Cauda equina syndrome

G6_CAUDA

Cauda equina syndrome: Cauda equina syndrome refers to a group of symptoms that occur when some of the nerves in the cauda equina (the bundle of nerves that spread out from the bottom of the spinal cord) become compressed and/or damaged. Signs and symptoms of this condition include pain, numbness, or tingling in the lower back and/or legs; ' foot drop '; problems with bowel and/or bladder control; and sexual dysfunction. Cauda equina syndrome may be caused by a herniated disk , tumor , infection, fracture, or spinal stenosis . Treatment usually targets the underlying cause of the condition and often includes surgery to remove the material that is pressing on the nerves. Physical therapy , occupational therapy , and/or other services may be required if symptoms persist following surgery.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G83.4
  • Hospital discharge: ICD-9 3534B
  • Cause of death: ICD-10 G83.4
  • Cause of death: ICD-9 3534B

2 out of 7 registries used, show all original rules.

550

4. Check minimum number of events

None

550

5. Include endpoints

None

550

6. Filter based on genotype QC (FinnGen only)

490

Control definitions (FinnGen only)

Control exclude
G6_CPETAL

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G83
Name in latin
Syndroma caudae equinae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3048 1653 1377
Only index persons 2805 1572 1233
Unadjusted period prevalence (%)
Whole population 0.04 0.05 0.04
Only index persons 0.05 0.06 0.05
Median age at first event (years)
Whole population 54.69 54.54 54.67
Only index persons 53.39 53.76 52.91

-FinnGen-

Key figures

All Female Male
Number of individuals 490 305 185
Unadjusted period prevalence (%) 0.10 0.11 0.08
Median age at first event (years) 54.46 52.81 57.17

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
513
Matched controls
5130
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G83.4
ICD-10 Finland
Cauda equina syndrome
4503599627370496.0
307.7
501
*
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
13.3
201.6
301
495
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
13.9
198.1
251
331
ABC16
NOMESCO Finland
Microsurgical excision of lumbar intervertebral disc displacement
20.2
141.4
117
74
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
9.1
119.6
188
307
M54.4
ICD-10 Finland
Lumbago with sciatica
7.6
118.8
268
643
M48.0
ICD-10 Finland
Spinal stenosis
7.9
107.3
195
370
N03AX12
ATC
[U] gabapentin; oral
7.0
104.2
236
558
R33
ICD-10 Finland
Retention of urine
10.0
102.8
137
181
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
13.2
98.0
102
95
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
6.6
91.0
202
461
ABC26
NOMESCO Finland
Open discectomy of lumbar spine
22.0
90.0
69
36
N31.2
ICD-10 Finland
Flaccid neuropathic bladder, not elsewhere classified
42.1
86.9
53
14
N03AX16
ATC
[U] pregabalin
5.8
86.7
265
801
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
15.2
83.7
78
60
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
6.3
81.5
182
413
G55.1*M51.1
ICD-10 Finland
Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions
12.4
79.0
84
80
M54.5
ICD-10 Finland
Low back pain
5.3
73.4
340
1397
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
8.7
72.6
103
144
N02AX02
ATC
tramadol; systemic, rectal
5.3
69.0
366
1646
L86
ICPC
Back syndrome with radiating pain
7.5
68.4
112
184
ABC56
NOMESCO Finland
Decompression of lumbar spinal canal and nerve roots
14.2
67.0
64
51
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
6.9
65.4
116
207
M54.3
ICD-10 Finland
Sciatica
7.7
63.4
100
157
L03
ICPC
Low back symptom/complaint
4.4
60.1
273
1063
N02AA05
ATC
oxycodone; systemic
4.8
60.0
189
560
N06AX21
ATC
duloxetine; oral
5.2
59.4
154
389
ZXD35
NOMESCO Finland
Usual procedure
11.3
56.9
63
63
M54.9
ICD-10 Finland
Dorsalgia, unspecified
4.9
53.8
152
409
M54.1
ICD-10 Finland
Radiculopathy
8.1
52.3
76
108
ZXD05
NOMESCO Finland
Urgent procedure
4.0
52.1
260
1057
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
5.2
51.9
128
307
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
18.0
51.9
43
26
WX704
NOMESCO Finland
Intubation
5.6
47.4
102
216
R15
ICD-10 Finland
Faecal incontinence
10.3
45.3
53
57
WX408
NOMESCO Finland
General anesthesy, balanced
3.7
44.5
217
851
N02BF01
ATC
gabapentin; oral
4.5
42.1
123
335
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
15.1
42.0
38
27
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
4.0
40.7
151
489
XKC03
NOMESCO Finland
Water cystometry
8.6
40.3
54
69
N06AA09
ATC
amitriptyline; systemic
4.7
39.4
105
265
UKC02
NOMESCO Finland
Cystoscopy
4.1
39.1
134
409
G04CA02
ATC
tamsulosin; oral
3.7
37.9
163
580
A01
ICPC
Pain general/multiple sites
4.3
37.5
117
333
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
6.6
37.5
65
111
AA1AD
NOMESCO Finland
CT of head and brain
3.3
37.1
222
969
TPH04
NOMESCO Finland
Cathetrisation of vein
3.4
36.3
186
737
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
5.3
36.2
80
172
TKC22
NOMESCO Finland
Catheterisation instruction
10.5
36.1
41
42
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.7
35.5
146
502
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
8.4
35.5
48
62
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
5.5
34.4
72
147
XKD00
NOMESCO Finland
Uroflowmetry
4.0
34.2
116
349
L28
ICPC
Limited function/disability (L)
3.4
33.8
159
594
A06AD11
ATC
lactulose; oral
3.8
33.8
129
421
T36
ICD-10 Finland
Poisoning by systemic antibiotics
6.3
33.7
60
105
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
4.2
33.0
100
277
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
8.9
32.5
42
51
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.9
32.5
113
345
R52.2
ICD-10 Finland
Other chronic pain
6.1
32.4
60
109
TKC20
NOMESCO Finland
Catheterisation of bladder
5.1
31.7
73
162
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
7.8
30.6
44
61
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.7
30.1
114
368
N03AE01
ATC
clonazepam; systemic
5.1
29.9
68
149
N06AX16
ATC
venlafaxine; oral
3.4
29.8
135
489
J01MA02
ATC
ciprofloxacin; systemic
2.8
29.1
260
1373
WX725
NOMESCO Finland
Noninvasive ventilation
5.0
29.0
68
153
N02BF02
ATC
pregabalin; oral
4.4
28.0
77
197
U08
ICPC
Urinary retention
10.3
27.9
32
33
M47.9
ICD-10 Finland
Spondylosis, unspecified
7.1
27.6
43
65
R51.80
ICD-10 Finland
Headache
3.1
27.3
145
575
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
4.1
26.9
83
231
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.4
26.9
116
405
U07
ICPC
Urine symptom/complaint other
4.0
26.7
86
247
N03AX09
ATC
lamotrigine; oral
5.0
26.4
61
135
U05
ICPC
Urination problems other
5.0
26.2
61
136
ABD30
NOMESCO Finland
Implantation of spinal stimulation device
28.8
26.1
35
13
M03BX01
ATC
baclofen; systemic
9.0
26.0
33
39
N05AH04
ATC
quetiapine; oral
3.0
26.0
151
628
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.7
26.0
301
1779
Z01.8
ICD-10 Finland
Other specified special examinations
2.9
25.8
170
757
M79.6
ICD-10 Finland
Pain in limb
2.6
25.4
300
1783
N06AX11
ATC
mirtazapine; oral
2.6
25.1
241
1294
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
4.8
24.8
60
138
J01EA01
ATC
trimethoprim; systemic
2.7
24.4
186
888
NA1AD
NOMESCO Finland
Cervical spine CT examination
5.1
24.4
54
115
N30.0
ICD-10 Finland
Acute cystitis
3.0
24.1
137
560
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
6.2
24.1
43
75
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.6
24.0
295
1770
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
4.1
23.9
71
192
G82.2
ICD-10 Finland
Paraplegia, unspecified
251.2
23.8
24
*
WX402
NOMESCO Finland
General anaesthesia
2.8
23.8
166
757
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
4.6
23.7
60
143
M96.1
ICD-10 Finland
Postlaminectomy syndrome, not elsewhere classified
35.3
23.6
30
9
SPAT1229
SPAT
Assessment of need for aid
4.2
23.3
68
181
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
9.5
23.2
28
31
A28
ICPC
Limited function/disability NOS
3.0
23.0
129
522
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
3.2
22.8
108
397
R4110
NOMESCO Finland
Physiotherapy
2.6
22.7
193
967
N05CF01
ATC
zopiclone; oral
2.5
22.7
216
1142
N05AH03
ATC
olanzapine; systemic
4.0
22.6
69
190
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.6
22.4
195
987
JN3AD
NOMESCO Finland
Abdominal CT examination
3.1
22.4
110
413
X59
ICD-10 Finland
Exposure to unspecified factor
2.8
22.3
145
634
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
7.2
22.3
34
50
XKD06
NOMESCO Finland
Physiologic investigation of micturition
6.1
22.3
40
70
C03CA01
ATC
furosemide; systemic
2.6
22.1
186
925
N02AJ06
ATC
codeine and paracetamol; systemic
2.5
21.9
286
1739
N06AB04
ATC
citalopram; systemic
2.7
21.9
153
694
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
4.7
21.9
54
126
K59.09
ICD-10 Finland
Constipation, unspecified
4.1
21.8
64
171
ZXE20
NOMESCO Finland
More than three and less than five hours
3.1
21.8
106
395
S06.0
ICD-10 Finland
Concussion
3.3
21.5
95
334
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
5.2
21.5
46
95
N05AA02
ATC
levomepromazine; systemic
5.3
21.3
45
92
M51.9
ICD-10 Finland
Intervertebral disc disorder, unspecified
8.9
21.2
27
32
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.5
21.1
209
1118
UJF32
NOMESCO Finland
Coloscopy
2.6
21.0
174
856
G43.9
ICD-10 Finland
Migraine, unspecified
4.0
20.9
64
176
P03
ICPC
Feeling depressed
3.2
20.9
93
328
L17
ICPC
Foot/toe symptom/complaint
2.4
20.8
211
1139
M03BC01
ATC
orphenadrine (citrate); systemic
2.6
20.7
169
824
SPAT1254
SPAT
Administration of medicine
3.0
20.6
104
395
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
8.2
20.6
28
36
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
3.8
20.5
67
193
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
6.1
20.5
37
65
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.2
20.5
92
326
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.5
20.4
170
836
N03AF02
ATC
oxcarbazepine; oral
5.7
20.3
39
73
NA3DG
NOMESCO Finland
Lumbar spine very extensive MRI examination with high intensity magnet
37.4
20.0
25
7
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
6.2
19.9
35
60
M47.82
ICD-10 Finland
Other spondylosis, cervical region
4.8
19.6
46
103
A06AC01
ATC
ispaghula (psylla seeds); oral
2.5
19.4
180
927
R4120
NOMESCO Finland
Occupational therapy
3.9
19.4
62
176
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.7
19.3
67
201
M03BX02
ATC
tizanidine; oral
2.5
19.3
377
2679
TPH07
NOMESCO Finland
Cathetrisation of artery
3.2
19.3
86
303
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
3.4
19.3
75
243
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.0
19.1
100
387
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.2
18.9
83
290
N18
ICPC
Paralysis/weakness
8.0
18.8
26
34
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.7
18.6
63
186
Z3226
NOMESCO Finland
Physiotherapist
2.6
18.4
128
574
7227C
ICD-9 Finland
Intervertebral disk disorders, Intervertebral disk disorder with myelopathy[SYNDROMA ISCHIADICUM]
5.4
18.2
37
73
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
4.0
18.2
55
150
M54.8
ICD-10 Finland
Other dorsalgia
4.3
18.1
49
123
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.8
18.1
111
467
J01FF01
ATC
clindamycin; systemic
2.4
18.0
182
969
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.5
18.0
68
216
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
4.3
17.8
48
120
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.3
17.7
233
1383
G81.9
ICD-10 Finland
Hemiplegia, unspecified
186.2
17.6
18
*
SPAT1263
SPAT
Sampling
2.2
17.6
250
1530
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
6.5
17.4
29
47
ZXA05
NOMESCO Finland
Left side
2.4
17.2
153
767
R20.2
ICD-10 Finland
Paraesthesia of skin
3.5
17.2
64
201
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
32.7
17.2
22
7
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.8
17.1
101
415
AB5BT
NOMESCO Finland
Blockage of nerv root with X-ray guidance
20.1
17.0
25
13
TAB00
NOMESCO Finland
Lumbar puncture
4.2
16.9
47
120
G95.8
ICD-10 Finland
Other specified diseases of spinal cord
65.6
16.8
19
*
K59.0
ICD-10 Finland
Constipation
3.9
16.8
52
144
R07.4
ICD-10 Finland
Chest pain, unspecified
2.3
16.7
184
1010
R39.1
ICD-10 Finland
Other difficulties with micturition
5.4
16.7
34
67
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.7
16.7
109
472
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.3
16.7
177
957
ABD32
NOMESCO Finland
Implantation of temporary spinal stimulation device
20.9
16.6
24
12
N05AX12
ATC
aripiprazole; systemic
4.5
16.5
42
100
N05AF03
ATC
chlorprothixene; systemic
5.7
16.4
31
57
SPAT1167
SPAT
Insertion of urinary catheter
6.1
16.4
29
50
R06.0
ICD-10 Finland
Dyspnoea
2.3
16.3
177
965
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
17.4
16.2
25
15
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
3.3
16.2
65
214
P76
ICPC
Depressive disorder
3.3
16.2
65
214
N05BA04
ATC
oxazepam; oral
2.3
16.1
177
969
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
12.8
16.0
28
23
ZXE10
NOMESCO Finland
More than one and less than three hours
2.2
16.0
217
1291
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
3.5
16.0
58
179
NF3AA
NOMESCO Finland
Femur X-ray examination
6.6
16.0
26
41
X58
ICD-10 Finland
Exposure to other specified factors
2.6
15.9
110
489
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
4.9
15.9
36
78
ABC66
NOMESCO Finland
Decompression of lumbal spinal channel
62.0
15.9
18
*
S30.0
ICD-10 Finland
Contusion of lower back and pelvis
4.2
15.7
44
113
G55.1
ICD-10 Finland
Nerve root and plexus compressions in intervertebral disc disorders
14.3
15.7
26
19
A03
ICPC
Fever
2.5
15.7
118
546
N05CD07
ATC
temazepam; oral
2.9
15.6
83
322
N05AD01
ATC
haloperidol; systemic
6.1
15.4
27
46
SPAT1307
SPAT
Psychosocial counselling and guidance
3.9
15.3
47
129
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.9
15.1
76
286
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.4
15.1
136
682
U13
ICPC
Bladder symptom/complaint other
5.4
15.0
30
58
ZXA00
NOMESCO Finland
Right side
2.2
15.0
163
883
R60.9
ICD-10 Finland
Oedema, unspecified
3.8
15.0
48
136
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.0
15.0
71
258
F61.0
ICD-10 Finland
Mixed personality disorders
7.0
15.0
23
34
R32
ICD-10 Finland
Unspecified urinary incontinence
5.3
15.0
31
62
A04
ICPC
Weakness/tiredness general
2.5
14.9
110
503
A02BC02
ATC
pantoprazole; systemic
2.3
14.9
381
2866
SPAT1240
SPAT
Therapeutic discussion
2.9
14.9
80
312
N03AG01
ATC
valproic acid; systemic, rectal
3.5
14.8
54
167
U71
ICPC
Cystitis/urinary infection other
3.4
14.8
58
188
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.0
14.8
72
266
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.6
14.7
96
414
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.4
14.6
56
179
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
6.8
14.6
23
35
Z3231
NOMESCO Finland
Registered nurse
2.2
14.6
164
900
J01MA12
ATC
levofloxacin; systemic
2.4
14.6
117
556
W19
ICD-10 Finland
Unspecified fall
2.9
14.4
72
270
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.3
14.2
127
633
A46
ICD-10 Finland
Erysipelas
2.6
14.2
98
434
M01AB05
ATC
diclofenac; systemic, rectal
2.2
14.2
374
2818
R53
ICD-10 Finland
Malaise and fatigue
2.2
14.1
175
995
F29
ICD-10 Finland
Unspecified nonorganic psychosis
4.2
14.1
39
99
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.7
14.1
87
364
Z71.8
ICD-10 Finland
Other specified counselling
2.1
14.1
215
1324
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
13.2
14.0
24
19
NAG40
NOMESCO Finland
Anterior fusion of cervical spine without fixation
5.2
14.0
29
58
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
4.3
14.0
37
91
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.9
13.9
71
269
TKC10
NOMESCO Finland
Percutaneous puncture of bladder
20.7
13.9
20
10
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
6.5
13.9
23
37
M01AH05
ATC
etoricoxib; oral
2.1
13.8
360
2685
N30.9
ICD-10 Finland
Cystitis, unspecified
3.3
13.8
55
180
D11
ICPC
Diarrhoea
2.6
13.8
91
394
M01AH01
ATC
celecoxib; oral
2.4
13.7
116
563
A03FA01
ATC
metoclopramide; systemic, rectal
2.2
13.7
146
781
SPAT1262
SPAT
Handing over of treatment supplies
2.4
13.7
108
508
R42
ICD-10 Finland
Dizziness and giddiness
2.2
13.7
145
774
SPAT1153
SPAT
Removal of sutures
2.1
13.7
181
1054
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
3.2
13.6
57
192
C07AA05
ATC
propranolol; systemic
2.3
13.6
136
708
H02AB06
ATC
prednisolone; systemic
2.0
13.6
272
1838
WX702
NOMESCO Finland
Supraglottic ventilation device
3.4
13.6
52
166
N06AX03
ATC
mianserin; oral
3.8
13.5
43
121
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.0
13.5
243
1580
M54.2
ICD-10 Finland
Cervicalgia
2.9
13.5
71
273
R02
ICPC
Shortness of breath/dyspnoea
2.5
13.5
95
424
Z2446
NOMESCO Finland
Social worker
3.4
13.4
52
167
SPAT1215
SPAT
Assessment of need for medical rehabilitation
4.3
13.4
35
85
K07
ICPC
Swollen ankles/oedema
3.8
13.4
42
117
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.8
13.4
74
292
J01DB01
ATC
cefalexin; oral
2.7
13.4
449
3692
N05BA01
ATC
diazepam; systemic, rectal
2.5
13.3
93
413
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.9
13.1
68
259
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
9.7
13.1
26
28
SPAT1216
SPAT
Assessment of functional ability
2.5
13.1
96
436
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
4.8
13.0
30
66
RF210, ,
NOMESCO Finland
4.8
13.0
30
66
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.5
12.9
46
140
W17
ICD-10 Finland
Other fall from one level to another
4.4
12.9
33
79
U01
ICPC
Dysuria/painful urination
3.0
12.9
61
221
9211
FHL
Exploration or removal of diskusprolapse
5.5
12.9
25
47
S18
ICPC
Laceration/cut
2.0
12.8
271
1854
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.3
12.8
123
629
R55
ICD-10 Finland
Syncope and collapse
2.7
12.7
75
306
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.3
12.7
117
588
SPAT1255
SPAT
Intravenous administration of medicine
3.4
12.5
48
153
3534B
ICD-9 Finland
Nerve root and plexus disorders, Lumbosacral root lesions, not elsewhere classified[SYNDROMA CAUDAE EQUINAE]
+∞
12.5
12
*
D17
ICPC
Incontinence of bowel
13.6
12.5
21
16
F43.1
ICD-10 Finland
Post-traumatic stress disorder
4.9
12.5
28
60
P29
ICPC
Psychological sympt/compl other
2.9
12.4
62
232
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
3.9
12.3
37
100
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
5.3
12.3
25
49
L99
ICPC
Musculoskeletal disease other
5.3
12.3
25
49
N06AA10
ATC
nortriptyline; systemic
5.1
12.3
26
53
G44.2
ICD-10 Finland
Tension-type headache
2.4
12.3
98
462
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.6
12.3
76
318
S29
ICPC
Skin symptom/complaint other
2.2
12.2
132
706
M89.0
ICD-10 Finland
Algoneurodystrophy
12.8
12.2
21
17
M25.5
ICD-10 Finland
Pain in joint
2.0
12.2
209
1325
M51.8
ICD-10 Finland
Other specified intervertebral disc disorders
9.0
12.1
25
29
S21
ICPC
Skin texture symptom/complaint
2.3
12.1
102
492
R4110, ,
SPAT
2.4
12.1
90
411
Z50.1
ICD-10 Finland
Other physical therapy
3.4
12.1
44
136
B01AB05
ATC
enoxaparin; parenteral
2.0
12.0
183
1112
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.2
12.0
126
666
Z02.7
ICD-10 Finland
Issue of medical certificate
3.0
12.0
57
207
P01AB01
ATC
metronidazole; oral, rectal
1.9
11.8
238
1589
Z00.8
ICD-10 Finland
Other general examinations
2.8
11.8
64
250
R31
ICD-10 Finland
Unspecified haematuria
2.8
11.7
64
251
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.0
11.7
181
1104
A02BC01
ATC
omeprazole; systemic
2.0
11.7
161
943
R52.1
ICD-10 Finland
Chronic intractable pain
11.5
11.6
21
19
Z43.5
ICD-10 Finland
Attention to cystostomy
23.5
11.6
16
7
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.0
11.6
159
928
M70.6
ICD-10 Finland
Trochanteric bursitis
2.3
11.6
95
453
R10.0
ICD-10 Finland
Acute abdomen
4.8
11.5
26
56
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.2
11.5
47
156
SPAT1301
SPAT
No procedures
2.0
11.5
176
1069
N05AX08
ATC
risperidone; systemic
2.7
11.4
64
254
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
4.5
11.4
28
65
L12
ICPC
Hand/finger symptom/complaint
2.2
11.3
114
591
D06
ICPC
Abdominal pain localized other
2.7
11.3
64
255
J45.9
ICD-10 Finland
Asthma, unspecified
2.1
11.3
123
658
N06AX22
ATC
agomelatine; oral
4.9
11.3
25
53
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
5.7
11.3
21
38
L89
ICD-10 Finland
Decubitus ulcer and pressure area
5.7
11.3
21
38
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.7
11.3
64
256
R5110, ,
SPAT
2.7
11.2
63
250
N02AC04
ATC
dextropropoxyphene; oral
4.3
11.2
29
70
K10.3
ICD-10 Finland
Alveolitis of jaws
3.4
11.2
41
127
NAG63
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, more than 3 vertebraea
20.6
11.2
16
8
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
5.4
11.2
22
42
T74.1
ICD-10 Finland
Physical abuse
5.4
11.2
22
42
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.5
11.1
79
352
M79.0
ICD-10 Finland
Rheumatism, unspecified
4.3
11.0
29
71
M01AE03
ATC
ketoprofen; systemic, rectal
1.9
11.0
205
1326
S93.4
ICD-10 Finland
Sprain and strain of ankle
2.5
11.0
78
348
R96
ICPC
Asthma
2.6
11.0
71
303
N81
ICPC
Injury nervous system other
44.3
11.0
13
*
WX720
NOMESCO Finland
Own respiration
3.3
11.0
42
134
N07BC02
ATC
methadone; systemic
15.9
10.9
17
11
N02BE01
ATC
paracetamol; systemic, rectal
3.1
10.9
477
4146
K59.00
ICD-10 Finland
Constipation caused by slow bowel passage (SCT)
5.1
10.8
23
47
L02
ICPC
Back symptom/complaint
2.4
10.8
78
350
S22.0
ICD-10 Finland
Fracture of thoracic vertebra
5.7
10.8
20
36
R56.8
ICD-10 Finland
Other and unspecified convulsions
3.6
10.8
36
105
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.9
10.7
53
197
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
4.8
10.6
24
52
R50.9
ICD-10 Finland
Fever, unspecified
2.3
10.5
95
470
A02BA02
ATC
ranitidine; systemic
2.1
10.5
115
615
PA6AD
NOMESCO Finland
CT of neck arteries
3.7
10.5
34
97
N06AB10
ATC
escitalopram; oral
2.0
10.5
132
744
N39.9
ICD-10 Finland
Disorder of urinary system, unspecified
5.6
10.5
20
37
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
5.6
10.5
20
37
J01CA08
ATC
pivmecillinam; oral
1.9
10.4
235
1607
S70.0
ICD-10 Finland
Contusion of hip
3.8
10.4
32
88
L84
ICPC
Back syndrome without radiat pain
3.2
10.4
43
144
N06AB05
ATC
paroxetine; oral
3.1
10.4
45
155
P01
ICPC
Feeling anxious/nervous/tense
2.3
10.3
86
412
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.5
10.2
69
300
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
3.9
10.2
30
80
ZYC01
NOMESCO Finland
Remote contact by phone
2.9
10.2
49
179
F60.9
ICD-10 Finland
Personality disorder, unspecified
8.7
10.1
21
25
H01
ICPC
Ear pain/earache
2.3
10.1
80
374
A02BC05
ATC
esomeprazole; systemic
1.8
10.1
227
1547
S80.0
ICD-10 Finland
Contusion of knee
2.7
10.1
58
233
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.8
10.1
54
209
M54
ICD-10 Finland
Dorsalgia
2.3
10.0
82
389
NF1AA
NOMESCO Finland
Hip X-ray examination
2.7
10.0
58
234
N06AX12
ATC
bupropion; oral
2.7
10.0
56
222
R60.0
ICD-10 Finland
Localized oedema
2.3
10.0
81
383
T78.4
ICD-10 Finland
Allergy, unspecified
3.6
9.9
33
96
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
3.4
9.9
36
111
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
3.9
9.9
29
77
S01
ICPC
Pain/tenderness of skin
3.5
9.9
35
106
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
4.5
9.9
24
55
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.9
9.9
49
182
R13
ICD-10 Finland
Dysphagia
2.8
9.8
51
194
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.3
9.8
38
122
J01AA02
ATC
doxycycline; systemic
2.1
9.8
410
3382
N07BB01
ATC
disulfiram; oral
3.4
9.8
35
107
N06AX26
ATC
vortioxetine; oral
2.7
9.7
54
213
C07AB07
ATC
bisoprolol; oral
1.8
9.7
253
1798
G83.9
ICD-10 Finland
Paralytic syndrome, unspecified
56.1
9.7
11
*
M03BC51
ATC
orphenadrine, combinations; systemic
1.9
9.6
163
1013
WX400
NOMESCO Finland
Inhalation anesthesy
3.4
9.6
35
108
NA2AD
NOMESCO Finland
Thoracic spine CT examination
15.4
9.6
15
10
R06.4
ICD-10 Finland
Hyperventilation
7.8
9.5
21
28
L29
ICPC
Musculoskeletal sympt/complt other
2.5
9.5
61
259
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.9
9.5
162
1009
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.6
9.5
32
94
TKC20, ,
SPAT
17.9
9.4
14
8
OAB50, ,
SPAT
2.6
9.4
56
229
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.8
9.4
254
1818
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
3.8
9.4
29
80
J46
ICD-10 Finland
Status asthmaticus
4.6
9.4
22
49
F99
ICD-10 Finland
Mental disorder, not otherwise specified
4.8
9.4
21
45
R06AE07
ATC
cetirizine; oral
1.8
9.4
242
1709
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
3.1
9.4
39
131
ZY010
NOMESCO Finland
Hospital outpatient
3.1
9.4
39
131
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.0
9.4
43
153
G55.1*M51.9
ICD-10 Finland
Nerve root and plexus compressions in intervertebral disc disorders (M50-M51+)
8.9
9.4
19
22
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
3.3
9.4
35
110
A02BC03
ATC
lansoprazole; oral
1.9
9.3
162
1013
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
3.1
9.3
40
137
K04.08
ICD-10 Finland
Other specified pulpit
2.6
9.2
56
231
N06AB06
ATC
sertraline; oral
2.3
9.2
76
361
SPAT1211
SPAT
Application of soft bandage
2.6
9.2
56
232
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
4.9
9.1
20
42
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.4
9.1
67
303
NA7BT
NOMESCO Finland
Injection to spinal facet joint with radiological guidance
15.9
9.1
14
9
NAW00
NOMESCO Finland
Repair of wound dehiscence in surgery of spine or neck
37.4
9.0
11
*
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
3.5
9.0
31
92
P15
ICPC
Chronic alcohol abuse
4.1
9.0
25
64
G99.2*M51.0
ICD-10 Finland
Lumbar and other intervertebral disc disorders with myelopathy
24.5
8.9
12
5
AEA24
NOMESCO Finland
Removal of spinal stimulation elecrode
24.5
8.9
12
5
D01
ICPC
Abdominal pain/cramps general
2.2
8.9
81
401
F39
ICD-10 Finland
Unspecified mood [affective] disorder
5.0
8.9
19
39
M43.1
ICD-10 Finland
Spondylolisthesis
3.3
8.8
34
109
H02AB07
ATC
prednisone; oral
2.2
8.8
81
403
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.8
8.8
297
2251
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.7
8.8
28
79
R07.3
ICD-10 Finland
Other chest pain
2.3
8.7
68
315
M54.0
ICD-10 Finland
Panniculitis affecting regions of neck and back
6.8
8.7
21
32
N30.8
ICD-10 Finland
Other cystitis
14.3
8.7
14
10
A29
ICPC
General symptom/complaint other
2.1
8.7
87
447
T91.3
ICD-10 Finland
Sequelae of injury of spinal cord
50.9
8.7
10
*
XKD03
NOMESCO Finland
Urethral pressure profilometry
4.5
8.7
21
48
R11
ICD-10 Finland
Nausea and vomiting
2.4
8.7
61
270
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
4.9
8.7
19
40
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.2
8.7
75
364
M16.1
ICD-10 Finland
Other primary coxarthrosis
2.3
8.6
71
337
ZXE00
NOMESCO Finland
One hour or less
1.8
8.6
208
1431
R52.9
ICD-10 Finland
Pain, unspecified
2.3
8.6
71
338
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.8
8.6
26
71
B80
ICPC
Iron deficiency anaemia
4.3
8.5
22
53
R05
ICPC
Cough
1.9
8.5
144
890
A50
ICPC
General and Unspecified, Medication/prescr/renewal
3.4
8.5
31
96
WX290
NOMESCO Finland
Other blockage of nerve
1.7
8.5
263
1939
N06AB03
ATC
fluoxetine; oral
2.2
8.5
79
395
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.8
8.5
43
162
SPAT1252
SPAT
Overall medication plan or its review
2.8
8.5
43
162
P16
ICPC
Acute alcohol abuse
5.0
8.4
18
37
G56.4
ICD-10 Finland
Causalgia
13.0
8.4
14
11
F10.09
ICD-10 Finland
Alcohol intoxication UNS
4.8
8.4
19
41
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
8.4
137
837
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
3.6
8.4
27
77
C01CA24
ATC
epinephrine; parenteral
2.7
8.3
46
181
R03BB04
ATC
tiotropium bromide; inhalant
2.5
8.3
56
243
N01
ICPC
Headache
2.2
8.3
77
384
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.8
8.3
150
946
K92.1
ICD-10 Finland
Melaena
3.1
8.2
35
119
E66.8
ICD-10 Finland
Other obesity
2.9
8.2
40
147
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
8.2
182
1219
XF600
NOMESCO Finland
Bloodpressure measurement
2.8
8.1
40
148
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
3.1
8.1
34
115
WX002
NOMESCO Finland
Sedation and analgesia
2.0
8.1
108
617
M79.7
ICD-10 Finland
Fibromyalgia
3.5
8.0
28
84
M54.6
ICD-10 Finland
Pain in thoracic spine
2.5
8.0
53
228
N17
ICPC
Vertigo/dizziness
2.1
8.0
78
397
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.3
8.0
60
274
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
3.7
7.9
25
70
WX110
NOMESCO Finland
Infiltration anesthesia
1.8
7.9
376
3095
ND1AA
NOMESCO Finland
Wrist X-ray examination
2.6
7.9
47
192
R03AC02
ATC
salbutamol; inhalant
1.7
7.9
299
2311
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.2
7.9
32
106
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.1
7.9
82
428
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
3.0
7.9
34
117
AEA00
NOMESCO Finland
Replacement of impulse generator of stimulation device in the nervous system
9.6
7.8
15
16
SPAT1234
SPAT
Support of social functional capacity
3.1
7.8
33
112
N02AJ13
ATC
tramadol and paracetamol; systemic
4.3
7.8
20
48
N06AA06
ATC
trimipramine; systemic
4.0
7.8
22
57
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
3.6
7.8
26
76
N05BE01
ATC
buspirone; oral
3.5
7.8
27
81
F31.31
ICD-10 Finland
Bipolar disorder depressive episode with somatic syndrome
15.3
7.7
12
8
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
4.4
7.7
19
44
AEA20
NOMESCO Finland
Removal of impulse generator of stimulation device in the nervous system
45.7
7.7
9
*
L05
ICPC
Flank/axilla symptom/complaint
2.6
7.7
44
176
XF400
NOMESCO Finland
ECG with 12 standard connections
2.1
7.7
83
438
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.8
7.7
23
62
R09.1
ICD-10 Finland
Pleurisy
4.6
7.7
18
40
N07BA03
ATC
varenicline; oral
3.0
7.7
35
124
EBA00
NOMESCO Finland
Extraction of tooth
1.7
7.7
193
1333
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
3.7
7.7
24
67
G04BD08
ATC
solifenacin; oral
2.6
7.6
45
183
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
3.3
7.6
28
87
M13.9
ICD-10 Finland
Arthritis, unspecified
2.5
7.6
49
208
K08.3
ICD-10 Finland
Retained dental root
2.6
7.6
46
190
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.8
7.6
145
927
G44.8
ICD-10 Finland
Other specified headache syndromes
7.3
7.5
17
24
L02.3
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of buttock
4.3
7.5
19
45
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.8
7.5
37
137
N05CF02
ATC
zolpidem; oral
1.9
7.5
101
578
KH1AT
NOMESCO Finland
Urinary tract cathetrisation with ultrasound guidance
81.2
7.4
8
*
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
3.0
7.4
32
110
N06AX05
ATC
trazodone; oral
3.7
7.4
23
64
U04
ICPC
Incontinence urine
2.7
7.4
40
156
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
3.3
7.4
27
84
L15
ICPC
Knee symptom/complaint
1.8
7.3
143
917
ZZH31
NOMESCO Finland
Bone allograft, small pieces
11.1
7.3
13
12
SPAT1243
SPAT
Psychiatric/psychological examination
3.9
7.3
21
55
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.8
7.3
127
787
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.0
7.3
89
491
AWB00
NOMESCO Finland
Reoperation for superficial infection in surgery of the nervous system
+∞
7.3
7
*
M51.0
ICD-10 Finland
Lumbar and other intervertebral disc disorders with myelopathy
+∞
7.3
7
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.5
7.3
48
206
B01AB04
ATC
dalteparin; parenteral
3.0
7.3
32
111
M96.0
ICD-10 Finland
Pseudarthrosis after fusion or arthrodesis
16.0
7.3
11
7
NAU20
NOMESCO Finland
Removal of internal fixation device from spine or neck
16.0
7.3
11
7
N04BC05
ATC
pramipexole; oral
2.4
7.3
49
213
A11
ICPC
Chest pain NOS
2.3
7.2
55
252
S33.5
ICD-10 Finland
Sprain and strain of lumbar spine
7.5
7.2
16
22
G55.2*M47.9
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
4.6
7.2
17
38
M80.0
ICD-10 Finland
Postmenopausal osteoporosis with pathological fracture
4.6
7.2
17
38
A41.8
ICD-10 Finland
Other specified sepsis
4.6
7.2
17
38
S83.6
ICD-10 Finland
Sprain and strain of other and unspecified parts of knee
2.7
7.2
38
146
NAJ32
NOMESCO Finland
Posterior reduction of fractrue of lumbar spine
30.5
7.2
9
*
Z72.2
ICD-10 Finland
Drug use
20.4
7.2
10
5
F34.1
ICD-10 Finland
Dysthymia
2.9
7.1
33
118
G56.2
ICD-10 Finland
Lesion of ulnar nerve
3.2
7.1
28
91
G04BD12
ATC
mirabegron; oral
2.1
7.1
72
371
J01FA06
ATC
roxithromycin; oral
1.7
7.1
211
1516
M05BX04
ATC
denosumab; parenteral
2.6
7.1
40
159
M51.2
ICD-10 Finland
Other specified intervertebral disc displacement
12.3
7.1
12
10
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.2
7.1
60
288
S97
ICPC
Chronic ulcer skin
2.5
7.1
44
184
F33.4
ICD-10 Finland
Recurrent depressive disorder, currently in remission
3.6
7.1
23
66
H53.2
ICD-10 Finland
Diplopia
3.3
7.1
26
81
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.7
7.1
204
1455
TAB20
NOMESCO Finland
Epidural puncture
10.2
7.1
13
13
NA3SA
NOMESCO Finland
Lumbar spine X-ray examination in standing position
10.2
7.1
13
13
L03.9
ICD-10 Finland
Cellulitis, unspecified
4.3
7.1
18
43
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
2.2
7.1
63
309
ZZA00
NOMESCO Finland
Split skin graft
4.0
7.0
20
52
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
2.6
7.0
42
172
K04.4
ICD-10 Finland
Acute apical periodontitis of pulpal origin
2.2
7.0
61
296
R52.0
ICD-10 Finland
Acute pain
3.2
7.0
28
92
RF220, ,
NOMESCO Finland
6.5
7.0
17
27
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
6.5
7.0
17
27
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.8
7.0
35
131
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
2.6
7.0
41
167
K59.1
ICD-10 Finland
Functional diarrhoea
2.6
7.0
41
167
Z72.0
ICD-10 Finland
Tobacco use
4.1
6.9
19
48
M79.1
ICD-10 Finland
Myalgia
1.9
6.9
95
545
R25.1
ICD-10 Finland
Tremor, unspecified
3.7
6.9
22
62
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
2.9
6.9
33
120
P19
ICPC
Drug abuse
14.0
6.9
11
8
P80
ICPC
Personality disorder
14.0
6.9
11
8
P06
ICPC
Sleep disturbance
2.0
6.9
82
448
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.8
6.9
35
132
D12
ICPC
Constipation
3.1
6.9
28
93
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
3.9
6.9
20
53
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
4.2
6.9
18
44
NH1AD
NOMESCO Finland
Ankle and foot CT
4.2
6.9
18
44
M47.1
ICD-10 Finland
Other spondylosis with myelopathy
6.8
6.9
16
24
S63.5
ICD-10 Finland
Sprain and strain of wrist
3.0
6.9
30
104
Z2221
NOMESCO Finland
Medical doctor
1.7
6.9
145
950
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.8
6.8
108
649
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.2
6.8
57
272
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.2
6.8
57
272
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.5
6.8
43
181
XA402
NOMESCO Finland
ENMG
3.7
6.8
21
58
N03AX11
ATC
topiramate; oral
3.6
6.8
22
63
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
2.2
6.7
59
287
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.2
6.7
61
301
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
3.2
6.7
26
84
XG410
NOMESCO Finland
Flow-volume spirometry
3.2
6.7
26
84
M01AH02
ATC
rofecoxib; oral
2.0
6.7
72
380
J02AC01
ATC
fluconazole; systemic
1.6
6.6
211
1536
B01AA03
ATC
warfarin; systemic
1.9
6.6
86
485
R51
ICD-10 Finland
Headache
2.6
6.6
37
147
X57
ICD-10 Finland
Unspecified privation
3.9
6.6
19
50
J01DA01
ATC
[U] cefalexin
1.6
6.6
317
2553
U02
ICPC
Urinary frequency/urgency
1.9
6.5
87
494
SPAT1284
SPAT
Extensive health certificate
3.7
6.5
20
55
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.7
6.5
151
1012
M01AC06
ATC
meloxicam; systemic, rectal
1.6
6.5
195
1397
C08CA05
ATC
nifedipine; systemic
2.7
6.5
35
136
IGY02, ,
SPAT
6.3
6.5
16
26
KH1AD
NOMESCO Finland
CT of urinary organs
3.3
6.5
24
75
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.8
6.5
126
804
I50.9
ICD-10 Finland
Heart failure, unspecified
2.0
6.5
69
362
R5599
NOMESCO Finland
Other rehabilitation service
3.5
6.5
22
65
C01DA14
ATC
isosorbide mononitrate; oral
2.0
6.5
75
406
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.8
6.5
100
596
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.5
6.5
40
167
Z00.0
ICD-10 Finland
General medical examination
1.8
6.4
107
652
AEA27
NOMESCO Finland
Replacement of spinal stimulation electrode
70.7
6.4
7
*
F44.4
ICD-10 Finland
Dissociative motor disorders
70.7
6.4
7
*
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
2.1
6.4
60
300
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.0
6.4
76
415
WX882
NOMESCO Finland
High dependency care
4.2
6.4
17
42
R35
ICD-10 Finland
Polyuria
2.4
6.4
44
193
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.2
6.4
56
273
T82
ICPC
Obesity
2.9
6.4
29
103
XA800
NOMESCO Finland
Neuropsychological investigation
2.9
6.4
29
103
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
8.3
6.4
13
16
N31.1
ICD-10 Finland
Reflex neuropathic bladder, not elsewhere classified
11.2
6.3
11
10
SPAT1285
SPAT
Provision of consultation response
2.8
6.3
31
115
ABD99
NOMESCO Finland
Other operation on spinal cord or nerve for pain or impaired function
18.3
6.3
9
5
N05AE05
ATC
lurasidone; oral
18.3
6.3
9
5
P99
ICPC
Psychological disorders other
3.2
6.3
25
82
D07BC01
ATC
betamethasone and antiseptics; topical
2.0
6.3
66
345
NA3CD
NOMESCO Finland
Very extensive lumbar spien and sacrum CT-examination
+∞
6.3
6
*
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
3.0
6.3
27
93
QCB10
NOMESCO Finland
Major dressing of wound of skin of upper limb
3.8
6.3
19
52
J01FA09
ATC
clarithromycin; systemic
1.7
6.2
165
1143
N76.0
ICD-10 Finland
Acute vaginitis
2.4
6.2
41
176
ZXF00
NOMESCO Finland
Interruption caused by intraoperative deterioration of general condition
27.0
6.2
8
*
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.7
6.2
144
963
IHZ05, ,
SPAT
2.8
6.2
30
110
R1250
NOMESCO Finland
Evaluation of functional capability
3.6
6.2
20
57
T88.7
ICD-10 Finland
Unspecified adverse effect of drug or medicament
4.1
6.2
17
43
F41.09
ICD-10 Finland
UNS Panic Syndrome
3.4
6.2
22
67
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
6.4
6.2
15
24
P27
ICPC
Fear of mental disorder
6.4
6.2
15
24
ZXD20
NOMESCO Finland
Day surgery
2.0
6.2
72
390
WZC00, ,
SPAT
1.9
6.2
81
457
SPAT1231
SPAT
Assessment of adjustments needed in living environment
5.9
6.2
16
28
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.4
6.2
44
196
WX872
NOMESCO Finland
Intensive care
2.7
6.2
32
122
A97
ICPC
No disease
1.8
6.2
113
708
M01AE02
ATC
naproxen; oral, rectal
1.6
6.2
296
2365
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.8
6.1
112
701
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.8
6.1
112
701
P25
ICPC
Phase of life problem adult
3.0
6.1
27
94
N93.9
ICD-10 Finland
Abnormal uterine and vaginal bleeding, unspecified
3.9
6.1
18
48
63497
ICD-8 Finland
Other complications of pregnancy, Partus prematurus imminens, alibi non classificabilis
4.2
6.1
16
39
G43.8
ICD-10 Finland
Other migraine
4.2
6.1
16
39
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.8
6.1
31
117
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
2.8
6.1
31
117
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
2.7
6.1
32
123
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
3.7
6.1
19
53
WVA20, ,
SPAT
3.0
6.1
26
89
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.9
6.1
77
430
L03.0
ICD-10 Finland
Cellulitis of finger and toe
2.2
6.1
52
251
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
3.4
6.1
21
63
M50.9
ICD-10 Finland
Cervical disc disorder, unspecified
10.2
6.1
11
11
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.1
6.0
25
84
B01AF02
ATC
apixaban; oral
2.0
6.0
65
343
JN4AD
NOMESCO Finland
Body CT examination
2.0
6.0
65
343
H53.1
ICD-10 Finland
Subjective visual disturbances
2.3
6.0
45
205

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
296
1340
3.86
50.00
6.1
3.1
—
—
—
0
0
256
1193
3.29
38.60
6.4
4.3
—
—
—
0
0
362
2230
3.12
30.87
9.2
7.3
1.21
1.21
mmol/l
1.43
333
1946
338
2016
2.98
30.37
8.4
6.5
1.20
1.21
mmol/l
3.39
326
1870
327
1931
2.91
29.67
7.5
5.0
34.99
36.04
g/l
2.76
312
1809
348
2141
2.94
28.91
4.1
2.7
—
—
estimate
—
0
0
86
235
4.20
28.68
11.1
12.4
16.59
15.64
%
2.34
81
225
134
494
3.32
28.64
10.0
9.4
7.40
7.42
ph
1.49
77
281
260
1386
2.78
28.35
3.3
2.1
138.63
223.24
u/l
1.12
251
1324
133
493
3.29
28.12
10.0
9.4
1.98
1.01
mmol/l
2.67
111
413
133
499
3.25
27.51
9.7
9.2
12.54
12.13
kpa
0.38
128
482
133
499
3.25
27.51
9.7
9.3
5.29
5.13
kpa
1.06
128
482
368
2392
2.91
26.46
8.3
6.7
8.93
11.13
umol/l
8.47
361
2283
168
736
2.91
26.33
3.2
3.2
0.81
0.82
mmol/l
0.49
161
698
262
1444
2.66
26.13
4.5
2.6
50.58
63.92
u/l
2.11
247
1350
417
2926
3.27
25.57
10.6
4.6
1080.13
1357.74
e6/l
—
8
47
182
854
2.75
24.81
6.3
3.9
62.01
324.87
ng/l
2.23
121
651
326
2039
2.64
24.47
13.7
12.2
1.16
1.21
inr
0.91
260
1689
133
537
2.99
23.92
2.3
1.7
—
—
—
0
0
383
2625
2.81
23.35
9.6
5.2
6.42
6.63
mmol/l
1.37
371
2487
152
671
2.80
23.08
2.9
2.2
—
—
—
0
0
246
1396
2.46
21.99
4.0
4.0
7.40
7.40
ph
0.58
189
988
256
1480
2.46
21.95
3.5
2.3
—
—
—
0
0
249
1447
2.40
20.79
6.3
3.2
254.06
56.62
e6/l
0.43
210
1093
254
1500
2.37
20.30
7.2
6.0
—
—
—
0
0
190
990
2.46
20.11
4.4
2.7
5.30
6.38
e6/l
0.47
177
905
51
123
4.49
19.81
12.4
11.0
1.23
1.25
mmol/l
0.08
46
108
126
551
2.71
19.10
4.2
5.6
1.05
1.03
mmol/l
0.55
118
509
415
3096
2.78
19.06
8.3
4.5
—
3.34
—
0
6
122
526
2.73
19.01
3.1
2.9
4.65
6.95
umol/l
3.04
109
464
197
1069
2.37
18.79
2.2
1.6
0.90
1.23
mg/l
0.90
156
837
209
1171
2.32
18.44
2.8
2.1
2.64
2.89
mg/l
0.74
190
1019
75
251
3.33
18.27
10.4
6.5
—
—
—
0
0
42
94
4.78
17.85
1.3
1.2
—
—
—
0
0
365
2609
2.38
17.60
10.2
9.9
4.71
4.06
e9/l
4.20
310
2292
45
109
4.43
17.36
1.4
1.3
713.51
1095.97
e6/l
0.13
35
86
198
1109
2.28
17.24
5.9
3.9
90.96
92.06
%
0.28
191
1092
316
2144
2.23
17.02
7.5
6.4
8.38
8.72
%
1.49
293
2022
44
107
4.40
16.88
1.3
1.2
3.91
13.31
e6/l
0.77
34
81
315
2145
2.21
16.67
7.4
6.3
2.57
2.84
%
1.60
292
2021
314
2142
2.20
16.45
7.5
6.4
0.64
0.70
%
1.02
292
2008
308
2087
2.19
16.39
3.1
2.5
73.45
76.73
nmol/l
1.08
285
1899
150
761
2.37
16.32
5.5
2.8
1.03
0.94
e6/l
0.16
92
401
334
2341
2.22
16.26
7.1
6.3
0.04
0.04
e9/l
0.58
290
2024
333
2333
2.22
16.20
7.1
6.3
0.59
0.57
e9/l
0.72
290
2016
136
663
2.43
16.16
2.0
1.9
28.74
29.10
s
0.38
131
647
434
3416
2.76
16.00
11.8
8.3
77.49
76.83
u/l
0.13
420
3244
343
2444
2.22
15.82
7.1
3.8
0.00
0.00
estimate
-0.00
67
517
262
1685
2.13
15.73
7.7
3.9
57.95
89.13
e6/l
0.60
211
1170
251
1590
2.13
15.66
5.4
3.4
29.68
31.34
u/l
0.42
243
1508
139
695
2.37
15.54
5.7
2.9
4.67
2.49
e6/l
1.26
84
336
210
1245
2.16
15.53
6.2
3.0
0.32
0.46
e6/l
0.69
169
897
161
859
2.27
15.46
4.0
2.8
517.01
522.17
mosm/kgh2o
0.12
148
749
316
2192
2.15
15.45
7.7
6.3
27.19
27.72
%
0.37
295
2087
80
306
2.91
15.43
4.1
3.2
166.27
174.16
ng/l
0.06
66
283
339
2418
2.19
15.40
7.3
6.6
0.19
0.19
e9/l
0.10
307
2129
192
1102
2.19
15.39
3.4
2.4
—
—
—
0
0
335
2382
2.17
15.29
7.1
6.3
1.96
1.93
e9/l
0.14
305
2115
216
1303
2.14
15.19
2.0
1.7
20.13
20.87
nmol/l
0.30
198
1106
311
2155
2.13
15.11
7.5
6.2
58.34
57.47
%
0.64
293
2066
187
1088
2.13
14.26
7.5
3.8
1.02
1.02
kg/l
0.09
139
729
333
2415
2.08
13.73
7.2
3.8
0.00
0.00
estimate
0.50
64
505
338
2469
2.08
13.61
7.2
3.8
0.00
0.64
estimate
0.51
64
478
98
442
2.50
13.60
3.4
2.4
31.13
32.10
u/l
0.12
84
362
25
45
5.79
13.49
2.2
1.4
17.63
28.18
ng/l
0.70
25
45
53
172
3.32
13.48
2.7
2.0
1.78
3.41
ug/l
0.44
43
157
125
632
2.29
13.41
1.3
1.2
—
—
—
0
0
133
700
2.21
12.90
2.0
1.7
1141.27
1212.33
nmol/l
0.45
115
530
282
1957
1.98
12.80
5.8
3.4
6.27
6.19
ph
0.61
161
1136
286
1995
1.98
12.78
2.7
2.0
93.75
96.70
pmol/l
0.53
165
1010
120
610
2.26
12.64
8.0
7.1
103.57
104.00
mmol/l
0.43
120
610
43
127
3.60
12.63
4.3
3.1
—
—
—
0
0
95
440
2.42
12.38
3.6
3.3
7.39
7.39
ph
0.03
49
260
91
417
2.44
12.13
3.3
3.2
2.62
2.08
mmol/l
0.68
81
355
29
66
4.60
12.06
1.6
1.5
—
—
—
0
0
29
66
4.60
12.06
1.6
1.5
—
—
—
0
0
29
66
4.60
12.06
1.6
1.5
—
—
—
0
0
29
66
4.60
12.06
1.6
1.5
—
—
—
0
0
90
412
2.44
12.01
2.6
2.4
0.21
0.22
g/l
0.29
82
391
138
763
2.11
11.68
2.2
2.4
10.92
13.39
umol/l
4.21
127
714
76
328
2.55
11.48
2.6
2.5
20.41
18.79
au/ml
—
9
27
82
370
2.45
11.26
7.6
9.0
—
—
—
0
0
131
719
2.10
11.26
2.1
2.4
2.39
2.34
g/l
0.54
125
670
232
1554
1.90
11.23
3.6
3.3
2.35
2.36
mmol/l
0.62
218
1419
22
42
5.43
11.15
1.3
1.0
—
—
—
0
0
35
98
3.76
11.10
1.8
1.2
—
—
—
0
0
83
380
2.41
11.04
2.5
2.6
10.17
10.58
g/l
0.46
78
349
123
669
2.10
10.78
2.0
2.4
18.07
23.08
%
5.37
113
632
200
1316
1.85
9.93
3.4
3.2
1045.21
1102.16
ng/l
0.08
168
1114
22
30
7.61
9.80
1.0
1.1
0.58
0.49
ratio
0.65
16
17
204
1370
1.81
9.35
7.4
6.3
—
—
—
0
0
30
86
3.64
9.21
3.0
2.6
—
—
—
0
0
95
497
2.12
9.10
1.8
3.3
1.84
1.85
%
0.02
87
453
91
480
2.09
8.51
2.9
2.0
352.33
384.41
nmol/l
0.70
86
455
139
852
1.87
8.42
1.5
1.3
9.47
9.05
u/ml
0.02
43
329
76
376
2.20
8.36
3.9
2.6
0.25
0.57
e6/l
0.59
76
358
34
114
3.12
8.20
4.1
3.4
2.81
2.03
index
0.12
21
69
254
1868
1.71
8.16
7.1
3.6
0.00
0.02
estimate
1.60
57
417
37
136
2.85
7.62
1.6
1.2
9.54
8.56
u/l
0.21
31
104
75
383
2.12
7.60
5.5
2.3
5.94
6.12
ph
1.12
58
246
50
216
2.46
7.50
2.2
1.6
0.22
0.29
mg/l
0.52
24
94
122
1848
0.55
7.41
3.2
3.1
—
—
—
0
0
15
18
8.55
7.36
3.1
1.3
—
—
—
0
0
33
116
2.97
7.36
1.6
1.5
7440.00
16879.76
e6/l
0.90
18
87
26
79
3.41
7.34
1.4
1.4
—
—
—
0
0
377
3137
1.76
7.30
5.2
3.3
46.81
45.16
u/l
0.18
363
2976
114
686
1.85
7.21
1.6
1.4
433.04
465.94
titre
0.10
23
165
39
153
2.68
7.12
3.0
2.0
—
—
—
0
0
146
951
1.75
7.07
1.5
1.3
11.71
30.73
iu/ml
6.53
40
300
234
1729
1.65
7.06
6.2
3.7
19.97
69.90
ng/l
0.86
167
1199
25
76
3.41
7.06
1.4
1.6
—
—
—
0
0
43
178
2.55
7.05
3.2
2.0
—
—
—
0
0
375
3132
1.73
6.97
5.5
4.0
—
0.17
—
0
6
71
368
2.08
6.91
5.2
6.9
9.30
9.12
mmol/l
0.08
65
353
44
187
2.48
6.84
3.2
2.0
—
—
—
0
0
66
335
2.11
6.78
2.4
3.6
84.97
80.75
ng/l
0.17
61
299
78
422
2.00
6.75
3.6
2.2
0.00
0.03
estimate
0.50
14
97
20
54
3.81
6.70
1.5
1.3
—
—
—
0
0
213
1555
1.63
6.63
3.5
3.4
6.90
7.66
mmol/l
1.71
185
1312
137
894
1.73
6.53
1.9
1.7
443.90
22207894.72
pmol/l
0.72
124
752
52
244
2.26
6.49
3.8
2.3
0.61
0.62
%
0.07
52
244
43
188
2.41
6.30
3.2
1.9
—
—
—
0
0
284
2243
1.60
6.26
4.0
3.0
103.89
113.97
ug/l
0.50
276
2106
406
3509
1.75
6.20
5.9
4.4
14.64
14.68
pmol/l
0.12
383
3234
68
361
2.02
6.20
1.9
3.4
65.88
67.20
g/l
0.84
62
337
43
190
2.38
6.16
3.3
1.9
—
—
—
0
0
163
1133
1.64
6.06
1.5
1.3
0.56
1.32
u/ml
2.70
41
317
70
379
1.98
6.04
1.7
3.3
70.04
72.54
e9/l
0.26
56
281
20
59
3.49
5.92
1.7
1.4
0.66
0.58
nmol/l
0.30
20
54
479
4389
2.38
5.88
35.9
15.3
22.63
22.82
mg/l
0.05
450
3608
31
120
2.69
5.83
3.2
1.7
—
—
—
0
0
38
166
2.39
5.59
5.0
2.2
404.51
5321.33
u/l
1.68
14
73
43
201
2.24
5.43
2.6
1.9
—
—
—
0
0
101
636
1.73
5.38
2.4
2.3
149.76
107.35
ug/g
0.50
81
512
184
1350
1.57
5.34
8.4
3.8
0.00
0.01
estimate
0.69
63
480
132
896
1.64
5.30
3.6
2.9
2.44
2.45
mmol/l
0.17
116
808
41
190
2.26
5.29
3.3
1.8
—
—
—
0
0
145
1013
1.60
5.16
1.7
1.5
2.42
2.38
g/l
0.11
93
640
9
9
10.15
5.04
1.0
1.0
11.30
6.16
mg/g
—
9
9
17
51
3.41
4.92
1.8
1.3
—
—
nmol/l
—
0
0
63
353
1.89
4.91
3.5
2.5
6.11
7.20
ug/l
0.21
54
323
193
1455
1.52
4.86
3.1
3.5
29.11
53.66
mg/l
1.93
130
931
52
274
2.00
4.85
2.9
3.6
4.22
4.46
pmol/l
1.03
47
244
453
4122
1.85
4.82
7.4
5.4
1.82
1.88
mu/l
0.41
432
3846
9
10
9.14
4.80
1.0
1.0
—
—
—
0
0
184
1379
1.52
4.74
5.8
3.1
0.02
0.07
estimate
0.41
61
408
67
388
1.84
4.72
1.3
1.2
—
—
—
0
0
16
50
3.27
4.37
1.2
1.4
0.35
0.34
g/l
—
10
36
16
50
3.27
4.37
1.2
1.4
—
—
—
0
0
16
50
3.27
4.37
1.2
1.4
5.10
6.78
g/l
—
10
37
16
50
3.27
4.37
1.2
1.4
2.65
2.78
g/l
—
10
36
88
566
1.67
4.30
3.3
3.1
4.49
5.49
e9/l
0.70
81
495
192
1477
1.48
4.26
3.7
4.1
5.74
9.70
mg/mmol
0.94
118
911
159
1179
1.51
4.22
3.0
2.7
342.38
337.73
umol/l
0.18
144
1044
48
261
1.93
4.11
1.3
1.2
—
—
—
0
0
10
18
5.64
3.99
3.0
1.3
94.10
56.56
nmol/24h
—
10
18
90
600
1.61
3.81
1.9
1.5
—
—
—
0
0
37
189
2.03
3.78
1.5
2.4
1.57
1.38
g/l
0.74
32
173
14
39
3.66
3.72
1.4
1.2
—
—
—
0
0
21
85
2.53
3.68
1.2
1.8
0.69
0.76
g/l
0.11
14
69
33
164
2.08
3.63
1.5
1.8
21.37
21.28
s
0.02
27
148
13
42
3.15
3.39
2.1
1.9
10.98
10.49
%
0.12
13
42
7
10
7.08
3.37
3.3
2.0
12.93
17.25
umol/l
—
7
10
45
258
1.82
3.30
1.6
1.3
19.61
24.72
iu/l
0.62
39
213
31
157
2.04
3.27
1.7
1.4
0.25
0.23
g/l
0.70
25
151
20
84
2.44
3.27
2.9
2.5
—
—
—
0
0
25
492
0.48
3.25
1.3
1.4
—
—
—
0
0
50
301
1.73
3.13
2.0
2.6
—
—
—
0
0
47
282
1.73
2.98
4.0
3.4
7.42
7.42
ph
0.05
39
232
32
170
1.94
2.97
1.4
1.3
—
—
—
0
0
241
2027
1.36
2.92
14.2
11.2
0.00
0.00
e9/l
0.07
190
1673
12
38
3.21
2.87
1.7
1.5
58.00
56.40
%
—
6
30
40
234
1.77
2.78
3.5
2.3
0.00
0.01
estimate
0.49
17
81
79
552
1.51
2.72
1.4
1.3
—
—
—
0
0
28
148
1.94
2.66
1.5
1.4
242.14
288.20
ug/g
0.58
17
90
30
163
1.89
2.63
1.7
1.4
1.35
1.18
g/l
2.07
24
156
166
1335
1.36
2.63
1.5
1.5
—
—
—
0
0
36
209
1.78
2.58
1.2
1.1
—
—
—
0
0
39
234
1.72
2.50
1.1
1.1
—
14.20
—
0
5
116
888
1.40
2.47
2.2
1.9
—
—
—
0
0
35
206
1.75
2.41
1.9
1.9
2.44
5.13
iu/ml
—
9
45
5
8
6.30
2.37
1.0
1.3
—
—
—
0
0
24
126
1.95
2.34
2.2
4.0
1.91
1.89
ratio
0.02
12
73
17
78
2.22
2.33
1.2
1.1
—
—
—
0
0
27
149
1.86
2.29
2.4
2.8
—
—
—
0
0
29
164
1.81
2.28
1.6
1.8
42.00
38.65
nmol/l
0.33
29
157
76
547
1.46
2.27
1.8
1.6
—
—
—
0
0
444
4188
1.45
2.17
7.6
6.3
39.35
39.10
mmol/mol
0.23
426
3969
475
4543
1.62
2.16
30.0
13.7
—
—
—
0
0
18
89
2.06
2.08
1.2
1.1
—
—
—
0
0
15
69
2.21
2.06
1.8
2.6
—
—
—
0
0
7
21
3.36
1.97
1.1
1.4
128.14
146.24
nmol/l
—
7
21
5
11
4.58
1.94
1.2
1.6
1.17
1.19
mmol/l
—
5
11
26
151
1.76
1.91
3.0
3.8
184.36
281.44
mg/l
0.65
11
61
211
1820
1.27
1.90
2.4
2.1
—
—
—
0
0
9
34
2.68
1.87
1.7
3.2
562.00
755.71
mg
—
9
34
6
17
3.56
1.84
1.3
1.2
—
—
—
0
0
481
4638
1.59
1.80
18.4
11.9
26.76
25.98
u/l
0.58
476
4526
8
29
2.79
1.80
2.1
1.3
—
—
—
0
0
6
18
3.36
1.75
1.2
1.2
—
—
—
0
0
57
410
1.44
1.74
4.6
4.9
0.85
0.99
%
0.24
27
138
33
213
1.59
1.67
2.4
2.4
—
—
—
0
0
219
1922
1.24
1.64
2.2
2.0
1.62
1.35
mmol/l
2.35
188
1631
13
249
0.51
1.64
2.4
1.6
—
—
—
0
0
53
386
1.42
1.53
4.5
4.9
0.56
0.52
%
0.08
25
125
94
751
1.31
1.52
1.7
1.7
—
—
—
0
0
9
40
2.27
1.40
1.1
1.2
—
—
—
0
0
59
449
1.35
1.33
3.2
4.5
3.94
16.18
ug/l
0.69
48
367
5
18
2.79
1.29
1.4
3.3
853.40
664.28
u/ml
—
5
18
8
36
2.24
1.24
3.3
2.0
39.79
38.61
%
—
8
36
15
85
1.79
1.24
1.9
5.3
—
—
—
0
0
8
37
2.18
1.22
1.1
1.2
—
—
—
0
0
21
134
1.59
1.16
1.1
1.2
—
—
—
0
0
13
72
1.83
1.16
2.8
3.2
0.86
0.73
nmol/l
—
7
56
8
39
2.07
1.15
1.8
1.4
—
—
—
0
0
0
35
0.00
1.15
0.0
1.2
—
—
—
0
0
0
35
0.00
1.15
0.0
1.1
—
8.12
—
0
11
9
166
0.53
1.09
1.0
1.1
1.54
1.56
g/l
—
9
166
47
358
1.34
1.08
1.6
1.5
—
—
—
0
0
7
32
2.20
1.08
1.7
1.5
—
—
—
0
0
11
59
1.88
1.08
1.5
3.2
—
—
—
0
0
11
59
1.88
1.08
1.1
1.1
1.13
5.75
u/ml
—
6
25
10
174
0.57
0.98
1.1
1.2
0.89
0.90
g/l
—
10
174
7
36
1.96
0.97
1.0
1.0
—
—
—
0
0
10
54
1.87
0.97
1.3
2.7
33.40
33.19
pg
—
10
54
9
51
1.78
0.95
3.7
2.5
—
—
—
0
0
7
37
1.90
0.94
2.0
1.8
—
—
—
0
0
12
70
1.73
0.93
3.7
3.0
4.11
4.60
e9/l
0.28
12
70
46
360
1.31
0.91
1.3
1.2
161.96
145.53
u/ml
0.10
16
146
11
63
1.76
0.90
1.5
1.3
—
—
—
0
0
124
1086
1.19
0.89
4.1
5.1
—
—
—
0
0
15
95
1.60
0.88
1.5
1.7
—
—
—
0
0
14
88
1.61
0.85
1.1
1.1
1.50
1.44
u/ml
—
8
47
48
385
1.27
0.80
4.9
5.0
0.00
0.15
%
3.54
18
114
8
48
1.68
0.79
1.6
1.4
261.38
284.87
mu/l
—
8
39
59
487
1.24
0.78
2.0
1.8
—
—
—
0
0
49
396
1.26
0.78
5.5
5.4
0.00
0.12
%
1.24
19
110
27
202
1.36
0.74
4.2
3.5
—
—
—
0
0
7
39
1.81
0.72
1.0
1.2
119.14
103.77
pmol/l
—
7
39
48
391
1.25
0.72
3.8
4.1
7.38
7.34
ph
0.78
41
285
12
76
1.59
0.72
1.1
1.0
0.10
0.84
u/ml
—
7
40
7
40
1.76
0.71
1.1
3.0
—
—
—
0
0
7
40
1.76
0.71
1.4
1.3
—
—
—
0
0
20
143
1.41
0.71
10.0
9.6
—
—
—
0
0
61
515
1.21
0.67
1.6
1.7
—
—
—
0
0
12
78
1.55
0.66
1.9
2.4
1.96
2.53
mmol/l
—
7
50
435
4238
1.17
0.63
6.2
5.0
6.05
5.93
mmol/l
1.19
409
3935
15
104
1.46
0.63
1.4
1.1
—
—
—
0
0
8
52
1.55
0.59
1.1
1.1
—
—
—
0
0
14
98
1.44
0.57
1.1
1.1
—
—
—
0
0
14
98
1.44
0.57
1.1
1.1
—
—
—
0
0
429
4387
0.86
0.56
5.5
4.9
1.39
1.47
mmol/l
3.87
411
4107
14
100
1.41
0.52
3.3
2.8
60.93
60.06
%
0.08
14
100
9
65
1.39
0.51
1.4
1.2
—
—
—
0
0
131
1206
1.12
0.48
5.5
5.0
8.41
2.10
ug/l
0.70
122
1089
65
730
0.87
0.43
3.2
3.0
0.62
0.73
ug/l
0.86
45
448
5
31
1.62
0.43
1.0
1.1
—
—
—
0
0
6
92
0.65
0.42
1.0
1.1
—
15.10
—
0
34
12
87
1.39
0.42
1.4
1.3
—
169.87
—
0
27
10
138
0.72
0.41
1.3
1.3
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
8
60
1.34
0.40
3.1
2.3
101.38
105.65
mmol/l
—
8
60
8
60
1.34
0.40
3.1
2.3
3.81
4.01
mmol/l
—
8
60
33
279
1.20
0.40
1.2
1.1
—
—
—
0
0
38
326
1.18
0.39
1.3
1.2
—
—
—
0
0
411
4192
0.90
0.39
4.7
4.2
1.52
1.28
mmol/l
4.72
390
3905
5
35
1.43
0.39
1.0
1.0
319.00
254.95
ng/l
—
5
21
5
35
1.43
0.39
1.0
1.0
384.00
636.14
ng/l
—
5
22
9
69
1.31
0.37
1.2
1.1
—
—
—
0
0
9
123
0.73
0.35
1.0
1.1
—
—
—
0
0
66
596
1.12
0.35
1.3
1.3
—
—
—
0
0
6
46
1.31
0.33
1.0
1.3
—
—
—
0
0
41
361
1.15
0.32
5.8
3.5
—
—
—
0
0
12
92
1.31
0.32
1.4
1.2
153.52
21.33
u/l
0.45
12
82
20
165
1.22
0.31
1.5
1.6
8.02
7.75
u/ml
—
5
36
7
54
1.30
0.30
1.3
1.2
—
—
—
0
0
44
392
1.13
0.30
1.2
1.4
—
—
—
0
0
11
87
1.27
0.24
2.7
2.6
4.59
7.94
pmol/l
1.88
11
87
10
78
1.29
0.24
2.3
1.7
—
—
—
0
0
6
81
0.74
0.24
1.2
1.5
—
—
—
0
0
435
4399
0.93
0.22
5.8
5.1
4.62
4.67
mmol/l
0.37
416
4138
5
41
1.22
0.22
2.0
3.4
4.60
15.73
mg/l
—
5
31
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
65.30
—
0
12
0
14
0.00
0.20
0.0
1.0
—
0.50
—
0
9
6
52
1.16
0.19
1.0
1.2
—
—
—
0
0
12
100
1.20
0.18
1.7
2.4
52.37
80.37
ug/min
—
7
57
11
130
0.84
0.16
1.3
1.4
62.00
190.95
pmol/l
0.86
11
125
18
159
1.14
0.15
1.6
1.4
91.93
236.64
miu/ml
—
6
81
9
81
1.11
0.15
1.6
1.9
—
—
—
0
0
23
209
1.11
0.13
1.3
1.2
—
—
—
0
0
55
526
1.05
0.10
1.6
1.5
—
—
—
0
0
5
47
1.06
0.09
1.0
1.1
—
—
—
0
0
5
48
1.04
0.09
1.2
1.2
—
—
—
0
0
11
98
1.13
0.07
1.4
1.3
—
—
—
0
0
50
490
1.02
0.02
1.5
1.5
—
—
—
0
0
16
152
1.05
0.02
1.3
1.3
—
—
—
0
0
14
137
1.02
0.00
1.3
1.1
—
—
—
0
0
11
112
0.98
0.00
3.5
4.3
—
—
—
0
0
446
4459
1.00
0.00
6.6
5.7
2.72
2.74
mmol/l
0.15
427
4179
0
6
0.00
0.00
0.0
2.5
—
—
—
0
0
0
6
0.00
0.00
0.0
2.5
—
—
—
0
0
6
60
1.00
0.00
3.8
2.3
1.26
1.19
mmol/l
—
6
60
0
6
0.00
0.00
0.0
3.5
—
0.97
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.7
—
6104.33
—
0
9
0
5
0.00
-0.00
0.0
7.6
—
9.60
—
0
5
0
5
0.00
-0.00
0.0
3.0
—
189.80
—
0
5
0
8
0.00
-0.00
0.0
1.3
—
0.45
—
0
8
0
5
0.00
-0.00
0.0
3.8
—
49.40
—
0
5
0
5
0.00
-0.00
0.0
1.8
—
288.20
—
0
5
0
5
0.00
-0.00
0.0
5.0
—
6.44
—
0
5
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
34.60
—
0
5
5
49
1.02
-0.00
2.4
3.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
48.00
—
0
8
0
8
0.00
-0.00
0.0
2.3
—
2.13
—
0
8
0
9
0.00
-0.00
0.0
10.2
—
5.64
—
0
9

Mortality – FinRegistry

Association

Association between endpoint G6_CAUDA and mortality.

Females

Parameter HR [95% CI] p-value
G6_CAUDA 1.674 [1.35, 2.08] < 0.001
Birth year 0.996 [0.99, 1.0] 0.302

During the follow-up period (1.1.1998 — 31.12.2019), 270 out of 1360 females with G6_CAUDA died.

Males

Parameter HR [95% CI] p-value
G6_CAUDA 2.282 [1.82, 2.85] < 0.001
Birth year 0.988 [0.98, 1.0] 0.01

During the follow-up period (1.1.1998 — 31.12.2019), 296 out of 1078 males with G6_CAUDA died.

Mortality risk

Mortality risk for people of age

years, who have G6_CAUDA.

N-year risk Females Males
1 0.116% 0.472%
5 0.849% 2.728%
10 2.433% 6.745%
15 5.003% 13.023%
20 8.671% 21.312%

Relationships between endpoints

Index endpoint: G6_CAUDA – Cauda equina syndrome

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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