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This is a non-core endpoint: only basic statistics are computed.

General- and plastic-surgery devices associated with adverse incidents

Endpoint Browser

VWXY20_GENERAL_PLASTIC__DEVICES_ASSOCIATED_W_ADVER_INCIDENTS

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — Y81
  • Cause of death: ICD-10 — Y81

2 out of 7 registries used, show all original rules.

97

4. Check minimum number of events

None

97

5. Include endpoints

None

97

6. Filter based on genotype QC (FinnGen only)

93

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Y7|Y8[0-2]

Case counts by codes

↥

FinnGen case counts by registry codes:

No upset plot: unknown.

No upset table: unknown.

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 93 68 25
Unadjusted period prevalence (%) 0.02 0.02 0.01
Median age at first event (years) 58.79 56.21 65.82

-FinnGen-

Age distribution of first events

0104050607080900246810121416182022AgeIndividuals

-FinnGen-

Year distribution of first events

19701975198019851990199520052010201520202025051015202530YearIndividuals

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
97
Matched controls
970
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Y81
ICD-10 Finland
General- and plastic-surgery devices associated with adverse incidents
+∞
42.9
38
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
15.9
39.8
44
48
Y81.3
ICD-10 Finland
General- and plastic-surgery devices associated with adverse incidents, surgical instruments, materials and devices (including sutures)
+∞
29.7
27
*
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
13.3
27.8
31
33
Y81.2
ICD-10 Finland
General- and plastic-surgery devices associated with adverse incidents, prosthetic and other implants, materials and accessory devices
+∞
18.3
17
*
T85.4
ICD-10 Finland
Mechanical complication of breast prosthesis and implant
189.3
16.0
16
*
HAD60
NOMESCO Finland
Replacement of prosthetic implant in breast
+∞
11.7
11
*
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
25.0
11.1
15
7
HAD50
NOMESCO Finland
Removal of prosthetic implant from breast
122.7
10.6
11
*
Y81.8
ICD-10 Finland
General- and plastic-surgery devices associated with adverse incidents, miscellaneous devices, not elsewhere classified
+∞
10.6
10
*
HAE00
NOMESCO Finland
Reconstruction of breast using prosthesis
+∞
10.6
10
*
ZXD05
NOMESCO Finland
Urgent procedure
3.4
8.1
46
203
ZXE20
NOMESCO Finland
More than three and less than five hours
4.1
7.8
26
80
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
22.0
7.3
10
5
HAE99
NOMESCO Finland
Other reconstruction of breast
22.0
7.3
10
5
HAC15
NOMESCO Finland
Subcutaneous mastectomy with excision of mamilla
32.7
7.3
9
*
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
11.2
6.7
12
12
N02AX02
ATC
tramadol; systemic, rectal
3.0
6.6
56
302
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
5.9
6.6
18
36
N03AX12
ATC
[U] gabapentin; oral
3.4
6.6
29
107
HWA00
NOMESCO Finland
Repair of wound dehiscence in surgery of mammary gland
74.5
6.5
7
*
Z42.1
ICD-10 Finland
Follow-up care involving plastic surgery of breast
+∞
6.3
6
*
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
11.1
6.2
11
11
TQW11
NOMESCO Finland
Vacuum treatment of wound
16.3
6.0
9
6
ZXA05
NOMESCO Finland
Left side
3.0
6.0
36
159

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
40
124
4.79
12.41
2.2
1.6
—
—
—
0
0
25
85
3.62
6.42
2.0
1.6
—
—
—
0
0
36
202
2.24
3.41
5.1
4.1
—
—
—
0
0
23
116
2.29
2.74
2.2
2.4
6.11
3.25
e6/l
0.22
13
61
26
142
2.14
2.55
4.1
3.2
379.47
75.61
ng/l
0.46
19
106
39
253
1.91
2.37
3.3
2.2
—
—
—
0
0
69
557
1.83
1.91
4.4
4.3
—
427.33
—
0
12
47
346
1.70
1.76
3.1
2.0
—
—
—
0
0
27
170
1.82
1.74
1.3
1.3
9.31
33.28
iu/ml
—
8
60
34
231
1.73
1.69
2.8
2.5
—
—
—
0
0
15
78
2.09
1.65
1.7
1.4
—
—
—
0
0
44
324
1.66
1.61
2.0
2.0
99.62
98.52
pmol/l
0.04
24
158
17
94
1.98
1.60
12.8
7.6
105.06
103.21
mmol/l
1.37
17
94
18
102
1.94
1.58
1.9
1.2
—
—
—
0
0
5
15
3.45
1.54
1.0
1.0
—
—
—
0
0
26
175
1.66
1.31
3.7
3.8
—
—
—
0
0
21
309
0.59
1.30
2.6
3.0
—
—
—
0
0
5
18
2.87
1.30
1.2
1.2
—
—
—
0
0
11
56
2.09
1.28
17.5
9.5
—
—
—
0
0
32
230
1.58
1.24
3.1
2.5
0.28
0.45
e6/l
0.49
25
177
34
249
1.56
1.22
3.0
2.9
10.73
284.78
e6/l
0.55
27
194
24
165
1.60
1.11
1.3
1.3
1.09
10.86
u/ml
—
8
56
39
302
1.49
1.06
3.4
3.3
68.51
47.27
e6/l
0.20
29
211
30
221
1.52
1.03
6.4
8.6
—
—
—
0
0
0
28
0.00
0.99
0.0
1.3
—
—
—
0
0
67
583
1.48
0.98
4.4
4.1
—
—
—
0
0
51
427
1.41
0.88
5.4
5.9
1.86
2.06
e9/l
0.33
46
377
50
418
1.40
0.87
5.2
5.8
0.05
0.04
e9/l
0.86
43
358
50
418
1.40
0.87
5.2
5.8
0.62
0.58
e9/l
0.35
43
359
6
31
2.00
0.86
2.0
4.8
—
—
—
0
0
11
172
0.59
0.83
3.3
5.0
1.36
2.14
ug/l
0.67
11
154
6
33
1.87
0.80
1.2
1.2
—
—
—
0
0
0
24
0.00
0.80
0.0
1.3
—
—
—
0
0
0
24
0.00
0.80
0.0
1.3
—
—
—
0
0
0
24
0.00
0.80
0.0
1.4
—
—
—
0
0
0
26
0.00
0.79
0.0
1.4
—
—
—
0
0
0
27
0.00
0.78
0.0
1.4
—
—
—
0
0
0
27
0.00
0.78
0.0
1.7
—
—
—
0
0
0
27
0.00
0.78
0.0
1.4
—
—
—
0
0
0
27
0.00
0.78
0.0
1.4
—
—
—
0
0
9
53
1.77
0.78
2.6
4.8
—
—
—
0
0
7
38
1.91
0.75
1.4
1.1
—
—
—
0
0
5
25
2.05
0.74
2.0
4.0
12.00
47.12
u/ml
—
5
25
7
42
1.72
0.70
2.7
2.2
—
—
—
0
0
50
429
1.34
0.69
5.2
6.2
0.21
0.19
e9/l
0.43
43
374
7
43
1.68
0.68
5.4
8.4
25.26
25.44
mmol/l
—
7
43
46
393
1.32
0.65
5.7
6.1
—
—
—
0
0
5
29
1.76
0.64
2.2
4.2
—
—
—
0
0
77
819
0.71
0.60
4.7
4.5
1.45
1.54
mmol/l
1.13
71
755
0
22
0.00
0.60
0.0
1.2
—
—
—
0
0
0
23
0.00
0.59
0.0
1.4
—
—
—
0
0
47
409
1.29
0.56
6.4
6.2
1.21
1.22
mmol/l
0.06
40
338
9
62
1.50
0.55
1.4
1.4
—
—
—
0
0
6
40
1.53
0.52
26.8
7.5
—
—
—
0
0
46
403
1.27
0.51
4.9
5.1
0.00
0.00
estimate
—
7
79
11
76
1.50
0.50
1.0
1.1
—
—
—
0
0
15
111
1.42
0.50
1.3
1.4
—
—
—
0
0
68
625
1.29
0.50
4.4
4.5
14.16
11.73
mm/h
0.53
63
566
78
823
0.73
0.50
4.6
4.5
4.69
4.74
mmol/l
0.18
72
764
42
365
1.27
0.49
7.8
9.8
0.00
0.00
e9/l
0.71
30
293
25
203
1.31
0.49
1.1
1.3
0.51
1.28
u/ml
—
7
59
46
406
1.25
0.47
3.2
3.8
0.00
0.00
estimate
—
7
74
31
262
1.27
0.45
1.9
4.2
7.39
7.40
ph
—
6
51
63
578
1.26
0.45
3.7
3.8
—
—
—
0
0
84
874
0.71
0.44
23.0
16.1
71.15
74.90
umol/l
1.11
84
874
45
399
1.24
0.43
3.2
3.8
0.00
0.00
estimate
—
7
86
0
15
0.00
0.41
0.0
3.1
—
—
—
0
0
8
60
1.36
0.41
2.3
3.8
—
—
—
0
0
0
16
0.00
0.41
0.0
2.2
—
—
—
0
0
12
158
0.73
0.41
1.7
1.9
—
—
—
0
0
19
152
1.31
0.41
1.2
1.8
857.43
1143.85
nmol/l
0.99
14
117
5
34
1.50
0.41
1.2
1.2
—
—
—
0
0
70
654
1.25
0.40
8.5
7.8
88.12
79.54
u/l
0.43
65
607
19
231
0.78
0.38
1.3
1.5
—
—
—
0
0
6
44
1.39
0.35
3.2
3.5
3907.67
42.85
u/ml
—
6
39
10
132
0.73
0.35
1.5
1.6
—
—
—
0
0
41
367
1.20
0.34
22.8
14.4
1.27
1.28
inr
—
10
111
76
795
0.80
0.34
4.1
4.0
1.34
1.25
mmol/l
0.57
71
723
29
252
1.22
0.32
2.0
2.8
—
—
—
0
0
69
651
1.21
0.31
3.3
4.2
14.99
14.69
pmol/l
0.54
60
601
21
245
0.82
0.29
3.8
4.0
—
—
—
0
0
21
178
1.23
0.29
3.0
1.8
1.73
1.10
mg/l
0.32
16
142
10
76
1.35
0.29
2.5
3.7
—
—
—
0
0
8
66
1.23
0.27
1.4
1.4
—
—
—
0
0
5
74
0.66
0.27
3.6
3.4
—
—
—
0
0
20
231
0.83
0.25
2.8
2.8
6.15
7.47
mmol/l
0.97
14
196
6
83
0.70
0.25
1.3
1.4
—
—
—
0
0
81
836
0.81
0.25
4.9
5.0
2.71
2.79
mmol/l
0.27
75
771
12
97
1.27
0.24
2.0
1.3
—
—
—
0
0
15
125
1.24
0.24
1.7
1.4
1416.00
455.48
titre
—
5
31
0
11
0.00
0.21
0.0
3.3
—
3.95
—
0
11
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
3.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
3.3
—
105.18
—
0
11
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
4.5
—
—
—
0
0
0
10
0.00
0.21
0.0
5.5
—
390.40
—
0
10
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
1.9
—
5.06
—
0
7
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
25
224
1.16
0.19
2.1
2.7
337.80
4018.95
umol/l
0.79
20
191
12
140
0.84
0.16
2.6
3.0
0.85
0.82
mmol/l
0.70
12
132
84
820
1.18
0.16
21.7
14.1
31.57
20.28
mg/l
1.91
68
637
8
98
0.80
0.14
1.6
1.5
—
—
—
0
0
17
190
0.87
0.14
1.5
1.5
1.75
2.77
g/l
—
9
112
21
229
0.89
0.12
3.1
3.5
4.60
9.06
mg/mmol
0.82
13
132
11
96
1.16
0.11
3.2
4.6
1.02
1.03
mmol/l
0.05
11
87
5
45
1.12
0.10
1.0
3.8
3.92
4.81
pmol/l
—
5
38
5
63
0.78
0.08
1.8
1.7
1.68
1.30
g/l
—
5
53
76
774
0.92
0.08
5.6
5.7
38.73
40.11
mmol/mol
0.89
69
726
8
93
0.85
0.07
1.5
1.7
—
—
—
0
0
11
121
0.90
0.06
1.4
1.2
—
—
—
0
0
20
210
0.94
0.04
2.4
4.4
0.00
0.00
estimate
—
7
78
81
803
1.05
0.01
4.6
4.6
5.91
5.89
mmol/l
0.04
72
741
86
857
1.03
0.00
18.4
12.9
—
—
—
0
0
31
311
1.00
0.00
3.5
4.1
13.94
30.02
ng/l
1.59
20
216
24
237
1.02
0.00
2.0
3.3
—
—
—
0
0
21
214
0.98
0.00
2.8
3.1
28.82
642.68
mg/l
0.85
13
138
77
771
0.99
0.00
4.5
5.0
1.75
1.88
mu/l
0.58
69
708
0
9
0.00
0.00
0.0
2.0
—
0.86
—
0
9
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
12.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.0
—
1856.67
—
0
6
7
75
0.93
-0.00
2.4
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
1.61
—
0
6
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
30.08
—
0
5
0
5
0.00
-0.00
0.0
16.0
—
941.00
—
0
5
0
6
0.00
-0.00
0.0
1.3
—
6.97
—
0
6
7
72
0.97
-0.00
3.3
2.5
10.77
10.13
g/l
—
7
63
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.3
—
61.86
—
0
8
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
21.0
—
1789.80
—
0
5
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
2.18
—
0
5
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
7
72
0.97
-0.00
5.4
5.4
6.97
9.74
mmol/l
—
7
67
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
77
0.90
-0.00
1.1
1.3
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: VWXY20_GENERAL_PLASTIC__DEVICES_ASSOCIATED_W_ADVER_INCIDENTS – General- and plastic-surgery devices associated with adverse incidents

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).