Benign neoplasm: Scapula and long bones of upper limb

CD2_BENIGN_BONE_SCAPULA_LONG_UPPER

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D16.0&
  • Hospital discharge: ICD-9 2134
  • Hospital discharge: ICD-8 21303
  • Cause of death: ICD-10 D16.0&
  • Cause of death: ICD-9 2134
  • Cause of death: ICD-8 21303

2 out of 7 registries used, show all original rules.

419

4. Check minimum number of events

None

419

5. Include endpoints

None

419

6. Filter based on genotype QC (FinnGen only)

385

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D16
Name in latin
Neoplasma benignum scapulae sive ossium longorum membri superioris

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3001 1340 1651
Only index persons 2788 1256 1532
Unadjusted period prevalence (%)
Whole population 0.04 0.04 0.05
Only index persons 0.05 0.05 0.06
Median age at first event (years)
Whole population 28.48 34.17 23.81
Only index persons 27.91 34.14 22.80

-FinnGen-

Key figures

All Female Male
Number of individuals 385 202 183
Unadjusted period prevalence (%) 0.08 0.07 0.08
Median age at first event (years) 35.56 35.71 35.40

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
397
Matched controls
3970
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D16.0
ICD-10 Finland
Benign neoplasm: Scapula and long bones of upper limb
+∞
307.7
279
*
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
36.8
101.6
65
21
21303
ICD-8 Finland
Benign neoplasm of bone and cartilage, Ossium longorum extremitatis superioris et scapulae
+∞
93.5
86
*
NBR20
NOMESCO Finland
Intralesional or marginal excision of soft tissue tumour of shoulder or upper arm
198.8
51.2
52
*
2134A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Scapula and long bones of upper limb
+∞
34.9
33
*
NB1CG
NOMESCO Finland
Shoulder and humerus extensive MRI examination with high intensity magnet
10.2
33.2
39
42
D16.1
ICD-10 Finland
Benign neoplasm: Short bones of upper limb
96.4
25.0
27
*
9102
FHL
Trepanation or removal of the local bone process
31.1
22.2
29
10
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
4.0
17.4
54
151
D16.2
ICD-10 Finland
Benign neoplasm: Long bones of lower limb
23.1
17.1
24
11
NDR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of wrist or hand
14.0
14.9
25
19
NK6BN
NOMESCO Finland
Bone dynamic isotope examination
77.9
13.7
15
*
NGR20
NOMESCO Finland
Intralesional or marginal excision of tumor of knee or lower leg
61.7
10.7
12
*
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
33.5
10.4
13
*
NB1BG
NOMESCO Finland
Shoulder and humerus MRI examination with high intensity magnet
5.0
10.1
22
46
NB6AA
NOMESCO Finland
Humerus X-ray examination
8.4
9.5
20
25
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
5.1
9.4
20
41
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.1
9.2
118
675
M47.9
ICD-10 Finland
Spondylosis, unspecified
4.9
8.7
19
40
NCR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of elbow or forearm
81.6
7.4
8
*
GA1CG
NOMESCO Finland
Extensive MRI of chest
81.6
7.4
8
*
9101
FHL
Bone biopsy
+∞
7.3
7
*
NB4AA
NOMESCO Finland
Scapula X-ray examination
20.5
7.2
10
5
L08
ICPC
Shoulder symptom/complaint
1.9
6.9
101
599
NB1AD
NOMESCO Finland
Shoulder CT examination
6.9
6.9
16
24
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
2.7
6.8
36
139
N02AX02
ATC
tramadol; systemic, rectal
1.7
6.7
171
1201
NBR30
NOMESCO Finland
Extensive or radical excision of soft tissue tumour of shoulder or upper arm
+∞
6.3
6
*
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
5.9
6.2
16
28
A03FA02
ATC
cisapride; oral, rectal
2.8
6.2
30
111
M01AH05
ATC
etoricoxib; oral
1.7
6.0
256
2042

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
16
50
3.29
4.38
1.7
1.3
—
—
—
0
0
173
1356
1.49
3.66
2.2
2.1
—
—
—
0
0
189
1513
1.48
3.57
2.6
2.5
75.33
74.49
nmol/l
0.16
179
1385
12
32
3.83
3.41
1.6
1.3
70.71
49.62
%
—
7
26
76
508
1.61
3.28
1.6
1.3
375.00
554.56
titre
0.78
16
103
95
673
1.54
3.19
1.4
1.3
11.76
26.72
iu/ml
3.54
29
214
117
872
1.48
3.08
2.6
2.8
334.07
342.54
umol/l
0.44
107
780
16
62
2.65
3.08
4.2
3.3
—
—
—
0
0
140
1089
1.44
2.94
2.1
2.3
—
—
—
0
0
13
47
2.83
2.84
1.5
1.2
—
—
—
0
0
87
629
1.49
2.63
1.4
1.3
1.15
8.43
u/ml
3.90
36
243
12
44
2.78
2.57
1.1
1.4
0.59
0.51
nmol/l
0.47
12
39
5
8
6.31
2.38
4.4
2.5
—
—
—
0
0
86
644
1.43
2.16
1.5
1.7
398.52
29982480.13
pmol/l
0.72
67
557
170
1425
1.34
2.13
5.9
6.6
1.21
1.21
mmol/l
0.05
154
1322
125
1007
1.35
2.02
3.4
3.6
24.66
54.34
mg/l
2.85
80
672
44
292
1.57
1.98
1.6
2.4
10.02
10.43
g/l
0.33
37
271
185
1583
1.32
1.97
6.6
7.2
1.21
1.21
mmol/l
0.04
156
1381
127
1031
1.34
1.94
3.9
4.3
4.31
9.61
mg/mmol
2.34
77
668
7
22
3.22
1.89
1.0
1.1
—
—
—
0
0
16
79
2.07
1.88
1.2
1.5
—
—
—
0
0
15
74
2.07
1.77
1.7
1.4
10626.00
13451.05
e6/l
—
10
57
6
18
3.37
1.75
1.0
1.1
—
—
—
0
0
6
18
3.37
1.75
1.0
1.1
—
—
—
0
0
6
18
3.37
1.75
1.0
1.1
—
—
—
0
0
9
36
2.53
1.75
3.3
1.9
84.50
90.71
%
—
9
36
169
1446
1.29
1.74
3.4
3.2
6.30
6.15
ph
0.87
83
846
209
1844
1.28
1.68
3.9
3.6
0.00
0.83
estimate
0.50
39
360
36
238
1.56
1.67
2.9
2.5
5.13
8.96
ug/l
1.45
31
214
282
2587
1.31
1.66
8.0
8.1
74.90
77.25
u/l
0.61
274
2469
5
14
3.60
1.62
1.8
1.9
—
—
—
0
0
135
1131
1.29
1.61
2.3
3.3
2.35
2.36
mmol/l
0.54
121
1037
59
436
1.41
1.60
1.4
1.5
—
—
—
0
0
218
1943
1.27
1.57
4.5
5.0
6.30
6.62
mmol/l
1.82
208
1832
5
15
3.36
1.53
2.4
1.3
0.00
0.00
estimate
—
5
15
7
27
2.62
1.52
1.0
1.1
—
—
—
0
0
12
58
2.10
1.50
2.7
3.7
3.55
4.56
e9/l
1.11
12
58
54
398
1.41
1.49
1.4
1.4
—
—
—
0
0
106
868
1.30
1.49
4.6
5.1
—
—
—
0
0
9
37
2.46
1.49
1.1
1.4
—
—
—
0
0
27
172
1.61
1.47
2.9
7.1
—
—
—
0
0
37
254
1.50
1.47
1.4
1.3
572.10
321.37
u/ml
0.25
32
241
59
444
1.39
1.45
1.4
1.2
—
—
—
0
0
205
1826
1.25
1.44
4.0
3.5
0.02
0.00
estimate
0.49
43
385
39
272
1.48
1.44
4.1
4.4
7.31
7.32
ph
0.13
28
196
358
3427
1.45
1.42
17.3
16.1
3.96
3.97
mmol/l
0.18
342
3357
9
40
2.28
1.41
1.0
1.5
—
—
—
0
0
103
847
1.29
1.40
2.1
2.1
2.74
2.80
mg/l
0.10
89
748
12
60
2.03
1.39
1.8
1.2
—
—
—
0
0
15
82
1.86
1.37
1.0
1.1
—
—
—
0
0
15
82
1.86
1.37
1.0
1.1
—
—
—
0
0
35
242
1.49
1.35
3.5
4.1
1.21
1.22
mmol/l
0.44
28
213
12
61
2.00
1.34
1.0
1.1
1.19
4.40
u/ml
—
6
32
0
41
0.00
1.32
0.0
13.8
—
822.61
—
0
41
357
3424
1.42
1.31
17.1
15.9
139.83
139.73
mmol/l
0.37
341
3364
9
43
2.12
1.31
3.6
3.0
—
—
—
0
0
5
18
2.80
1.29
1.0
1.1
—
—
—
0
0
14
77
1.85
1.27
1.1
1.0
7.22
6.20
u/ml
—
8
49
22
139
1.62
1.26
1.2
1.3
—
—
—
0
0
161
1414
1.23
1.24
4.0
4.9
36.48
36.51
g/l
0.02
154
1339
12
63
1.93
1.24
1.0
1.1
13.12
1.43
u/ml
—
6
37
8
37
2.19
1.22
1.8
1.4
19.06
30.29
ng/l
—
8
37
5
19
2.65
1.22
1.0
1.1
—
—
—
0
0
30
206
1.49
1.21
4.9
10.1
92.91
93.65
%
0.16
30
206
201
1810
1.22
1.21
4.0
3.5
0.00
0.00
estimate
-0.00
41
386
12
64
1.90
1.19
1.0
1.1
—
—
—
0
0
59
460
1.33
1.18
1.2
1.3
—
—
—
0
0
198
1784
1.22
1.17
4.9
6.6
10.55
11.13
umol/l
0.55
187
1705
13
72
1.83
1.16
1.1
1.1
0.77
1.84
u/ml
—
6
43
8
39
2.07
1.16
1.0
1.2
—
—
—
0
0
5
20
2.52
1.15
3.6
4.3
80.20
156.65
nmol/l
—
5
20
356
3427
1.38
1.14
15.9
14.2
24.12
22.03
mg/l
0.46
288
2778
15
88
1.73
1.13
1.1
1.1
0.34
1.71
u/ml
—
8
56
7
30
2.36
1.13
2.0
2.0
37.24
39.40
%
—
7
30
8
40
2.02
1.12
2.6
2.4
—
—
—
0
0
13
73
1.81
1.12
1.3
1.4
0.95
0.90
nmol/l
0.11
13
65
130
1129
1.23
1.09
3.3
3.4
8.22
8.16
mmol/l
0.04
108
973
24
161
1.52
1.09
1.1
1.1
—
—
—
0
0
45
341
1.36
1.09
4.5
9.5
5.34
5.17
kpa
0.46
45
329
45
341
1.36
1.09
4.5
9.5
12.45
12.21
kpa
0.10
45
330
38
280
1.39
1.09
4.6
3.5
—
—
—
0
0
12
67
1.82
1.05
1.8
3.4
5.06
8.81
pmol/l
1.74
12
67
16
98
1.66
1.05
1.1
1.2
—
—
—
0
0
19
122
1.59
1.04
2.1
1.3
—
—
—
0
0
5
22
2.29
1.03
1.0
1.1
—
—
—
0
0
178
1603
1.20
1.02
2.7
2.7
—
—
estimate
—
0
0
41
310
1.36
1.02
4.4
10.1
94.26
95.57
%
0.42
41
301
116
1004
1.22
1.00
4.5
3.7
0.05
0.02
estimate
0.30
38
369
162
1450
1.20
0.99
16.0
11.3
1.22
1.17
inr
0.63
137
1193
19
124
1.56
0.98
2.3
1.6
1.10
1.19
g/l
0.57
19
119
5
23
2.19
0.98
2.4
3.7
260.40
965.57
mg
—
5
23
112
970
1.22
0.96
4.2
4.2
7.40
7.40
ph
0.03
82
689
105
905
1.22
0.95
3.5
2.8
—
—
—
0
0
44
341
1.33
0.94
4.5
9.6
7.40
7.41
ph
0.54
25
193
6
27
2.24
0.94
1.0
1.6
13.62
10.88
umol/l
—
6
27
6
27
2.24
0.94
1.7
1.1
129.33
107.22
pmol/l
—
6
27
17
110
1.57
0.92
1.0
1.1
—
—
—
0
0
39
298
1.34
0.92
4.5
10.2
128.38
121.62
g/l
1.61
39
290
14
218
0.63
0.91
1.3
1.7
—
—
—
0
0
19
127
1.52
0.90
2.0
1.8
—
—
—
0
0
117
1024
1.20
0.90
5.6
6.6
—
—
—
0
0
12
71
1.71
0.89
1.1
1.0
1.26
3.83
u/ml
—
6
38
371
3615
1.40
0.89
19.5
17.9
76.21
76.21
umol/l
0.00
363
3577
13
79
1.67
0.89
3.2
3.5
57.15
59.79
%
0.35
13
79
8
140
0.56
0.84
3.9
3.4
28.60
24.66
mmol/l
—
8
135
23
317
0.71
0.84
3.4
3.5
6.03
5.74
kpa
0.46
23
307
8
46
1.75
0.83
1.9
2.4
—
—
—
0
0
6
33
1.83
0.79
1.0
1.3
—
—
—
0
0
268
2535
1.18
0.79
3.5
3.3
43.84
43.87
u/l
0.00
255
2429
23
313
0.72
0.79
3.3
3.5
7.38
7.38
ph
0.12
18
171
23
166
1.41
0.77
2.5
2.2
0.00
0.00
estimate
—
7
62
6
34
1.78
0.76
3.7
4.2
—
51.21
—
0
15
22
158
1.42
0.76
1.9
2.5
4.00
6.20
iu/ml
—
8
43
11
172
0.63
0.75
3.5
2.4
0.56
0.61
%
0.29
11
172
7
38
1.86
0.74
2.0
3.7
2.83
7.29
nmol/l
—
7
38
5
26
1.93
0.71
1.2
1.7
—
523.00
—
0
19
30
231
1.32
0.70
1.8
1.5
2.90
1.15
g/l
0.61
25
217
130
1175
1.16
0.67
6.1
5.9
—
—
—
0
0
101
895
1.17
0.67
1.7
1.6
21.00
21.35
nmol/l
0.09
91
775
184
1708
1.14
0.65
3.1
3.0
113.87
105.11
ug/l
0.30
168
1624
10
62
1.63
0.65
2.4
2.0
5.98
5.18
mmol/24h
—
10
55
50
417
1.23
0.64
4.7
6.3
1.00
1.05
mmol/l
0.73
50
389
94
832
1.17
0.64
1.4
1.4
2.20
2.40
g/l
0.61
60
530
71
614
1.19
0.63
3.4
3.8
1757.02
414.14
ng/l
0.41
51
442
138
1259
1.15
0.63
4.4
3.5
33.72
83.54
ng/l
0.50
90
814
153
1406
1.14
0.63
2.2
2.0
101.84
96.11
pmol/l
0.62
83
758
5
30
1.67
0.61
2.2
3.0
—
—
—
0
0
58
494
1.20
0.61
2.1
2.4
89.75
108.58
ug/g
0.41
49
397
25
192
1.32
0.61
2.0
1.5
0.56
0.31
mg/l
0.75
11
87
335
3252
1.19
0.61
5.1
4.6
5.95
5.88
mmol/l
0.43
311
3045
0
20
0.00
0.60
0.0
2.3
—
—
—
0
0
28
219
1.30
0.60
1.3
1.3
—
39.00
—
0
16
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
278
2664
1.15
0.59
4.6
4.3
14.51
14.58
pmol/l
0.19
260
2476
363
3554
1.25
0.57
13.8
12.6
—
—
—
0
0
39
322
1.23
0.56
1.4
1.6
—
—
—
0
0
12
170
0.70
0.54
1.0
1.1
0.84
0.91
g/l
0.52
12
170
119
1085
1.14
0.54
3.0
3.3
25.84
111.08
e6/l
0.80
95
836
21
271
0.76
0.54
3.1
2.7
4.68
4.53
kpa
0.12
21
262
61
529
1.18
0.54
2.8
3.0
2.37
2.19
e6/l
0.05
35
258
9
135
0.66
0.52
3.0
8.0
1.94
1.57
%
—
9
123
6
40
1.51
0.52
1.0
1.1
—
—
—
0
0
22
171
1.30
0.51
5.5
12.1
16.37
15.88
%
0.62
22
162
58
507
1.17
0.47
1.9
1.6
1165.52
1158.56
nmol/l
0.02
42
390
12
165
0.72
0.47
1.0
1.1
1.61
1.55
g/l
0.22
12
165
8
119
0.67
0.46
3.0
8.8
0.65
0.92
%
—
8
107
8
120
0.66
0.46
2.8
1.9
—
—
—
0
0
326
3178
1.14
0.45
5.5
5.2
1.77
1.86
mu/l
0.95
303
2986
18
140
1.30
0.42
2.7
2.2
—
—
—
0
0
113
1043
1.12
0.42
5.9
5.0
2.06
2.57
ug/l
0.46
107
952
6
94
0.63
0.42
1.3
1.8
—
—
—
0
0
6
95
0.63
0.42
1.7
1.3
—
—
—
0
0
13
96
1.37
0.42
2.9
2.1
3.16
5.37
iu/l
—
5
43
59
523
1.15
0.41
2.0
2.5
14.78
13.68
umol/l
0.47
53
494
379
3743
1.28
0.41
23.6
21.8
257.15
251.69
e9/l
1.01
368
3691
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
74
667
1.13
0.41
1.6
1.7
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
327
3194
1.13
0.41
5.9
5.9
38.59
38.90
mmol/mol
0.26
307
3045
88
803
1.12
0.40
1.9
2.0
—
—
—
0
0
102
939
1.12
0.40
3.0
3.1
0.36
0.34
e6/l
0.06
76
698
379
3744
1.27
0.40
23.6
21.7
90.38
90.68
fl
0.72
373
3716
135
1264
1.10
0.39
3.5
3.9
23.93
88.56
e6/l
1.65
98
892
379
3745
1.27
0.39
23.6
21.7
30.09
30.28
pg
1.44
373
3716
379
3745
1.27
0.39
23.9
22.1
52.17
41.00
%
0.51
373
3715
379
3745
1.27
0.39
23.6
21.8
4.58
4.57
e12/l
0.14
367
3685
32
271
1.20
0.38
6.6
8.0
7.73
9.13
mmol/l
0.74
32
263
37
318
1.18
0.38
1.3
1.2
—
—
—
0
0
379
3746
1.26
0.38
23.7
21.8
6.57
6.68
e9/l
0.53
367
3685
11
81
1.37
0.36
2.2
2.6
10.13
131.81
ug/min
—
6
50
146
1545
0.91
0.36
2.8
3.0
—
—
—
0
0
6
41
1.47
0.36
2.2
1.1
—
—
—
0
0
14
108
1.31
0.35
1.6
1.3
217.73
325.16
ug/g
—
6
58
379
3748
1.25
0.35
23.9
21.9
137.59
137.48
g/l
0.05
373
3719
100
927
1.11
0.35
1.4
1.3
1.56
1.25
u/ml
0.18
25
263
6
43
1.40
0.35
1.2
1.2
263.33
234.92
pmol/l
—
6
37
24
286
0.83
0.35
1.9
2.1
5.81
6.16
ph
1.97
16
187
19
154
1.25
0.34
2.7
2.4
8333.05
5640.89
u/l
—
6
62
81
745
1.11
0.33
2.5
2.7
3.25
5.22
e6/l
1.49
73
684
114
1068
1.09
0.32
2.4
2.5
56.31
64.04
u/l
0.66
105
1004
22
185
1.20
0.30
4.1
9.4
25.60
24.59
mmol/l
0.74
22
175
94
877
1.09
0.29
4.7
4.4
—
—
—
0
0
31
270
1.16
0.29
5.6
8.8
—
—
—
0
0
13
162
0.80
0.29
1.2
1.6
—
—
—
0
0
50
452
1.12
0.28
1.2
1.4
—
—
—
0
0
188
1810
1.07
0.27
7.1
6.3
0.59
0.57
e9/l
0.70
172
1563
110
1038
1.08
0.27
3.5
2.9
0.08
0.08
estimate
0.01
38
319
18
150
1.21
0.27
1.1
1.5
330.67
245.62
miu/ml
—
9
81
5
71
0.70
0.26
4.8
3.6
—
—
—
0
0
9
75
1.20
0.25
1.0
1.1
—
—
—
0
0
6
85
0.70
0.24
1.0
1.3
—
—
—
0
0
188
1817
1.07
0.24
7.1
6.3
0.04
0.04
e9/l
0.39
168
1570
146
1400
1.07
0.23
4.2
3.4
0.08
0.01
estimate
0.40
37
336
5
38
1.32
0.23
1.2
1.2
122.58
173.49
pmol/l
—
5
38
5
40
1.25
0.22
1.0
1.3
—
—
—
0
0
156
1619
0.94
0.22
12.6
10.8
0.00
0.00
e9/l
0.60
131
1326
207
2011
1.06
0.22
7.8
10.1
4.15
4.02
e9/l
0.38
183
1758
38
418
0.90
0.21
1.6
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
2.1
—
15.31
—
0
10
0
10
0.00
0.21
0.0
1.1
—
0.80
—
0
5
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
13
155
0.83
0.20
1.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
2.6
—
0.60
—
0
14
167
1725
0.94
0.20
7.2
6.3
28.10
28.20
%
0.04
161
1646
21
239
0.87
0.20
1.2
1.2
—
—
—
0
0
32
289
1.12
0.19
4.3
4.7
0.71
0.55
%
—
7
80
66
619
1.08
0.19
2.4
2.8
2.42
2.44
mmol/l
1.63
60
547
85
807
1.07
0.18
2.0
1.7
0.67
1.27
mg/l
3.48
68
620
76
802
0.94
0.18
4.5
3.6
1.02
1.02
kg/l
0.12
55
533
7
60
1.17
0.18
1.9
1.5
—
—
—
0
0
29
263
1.11
0.17
2.3
2.8
76.65
71.86
e9/l
0.27
23
187
55
517
1.07
0.16
1.6
1.5
—
—
—
0
0
26
285
0.91
0.14
1.6
1.4
—
—
—
0
0
21
232
0.90
0.13
1.1
1.1
—
—
—
0
0
102
1056
0.95
0.13
1.6
1.5
—
—
—
0
0
13
148
0.87
0.12
3.9
3.3
—
—
—
0
0
14
123
1.14
0.12
1.3
1.6
50.22
56.56
ug/l
0.28
14
103
47
444
1.07
0.12
1.9
1.8
—
—
—
0
0
17
189
0.89
0.12
1.2
1.8
—
—
—
0
0
12
137
0.87
0.12
1.8
1.9
1.37
1.41
g/l
0.06
12
120
190
1863
1.04
0.12
7.1
6.3
1.83
1.96
e9/l
0.90
175
1649
21
191
1.11
0.12
1.2
1.2
—
—
—
0
0
68
652
1.05
0.11
3.4
3.0
0.79
0.73
ug/l
0.22
44
385
52
495
1.06
0.11
1.7
1.7
—
—
—
0
0
5
46
1.09
0.09
2.4
3.4
1.60
1.20
%
—
5
41
21
194
1.09
0.09
2.8
2.3
—
—
—
0
0
50
479
1.05
0.09
2.8
2.1
—
—
—
0
0
42
439
0.95
0.08
5.1
6.9
103.14
104.22
mmol/l
0.88
42
439
19
205
0.92
0.08
1.2
1.7
—
—
—
0
0
343
3450
0.96
0.08
5.4
5.4
2.83
2.78
mmol/l
0.52
323
3265
343
3410
1.04
0.07
5.1
4.9
4.65
4.68
mmol/l
0.26
320
3238
15
137
1.10
0.07
1.4
1.8
—
—
—
0
0
8
77
1.04
0.07
1.1
1.3
—
—
—
0
0
40
417
0.95
0.07
2.0
1.6
—
—
—
0
0
32
305
1.05
0.06
2.4
2.1
0.11
0.00
estimate
—
9
73
9
101
0.89
0.06
1.0
1.1
—
—
—
0
0
151
1490
1.02
0.05
1.9
2.0
1.38
1.39
mmol/l
0.07
127
1281
323
3247
0.97
0.05
4.3
4.1
1.30
1.29
mmol/l
0.12
305
3052
165
1670
0.98
0.05
7.2
6.3
0.64
0.68
%
0.47
156
1570
30
287
1.05
0.05
4.8
4.9
0.40
0.16
%
—
5
69
166
1679
0.98
0.05
7.2
6.4
9.00
8.71
%
0.76
157
1589
166
1673
0.99
0.03
7.1
6.3
2.89
2.84
%
0.12
158
1580
11
118
0.93
0.03
3.8
3.6
24.81
24.95
mmol/l
0.07
11
113
361
3619
0.97
0.02
12.0
11.3
28.14
27.62
u/l
0.21
352
3549
35
359
0.97
0.02
1.4
1.8
3.74
3.52
mmol/l
0.45
22
265
10
93
1.08
0.02
1.3
1.5
1.23
1.33
mm
—
10
68
189
1881
1.01
0.01
7.2
6.6
0.18
0.19
e9/l
0.16
170
1653
40
406
0.98
0.00
1.5
1.4
—
—
—
0
0
10
98
1.02
0.00
1.4
1.6
—
—
—
0
0
10
102
0.98
0.00
1.1
1.2
—
—
—
0
0
11
112
0.98
0.00
27.5
9.5
—
—
—
0
0
11
112
0.98
0.00
2.0
2.9
—
—
—
0
0
27
272
0.99
0.00
1.1
1.3
58.08
145.87
u/ml
—
8
111
64
642
1.00
0.00
2.7
2.7
564.57
543.59
mosm/kgh2o
0.30
54
563
20
201
0.99
0.00
1.2
1.7
—
—
—
0
0
20
203
0.98
0.00
1.2
1.7
—
—
—
0
0
31
307
1.01
0.00
4.8
4.7
1.00
0.91
%
—
6
90
12
115
1.04
0.00
2.5
1.8
1.54
1.35
ug/l
0.06
12
103
20
204
0.98
0.00
1.2
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
6.2
—
7.10
—
0
5
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.0
—
1.08
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
139.00
—
0
6
8
85
0.94
-0.00
1.3
1.2
3.41
3.66
mmol/l
—
8
76
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
53.33
—
0
6
9
96
0.94
-0.00
1.2
1.3
465.11
463.76
mg/l
—
9
89
0
9
0.00
-0.00
0.0
3.1
—
8106.78
—
0
9
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
340
3400
1.00
-0.00
4.9
4.8
1.41
1.44
mmol/l
0.95
320
3212
0
8
0.00
-0.00
0.0
1.0
—
0.03
—
0
8
0
9
0.00
-0.00
0.0
1.8
—
1.20
—
0
9
9
94
0.96
-0.00
1.2
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
83
0.96
-0.00
1.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.5
—
10.17
—
0
6
0
9
0.00
-0.00
0.0
5.1
—
45.39
—
0
9
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
1.95
—
0
6
0
6
0.00
-0.00
0.0
2.2
—
3.17
—
0
6
0
8
0.00
-0.00
0.0
1.3
—
79.08
—
0
8
0
8
0.00
-0.00
0.0
1.0
—
53.31
—
0
8
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_BONE_SCAPULA_LONG_UPPER and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_BONE_SCAPULA_LONG_UPPER 1.04 [0.75, 1.44] 0.814
Birth year 0.993 [0.98, 1.0] 0.1

During the follow-up period (1.1.1998 — 31.12.2019), 53 out of 841 females with CD2_BENIGN_BONE_SCAPULA_LONG_UPPER died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_BONE_SCAPULA_LONG_UPPER 0.846 [0.65, 1.1] 0.217
Birth year 0.987 [0.98, 1.0] 0.007

During the follow-up period (1.1.1998 — 31.12.2019), 69 out of 986 males with CD2_BENIGN_BONE_SCAPULA_LONG_UPPER died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_BONE_SCAPULA_LONG_UPPER.

N-year risk Females Males
1 0.075% 0.198%
5 0.646% 1.007%
10 1.443% 2.695%
15 2.829% 5.179%
20 5.114% 8.344%

Relationships between endpoints

Index endpoint: CD2_BENIGN_BONE_SCAPULA_LONG_UPPER – Benign neoplasm: Scapula and long bones of upper limb

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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