This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
240 |
4. Check minimum number of eventsNone |
240 |
5. Include endpointsNone |
240 |
6. Filter based on genotype QC (FinnGen only) |
208 |
Control definitions (FinnGen only)
- Control exclude
- R18_GENERAL_SYMPTOMS_SIGNS
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- R[5-6]
- Name in latin
- Cachexia
Similar endpoints
↥List of similar endpoints to
Cachexia
based on the number of shared cases.
Similar with more cases:
- General symptoms and signs
- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 208 | 89 | 119 |
| Unadjusted period prevalence (%) | 0.04 | 0.03 | 0.05 |
| Median age at first event (years) | 74.67 | 72.81 | 76.06 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 217
- Matched controls
- 2170
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
R64
ICD-10 Finland
Cachexia
+∞
311.9
217
*
R63.4
ICD-10 Finland
Abnormal weight loss
19.4
43.7
36
22
R53
ICD-10 Finland
Malaise and fatigue
5.9
32.3
76
181
R50.9
ICD-10 Finland
Fever, unspecified
10.2
28.9
35
40
D64.9
ICD-10 Finland
Anaemia, unspecified
5.1
23.1
60
152
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.8
20.3
96
376
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.6
16.9
76
283
Z51.5
ICD-10 Finland
Palliative care
4.3
16.0
49
139
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.2
15.6
102
473
R55
ICD-10 Finland
Syncope and collapse
11.6
13.1
24
23
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.9
12.7
42
125
B03BA03
ATC
hydroxocobalamin; parenteral
5.0
12.6
29
65
JN4BD
NOMESCO Finland
Extensive body CT
3.9
11.6
38
112
R13
ICD-10 Finland
Dysphagia
4.5
11.1
29
72
JN4AD
NOMESCO Finland
Body CT examination
3.8
10.8
37
112
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.5
10.7
41
134
A04
ICPC
Weakness/tiredness general
3.3
10.7
47
168
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.6
10.4
121
717
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.9
9.6
56
235
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.4
9.0
93
514
E86
ICD-10 Finland
Volume depletion
8.8
8.8
18
22
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.2
8.6
38
135
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
4.6
8.6
21
49
A28
ICPC
Limited function/disability NOS
2.6
8.6
65
310
T08
ICPC
Weight loss
13.5
8.5
14
11
R18
ICD-10 Finland
Ascites
11.4
8.4
15
14
M05BX04
ATC
denosumab; parenteral
4.2
8.4
23
59
R4190
NOMESCO Finland
Nutritional therapy
7.7
8.1
18
25
M81.9
ICD-10 Finland
Osteoporosis, unspecified
4.4
7.7
20
49
R03BB04
ATC
tiotropium bromide; inhalant
2.8
7.5
41
165
N02AA05
ATC
oxycodone; systemic
2.5
7.5
57
271
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
16.5
7.3
11
7
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.6
7.3
47
206
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.0
7.2
36
137
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
3.6
7.2
25
76
WX302
NOMESCO Finland
Thoracal epidural anesthesy
4.1
7.2
20
52
AA1AD
NOMESCO Finland
CT of head and brain
2.3
7.0
71
381
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.7
6.9
40
165
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.8
6.9
22
63
A29
ICPC
General symptom/complaint other
2.8
6.8
38
154
R63.0
ICD-10 Finland
Anorexia
41.4
6.8
8
*
L28
ICPC
Limited function/disability (L)
2.4
6.5
52
251
A04AA01
ATC
ondansetron; systemic, rectal
3.4
6.5
24
76
R11
ICD-10 Finland
Nausea and vomiting
3.4
6.5
24
76
R56.8
ICD-10 Finland
Other and unspecified convulsions
71.9
6.5
7
*
130
Kela drug reimbursment
Malignant tumour
2.8
6.3
35
141
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
27.5
6.3
8
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
4.3
6.2
16
39
K08.3
ICD-10 Finland
Retained dental root
3.7
6.2
20
58
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.5
6.1
43
195
E87.6
ICD-10 Finland
Hypokalaemia
5.3
6.0
17
34
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
109
454
3.81
21.15
2.8
2.1
2.75
3.00
mg/l
0.65
95
389
142
724
3.78
19.83
8.2
4.5
31.65
35.07
g/l
6.69
135
668
68
214
4.17
19.59
6.5
5.0
1.00
1.03
mmol/l
0.33
62
197
27
40
7.57
17.85
1.7
1.2
254.88
315.82
ug/g
0.51
19
20
49
136
4.36
16.48
3.3
2.6
63.85
66.79
g/l
1.42
44
125
138
751
3.30
16.16
11.6
5.5
1.19
1.21
mmol/l
1.73
130
674
26
43
6.73
15.51
3.7
2.9
2.73
3.57
ratio
0.18
16
23
27
49
6.15
14.71
3.6
3.3
27.54
32.90
mg/l
0.53
20
42
27
49
6.15
14.71
3.7
3.3
54.17
174.24
mg/l
0.49
21
42
143
837
3.08
13.97
10.9
6.3
1.20
1.21
mmol/l
1.12
116
715
102
513
2.86
12.94
2.1
1.7
19.24
20.57
nmol/l
0.37
93
424
66
262
3.18
12.80
2.4
1.8
—
—
—
0
0
27
56
5.36
12.76
3.4
2.6
—
—
—
0
0
122
697
2.71
11.76
3.7
2.8
208.75
134.01
ug/l
2.23
114
632
34
96
4.01
10.99
5.5
6.9
25.24
24.06
mmol/l
0.58
34
96
48
172
3.30
10.89
2.8
2.4
7.15
9.43
umol/l
0.52
42
150
71
320
2.81
10.75
2.4
1.8
1302.23
1219.12
nmol/l
0.28
52
239
30
79
4.25
10.63
1.7
1.4
—
—
—
0
0
37
123
3.42
9.39
1.9
1.4
—
—
—
0
0
88
468
2.48
9.32
2.7
1.9
138.48
355.62
u/l
1.96
82
437
19
38
5.38
9.28
1.6
1.4
—
—
—
0
0
111
659
2.40
9.16
6.1
3.8
56.15
53.46
ng/l
0.07
97
517
136
884
2.44
9.13
13.0
7.7
5.11
4.31
e9/l
1.64
125
762
101
577
2.40
9.07
4.4
3.3
—
—
—
0
0
46
182
2.94
8.71
2.6
1.8
—
—
—
0
0
21
49
4.64
8.61
1.7
1.6
9.16
10.53
g/l
0.84
16
44
22
54
4.42
8.48
2.5
1.8
3.17
2.99
g/l
0.26
17
49
30
93
3.58
8.44
5.4
4.6
3.87
2.03
mmol/l
1.80
24
68
84
455
2.38
8.37
3.7
3.3
0.96
0.49
e6/l
0.63
70
338
47
193
2.83
8.29
2.6
1.8
—
—
—
0
0
23
60
4.17
8.21
2.4
1.7
7.61
7.83
g/l
0.25
18
55
23
60
4.17
8.21
2.4
1.7
3.72
3.53
g/l
0.27
18
55
23
60
4.17
8.21
2.4
1.7
4.08
4.30
g/l
0.41
18
55
21
51
4.45
8.20
1.3
1.1
—
—
—
0
0
48
203
2.75
7.99
9.9
6.5
0.79
0.77
mmol/l
0.01
32
166
19
44
4.64
7.85
4.2
2.7
7.26
8.14
kpa
1.15
19
44
111
697
2.21
7.60
3.5
2.4
79.52
80.95
nmol/l
0.17
98
606
118
764
2.19
7.43
2.7
2.2
83.94
95.20
pmol/l
1.84
68
395
150
1070
2.30
7.41
6.9
4.5
14.60
2385.33
e6/l
—
5
27
39
157
2.81
7.09
4.5
3.4
4.35
1.43
mmol/l
2.41
30
129
18
34
5.67
6.63
1.9
1.4
—
—
—
0
0
49
232
2.44
6.40
10.4
6.0
104.29
104.89
mmol/l
0.29
49
232
45
206
2.49
6.31
10.2
6.5
4.79
5.09
kpa
1.55
40
198
31
117
2.92
6.31
5.4
4.1
5.33
5.18
kpa
0.44
31
112
27
94
3.14
6.31
2.3
1.7
—
—
—
0
0
45
207
2.48
6.25
10.2
6.5
11.31
11.83
kpa
0.34
40
199
53
264
2.33
6.17
2.9
3.1
1.26
1.28
e6/l
0.01
32
142
19
54
3.76
6.03
1.8
2.2
0.09
1.08
g/l
0.98
14
44
11
14
8.21
5.41
1.2
1.5
—
—
—
0
0
88
558
1.97
5.40
4.0
3.3
2.32
2.35
mmol/l
0.95
82
504
15
30
5.29
5.36
1.5
1.2
—
—
—
0
0
29
118
2.68
5.13
1.8
2.0
1.92
1.58
%
0.90
24
108
15
32
4.96
5.10
1.5
1.2
—
—
—
0
0
41
200
2.29
4.95
3.8
4.8
769.31
11.32
ug/l
0.50
35
168
124
899
1.89
4.94
4.9
2.9
64.37
47.29
u/l
1.10
118
827
14
30
4.91
4.77
7.6
3.6
5.01
5.08
kpa
0.08
14
30
50
269
2.12
4.75
2.2
1.8
29.37
28.76
s
0.46
50
262
66
394
1.97
4.72
3.1
2.5
—
—
—
0
0
88
581
1.87
4.63
3.8
3.4
5275.96
1948.33
ng/l
1.75
78
500
13
27
5.05
4.58
1.3
1.1
—
—
—
0
0
15
44
3.59
4.55
5.3
2.8
1.81
2.70
index
—
10
27
30
132
2.48
4.54
3.4
2.0
34.84
28.76
u/l
0.43
25
110
10
15
6.93
4.52
1.7
1.3
—
—
—
0
0
46
251
2.06
4.18
3.7
3.1
1.86
1.39
e6/l
0.32
25
129
51
290
1.99
4.14
1.4
1.2
0.91
0.81
u/ml
0.23
14
65
17
58
3.10
4.11
5.8
5.4
26.47
25.61
mmol/l
0.52
17
52
146
1155
1.81
4.00
5.5
3.9
19.79
13.40
mm/h
3.99
138
1068
103
742
1.74
3.88
4.0
2.9
—
—
estimate
—
0
0
10
19
5.46
3.87
1.3
1.2
—
—
—
0
0
10
20
5.19
3.73
1.3
1.3
385.70
649.75
mg/l
—
10
20
58
362
1.82
3.52
4.8
2.9
2.47
2.46
mmol/l
0.17
53
319
6
6
10.23
3.52
1.0
1.2
93.67
86.00
pmol/l
—
6
6
112
846
1.67
3.41
5.4
3.9
0.18
10.04
estimate
0.48
28
187
11
28
4.08
3.34
3.0
3.4
8.83
9.61
pmol/l
0.08
11
28
71
480
1.71
3.25
5.8
4.1
0.00
0.00
estimate
-0.00
24
158
10
24
4.32
3.23
1.4
1.1
—
—
—
0
0
110
836
1.64
3.20
5.5
3.9
0.00
0.00
estimate
-0.00
27
172
112
857
1.63
3.16
5.4
3.9
0.00
0.00
estimate
-0.00
27
169
7
12
5.99
3.04
1.6
1.2
—
—
—
0
0
30
157
2.06
3.03
2.1
2.3
4.27
7.48
ug/l
1.89
25
137
38
613
0.54
3.02
1.7
1.9
1.05
1.28
mmol/l
2.07
30
502
141
1152
1.64
2.98
4.7
3.8
15.32
14.99
pmol/l
0.78
128
1009
16
64
2.62
2.94
1.6
1.7
—
—
—
0
0
31
169
1.97
2.81
5.6
3.1
—
—
—
0
0
50
318
1.74
2.81
4.6
3.4
503.98
443.96
ng/l
0.07
43
272
16
66
2.54
2.78
5.3
2.6
26.14
24.85
mmol/l
0.53
16
66
11
34
3.35
2.77
1.5
1.5
—
—
—
0
0
6
10
6.13
2.71
6.3
4.1
350.50
290.90
umol/l
—
6
10
6
10
6.13
2.71
1.8
1.0
—
—
—
0
0
6
11
5.57
2.56
1.5
1.5
—
—
—
0
0
6
11
5.57
2.56
1.5
1.5
—
—
—
0
0
174
1526
1.71
2.54
37.6
14.4
31.39
27.67
mg/l
0.94
165
1266
6
12
5.11
2.42
1.5
1.2
—
—
—
0
0
6
12
5.11
2.42
1.5
1.2
—
—
—
0
0
6
12
5.11
2.42
1.3
1.2
—
—
—
0
0
6
12
5.11
2.42
1.5
1.2
—
—
—
0
0
8
23
3.57
2.29
1.5
1.1
—
—
—
0
0
8
23
3.57
2.29
1.1
1.4
—
—
—
0
0
7
18
3.98
2.27
1.6
1.1
—
—
—
0
0
7
18
3.98
2.27
1.0
1.2
—
—
—
0
0
94
735
1.49
2.17
2.9
2.5
—
—
—
0
0
53
366
1.59
2.15
2.4
1.9
490.56
18750434.71
pmol/l
0.50
45
304
10
37
2.78
2.10
1.4
1.5
—
—
—
0
0
47
321
1.59
2.00
1.4
1.5
1.66
1.45
mg/l
0.28
41
260
13
59
2.28
1.88
1.2
1.6
—
—
—
0
0
5
12
4.24
1.83
1.4
1.1
—
—
—
0
0
5
12
4.24
1.83
1.4
1.1
—
—
—
0
0
5
12
4.24
1.83
1.4
1.1
—
—
—
0
0
5
12
4.24
1.83
1.4
1.1
—
—
—
0
0
5
13
3.91
1.72
1.4
1.1
—
—
—
0
0
5
13
3.91
1.72
1.4
1.1
—
—
—
0
0
16
83
2.00
1.69
1.3
1.1
574.55
86.82
u/ml
0.75
16
78
6
19
3.22
1.67
5.0
1.5
1658.33
799.89
mg
—
6
19
6
21
2.91
1.51
2.8
3.8
—
—
—
0
0
174
1588
1.48
1.51
43.2
19.1
138.16
139.84
mmol/l
10.04
168
1549
9
37
2.49
1.50
1.6
1.1
—
—
—
0
0
174
1590
1.48
1.48
43.1
19.2
3.99
4.01
mmol/l
0.34
168
1548
155
1403
1.37
1.26
6.0
4.9
2.08
2.00
mu/l
0.16
142
1247
22
140
1.64
1.26
3.5
2.5
0.37
0.65
e6/l
0.36
22
134
78
639
1.34
1.25
6.2
3.9
0.00
0.04
estimate
0.96
25
148
11
57
1.98
1.19
1.5
1.9
36.09
40.09
u/l
0.25
11
49
136
1494
0.76
1.13
4.2
5.1
1.53
1.45
mmol/l
1.04
127
1361
141
1541
0.76
1.13
4.6
6.1
2.17
2.53
mmol/l
6.08
131
1412
5
21
2.41
1.09
1.4
1.8
—
—
—
0
0
138
1506
0.77
1.04
4.2
5.2
4.17
4.43
mmol/l
2.37
129
1389
27
369
0.69
0.98
3.4
3.5
0.89
0.83
ug/l
0.12
22
250
13
77
1.73
0.97
1.0
1.2
195.60
161.46
u/ml
—
5
25
177
1660
1.36
0.97
51.4
23.6
257.77
240.97
e9/l
1.92
172
1621
56
453
1.32
0.96
5.0
3.5
9.26
0.01
estimate
0.49
27
137
177
1661
1.36
0.95
52.2
23.9
36.12
39.81
%
15.50
172
1632
177
1661
1.36
0.95
51.3
23.5
93.62
91.39
fl
5.59
172
1632
177
1661
1.36
0.95
51.4
23.5
3.96
4.44
e12/l
21.65
172
1611
7
37
1.92
0.95
1.0
1.2
—
—
—
0
0
177
1662
1.35
0.94
52.0
23.7
119.44
133.53
g/l
23.45
172
1632
6
27
2.26
0.94
1.0
1.5
—
—
—
0
0
6
27
2.26
0.94
1.0
1.5
—
—
—
0
0
49
604
0.76
0.94
3.9
4.1
36.53
11.16
mg/mmol
0.99
29
389
50
401
1.32
0.91
3.0
2.6
337.09
362.21
umol/l
0.76
45
348
6
31
1.96
0.85
1.2
1.2
—
—
—
0
0
48
388
1.30
0.83
6.1
4.1
1.02
1.02
kg/l
0.36
33
260
158
1471
1.27
0.82
34.7
15.3
74.24
72.99
ml/min/173m2
0.27
151
1365
7
41
1.73
0.70
1.6
1.2
—
—
—
0
0
7
42
1.69
0.69
1.0
1.1
—
—
—
0
0
5
27
1.87
0.69
1.2
1.1
0.57
0.90
nmol/l
—
5
22
7
43
1.65
0.67
1.0
1.1
—
—
—
0
0
43
515
0.79
0.65
4.4
5.0
22.68
21.70
%
0.13
24
270
5
29
1.74
0.64
1.0
1.2
—
2.12
—
0
6
5
29
1.74
0.64
1.2
1.6
—
—
—
0
0
19
139
1.40
0.63
3.1
3.0
579.60
181.15
ng/l
1.22
19
130
134
1432
0.83
0.62
3.8
4.4
1.06
1.25
mmol/l
4.44
122
1293
138
1464
0.84
0.55
5.5
6.9
38.41
40.06
mmol/mol
1.12
125
1367
11
74
1.51
0.54
1.1
1.1
—
—
—
0
0
21
164
1.31
0.49
1.2
1.5
—
—
—
0
0
16
121
1.35
0.45
1.8
3.3
65.75
58.67
ml/min/173m2
—
8
51
0
16
0.00
0.41
0.0
1.1
—
1.29
—
0
7
5
35
1.44
0.39
1.4
1.6
—
—
—
0
0
6
41
1.48
0.36
2.8
2.0
—
—
—
0
0
6
42
1.44
0.36
1.5
1.5
100.67
87.29
%
—
6
42
26
230
1.15
0.22
1.1
1.2
42.36
11.91
u/ml
—
7
88
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
11
90
1.23
0.19
2.0
1.8
—
—
—
0
0
14
119
1.19
0.18
1.5
2.4
13.38
12.37
nmol/l
—
9
106
7
62
1.13
0.17
1.0
1.2
—
—
—
0
0
10
83
1.21
0.15
2.1
1.8
—
—
—
0
0
10
117
0.85
0.13
1.7
1.4
—
—
—
0
0
62
646
0.94
0.11
5.2
6.2
1.91
3.00
ug/l
1.22
57
570
153
1504
1.06
0.11
4.7
5.5
6.01
6.04
mmol/l
0.05
138
1361
5
45
1.11
0.10
3.4
1.5
—
—
—
0
0
19
200
0.95
0.04
12.1
7.4
—
—
—
0
0
26
251
1.04
0.03
1.3
1.2
37.00
45.65
iu/ml
—
8
84
17
170
1.00
-0.00
1.4
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
604.60
—
0
5
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
6
0.00
-0.00
0.0
1.2
—
114.33
—
0
6
0
9
0.00
-0.00
0.0
2.4
—
7.31
—
0
9
0
6
0.00
-0.00
0.0
1.0
—
5.66
—
0
6
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
0
8
0.00
-0.00
0.0
1.0
—
133.50
—
0
8
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.7
—
72.29
—
0
7
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: R18_CACHEXIA – Cachexia
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).