Other disturbances of cerebral status of newborn

P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — P91 Cause of death: ICD-10 — P91 2 out of 7 registries used, show all original rules.	45
4. Check minimum number of events None	45
5. Include endpoints None	45
6. Filter based on genotype QC (FinnGen only)	42

Control definitions (FinnGen only)

Control exclude: P16_OTH_DISORD_ORIGINA_PERINA_PERIOD

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: P9
Name in latin: Aliae perturbationes status cerebralis neonati

NAME	P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO
CONTROL_EXCLUDE	P16_OTH_DISORD_ORIGINA_PERINA_PERIOD
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	P91
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	P91
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Other disturbances of cerebral status of newborn based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	1980	844	1132
Only index persons	857	361	496
Unadjusted period prevalence (%)
Whole population	0.03	0.02	0.03
Only index persons	0.02	0.01	0.02
Median age at first event (years)
Whole population	0.15	0.00	0.00
Only index persons	0.01	0.01	0.01

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	42	15	27
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	0.00	0.00	0.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3009466) Valproate [Moles/volume] in Serum or Plasma

15.67

6.45

6.1

4.3

450.00

475.50

umol/l

—

(3022670) pH of Venous cord blood

7.50

2.97

1.0

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

3.13

2.65

6.3

21.9

107.15

105.52

mmol/l

0.81

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

189

2.85

2.64

7.8

7.0

177.07

175.12

u/l

0.04

175

(3020717) Zinc [Moles/volume] in Serum or Plasma

6.10

2.27

3.6

2.0

11.84

13.02

umol/l

—

(3013115) Eosinophils [#/volume] in Blood

273

2.75

2.07

6.0

13.6

0.31

0.24

e9/l

0.63

225

(3013650) Neutrophils [#/volume] in Blood by Automated count

277

2.64

1.89

7.5

13.9

2.98

3.40

e9/l

0.61

229

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

134

2.28

1.88

6.3

11.8

22.81

23.21

mmol/l

0.30

134

(3006315) Basophils [#/volume] in Blood

267

2.52

1.85

6.0

12.6

0.04

e9/l

0.02

215

(3001604) Monocytes [#/volume] in Blood

268

2.49

1.84

6.1

12.6

0.66

0.63

e9/l

0.19

216

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

3.13

1.73

9.6

37.3

0.69

0.63

—

(3019198) Lymphocytes [#/volume] in Blood

273

2.38

1.67

6.0

12.6

3.11

2.71

e9/l

0.56

229

(3014007) Fractional oxyhemoglobin in Arterial blood

3.00

1.66

9.6

36.0

96.79

96.89

—

(3000991) Gas panel - Venous blood

131

2.15

1.64

9.8

16.2

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

2.88

1.59

9.6

34.8

1.06

1.01

—

(3014218) Bicarbonate [Moles/volume] standard in Arterial blood

2.78

1.52

9.0

32.6

23.00

23.90

mmol/l

—

(3009343) pH of Capillary blood

152

2.08

1.52

27.2

11.4

7.42

7.41

0.76

118

(3023024) Carbon dioxide [Partial pressure] in Capillary blood

152

2.08

1.52

27.2

11.6

4.83

4.95

kpa

0.46

146

(40758558) Short blood count panel - Blood

190

2.09

1.50

3.5

9.3

—

(42870588) Differential panel, method unspecified - Blood

220

2.14

1.49

4.4

12.9

—

(3020630) Protein [Mass/volume] in Serum or Plasma

3.00

1.32

3.2

5.0

65.40

62.62

g/l

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

2.02

1.29

5.6

7.0

0.50

1.30

e6/l

—

(3018418) pH of Serum or Plasma

2.05

1.14

5.8

3.9

7.37

7.39

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

164

1.84

1.13

6.5

5.3

73.96

69.57

nmol/l

0.35

154

(3035637) Corticotropin [Mass/volume] in Plasma

2.33

1.11

2.4

2.2

13.47

23.18

ng/l

—

(3022313) Gas panel - Capillary blood

138

1.82

1.08

25.8

10.7

—

(3021589) Normoblasts [#/volume] in Blood

266

1.96

1.08

5.9

14.3

0.00

e9/l

-0.00

201

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

1.88

1.05

5.5

6.5

0.14

0.48

e6/l

—

(3044640) Blood type and Crossmatch panel - Blood

107

1.78

0.93

2.4

4.3

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

1.89

0.93

10.5

17.7

0.77

0.79

mmol/l

0.45

(3023520) Reticulocytes [#/volume] in Blood

1.98

0.93

2.9

6.5

68.24

65.05

e9/l

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

145

1.70

0.88

8.9

7.2

—

(3005719) IgG [Mass/volume] in Serum or Plasma

1.90

0.84

1.5

5.5

9.04

7.96

g/l

—

(3028626) Oxygen [Partial pressure] in Capillary blood

147

1.66

0.82

29.6

10.8

9.36

9.83

kpa

1.03

141

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

0.81

0.0

1.3

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

2.32

0.79

1.4

2.2

—

(3002582) Erythrocytes [#/volume] in Urine

139

1.65

0.79

9.0

7.2

6.05

483.39

e6/l

0.53

108

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

362

0.57

0.75

4.3

4.2

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

201

0.62

0.73

1.9

2.1

—

(3016879) Cocaine [Presence] in Urine

1.96

0.71

1.2

1.9

—

(3027944) Amphetamines [Presence] in Urine

1.96

0.71

1.2

1.9

—

(3000764) Benzodiazepines [Presence] in Urine

1.96

0.71

1.2

1.9

—

(3027008) Opiates [Presence] in Urine

1.96

0.71

1.2

1.9

—

(3015736) pH of Urine

152

1.58

0.70

7.7

4.3

6.08

6.39

—

(3028300) Cannabinoids [Presence] in Urine

1.88

0.68

1.2

1.9

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

1.88

0.68

1.8

22.6

138.20

122.57

g/l

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

1.75

0.63

2.2

1.3

—

(3021387) Prolactin [Units/volume] in Serum or Plasma

0.00

0.62

0.0

1.7

—

434.59

—

(3011648) Oxygen content in Venous blood

0.00

0.61

0.0

23.0

—

12.36

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

228

1.48

0.53

11.6

13.9

5.99

5.84

mmol/l

0.10

217

(3030467) Casts [#/volume] in Urine by Automated count

131

1.49

0.53

6.6

7.0

0.00

0.50

e6/l

1.27

102

(3026008) Bacteria identified in Urine by Culture

1.61

0.52

4.8

3.5

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

161

1.44

0.50

31.7

17.7

24.45

24.42

mmol/l

0.02

161

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.47

0.48

5.6

2.4

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.47

0.48

5.4

2.3

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

1.46

0.44

4.7

3.1

2.45

2.44

mmol/l

0.18

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

1.41

0.43

3.6

5.4

60.25

55.17

u/l

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.42

0.0

1.7

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

0.42

0.0

1.3

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

1.43

0.42

5.2

2.7

739.56

688.33

u/l

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

0.00

0.41

0.0

1.1

—

3.17

—

(3023511) Choriogonadotropin [Units/volume] in Urine

0.00

0.41

0.0

1.3

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.41

0.0

1.6

—

(3014133) Dog dander IgE Ab [Units/volume] in Serum

1.44

0.39

1.2

20.54

10.74

u/ml

—

(3023368) Bacteria identified in Blood by Culture

1.48

0.38

5.6

4.6

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

187

1.35

0.37

4.9

31.27

57.53

ug/l

2.23

176

(3014326) Insulin-like growth factor-I [Moles/volume] in Serum or Plasma

1.42

0.36

6.7

4.6

18.50

21.16

nmol/l

—

(3013707) Erythrocyte sedimentation rate [Velocity] in Red Blood Cells by Westergren method

222

1.29

0.29

7.2

5.9

7.56

9.35

mm/h

0.44

210

(3018095) Leukocytes [#/volume] in Urine

164

1.28

0.26

13.6

8.8

25.90

23.26

e6/l

0.06

109

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

1.33

0.26

2.8

4.1

—

(36660697) Celiac disease serology panel - Serum

0.72

0.25

1.3

1.4

—

(40761511) CBC panel - Blood by Automated count

347

1.42

0.25

15.2

9.6

—

(3018677) aPTT in Platelet poor plasma by Coagulation assay

1.34

0.25

2.5

8.0

33.70

31.51

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

328

1.33

0.23

33.7

20.5

139.20

139.06

mmol/l

0.14

323

(3023103) Potassium [Moles/volume] in Serum or Plasma

329

1.31

0.23

33.1

20.4

4.02

4.06

mmol/l

0.25

319

(3000494) Fungus identified in Specimen by Culture

1.21

0.22

1.8

1.6

—

(3038071) Oxygen [Partial pressure] in Mixed venous blood

0.00

0.21

0.0

2.7

—

4.82

—

(3021513) Carbon dioxide [Partial pressure] in Mixed venous blood

0.00

0.21

0.0

2.7

—

6.12

—

(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells

0.00

0.21

0.0

3.2

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.21

0.0

2.2

—

(3007302) Hemoglobin [Mass/volume] in Mixed venous blood

0.00

0.21

0.0

2.7

—

93.90

—

(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells

0.00

0.21

0.0

3.2

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.21

0.0

7.9

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.6

—

46.83

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

0.21

0.0

1.2

—

(3028026) IgM [Mass/volume] in Serum or Plasma

1.29

0.21

1.3

3.0

0.88

1.13

g/l

—

(3005715) Vancomycin [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

6.3

—

9.88

—

(3016018) Differential panel - Cerebral spinal fluid

0.00

0.20

0.0

6.5

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.25

0.19

5.6

2.4

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

1.18

0.18

2.1

9.6

68.29

84.90

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

121

1.23

0.18

3.2

4.5

2.73

2.30

mg/l

0.34

109

(3007853) Bacteria identified in Skin by Aerobe culture

0.77

0.17

2.0

1.9

—

(40764999) Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)/1.73 sq M

132

1.21

0.16

14.4

7.0

117.33

106.61

ml/min/173m2

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

123

1.20

0.15

3.3

4.5

—

estimate

—

(3010726) Horse dander IgE Ab [Units/volume] in Serum

1.06

0.09

1.3

1.14

0.71

u/ml

—

(3023351) European house dust mite IgE Ab [Units/volume] in Serum

0.78

0.09

1.6

1.3

0.18

1.88

u/ml

—

(40760892) CBC W Ordered Manual Differential panel - Blood

0.85

0.08

10.7

5.6

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

371

1.18

0.08

26.0

14.5

21.48

24.96

mg/l

0.38

259

(3019150) Specific gravity of Urine by Refractometry

1.10

0.08

10.1

3.6

1.02

kg/l

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

149

1.12

0.06

1.8

2.4

—

(3003694) ABO and Rh group [Type] in Blood

120

1.12

0.05

1.2

1.9

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

189

0.92

0.04

1.7

2.2

5.92

7.13

u/ml

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

327

0.92

0.02

16.0

11.8

28.88

26.18

u/l

0.29

319

(3020564) Creatinine [Moles/volume] in Serum or Plasma

337

1.04

0.00

18.5

13.7

46.50

49.47

umol/l

0.30

331

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

183

0.97

0.00

4.2

36.87

35.86

mmol/mol

0.15

171

(3044889) 12 lead EKG panel

124

0.96

0.00

1.5

2.5

—

(3007164) IgA [Mass/volume] in Serum or Plasma

195

1.05

0.00

1.4

2.2

1.86

1.34

g/l

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

292

0.98

0.00

4.1

4.2

1.93

2.21

mu/l

0.82

278

(4024509) Urine culture

0.00

0.0

2.7

—

(3024471) HLA-A [Type]

0.00

0.0

1.0

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.0

1.1

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

0.0

1.3

—

(3042936) Bacteria identified in Isolate by Culture

0.94

0.00

2.6

2.0

—

(3024932) HLA-DR beta [Type]

0.00

0.0

1.1

—

(3041082) Glomerular basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.0

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

-0.00

0.0

1.0

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

-0.00

0.0

1.4

—

(42870560) Thyrotropin [Units/volume] in Cord blood

1.03

-0.00

1.0

16.10

8.72

mu/l

—

(1175556) inFLIXimab Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

10.8

—

(44813793) Dust mix specific IgE antibody measurement

0.00

-0.00

0.0

1.0

—

(3032700) Glomerular basement membrane Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3032352) Blasts [#/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

13.4

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

3.6

—

22.23

—

(3001186) Copper [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

28.22

—

(3036035) von Willebrand factor (vWf) Ag actual/normal in Platelet poor plasma by Immunoassay

0.00

-0.00

0.0

1.0

—

128.60

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.4

—

(3035999) Lactate [Moles/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

2.2

—

1.35

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

-0.00

0.0

1.0

—

(3013247) Albumin in CSF/Albumin in Serum or Plasma

0.00

-0.00

0.0

1.0

—

2.56

—

(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay

0.00

-0.00

0.0

1.4

—

(3018921) Toxoplasma gondii IgA Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.4

—

(3029715) Chromosome analysis.interphase [Interpretation] in Bone marrow by FISH Narrative

0.00

-0.00

0.0

1.6

—

(3008401) Mugwort IgE Ab [Units/volume] in Serum

0.84

-0.00

1.6

1.3

0.24

1.61

u/ml

—

(21494429) FMR1 gene CGG repeat analysis in Blood or Tissue by Molecular genetics method

0.00

-0.00

0.0

1.0

—

(3011985) Renin [Units/volume] in Plasma

0.00

-0.00

0.0

1.8

—

39.50

—

(3045142) Bone marrow Pathology biopsy report

0.00

-0.00

0.0

2.3

—

(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay

0.00

-0.00

0.0

1.4

—

(3008092) Baker's yeast IgG Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

-0.00

0.0

1.0

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3006598) pH of Arterial cord blood

1.00

-0.00

1.0

—

(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid

0.00

-0.00

0.0

1.6

—

(4268621) Lupus anticoagulant assay

0.00

-0.00

0.0

2.4

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

1.64

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

4.2

—

0.78

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.2

—

(3042299) inFLIXimab [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

18.4

—

9.04

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

3.3

—

(3007798) IgG/Albumin [Mass Ratio] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

-0.00

0.0

1.2

—

(3001788) Aldosterone [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.8

—

150.00

—

(3022411) Androstenedione [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

3.0

—

2.40

—

(3016031) Almond IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.3

—

2.62

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

0.86

—

(3017115) Methotrexate [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

37.6

—

0.66

—

(3024474) Albumin [Mass/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

95.50

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

0.00

-0.00

0.0

3.0

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

0.86

-0.00

3.2

11.3

137.40

1292.93

ng/l

—

(3041672) Baker's yeast Ab [Presence] in Serum

0.00

-0.00

0.0

1.2

—

(40760109) Toxoplasma gondii IgG Ab avidity [Ratio] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.2

—

(3045683) HLA typing for celiac disease panel - Blood or Tissue

0.00

-0.00

0.0

1.0

—

(3028433) Virus identified in Specimen by Culture

0.00

-0.00

0.0

1.5

—

(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.8

—

1096.80

—

(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid

0.00

-0.00

0.0

1.2

—

(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3040893) Potassium [Moles/volume] in Capillary blood

0.00

-0.00

0.0

2.2

—

4.07

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

7.9

—

42.87

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(21494755) Public health laboratory ask at order entry panel

0.00

-0.00

0.0

1.3

—

(3008733) Herpes simplex virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

-0.00

0.0

2.6

—

Mortality – FinRegistry

↥

Association

Association between endpoint P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO and mortality.

Females

Parameter	HR [95% CI]	p-value
P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO	8.612 [3.55, 20.9]	< 0.001
Birth year	0.991 [0.98, 1.0]	0.042

During the follow-up period (1.1.1998 — 31.12.2019), 54 out of 695 females with P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO died.

Males

Parameter	HR [95% CI]	p-value
P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO	11.971 [4.15, 34.5]	< 0.001
Birth year	0.989 [0.98, 1.0]	0.022

During the follow-up period (1.1.1998 — 31.12.2019), 64 out of 949 males with P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO died.

Mortality risk

Mortality risk for people of age

years, who have P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO.

N-year risk	Females	Males
1	0.702%	2.331%
5	4.077%	12.945%
10	9.595%	29.693%
15	18.288%	51.317%
20	29.999%	72.107%

Relationships between endpoints

↥

Index endpoint: P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO – Other disturbances of cerebral status of newborn

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Other disturbances of cerebral status of newborn

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints