Fetal death of unspecified cause

P16_FETAL_DEATH_UNSP_CAUSE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 P95
  • Cause of death: ICD-10 P95

2 out of 7 registries used, show all original rules.

66

4. Check minimum number of events

None

66

5. Include endpoints

None

66

6. Filter based on genotype QC (FinnGen only)

60

Control definitions (FinnGen only)

Control exclude
P16_OTH_DISORD_ORIGINA_PERINA_PERIOD

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P9
Name in latin
Mors fetus causa non specificata

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 391 384 -
Only index persons 380 378 -
Unadjusted period prevalence (%)
Whole population 0.01 0.01 -
Only index persons 0.01 0.01 -
Median age at first event (years)
Whole population 31.05 31.27 -
Only index persons 31.20 31.27 -

-FinnGen-

Key figures

All Female Male
Number of individuals 60 60 -
Unadjusted period prevalence (%) 0.02 0.02 -
Median age at first event (years) 31.78 31.78 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
60
Matched controls
600
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
P95
ICD-10 Finland
Fetal death of unspecified cause
+∞
86.1
60
*
G02CB01
ATC
bromocriptine; systemic
31.8
19.0
25
13
O36.4
ICD-10 Finland
Maternal care for intrauterine death
77.3
15.7
17
*
Z39.2
ICD-10 Finland
Routine postpartum follow-up
7.8
14.5
31
72
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
6.6
11.8
28
70
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
17.7
11.0
17
13
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
11.7
8.7
16
18

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
6
16
4.04
1.99
2.7
3.8
—
—
—
0
0
15
75
2.33
1.90
2.9
2.7
8.13
132.56
ng/l
—
8
32
5
12
4.44
1.86
2.0
1.2
—
—
—
0
0
20
122
1.96
1.52
4.1
2.5
—
—
—
0
0
9
42
2.34
1.41
1.0
1.2
—
—
—
0
0
0
37
0.00
1.40
0.0
1.1
—
1.67
—
0
37
0
37
0.00
1.40
0.0
1.1
—
0.88
—
0
37
8
151
0.46
1.39
3.0
1.7
—
—
—
0
0
11
58
2.10
1.21
3.5
2.1
—
—
—
0
0
40
319
1.76
1.21
4.4
3.6
—
17.40
—
0
5
6
28
2.27
0.94
20.8
5.2
1.27
1.67
mmol/l
—
6
28
12
72
1.83
0.93
6.3
3.8
3.88
4.24
e9/l
0.18
12
65
10
158
0.56
0.86
9.2
5.4
—
—
—
0
0
35
285
1.55
0.85
3.4
3.1
0.00
0.00
estimate
—
6
56
9
142
0.57
0.83
3.0
1.8
115.33
126.43
u/l
—
9
136
8
48
1.77
0.82
3.4
4.3
4.38
4.88
pmol/l
—
8
41
42
358
1.58
0.81
4.5
3.7
—
—
—
0
0
35
288
1.52
0.78
3.5
3.1
0.00
0.00
estimate
—
6
55
5
23
2.28
0.78
3.8
3.2
71.30
68.22
g/l
—
5
23
19
137
1.57
0.77
3.3
1.2
2.26
2.13
g/l
0.08
13
95
25
193
1.51
0.75
5.6
4.4
37.90
37.24
g/l
0.32
25
188
19
138
1.55
0.75
2.1
2.1
—
—
—
0
0
5
26
2.00
0.72
29.4
6.0
—
—
—
0
0
10
62
1.74
0.70
1.2
1.4
—
—
—
0
0
16
114
1.55
0.68
2.5
3.3
—
—
—
0
0
53
488
1.74
0.66
18.5
14.5
331.34
331.68
g/l
0.09
53
488
19
243
0.68
0.63
2.6
2.0
—
—
—
0
0
8
52
1.62
0.62
1.4
1.6
1672.00
1068.20
nmol/l
—
8
41
5
88
0.53
0.62
4.8
2.1
2.49
2.41
mmol/l
—
5
80
6
36
1.74
0.59
2.5
5.5
7.37
7.37
ph
—
6
23
17
127
1.47
0.58
1.9
1.8
—
—
—
0
0
13
92
1.53
0.56
7.3
3.6
—
—
—
0
0
18
228
0.70
0.55
31.7
9.4
0.01
0.00
e9/l
0.65
18
184
6
39
1.60
0.55
22.2
5.6
104.33
105.03
mmol/l
—
6
39
33
285
1.35
0.48
3.6
3.1
0.00
0.00
estimate
—
5
57
12
88
1.45
0.44
1.5
1.4
—
—
—
0
0
8
58
1.44
0.44
1.1
1.0
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
15
117
1.38
0.40
2.1
2.3
—
—
—
0
0
5
75
0.64
0.38
1.6
1.2
—
—
—
0
0
11
82
1.42
0.37
1.8
1.9
—
—
—
0
0
6
45
1.37
0.35
1.0
1.1
—
—
—
0
0
27
235
1.27
0.34
2.9
2.8
6.20
6.10
ph
0.20
20
148
17
201
0.78
0.30
2.6
1.8
98.00
98.85
pmol/l
0.04
12
120
19
162
1.25
0.27
14.5
6.4
—
—
—
0
0
18
153
1.25
0.26
17.4
6.5
—
—
—
0
0
13
156
0.79
0.25
1.6
1.3
51.54
26.57
iu/ml
—
7
57
18
154
1.24
0.25
2.9
3.0
0.00
0.00
estimate
—
6
56
53
509
1.35
0.24
4.2
3.8
5.62
5.61
mmol/l
0.02
53
481
0
11
0.00
0.21
0.0
2.0
—
7.45
—
0
11
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
0
11
0.00
0.21
0.0
4.3
—
4.62
—
0
11
0
10
0.00
0.21
0.0
2.1
—
10.19
—
0
10
0
10
0.00
0.21
0.0
2.1
—
5.02
—
0
10
0
14
0.00
0.20
0.0
3.9
—
60.14
—
0
14
60
586
+∞
0.20
32.6
18.2
6.45
6.54
e9/l
0.15
60
578
60
586
+∞
0.20
32.5
18.1
4.48
4.48
e12/l
0.00
60
579
6
51
1.20
0.20
1.7
1.5
—
—
—
0
0
35
326
1.18
0.19
4.2
3.3
66.45
65.75
ug/l
0.02
35
313
7
58
1.23
0.19
5.9
2.3
2.38
2.47
g/l
—
7
53
7
60
1.19
0.18
2.6
1.5
—
—
—
0
0
7
60
1.19
0.18
2.1
2.0
—
—
—
0
0
55
534
1.36
0.18
4.5
4.2
1.51
1.57
mmol/l
0.63
55
513
11
129
0.82
0.16
2.9
1.9
3.64
2.64
mg/l
0.84
11
115
7
89
0.76
0.15
1.7
1.5
—
—
—
0
0
52
506
1.21
0.15
4.1
3.6
1.22
1.23
mmol/l
0.08
52
482
24
258
0.88
0.12
16.5
6.2
0.57
0.69
%
0.59
24
243
27
288
0.89
0.12
2.9
2.7
—
—
—
0
0
24
257
0.89
0.11
16.5
6.2
8.66
8.29
%
0.23
24
245
28
296
0.90
0.10
15.7
6.6
0.12
0.19
e9/l
3.91
28
273
16
146
1.13
0.09
1.4
1.3
5.47
6.41
u/ml
—
8
67
28
265
1.11
0.09
8.2
6.7
11.55
9.57
umol/l
0.56
28
256
55
536
1.31
0.08
26.4
11.9
17.69
16.99
mg/l
0.08
42
413
15
137
1.13
0.08
6.5
2.9
34.40
11.83
ng/l
—
5
56
6
70
0.84
0.08
9.5
2.6
0.86
0.83
mmol/l
—
6
65
6
73
0.80
0.08
3.2
2.0
—
—
—
0
0
53
519
1.18
0.07
26.4
10.4
139.85
139.88
mmol/l
0.03
53
509
53
520
1.16
0.07
27.2
10.5
3.90
3.89
mmol/l
0.08
53
508
9
84
1.08
0.07
1.3
1.6
489.44
468.37
pmol/l
—
9
78
49
479
1.13
0.06
5.6
4.6
37.59
37.12
mmol/mol
0.12
49
468
27
282
0.92
0.06
15.5
6.4
0.51
0.52
e9/l
0.10
27
254
27
282
0.92
0.06
15.2
6.4
0.04
0.04
e9/l
0.08
27
252
16
149
1.10
0.06
3.6
2.3
—
—
—
0
0
17
161
1.08
0.03
6.2
2.3
47.59
55.13
u/l
0.52
17
156
27
261
1.06
0.03
15.4
6.0
54.34
56.27
%
0.44
27
251
25
258
0.95
0.02
15.8
6.1
2.18
2.89
%
1.87
25
246
27
262
1.06
0.02
14.9
6.2
33.31
29.76
%
1.23
27
253
23
224
1.04
0.00
16.1
5.2
1.21
1.21
mmol/l
0.17
23
195
29
291
0.99
0.00
14.7
6.4
1.96
1.92
e9/l
0.13
29
269
23
227
1.02
0.00
3.8
2.7
—
—
estimate
—
0
0
45
455
0.96
0.00
5.1
5.0
13.56
14.21
pmol/l
1.12
45
442
18
182
0.98
0.00
4.2
3.3
2.38
2.34
mmol/l
0.88
18
172
11
108
1.02
0.00
5.0
2.2
—
—
estimate
—
0
0
11
112
0.98
0.00
1.2
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
6.7
—
1.31
—
0
7
0
6
0.00
-0.00
0.0
1.8
—
8.92
—
0
6
0
8
0.00
-0.00
0.0
1.5
—
90.78
—
0
8
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
7
78
0.88
-0.00
1.1
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
17.6
—
1664.29
—
0
7
52
516
1.06
-0.00
5.7
5.8
1.65
1.71
mu/l
0.18
52
500
0
6
0.00
-0.00
0.0
2.5
—
58.83
—
0
6
6
64
0.93
-0.00
1.3
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
1.54
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
6
65
0.91
-0.00
2.7
1.2
—
—
—
0
0
13
130
1.00
-0.00
5.7
2.5
7.22
8.04
mmol/l
0.25
13
113
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
13.0
—
0.68
—
0
6
0
5
0.00
-0.00
0.0
4.4
—
7.93
—
0
5
0
5
0.00
-0.00
0.0
8.2
—
3.76
—
0
5
0
7
0.00
-0.00
0.0
15.6
—
944.29
—
0
7
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
16.87
—
0
9

Mortality – FinRegistry

Association

Association between endpoint P16_FETAL_DEATH_UNSP_CAUSE and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have P16_FETAL_DEATH_UNSP_CAUSE.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: P16_FETAL_DEATH_UNSP_CAUSE – Fetal death of unspecified cause

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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