Benign neoplasm: Urinary organ, other/unspecified

CD2_BENIGN_URINARY_NOS

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D30.7&, D30.9& Hospital discharge: ICD-9 — 223[8-9] Hospital discharge: ICD-8 — 223[8-9] Cause of death: ICD-10 — D30.7&, D30.9& Cause of death: ICD-9 — 223[8-9] Cause of death: ICD-8 — 223[8-9] 2 out of 7 registries used, show all original rules.	112
4. Check minimum number of events None	112
5. Include endpoints None	112
6. Filter based on genotype QC (FinnGen only)	98

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2

NAME	CD2_BENIGN_URINARY_NOS
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D30[7\|9]
HD_ICD_9	223[8-9]
HD_ICD_8	223[8-9]
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D30[7\|9]
COD_ICD_9	223[8-9]
COD_ICD_8	223[8-9]
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Benign neoplasm: Urinary organ, other/unspecified based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	991	579	393
Only index persons	703	426	277
Unadjusted period prevalence (%)
Whole population	0.01	0.02	0.01
Only index persons	0.01	0.02	0.01
Median age at first event (years)
Whole population	58.75	57.59	60.12
Only index persons	53.30	53.31	53.29

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	98	62	36
Unadjusted period prevalence (%)	0.02	0.02	0.02
Median age at first event (years)	49.63	45.77	56.29

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
101: Matched controls
1010

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D30.9

ICD-10 Finland

Benign neoplasm: Urinary organ, unspecified

+∞

60.7

22388

ICD-8 Finland

Benign neoplasm of kidney and other urinary organs, Other specified sites

+∞

21.6

D30.0

ICD-10 Finland

Benign neoplasm: Kidney

67.3

10.9

D30.7

ICD-10 Finland

Benign neoplasm: Other urinary organs

+∞

10.6

22399

ICD-8 Finland

Benign neoplasm of kidney and other urinary organs, Unspecified site

+∞

9.5

UKC02

NOMESCO Finland

Cystoscopy

4.1

8.7

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3032080) INR in Blood by Coagulation assay

408

1.84

2.32

14.1

12.5

1.18

1.22

inr

0.20

345

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

3.99

1.73

2.0

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

3.99

1.73

2.0

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

3.99

1.73

2.0

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

213

1.74

1.69

2.3

2.2

2.46

2.80

mg/l

0.53

187

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

378

1.64

2.4

2.1

92.46

97.91

pmol/l

0.39

176

(3027315) Oxygen [Partial pressure] in Blood

3.70

1.63

2.4

1.9

8.76

9.14

kpa

—

(3013290) Carbon dioxide [Partial pressure] in Blood

3.70

1.63

2.4

1.9

5.02

4.81

kpa

—

(40761536) Microorganisms panel - Urine sediment

2.13

1.63

5.8

3.4

—

(3030467) Casts [#/volume] in Urine by Automated count

216

1.70

1.61

3.0

3.3

0.22

0.46

e6/l

0.78

163

(1616796) Gas panel - Central venous blood

3.45

1.54

1.4

1.5

—

(3018095) Leukocytes [#/volume] in Urine

300

1.62

1.50

3.4

4.0

135.56

57.53

e6/l

0.39

217

(3002582) Erythrocytes [#/volume] in Urine

257

1.62

1.45

3.0

3.4

24.11

290.41

e6/l

0.56

204

(3024561) Albumin [Mass/volume] in Serum or Plasma

379

1.57

1.40

3.8

4.0

36.45

35.52

g/l

0.63

359

(3037522) Nuclear Ab [Titer] in Serum

115

1.80

1.37

1.4

664.00

564.29

titre

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

2.12

1.33

1.4

1.7

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.99

1.24

1.4

1.8

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

195

1.60

1.22

1.5

1.3

0.48

2.70

u/ml

—

(3010421) pH of Blood

2.57

1.16

2.4

7.42

7.43

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

121

1.70

1.16

2.8

2.9

2.83

1.00

e6/l

0.53

(36660697) Celiac disease serology panel - Serum

1.93

1.14

1.2

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

132

1.64

1.07

2.8

2.3

20.20

22.96

0.49

123

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.77

1.04

4.0

3.6

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.92

1.02

1.9

1.6

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.88

1.00

3.1

1.3

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.84

0.97

14.3

6.3

23.92

25.28

mmol/l

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

1.96

0.96

1.6

1.9

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

1.96

0.96

2.0

2.1

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

111

1.64

0.95

2.9

117.26

2.88

e6/l

—

(3049717) Cytology report of Urine Cyto stain

2.30

0.95

2.7

2.2

—

(3015736) pH of Urine

355

1.42

0.94

5.1

3.5

5.92

6.22

1.20

206

(3003327) Ova and parasites identified in Stool by Light microscopy

2.13

0.91

1.7

1.4

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

2.06

0.88

1.5

2.6

—

(3007164) IgA [Mass/volume] in Serum or Plasma

158

1.50

0.84

2.1

1.4

1.86

2.33

g/l

0.49

(3043409) Potassium [Moles/volume] in Arterial blood

0.00

0.80

0.0

3.1

—

4.01

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.80

0.0

1.3

—

0.83

—

(3019309) Folate [Moles/volume] in Red Blood Cells

151

1.49

0.79

2.8

1.6

1159.79

1203.24

nmol/l

0.09

119

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.90

0.75

1.1

1.3

—

(3022145) Colonoscopy Study observation

110

1.54

0.74

1.4

1.3

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.57

0.71

2.4

1.5

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

1.89

0.69

1.6

2.4

—

(3022948) Iron [Moles/volume] in Serum or Plasma

147

1.45

0.68

2.9

2.3

12.42

13.14

umol/l

0.13

135

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.64

0.68

1.2

1.7

—

(3021960) Folate [Moles/volume] in Serum or Plasma

249

1.35

0.65

1.9

1.7

19.64

20.70

nmol/l

0.10

204

(3004789) Transferrin [Mass/volume] in Serum or Plasma

140

1.44

0.64

2.8

2.2

2.36

2.29

g/l

0.20

128

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.65

0.63

1.3

1.7

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

1.70

0.62

2.0

1.6

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.61

0.0

2.5

—

18.57

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

0.00

0.61

0.0

1.3

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

0.00

0.61

0.0

1.4

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.59

0.0

1.3

—

1.59

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

341

1.29

0.55

1.8

2.1

1.30

1.29

mmol/l

0.01

274

(3000494) Fungus identified in Specimen by Culture

1.47

0.53

1.4

1.5

—

(42870588) Differential panel, method unspecified - Blood

285

1.29

0.52

6.1

5.1

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

511

1.27

0.51

6.1

4.5

7.25

6.71

mmol/l

1.04

487

(3020682) Albumin/Creatinine [Ratio] in Urine

293

0.76

0.50

5.9

3.9

6.69

6.35

mg/mmol

0.03

178

(3035350) Ketones [Presence] in Urine by Test strip

444

1.25

0.47

5.6

4.1

0.00

estimate

-0.00

106

(3012516) Albumin [Mass/volume] in Urine

280

0.77

0.46

3.6

3.3

20.88

35.27

mg/l

0.71

181

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

115

1.36

0.42

4.6

5.2

32.70

33.01

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.41

0.0

1.9

—

1.20

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.41

0.0

1.9

—

4.12

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.41

0.0

1.9

—

107.53

—

(3021601) Nitrite [Presence] in Urine by Test strip

441

1.22

0.39

5.6

4.0

0.00

estimate

-0.00

104

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

602

1.22

0.39

6.8

4.9

14.92

pmol/l

0.00

549

(3022313) Gas panel - Capillary blood

1.41

0.39

8.6

3.3

—

(3013707) Erythrocyte sedimentation rate [Velocity] in Red Blood Cells by Westergren method

615

1.21

0.35

6.1

4.7

12.67

12.52

mm/h

0.03

569

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

203

1.24

0.34

2.3

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

1.35

0.31

2.4

2.6

373.82

386.53

nmol/l

0.10

(3009261) Glucose [Presence] in Urine by Test strip

449

1.18

0.30

5.7

4.1

0.00

estimate

-0.00

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

149

1.25

0.30

1.3

44.29

7.59

u/ml

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

283

1.19

0.29

3.5

2.4

49.70

69.54

u/l

0.68

265

(3012095) Magnesium [Moles/volume] in Serum or Plasma

159

1.24

0.29

3.7

2.8

0.83

0.81

mmol/l

0.17

152

(3042936) Bacteria identified in Isolate by Culture

122

1.27

0.29

2.1

1.9

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

352

1.18

0.29

4.2

3.8

48.70

31.46

ng/l

0.46

253

(3009508) Creatinine [Moles/volume] in Urine

286

0.83

0.28

3.4

3.2

9.12

7.57

mmol/l

0.59

238

(3029937) Albumin [Presence] in Urine by Test strip

256

1.19

0.27

7.1

3.9

0.00

estimate

-0.00

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

1.27

0.26

6.8

3.8

1.21

1.23

mmol/l

—

(4035726) Immunohistochemistry procedure

1.27

0.26

1.4

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

727

1.18

0.25

7.6

5.8

1.69

1.92

mu/l

0.98

663

(3003458) Phosphate [Moles/volume] in Serum or Plasma

116

1.24

0.23

8.4

3.9

1.05

1.01

mmol/l

0.14

103

(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma

1.30

0.23

1.2

2.9

47.40

38.39

u/l

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

731

0.86

0.23

4.5

1.45

1.25

mmol/l

1.40

661

(3026008) Bacteria identified in Urine by Culture

280

1.15

0.22

5.3

3.2

—

(3025941) Bacteria identified in Stool by Culture

1.20

0.22

1.2

1.3

—

(40759850) Jo-1 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.5

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.5

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.21

0.0

1.0

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

0.00

0.21

0.0

1.0

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.21

0.0

1.1

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.4

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.21

0.0

1.2

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.21

0.0

1.1

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.21

0.0

1.1

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.21

0.0

2.1

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.21

0.0

1.0

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

0.21

0.0

1.0

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.20

0.0

1.4

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.20

0.0

1.4

—

(40760892) CBC W Ordered Manual Differential panel - Blood

194

0.85

0.18

4.9

5.0

—

(40761511) CBC panel - Blood by Automated count

794

0.87

0.17

22.2

14.6

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

0.75

0.17

1.4

1.3

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

130

1.18

0.17

1.5

1.4

—

(3000991) Gas panel - Venous blood

1.14

0.16

17.6

5.9

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.15

0.16

1.7

—

(3002032) Base excess in Venous blood by calculation

0.80

0.15

3.3

2.3

-1.19

2.60

mmol/l

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

396

1.10

0.14

2.8

2.7

—

estimate

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

0.81

0.14

1.4

1.8

—

(40768797) Stomach Pathology biopsy report

113

1.17

0.14

1.2

1.3

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

113

1.17

0.14

2.0

1.5

—

(3002256) Pathology report gross observation

104

1.17

0.13

1.2

1.3

—

(3003694) ABO and Rh group [Type] in Blood

219

0.89

0.12

1.8

1.5

—

(3014051) Protein [Presence] in Urine by Test strip

222

1.11

0.11

3.5

—

0.00

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

772

1.11

0.11

20.9

16.2

22.51

21.82

mg/l

0.07

659

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

768

0.91

0.11

5.4

5.5

4.76

4.63

mmol/l

0.54

710

(3019198) Lymphocytes [#/volume] in Blood

431

1.08

0.10

6.3

6.0

1.78

2.02

e9/l

0.73

383

(3013650) Neutrophils [#/volume] in Blood by Automated count

481

1.08

0.10

8.9

10.3

3.81

4.10

e9/l

0.40

424

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.12

0.10

1.0

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.07

0.09

1.0

1.8

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

754

1.09

0.09

8.1

6.9

39.97

40.21

mmol/mol

0.09

701

(3014007) Fractional oxyhemoglobin in Arterial blood

1.06

0.08

20.0

7.2

95.73

93.78

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

117

1.13

0.08

1.8

—

(3001604) Monocytes [#/volume] in Blood

423

1.07

0.08

6.4

5.9

0.53

0.58

e9/l

0.88

364

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

785

0.92

0.08

6.3

2.82

2.67

mmol/l

0.70

721

(4010399) Spirometry for bronchospasm with prolonged evaluation after bronchodilator

1.05

0.08

2.0

1.3

—

(3021589) Normoblasts [#/volume] in Blood

374

1.07

0.08

13.8

12.2

0.00

e9/l

0.50

307

(3014576) Chloride [Moles/volume] in Serum or Plasma

122

0.89

0.07

12.1

6.0

107.00

104.05

mmol/l

1.26

122

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

764

0.93

0.07

5.4

1.40

1.51

mmol/l

1.53

701

(3006315) Basophils [#/volume] in Blood

425

1.06

0.07

6.4

5.9

0.03

0.04

e9/l

0.79

365

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

455

0.94

0.07

3.0

2.7

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.12

0.06

1.5

1.6

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

100

0.89

0.06

6.4

7.7

—

(1761868) Lipid panel - Serum or Plasma

287

1.06

0.06

3.9

3.5

—

(3019150) Specific gravity of Urine by Refractometry

192

0.92

0.06

7.7

4.1

1.02

kg/l

0.15

129

(3013115) Eosinophils [#/volume] in Blood

437

1.05

0.05

6.2

6.4

0.19

e9/l

0.09

381

(40768804) Tissue Pathology biopsy report

322

0.95

0.05

2.4

2.2

—

(40758558) Short blood count panel - Blood

259

1.06

0.04

2.3

6.6

—

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

470

1.04

0.03

7.3

6.2

9.54

10.70

umol/l

0.51

446

(3041096) Erythrocytes [Presence] in Urine by Automated

262

1.04

0.02

5.0

3.5

0.00

estimate

-0.00

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

432

1.03

0.02

13.6

6.8

1.22

mmol/l

0.00

373

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

532

1.03

0.02

4.3

3.2

45.35

48.03

u/l

0.09

501

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

167

0.95

0.01

1.3

14.08

33.83

iu/ml

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

146

0.95

0.00

1.7

1.8

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

156

0.95

0.00

5.9

4.3

21.08

21.51

—

(3044640) Blood type and Crossmatch panel - Blood

286

0.97

0.00

2.5

2.2

—

(3023368) Bacteria identified in Blood by Culture

248

1.01

0.00

4.7

4.1

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

757

1.02

0.00

6.5

5.5

6.08

6.00

mmol/l

0.20

702

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

347

1.01

0.00

6.5

4.0

0.00

estimate

-0.00

(3020564) Creatinine [Moles/volume] in Serum or Plasma

824

0.97

0.00

26.5

21.3

82.95

75.39

umol/l

0.78

815

(3027946) Carbon dioxide [Partial pressure] in Arterial blood

106

1.04

0.00

12.3

6.3

5.12

5.27

kpa

0.24

101

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

104

0.96

0.00

1.3

1.7

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

0.0

1.0

—

(3032700) Glomerular basement membrane Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

0.0

1.0

—

(3012447) Hantavirus puumala IgG Ab [Titer] in Serum

0.00

0.0

1.1

—

(40760543) Extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.1

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.7

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

0.98

0.00

2.8

1.6

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.7

—

(3017817) Protein [Mass] in Urine collected for unspecified duration

0.00

0.0

1.8

—

809.88

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.7

—

(3018333) Ribosomal P Ab [Presence] in Serum

0.00

0.0

1.6

—

(3018301) Testosterone Free [Moles/volume] in Serum or Plasma

0.00

0.0

1.1

—

188.76

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.6

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.00

0.0

1.3

—

(3011648) Oxygen content in Venous blood

0.00

-0.00

0.0

2.6

—

10.57

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

-0.00

0.0

1.4

—

(3003245) Complement C1 esterase inhibitor [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

0.31

—

(42529528) Centromere protein B Ab [Units/volume] in Serum by Line blot

0.00

-0.00

0.0

1.3

—

(3037534) Parathyrin related protein [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.5

—

65.75

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

1.2

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

15.61

—

(3036432) Mycobacterium tuberculosis genotype [Identifier] in Isolate

0.00

-0.00

0.0

6.1

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

1.9

—

(3019420) Tryptase [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

5.73

—

(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

4.63

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

0.86

-0.00

23.6

7.0

0.92

1.45

—

(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(3044936) Clostridioides difficile toxin A+B [Presence] in Stool by Immunoassay

0.00

-0.00

0.0

1.0

—

(3016038) Potassium [Moles/volume] in Urine

0.00

-0.00

0.0

1.0

—

36.60

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

-0.00

0.0

1.4

—

(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

3.0

—

1206.00

—

(3013566) Clostridioides difficile [Presence] in Stool by Organism specific culture

0.00

-0.00

0.0

1.0

—

(37208534) Antinuclear antibody arbitrary concentration in serum

0.00

-0.00

0.0

1.0

—

(40760848) Basement membrane zone BP180 Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.2

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

0.97

-0.00

2.7

2.5

4.37

3.19

ratio

—

(3020911) Cortisol [Moles/time] in 24 hour Urine

0.00

-0.00

0.0

1.0

—

52.40

—

(40768441) Liver Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(40765096) Chromosome analysis panel by Banding

0.00

-0.00

0.0

1.0

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3035947) Staphylolysin Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

-0.00

0.0

1.2

—

(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum

0.00

-0.00

0.0

2.7

—

(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3015183) Erythrocyte sedimentation rate [Velocity] in Red Blood Cells

0.00

-0.00

0.0

1.0

—

11.80

—

(3025130) Human papilloma virus identified in Specimen

0.00

-0.00

0.0

2.7

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

20.0

—

825.50

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

0.87

-0.00

23.6

7.0

0.50

0.65

—

(4146454) Self-monitoring of blood glucose

0.00

-0.00

0.0

4.0

—

(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.4

—

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_URINARY_NOS and mortality.

Females

Parameter	HR [95% CI]	p-value
CD2_BENIGN_URINARY_NOS	2.076 [1.53, 2.81]	< 0.001
Birth year	0.992 [0.98, 1.0]	0.075

During the follow-up period (1.1.1998 — 31.12.2019), 107 out of 274 females with CD2_BENIGN_URINARY_NOS died.

Males

Parameter	HR [95% CI]	p-value
CD2_BENIGN_URINARY_NOS	1.753 [1.16, 2.64]	0.007
Birth year	0.989 [0.98, 1.0]	0.017

During the follow-up period (1.1.1998 — 31.12.2019), 88 out of 186 males with CD2_BENIGN_URINARY_NOS died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_URINARY_NOS.

N-year risk	Females	Males
1	0.158%	0.392%
5	1.142%	2.311%
10	2.997%	5.351%
15	5.58%	10.066%
20	9.505%	17.181%

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_URINARY_NOS – Benign neoplasm: Urinary organ, other/unspecified

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Benign neoplasm: Urinary organ, other/unspecified

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints