Cervical root disorders

G6_CERVROOT

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G54.2
  • Hospital discharge: ICD-9 3532
  • Cause of death: ICD-10 G54.2
  • Cause of death: ICD-9 3532

2 out of 7 registries used, show all original rules.

279

4. Check minimum number of events

None

279

5. Include endpoints

None

279

6. Filter based on genotype QC (FinnGen only)

252

Control definitions (FinnGen only)

Control exclude
G6_NERPLEX

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G54
Name in latin
Morbositates radicum nervorum cervicalium non alibi classificatae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1967 895 1060
Only index persons 1814 845 969
Unadjusted period prevalence (%)
Whole population 0.03 0.03 0.03
Only index persons 0.03 0.03 0.04
Median age at first event (years)
Whole population 53.07 52.51 53.45
Only index persons 52.39 51.91 52.81

-FinnGen-

Key figures

All Female Male
Number of individuals 252 128 124
Unadjusted period prevalence (%) 0.05 0.05 0.06
Median age at first event (years) 53.63 51.95 55.36

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
260
Matched controls
2600
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G54.2
ICD-10 Finland
Cervical root disorders, not elsewhere classified
+∞
284.4
218
*
XA402
NOMESCO Finland
ENMG
117.3
194.6
101
14
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
34.0
115.4
79
33
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
14.2
71.8
75
72
NAG40
NOMESCO Finland
Anterior fusion of cervical spine without fixation
26.5
66.4
48
22
G56.0
ICD-10 Finland
Carpal tunnel syndrome
17.3
59.6
53
38
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
12.4
50.5
55
55
N03AX16
ATC
[U] pregabalin
6.3
47.6
122
321
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
14.5
43.7
42
34
3532A
ICD-9 Finland
Nerve root and plexus disorders, Cervical root lesions, not elsewhere classified
+∞
42.9
40
*
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
5.9
42.0
105
266
M47.9
ICD-10 Finland
Spondylosis, unspecified
16.3
37.2
33
23
M54.2
ICD-10 Finland
Cervicalgia
6.8
34.1
62
114
M53.1
ICD-10 Finland
Cervicobrachial syndrome
6.0
33.5
73
160
G54.0
ICD-10 Finland
Brachial plexus disorders
51.9
30.5
36
8
N03AX12
ATC
[U] gabapentin; oral
4.9
28.2
78
208
G56.2
ICD-10 Finland
Lesion of ulnar nerve
100.1
25.2
27
*
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
4.6
25.1
74
206
ACC51
NOMESCO Finland
Release of median nerve
239.3
21.9
22
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.5
20.8
59
158
G55.1*M51.9
ICD-10 Finland
Nerve root and plexus compressions in intervertebral disc disorders (M50-M51+)
113.8
19.9
21
*
N02AX02
ATC
tramadol; systemic, rectal
3.2
18.9
152
793
N06AA09
ATC
amitriptyline; systemic
4.9
18.5
46
110
M54.4
ICD-10 Finland
Lumbago with sciatica
3.6
17.9
75
263
G55.1*M51.1
ICD-10 Finland
Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions
23.9
17.2
24
11
L01
ICPC
Neck symptom/complaint
3.7
17.0
66
220
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
96.4
16.8
18
*
K29
ICPC
Cardiovascular sympt/complt other
6.9
16.2
26
41
M48.0
ICD-10 Finland
Spinal stenosis
4.1
16.1
51
147
G55.2*M47.9
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
64.2
16.0
18
*
M50.3
ICD-10 Finland
Other cervical disc degeneration
18.7
15.9
24
14
N02BF01
ATC
gabapentin; oral
4.1
15.8
49
139
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.6
15.6
61
203
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
4.7
14.9
37
88
M54.1
ICD-10 Finland
Radiculopathy
6.2
14.0
25
44
Z01.9
ICD-10 Finland
Special examination, unspecified
4.8
13.8
33
76
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.6
12.8
144
841
N06AX21
ATC
duloxetine; oral
3.6
12.6
46
145
Z50.1
ICD-10 Finland
Other physical therapy
4.9
12.5
29
65
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
3.4
12.4
52
180
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
5.5
12.0
24
47
M54.5
ICD-10 Finland
Low back pain
2.5
11.6
115
625
M03BX02
ATC
tizanidine; oral
2.7
11.6
187
1273
ZYC05, ,
SPAT
10.8
11.2
21
21
N02AJ06
ATC
codeine and paracetamol; systemic
2.4
11.1
137
820
L28
ICPC
Limited function/disability (L)
2.8
11.0
65
273
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
3.5
10.8
40
127
A29
ICPC
General symptom/complaint other
3.0
10.5
52
198
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
3.9
10.0
31
87
M79.0
ICD-10 Finland
Rheumatism, unspecified
10.2
9.9
19
20
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
4.6
9.8
24
56
M54.8
ICD-10 Finland
Other dorsalgia
5.6
9.8
19
36
M01AX17
ATC
nimesulide; oral
2.5
9.6
77
374
WX408
NOMESCO Finland
General anesthesy, balanced
2.4
9.5
82
412
L03
ICPC
Low back symptom/complaint
2.4
9.4
87
451
A02BC02
ATC
pantoprazole; systemic
2.5
9.3
197
1444
XA420
NOMESCO Finland
Extensive sleep examination
14.4
9.3
15
11
M01AH05
ATC
etoricoxib; oral
2.4
9.1
185
1325
M25.5
ICD-10 Finland
Pain in joint
2.3
9.1
103
581
ABC30
NOMESCO Finland
Decompression of cervical nerve roots
38.1
9.1
11
*
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
3.7
9.1
30
88
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
11.3
8.9
16
15
ZYC01, ,
SPAT
3.1
8.9
40
143
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
8.1
8.8
19
25
M47.1
ICD-10 Finland
Other spondylosis with myelopathy
14.7
8.8
14
10
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.5
8.8
65
303
M19.0
ICD-10 Finland
Primary arthrosis of other joints
3.0
8.6
41
152
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.2
8.6
105
609
M79.6
ICD-10 Finland
Pain in limb
2.1
8.2
127
803
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
4.1
8.2
23
60
2402
FHL
External neurolysis of the nerve and possible alteration of the pathway (nerve pressure)
34.5
8.1
10
*
A02BC05
ATC
esomeprazole; systemic
2.1
8.1
118
730
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.2
7.8
83
451
Z01.8
ICD-10 Finland
Other specified special examinations
2.3
7.8
69
348
WX704
NOMESCO Finland
Intubation
3.6
7.8
27
82
N02BF02
ATC
pregabalin; oral
3.5
7.6
27
83
R51.80
ICD-10 Finland
Headache
2.6
7.5
51
227
G55.2
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
82.3
7.5
8
*
G54.4
ICD-10 Finland
Lumbosacral root disorders, not elsewhere classified
82.3
7.5
8
*
M89.0
ICD-10 Finland
Algoneurodystrophy
82.3
7.5
8
*
Z09.4
ICD-10 Finland
Follow-up examination after treatment of fracture
3.8
7.3
23
65
R1240
NOMESCO Finland
Social assessment of need and possibilities of rehabilitation
16.3
7.3
11
7
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.1
7.3
32
113
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.7
7.2
41
167
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.1
7.2
31
108
K30
ICD-10 Finland
Functional dyspepsia
2.8
7.2
40
161
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
7.3
7.1
16
23
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
6.9
86
495
XG405
NOMESCO Finland
Education on PEF monitoring
10.4
6.6
12
12
R43
ICPC
Respiratory, Other diagnostic procedure
10.4
6.6
12
12
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.5
6.6
23
70
M54.3
ICD-10 Finland
Sciatica
3.6
6.6
22
65
M79.7
ICD-10 Finland
Fibromyalgia
6.0
6.6
17
30
Z76.0
ICD-10 Finland
Issue of repeat prescription
2.1
6.5
85
496
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
14.8
6.4
10
7
M01AC06
ATC
meloxicam; systemic, rectal
2.0
6.4
106
674
Z00.6
ICD-10 Finland
Examination for normal comparison and control in clinical research programme
9.6
6.4
12
13
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.3
6.3
24
77
H02AB06
ATC
prednisolone; systemic
1.9
6.3
131
896
G51.0
ICD-10 Finland
Bell palsy
+∞
6.3
6
*
M77.1
ICD-10 Finland
Lateral epicondylitis
3.0
6.2
28
100
SGA01
NOMESCO Finland
Emergency treatment
2.3
6.2
50
240
R2110
NOMESCO Finland
Giving the first information
3.5
6.1
21
63
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
3.7
6.1
20
58
P03
ICPC
Feeling depressed
3.0
6.1
28
101
M65.3
ICD-10 Finland
Trigger finger
4.1
6.1
17
44
KMAK, ,
NOMESCO Finland
1.9
6.0
137
962

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
38
90
4.77
15.39
1.8
1.7
—
—
—
0
0
55
270
2.32
6.50
2.1
3.1
7.71
7.71
umol/l
0.00
47
241
108
693
1.96
6.30
8.6
6.8
—
—
—
0
0
44
210
2.32
5.51
2.0
2.1
0.00
0.07
estimate
—
5
45
83
511
1.92
5.31
3.0
3.8
1.02
1.02
kg/l
0.42
62
335
36
175
2.23
4.31
2.4
2.0
5.66
6.02
ph
2.18
31
114
66
406
1.84
4.12
1.4
1.3
30.39
30.28
iu/ml
0.00
29
125
122
900
1.67
3.98
3.0
3.5
0.00
0.03
estimate
0.78
15
193
60
366
1.83
3.83
1.3
1.3
33.20
11.54
u/ml
0.41
18
147
155
1224
1.66
3.83
5.4
7.1
0.19
0.19
e9/l
0.21
143
1059
64
952
0.57
3.82
2.8
3.2
—
—
—
0
0
119
886
1.63
3.66
2.9
3.6
24.69
100.25
ng/l
0.63
80
631
129
985
1.61
3.55
2.1
2.0
88.53
95.62
pmol/l
1.12
71
509
104
761
1.61
3.37
5.1
6.5
—
—
—
0
0
135
1054
1.58
3.31
11.3
11.8
1.14
1.22
inr
1.34
121
856
90
644
1.61
3.16
1.7
1.7
21.89
19.97
nmol/l
0.32
77
537
147
1180
1.57
3.13
3.4
3.6
0.00
0.00
estimate
-0.00
21
235
129
1015
1.54
2.94
2.2
2.8
—
—
estimate
—
0
0
9
22
4.20
2.91
1.2
1.2
—
—
—
0
0
147
1196
1.53
2.83
3.4
3.6
0.00
0.00
estimate
-0.00
22
241
129
1021
1.52
2.83
6.5
6.7
1.22
1.21
mmol/l
1.19
123
949
146
1188
1.52
2.80
5.5
6.7
0.57
0.58
e9/l
0.27
135
1007
195
1695
1.60
2.74
4.1
4.2
14.82
14.85
pmol/l
0.05
180
1545
146
1194
1.51
2.69
5.4
6.7
0.04
0.04
e9/l
0.49
134
1012
147
1207
1.50
2.64
5.5
6.7
1.93
1.92
e9/l
0.01
139
1052
158
1321
1.50
2.57
7.0
11.3
3.95
4.08
e9/l
0.28
148
1148
146
1202
1.49
2.56
3.3
3.6
0.00
0.04
estimate
1.06
19
227
210
1875
1.62
2.46
20.6
20.5
332.58
332.57
g/l
0.01
210
1870
75
544
1.53
2.40
2.5
3.6
—
0.33
—
0
6
62
433
1.57
2.34
3.5
3.7
130.10
285.20
ng/l
0.54
52
350
69
497
1.53
2.27
1.3
1.3
0.43
1.66
u/ml
2.05
15
153
21
109
2.01
2.17
1.0
1.1
—
—
—
0
0
118
954
1.43
2.15
2.5
3.3
5.94
6.17
ph
1.57
76
541
45
303
1.59
1.98
1.3
1.3
—
—
—
0
0
7
21
3.40
1.98
1.1
1.1
—
—
—
0
0
8
27
3.02
1.95
1.0
1.1
—
—
—
0
0
5
11
4.61
1.95
2.2
1.1
91.80
62.03
ng/l
—
5
11
73
552
1.45
1.87
2.0
2.0
1.93
2.87
mg/l
6.07
63
484
233
2172
1.70
1.86
17.6
15.8
20.08
25.84
mg/l
1.79
204
1781
5
12
4.23
1.83
1.0
1.4
—
—
—
0
0
132
1116
1.37
1.75
7.3
7.6
1.22
1.21
mmol/l
1.18
122
974
34
223
1.60
1.67
3.4
3.6
7.39
7.39
ph
0.05
28
114
239
2257
1.73
1.63
15.0
13.5
—
—
—
0
0
12
57
2.16
1.57
1.5
1.2
—
—
—
0
0
120
1015
1.34
1.52
2.7
2.4
80.23
76.65
nmol/l
0.66
115
916
14
73
1.97
1.47
1.2
1.4
—
—
—
0
0
12
59
2.08
1.46
1.5
1.2
—
—
—
0
0
12
59
2.08
1.46
1.5
1.2
—
—
—
0
0
13
236
0.53
1.46
1.7
1.5
—
—
—
0
0
86
696
1.35
1.45
3.5
4.4
7.40
7.40
ph
0.05
71
487
5
16
3.16
1.44
1.0
1.2
—
—
—
0
0
9
40
2.29
1.41
2.7
5.8
—
—
—
0
0
5
17
2.98
1.36
1.0
1.1
—
—
—
0
0
26
170
1.59
1.32
1.1
1.2
—
—
—
0
0
75
603
1.34
1.31
3.5
4.1
91.59
91.26
%
0.04
70
592
10
48
2.13
1.29
1.5
1.2
—
—
—
0
0
11
55
2.04
1.29
1.5
1.2
—
—
—
0
0
6
25
2.43
1.25
1.3
1.2
—
—
—
0
0
106
901
1.30
1.24
1.8
2.1
—
—
—
0
0
87
730
1.29
1.11
2.2
2.5
54.74
65.01
u/l
0.89
87
683
14
82
1.75
1.07
1.1
1.1
1.56
1.57
g/l
0.02
14
82
40
302
1.38
1.04
1.6
1.4
393.33
486.03
titre
0.37
12
73
15
91
1.69
1.03
1.3
1.4
—
18.56
—
0
5
0
29
0.00
0.98
0.0
1.5
—
—
—
0
0
7
36
1.97
0.98
1.1
1.4
—
72.54
—
0
5
0
31
0.00
0.97
0.0
1.1
—
—
—
0
0
14
85
1.68
0.96
1.1
1.2
0.86
0.95
g/l
0.62
14
85
216
2046
1.33
0.94
5.5
5.1
1.74
1.92
mu/l
1.52
206
1880
247
2394
1.63
0.93
25.3
23.9
4.54
4.51
e12/l
0.50
242
2350
34
257
1.37
0.89
6.2
9.5
1.17
0.75
mmol/l
0.36
28
225
32
415
0.74
0.84
4.5
2.8
525.00
533.99
mosm/kgh2o
0.09
27
360
61
508
1.26
0.82
1.6
1.8
1.95
1.37
mg/l
0.42
47
412
232
2232
1.37
0.80
5.3
5.3
4.52
4.68
mmol/l
1.87
222
2092
20
140
1.46
0.79
4.3
3.5
25.56
24.20
mmol/l
0.67
20
140
225
2157
1.32
0.78
5.5
5.2
6.10
5.98
mmol/l
0.72
217
2010
0
28
0.00
0.76
0.0
1.4
—
—
—
0
0
0
28
0.00
0.76
0.0
1.5
—
882.31
—
0
16
0
28
0.00
0.76
0.0
1.4
—
1.31
—
0
19
12
75
1.63
0.76
1.0
1.1
—
—
—
0
0
8
132
0.59
0.76
1.1
1.1
—
—
—
0
0
15
100
1.53
0.74
1.1
1.2
—
—
—
0
0
234
2259
1.36
0.74
6.1
6.0
2.64
2.74
mmol/l
1.03
225
2114
55
458
1.25
0.74
1.3
1.4
2.27
2.68
g/l
1.02
34
285
10
60
1.69
0.73
1.6
1.2
—
—
—
0
0
5
26
1.94
0.71
1.2
1.2
—
—
—
0
0
25
188
1.36
0.69
1.8
2.7
3.51
7.83
ug/l
1.97
19
170
33
262
1.30
0.65
6.2
9.4
7.41
7.42
ph
0.17
22
144
222
2138
1.26
0.63
4.2
4.4
1.30
1.29
mmol/l
0.12
211
1984
28
354
0.77
0.63
1.6
1.7
1185.29
1239.60
nmol/l
0.12
21
268
88
782
1.19
0.63
3.1
3.3
61.07
49.93
mg/l
0.09
52
493
74
650
1.19
0.60
3.5
2.9
0.00
0.01
estimate
0.50
15
180
0
22
0.00
0.59
0.0
1.0
—
292.46
—
0
13
15
207
0.71
0.59
1.1
1.4
—
—
—
0
0
0
23
0.00
0.58
0.0
15.6
—
966.83
—
0
23
0
23
0.00
0.58
0.0
2.9
—
42.51
—
0
13
6
37
1.64
0.56
1.7
1.3
—
—
—
0
0
6
38
1.59
0.54
3.0
2.9
—
—
—
0
0
18
134
1.37
0.54
1.2
1.2
240.05
122.36
u/ml
—
8
60
111
1018
1.16
0.53
4.0
4.8
36.57
35.97
g/l
0.59
104
960
7
46
1.54
0.48
6.1
1.2
—
—
—
0
0
89
808
1.15
0.48
3.2
3.2
8.05
7.89
mmol/l
0.12
79
677
5
82
0.60
0.46
7.2
8.9
—
—
—
0
0
29
239
1.24
0.45
2.1
1.5
—
—
—
0
0
228
2220
1.22
0.45
5.0
5.2
1.43
1.48
mmol/l
0.83
219
2072
9
126
0.70
0.44
1.4
1.3
—
—
—
0
0
87
794
1.14
0.44
3.6
3.8
2.27
8.24
mg/mmol
3.13
51
480
48
547
0.85
0.43
3.5
5.2
—
—
—
0
0
93
1008
0.88
0.42
2.0
2.0
1.27
1.35
mmol/l
0.69
83
851
39
335
1.19
0.41
2.4
1.9
—
—
—
0
0
17
132
1.31
0.41
1.2
2.6
—
—
—
0
0
0
15
0.00
0.41
0.0
2.2
—
11.98
—
0
15
0
17
0.00
0.41
0.0
1.0
—
36.08
—
0
17
26
312
0.81
0.40
1.2
1.3
—
—
—
0
0
32
271
1.21
0.39
1.3
1.4
—
—
—
0
0
58
642
0.88
0.36
2.8
3.1
0.21
0.40
e6/l
0.96
44
456
69
632
1.12
0.33
3.6
4.5
—
—
—
0
0
79
730
1.12
0.32
2.3
2.4
—
—
—
0
0
29
249
1.19
0.32
1.3
1.7
—
—
—
0
0
48
430
1.14
0.32
1.4
1.7
446.17
43611557.37
pmol/l
0.69
41
360
11
85
1.31
0.28
3.0
2.3
—
—
—
0
0
34
300
1.15
0.28
1.9
2.4
22.19
22.90
%
0.09
34
284
47
517
0.89
0.27
2.4
2.9
0.67
0.80
ug/l
0.77
32
326
13
159
0.81
0.25
3.0
3.1
—
—
—
0
0
84
789
1.10
0.25
3.0
3.6
2.36
2.36
mmol/l
0.09
77
721
20
170
1.19
0.25
1.3
1.4
—
—
—
0
0
217
2127
1.12
0.25
6.5
6.4
40.07
39.35
mmol/mol
0.63
208
2008
62
666
0.91
0.23
3.8
3.7
0.00
0.01
estimate
0.50
18
222
79
743
1.09
0.23
3.3
3.3
22.10
47.44
e6/l
1.25
63
563
5
39
1.29
0.23
1.0
1.7
—
—
—
0
0
5
39
1.29
0.23
1.0
1.7
—
—
—
0
0
5
39
1.29
0.23
1.0
1.7
—
—
—
0
0
5
39
1.29
0.23
1.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
0.29
—
0
5
0
12
0.00
0.21
0.0
1.5
—
7.37
—
0
7
42
385
1.11
0.20
3.1
3.0
2.20
2.19
e6/l
0.01
30
183
9
113
0.79
0.20
1.7
2.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
191.19
—
0
14
6
49
1.23
0.20
1.5
2.9
8.08
7.98
pmol/l
—
6
49
16
137
1.18
0.19
1.3
1.2
857.91
122.24
u/ml
0.75
16
127
36
329
1.11
0.19
2.0
2.3
2.37
2.32
g/l
0.27
36
304
110
1057
1.07
0.19
9.9
11.2
0.00
0.00
e9/l
0.52
99
844
11
132
0.83
0.18
3.0
2.6
1.18
1.22
%
0.08
11
132
11
132
0.83
0.18
3.0
2.6
0.68
0.61
%
0.26
11
132
7
60
1.17
0.18
1.6
1.4
—
—
—
0
0
23
205
1.13
0.17
5.0
5.8
0.00
0.22
%
—
6
51
26
234
1.12
0.17
1.4
1.5
—
—
—
0
0
29
263
1.12
0.17
2.3
4.8
2.57
53.27
ug/l
0.96
24
208
5
66
0.75
0.17
1.0
1.2
—
—
—
0
0
8
72
1.11
0.16
1.1
1.0
—
—
—
0
0
32
300
1.08
0.10
1.3
1.6
—
—
—
0
0
25
232
1.09
0.10
1.4
1.6
—
—
—
0
0
12
107
1.13
0.08
2.3
2.9
—
—
—
0
0
6
71
0.84
0.07
3.2
2.1
192.33
217.82
pmol/l
—
6
66
9
101
0.89
0.06
1.2
2.2
—
—
—
0
0
21
197
1.07
0.06
4.9
5.3
0.00
0.15
%
—
6
59
21
222
0.94
0.05
1.5
1.4
—
—
—
0
0
30
290
1.04
0.03
1.4
1.4
—
—
—
0
0
15
143
1.05
0.01
1.1
1.2
—
—
—
0
0
20
193
1.04
0.01
4.1
5.2
0.86
0.53
%
—
7
59
33
337
0.98
0.01
1.6
1.9
—
—
—
0
0
62
627
0.99
0.01
1.3
1.4
—
—
—
0
0
20
198
1.01
0.00
2.1
3.2
70.00
71.94
e9/l
0.12
15
143
24
238
1.01
0.00
1.8
2.3
32.79
30.69
u/l
0.15
19
196
63
632
1.00
0.00
3.6
2.9
—
—
—
0
0
20
197
1.02
0.00
7.8
10.6
—
—
—
0
0
86
855
1.01
0.00
4.1
3.9
133.63
121.61
e6/l
0.05
66
599
13
135
0.96
0.00
1.5
1.9
—
—
—
0
0
0
7
0.00
0.00
0.0
2.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.3
—
1795.63
—
0
8
0
6
0.00
-0.00
0.0
2.2
—
1.21
—
0
6
35
350
1.00
-0.00
5.5
7.9
105.00
104.11
mmol/l
0.71
35
350
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.3
—
2.63
—
0
8
5
49
1.02
-0.00
6.2
4.3
—
—
—
0
0
21
210
1.00
-0.00
4.9
5.2
0.67
0.86
%
—
6
72
7
78
0.89
-0.00
1.0
1.2
—
81.43
—
0
7
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
0.00
—
0
9
0
6
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.9
—
50.37
—
0
8
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint G6_CERVROOT and mortality.

Females

Parameter HR [95% CI] p-value
G6_CERVROOT 1.156 [0.87, 1.54] 0.324
Birth year 0.996 [0.99, 1.0] 0.362

During the follow-up period (1.1.1998 — 31.12.2019), 77 out of 666 females with G6_CERVROOT died.

Males

Parameter HR [95% CI] p-value
G6_CERVROOT 1.369 [1.08, 1.73] 0.009
Birth year 0.985 [0.97, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 117 out of 773 males with G6_CERVROOT died.

Mortality risk

Mortality risk for people of age

years, who have G6_CERVROOT.

N-year risk Females Males
1 0.088% 0.23%
5 0.607% 1.299%
10 1.623% 3.363%
15 3.355% 6.757%
20 5.694% 11.257%

Relationships between endpoints

Index endpoint: G6_CERVROOT – Cervical root disorders

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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