
128
810
1.67
6.31
6.8
4.0
7.38
7.38
ph
0.18
92
444
443
3634
1.41
6.30
2.2
2.1
100.43
96.98
pmol/l
0.82
244
1899
885
8339
2.00
6.24
26.7
17.5
3.98
3.96
mmol/l
1.37
871
8177
59
294
2.07
6.19
1.2
1.2
—
—
—
0
0
229
1669
1.49
6.11
2.8
2.8
2.43
2.45
mmol/l
2.72
216
1511
123
782
1.66
5.95
7.6
3.9
1.76
1.87
mmol/l
0.14
112
671
104
634
1.72
5.88
2.5
2.4
6.68
7.36
ug/l
0.13
93
565
106
651
1.71
5.84
4.5
3.6
1.23
1.23
mmol/l
0.13
93
566
109
676
1.69
5.79
4.0
2.8
68.62
71.82
e9/l
0.50
89
496
316
2475
1.42
5.71
4.5
3.2
0.00
0.05
estimate
0.86
124
755
382
3093
1.40
5.68
5.3
3.9
70.73
97.07
e6/l
0.56
291
2143
127
833
1.61
5.42
3.4
2.1
333.33
381.16
nmol/l
2.23
120
789
200
1451
1.48
5.40
1.7
1.7
—
—
—
0
0
450
3766
1.37
5.38
17.5
11.1
0.00
0.00
e9/l
0.69
376
3104
178
1263
1.50
5.36
1.8
1.7
1349.82
1204.27
nmol/l
1.07
130
962
295
2304
1.41
5.35
4.5
3.2
0.18
0.43
e6/l
4.34
243
1674
118
763
1.62
5.34
5.7
3.8
7.36
7.36
ph
0.11
91
553
228
1708
1.44
5.20
2.0
1.9
—
—
—
0
0
92
562
1.71
5.17
1.5
1.8
1.18
1.35
g/l
0.68
84
523
131
877
1.57
5.13
3.6
2.8
1.83
1.83
%
0.03
118
796
52
267
2.00
5.07
1.6
1.4
248.27
291.11
ug/g
0.73
30
156
47
234
2.06
4.98
1.5
1.4
9.29
9.81
u/l
0.12
40
193
28
112
2.55
4.91
1.3
1.3
—
73.83
—
0
8
33
143
2.36
4.89
1.3
1.7
0.51
0.83
g/l
1.23
27
116
39
182
2.19
4.87
1.2
1.3
219.22
232.75
u/ml
0.13
27
110
104
668
1.63
4.84
2.7
2.3
0.31
0.57
e6/l
0.73
99
639
153
1074
1.51
4.83
1.7
1.5
—
—
—
0
0
28
113
2.52
4.83
1.7
1.3
—
—
—
0
0
824
7703
1.55
4.80
7.7
6.1
40.34
39.01
mmol/mol
3.11
785
7267
334
2703
1.36
4.79
4.5
4.2
14.45
8.84
mg/mmol
0.59
232
1662
329
2659
1.36
4.75
3.9
3.5
62.32
47.82
mg/l
0.38
229
1691
22
79
2.83
4.74
1.3
1.3
2.58
2.90
g/l
0.49
17
57
22
79
2.83
4.74
1.3
1.3
5.72
7.32
g/l
1.11
17
58
22
79
2.83
4.74
1.3
1.3
0.34
0.40
g/l
0.39
17
58
22
79
2.83
4.74
1.3
1.3
—
—
—
0
0
926
8967
2.81
4.67
35.3
22.6
256.11
253.14
e9/l
0.64
910
8810
926
8969
2.80
4.63
35.1
22.6
91.02
90.93
fl
0.23
917
8889
926
8971
2.79
4.59
36.2
23.2
40.29
40.40
%
0.33
918
8883
926
8971
2.79
4.59
35.1
22.5
30.24
30.28
pg
0.23
917
8889
926
8971
2.79
4.59
35.2
22.6
4.46
4.50
e12/l
1.44
909
8787
926
8974
2.77
4.53
35.3
22.7
6.66
6.66
e9/l
0.03
910
8785
20
70
2.90
4.51
1.4
1.1
—
—
—
0
0
926
8975
2.76
4.51
35.5
22.8
133.89
135.26
g/l
2.14
918
8891
138
963
1.51
4.47
1.3
1.3
—
—
—
0
0
350
2877
1.34
4.46
4.1
3.4
7.35
7.65
mmol/l
0.55
314
2462
34
157
2.21
4.38
1.4
1.4
150.83
161.62
au/ml
—
6
38
188
1402
1.43
4.33
5.0
3.5
0.83
0.82
mmol/l
0.65
176
1335
888
8488
1.79
4.33
19.6
13.1
—
—
—
0
0
25
101
2.52
4.32
1.5
1.5
20.38
25.96
ng/l
0.70
25
101
108
723
1.56
4.24
1.2
1.2
—
—
—
0
0
84
533
1.63
4.12
4.8
3.4
4.29
4.57
pmol/l
1.22
78
470
16
52
3.11
4.10
3.3
2.7
9.12
8.13
mmol/l
0.41
16
52
352
2938
1.32
3.92
3.8
3.3
30.98
32.24
u/l
0.23
334
2781
53
300
1.81
3.92
1.2
1.3
—
—
—
0
0
131
932
1.47
3.86
11.2
9.4
5.10
5.10
kpa
0.02
126
907
131
932
1.47
3.86
11.3
9.4
11.93
12.24
kpa
0.34
126
909
638
5781
1.32
3.83
3.9
3.3
46.49
46.48
u/l
0.00
605
5476
35
174
2.05
3.78
1.2
1.4
—
—
—
0
0
14
40
3.54
3.61
1.3
1.4
141.50
155.57
mmol/24h
0.16
14
40
252
2027
1.33
3.59
5.6
3.7
1.02
1.02
kg/l
0.28
172
1336
89
595
1.55
3.53
2.6
2.3
10.98
13.07
nmol/l
1.51
83
541
25
112
2.27
3.50
1.1
1.2
—
—
—
0
0
34
173
2.00
3.47
2.5
3.5
27.46
34.42
umol/l
2.15
28
157
129
935
1.44
3.46
11.5
9.4
7.41
7.42
ph
0.41
78
529
12
32
3.78
3.39
3.2
1.4
—
—
—
0
0
20
84
2.41
3.24
1.8
1.8
51.19
60.46
%
0.45
15
61
252
2056
1.31
3.21
2.9
2.4
—
—
—
0
0
30
151
2.02
3.18
3.2
3.2
7.82
7.41
mmol/l
0.23
30
146
816
7739
1.40
3.16
4.9
4.2
1.28
1.28
mmol/l
0.05
764
7167
861
8247
1.51
3.16
6.5
5.7
2.63
2.75
mmol/l
3.61
818
7724
853
8156
1.48
3.15
5.9
5.0
4.58
4.69
mmol/l
2.76
810
7667
850
8123
1.47
3.13
5.7
4.9
1.49
1.49
mmol/l
0.12
802
7590
84
571
1.52
3.11
2.2
2.5
—
—
—
0
0
9
21
4.32
3.00
3.3
1.3
—
—
—
0
0
321
2727
1.27
2.94
2.9
2.4
—
—
—
0
0
32
170
1.91
2.93
7.3
2.9
10.98
8.33
pmol/l
1.02
32
170
180
1425
1.33
2.82
3.5
2.9
0.68
1.06
e6/l
1.02
116
742
89
628
1.46
2.77
1.2
1.2
87.66
142.97
u/ml
1.11
34
251
41
241
1.73
2.75
1.5
1.1
—
—
—
0
0
24
119
2.04
2.68
1.0
1.2
—
—
—
0
0
122
919
1.38
2.65
11.8
9.5
1.31
0.96
mmol/l
0.44
99
767
29
156
1.89
2.59
1.0
1.1
—
—
—
0
0
68
462
1.51
2.56
6.3
6.1
—
—
—
0
0
5
7
7.17
2.55
1.2
1.3
—
—
—
0
0
46
286
1.64
2.53
6.6
3.9
749.95
305.90
mg/l
0.37
22
118
300
2567
1.25
2.52
8.1
6.1
—
—
—
0
0
95
694
1.41
2.48
15.9
10.0
—
—
—
0
0
8
21
3.83
2.46
1.1
1.1
—
—
—
0
0
76
534
1.46
2.44
5.6
3.9
7.40
7.42
ph
1.80
61
446
83
595
1.43
2.40
1.5
1.2
—
—
—
0
0
9
27
3.36
2.39
6.7
3.4
—
—
—
0
0
51
331
1.57
2.37
2.6
2.2
15387.15
5657.05
u/l
0.37
16
141
28
154
1.84
2.36
1.1
1.1
—
—
—
0
0
10
33
3.05
2.36
2.6
1.7
33.41
55.21
ug/l
—
10
33
26
141
1.87
2.29
2.6
3.7
4.40
4.25
e9/l
0.09
26
141
7
18
3.91
2.25
3.6
1.4
—
—
—
0
0
57
387
1.50
2.19
2.2
2.3
—
—
—
0
0
114
882
1.33
2.11
1.7
1.5
—
—
—
0
0
11
43
2.58
2.08
3.5
3.2
572.45
827.02
u/ml
0.66
11
43
76
552
1.41
2.08
4.1
3.2
169.78
168.78
ng/l
0.01
67
500
23
125
1.86
2.04
1.4
1.8
—
—
—
0
0
14
63
2.24
2.01
1.5
1.8
46.90
40.63
%
1.05
14
63
6
16
3.77
1.93
1.3
2.3
—
—
—
0
0
54
376
1.46
1.87
5.7
4.1
—
—
—
0
0
19
100
1.92
1.86
2.3
2.3
—
—
—
0
0
822
7934
1.28
1.79
6.0
5.0
6.04
5.89
mmol/l
1.85
773
7339
116
923
1.29
1.78
1.8
1.7
—
—
—
0
0
15
75
2.02
1.70
1.3
1.1
94.53
106.45
pmol/l
0.42
15
75
20
111
1.82
1.69
2.9
1.5
—
—
—
0
0
20
111
1.82
1.69
2.9
1.5
—
—
—
0
0
20
111
1.82
1.69
2.9
1.5
—
—
—
0
0
20
111
1.82
1.69
2.9
1.5
—
—
—
0
0
729
6960
1.21
1.67
26.4
18.4
13.70
13.55
%
2.01
724
6877
135
1106
1.26
1.65
1.3
1.3
—
—
—
0
0
23
135
1.72
1.63
1.5
1.2
3.69
4.68
u/ml
0.21
13
60
12
56
2.16
1.61
2.7
2.9
42.43
40.93
%
—
7
34
54
389
1.41
1.59
3.9
3.1
1.02
1.02
ratio
0.17
54
367
36
239
1.53
1.59
2.7
3.6
1.53
2.52
ratio
1.21
25
135
26
160
1.64
1.57
2.6
4.0
—
—
—
0
0
10
44
2.29
1.56
1.0
1.1
1701.90
1494.89
miu/ml
—
10
44
30
192
1.58
1.55
1.3
1.4
6.09
10.98
e6/l
0.40
23
143
30
195
1.56
1.47
1.3
1.4
712.21
773.77
e6/l
0.02
24
152
28
179
1.58
1.47
4.5
4.0
—
—
—
0
0
29
188
1.56
1.44
2.5
3.4
60.14
58.32
%
0.34
29
188
118
969
1.25
1.43
2.2
2.8
5.51
7.95
umol/l
1.79
105
856
25
157
1.61
1.41
1.2
1.5
—
10.40
—
0
5
17
96
1.78
1.39
3.4
2.7
1.68
1.41
g/24h
—
10
63
64
487
1.34
1.39
14.2
4.3
24.23
24.32
mmol/l
0.11
64
481
29
190
1.54
1.38
2.7
2.3
98.58
105.75
ug/min
0.05
19
113
275
2457
1.17
1.37
3.6
2.9
0.00
0.05
—
5
42
5
17
2.95
1.36
72.8
8.2
6.18
4.94
kpa
—
5
17
34
232
1.48
1.36
1.3
1.7
—
—
—
0
0
10
47
2.14
1.34
1.2
1.6
—
—
—
0
0
120
998
1.23
1.31
1.4
1.5
—
—
—
0
0
24
154
1.57
1.27
1.2
1.1
57.52
19.60
au/ml
—
6
46
41
295
1.41
1.26
6.3
4.5
24.26
25.09
mmol/l
1.33
35
277
43
313
1.39
1.24
3.5
2.0
20.58
21.01
s
0.34
38
285
57
435
1.33
1.23
1.3
1.4
24.90
28.91
iu/l
0.43
52
374
15
85
1.78
1.23
3.5
3.9
—
—
—
0
0
11
56
1.98
1.22
1.5
1.8
252.25
91.20
ng/l
0.45
11
56
21
323
0.64
1.21
1.2
1.1
1.40
1.56
g/l
2.22
21
323
22
332
0.65
1.16
1.2
1.2
0.88
0.91
g/l
0.44
22
332
26
174
1.51
1.16
1.5
1.7
—
—
—
0
0
23
343
0.66
1.15
3.2
1.8
—
—
—
0
0
58
738
0.77
1.12
1.7
1.8
3.27
3.48
mmol/l
0.84
33
533
7
30
2.34
1.12
1.1
1.3
—
—
—
0
0
98
818
1.22
1.06
3.6
4.6
3.25
25.11
ug/l
1.46
77
676
17
106
1.61
1.03
1.4
2.1
32.41
32.69
pg
0.09
17
106
68
838
0.80
1.03
1.3
1.4
—
—
—
0
0
9
47
1.92
1.02
5.4
3.2
0.56
0.87
index
—
9
47
17
107
1.60
1.00
1.5
1.1
—
—
—
0
0
13
77
1.70
0.95
1.2
1.3
0.06
0.89
u/ml
—
7
33
275
2518
1.13
0.95
1.5
1.5
—
—
—
0
0
26
362
0.71
0.94
2.9
1.8
—
—
—
0
0
11
62
1.78
0.94
1.2
1.1
190.18
217.34
mg/l
0.61
11
53
16
245
0.65
0.94
9.2
2.4
—
—
—
0
0
18
117
1.55
0.94
3.8
2.8
—
—
—
0
0
85
710
1.22
0.93
1.6
1.4
—
—
—
0
0
6
27
2.23
0.93
1.0
1.1
—
—
—
0
0
6
27
2.23
0.93
1.0
1.0
—
—
—
0
0
13
78
1.68
0.92
5.5
2.5
—
—
—
0
0
25
176
1.43
0.91
1.2
1.4
—
—
—
0
0
5
103
0.48
0.89
4.8
2.4
—
—
—
0
0
177
1582
1.15
0.88
4.5
3.9
839.23
358.50
ng/l
0.48
135
1185
84
708
1.20
0.86
1.4
1.4
—
—
—
0
0
12
72
1.68
0.85
1.2
1.2
—
—
—
0
0
13
80
1.63
0.85
1.0
1.1
—
—
—
0
0
33
248
1.34
0.84
1.3
1.3
—
—
—
0
0
27
364
0.73
0.83
2.9
1.8
—
—
—
0
0
11
65
1.70
0.82
1.2
1.1
—
—
—
0
0
27
362
0.74
0.80
2.6
1.7
—
—
—
0
0
23
164
1.41
0.80
1.3
1.2
100.62
28.32
u/l
0.41
23
143
6
33
1.82
0.79
2.3
3.2
—
—
—
0
0
27
199
1.37
0.79
1.9
2.4
126.90
130.59
g/l
0.42
20
163
27
360
0.74
0.78
2.9
1.8
—
—
—
0
0
12
186
0.64
0.77
1.2
1.5
1.36
1.28
mm
—
6
136
20
141
1.43
0.75
1.3
1.1
0.48
2.74
u/ml
—
7
65
12
76
1.59
0.72
1.2
1.2
—
—
—
0
0
14
93
1.51
0.69
1.1
1.3
—
—
—
0
0
13
192
0.67
0.68
1.3
1.6
—
—
—
0
0
11
70
1.58
0.65
1.3
1.2
—
—
—
0
0
32
251
1.28
0.65
2.0
2.0
4.77
4.52
iu/l
0.04
13
97
13
188
0.69
0.63
1.2
1.5
—
—
—
0
0
28
217
1.30
0.62
8.7
4.5
65.41
59.26
%
0.79
28
208
5
30
1.67
0.61
1.2
1.1
—
—
—
0
0
5
30
1.67
0.61
1.0
1.9
41.72
42.26
g/l
—
5
30
79
687
1.16
0.61
2.8
2.3
5.91
6.09
ph
1.07
52
460
22
289
0.76
0.61
3.2
1.8
—
—
—
0
0
0
21
0.00
0.60
0.0
3.8
—
46.76
—
0
21
0
21
0.00
0.60
0.0
7.5
—
8.48
—
0
21
10
64
1.57
0.58
2.2
2.4
1015.10
916.42
mg
—
10
64
0
23
0.00
0.58
0.0
3.8
—
5.78
—
0
23
6
37
1.63
0.55
1.2
1.3
7.40
7.37
ph
—
6
25
13
90
1.45
0.55
4.7
3.3
59.54
56.14
%
0.26
13
85
46
386
1.20
0.54
2.8
2.0
—
—
—
0
0
374
3569
1.08
0.54
2.2
1.9
1.40
1.35
mmol/l
0.61
322
3035
9
62
1.46
0.53
1.2
1.7
12.30
12.05
umol/l
—
9
55
11
158
0.69
0.53
5.2
2.1
—
—
—
0
0
22
170
1.30
0.52
3.8
2.7
90.18
89.78
%
0.10
22
164
6
40
1.50
0.51
2.3
2.8
—
—
—
0
0
16
118
1.36
0.50
1.2
1.0
0.09
0.29
u/ml
—
5
35
6
41
1.47
0.50
1.8
2.3
1.95
2.18
ug/l
—
6
35
144
1325
1.10
0.48
3.9
3.0
2.99
2.72
e6/l
0.10
79
643
17
219
0.77
0.44
1.3
1.1
—
—
—
0
0
15
113
1.33
0.43
8.5
5.7
12.67
12.04
mg/l
0.25
15
103
5
32
1.57
0.42
2.0
1.5
25.80
30.28
%
—
5
32
8
57
1.41
0.42
1.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
0.02
—
0
16
8
59
1.36
0.41
1.1
1.7
5.92
8.25
ug/l
—
8
50
37
315
1.18
0.40
1.2
1.3
128.14
253.58
miu/ml
—
10
150
17
132
1.29
0.40
1.1
1.1
1.42
1.92
eliau/ml
—
8
56
8
60
1.34
0.40
1.1
1.3
—
—
—
0
0
26
214
1.22
0.39
2.2
1.5
10972.63
14099.29
e6/l
0.26
19
160
9
67
1.35
0.38
1.0
1.0
—
—
—
0
0
710
6982
1.07
0.37
29.4
19.0
332.35
332.24
g/l
0.11
705
6946
87
795
1.10
0.36
5.2
2.5
37.18
36.32
u/l
0.06
76
670
212
2013
1.07
0.35
6.0
5.3
2.14
2.36
ug/l
0.25
196
1820
19
153
1.25
0.35
1.1
1.1
0.08
1.39
u/ml
—
6
73
14
108
1.30
0.35
3.3
2.7
—
—
—
0
0
6
44
1.37
0.34
1.0
1.3
—
—
—
0
0
17
136
1.25
0.33
1.2
1.2
—
—
—
0
0
25
210
1.20
0.33
4.4
3.0
1.42
2.35
index
0.81
19
114
20
164
1.22
0.33
2.7
3.6
12.92
26.46
mg/l
2.43
13
108
6
47
1.28
0.32
1.2
1.4
141.35
181.70
pmol/l
—
6
47
12
92
1.31
0.32
1.3
1.1
—
—
—
0
0
107
999
1.08
0.29
1.6
1.6
—
—
—
0
0
7
56
1.25
0.29
1.4
1.3
74.00
78.64
umol/l
—
7
56
50
450
1.12
0.28
1.1
1.1
—
—
—
0
0
15
121
1.24
0.28
1.7
1.3
38.80
55.94
mu/l
0.25
15
111
31
273
1.14
0.25
3.0
2.6
—
—
—
0
0
13
105
1.24
0.25
1.4
1.3
—
—
—
0
0
9
77
1.17
0.24
1.6
1.3
7.23
6.30
mmol/l
—
9
70
39
432
0.90
0.23
1.5
1.6
1045.31
973.57
mu/l
0.28
27
367
7
95
0.73
0.22
1.0
1.1
—
—
—
0
0
5
42
1.19
0.21
2.2
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
1.76
—
0
11
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
37.60
—
0
10
5
43
1.16
0.21
1.2
1.2
—
—
—
0
0
10
80
1.25
0.20
2.3
2.2
—
—
—
0
0
10
123
0.81
0.20
1.9
1.7
—
—
—
0
0
0
14
0.00
0.20
0.0
2.8
—
—
—
0
0
0
14
0.00
0.20
0.0
2.8
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
6.33
—
0
14
22
249
0.88
0.19
1.5
1.6
50.95
60.28
ug/l
0.65
17
214
15
175
0.85
0.19
1.1
1.1
—
—
—
0
0
10
81
1.24
0.19
1.8
2.6
105.00
105.95
mmol/l
—
10
81
10
81
1.24
0.19
1.8
2.6
3.78
3.98
mmol/l
—
10
81
15
174
0.86
0.18
1.1
1.1
—
—
—
0
0
21
237
0.88
0.18
1.1
1.2
—
—
—
0
0
8
69
1.16
0.16
1.0
1.1
—
1.68
—
0
9
8
70
1.14
0.16
1.0
1.5
—
—
—
0
0
8
72
1.11
0.16
1.4
1.3
—
—
—
0
0
9
79
1.14
0.15
1.9
2.6
1.20
1.20
mmol/l
—
9
79
328
3342
0.97
0.15
3.4
3.1
—
—
—
0
0
71
679
1.05
0.12
4.8
3.8
—
—
—
0
0
10
86
1.16
0.11
1.3
1.6
—
—
—
0
0
17
154
1.11
0.10
1.5
1.4
—
—
—
0
0
23
214
1.08
0.08
1.2
1.2
—
—
—
0
0
9
85
1.06
0.07
1.4
1.2
—
—
—
0
0
48
463
1.04
0.06
1.8
1.7
—
—
—
0
0
119
1212
0.98
0.06
3.1
3.1
0.72
0.78
ug/l
0.33
82
778
40
385
1.04
0.05
1.7
1.6
0.43
0.35
mg/l
0.44
22
177
19
178
1.07
0.05
1.3
1.2
—
—
—
0
0
11
120
0.92
0.05
1.1
1.2
—
—
—
0
0
14
149
0.94
0.03
1.1
1.2
—
—
—
0
0
15
158
0.95
0.02
1.1
1.1
1.79
5.44
u/ml
—
8
83
19
186
1.02
0.00
1.2
1.1
0.42
2.51
u/ml
—
8
102
15
148
1.01
0.00
2.1
1.8
—
—
—
0
0
24
237
1.01
0.00
9.0
9.0
—
—
—
0
0
35
347
1.01
0.00
1.6
1.6
13.03
11.63
u/ml
0.05
12
79
15
155
0.97
0.00
1.1
1.1
0.36
1.69
u/ml
—
5
63
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
34.60
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
69
0.87
0.00
1.8
1.9
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
7
69
1.01
0.00
1.4
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
7
78
0.90
0.00
1.7
2.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
0.03
—
0
6
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
68.00
—
0
8
0
6
0.00
0.00
0.0
1.7
—
494.18
—
0
6
0
6
0.00
0.00
0.0
1.7
—
340.00
—
0
6
0
6
0.00
0.00
0.0
1.2
—
16.26
—
0
6
0
6
0.00
0.00
0.0
2.0
—
0.48
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
93
0.97
-0.00
1.2
1.6
—
—
—
0
0
5
51
0.98
-0.00
1.0
1.2
6.80
8.33
mm/h
—
5
51
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
-0.00
1.2
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
77.66
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
3.74
—
0
5

Mortality – FinRegistry

Association

Association between endpoint L12_NAILNAS and mortality.

Females

Parameter HR [95% CI] p-value
L12_NAILNAS 1.733 [1.42, 2.12] < 0.001
Birth year 0.994 [0.99, 1.0] 0.162

During the follow-up period (1.1.1998 — 31.12.2019), 226 out of 1906 females with L12_NAILNAS died.

Males

Parameter HR [95% CI] p-value
L12_NAILNAS 2.137 [1.7, 2.68] < 0.001
Birth year 0.988 [0.98, 1.0] 0.012

During the follow-up period (1.1.1998 — 31.12.2019), 258 out of 1445 males with L12_NAILNAS died.

Mortality risk

Mortality risk for people of age

years, who have L12_NAILNAS.

N-year risk Females Males
1 0.197% 0.395%
5 1.018% 2.492%
10 2.49% 6.655%
15 4.702% 11.997%
20 8.331% 19.587%

Relationships between endpoints

Index endpoint: L12_NAILNAS – Other and unspecified nail disorders

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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