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Disorders of magnesium metabolism

DOID Endpoint Browser PheWeb

E4_MG_MET

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — E83.4
  • Hospital discharge: ICD-9 — 2752
  • Cause of death: ICD-10 — E83.4
  • Cause of death: ICD-9 — 2752

2 out of 7 registries used, show all original rules.

329

4. Check minimum number of events

None

329

5. Include endpoints

None

329

6. Filter based on genotype QC (FinnGen only)

293

Control definitions (FinnGen only)

Control exclude
E4_METABOLIA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
E83
Name in latin
Perturbationes metabolismi magnesii

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1471 688 778
Only index persons 1406 660 746
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.02
Only index persons 0.03 0.02 0.03
Median age at first event (years)
Whole population 64.94 65.77 64.25
Only index persons 65.12 66.02 64.32

-FinnGen-

Key figures

All Female Male
Number of individuals 293 134 159
Unadjusted period prevalence (%) 0.06 0.05 0.07
Median age at first event (years) 67.24 64.16 69.83

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
298
Matched controls
2980
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E83.4
ICD-10 Finland
Disorders of magnesium metabolism
+∞
307.7
298
*
E87.6
ICD-10 Finland
Hypokalaemia
148.9
222.8
112
12
E83.51
ICD-10 Finland
Hypocalcemia
509.3
107.7
101
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
7.5
64.4
133
290
TPX10
NOMESCO Finland
Implantation of vascular injection port
15.8
60.5
56
43
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
76.1
50.3
56
9
C03CA01
ATC
furosemide; systemic
5.6
48.6
160
514
N17.9
ICD-10 Finland
Acute renal failure, unspecified
14.1
47.3
46
38
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
8.2
46.5
71
109
A49.9
ICD-10 Finland
Bacterial infection, unspecified
6.7
46.3
91
183
WW500
NOMESCO Finland
Blood transfusion
11.2
45.5
52
55
N02AA05
ATC
oxycodone; systemic
5.4
44.3
127
359
130
Kela drug reimbursment
Malignant tumour
6.4
44.1
91
191
D64.9
ICD-10 Finland
Anaemia, unspecified
6.7
44.1
86
171
JN3AD
NOMESCO Finland
Abdominal CT examination
6.1
43.5
97
219
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
5.5
43.0
115
305
R56.8
ICD-10 Finland
Other and unspecified convulsions
10.1
42.2
52
61
WX302
NOMESCO Finland
Thoracal epidural anesthesy
9.9
42.1
53
64
TPH07
NOMESCO Finland
Cathetrisation of artery
6.2
40.3
84
177
AA1AD
NOMESCO Finland
CT of head and brain
4.7
39.2
152
538
R11
ICD-10 Finland
Nausea and vomiting
6.9
37.9
68
123
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
7.3
36.4
60
99
A03FA01
ATC
metoclopramide; systemic, rectal
4.5
36.0
133
449
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
4.4
35.8
170
689
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
7.3
35.1
58
96
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
4.3
34.9
154
590
E86
ICD-10 Finland
Volume depletion
102.0
33.5
36
*
JN4AD
NOMESCO Finland
Body CT examination
5.0
33.4
91
240
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.7
33.1
221
1125
TPH04
NOMESCO Finland
Cathetrisation of vein
4.3
32.4
121
407
Z51.5
ICD-10 Finland
Palliative care
5.5
32.0
74
169
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
10.4
31.6
37
40
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
8.4
31.4
44
60
H02AB02
ATC
dexamethasone; systemic
4.8
31.0
88
239
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
7.7
30.7
47
71
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
11.2
30.6
34
34
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
6.9
29.3
50
85
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.9
29.3
131
495
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
8.4
28.7
40
54
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
5.3
28.7
68
158
E83.39
ICD-10 Finland
Other disorder of phosphorus metabolism
+∞
27.5
26
*
SPAT1262
SPAT
Handing over of treatment supplies
4.2
27.0
96
306
ZXD05
NOMESCO Finland
Urgent procedure
3.7
26.3
131
525
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
5.4
25.5
57
125
A04AA02
ATC
granisetron; systemic, transdermal
5.3
24.3
55
122
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
6.5
23.9
42
73
WZC00
NOMESCO Finland
Treatment plan or consultation
3.3
23.4
159
761
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.1
22.8
77
234
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
5.2
22.2
51
114
B01AB10
ATC
tinzaparin; parenteral
4.0
21.4
73
223
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
8.3
21.2
29
38
A11CC03
ATC
alfacalcidol; systemic
20.2
20.9
31
17
E61.2
ICD-10 Finland
Magnesium deficiency
225.1
20.8
21
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
8.5
20.8
28
36
EBA15
NOMESCO Finland
Extraction of multiple teeth
7.4
20.4
31
46
SPAT1255
SPAT
Intravenous administration of medicine
5.4
20.4
44
93
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
3.2
19.5
105
429
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
7.8
19.4
28
39
N19
ICD-10 Finland
Unspecified kidney failure
8.1
19.4
27
36
J01MA12
ATC
levofloxacin; systemic
3.4
19.4
94
360
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
4.7
19.3
49
119
JN4BD
NOMESCO Finland
Extensive body CT
3.8
18.9
67
209
B03BA03
ATC
hydroxocobalamin; parenteral
5.7
18.7
37
72
A41.9
ICD-10 Finland
Sepsis, unspecified
6.7
18.5
31
51
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
4.7
18.5
47
114
UJF32
NOMESCO Finland
Coloscopy
3.0
18.5
119
536
WZC30
NOMESCO Finland
Teaching
3.3
18.1
90
348
GD1AD
NOMESCO Finland
Thorax CT examination
4.7
18.0
46
112
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.5
17.9
76
267
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
3.0
17.8
109
476
XX3DW
NOMESCO Finland
Time consuming IT work
3.6
17.7
70
234
JAH00
NOMESCO Finland
Laparotomy
7.9
17.7
25
34
E87.5
ICD-10 Finland
Hyperkalaemia
45.0
17.5
21
5
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
33.8
17.3
22
7
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.2
17.2
52
144
215
Kela drug reimbursment
Diabetes, non-insulin-treated
3.0
17.0
107
473
R79.0
ICD-10 Finland
Abnormal level of blood mineral
+∞
16.8
16
*
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
3.9
16.6
56
168
103
Kela drug reimbursment
Diabetes, insulin-treated
2.9
16.4
111
508
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
6.1
16.4
30
54
C03DA01
ATC
spironolactone; oral
3.8
16.3
58
180
M04AA01
ATC
allopurinol; systemic
3.4
16.2
68
236
205
Kela drug reimbursment
Chronic hypertension
2.9
15.8
102
454
A28
ICPC
Limited function/disability NOS
3.2
15.7
77
293
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.6
15.7
61
201
F10.25
ICD-10 Finland
Alcohol dependence continuous use
14.1
15.5
26
20
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
7.5
15.5
23
33
N07BB01
ATC
disulfiram; oral
5.4
15.4
32
65
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
5.8
15.3
29
54
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.6
15.1
58
189
N02AX02
ATC
tramadol; systemic, rectal
2.6
15.1
165
954
T36
ICD-10 Finland
Poisoning by systemic antibiotics
6.4
15.1
26
44
SPAT1254
SPAT
Administration of medicine
3.4
15.0
65
229
WX892
NOMESCO Finland
Monitored bed care
4.4
15.0
41
105
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
19.7
14.9
22
12
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
3.7
14.8
52
160
JFB00
NOMESCO Finland
Partial resection of small intestine
13.5
14.7
25
20
D07AA02
ATC
hydrocortisone; topical
3.3
14.6
64
227
I50.9
ICD-10 Finland
Heart failure, unspecified
3.5
14.6
57
188
C08CA01
ATC
amlodipine; oral
2.6
14.5
147
814
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
25.2
14.0
19
8
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.6
13.9
51
161
A02BC02
ATC
pantoprazole; systemic
3.0
13.8
238
1691
WX408
NOMESCO Finland
General anesthesy, balanced
2.6
13.4
104
502
H02AB06
ATC
prednisolone; systemic
2.5
13.4
174
1071
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
5.4
13.2
27
54
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.5
13.1
125
666
B81
ICPC
Anaemia vit B12/folate deficiency
6.1
12.9
23
40
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
6.3
12.8
22
37
M10.9
ICD-10 Finland
Gout, unspecified
3.9
12.8
40
113
E83.50
ICD-10 Finland
Hypercalcemia
73.1
12.7
14
*
I10
ICD-10 Finland
Essential (primary) hypertension
2.6
12.7
215
1480
WX402
NOMESCO Finland
General anaesthesia
2.6
12.7
93
436
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
6.0
12.6
23
41
N06AX11
ATC
mirtazapine; oral
2.5
12.6
121
644
D70.82
ICD-10 Finland
Drug-induced neutropenia
12.4
12.5
22
19
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
15.2
12.5
20
14
R50.9
ICD-10 Finland
Fever, unspecified
3.0
12.4
64
249
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
10.7
12.2
23
23
A04AA01
ATC
ondansetron; systemic, rectal
3.4
12.1
48
159
B01AB05
ATC
enoxaparin; parenteral
2.4
11.9
122
666
C07AB07
ATC
bisoprolol; oral
2.4
11.9
171
1081
ZX095
NOMESCO Finland
Combined chemoradiotherapy
17.3
11.8
18
11
F10.20
ICD-10 Finland
Alcohol dependence currently independent
9.2
11.8
24
28
V03AE01
ATC
polystyrene sulfonate; oral
19.9
11.7
17
9
WVC10
NOMESCO Finland
Subcutaneous infusion of drugs
24.0
11.7
16
7
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
6.0
11.6
21
37
OAB73
NOMESCO Finland
Prevention and treatment of malnutrition
15.9
11.5
18
12
L01BC06
ATC
capecitabine; oral
4.4
11.4
30
74
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
3.7
11.4
39
117
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
2.8
11.2
67
281
T90
ICPC
Diabetes non-insulin dependent
2.5
11.1
97
489
K08.3
ICD-10 Finland
Retained dental root
3.7
11.1
37
109
E0000UV, ,
ATC
2.3
11.0
144
866
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
4.9
10.9
25
55
A10AE04
ATC
insulin glargine; parenteral
3.5
10.9
41
131
WF049
NOMESCO Finland
Radiotherapy of metastasis
4.5
10.8
27
64
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
3.5
10.7
40
127
P15
ICPC
Chronic alcohol abuse
5.1
10.7
23
48
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.7
10.7
36
107
A06AD11
ATC
lactulose; oral
2.9
10.6
55
213
N03AX14
ATC
levetiracetam; systemic
8.2
10.6
23
30
WX872
NOMESCO Finland
Intensive care
4.2
10.6
29
74
ZXE00
NOMESCO Finland
One hour or less
2.3
10.6
132
775
R53
ICD-10 Finland
Malaise and fatigue
2.5
10.5
88
434
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.1
10.5
49
179
E78.00
ICD-10 Finland
Familial hypercholesterolaemia
19.7
10.4
15
8
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
9.7
10.2
20
22
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.2
10.2
144
886
K70.1
ICD-10 Finland
Alcoholic hepatitis
41.6
10.0
12
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.8
10.0
57
232
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
12.8
10.0
17
14
C02AC05
ATC
moxonidine; oral
4.8
10.0
23
51
A10BA02
ATC
metformin; oral
2.3
9.9
103
558
A04AA55
ATC
palonosetron, combinations; systemic
4.6
9.8
24
56
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
8.8
9.7
20
24
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
4.0
9.7
29
79
R60.9
ICD-10 Finland
Oedema, unspecified
4.1
9.6
27
70
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
8.0
9.6
21
28
N30.0
ICD-10 Finland
Acute cystitis
2.7
9.6
59
250
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
4.6
9.5
23
53
A04
ICPC
Weakness/tiredness general
2.8
9.5
54
220
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
9.1
9.4
19
22
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.8
9.3
52
209
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.1
9.3
43
156
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.2
9.3
109
618
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
3.3
9.2
37
123
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.6
9.1
61
269
A02BC05
ATC
esomeprazole; systemic
2.1
9.1
137
853
A46
ICD-10 Finland
Erysipelas
2.7
9.1
57
244
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
19.3
9.0
13
7
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
8.4
9.0
19
24
SPAT1301
SPAT
No procedures
2.2
8.9
109
626
A10BB12
ATC
glimepiride; oral
3.6
8.9
30
89
B03XA02
ATC
darbepoetin alfa; parenteral
8.0
8.8
19
25
K92.1
ICD-10 Finland
Melaena
3.7
8.7
29
85
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.0
8.7
25
66
A09AA02
ATC
multienzymes (lipase, protease etc.); oral
6.8
8.7
21
33
JDB10
NOMESCO Finland
Percutaneous gastrostomy
9.4
8.7
17
19
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.8
8.6
49
199
R03BB04
ATC
tiotropium bromide; inhalant
2.9
8.6
43
163
E55.9
ICD-10 Finland
Vitamin D deficiency, unspecified
20.8
8.5
12
6
NF1AA
NOMESCO Finland
Hip X-ray examination
3.0
8.5
40
146
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
8.3
8.5
18
23
L28
ICPC
Limited function/disability (L)
2.4
8.5
67
319
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.4
8.4
71
348
F10.30
ICD-10 Finland
Withdrawal symptoms caused by alcohol uncomplicated
11.2
8.4
15
14
H02AB09
ATC
hydrocortisone; systemic
9.9
8.4
16
17
F10.24
ICD-10 Finland
Alcohol depence active use
9.9
8.4
16
17
J01MA02
ATC
ciprofloxacin; systemic
2.1
8.4
133
839
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
3.3
8.3
33
109
8140/3-C20.9
ICD-O-3
Adenocarcinoma, NOS, of rectum, NOS
7.9
8.3
18
24
F10.40
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without seizures
15.0
8.3
13
9
SPAT1229
SPAT
Assessment of need for aid
3.4
8.2
31
99
N05CF01
ATC
zopiclone; oral
2.1
8.2
105
610
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
12.2
8.2
14
12
SPAT1263
SPAT
Sampling
2.0
8.1
135
864
X59
ICD-10 Finland
Exposure to unspecified factor
2.3
8.1
70
347
WX110
NOMESCO Finland
Infiltration anesthesia
2.2
8.1
223
1712
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
4.7
8.0
19
43
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
3.2
8.0
34
117
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
6.4
8.0
20
33
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
8.1
8.0
17
22
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.0
8.0
37
134
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.5
8.0
57
259
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
3.9
7.9
24
66
C20.90
ICD-10 Finland
Malignant tumor of the rectum without histology
11.2
7.9
14
13
F05.9
ICD-10 Finland
Delirium, unspecified
9.8
7.9
15
16
XCK10
NOMESCO Finland
Photography of fundus of eye
3.0
7.8
36
130
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
3.1
7.8
34
119
J01MA14
ATC
moxifloxacin; systemic
2.9
7.8
38
142
ZXE20
NOMESCO Finland
More than three and less than five hours
2.5
7.8
54
242
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.7
7.8
18
40
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
3.2
7.7
32
109
XGX32
NOMESCO Finland
Bronchoscopic ultrasonography
12.3
7.6
13
11
J01DB01
ATC
cefalexin; oral
2.5
7.6
255
2088
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
7.4
7.6
17
24
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
3.8
7.6
24
68
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.0
7.5
35
127
N02BE01
ATC
paracetamol; systemic, rectal
3.6
7.5
279
2396
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.8
7.5
23
64
SPAT1247
SPAT
Outpatient detoxication and monitoring
82.1
7.5
8
*
WX725
NOMESCO Finland
Noninvasive ventilation
3.4
7.4
27
84
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
8.7
7.4
15
18
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
8.7
7.4
15
18
TK800
NOMESCO Finland
Hemodialysis
7.1
7.4
17
25
ZX120
NOMESCO Finland
Intravenous
2.8
7.4
40
158
N03AX12
ATC
[U] gabapentin; oral
2.3
7.3
62
303
E46
ICD-10 Finland
Unspecified protein-energy malnutrition
+∞
7.3
7
*
E87.8
ICD-10 Finland
Other disorders of electrolyte and fluid balance, not elsewhere classified
+∞
7.3
7
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.4
7.3
57
269
F10.09
ICD-10 Finland
Alcohol intoxication UNS
7.6
7.3
16
22
E11
ICD-10 Finland
Type 2 diabetes mellitus
2.3
7.3
61
297
S97
ICPC
Chronic ulcer skin
3.1
7.3
31
107
TKC20
NOMESCO Finland
Catheterisation of bladder
3.3
7.2
28
91
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
3.3
7.2
28
91
A10BH01
ATC
sitagliptin; oral
2.7
7.2
41
166
C10AA01
ATC
simvastatin; oral
2.0
7.2
125
804
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
3.8
7.2
22
61
S01.0
ICD-10 Finland
Open wound of scalp
2.9
7.1
34
125
N18.8
ICD-10 Finland
Other chronic renal failure
10.4
7.1
13
13
A10AB05
ATC
insulin aspart; parenteral
3.1
7.1
30
103
N05AH04
ATC
quetiapine; oral
2.3
7.1
58
280
K92.0
ICD-10 Finland
Haematemesis
6.6
7.0
17
27
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
5.7
7.0
19
35
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.1
7.0
31
109
A01
ICPC
Pain general/multiple sites
2.7
7.0
39
156
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.1
7.0
75
404
K70.0
ICD-10 Finland
Alcoholic fatty liver
14.2
6.9
11
8
R06AE07
ATC
cetirizine; oral
1.9
6.9
130
855
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
4.3
6.9
18
44
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
7.0
6.9
16
24
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.0
6.9
91
530
J01FF01
ATC
clindamycin; systemic
2.0
6.9
92
538
NA1AD
NOMESCO Finland
Cervical spine CT examination
3.8
6.9
21
58
ZX070
NOMESCO Finland
Intensity modified radiotherapy
5.9
6.9
18
32
K59.1
ICD-10 Finland
Functional diarrhoea
3.4
6.9
25
78
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.7
6.9
40
164
N05CD07
ATC
temazepam; oral
2.7
6.9
39
158
WVA20
NOMESCO Finland
Medicine administration
4.4
6.8
17
40
G72.8
ICD-10 Finland
Other specified myopathies
7.5
6.8
15
21
P16
ICPC
Acute alcohol abuse
7.5
6.8
15
21
JWA00
NOMESCO Finland
Repair of wound dehiscence in gastroenterological surgery
41.0
6.8
8
*
YHMAS, ,
NOMESCO Finland
41.0
6.8
8
*
JFF13
NOMESCO Finland
Terminal enterostomy
41.0
6.8
8
*
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
6.1
6.7
17
29
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
6.1
6.7
17
29
WX882
NOMESCO Finland
High dependency care
6.1
6.7
17
29
F10.49
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without information about seizures
23.1
6.7
9
*
UJF92
NOMESCO Finland
Capsular endoscopy
8.1
6.7
14
18
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
8.1
6.7
14
18
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.7
6.7
37
148
C07AB02
ATC
metoprolol; systemic
2.2
6.6
61
309
C09AA02
ATC
enalapril; systemic
2.2
6.5
67
354
EBA10
NOMESCO Finland
Operative extraction of tooth
2.6
6.5
38
156
C03AA03
ATC
hydrochlorothiazide; oral
2.9
6.5
32
120
JFF10
NOMESCO Finland
Loop enterostomy
71.3
6.4
7
*
F10.22
ICD-10 Finland
Alcohol dependence is currently on clinically controlled discontinuation medication
71.3
6.4
7
*
JJA20
NOMESCO Finland
Open biopsy of liver
71.3
6.4
7
*
N03AX16
ATC
[U] pregabalin
2.1
6.4
72
393
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
4.2
6.4
17
42
XF400
NOMESCO Finland
ECG with 12 standard connections
2.3
6.4
53
256
D10
ICPC
Vomiting
3.6
6.4
21
61
S18
ICPC
Laceration/cut
1.9
6.4
162
1164
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
8.4
6.4
13
16
WPA10
NOMESCO Finland
Proactive palliative care treatment plan
11.4
6.3
11
10
I50.0
ICD-10 Finland
Congestive heart failure
3.1
6.3
27
93
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
7.3
6.3
14
20
K91.2
ICD-10 Finland
Postsurgical malabsorption, not elsewhere classified
+∞
6.3
6
*
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
4.1
6.3
17
43
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
4.1
6.3
17
43
L89
ICD-10 Finland
Decubitus ulcer and pressure area
6.5
6.2
15
24
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
6.5
6.2
15
24
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.8
6.2
33
129
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
7.9
6.2
13
17
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
3.9
6.2
18
48
R55
ICD-10 Finland
Syncope and collapse
2.6
6.2
38
160
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
4.3
6.2
16
39
N17.8
ICD-10 Finland
Other acute renal failure
12.9
6.1
10
8
R13
ICD-10 Finland
Dysphagia
2.8
6.1
31
118
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
3.2
6.1
25
84
D64.8
ICD-10 Finland
Other specified anaemias
8.9
6.1
12
14
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
6.9
6.1
14
21
R06.0
ICD-10 Finland
Dyspnoea
1.9
6.1
90
542
ED1AA
NOMESCO Finland
Mandibular X-ray examination
10.3
6.1
11
11
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
10.3
6.1
11
11
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
3.3
6.0
23
74
M05BX04
ATC
denosumab; parenteral
3.1
6.0
25
85

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
207
318
19.04
151.74
11.7
5.5
1.00
1.02
mmol/l
0.33
202
292
108
168
9.51
71.95
5.1
3.6
105.26
91.03
ng/l
0.49
96
143
166
416
7.75
70.94
4.0
2.4
2.16
2.31
g/l
1.91
161
386
221
747
8.58
68.97
8.4
4.3
—
—
—
0
0
159
394
7.51
68.29
3.8
2.4
21.16
23.38
%
0.99
154
371
169
452
7.33
66.87
4.1
2.4
10.70
13.47
umol/l
4.47
163
425
129
297
6.90
58.44
2.9
2.6
0.19
0.21
g/l
2.31
119
280
276
1306
16.08
56.97
27.2
7.0
1.16
1.21
mmol/l
12.92
220
1125
195
671
6.51
56.57
3.7
2.1
2.99
3.03
mg/l
0.07
182
595
211
780
6.84
56.40
12.6
4.2
7.40
7.40
ph
0.32
180
565
262
1184
11.04
56.29
20.7
6.2
1.16
1.21
mmol/l
13.74
256
1085
115
245
7.02
56.13
3.1
2.1
389.27
366.43
nmol/l
0.46
110
231
260
1186
10.35
54.60
14.5
5.1
32.00
35.54
g/l
18.26
255
1123
52
48
12.91
50.02
3.9
3.6
—
—
—
0
0
258
1255
8.87
47.67
17.3
13.6
1.20
1.24
inr
0.65
235
1049
221
950
6.13
46.66
6.8
3.8
2.25
2.36
mmol/l
9.48
204
860
129
364
5.49
45.18
12.1
6.8
101.95
104.41
mmol/l
3.57
129
364
86
170
6.71
44.36
5.7
3.4
7.42
7.42
ph
0.08
76
145
105
258
5.74
42.85
5.4
3.2
62.86
68.82
e9/l
0.96
76
202
96
220
5.96
42.27
10.0
3.6
1.18
1.23
mmol/l
4.45
91
188
69
115
7.51
41.79
2.5
2.1
1.51
4.21
ug/l
0.55
64
103
99
242
5.63
40.41
10.9
3.2
7.38
7.39
ph
0.33
73
130
44
46
11.05
38.66
5.1
3.7
2.97
2.78
mmol/l
0.10
36
28
231
1142
5.55
37.99
4.4
2.3
69.64
77.80
nmol/l
3.54
216
1012
113
326
4.97
37.63
5.1
3.1
1.96
1.79
%
0.96
101
301
94
237
5.33
36.71
10.8
3.2
2.73
2.01
mmol/l
0.58
86
204
186
796
4.56
36.58
2.6
1.7
18.57
20.47
nmol/l
0.81
163
657
64
118
6.63
34.90
1.5
2.4
1.56
1.54
g/l
0.05
58
104
125
412
4.50
34.71
3.2
2.0
—
—
—
0
0
105
305
4.77
34.30
12.2
8.0
7.42
7.42
ph
0.06
67
171
103
298
4.75
33.75
12.0
8.1
1.56
1.00
mmol/l
0.52
90
256
262
1512
7.07
33.62
22.0
10.3
4.78
3.97
e9/l
4.85
250
1331
194
896
4.34
33.38
8.1
6.4
—
—
—
0
0
170
730
4.09
32.12
4.4
2.9
—
—
—
0
0
136
503
4.13
31.78
4.2
2.7
483.79
545.22
mosm/kgh2o
2.80
123
435
232
1246
4.89
31.72
9.3
6.7
9.38
9.02
%
0.82
226
1172
244
1366
5.34
31.43
9.2
6.5
1.74
1.93
e9/l
0.60
226
1223
241
1341
5.17
31.18
9.0
6.5
0.78
0.58
e9/l
1.91
223
1157
233
1268
4.84
30.96
9.2
6.6
21.72
27.27
%
10.88
227
1206
47
71
7.67
30.73
1.7
1.4
199.01
260.93
ug/g
0.96
30
44
100
302
4.48
30.69
2.4
1.7
—
—
—
0
0
241
1350
5.11
30.66
9.0
6.4
0.05
0.04
e9/l
0.58
222
1163
229
1243
4.64
30.21
9.3
6.6
0.56
0.68
%
2.57
223
1166
244
1394
5.14
29.85
9.2
6.6
0.18
0.19
e9/l
0.35
225
1225
228
1245
4.54
29.53
9.2
6.5
2.28
2.86
%
3.65
222
1169
121
438
3.97
28.67
2.3
1.6
1484.37
1266.36
nmol/l
1.23
94
336
224
1244
4.22
27.43
9.0
6.5
61.62
57.32
%
5.04
219
1188
195
993
3.79
27.10
7.3
3.5
34.66
84.33
ng/l
0.45
180
744
214
1163
3.98
26.80
5.3
2.8
322.59
138.88
ug/l
2.63
207
1089
80
228
4.43
26.10
14.0
8.6
—
—
—
0
0
143
619
3.52
25.21
4.4
2.5
5.87
4.50
e6/l
0.68
131
565
79
231
4.29
24.82
2.6
2.9
64.13
66.21
g/l
0.99
69
215
35
51
7.64
23.44
2.3
2.2
7.77
5.87
pmol/l
0.76
35
51
90
300
3.87
23.44
7.8
5.3
35.05
43.24
ug/l
0.10
80
251
132
572
3.35
22.76
8.0
3.2
2.45
2.46
mmol/l
0.14
120
525
73
219
4.09
21.95
5.2
3.8
—
—
—
0
0
81
263
3.86
21.77
5.2
5.2
1.29
0.75
%
1.24
46
93
59
154
4.53
21.29
8.0
4.6
—
—
—
0
0
57
146
4.59
21.06
15.6
10.2
14.48
15.93
%
3.09
57
139
283
2061
8.41
20.03
24.9
8.8
101.10
80.46
u/l
4.07
283
1945
171
911
3.06
19.93
5.4
3.2
99.34
113.81
e6/l
0.06
145
708
32
51
6.91
19.71
1.7
2.3
0.85
0.99
%
0.62
26
37
207
1241
3.19
19.28
4.7
2.8
—
—
estimate
—
0
0
153
787
2.94
18.67
4.1
3.1
1.06
0.48
e6/l
0.85
126
584
74
249
3.62
18.64
5.3
5.4
0.33
0.10
%
1.46
39
79
74
252
3.58
18.27
5.0
5.2
1.12
0.43
%
2.57
42
86
197
1175
3.00
18.02
3.4
2.0
84.40
97.20
pmol/l
3.96
151
613
46
112
4.67
17.99
2.5
1.7
0.59
0.38
mg/l
1.05
28
48
84
313
3.34
17.97
3.0
3.1
14.11
8.07
umol/l
0.62
75
282
62
190
3.86
17.87
1.5
2.7
—
—
—
0
0
178
1013
2.88
17.65
6.3
3.8
145.00
90.20
e6/l
0.61
149
733
154
815
2.84
17.51
4.1
3.1
2471.02
1087.71
ng/l
4.13
144
687
73
253
3.50
17.49
5.3
5.9
0.00
0.11
%
1.05
37
71
116
529
2.95
17.44
2.1
1.8
491.88
436.41
pmol/l
0.70
98
441
218
1400
3.08
16.93
5.9
3.6
0.00
0.00
estimate
-0.00
83
290
125
602
2.85
16.88
8.0
5.2
—
—
—
0
0
158
862
2.77
16.72
4.2
2.4
—
—
—
0
0
218
1408
3.04
16.60
6.0
3.6
0.00
0.00
estimate
-0.00
81
300
40
94
4.76
16.28
5.4
3.8
217.73
268.58
mg/l
0.29
27
45
72
259
3.35
16.17
1.7
1.4
—
—
—
0
0
84
332
3.13
16.12
1.5
1.4
—
—
—
0
0
46
125
4.17
15.56
7.9
3.4
—
—
—
0
0
217
1427
2.92
15.43
6.1
3.6
0.00
1.07
estimate
0.50
79
284
70
257
3.25
15.13
2.6
2.9
9.99
10.82
g/l
0.83
63
240
59
197
3.49
14.82
1.9
1.7
1.02
1.23
g/l
0.87
54
182
116
568
2.71
14.81
1.4
1.3
1.12
1.42
u/ml
0.23
31
152
251
1809
3.46
14.73
8.3
4.2
—
2.91
—
0
5
161
929
2.59
14.62
4.6
3.1
6.81
7.99
mmol/l
3.18
133
764
148
823
2.59
14.49
5.7
3.8
0.00
0.00
estimate
-0.00
71
279
159
918
2.57
14.34
5.7
3.8
16.31
5.54
mg/mmol
2.45
115
543
38
95
4.44
14.29
1.3
4.2
52.78
99.78
mg/l
0.34
32
80
38
95
4.44
14.29
1.3
4.2
46.56
33.49
mg/l
1.50
31
83
25
44
6.11
13.92
3.0
2.7
5.27
4.25
e9/l
0.79
25
44
242
1731
3.12
13.91
7.2
3.3
111.02
50.96
u/l
6.18
237
1629
155
895
2.53
13.83
4.6
3.3
93.59
32.98
mg/l
2.89
116
552
108
529
2.63
13.58
1.9
1.5
3.01
2.71
g/l
0.64
78
328
188
1197
2.55
13.45
37.2
11.6
0.01
0.00
e9/l
0.34
169
988
31
69
4.90
13.41
1.3
4.2
—
—
—
0
0
26
28
10.06
13.27
1.3
1.2
33.30
20.15
ng/l
0.49
26
28
131
710
2.51
13.26
4.6
3.0
371.91
348.66
umol/l
1.26
115
622
84
371
2.76
12.88
2.0
1.9
—
—
—
0
0
70
283
2.93
12.64
1.8
1.6
—
—
—
0
0
12
0
+∞
12.59
1.5
0.0
—
—
—
0
0
135
758
2.43
12.46
5.9
2.9
0.00
0.11
estimate
0.50
72
236
23
43
5.71
12.02
2.0
2.6
32.78
31.51
pg
0.43
23
43
82
371
2.67
11.90
1.5
1.3
—
—
—
0
0
77
340
2.71
11.71
1.8
1.6
—
—
—
0
0
39
115
3.75
11.70
1.8
1.3
—
—
—
0
0
23
45
5.45
11.46
3.4
2.2
—
—
—
0
0
120
660
2.37
11.38
5.0
2.4
—
—
—
0
0
22
43
5.44
10.96
14.6
8.3
11.50
11.14
mmol/l
0.16
22
37
22
43
5.44
10.96
14.6
8.3
103.23
105.27
mmol/l
0.66
22
37
27
64
4.54
10.80
3.4
2.6
66.00
57.31
%
2.04
27
64
167
1082
2.24
10.46
6.2
3.5
0.00
0.01
estimate
0.74
77
244
32
90
3.86
10.24
1.3
3.6
1.13
1.66
ratio
1.04
21
55
104
560
2.32
10.16
1.7
1.7
1.70
1.70
mg/l
0.00
87
442
42
143
3.25
10.09
7.6
2.0
0.66
0.62
%
0.32
42
143
54
213
2.87
10.07
2.2
2.4
6.40
8.72
ug/l
0.64
42
194
15
9
17.46
9.98
1.5
1.2
163.93
165.74
mmol/24h
—
15
9
42
144
3.23
9.97
7.6
2.0
1.63
1.27
%
0.65
42
144
79
380
2.47
9.92
1.3
1.4
244.00
525.33
titre
2.42
20
90
164
1086
2.13
9.35
4.8
3.3
6.33
6.18
ph
0.92
86
604
27
74
3.91
8.94
1.1
1.8
—
—
—
0
0
246
1949
2.50
8.53
6.1
4.0
15.65
14.92
pmol/l
3.62
227
1770
31
98
3.41
8.35
1.5
1.5
—
—
—
0
0
237
1865
2.32
8.05
6.6
4.2
—
0.00
—
0
5
87
480
2.15
7.71
7.4
3.8
355.24
467.84
ng/l
0.19
76
375
69
354
2.24
7.29
2.2
1.5
—
—
—
0
0
11
7
16.24
7.28
1.7
1.7
36.91
33.00
%
—
11
7
15
21
7.46
6.79
3.3
2.8
1.01
2.29
mmol/l
0.45
15
21
18
33
5.73
6.72
1.9
1.3
15.69
15.21
ug/l
0.05
18
33
18
34
5.56
6.58
1.6
1.4
414.75
1371.70
e6/l
1.46
12
20
44
195
2.47
6.44
1.8
1.5
—
—
—
0
0
12
14
8.88
6.11
2.4
6.9
13.41
15.66
%
0.68
12
14
287
2564
4.23
6.09
59.9
15.5
30.03
25.01
mg/l
2.20
276
2075
18
50
3.77
5.85
1.8
1.7
5.81
3.74
iu/l
—
7
18
17
35
5.09
5.84
5.9
1.7
11.53
10.40
mmol/l
0.58
17
35
150
1073
1.80
5.83
2.5
2.2
—
—
—
0
0
49
240
2.25
5.72
4.4
2.9
38.73
31.50
u/l
0.29
41
206
14
24
6.07
5.60
1.1
1.2
97.71
102.63
pmol/l
0.11
14
24
58
312
2.07
5.34
3.1
2.1
217.83
105.70
ug/g
2.63
48
244
14
26
5.59
5.29
1.6
1.3
—
—
—
0
0
41
193
2.30
5.24
1.2
1.2
—
—
—
0
0
14
27
5.39
5.15
1.5
1.5
—
—
—
0
0
12
19
6.53
5.13
1.6
2.0
881.17
1784.95
mg
0.42
12
19
18
55
3.42
5.11
2.1
1.7
—
—
—
0
0
11
16
7.09
5.00
2.1
6.1
7.37
6.91
mmol/l
0.23
11
16
15
41
3.80
4.99
1.5
1.9
—
—
—
0
0
15
41
3.80
4.99
1.5
1.9
—
—
—
0
0
15
41
3.80
4.99
1.5
1.9
—
—
—
0
0
15
41
3.80
4.99
1.5
1.9
—
—
—
0
0
63
360
1.95
4.88
4.5
2.9
4.84
4.84
e9/l
0.00
52
319
117
811
1.73
4.83
15.4
6.0
—
—
—
0
0
12
21
5.91
4.80
2.8
2.1
38.17
33.01
%
0.55
12
21
174
2101
0.59
4.69
73.4
19.7
330.76
332.39
g/l
1.38
174
2092
14
32
4.54
4.50
1.6
1.4
7021.29
31725.08
e6/l
—
7
13
49
265
2.02
4.42
21.1
4.1
7.40
7.34
ph
2.64
42
187
9
12
7.69
4.38
5.2
1.9
147.44
126.20
ng/l
—
9
12
12
25
4.96
4.23
1.2
1.3
—
—
—
0
0
12
26
4.76
4.10
1.1
1.0
—
—
—
0
0
16
53
3.13
4.03
2.1
3.3
—
—
—
0
0
12
27
4.59
3.98
1.1
1.1
—
—
—
0
0
13
32
4.20
3.95
1.5
1.6
—
—
—
0
0
107
759
1.64
3.89
1.8
1.4
—
—
—
0
0
71
451
1.75
3.89
4.4
3.0
4.55
1.30
e6/l
1.27
37
230
15
49
3.17
3.86
1.1
1.1
—
—
—
0
0
265
2374
2.05
3.79
7.6
4.8
2.10
1.94
mu/l
0.65
252
2159
12
29
4.27
3.74
1.3
1.4
—
—
nmol/l
—
0
0
13
34
3.95
3.74
1.6
1.9
—
—
—
0
0
25
110
2.39
3.73
1.1
1.1
—
—
—
0
0
7
9
7.93
3.57
1.4
1.2
—
—
—
0
0
13
36
3.73
3.54
3.4
3.9
—
—
—
0
0
16
58
2.86
3.48
1.6
1.4
—
—
—
0
0
41
229
1.92
3.37
3.6
3.2
—
—
—
0
0
8
15
5.45
3.21
4.8
3.7
89.13
69.13
nmol/l
—
8
15
17
67
2.63
3.18
3.5
1.7
58.94
64.24
%
0.46
17
67
17
67
2.63
3.18
3.4
2.6
508.14
115.05
ug/min
—
7
39
28
140
2.10
3.12
1.8
1.8
—
—
—
0
0
12
39
3.16
2.80
1.7
1.6
—
—
—
0
0
283
2650
2.35
2.77
53.7
13.8
—
—
—
0
0
5
6
8.45
2.76
1.2
1.0
80.00
60.83
nmol/24h
—
5
6
6
10
6.10
2.71
1.8
1.7
90.83
64.29
ug/l
—
6
10
8
19
4.30
2.69
1.0
1.0
—
—
—
0
0
13
49
2.73
2.66
1.1
1.0
—
—
—
0
0
10
30
3.41
2.63
1.0
1.0
—
—
—
0
0
7
15
4.75
2.61
1.3
1.1
127.71
131.53
nmol/l
—
7
15
16
68
2.43
2.60
1.6
1.2
—
—
—
0
0
24
123
2.03
2.53
2.8
2.2
0.00
0.03
estimate
—
5
40
7
16
4.45
2.49
1.0
1.0
—
—
—
0
0
9
27
3.40
2.41
1.0
1.1
—
—
—
0
0
7
17
4.19
2.37
1.1
1.1
316.71
363.76
nmol/l
—
7
17
7
17
4.19
2.37
1.3
2.6
1851.29
2325.12
u/ml
—
7
17
9
29
3.17
2.24
1.1
1.7
—
—
—
0
0
8
24
3.40
2.19
1.9
1.2
—
—
—
0
0
56
390
1.54
2.09
1.4
1.3
—
—
—
0
0
9
31
2.96
2.09
1.1
1.2
—
—
—
0
0
13
56
2.38
2.08
1.5
2.2
—
—
—
0
0
21
111
1.96
2.06
2.0
3.0
—
—
—
0
0
13
57
2.34
2.00
1.9
1.5
—
—
—
0
0
13
60
2.22
1.80
1.1
1.1
—
—
—
0
0
12
56
2.19
1.63
5.9
3.7
—
—
—
0
0
37
249
1.55
1.62
2.6
1.9
0.00
0.06
estimate
—
5
54
11
218
0.49
1.58
1.1
1.4
—
—
—
0
0
12
58
2.11
1.51
1.2
1.1
—
—
—
0
0
6
22
2.76
1.44
1.3
1.3
—
—
—
0
0
6
23
2.64
1.37
4.3
2.2
—
—
—
0
0
13
68
1.95
1.35
1.2
1.4
—
—
—
0
0
5
18
2.81
1.29
1.0
1.1
7.52
7.38
ph
—
5
8
8
35
2.32
1.28
1.8
1.7
—
—
—
0
0
8
38
2.14
1.19
1.4
1.1
—
—
—
0
0
0
35
0.00
1.16
0.0
1.1
—
—
—
0
0
98
1137
0.79
1.07
2.2
1.9
1.43
1.31
mmol/l
1.03
76
938
7
37
1.91
0.94
1.1
1.2
—
—
—
0
0
7
127
0.54
0.90
1.3
1.1
—
—
—
0
0
6
29
2.09
0.90
1.3
1.1
—
—
—
0
0
13
79
1.68
0.89
1.5
1.2
—
—
—
0
0
15
95
1.61
0.89
2.0
2.2
20.40
20.98
s
0.18
15
88
73
615
1.25
0.86
7.3
3.8
1.02
1.02
kg/l
0.96
53
393
6
32
1.89
0.82
1.0
1.4
—
—
—
0
0
6
33
1.83
0.79
1.2
1.1
—
—
—
0
0
5
25
2.02
0.73
4.4
2.4
1.16
1.19
mmol/l
—
5
25
5
25
2.02
0.73
1.0
2.0
—
—
—
0
0
5
26
1.94
0.71
2.8
1.5
—
—
—
0
0
254
2622
0.79
0.70
6.3
5.7
2.33
2.71
mmol/l
7.59
228
2418
5
27
1.87
0.68
4.4
2.3
3.94
4.04
mmol/l
—
5
27
5
27
1.87
0.68
4.4
2.3
101.40
105.22
mmol/l
—
5
27
7
43
1.64
0.67
2.7
1.3
—
—
—
0
0
5
29
1.74
0.64
1.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.8
—
—
—
0
0
8
53
1.52
0.59
2.5
1.3
—
—
—
0
0
5
90
0.55
0.56
1.2
1.6
—
—
—
0
0
15
107
1.42
0.56
3.2
1.7
—
—
—
0
0
261
2536
1.24
0.55
6.8
5.1
6.38
5.93
mmol/l
5.09
243
2317
6
39
1.55
0.53
1.3
1.4
—
116.66
—
0
5
128
1184
1.14
0.51
4.9
5.9
1.89
2.67
ug/l
1.18
106
1066
251
2578
0.83
0.50
5.6
4.9
1.41
1.46
mmol/l
1.06
223
2376
8
56
1.44
0.43
2.5
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
11
79
1.41
0.41
1.1
1.2
—
2.25
—
0
11
253
2588
0.85
0.40
5.7
5.1
4.29
4.61
mmol/l
4.15
227
2395
8
60
1.34
0.40
2.5
1.3
—
—
—
0
0
8
60
1.34
0.40
2.5
1.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.8
—
—
—
0
0
8
61
1.32
0.40
2.5
1.3
—
—
—
0
0
33
281
1.20
0.38
2.3
2.4
11.69
13.90
nmol/l
0.92
28
259
44
498
0.86
0.36
1.3
1.3
41.82
38.05
iu/ml
0.08
12
146
16
126
1.29
0.36
6.1
2.8
1.02
1.02
ratio
0.44
16
115
12
91
1.33
0.34
25.1
10.0
—
—
—
0
0
6
87
0.68
0.33
1.5
1.2
—
—
—
0
0
67
725
0.90
0.28
2.9
3.4
1.28
0.75
ug/l
0.40
46
504
8
66
1.22
0.27
1.0
1.4
—
267.16
miu/ml
—
0
29
255
2507
1.12
0.24
9.8
6.1
40.94
38.91
mmol/mol
2.32
238
2333
0
11
0.00
0.21
0.0
1.2
—
0.19
—
0
5
0
10
0.00
0.21
0.0
1.3
—
28.60
—
0
10
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
15
126
1.20
0.21
2.3
2.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
4.8
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
10
122
0.81
0.19
1.2
1.3
—
—
—
0
0
96
1000
0.94
0.16
3.5
3.0
—
—
—
0
0
43
453
0.94
0.10
1.3
1.3
24.63
16.69
u/ml
0.15
15
174
18
197
0.91
0.10
1.2
1.4
—
—
—
0
0
16
176
0.90
0.09
1.1
1.3
—
—
—
0
0
15
137
1.10
0.07
1.3
1.3
68.40
157.13
u/ml
—
5
52
7
83
0.84
0.07
1.0
1.1
—
—
—
0
0
26
272
0.95
0.05
1.3
1.5
—
—
—
0
0
22
230
0.95
0.03
3.1
2.2
6.18
6.01
ph
0.25
17
154
27
260
1.04
0.03
1.6
1.6
—
—
—
0
0
248
2470
1.02
0.02
5.0
4.2
1.52
1.24
mmol/l
6.04
217
2268
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
108.20
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
69.33
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
0.02
—
0
6
0
9
0.00
-0.00
0.0
3.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.8
—
5.70
—
0
5
0
5
0.00
-0.00
0.0
6.2
—
9.24
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint E4_MG_MET and mortality.

Females

Parameter HR [95% CI] p-value
E4_MG_MET 6.28 [3.89, 10.13] < 0.001
Birth year 0.996 [0.99, 1.0] 0.391

During the follow-up period (1.1.1998 — 31.12.2019), 185 out of 478 females with E4_MG_MET died.

Males

Parameter HR [95% CI] p-value
E4_MG_MET 8.216 [5.17, 13.05] < 0.001
Birth year 0.984 [0.97, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 237 out of 529 males with E4_MG_MET died.

Mortality risk

Mortality risk for people of age

years, who have E4_MG_MET.

N-year risk Females Males
1 0.659% 1.418%
5 3.779% 8.106%
10 8.898% 19.789%
15 16.579% 34.075%
20 28.077% 50.984%

Relationships between endpoints

↥

Index endpoint: E4_MG_MET – Disorders of magnesium metabolism

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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