Hair colour and hair shaft abnormalities

L12_HAIRCOLOUR

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — L67 Hospital discharge: ICD-9 — 7042\|7043 Hospital discharge: ICD-8 — 7040[2-3]\|7040[7-9] Hospital discharge: excluded ICD-8 — 70708 Cause of death: ICD-10 — L67 Cause of death: ICD-9 — 7042\|7043 Cause of death: ICD-8 — 7040[2-3]\|7040[7-9] Cause of death: excluded ICD-8 — 70708 2 out of 7 registries used, show all original rules.	161
4. Check minimum number of events None	161
5. Include endpoints None	161
6. Filter based on genotype QC (FinnGen only)	139

Control definitions (FinnGen only)

Control exclude: L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: L60-L75
Name in latin: Abnormitates coloris et scapi pilorum

NAME	L12_HAIRCOLOUR
CONTROL_EXCLUDE	L12_DISORDSKINAPPENDIX
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L67
HD_ICD_9	7042\|7043
HD_ICD_8	7040[2-3]\|7040[7-9]
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL	70708
COD_MAINONLY
COD_ICD_10	L67
COD_ICD_9	7042\|7043
COD_ICD_8	7040[2-3]\|7040[7-9]
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL	70708
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Hair colour and hair shaft abnormalities based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	1104	455	638
Only index persons	890	379	511
Unadjusted period prevalence (%)
Whole population	0.02	0.01	0.02
Only index persons	0.02	0.01	0.02
Median age at first event (years)
Whole population	27.61	26.71	28.05
Only index persons	25.97	25.46	26.35

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	139	57	82
Unadjusted period prevalence (%)	0.03	0.02	0.04
Median age at first event (years)	27.12	24.90	28.67

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
144: Matched controls
1440

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

70403

ICD-8 Finland

Diseases of hair and hair follicles, Pili retenti (ingrown hair)

+∞

74.6

70409

ICD-8 Finland

Diseases of hair and hair follicles, Alii definiti et NUD

+∞

53.5

70402

ICD-8 Finland

Diseases of hair and hair follicles, Pili incarnati

+∞

11.6

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3035285) Chloride [Moles/volume] in Venous blood

7.34

5.06

4.4

3.3

104.82

105.38

mmol/l

0.14

(3041354) Potassium [Moles/volume] in Venous blood

7.34

5.06

4.4

3.3

4.00

4.10

mmol/l

0.25

(3033705) Calcium.ionized [Moles/volume] in Venous blood

7.34

5.06

4.4

3.3

1.21

1.19

mmol/l

0.72

(1761482) Bacteria [#/volume] in Urine by Culture

4.17

4.35

6.9

4.6

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

281

2.00

3.49

1.9

1.8

427.54

431.34

pmol/l

0.04

239

(3030981) Hyaline casts [#/volume] in Urine by Automated count

117

2.26

2.98

2.3

2.8

0.33

0.23

e6/l

0.25

111

(3021447) Carbon dioxide [Partial pressure] in Venous blood

148

2.11

2.86

8.6

3.9

5.83

5.71

kpa

0.21

143

(3025941) Bacteria identified in Stool by Culture

2.88

2.80

1.2

—

(3012544) pH of Venous blood

150

2.08

2.76

8.6

3.8

7.39

0.07

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

2.36

2.71

3.6

2.5

0.62

0.03

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

2.31

2.58

3.6

2.6

1.57

1.29

0.33

(3023368) Bacteria identified in Blood by Culture

390

1.71

2.44

5.1

5.2

—

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

114

1.99

2.00

2.8

4.3

1.21

1.22

mmol/l

0.22

(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method

2.84

1.97

1.2

1.7

2.10

6.33

mg/l

—

(3004775) Volume in Urine collected for unspecified duration

3.94

1.73

4.2

3.4

866.80

527.88

—

(3042936) Bacteria identified in Isolate by Culture

210

1.67

1.68

2.0

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

236

1.64

1.66

3.8

3.3

0.57

2.14

e6/l

1.70

125

(3013650) Neutrophils [#/volume] in Blood by Automated count

732

1.52

1.63

11.9

10.4

4.29

4.16

e9/l

0.20

631

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

3.08

1.60

1.0

1.3

—

nmol/l

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

3.41

1.53

1.0

1.1

—

(42870588) Differential panel, method unspecified - Blood

457

1.49

1.51

5.7

5.9

—

(3041096) Erythrocytes [Presence] in Urine by Automated

385

1.50

1.47

4.9

3.7

0.00

estimate

-0.00

128

(3044290) Cell count panel - Cerebral spinal fluid

3.20

1.45

1.2

1.3

—

(21494890) Protein electrophoresis panel - 24 hour Urine

3.20

1.45

3.4

1.7

—

(3023183) Ammonium ion [Moles/volume] in Plasma

2.48

1.41

1.4

3.5

38.86

37.33

umol/l

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

668

1.44

1.36

9.4

7.6

1.20

mmol/l

0.31

578

(1761868) Lipid panel - Serum or Plasma

468

1.44

1.31

4.2

3.4

—

(3019309) Folate [Moles/volume] in Red Blood Cells

234

1.53

1.26

1.8

1.7

972.46

1186.93

nmol/l

0.97

180

(3019198) Lymphocytes [#/volume] in Blood

674

1.42

1.26

7.5

6.2

1.68

1.90

e9/l

1.25

590

(3025159) Blasts/Leukocytes in Blood

109

1.74

1.26

3.8

6.7

—

0.34

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

151

0.50

1.23

2.7

8.1

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

2.55

1.16

3.0

1.1

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

2.55

1.16

3.0

1.1

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

120

1.67

1.15

1.2

1.4

—

(3026782) Osmolality of Urine

283

1.47

1.15

5.7

3.1

498.53

558.81

mosm/kgh2o

0.95

240

(3037756) Immunofixation for Serum or Plasma

2.25

1.09

1.7

1.2

—

(3014051) Protein [Presence] in Urine by Test strip

368

1.41

1.09

5.7

3.4

—

0.20

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

508

0.71

1.06

4.1

5.0

21.83

21.98

0.03

269

(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma

115

1.65

1.05

2.7

3.2

30.38

30.52

u/l

0.01

(3017446) Testosterone [Moles/volume] in Serum or Plasma

132

0.51

1.05

1.1

2.6

15.57

13.40

nmol/l

—

120

(3030467) Casts [#/volume] in Urine by Automated count

410

1.38

1.01

4.8

3.3

0.62

0.54

e6/l

0.09

298

(3001604) Monocytes [#/volume] in Blood

661

1.35

1.00

7.5

6.1

0.59

0.60

e9/l

0.03

554

(3006315) Basophils [#/volume] in Blood

662

1.35

0.99

7.5

6.1

0.04

e9/l

0.00

556

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

1.99

0.98

1.0

1.8

—

(3002582) Erythrocytes [#/volume] in Urine

470

1.35

0.95

4.7

3.4

22.70

186.40

e6/l

0.63

359

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

340

1.38

0.93

2.5

2.2

3.15

2.92

mg/l

0.24

289

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

2.11

0.90

2.0

1.2

—

(3032080) INR in Blood by Coagulation assay

669

1.32

0.89

12.5

13.3

1.29

1.22

inr

0.41

557

(3013115) Eosinophils [#/volume] in Blood

679

1.32

0.89

7.8

6.2

0.15

0.20

e9/l

2.87

591

(3030366) Cystatin C [Mass/volume] in Serum or Plasma

1.91

0.89

3.9

3.2

2.47

1.62

mg/l

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

252

1.40

0.87

3.9

3.1

0.96

0.89

e6/l

0.07

138

(3026008) Bacteria identified in Urine by Culture

374

1.34

0.83

4.5

3.0

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

117

1239

0.70

0.82

6.4

6.5

2.46

2.62

mmol/l

1.30

110

1136

(40760892) CBC W Ordered Manual Differential panel - Blood

273

1.37

0.82

5.2

5.8

—

(3021788) Differential panel - Synovial fluid

0.00

0.78

0.0

1.2

—

(40768443) Skin Pathology biopsy report

1.75

0.78

1.2

1.3

—

(3020779) Urea [Moles/volume] in Serum or Plasma

142

1.47

0.77

7.3

6.0

12.55

9.73

mmol/l

0.89

136

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

1.80

0.77

1.0

1.5

—

(3016543) Leukocytes [#/volume] in Cerebral spinal fluid

2.21

0.77

1.2

1.00

2.86

e6/l

—

(3027475) Erythrocytes [#/volume] in Cerebral spinal fluid

2.12

0.75

1.6

1.3

18.60

290.25

e6/l

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

2.12

0.75

1.8

1.1

—

(3024928) Oxygen saturation in Venous blood

1.83

0.73

2.9

2.8

58.46

59.49

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

2.03

0.73

1.2

1.1

—

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

118

1.50

0.73

2.9

2.4

0.19

0.22

g/l

0.74

111

(3018095) Leukocytes [#/volume] in Urine

516

1.28

0.71

5.8

4.2

184.21

69.92

e6/l

0.46

370

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

1.74

0.71

1.0

1.1

—

(3007853) Bacteria identified in Skin by Aerobe culture

155

1.42

0.68

1.6

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

1.81

0.67

2.2

1.3

—

(3044640) Blood type and Crossmatch panel - Blood

452

1.27

0.66

3.2

2.4

—

(3037522) Nuclear Ab [Titer] in Serum

174

1.38

0.65

1.5

1.4

240.00

658.82

titre

—

(36660697) Celiac disease serology panel - Serum

101

0.58

0.65

1.0

1.1

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

247

1.33

0.64

2.0

3.6

0.78

0.81

mmol/l

0.54

234

(3021589) Normoblasts [#/volume] in Blood

602

1.25

0.61

16.9

12.6

0.01

0.00

e9/l

0.23

485

(3000963) Hemoglobin [Mass/volume] in Blood

126

1308

0.71

0.60

39.3

27.1

134.49

135.79

g/l

0.41

126

1295

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

116

1218

0.76

0.60

5.7

4.36

4.52

mmol/l

1.09

109

1126

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

288

1.28

0.58

1.5

1.7

1.61

1.67

mg/l

0.02

232

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.69

0.57

1.2

1.3

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.58

0.57

3.0

2.2

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

634

0.81

0.56

2.3

2.7

—

(36304997) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells [Units/volume] in Blood

1.65

0.56

1.2

1.4

—

0.10

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

499

1.24

0.56

5.1

3.4

—

(3009508) Creatinine [Moles/volume] in Urine

497

0.81

0.52

3.7

3.4

6.91

8.10

mmol/l

1.42

415

(40761511) CBC panel - Blood by Automated count

120

1249

0.76

0.50

24.3

16.0

—

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

638

0.82

0.50

4.7

6.1

2.21

2.52

ug/l

0.22

563

(3028626) Oxygen [Partial pressure] in Capillary blood

1.58

0.49

3.1

2.1

7.83

7.99

kpa

—

(4010399) Spirometry for bronchospasm with prolonged evaluation after bronchodilator

116

0.67

0.48

1.4

1.3

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

825

1.21

0.47

3.6

72.30

53.24

u/l

0.81

774

(1002224) Polysomnography panel

1.45

0.46

1.0

1.1

—

(3003694) ABO and Rh group [Type] in Blood

366

0.81

0.45

1.4

—

(3002385) Erythrocyte [DistWidth] in Red Blood Cells

106

1002

1.22

0.44

34.5

22.7

13.95

13.75

0.67

106

995

(40766189) Gliadin peptide IgG Ab [Units/volume] in Serum by Immunoassay

1.53

0.42

1.4

1.1

—

4.16

—

(43055120) Cytomegalovirus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

1.53

0.42

3.8

8.2

—

161.40

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

0.41

0.0

1.3

—

(4146454) Self-monitoring of blood glucose

0.00

0.41

0.0

2.5

—

(4195642) Thrombophilia screening test

0.00

0.41

0.0

1.2

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

0.41

0.0

2.1

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

137

0.71

0.41

1.3

1.6

—

(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

0.41

0.0

1.3

—

(4268621) Lupus anticoagulant assay

0.00

0.41

0.0

1.8

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

642

1.18

0.40

3.4

2.9

—

estimate

—

(3044355) Beta 2 glycoprotein 1 IgG Ab [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.39

0.0

1.2

—

1.33

—

(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.39

0.0

1.2

—

5.22

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.39

0.0

1.1

—

(3046279) Procalcitonin [Mass/volume] in Serum or Plasma

1.34

0.38

2.1

2.0

1.96

2.80

ug/l

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.34

0.38

2.6

1.5

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.29

0.37

1.2

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

177

0.77

0.35

2.1

1.6

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

117

1211

0.82

0.35

5.5

1.41

1.44

mmol/l

0.33

110

1109

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

286

1.20

0.35

3.9

4.2

17.31

434.61

ng/l

1.92

233

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

520

1.16

0.33

4.9

4.1

0.00

estimate

-0.00

129

(3019977) pH of Arterial blood

184

1.23

0.33

4.5

8.7

7.42

0.01

100

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

110

1142

0.84

0.32

6.0

5.1

1.86

1.96

mu/l

0.40

103

1034

(40761536) Microorganisms panel - Urine sediment

117

0.75

0.28

5.4

3.9

—

(3049717) Cytology report of Urine Cyto stain

1.31

0.28

2.6

2.9

—

(3020891) Body temperature

0.68

0.27

1.4

4.3

37.00

36.89

°c

—

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

1.27

0.26

8.0

3.3

4.30

4.39

pmol/l

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

113

1164

0.86

0.25

5.0

4.7

1.30

1.28

mmol/l

0.12

107

1061

(3048689) Calprotectin [Mass/mass] in Stool

136

0.79

0.24

3.6

2.1

142.73

104.42

ug/g

0.19

110

(40761535) Cells panel - Urine sediment

0.75

0.23

3.1

3.2

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

1.23

0.22

1.0

1.3

—

(3003396) Base excess in Arterial blood by calculation

183

1.17

0.21

4.6

8.7

1.82

0.82

mmol/l

0.63

163

(4094501) Cardiovascular stress test using bicycle ergometer

1.20

0.21

1.2

1.1

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.0

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3018301) Testosterone Free [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.2

—

168.77

—

(4062490) Immunoglobulin typing, IgG

0.00

0.21

0.0

1.5

—

(3006442) Creatine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.9

—

76.10

—

(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection

0.00

0.21

0.0

1.6

—

(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection

0.00

0.21

0.0

1.6

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.1

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.1

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.1

—

(3014037) CD3+CD4+ (T4 helper) cells/cells in Blood

0.00

0.21

0.0

4.4

—

38.43

—

(3014326) Insulin-like growth factor-I [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

2.3

—

22.03

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

0.21

0.0

1.0

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

0.21

0.0

1.0

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.2

—

(21494434) Karyotype in Bone marrow

0.00

0.21

0.0

1.2

—

(4035726) Immunohistochemistry procedure

127

1.20

0.20

1.3

1.4

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.20

0.0

2.5

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

0.20

0.0

1.1

—

(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma

1.23

0.20

8.8

3.1

20.55

75.68

mg/l

—

(3034860) Kappa light chains.free [Mass/volume] in Serum

1.23

0.20

8.8

3.1

60.90

171.64

mg/l

—

(3020682) Albumin/Creatinine [Ratio] in Urine

506

1.11

0.20

4.6

4.0

4.66

9.83

mg/mmol

1.75

332

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.25

0.19

1.9

1.5

—

(3009261) Glucose [Presence] in Urine by Test strip

706

1.10

0.19

5.5

4.1

0.00

estimate

-0.00

142

(4024509) Urine culture

1.20

0.18

1.9

2.3

—

(3035350) Ketones [Presence] in Urine by Test strip

689

1.09

0.16

5.4

4.1

0.00

estimate

-0.00

153

(3017143) Hepatitis C virus Ab [Presence] in Serum

130

0.83

0.16

2.2

1.5

—

(3012516) Albumin [Mass/volume] in Urine

499

0.91

0.16

3.9

3.5

36.07

53.41

mg/l

0.77

338

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

0.75

0.16

2.0

1.8

—

(40768797) Stomach Pathology biopsy report

181

0.87

0.15

1.4

1.3

—

(3029937) Albumin [Presence] in Urine by Test strip

386

0.91

0.15

3.6

4.0

0.00

estimate

-0.00

145

(3000492) Spirometry study

118

0.84

0.15

1.7

1.4

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

120

1221

0.90

0.14

26.9

17.9

28.29

24.68

mg/l

0.55

107

994

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

169

0.87

0.13

3.8

3.4

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

564

1.08

0.13

4.9

4.1

37.73

43.03

ng/l

0.15

436

(3022145) Colonoscopy Study observation

179

0.88

0.13

1.2

1.3

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

168

0.88

0.12

1.1

1.4

—

(3021601) Nitrite [Presence] in Urine by Test strip

685

1.07

0.12

5.5

4.1

0.00

estimate

-0.00

156

(3019060) Gas panel - Arterial blood

1.17

0.12

1.9

4.5

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

339

1.08

0.11

3.0

2.5

—

(3019150) Specific gravity of Urine by Refractometry

290

0.92

0.11

2.9

4.4

1.01

1.02

kg/l

1.53

197

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

1.17

0.11

7.9

4.1

24.62

24.38

mmol/l

—

(3000991) Gas panel - Venous blood

135

1.12

0.10

12.7

10.5

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

1.04

0.09

1.0

2.0

—

(3001334) Neutrophil cytoplasmic Ab [Units/volume] in Serum

1.14

0.09

1.0

1.4

—

(3015235) Bicarbonate [Moles/volume] in Capillary blood

1.07

0.09

3.5

2.2

28.05

24.20

mmol/l

—

(40768804) Tissue Pathology biopsy report

522

1.06

0.08

3.4

2.1

—

(3022313) Gas panel - Capillary blood

1.04

0.07

2.9

3.3

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

148

1.09

0.06

2.0

1.6

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

213

0.93

0.06

1.6

1.3

1.46

9.98

u/ml

—

(3000494) Fungus identified in Specimen by Culture

168

1.08

0.06

1.2

1.5

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

237

1.07

0.06

1.4

1.3

23.41

41.33

iu/ml

—

(3002256) Pathology report gross observation

178

1.08

0.06

1.9

1.3

—

(40758558) Short blood count panel - Blood

402

0.96

0.04

7.4

6.0

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.09

0.03

1.4

1.6

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

940

0.97

0.03

5.2

4.1

14.82

14.87

pmol/l

0.07

838

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

177

0.96

0.01

2.6

2.1

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

237

0.96

0.01

2.2

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

437

0.98

0.01

2.7

2.2

227.40

181.65

u/l

0.30

416

(3000850) Epithelial cells [#/volume] in Urine

326

0.98

0.00

4.3

2.7

4.14

3.94

e6/l

0.08

292

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

604

1.02

0.00

2.2

2.1

83.59

95.55

pmol/l

1.33

326

(3005719) IgG [Mass/volume] in Serum or Plasma

104

0.96

0.00

1.2

2.3

10.61

9.79

g/l

—

(3004588) Protein electrophoresis panel - Serum or Plasma

107

1.03

0.00

2.8

1.5

—

(3015736) pH of Urine

533

0.99

0.00

5.7

3.7

6.53

6.19

2.03

295

(3009343) pH of Capillary blood

108

1.02

0.00

3.1

3.2

7.39

7.42

0.50

(3015377) Calcium [Moles/volume] in Serum or Plasma

464

0.99

0.00

3.0

3.6

2.35

mmol/l

0.02

416

(40757494) Bilirubin.total [Moles/volume] in Blood

0.00

0.0

1.3

—

(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells

0.00

0.0

2.7

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.8

—

(3028433) Virus identified in Specimen by Culture

0.00

0.0

1.3

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.8

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.0

1.7

—

55.02

—

(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells

0.00

0.0

2.7

—

(3028026) IgM [Mass/volume] in Serum or Plasma

1.00

0.00

1.6

2.0

2.31

1.16

g/l

—

(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.5

—

(4015189) Microbial culture of sputum

0.00

0.0

3.7

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.8

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.8

—

(42529528) Centromere protein B Ab [Units/volume] in Serum by Line blot

0.00

0.0

1.0

—

(3013637) Mi-2 Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(40760543) Extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.0

—

(3028371) Actinomyces sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.2

—

(3028286) Albumin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

-0.00

0.0

1.0

—

44.44

—

(37208534) Antinuclear antibody arbitrary concentration in serum

0.00

-0.00

0.0

1.0

—

(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.3

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

3.3

—

4.59

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

3.0

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

-0.00

0.0

2.1

—

(3037692) Legionella sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.3

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.2

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

6.0

—

74.59

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

-0.00

0.0

2.0

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex

0.00

-0.00

0.0

1.1

—

(3020491) Glucose [Moles/volume] in Blood

0.00

-0.00

0.0

2.2

—

7.32

—

(42529598) SUMO-activating enzyme subunit 1 Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(37020445) Astrovirus RNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.3

—

(3012565) Volume of 24 hour Urine

0.00

-0.00

0.0

2.0

—

2183.33

—

(37021247) Adenovirus 40+41 DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(40758355) Pancreatic polypeptide [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

3.2

—

56.54

—

(42528593) TIF1-gamma Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

-0.00

0.0

3.0

—

(3004490) Bicarbonate [Moles/volume] standard in Capillary blood

0.91

-0.00

2.4

4.1

24.50

25.42

mmol/l

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

0.96

-0.00

2.4

2.7

—

(3016244) Insulin [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.9

—

11.29

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

-0.00

0.0

1.0

—

(3017704) Immunofixation for Urine

0.00

-0.00

0.0

1.0

—

(3006576) Bicarbonate [Moles/volume] in Blood

0.00

-0.00

0.0

4.6

—

25.46

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

-0.00

0.0

1.3

—

(3019897) Erythrocyte [DistWidth] in Red Blood Cells by Automated count

0.00

-0.00

0.0

2.0

—

13.20

—

(42529582) MDA5 Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(3016724) Homocysteine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

13.71

—

(3050898) Methicillin resistant Staphylococcus aureus [Presence] in Genital specimen by Organism specific culture

0.00

-0.00

0.0

2.2

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.6

—

(3023511) Choriogonadotropin [Units/volume] in Urine

0.00

-0.00

0.0

1.6

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

-0.00

0.0

1.1

—

(3023709) Somatotropin [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

2.4

—

1.58

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

3.0

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

-0.00

0.0

1.4

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

3.3

—

10.60

—

(3022058) Hepatitis B virus DNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(40758292) HTLV I+II Ab panel - Serum

0.00

-0.00

0.0

1.6

—

(3015024) Glucose [Moles/volume] in Serum or Plasma --1 hour post dose glucose

0.00

-0.00

0.0

1.6

—

8.02

—

(3020911) Cortisol [Moles/time] in 24 hour Urine

0.00

-0.00

0.0

1.0

—

53.60

—

(4133840) Spirometry

0.00

-0.00

0.0

1.2

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

170

1.00

-0.00

2.2

—

Mortality – FinRegistry

↥

Association

Association between endpoint L12_HAIRCOLOUR and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_HAIRCOLOUR.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: L12_HAIRCOLOUR – Hair colour and hair shaft abnormalities

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Hair colour and hair shaft abnormalities

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints