No definition available.
Other disorders originating in the perinatal period
P16_OTH_DISORD_ORIGINA_PERINA_PERIOD
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
393 |
4. Check minimum number of eventsNone |
393 |
5. Include endpoints |
393 |
6. Filter based on genotype QC (FinnGen only) |
353 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 2
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- P
- Name in latin
- Aliae morbositates origine perinatales
Other disorders originating in the perinatal period
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 19070 | 9095 | 9959 |
| Only index persons | 8108 | 4005 | 4103 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.27 | 0.26 | 0.28 |
| Only index persons | 0.15 | 0.15 | 0.16 |
| Median age at first event (years) | |||
| Whole population | 0.08 | 0.03 | 0.03 |
| Only index persons | 0.04 | 0.06 | 0.03 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 353 | 229 | 124 |
| Unadjusted period prevalence (%) | 0.07 | 0.08 | 0.06 |
| Median age at first event (years) | 2.76 | 4.22 | 0.06 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 374
- Matched controls
- 3740
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
P95
ICD-10 Finland
Fetal death of unspecified cause
+∞
64.5
60
*
P92.5
ICD-10 Finland
Neonatal difficulty in feeding at breast
695.0
61.6
59
*
P94.2
ICD-10 Finland
Congenital hypotonia
124.3
32.2
34
*
P92.9
ICD-10 Finland
Feeding problem of newborn, unspecified
+∞
27.4
26
*
P92.3
ICD-10 Finland
Underfeeding of newborn
+∞
25.3
24
*
P90
ICD-10 Finland
Convulsions of newborn
+∞
24.2
23
*
P92.0
ICD-10 Finland
Vomiting in newborn
133.6
23.9
25
*
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
8.1
23.7
33
44
P92.1
ICD-10 Finland
Regurgitation and rumination in newborn
89.1
23.0
25
*
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
4.8
19.6
48
112
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.0
19.4
61
173
P85
ICPC
Mental retardation
7.1
18.6
29
44
P07.3
ICD-10 Finland
Other preterm infants
4.6
16.2
41
98
O36.4
ICD-10 Finland
Maternal care for intrauterine death
62.8
15.9
18
*
P92.2
ICD-10 Finland
Slow feeding of newborn
+∞
15.7
15
*
G02CB01
ATC
bromocriptine; systemic
14.8
15.2
25
18
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
3.6
14.9
55
173
P94.1
ICD-10 Finland
Congenital hypertonia
+∞
14.7
14
*
R62.0
ICD-10 Finland
Delayed milestone
3.4
13.5
54
179
R4110
NOMESCO Finland
Physiotherapy
2.3
13.1
136
736
G80.0
ICD-10 Finland
Spastic quadriplegic cerebral palsy
67.1
11.7
13
*
P91.02
ICD-10 Finland
Neonatal hypoxic-ischaemic encephalopathy, severe
+∞
11.5
11
*
A03FA02
ATC
cisapride; oral, rectal
4.5
11.2
28
66
P21.0
ICD-10 Finland
Severe birth asphyxia
29.0
10.8
14
5
R62.8
ICD-10 Finland
Other lack of expected normal physiological development
5.7
10.5
20
37
P96.0
ICD-10 Finland
Congenital renal failure
+∞
10.5
10
*
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
11.1
10.4
19
18
NE1AA
NOMESCO Finland
Pelvis X-ray examination
4.8
10.4
24
53
G80.9
ICD-10 Finland
Cerebral palsy, unspecified
33.6
10.4
13
*
H50.30
ICD-10 Finland
Intermittent esotropy
5.1
10.4
22
45
Z39.2
ICD-10 Finland
Routine postpartum follow-up
2.4
9.6
80
388
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
7.9
9.5
21
28
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
22.4
9.4
13
6
WX722
NOMESCO Finland
PEEP
3.5
8.7
30
90
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
3.1
8.6
38
133
Z3226
NOMESCO Finland
Physiotherapist
2.1
8.6
109
622
TAW99
NOMESCO Finland
Other minor neurosurgical procedure
20.6
8.5
12
6
G80.8
ICD-10 Finland
Other cerebral palsy
92.1
8.4
9
*
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.3
8.4
75
372
P94.9
ICD-10 Finland
Disorder of muscle tone of newborn, unspecified
+∞
8.4
8
*
P96.8
ICD-10 Finland
Other specified conditions originating in the perinatal period
+∞
8.4
8
*
P91.8
ICD-10 Finland
Other specified disturbances of cerebral status of newborn
+∞
8.4
8
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.1
8.3
98
544
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
2.8
7.9
42
163
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.1
7.8
94
524
RT190, ,
NOMESCO Finland
15.4
7.8
12
8
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
7.7
149
978
F79.9
ICD-10 Finland
Unspecified mental retardation, without mention of impairment of behaviour
12.2
7.6
13
11
Z37.0
ICD-10 Finland
Single live birth
2.6
7.4
46
193
RT490, ,
NOMESCO Finland
9.6
7.3
14
15
Z2446
NOMESCO Finland
Social worker
2.1
7.3
81
437
P91.08
ICD-10 Finland
Acute neonatal cerebral ischaemia
+∞
7.3
7
*
WX930
NOMESCO Finland
Thepapeutic hypothermia
+∞
7.3
7
*
P91.9
ICD-10 Finland
Disturbance of cerebral status of newborn, unspecified
+∞
7.3
7
*
ZXE00
NOMESCO Finland
One hour or less
1.8
7.3
163
1113
N03AX14
ATC
levetiracetam; systemic
3.7
7.3
23
65
P70.4
ICD-10 Finland
Other neonatal hypoglycaemia
4.1
7.3
20
51
P22.1
ICD-10 Finland
Transient tachypnoea of newborn
3.8
7.1
22
61
N05BA09
ATC
clobazam; oral
4.3
7.1
18
43
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.3
6.9
54
253
N18.8
ICD-10 Finland
Other chronic renal failure
8.5
6.9
14
17
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.1
6.8
28
94
RS142, ,
NOMESCO Finland
17.1
6.8
10
6
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.7
6.8
36
140
RL140, ,
NOMESCO Finland
5.7
6.7
18
33
R5140
NOMESCO Finland
Monitoring the use of the aid
3.7
6.7
21
59
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
3.9
6.6
19
50
NF1AA
NOMESCO Finland
Hip X-ray examination
4.1
6.5
18
46
G80.3
ICD-10 Finland
Dyskinetic cerebral palsy
71.0
6.4
7
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.1
6.4
65
339
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
11.3
6.3
11
10
P91.1
ICD-10 Finland
Acquired periventricular cysts of newborn
+∞
6.3
6
*
P94.0
ICD-10 Finland
Transient neonatal myasthenia gravis
+∞
6.3
6
*
P94.8
ICD-10 Finland
Other disorders of muscle tone of newborn
+∞
6.3
6
*
P96.9
ICD-10 Finland
Condition originating in the perinatal period, unspecified
+∞
6.3
6
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
6.2
119
768
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
2.4
6.1
41
179
M03BX01
ATC
baclofen; systemic
8.8
6.1
12
14
RT150, ,
NOMESCO Finland
4.0
6.1
17
44
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
6.0
68
368
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
2.5
6.0
37
155
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
42
168
2.69
7.47
1.6
1.5
—
—
—
0
0
110
667
1.92
7.14
4.4
4.4
1.58
2.02
e6/l
0.36
62
347
42
174
2.59
6.97
1.6
1.5
1.18
1.10
ratio
0.19
22
107
42
174
2.59
6.97
1.6
1.5
0.92
1.26
ratio
1.87
22
107
42
174
2.59
6.97
1.6
1.5
0.90
0.95
ratio
0.30
22
107
109
685
1.83
6.22
4.3
4.0
0.57
0.62
e6/l
0.10
60
363
160
1126
1.74
6.20
6.6
5.1
—
—
—
0
0
147
1024
1.72
5.83
6.1
4.6
0.14
0.29
e6/l
1.39
100
740
42
193
2.32
5.60
1.8
1.6
54.66
58.20
ug/l
0.15
29
169
224
1764
1.67
5.46
8.1
9.8
6.09
6.05
mmol/l
0.06
209
1641
146
1030
1.68
5.44
9.6
9.7
37.26
37.53
g/l
0.21
139
1000
208
1613
1.65
5.33
17.3
14.2
1.22
1.23
mmol/l
0.28
199
1499
160
1215
1.55
4.14
10.2
9.0
23.73
23.90
umol/l
0.02
150
1139
108
751
1.62
4.06
13.9
11.6
0.68
0.79
mmol/l
0.18
77
565
193
1540
1.52
3.91
17.4
16.1
1.23
1.23
mmol/l
0.07
187
1479
59
354
1.79
3.81
8.5
17.5
106.02
105.57
mmol/l
0.30
59
354
29
135
2.24
3.78
1.6
1.5
—
—
—
0
0
110
783
1.57
3.71
9.1
12.0
5.75
5.72
kpa
0.17
105
768
225
1867
1.51
3.71
11.2
6.6
124.00
119.14
u/l
0.37
218
1778
109
777
1.57
3.65
8.9
12.0
1.03
0.82
mmol/l
0.39
90
627
109
779
1.56
3.60
4.7
3.5
—
—
—
0
0
15
52
2.96
3.50
14.5
6.8
9.00
5.22
pmol/l
0.48
15
52
195
1586
1.48
3.44
5.6
3.9
0.00
0.00
estimate
-0.00
29
272
194
1578
1.48
3.41
5.4
3.9
0.03
0.00
estimate
0.49
29
278
106
762
1.55
3.39
8.8
11.8
5.17
5.21
kpa
0.08
101
749
319
2915
1.64
2.92
24.9
15.9
3.96
3.94
mmol/l
0.51
313
2847
5
6
8.42
2.75
1.0
1.0
—
—
—
0
0
188
1568
1.40
2.65
5.5
3.9
0.00
0.00
estimate
-0.00
29
284
53
343
1.64
2.62
2.8
2.3
—
—
—
0
0
6
11
5.52
2.55
2.2
1.2
—
—
—
0
0
6
11
5.52
2.55
2.5
1.2
—
—
—
0
0
62
421
1.57
2.52
2.8
2.2
—
—
—
0
0
154
1251
1.39
2.49
5.0
3.7
—
—
estimate
—
0
0
8
21
3.87
2.47
2.1
1.6
—
—
—
0
0
53
350
1.60
2.42
2.8
2.1
—
—
—
0
0
19
92
2.12
2.31
4.6
4.0
1.33
1.67
umol/l
1.88
19
87
80
586
1.46
2.28
3.2
2.5
253.90
384.31
u/l
0.43
80
570
5
9
5.61
2.22
2.2
1.2
—
—
—
0
0
26
145
1.85
2.17
4.0
3.8
48.90
83.23
ml/min/173m2
—
10
48
66
471
1.49
2.14
18.8
17.0
6.37
5.18
mmol/l
1.28
66
461
37
232
1.66
2.08
10.8
19.2
-0.39
-0.17
mmol/l
0.11
29
198
15
69
2.22
2.07
2.5
2.1
1.93
2.14
mmol/l
—
10
52
16
76
2.15
2.05
2.3
1.2
—
—
—
0
0
22
119
1.90
2.02
1.9
1.9
—
—
—
0
0
52
358
1.53
2.00
1.7
1.6
1140.21
937.19
mu/l
0.47
29
319
61
436
1.48
1.97
3.1
8.0
5.61
6.20
umol/l
0.17
53
366
14
64
2.23
1.97
1.3
1.3
3.20
3.78
u/ml
—
5
32
29
173
1.73
1.96
5.0
4.4
0.14
0.13
e6/l
0.05
29
165
10
39
2.61
1.95
4.0
2.4
0.97
1.08
umol/l
—
10
34
10
39
2.61
1.95
2.7
1.7
—
—
—
0
0
27
158
1.76
1.95
2.0
2.1
—
—
—
0
0
21
115
1.88
1.87
2.1
1.4
—
—
—
0
0
6
17
3.57
1.84
8.0
6.6
238.50
218.53
ug/l
—
6
17
5
12
4.21
1.83
3.6
2.3
104.60
105.75
mmol/l
—
5
12
54
384
1.47
1.79
6.2
4.0
15.73
52.38
mg/mmol
0.41
42
264
20
110
1.86
1.76
2.0
2.5
—
—
—
0
0
27
164
1.70
1.73
2.1
2.3
—
—
—
0
0
14
68
2.10
1.72
2.5
1.5
—
—
—
0
0
20
112
1.83
1.68
1.4
1.2
—
—
—
0
0
10
40
2.54
1.68
1.0
1.1
0.60
0.96
u/ml
—
10
40
15
77
1.99
1.61
1.9
1.5
—
—
—
0
0
8
32
2.53
1.60
1.0
1.3
115.25
115.25
pmol/l
—
8
32
94
751
1.34
1.60
5.1
3.2
13.91
1.02
kg/l
0.50
79
505
21
122
1.76
1.58
1.9
1.9
—
—
—
0
0
7
160
0.43
1.58
1.7
1.3
—
—
—
0
0
8
33
2.45
1.54
9.1
9.4
—
—
—
0
0
50
363
1.44
1.51
1.7
2.2
17.49
14.23
iu/l
0.31
35
242
6
21
2.89
1.51
1.3
1.4
—
—
—
0
0
76
595
1.35
1.48
2.7
5.2
3.75
1.51
mg/l
0.47
63
445
44
313
1.46
1.48
3.6
12.9
91.27
91.45
%
0.02
44
313
26
164
1.63
1.47
1.9
1.9
15.05
20.76
ng/l
2.22
26
164
27
172
1.61
1.47
12.2
24.4
94.04
95.75
%
0.37
27
172
6
22
2.75
1.44
1.0
1.3
—
—
—
0
0
17
97
1.79
1.37
5.3
3.9
2.57
6.57
ug/l
—
9
65
11
54
2.07
1.34
13.0
7.9
5.15
4.92
kpa
0.38
11
54
20
122
1.68
1.30
12.7
13.9
68.67
416.88
iu/ml
—
6
16
5
18
2.80
1.29
1.2
1.3
—
—
—
0
0
10
48
2.11
1.29
1.5
1.5
—
—
—
0
0
26
171
1.56
1.27
12.5
24.5
0.70
0.67
%
0.16
26
171
8
36
2.25
1.25
3.0
2.8
68.12
60.61
umol/l
—
8
36
6
25
2.42
1.25
2.2
1.1
—
—
—
0
0
124
1061
1.25
1.23
5.2
3.2
0.00
0.00
estimate
0.50
25
231
10
49
2.07
1.23
2.9
1.7
—
—
—
0
0
8
37
2.19
1.22
1.3
1.2
—
—
—
0
0
8
37
2.19
1.22
7.8
7.4
—
—
—
0
0
209
1896
1.23
1.20
20.8
8.6
102.31
102.31
ml/min/173m2
0.00
173
1524
14
79
1.80
1.18
4.7
2.1
38.71
40.86
u/l
0.14
14
73
25
166
1.54
1.18
2.4
2.0
—
—
—
0
0
74
597
1.30
1.18
2.3
2.4
—
—
—
0
0
53
408
1.35
1.16
2.6
4.2
349.45
906.46
ng/l
1.71
29
221
40
294
1.40
1.16
1.9
2.4
5.74
6.87
u/l
0.35
24
163
14
80
1.78
1.14
1.7
1.5
—
—
—
0
0
47
361
1.35
1.06
4.2
8.7
885.55
1145.71
ng/l
0.22
41
307
25
172
1.49
1.03
12.5
24.4
1.12
1.02
%
0.43
25
172
9
48
1.90
1.01
1.0
1.0
—
—
—
0
0
7
35
2.02
1.00
2.0
1.5
—
—
—
0
0
264
2484
1.21
0.94
4.5
4.2
14.08
14.43
pmol/l
1.71
254
2309
26
185
1.44
0.92
3.0
2.6
106.33
89.38
au/ml
—
6
82
232
2160
1.20
0.91
13.5
12.6
3.61
3.50
e9/l
0.27
193
1794
333
3218
1.32
0.90
22.0
13.4
22.52
21.54
mg/l
0.26
266
2402
91
779
1.22
0.89
5.2
3.0
0.00
0.00
estimate
0.50
25
227
18
120
1.53
0.87
1.5
1.4
—
—
—
0
0
18
120
1.53
0.87
1.5
1.4
—
—
—
0
0
23
162
1.45
0.86
1.7
1.6
1.13
1.14
g/l
0.05
23
154
63
520
1.25
0.86
2.3
2.2
—
—
—
0
0
19
130
1.49
0.82
1.6
1.9
3.24
3.36
iu/ml
—
5
22
8
47
1.72
0.81
1.3
1.1
—
—
—
0
0
8
47
1.72
0.81
1.8
4.4
0.88
0.53
index
—
8
47
10
163
0.60
0.80
1.6
1.7
—
—
—
0
0
16
106
1.53
0.80
2.1
2.0
—
—
—
0
0
26
191
1.39
0.79
1.3
1.3
202.38
263.69
miu/ml
0.44
13
95
6
33
1.83
0.79
1.0
1.1
—
—
—
0
0
17
115
1.50
0.78
1.2
1.8
—
—
—
0
0
361
3543
1.54
0.77
29.2
20.6
4.50
4.55
e12/l
1.12
352
3397
291
2784
1.20
0.77
5.1
4.8
1.93
1.94
mu/l
0.05
285
2662
28
210
1.36
0.76
5.9
4.9
25.51
23.30
nmol/l
0.31
28
205
5
24
2.10
0.75
2.4
1.1
—
—
—
0
0
22
159
1.41
0.74
1.7
1.6
0.20
0.21
g/l
0.21
22
153
32
248
1.32
0.71
1.8
1.8
—
—
—
0
0
15
101
1.51
0.71
1.4
1.3
335.50
363.52
ug/g
—
8
61
86
752
1.19
0.68
5.9
3.7
0.00
0.00
estimate
-0.00
27
269
23
171
1.37
0.67
3.2
1.8
—
—
—
0
0
29
224
1.32
0.67
1.1
1.2
10.27
7.34
u/ml
0.27
20
162
40
489
0.80
0.66
1.4
1.3
38.78
19.55
iu/ml
—
10
127
360
3539
1.46
0.66
29.4
20.7
272.91
273.08
e9/l
0.02
352
3400
7
44
1.60
0.65
1.1
1.1
—
—
—
0
0
58
491
1.21
0.65
4.6
2.8
21.45
19.46
ng/l
0.11
29
196
157
1449
1.14
0.61
2.0
1.9
3.80
3.65
u/ml
0.03
27
261
5
30
1.68
0.61
1.6
1.2
—
—
—
0
0
9
141
0.63
0.61
1.4
1.5
61.57
56.03
ug/l
—
9
141
10
151
0.65
0.61
1.7
1.8
—
—
—
0
0
42
346
1.24
0.61
2.9
2.4
10385.05
5561.55
u/l
0.38
14
125
0
20
0.00
0.60
0.0
1.9
—
—
—
0
0
106
953
1.16
0.60
3.0
3.6
2.92
2.41
mg/l
1.80
101
866
39
321
1.24
0.57
1.3
1.4
138.67
167.70
u/ml
—
6
109
6
36
1.68
0.57
1.7
1.6
13.00
13.07
%
—
6
36
11
73
1.52
0.57
1.7
1.6
—
—
—
0
0
62
536
1.19
0.57
1.8
1.4
20.55
20.59
nmol/l
0.01
57
478
27
214
1.28
0.54
1.1
1.2
22.61
10.98
u/ml
0.75
16
149
18
134
1.36
0.54
1.5
1.5
—
—
—
0
0
7
46
1.53
0.48
1.0
1.1
41.29
26.82
iu/ml
—
7
46
90
813
1.14
0.48
2.0
1.7
90.87
97.94
pmol/l
0.84
52
423
7
49
1.44
0.46
23.6
1.8
—
—
—
0
0
35
293
1.21
0.46
3.7
2.4
25.71
31.77
u/l
0.94
28
239
20
158
1.28
0.42
5.7
2.8
—
—
—
0
0
6
94
0.63
0.42
1.0
1.1
1.30
1.59
g/l
—
6
94
6
94
0.63
0.42
1.2
1.1
0.66
0.80
g/l
—
6
94
0
15
0.00
0.41
0.0
2.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
17
132
1.30
0.41
1.1
1.2
—
—
—
0
0
72
796
0.88
0.40
2.5
2.5
—
—
—
0
0
25
205
1.24
0.40
1.1
1.1
1.74
1.00
u/ml
0.17
15
124
0
18
0.00
0.40
0.0
1.7
—
—
—
0
0
7
105
0.66
0.40
4.4
1.8
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
5
36
1.39
0.38
4.0
1.4
—
—
—
0
0
9
67
1.35
0.38
1.1
1.1
—
—
—
0
0
6
43
1.40
0.35
1.2
1.1
—
—
—
0
0
40
455
0.86
0.34
1.4
1.2
3.60
5.25
u/ml
0.31
14
163
6
44
1.37
0.34
1.2
1.1
—
—
—
0
0
6
44
1.37
0.34
1.2
1.1
—
—
—
0
0
15
118
1.28
0.34
2.8
3.8
—
—
—
0
0
6
45
1.34
0.34
1.3
1.2
0.05
3.22
u/ml
—
6
38
6
45
1.34
0.34
1.2
1.1
—
—
—
0
0
6
89
0.67
0.33
1.7
1.7
—
—
—
0
0
14
110
1.28
0.32
2.1
2.2
2.15
3.54
iu/l
—
5
48
22
184
1.21
0.31
4.3
16.4
0.75
0.58
%
1.14
22
184
7
54
1.30
0.30
1.0
1.3
0.03
1.93
u/ml
—
7
54
12
93
1.30
0.30
1.2
1.2
—
—
—
0
0
7
55
1.28
0.30
3.7
5.7
—
—
—
0
0
8
65
1.24
0.27
1.0
1.4
86.25
77.31
%
—
8
65
8
67
1.20
0.26
1.0
1.7
—
—
—
0
0
9
73
1.24
0.25
1.4
2.9
1.42
0.84
e9/l
—
9
73
48
437
1.11
0.25
1.1
1.1
—
—
—
0
0
22
191
1.16
0.22
1.0
1.0
-3.01
-2.21
mmol/l
—
8
48
0
11
0.00
0.21
0.0
2.0
—
197.73
—
0
11
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
11
89
1.24
0.21
1.5
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
1.00
—
0
7
13
155
0.83
0.20
8.0
4.8
—
—
—
0
0
6
49
1.23
0.20
1.0
1.9
—
—
—
0
0
11
90
1.23
0.19
1.2
1.2
—
—
—
0
0
17
147
1.16
0.18
1.4
1.6
0.13
0.14
mg/l
—
5
56
26
233
1.12
0.18
1.4
1.5
—
—
—
0
0
5
66
0.75
0.17
1.2
2.3
—
—
—
0
0
23
256
0.89
0.16
1.3
1.3
—
—
—
0
0
26
235
1.11
0.16
2.5
2.3
197.02
172.32
u/ml
0.20
16
108
36
332
1.09
0.16
1.3
1.3
0.89
5.60
u/ml
6.53
24
264
9
78
1.16
0.15
1.1
1.3
—
—
—
0
0
9
83
1.09
0.14
4.8
6.0
1.74
2.05
ug/l
—
9
83
81
842
0.95
0.12
2.7
2.6
—
—
—
0
0
308
3050
1.06
0.12
4.3
4.1
—
—
—
0
0
151
1545
0.96
0.11
2.2
2.1
—
—
—
0
0
25
231
1.09
0.11
1.4
1.5
—
—
—
0
0
35
329
1.07
0.10
1.3
1.3
0.97
0.86
u/ml
0.05
23
247
215
2118
1.04
0.10
3.5
3.0
5.56
5.42
mmol/l
0.71
206
1960
5
44
1.14
0.10
1.2
1.1
—
—
—
0
0
5
46
1.09
0.09
1.0
1.2
—
—
—
0
0
51
488
1.05
0.09
1.7
1.5
—
—
—
0
0
6
54
1.11
0.09
1.2
3.1
13.50
32.16
u/ml
—
6
49
5
63
0.79
0.08
3.4
1.8
—
—
—
0
0
39
372
1.05
0.08
2.1
1.5
1.40
1.36
%
0.17
39
335
24
255
0.94
0.07
1.5
1.6
3.09
3.25
mmol/l
0.26
14
169
37
355
1.05
0.06
1.2
1.3
1.14
2.78
u/ml
0.93
26
275
21
198
1.06
0.05
1.9
1.8
—
—
—
0
0
15
140
1.07
0.04
3.3
4.5
319.87
353.14
mg/l
0.19
15
140
27
264
1.02
0.00
1.4
1.3
—
—
—
0
0
17
172
0.99
0.00
1.7
1.9
—
—
—
0
0
31
309
1.00
0.00
1.7
1.7
3.19
3.26
ratio
0.13
23
221
14
135
1.04
0.00
3.2
20.4
75.88
70.45
%
0.47
14
135
12
125
0.96
0.00
2.0
1.9
4.81
3.79
mg/l
—
7
83
32
324
0.99
0.00
1.2
1.3
2.22
2.31
u/ml
0.03
24
249
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
6
65
0.92
-0.00
1.2
1.4
32.28
22.05
u/l
—
6
56
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
5
49
1.02
-0.00
4.0
3.4
—
—
—
0
0
6
67
0.89
-0.00
3.7
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.5
—
—
—
0
0
6
66
0.91
-0.00
1.7
1.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.3
—
79.88
—
0
8
9
89
1.01
-0.00
2.0
2.6
7.72
8.22
ug/l
—
9
78
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
49
1.02
-0.00
4.0
3.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
437.40
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint P16_OTH_DISORD_ORIGINA_PERINA_PERIOD and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| P16_OTH_DISORD_ORIGINA_PERINA_PERIOD | 3.808 [2.79, 5.19] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.641 |
During the follow-up period (1.1.1998 — 31.12.2019), 143 out of 8343 females with P16_OTH_DISORD_ORIGINA_PERINA_PERIOD died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| P16_OTH_DISORD_ORIGINA_PERINA_PERIOD | 3.23 [2.24, 4.66] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 145 out of 9291 males with P16_OTH_DISORD_ORIGINA_PERINA_PERIOD died.
Mortality risk
Mortality risk for people of age
years, who have P16_OTH_DISORD_ORIGINA_PERINA_PERIOD.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.346% | 0.536% |
| 5 | 2.175% | 3.4% |
| 10 | 5.482% | 9.188% |
| 15 | 10.433% | 16.711% |
| 20 | 18.473% | 26.947% |
Relationships between endpoints
↥Index endpoint: P16_OTH_DISORD_ORIGINA_PERINA_PERIOD – Other disorders originating in the perinatal period
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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