Purulent endophthalmitis

H7_PURENDOPHTHALMITIS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H44.0
  • Hospital discharge: ICD-9 3600A
  • Hospital discharge: ICD-8 3660[0-1]
  • Cause of death: ICD-10 H44.0
  • Cause of death: ICD-9 3600A
  • Cause of death: ICD-8 3660[0-1]

2 out of 7 registries used, show all original rules.

267

4. Check minimum number of events

None

267

5. Include endpoints

None

267

6. Filter based on genotype QC (FinnGen only)

241

Control definitions (FinnGen only)

Control exclude
H7_VITREOUS

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF6
Parent code in ICD-10
H44
Name in latin
Endophthalmitis purulenta

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1886 976 889
Only index persons 1367 724 643
Unadjusted period prevalence (%)
Whole population 0.03 0.03 0.02
Only index persons 0.03 0.03 0.02
Median age at first event (years)
Whole population 70.38 74.48 66.01
Only index persons 69.64 74.44 64.23

-FinnGen-

Key figures

All Female Male
Number of individuals 241 119 122
Unadjusted period prevalence (%) 0.05 0.04 0.06
Median age at first event (years) 72.73 74.18 71.30

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
248
Matched controls
2480
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H44.0
ICD-10 Finland
Purulent endophthalmitis
+∞
291.8
219
*
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
48.8
219.1
160
89
CKA10
NOMESCO Finland
Biopsy of vitreous body
+∞
141.6
122
*
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
52.7
128.5
77
21
WX140
NOMESCO Finland
Parabulbar anesthesy
26.0
128.3
104
67
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
41.2
75.3
47
14
H44.1
ICD-10 Finland
Other endophthalmitis
+∞
61.0
56
*
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
11.5
59.9
73
87
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
8.5
56.4
95
168
H33.0
ICD-10 Finland
Retinal detachment with retinal break
17.0
49.7
44
31
Z96.1
ICD-10 Finland
Presence of intraocular lens
6.4
47.2
122
325
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
13.5
42.5
43
38
XCW99
NOMESCO Finland
Other investigative procedure of eye
6.9
40.3
78
155
S01ED51
ATC
timolol, combinations; ophthalmic
6.9
37.9
71
136
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
5.1
32.8
172
767
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
7.6
32.3
52
84
H43.1
ICD-10 Finland
Vitreous haemorrhage
+∞
30.9
29
*
TCH12
NOMESCO Finland
Sample aspiration from anterior chambre
+∞
28.7
27
*
S01ED01
ATC
timolol; ophthalmic
8.3
28.0
40
56
WX100
NOMESCO Finland
Conjunctival surface anesthesia
4.6
27.1
88
267
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
50.3
26.2
31
7
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
7.1
24.5
40
65
S01EC01
ATC
acetazolamide; systemic
10.1
23.4
28
31
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
3.9
22.8
168
873
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.0
22.3
86
291
H16.0
ICD-10 Finland
Corneal ulcer
7.8
22.2
33
48
3600A
ICD-9 Finland
Disorders of the globe, Purulent endophthalmitis
+∞
20.1
19
*
S01EA05
ATC
brimonidine; ophthalmic
9.2
19.6
25
30
WX142
NOMESCO Finland
Sub-tenon anesthesy
50.5
19.6
23
5
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
3.4
19.0
161
875
114
Kela drug reimbursment
Glaucoma
4.2
19.0
62
184
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
21.2
17.3
25
13
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
22.0
16.8
24
12
H25.1
ICD-10 Finland
Senile nuclear cataract
3.1
16.7
143
764
H26.4
ICD-10 Finland
After-cataract
3.7
16.6
63
207
XCK10
NOMESCO Finland
Photography of fundus of eye
3.9
16.4
58
181
S01EE01
ATC
latanoprost; ophthalmic
4.4
15.9
45
119
CKC12
NOMESCO Finland
Photocoagulation of retina
6.8
15.8
26
42
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
40.9
15.6
19
5
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
6.7
14.5
24
39
S01EA03
ATC
apraclonidine; ophthalmic
24.0
14.5
20
9
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
25.6
14.0
19
8
XCK00
NOMESCO Finland
Perimetry
4.4
13.5
37
95
S01EC04
ATC
brinzolamide; ophthalmic
5.0
13.5
31
69
CJB10
NOMESCO Finland
Laser discission of secondary cataract
3.5
13.2
52
173
H20.1
ICD-10 Finland
Chronic iridocyclitis
52.9
13.0
15
*
H43.8
ICD-10 Finland
Other disorders of vitreous body
14.2
12.7
21
16
H02AB06
ATC
prednisolone; systemic
2.7
12.7
151
913
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
136.6
12.6
13
*
H26.2
ICD-10 Finland
Complicated cataract
28.3
12.2
16
6
WX002
NOMESCO Finland
Sedation and analgesia
2.9
12.1
76
332
XCH00
NOMESCO Finland
Eye pressure measurement
4.8
12.1
29
67
S01EE05
ATC
tafluprost; ophthalmic
5.2
12.0
26
55
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
4.2
11.3
32
84
ZX198
NOMESCO Finland
Other local administration
21.3
11.3
16
8
WX704
NOMESCO Finland
Intubation
4.5
11.2
29
71
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
62.8
10.7
12
*
H33.5
ICD-10 Finland
Other retinal detachments
62.8
10.7
12
*
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
11.3
10.5
19
18
S01EC54
ATC
brinzolamide, combinations; ophthalmic
11.3
10.5
19
18
ZXA00
NOMESCO Finland
Right side
2.5
10.4
96
503
H16.9
ICD-10 Finland
Keratitis, unspecified
15.4
10.1
16
11
CKD40
NOMESCO Finland
Endophotocoagulation of retina
12.9
10.0
17
14
H40.0
ICD-10 Finland
Glaucoma suspect
3.5
9.8
37
119
XCD10
NOMESCO Finland
Electrophysiological examination of eye
5.6
9.8
19
36
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
10.7
9.7
18
18
S01BC03
ATC
diclofenac; ophthalmic
10.7
9.7
18
18
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
5.5
9.5
19
37
H35.36
ICD-10 Finland
Macular cyst
31.4
9.5
12
*
3643
FHL
Vitrectomy through pars Plana
38.2
9.1
11
*
ZXD05
NOMESCO Finland
Urgent procedure
2.3
9.0
92
499
ZXA10
NOMESCO Finland
Bilateral
2.5
8.8
72
353
S01BA01
ATC
dexamethasone; ophthalmic
4.9
8.8
20
44
CHC05
NOMESCO Finland
Iridotomy
9.5
8.7
17
19
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
3.2
8.5
37
130
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
93.1
8.5
9
*
TCK20
NOMESCO Finland
Needle biopsy of vitreous body
+∞
8.4
8
*
CM2X4
NOMESCO Finland
Follow-up OCT of age-related macular degeneration lesions
15.2
8.3
13
9
CM2S4
NOMESCO Finland
Follow-up photography of age-related macular degeneration lesions
22.9
8.1
11
5
S01AX11
ATC
[U] ofloxacin
4.7
8.0
19
43
H57.1
ICD-10 Finland
Ocular pain
4.9
8.0
18
39
H34.8
ICD-10 Finland
Other retinal vascular occlusions
6.8
7.9
19
30
S01BA04
ATC
prednisolone; ophthalmic
7.1
7.7
18
27
A10AA02, ,
ATC
4.4
7.7
20
49
Z94.7
ICD-10 Finland
Corneal transplant status
25.9
7.6
10
*
ZXA05
NOMESCO Finland
Left side
2.2
7.3
79
432
36600
ICD-8 Finland
Other inflammation of uveal tract, Abscessus oculi. Uveitis suppurativa. Panophthalmitis
+∞
7.3
7
*
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
16.4
7.3
11
7
TPH07
NOMESCO Finland
Cathetrisation of artery
2.7
7.2
42
173
H40.9
ICD-10 Finland
Glaucoma, unspecified
6.4
7.2
18
30
CKD15
NOMESCO Finland
Injection of vitreous substitute
31.0
7.2
9
*
CHD65
NOMESCO Finland
Nonpenetrating glaucoma surgery
20.7
7.2
10
5
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
7.9
7.0
15
20
TPH04
NOMESCO Finland
Cathetrisation of vein
2.2
6.9
69
365
H3603, E103,
ICD-10 Finland
41.2
6.8
8
*
H20.8
ICD-10 Finland
Other iridocyclitis
41.2
6.8
8
*
XCD20
NOMESCO Finland
Photoangiography of eye
7.2
6.6
15
22
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
71.6
6.5
7
*
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
14.8
6.4
10
7
H40.11
ICD-10 Finland
Low pressure glaucoma
5.8
6.4
17
31
127
Kela drug reimbursment
Transplant complication
18.6
6.3
9
5
S01EE03
ATC
bimatoprost; ophthalmic
5.6
6.3
17
32
H44.5
ICD-10 Finland
Degenerated conditions of globe
+∞
6.3
6
*
3626
FHL
Extracapsular cataract surgery and implantation of an artificial lens
6.6
6.3
15
24
H19.1*B00.5
ICD-10 Finland
Herpesviral keratoconjunctivitis
13.0
6.1
10
8
Z3229
NOMESCO Finland
Other healthcare associate professional
2.7
6.1
34
137
J01MA12
ATC
levofloxacin; systemic
2.2
6.1
62
329

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
146
323
9.56
72.94
2.6
2.0
—
—
—
0
0
107
261
6.45
45.29
1.9
1.4
—
—
—
0
0
67
263
3.12
13.05
2.2
1.7
—
—
—
0
0
65
294
2.64
9.46
5.8
6.3
7.42
7.42
ph
0.36
35
184
61
287
2.49
8.08
5.9
6.4
1.20
1.15
mmol/l
0.02
45
237
110
692
2.06
7.05
6.0
4.3
—
—
—
0
0
110
732
1.90
5.69
8.0
5.6
—
—
—
0
0
144
1071
1.82
5.02
6.8
5.9
0.62
0.62
e9/l
0.08
123
907
16
46
3.65
4.98
1.1
1.1
—
—
—
0
0
47
241
2.17
4.97
2.1
1.7
—
—
—
0
0
144
1074
1.81
4.95
6.8
5.9
0.04
0.04
e9/l
0.69
123
911
146
1106
1.78
4.64
5.3
4.4
0.00
0.00
estimate
-0.00
34
251
147
1117
1.78
4.61
5.5
4.4
0.00
6.22
estimate
0.50
35
261
145
1100
1.77
4.55
7.4
6.2
0.19
0.20
e9/l
0.31
126
941
8
8
10.28
4.55
1.1
1.3
585.38
1116.75
u/ml
—
8
8
135
1004
1.76
4.54
7.4
6.3
26.57
25.77
%
0.28
127
947
155
1200
1.78
4.52
9.9
9.4
4.39
4.29
e9/l
0.18
134
1039
10
15
6.89
4.51
1.0
1.3
—
—
—
0
0
133
986
1.75
4.51
7.8
6.2
0.66
0.64
%
0.13
125
920
133
988
1.75
4.46
7.9
6.3
8.53
9.10
%
1.71
125
923
144
1094
1.75
4.46
6.9
6.0
2.05
1.78
e9/l
0.68
125
952
133
989
1.74
4.44
7.7
6.1
2.81
2.84
%
0.04
125
922
108
758
1.75
4.42
4.7
4.1
25.53
8.82
mg/mmol
0.93
74
484
147
1129
1.74
4.33
5.6
4.5
0.00
1.27
estimate
0.51
31
239
152
1183
1.74
4.23
12.2
7.0
1.19
1.21
mmol/l
2.20
130
1023
107
757
1.73
4.20
4.6
3.7
—
—
—
0
0
10
17
6.08
4.17
2.0
2.4
—
—
—
0
0
121
889
1.71
4.12
4.1
4.0
6.25
6.25
ph
0.02
59
494
47
259
2.01
4.09
9.0
3.7
1.34
2.02
mmol/l
0.58
39
214
8
10
8.22
4.09
1.0
1.1
—
—
—
0
0
48
267
1.99
4.07
9.3
3.7
7.37
7.38
ph
0.79
30
166
138
1068
1.66
3.73
9.8
6.1
1.19
1.21
mmol/l
2.84
128
977
130
992
1.65
3.70
7.3
6.1
58.64
58.95
%
0.09
123
942
104
751
1.66
3.67
4.0
3.3
6.88
7.32
mmol/l
0.41
93
621
72
472
1.74
3.62
5.4
4.7
1.02
1.02
kg/l
0.19
56
315
95
672
1.67
3.61
4.1
2.5
53.58
63.88
u/l
0.76
90
626
39
211
2.01
3.57
12.2
7.8
—
—
—
0
0
102
741
1.64
3.47
4.1
3.3
76.94
50.51
mg/l
0.31
73
488
90
640
1.64
3.30
5.1
4.6
0.00
0.01
estimate
0.50
30
230
6
7
8.74
3.28
1.2
1.0
2470.17
1396.57
miu/ml
—
6
7
93
669
1.62
3.25
3.9
2.6
—
—
—
0
0
111
840
1.58
3.11
6.3
4.3
132.02
115.82
e6/l
0.13
74
613
6
8
7.65
3.07
1.0
1.0
—
—
—
0
0
118
908
1.57
3.06
16.0
13.5
0.00
0.00
e9/l
0.43
94
749
140
1124
1.56
2.99
15.9
16.4
1.29
1.31
inr
0.12
117
946
119
926
1.55
2.89
3.7
3.0
—
—
estimate
—
0
0
57
372
1.69
2.86
4.9
3.4
1.21
2.25
e6/l
1.04
29
189
101
760
1.55
2.84
5.2
3.7
50.56
125.32
e6/l
0.42
75
593
130
1041
1.52
2.71
7.1
4.5
33.92
34.91
g/l
1.14
120
967
169
1437
1.55
2.63
6.8
5.0
—
2.61
—
0
5
98
744
1.52
2.60
7.3
4.2
7.40
7.40
ph
0.20
72
529
89
662
1.54
2.59
5.1
3.5
0.45
0.41
e6/l
0.06
65
502
33
189
1.86
2.57
4.5
4.3
0.87
0.54
%
0.25
15
67
29
160
1.92
2.52
4.1
3.5
—
—
—
0
0
12
45
2.75
2.49
3.8
2.6
11.84
10.27
pmol/l
0.17
12
45
38
230
1.77
2.48
8.4
3.0
4.45
4.17
kpa
0.38
38
223
108
845
1.49
2.45
5.2
4.5
0.00
0.03
estimate
1.05
26
208
35
209
1.79
2.39
4.3
4.3
0.69
0.87
%
0.30
16
78
33
195
1.80
2.34
4.3
4.4
0.23
0.11
%
0.44
13
64
184
1613
1.55
2.33
10.1
7.9
82.03
81.51
u/l
0.05
177
1510
172
1488
1.51
2.30
5.5
4.3
15.14
15.14
pmol/l
0.01
150
1312
23
121
1.99
2.29
1.8
1.5
—
—
—
0
0
16
74
2.24
2.20
1.4
1.7
—
—
—
0
0
177
1551
1.49
2.14
37.9
24.0
13.85
13.90
%
0.17
177
1537
9
32
2.88
2.02
2.4
1.4
—
—
—
0
0
198
1786
1.54
1.98
6.9
5.5
2.21
2.02
mu/l
1.02
180
1598
33
206
1.69
1.95
2.2
1.5
—
—
—
0
0
5
11
4.61
1.95
2.0
1.4
1487.80
1623.18
ml
—
5
11
18
93
2.01
1.90
2.7
2.1
0.00
0.00
estimate
—
6
31
11
46
2.46
1.88
1.8
2.9
25.55
34.23
umol/l
1.42
11
39
29
179
1.70
1.79
2.4
1.6
—
—
—
0
0
32
205
1.64
1.73
4.6
4.7
0.08
0.22
%
0.38
12
65
80
625
1.41
1.72
2.6
2.3
2.79
3.15
mg/l
0.55
74
538
34
223
1.61
1.68
3.5
3.1
66.33
66.32
g/l
0.00
27
202
37
248
1.58
1.68
2.9
2.8
54.50
69.27
e9/l
2.26
28
195
169
1499
1.40
1.67
37.8
25.2
332.49
331.24
g/l
1.02
169
1493
65
495
1.42
1.60
1.2
1.4
—
—
—
0
0
6
20
3.05
1.59
2.0
1.2
9.67
10.86
%
—
6
20
63
479
1.42
1.56
4.0
3.3
508.76
522.74
mosm/kgh2o
0.21
58
417
208
1925
1.50
1.55
29.1
18.6
29.51
25.14
mg/l
1.01
187
1634
207
1914
1.49
1.55
7.3
6.3
2.35
2.54
mmol/l
2.45
190
1732
31
204
1.59
1.52
4.0
2.4
31.12
34.46
u/l
0.34
26
169
202
1861
1.46
1.52
6.4
5.7
6.59
6.11
mmol/l
1.86
184
1667
17
94
1.87
1.51
3.9
1.8
1054.00
326.53
ug/l
0.67
17
89
214
1996
1.53
1.49
36.1
22.8
139.29
139.54
mmol/l
0.63
214
1948
214
1996
1.53
1.49
36.6
23.0
4.03
4.00
mmol/l
0.85
214
1946
72
566
1.38
1.47
3.2
3.0
377.67
358.62
umol/l
0.56
60
485
9
39
2.36
1.44
1.3
1.3
—
—
—
0
0
89
727
1.35
1.43
2.6
2.1
193.32
211.40
u/l
0.16
84
689
202
1871
1.43
1.38
6.3
5.4
4.25
4.45
mmol/l
1.90
184
1697
31
210
1.54
1.36
2.6
2.5
8.98
5.15
ug/l
0.76
24
182
11
54
2.09
1.35
4.7
3.6
—
—
—
0
0
9
43
2.13
1.31
3.4
3.1
3.35
4.53
e9/l
—
9
43
95
792
1.32
1.31
2.0
2.0
1.28
1.29
mmol/l
0.04
80
645
209
1954
1.44
1.29
26.8
17.1
—
—
—
0
0
17
100
1.75
1.27
1.1
1.3
—
—
—
0
0
25
164
1.58
1.26
1.3
1.6
—
—
—
0
0
8
36
2.26
1.25
1.3
1.4
—
—
—
0
0
6
25
2.43
1.25
6.3
4.0
—
—
—
0
0
79
646
1.33
1.24
8.8
5.8
—
—
—
0
0
75
609
1.33
1.23
5.4
3.9
0.00
0.12
estimate
0.50
23
205
28
190
1.53
1.23
8.6
4.1
1.21
1.22
mmol/l
0.24
19
164
57
444
1.37
1.23
5.9
5.6
—
—
—
0
0
200
1861
1.39
1.22
6.2
5.3
1.43
1.45
mmol/l
0.33
181
1681
5
19
2.66
1.22
1.0
1.4
—
—
—
0
0
6
26
2.34
1.19
2.0
1.3
287.17
263.41
mosm/kgh2o
—
6
17
5
20
2.53
1.15
3.0
1.1
—
—
—
0
0
13
73
1.82
1.13
5.2
2.0
1.69
1.71
mg/l
0.03
13
60
198
1853
1.34
1.05
9.7
7.2
43.43
40.45
mmol/mol
2.76
185
1707
11
60
1.87
1.04
2.5
2.3
370.07
85.65
ug/min
—
6
35
7
34
2.09
1.03
1.3
1.1
—
—
—
0
0
212
2008
1.38
1.01
16.0
12.7
26.63
24.24
u/l
0.39
205
1937
190
1777
1.30
0.95
5.3
4.5
1.30
1.26
mmol/l
0.34
170
1586
7
37
1.92
0.95
2.4
1.2
—
—
—
0
0
6
29
2.09
0.90
1.7
1.3
—
—
—
0
0
15
96
1.60
0.86
3.1
3.4
—
—
—
0
0
57
469
1.28
0.85
1.9
1.7
1.25
1.63
mg/l
0.72
43
380
213
2033
1.34
0.83
37.6
25.2
95.90
83.40
umol/l
1.84
213
2003
214
2046
1.34
0.81
42.8
28.5
92.20
91.65
fl
1.14
214
2016
16
106
1.54
0.81
2.9
2.7
—
—
—
0
0
214
2047
1.33
0.80
42.8
28.5
30.63
30.41
pg
1.39
214
2017
214
2047
1.33
0.80
43.0
28.6
242.23
239.27
e9/l
0.25
214
2004
214
2047
1.33
0.80
43.4
28.8
130.94
132.72
g/l
0.84
214
2017
214
2047
1.33
0.80
43.6
29.0
38.93
39.72
%
1.04
214
2017
6
33
1.84
0.79
1.0
1.4
—
—
—
0
0
6
33
1.84
0.79
1.0
1.4
—
—
—
0
0
6
33
1.84
0.79
1.0
1.4
—
—
—
0
0
6
33
1.84
0.79
1.0
1.4
—
—
—
0
0
26
192
1.40
0.79
8.9
3.7
142.34
88.61
ng/l
0.84
20
162
90
788
1.22
0.78
3.1
3.1
2.31
2.35
mmol/l
2.19
81
699
32
247
1.34
0.75
4.4
2.9
4.05
5.43
e9/l
0.70
27
206
115
1035
1.21
0.75
2.5
2.2
100.08
95.72
pmol/l
0.43
62
530
101
898
1.21
0.74
4.5
3.1
148.40
142.41
ug/l
0.13
93
816
7
38
1.87
0.74
2.6
1.7
31.71
32.82
pg
—
7
38
10
60
1.69
0.73
3.2
2.9
55.91
61.46
%
—
10
60
5
25
2.02
0.73
1.0
4.2
14.46
16.14
%
—
5
25
83
727
1.21
0.71
2.0
1.8
20.82
20.77
nmol/l
0.01
75
597
59
500
1.24
0.69
2.4
2.9
2.43
2.46
mmol/l
1.33
54
446
5
27
1.87
0.69
1.0
4.1
8.12
7.80
mmol/l
—
5
27
132
1211
1.19
0.68
3.8
3.3
43.54
51.77
u/l
1.00
124
1118
104
936
1.19
0.66
6.0
4.5
64.38
43.37
ng/l
0.74
80
748
14
96
1.49
0.63
2.4
2.8
10.67
2508.35
u/ml
—
9
84
10
63
1.61
0.62
1.0
1.8
—
—
—
0
0
5
30
1.68
0.61
1.0
1.1
—
—
—
0
0
12
80
1.53
0.61
1.2
1.4
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
1.47
—
0
11
0
21
0.00
0.60
0.0
3.5
—
3.31
—
0
21
0
22
0.00
0.59
0.0
1.3
—
—
—
0
0
31
249
1.28
0.57
4.8
4.0
3.57
54.54
ug/l
0.94
21
204
13
90
1.47
0.56
4.1
3.0
625.14
320.71
mg/l
—
7
35
9
60
1.52
0.55
14.6
14.9
—
—
—
0
0
9
61
1.49
0.54
1.0
1.1
—
—
—
0
0
13
91
1.45
0.54
2.6
3.7
1.14
3.66
ratio
—
5
47
27
215
1.29
0.53
2.3
2.4
175.83
177.09
ug/g
0.00
18
174
15
109
1.40
0.52
2.9
2.5
—
—
—
0
0
6
40
1.51
0.52
1.5
1.4
295.00
189.41
pmol/l
—
6
40
14
101
1.41
0.50
2.8
2.1
—
—
—
0
0
47
407
1.19
0.46
1.4
1.5
2.96
2.77
g/l
0.27
30
232
5
32
1.57
0.42
2.4
2.2
84.46
88.97
%
—
5
32
5
33
1.53
0.41
1.6
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
1.50
—
0
6
0
17
0.00
0.41
0.0
2.6
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
3.75
—
0
8
8
61
1.32
0.40
1.0
1.2
—
—
—
0
0
22
268
0.80
0.39
1.1
1.3
—
—
—
0
0
24
199
1.23
0.36
2.5
2.5
—
—
—
0
0
6
47
1.28
0.32
1.3
1.2
21.66
23.66
u/l
—
6
40
13
101
1.30
0.32
1.5
1.3
—
—
—
0
0
19
158
1.22
0.29
1.1
1.2
—
—
—
0
0
8
63
1.28
0.28
3.5
3.5
0.79
0.87
nmol/l
—
8
55
84
786
1.10
0.28
2.1
2.3
—
—
—
0
0
83
777
1.10
0.27
5.7
5.8
3.69
2.61
ug/l
0.51
72
696
9
75
1.21
0.25
1.2
1.2
—
3.54
—
0
5
21
180
1.18
0.24
5.9
4.3
—
—
—
0
0
5
39
1.29
0.23
5.4
2.6
1.15
1.20
mmol/l
—
5
39
5
40
1.26
0.22
5.4
2.5
4.30
4.08
mmol/l
—
5
40
5
40
1.26
0.22
5.4
2.5
106.00
105.75
mmol/l
—
5
40
27
239
1.15
0.22
1.7
1.3
—
—
—
0
0
38
345
1.12
0.22
1.3
1.3
59.99
36.78
iu/ml
0.41
14
125
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
76.10
—
0
10
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
6
50
1.20
0.20
1.3
1.3
—
—
—
0
0
32
291
1.11
0.18
1.3
1.3
—
—
—
0
0
28
306
0.90
0.15
1.6
1.3
1.41
11.61
u/ml
—
8
111
10
117
0.85
0.13
1.2
1.2
101.45
276.18
u/ml
—
10
106
12
104
1.16
0.12
1.4
1.4
—
—
—
0
0
10
115
0.86
0.11
1.2
1.3
—
—
—
0
0
18
165
1.10
0.09
1.8
1.6
—
—
—
0
0
43
449
0.95
0.08
1.3
1.3
0.86
1.78
u/ml
—
10
117
8
78
1.03
0.07
4.6
5.4
—
—
—
0
0
46
469
0.98
0.02
2.0
1.8
1397.00
1206.43
nmol/l
0.43
35
347
52
529
0.98
0.02
2.0
1.9
420.18
442.48
pmol/l
0.29
40
432
46
467
0.98
0.01
3.4
3.3
0.99
0.78
ug/l
0.50
33
307
63
636
0.99
0.00
4.1
3.7
—
—
—
0
0
20
196
1.02
0.00
1.4
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
15.76
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
8.36
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
0.00
—
0
7
0
6
0.00
-0.00
0.0
4.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
47.20
—
0
5

Mortality – FinRegistry

Association

Association between endpoint H7_PURENDOPHTHALMITIS and mortality.

Females

Parameter HR [95% CI] p-value
H7_PURENDOPHTHALMITIS 1.168 [0.94, 1.45] 0.163
Birth year 0.996 [0.99, 1.0] 0.398

During the follow-up period (1.1.1998 — 31.12.2019), 234 out of 595 females with H7_PURENDOPHTHALMITIS died.

Males

Parameter HR [95% CI] p-value
H7_PURENDOPHTHALMITIS 1.545 [1.18, 2.02] 0.001
Birth year 0.984 [0.97, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 168 out of 486 males with H7_PURENDOPHTHALMITIS died.

Mortality risk

Mortality risk for people of age

years, who have H7_PURENDOPHTHALMITIS.

N-year risk Females Males
1 0.127% 0.329%
5 0.731% 1.799%
10 1.797% 4.371%
15 3.428% 8.472%
20 5.99% 13.724%

Relationships between endpoints

Index endpoint: H7_PURENDOPHTHALMITIS – Purulent endophthalmitis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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