No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
175 |
4. Check minimum number of eventsNone |
175 |
5. Include endpointsNone |
175 |
6. Filter based on genotype QC (FinnGen only) |
157 |
Control definitions (FinnGen only)
- Control exclude
- P16_OTH_DISORD_ORIGINA_PERINA_PERIOD
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- P9
- Name in latin
- Perturbationes nutriendi neonati
Similar endpoints
↥List of similar endpoints to
Feeding problems of newborn
based on the number of shared cases.
Similar with more cases:
- Other disorders originating in the perinatal period
- Certain conditions originating in the perinatal period
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 11115 | 5468 | 5644 |
| Only index persons | 3886 | 2007 | 1879 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.16 | 0.16 | 0.16 |
| Only index persons | 0.07 | 0.07 | 0.07 |
| Median age at first event (years) | |||
| Whole population | 0.05 | 0.04 | 0.04 |
| Only index persons | 0.05 | 0.05 | 0.04 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 157 | 107 | 50 |
| Unadjusted period prevalence (%) | 0.03 | 0.04 | 0.02 |
| Median age at first event (years) | 0.16 | 0.21 | 0.04 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 170
- Matched controls
- 1700
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
P92.5
ICD-10 Finland
Neonatal difficulty in feeding at breast
887.1
64.3
59
*
P92.9
ICD-10 Finland
Feeding problem of newborn, unspecified
+∞
27.9
26
*
P92.3
ICD-10 Finland
Underfeeding of newborn
+∞
25.7
24
*
P92.0
ICD-10 Finland
Vomiting in newborn
145.5
24.3
25
*
P92.1
ICD-10 Finland
Regurgitation and rumination in newborn
97.2
23.4
25
*
P92.2
ICD-10 Finland
Slow feeding of newborn
+∞
15.9
15
*
Z37.0
ICD-10 Finland
Single live birth
4.4
11.1
31
82
A03FA02
ATC
cisapride; oral, rectal
7.6
7.2
16
23
P07.3
ICD-10 Finland
Other preterm infants
3.9
6.5
20
56
MA3AE
NOMESCO Finland
Combined first trimester screening
2.9
6.2
33
131
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
2.9
6.2
33
131
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
33
96
4.02
10.37
1.6
1.6
—
—
—
0
0
33
101
3.81
9.63
1.6
1.6
0.92
0.93
ratio
0.06
16
65
33
101
3.81
9.63
1.6
1.6
1.08
1.08
ratio
0.00
16
65
33
101
3.81
9.63
1.6
1.6
0.83
1.28
ratio
2.62
16
65
33
114
3.35
7.97
1.8
1.6
45.38
60.10
ug/l
1.95
22
99
21
60
3.85
6.68
3.2
2.1
1.02
1.02
ratio
0.52
21
54
10
18
5.83
4.04
1.0
1.1
0.60
0.73
u/ml
—
10
18
40
212
2.16
4.03
1.6
1.6
1052.61
970.56
mu/l
0.18
21
191
75
500
1.89
3.97
5.2
4.9
0.09
0.27
e6/l
1.27
48
365
56
346
1.92
3.69
2.5
3.5
—
—
—
0
0
54
336
1.89
3.45
3.6
4.3
0.47
0.53
e6/l
0.13
29
186
53
334
1.85
3.23
3.6
4.6
0.98
1.67
e6/l
0.58
28
184
76
542
1.73
3.02
5.5
5.4
—
—
—
0
0
94
732
1.64
2.54
11.6
15.3
1.23
1.23
mmol/l
0.11
89
679
100
804
1.59
2.28
6.3
9.6
6.09
5.87
mmol/l
0.17
90
748
73
550
1.57
2.17
3.8
3.7
—
—
estimate
—
0
0
6
18
3.42
1.76
3.3
2.6
67.83
67.39
umol/l
—
6
18
5
13
3.93
1.72
2.0
1.1
—
—
—
0
0
46
331
1.53
1.61
2.5
2.4
—
—
—
0
0
29
194
1.60
1.39
3.0
8.6
6.26
7.54
umol/l
0.18
24
159
24
153
1.66
1.38
1.6
2.3
8.25
7.31
iu/l
0.10
14
91
0
39
0.00
1.35
0.0
1.2
—
—
—
0
0
6
24
2.55
1.31
10.3
7.8
4.73
5.61
pmol/l
—
6
24
86
721
1.39
1.31
5.0
3.9
0.00
0.00
estimate
-0.00
13
124
50
381
1.44
1.31
8.1
12.2
0.54
1.03
mmol/l
0.82
33
279
9
44
2.10
1.29
1.7
1.5
—
—
—
0
0
39
284
1.48
1.29
2.6
2.2
—
—
—
0
0
6
25
2.45
1.25
1.0
1.0
—
—
—
0
0
91
775
1.37
1.24
3.0
3.1
1.08
1.05
mmol/l
0.18
91
739
85
717
1.37
1.22
4.5
3.9
0.00
0.00
estimate
-0.00
14
123
28
196
1.51
1.11
2.5
2.7
11800.89
5731.38
u/l
0.41
12
73
19
122
1.63
1.08
1.8
1.9
—
—
—
0
0
83
712
1.32
1.02
4.6
3.9
0.00
0.00
estimate
-0.00
14
126
53
426
1.35
1.00
10.6
18.0
24.43
24.69
mmol/l
0.36
53
426
5
23
2.21
0.98
1.0
1.7
—
—
—
0
0
9
50
1.84
0.98
1.3
1.6
—
—
—
0
0
59
485
1.33
0.96
7.6
9.6
24.70
25.97
umol/l
0.07
54
455
23
161
1.50
0.92
1.7
2.2
5.33
6.49
u/l
0.45
12
87
5
104
0.47
0.92
1.4
1.7
—
—
—
0
0
6
31
1.97
0.85
2.3
1.3
—
—
—
0
0
21
147
1.49
0.85
2.0
2.1
—
—
—
0
0
21
147
1.49
0.85
2.0
2.1
—
—
—
0
0
31
235
1.39
0.84
1.1
1.1
—
—
—
0
0
6
32
1.91
0.82
1.0
1.0
1.30
1.55
g/l
—
6
32
6
32
1.91
0.82
1.2
1.0
0.66
0.75
g/l
—
6
32
18
123
1.52
0.81
6.9
4.3
26.68
128.09
mg/mmol
0.41
13
97
6
33
1.85
0.80
2.2
1.4
—
—
—
0
0
21
150
1.46
0.78
8.7
16.1
106.05
105.55
mmol/l
0.23
21
150
12
75
1.65
0.77
1.9
1.6
—
—
—
0
0
95
852
1.26
0.75
3.3
3.2
2.47
2.60
mmol/l
0.88
95
810
17
117
1.50
0.75
1.1
1.2
4.84
7.05
u/ml
0.37
11
91
14
92
1.57
0.75
2.6
5.2
4.56
12.88
umol/l
2.04
14
78
88
785
1.25
0.72
7.2
6.1
129.99
126.19
u/l
0.14
82
739
47
389
1.29
0.72
7.0
11.7
1.13
0.90
mmol/l
0.29
38
312
5
26
1.95
0.71
1.0
1.5
—
—
—
0
0
10
61
1.68
0.70
1.1
1.2
—
—
—
0
0
95
858
1.24
0.69
3.3
3.4
4.21
4.35
mmol/l
0.93
95
822
41
336
1.29
0.67
1.6
1.8
87.23
93.43
pmol/l
0.38
24
173
11
71
1.59
0.64
2.4
2.3
—
—
—
0
0
5
30
1.69
0.62
2.8
1.3
—
—
—
0
0
0
22
0.00
0.59
0.0
1.0
—
92.14
—
0
14
8
53
1.53
0.59
2.0
1.4
—
—
—
0
0
0
23
0.00
0.58
0.0
1.3
—
92.67
—
0
15
10
67
1.52
0.51
1.6
1.5
—
—
—
0
0
15
110
1.40
0.51
1.1
1.2
32.41
12.11
u/ml
—
8
81
53
465
1.20
0.48
4.2
3.2
0.00
0.01
estimate
0.50
13
100
23
183
1.30
0.48
2.2
2.0
—
—
—
0
0
5
84
0.58
0.47
1.6
1.3
—
—
—
0
0
7
50
1.42
0.45
2.1
2.0
—
—
—
0
0
5
31
1.63
0.43
1.0
1.0
37.40
31.38
iu/ml
—
5
31
13
96
1.38
0.43
1.0
1.0
10.75
8.59
mu/l
0.50
13
89
41
355
1.20
0.43
12.8
13.6
1.35
1.36
mmol/l
0.07
41
340
8
58
1.40
0.42
3.0
3.3
10.38
10.53
%
—
8
58
8
58
1.40
0.42
3.0
3.3
—
—
—
0
0
5
33
1.53
0.41
1.0
1.2
—
1.48
—
0
21
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
14
106
1.35
0.40
1.1
1.1
0.11
1.47
u/ml
—
8
68
79
727
1.16
0.40
2.2
1.9
3.41
4.09
u/ml
0.13
14
113
100
937
1.16
0.40
4.1
5.0
6.36
7.35
mm/h
0.70
100
889
0
19
0.00
0.39
0.0
1.6
—
—
—
0
0
17
134
1.30
0.38
1.4
1.5
—
—
—
0
0
5
36
1.40
0.38
1.0
1.5
80.80
75.58
%
—
5
36
50
446
1.17
0.37
3.3
2.6
—
—
—
0
0
165
1623
1.57
0.36
20.5
19.8
4.53
4.55
e12/l
0.22
160
1556
87
811
1.15
0.36
2.5
2.2
—
—
—
0
0
83
772
1.15
0.36
13.6
7.5
110.94
111.02
ml/min/173m2
0.01
65
579
38
336
1.17
0.32
4.2
3.2
0.00
0.00
estimate
-0.00
13
101
7
53
1.33
0.31
2.1
2.1
—
—
—
0
0
150
1463
1.21
0.30
14.6
13.0
24.43
22.13
mg/l
0.41
118
1078
10
129
0.76
0.29
1.3
1.3
—
—
—
0
0
10
77
1.32
0.26
1.9
2.0
—
—
—
0
0
8
67
1.20
0.26
7.5
2.6
—
—
—
0
0
9
77
1.18
0.25
1.6
1.8
1.14
1.15
g/l
—
9
72
15
125
1.22
0.23
2.0
2.3
184.23
193.18
u/ml
—
10
53
15
178
0.83
0.23
2.3
4.1
1013.20
1050.76
ng/l
—
5
98
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.9
—
—
—
0
0
0
13
0.00
0.21
0.0
1.8
—
0.05
—
0
8
6
50
1.21
0.20
1.2
2.3
—
—
—
0
0
21
185
1.15
0.19
4.3
5.4
0.21
0.20
g/l
0.14
21
180
18
157
1.16
0.18
10.0
20.9
1.67
1.43
mmol/l
0.41
18
151
7
62
1.13
0.17
14.9
29.9
0.56
0.70
%
—
7
62
149
1465
1.14
0.17
4.6
4.1
—
—
—
0
0
8
68
1.19
0.17
2.0
2.1
—
—
—
0
0
8
69
1.17
0.16
13.5
26.7
23.75
24.06
mmol/l
—
8
69
8
72
1.12
0.16
2.0
2.3
—
—
—
0
0
9
81
1.12
0.15
1.0
1.0
3.70
3.41
kpa
—
9
73
9
81
1.12
0.15
1.0
1.0
19.56
19.71
mmol/l
—
9
81
9
82
1.10
0.15
1.0
1.0
6.44
7.14
kpa
—
9
74
9
82
1.10
0.15
12.1
23.2
0.33
-0.03
mmol/l
—
9
73
7
88
0.79
0.15
1.3
1.5
44.96
58.80
ug/l
—
7
88
7
90
0.77
0.15
1.4
1.8
—
—
—
0
0
19
171
1.13
0.13
1.9
1.5
1.29
1.37
%
0.46
19
153
11
96
1.16
0.10
2.7
3.4
5.06
5.19
pmol/l
0.20
11
87
37
351
1.07
0.09
2.5
2.9
1.17
1.02
kg/l
0.49
30
232
19
175
1.10
0.09
1.2
1.2
1.47
2.26
u/ml
0.27
14
144
5
63
0.79
0.08
1.2
1.5
—
—
—
0
0
5
63
0.79
0.08
1.2
1.5
—
—
—
0
0
7
63
1.12
0.08
15.3
29.5
0.97
0.94
%
—
7
63
22
206
1.08
0.07
1.8
1.4
—
—
—
0
0
15
139
1.09
0.05
1.1
1.5
—
—
—
0
0
11
120
0.91
0.05
5.4
5.0
25.57
24.08
nmol/l
0.13
11
120
103
1016
1.03
0.05
8.7
11.9
3.62
3.46
e9/l
0.24
83
846
15
140
1.08
0.04
2.2
8.4
3.32
2.81
g/l
0.36
15
134
16
151
1.07
0.03
2.4
10.4
97.63
91.77
%
0.61
16
151
14
132
1.07
0.02
1.3
1.3
—
—
—
0
0
43
421
1.03
0.02
3.1
2.5
—
—
—
0
0
20
192
1.05
0.02
1.2
1.3
0.25
2.95
u/ml
2.41
15
155
11
104
1.06
0.01
1.3
1.1
—
51.76
—
0
9
18
174
1.04
0.00
1.2
1.3
0.16
0.95
u/ml
1.43
13
140
25
256
0.97
0.00
1.7
5.5
1.28
1.36
mg/l
0.08
20
182
34
335
1.02
0.00
5.0
3.7
0.00
0.00
estimate
-0.00
14
116
17
175
0.97
0.00
2.2
2.7
8.78
12.18
ng/l
—
9
58
18
175
1.03
0.00
1.2
1.3
0.90
5.94
u/ml
3.74
13
146
15
152
0.99
0.00
4.3
7.4
260.40
267.37
umol/l
0.10
15
143
10
95
1.06
0.00
2.1
2.1
4.03
6.87
nmol/l
—
10
85
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
8
79
1.01
0.00
2.3
1.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
5
56
0.89
0.00
1.2
2.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
87.29
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
-0.00
1.2
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
70.54
—
0
5
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
51
0.98
-0.00
1.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
70.00
—
0
7
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint P16_FEEDI_PROBL_NEWBO and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have P16_FEEDI_PROBL_NEWBO.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: P16_FEEDI_PROBL_NEWBO – Feeding problems of newborn
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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