Neuroendocrine tumor and carcinoma of lung

C3_LUNG_NEUROENDO

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cancer registry: Topography ICD-O-3 C34
  • Cancer registry: Morphology ICD-O-3 8240|8246|8249
  • Cancer registry: Behaviour codes 3

1 out of 7 registries used, show all original rules.

337

4. Check minimum number of events

None

337

5. Include endpoints

None

337

6. Filter based on genotype QC (FinnGen only)

304

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF9

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 304 196 108
Unadjusted period prevalence (%) 0.06 0.07 0.05
Median age at first event (years) 65.25 64.90 65.87

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
313
Matched controls
3130
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
263.9
307.7
164
13
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
30.1
214.0
187
147
UGC12
NOMESCO Finland
Flexible bronchoscopy
21.5
145.9
130
100
H02AB02
ATC
dexamethasone; systemic
50.3
103.0
61
15
GDC01
NOMESCO Finland
Thoracoscopic lobectomy of lung
+∞
95.9
87
*
C34.37
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung carcinoid
+∞
93.5
85
*
130
Kela drug reimbursment
Malignant tumour
+∞
92.4
84
*
C34.17
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary carcinoid
+∞
91.2
83
*
8240/3-C34.9
ICD-O-3
Neuroendocrine tumor, NOS, of lung, NOS
+∞
75.1
69
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
21.8
67.9
53
29
8240/3-C34.3
ICD-O-3
Neuroendocrine tumor, NOS, of lower lobe, lung
+∞
66.0
61
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
11.9
59.7
67
70
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
6.7
58.3
129
296
JN4BD
NOMESCO Finland
Extensive body CT
13.0
57.5
60
56
GD1AD
NOMESCO Finland
Thorax CT examination
11.0
55.8
66
74
A04AA01
ATC
ondansetron; systemic, rectal
15.1
52.3
49
38
WZC30
NOMESCO Finland
Teaching
6.6
51.5
106
224
GDC00
NOMESCO Finland
Lobectomy of lung
+∞
49.3
46
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
6.5
48.4
243
1093
8240/3-C34.1
ICD-O-3
Neuroendocrine tumor, NOS, of upper lobe, lung
+∞
47.1
44
*
C34.27
ICD-10 Finland
Malignant tumor of the middle lobe, bronchus or lung carcinoid
+∞
47.1
44
*
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
94.3
44.3
48
6
JN4AD
NOMESCO Finland
Body CT examination
8.3
41.5
61
89
ZXE20
NOMESCO Finland
More than three and less than five hours
5.5
36.2
86
202
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
36.1
34
*
A03FA01
ATC
metoclopramide; systemic, rectal
4.9
34.7
98
266
Z51.5
ICD-10 Finland
Palliative care
9.3
34.2
44
54
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
8.2
33.2
48
68
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
32.9
31
*
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
98.2
32.5
35
*
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
+∞
31.8
30
*
A04AA02
ATC
granisetron; systemic, transdermal
+∞
31.8
30
*
GDB21
NOMESCO Finland
Thoracoscopic segmental resection of lung
+∞
31.8
30
*
8246/3-C34.9
ICD-O-3
Neuroendocrine carcinoma, NOS, of lung, NOS
+∞
31.8
30
*
R4110
NOMESCO Finland
Physiotherapy
4.0
31.0
139
526
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
30.7
29
*
8240/3-C34.2
ICD-O-3
Neuroendocrine tumor, NOS, of middle lobe, lung
+∞
29.7
28
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
320.2
29.3
29
*
WX402
NOMESCO Finland
General anaesthesia
4.1
28.4
104
339
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
11.0
27.8
31
31
XX3DW
NOMESCO Finland
Time consuming IT work
7.4
27.6
43
66
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
106.2
27.1
29
*
115
Kela drug reimbursment
Breast cancer
+∞
26.4
25
*
B01AB04
ATC
dalteparin; parenteral
8.2
25.6
36
49
C34.97
ICD-10 Finland
Malignant tumor in unspecified location in bronchial and pulmonary carcinoid
+∞
25.4
24
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
25.4
24
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
24.3
23
*
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
29.5
24.1
32
12
TPH07
NOMESCO Finland
Cathetrisation of artery
4.6
23.9
66
172
H01CB03
ATC
lanreotide; parenteral
+∞
23.2
22
*
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
6.5
22.9
40
69
B01AB05
ATC
enoxaparin; parenteral
3.2
22.4
143
650
L01BC06
ATC
capecitabine; oral
+∞
22.1
21
*
C34.90
ICD-10 Finland
Malignant tumor in unspecified location in bronchus and lung without histology
+∞
22.1
21
*
L01CB01
ATC
etoposide; systemic
+∞
22.1
21
*
WX408
NOMESCO Finland
General anesthesy, balanced
3.4
22.0
107
413
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
6.3
20.8
37
65
WF002
NOMESCO Finland
Radical radiotherapy
78.4
20.0
22
*
R84
ICPC
Malignant neoplasm bronchus/lung
212.9
19.8
20
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.2
19.8
61
172
JN4CD
NOMESCO Finland
Very extensive body CT
21.8
19.4
28
14
N03AX16
ATC
[U] pregabalin
3.1
19.2
116
503
XGX32
NOMESCO Finland
Bronchoscopic ultrasonography
74.6
18.9
21
*
GDB11
NOMESCO Finland
Thoracoscopic wedge resection of lung
74.6
18.9
21
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
18.9
18
*
8246/3-C34.1
ICD-O-3
Neuroendocrine carcinoma, NOS, of upper lobe, lung
+∞
18.9
18
*
L03AA13
ATC
pegfilgrastim; parenteral
106.5
18.8
20
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.4
18.5
84
307
C34.30
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung without histology
+∞
17.9
17
*
L01AX03
ATC
temozolomide; systemic
+∞
17.9
17
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.8
17.7
144
728
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
6.0
17.3
32
58
C61
ICD-10 Finland
Malignant neoplasm of prostate
+∞
16.8
16
*
L02BG04
ATC
letrozole; oral
50.3
16.2
19
*
N02AX02
ATC
tramadol; systemic, rectal
2.6
15.9
176
1022
C34.19
ICD-10 Finland
Malignant tumor of the upper lobe, bronchus or lung other or unspecified histology
+∞
15.8
15
*
C34.87
ICD-10 Finland
Malignant overall tumor of bronchial and pulmonary carcinoid
+∞
15.8
15
*
JN5ER
NOMESCO Finland
PET-CT of receptors in whole body
+∞
15.8
15
*
C34.9
ICD-10 Finland
Malignant neoplasm: Bronchus or lung, unspecified
+∞
15.8
15
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
15.8
15
*
8249/3-C34.3
ICD-O-3
Neuroendocrine tumor, grade 2 of lower lobe, lung
+∞
15.8
15
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.6
15.1
145
782
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
6.4
15.0
26
44
N02AA05
ATC
oxycodone; systemic
3.2
15.0
72
269
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
14.7
14
*
8249/3-C34.1
ICD-O-3
Neuroendocrine tumor, grade 2 of upper lobe, lung
+∞
14.7
14
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
14.7
14
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
14.7
14
*
HAB40
NOMESCO Finland
Wedge excision of mammary gland
38.0
14.6
18
5
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
6.8
14.3
23
36
TGD00
NOMESCO Finland
Needle biopsy of lung
78.7
13.7
15
*
D05.1
ICD-10 Finland
Intraductal carcinoma in situ
+∞
13.6
13
*
C34.07
ICD-10 Finland
Malignant tumor of the main bronchus carcinoid
+∞
13.6
13
*
C34.39
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung other or unspecified histology
+∞
13.6
13
*
C34.10
ICD-10 Finland
Malignant tumor of the upper lobe, bronchus or lung without histology
+∞
13.6
13
*
C34.99
ICD-10 Finland
Malignant tumor in unspecified localization in bronchial and pulmonary other or unspecified histology
+∞
13.6
13
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
13.6
13
*
R04.2
ICD-10 Finland
Haemoptysis
6.0
13.6
25
45
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
42.0
13.3
16
*
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
4.6
12.8
32
76
ZX090
NOMESCO Finland
Other technic of radiotherapy
72.9
12.7
14
*
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
6.0
12.6
23
41
JN7AQ
NOMESCO Finland
Somatostatin receptor SPET med low dose CT
+∞
12.6
12
*
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
+∞
12.6
12
*
C34.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bronchus and lung
+∞
12.6
12
*
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
+∞
12.6
12
*
L02BA01
ATC
tamoxifen; oral
135.2
12.5
13
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
135.2
12.5
13
*
R03BB04
ATC
tiotropium bromide; inhalant
3.2
12.3
55
196
WZC00
NOMESCO Finland
Treatment plan or consultation
2.4
12.1
112
581
ZXE00
NOMESCO Finland
One hour or less
2.3
11.9
138
791
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
11.5
11
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
11.5
11
*
C34.3
ICD-10 Finland
Malignant neoplasm: Lower lobe, bronchus or lung
+∞
11.5
11
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
11.5
11
*
E34.0
ICD-10 Finland
Carcinoid syndrome
+∞
11.5
11
*
D14.3
ICD-10 Finland
Benign neoplasm: Bronchus and lung
124.4
11.5
12
*
Z2221
NOMESCO Finland
Medical doctor
2.5
11.5
99
496
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.3
10.7
106
563
ZXE30
NOMESCO Finland
More than five and less than seven hours
5.7
10.5
20
37
HAC20
NOMESCO Finland
Total mastectomy
+∞
10.5
10
*
C34.20
ICD-10 Finland
Malignant tumor of the middle lobe, bronchus or lung without histology
+∞
10.5
10
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
10.5
10
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
10.5
10
*
C34.00
ICD-10 Finland
Malignant tumor of the main bronchus without histology
+∞
10.5
10
*
A79
ICPC
Malignancy NOS
+∞
10.5
10
*
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
3.0
10.4
50
185
ZXA00
NOMESCO Finland
Right side
2.3
9.8
103
557
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
56.8
9.7
11
*
H01CB02
ATC
octreotide; parenteral
103.0
9.5
10
*
C34.15
ICD-10 Finland
Malignant tumor of the anterior, bronchial or lung other non-microcellular carcinoma
+∞
9.4
9
*
C34.32
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung adenocarcinoma
+∞
9.4
9
*
C34.12
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary adenocarcinoma
+∞
9.4
9
*
HAE10
NOMESCO Finland
Reconstruction of breast using graft or flap
+∞
9.4
9
*
HA1AA
NOMESCO Finland
X-ray mammography
4.2
9.2
25
63
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
12.0
9.2
16
14
UGC18
NOMESCO Finland
Flexible bronchoscopy with biopsy of lung
37.9
9.1
11
*
R03AK08
ATC
formoterol and beclometasone; inhalant
3.9
8.9
27
74
WX892
NOMESCO Finland
Monitored bed care
3.3
8.9
35
115
R03AC02
ATC
salbutamol; inhalant
2.1
8.8
197
1405
XG410
NOMESCO Finland
Flow-volume spirometry
4.2
8.8
24
61
WX600
NOMESCO Finland
Single shot through catheter
28.4
8.5
11
*
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
4.9
8.5
19
41
GD5CD
NOMESCO Finland
Thorax and upper abdomen combined very extensive CT examination of
92.4
8.5
9
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
92.4
8.5
9
*
WX250
NOMESCO Finland
Intercostal blockade
92.4
8.5
9
*
Z3226
NOMESCO Finland
Physiotherapist
2.4
8.4
70
340
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.0
8.4
24
63
A04AD12
ATC
aprepitant; systemic
+∞
8.4
8
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
8.4
8
*
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
+∞
8.4
8
*
8246/3-C34.3
ICD-O-3
Neuroendocrine carcinoma, NOS, of lower lobe, lung
+∞
8.4
8
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
+∞
8.4
8
*
L03AA02
ATC
filgrastim; parenteral
+∞
8.4
8
*
GD1AT
NOMESCO Finland
Biopsy of the lung with ultrasound guidance
+∞
8.4
8
*
GDC20
NOMESCO Finland
Lobectomy of lung and sleeve resection of bronchus
+∞
8.4
8
*
XX2RW, ,
NOMESCO Finland
22.7
8.1
11
5
A02BC02
ATC
pantoprazole; systemic
2.1
8.0
231
1781
ZXC96
NOMESCO Finland
Robot assisted procedure
18.9
7.7
11
6
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.3
7.5
29
94
J01MA14
ATC
moxifloxacin; systemic
2.9
7.5
37
139
XX9AN
NOMESCO Finland
Complementary isotope examination or additional picture
82.0
7.4
8
*
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
+∞
7.3
7
*
XX7JT
NOMESCO Finland
Somatostatin isotope ablative therapy
+∞
7.3
7
*
GCA05
NOMESCO Finland
Bronchoscopic laser therapy of lesion of bronchus
+∞
7.3
7
*
8240/3-C34.0
ICD-O-3
Neuroendocrine tumor, NOS, of main bronchus
+∞
7.3
7
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
7.3
7
*
WZC15, ,
NOMESCO Finland
+∞
7.3
7
*
C34.16
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary microcellular carcinoma
+∞
7.3
7
*
C50
ICD-10 Finland
Malignant neoplasm of breast
+∞
7.3
7
*
8500/2-C50.9
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of breast, NOS
+∞
7.3
7
*
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
+∞
7.3
7
*
PJD99
NOMESCO Finland
Excision of other lymph nodes
+∞
7.3
7
*
8249/3-C34.2
ICD-O-3
Neuroendocrine tumor, grade 2 of middle lobe, lung
+∞
7.3
7
*
C50.91
ICD-10 Finland
Malignant tumor in another specified localization in ductal mammary gland
+∞
7.3
7
*
C77.1
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intrathoracic lymph nodes
+∞
7.3
7
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
+∞
7.3
7
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
7.3
7
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.8
7.3
38
147
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.6
7.2
46
197
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
8.2
7.2
15
19
Z3231
NOMESCO Finland
Registered nurse
2.0
7.0
89
509
H02AB06
ATC
prednisolone; systemic
1.9
7.0
161
1127
JN3AD
NOMESCO Finland
Abdominal CT examination
2.5
7.0
47
207
R52.0
ICD-10 Finland
Acute pain
4.1
6.8
19
49
GDA20
NOMESCO Finland
Excision of lesion of lung
41.0
6.8
8
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
6.8
74
400
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.9
6.8
33
123
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
7.7
6.5
14
19
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
71.2
6.4
7
*
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
14.7
6.4
10
7
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
7.3
6.3
14
20
WX110
NOMESCO Finland
Infiltration anesthesia
1.9
6.3
217
1702
8249/3-C34.9
ICD-O-3
Neuroendocrine tumor, grade 2 of lung, NOS
+∞
6.3
6
*
D44.8
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pluriglandular involvement
+∞
6.3
6
*
HAE20
NOMESCO Finland
Reconstruction of areola and mamilla using graft or flap
+∞
6.3
6
*
116
Kela drug reimbursment
Prostate cancer
+∞
6.3
6
*
GDC10
NOMESCO Finland
Bilobectomy of lung
+∞
6.3
6
*
C34.2
ICD-10 Finland
Malignant neoplasm: Middle lobe, bronchus or lung
+∞
6.3
6
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
6.3
6
*
GDB20
NOMESCO Finland
Segmental resection of lung
+∞
6.3
6
*
J93.8
ICD-10 Finland
Other pneumothorax
+∞
6.3
6
*
C50.11
ICD-10 Finland
Malignant tumor of the central part of the mammary gland,ductal tumor
+∞
6.3
6
*
Z85.3
ICD-10 Finland
Personal history of malignant neoplasm of breast
+∞
6.3
6
*
J01FA06
ATC
roxithromycin; oral
1.8
6.3
141
970
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.2
6.1
54
268
J01MA12
ATC
levofloxacin; systemic
2.1
6.1
62
326

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
123
77
25.67
153.30
1.5
1.3
—
—
—
0
0
108
200
7.72
60.53
1.6
1.1
—
—
—
0
0
87
139
8.28
55.42
2.7
1.6
21.84
2.58
ug/l
0.52
70
108
194
855
4.34
35.90
3.1
1.7
—
—
—
0
0
243
1411
4.23
27.09
11.5
6.5
4.24
4.19
e9/l
0.13
214
1224
231
1305
3.94
26.64
10.0
14.1
1.11
1.26
inr
4.84
177
1086
164
750
3.49
26.44
3.0
2.0
—
—
—
0
0
175
854
3.38
24.99
6.9
5.7
—
—
—
0
0
94
320
3.77
23.62
8.5
7.9
7.40
7.42
ph
0.83
38
193
135
579
3.34
23.59
2.8
1.9
—
—
—
0
0
212
1208
3.34
22.49
7.2
6.0
0.72
0.70
%
0.17
206
1116
212
1208
3.34
22.49
7.2
5.8
2.66
2.99
%
1.76
206
1119
212
1209
3.34
22.43
7.3
6.0
8.88
8.73
%
0.37
206
1122
213
1227
3.30
21.97
7.3
5.8
26.62
27.89
%
0.97
207
1156
203
1140
3.22
21.83
5.3
3.9
35.50
36.00
g/l
0.62
197
1056
224
1351
3.31
20.92
7.0
5.8
1.80
1.86
e9/l
0.45
194
1176
221
1326
3.27
20.75
7.0
5.7
0.60
0.57
e9/l
0.96
188
1129
222
1337
3.27
20.68
7.0
5.7
0.04
0.04
e9/l
0.34
189
1142
100
384
3.36
20.54
1.9
1.8
30.00
29.50
s
0.40
100
371
69
209
3.95
20.29
10.8
7.6
—
—
—
0
0
208
1223
3.09
19.90
7.1
5.7
58.79
57.34
%
1.00
203
1155
223
1379
3.15
19.19
7.2
5.9
0.19
0.20
e9/l
0.34
193
1186
196
1139
2.93
18.73
3.0
2.4
—
—
estimate
—
0
0
155
824
2.75
17.13
5.0
3.3
7.40
7.40
ph
0.03
125
584
70
244
3.41
16.47
1.5
1.5
—
—
—
0
0
202
1248
2.74
16.23
8.8
5.7
1.22
1.21
mmol/l
0.38
197
1130
238
1601
3.03
16.19
7.2
4.8
6.91
6.72
mmol/l
0.77
230
1512
190
1158
2.63
15.37
13.9
10.3
0.00
0.00
e9/l
0.59
147
947
214
1392
2.70
14.98
9.7
6.3
1.21
1.21
mmol/l
0.26
192
1206
26
25
11.23
14.02
2.0
3.1
—
—
—
0
0
271
2039
3.45
13.64
14.6
5.7
85.71
76.63
u/l
2.53
266
1892
156
911
2.42
13.19
5.6
2.1
2.39
2.36
mmol/l
2.19
151
781
124
676
2.38
11.99
4.9
3.8
—
—
—
0
0
130
766
2.19
10.07
7.0
4.5
—
—
—
0
0
19
23
8.72
9.21
2.9
1.9
81.12
25.90
ng/l
0.64
19
23
14
9
16.20
9.12
1.0
1.0
—
—
—
0
0
53
229
2.58
8.20
4.2
7.0
8.92
10.79
mmol/l
1.33
53
216
97
551
2.10
7.92
3.9
2.0
2.49
2.45
mmol/l
3.37
91
480
111
667
2.03
7.76
3.7
2.9
—
0.00
estimate
—
0
8
116
720
1.97
7.33
3.6
3.1
0.50
0.39
e6/l
0.24
80
523
75
401
2.14
7.09
3.2
3.1
2.14
2.72
e6/l
0.14
32
190
129
852
1.87
6.62
3.7
3.2
22.48
129.53
e6/l
0.78
93
657
142
967
1.86
6.61
4.4
3.9
80.06
80.75
e6/l
0.01
102
672
13
16
8.42
6.39
1.2
1.4
—
—
—
0
0
6
0
+∞
6.27
1.8
0.0
165.33
—
ng/l
—
6
0
59
307
2.14
5.91
2.0
1.9
1.92
1.77
%
0.49
54
275
11
15
7.56
5.18
1.2
1.0
—
—
—
0
0
62
349
1.97
4.99
3.5
5.0
1.00
1.05
mmol/l
1.01
62
317
14
29
5.00
4.87
1.4
1.2
36.60
25.66
g/l
2.13
14
24
98
644
1.76
4.83
1.2
1.3
—
—
—
0
0
15
42
3.70
4.82
2.6
3.3
3.74
4.51
e9/l
0.76
15
42
11
17
6.66
4.81
1.2
1.2
—
—
—
0
0
64
374
1.89
4.60
2.1
2.0
—
—
—
0
0
15
44
3.53
4.52
2.9
1.6
265.73
315.50
mu/l
0.35
15
38
17
55
3.21
4.43
2.9
2.9
56.59
60.18
%
0.73
17
55
12
25
4.95
4.23
1.3
1.3
—
—
—
0
0
17
59
2.99
3.96
1.5
2.0
4.80
4.77
mmol/24h
0.01
17
53
44
239
1.98
3.90
1.5
1.8
76.74
67.65
e9/l
0.61
27
179
10
20
5.13
3.72
2.5
2.5
1.25
0.17
%
—
10
15
40
214
2.00
3.70
3.4
4.1
0.08
0.06
%
0.09
13
36
20
80
2.60
3.62
1.4
2.0
138.38
131.44
g/l
—
8
61
10
22
4.66
3.46
1.3
1.1
—
—
—
0
0
13
37
3.62
3.44
2.2
3.7
—
—
—
0
0
88
610
1.62
3.41
1.7
1.6
1.75
1.06
mg/l
1.16
76
487
39
215
1.93
3.32
3.4
3.8
0.27
0.34
%
0.16
11
44
40
223
1.91
3.30
3.4
4.0
0.54
0.79
%
0.37
13
45
40
224
1.90
3.26
3.5
4.2
0.38
0.00
%
0.47
13
34
243
2129
1.63
3.24
35.0
17.2
14.10
13.57
%
5.63
243
2097
22
101
2.27
3.01
1.1
1.2
—
—
—
0
0
83
584
1.57
2.98
5.3
4.2
—
—
—
0
0
49
305
1.72
2.84
1.2
1.7
—
—
—
0
0
282
2601
1.85
2.74
27.8
13.9
30.92
22.59
mg/l
3.80
273
2081
46
288
1.70
2.61
1.3
1.3
—
—
—
0
0
10
31
3.30
2.54
1.1
1.5
92.04
89.67
%
—
10
31
7
18
3.95
2.26
1.3
1.1
—
—
—
0
0
41
262
1.65
2.17
1.2
1.4
—
—
—
0
0
81
605
1.46
2.15
3.0
2.5
7.29
6.88
e6/l
0.07
76
554
12
49
2.51
2.13
1.1
1.1
—
—
—
0
0
119
958
1.39
2.07
2.8
3.1
1096.50
1374.21
ng/l
0.52
103
811
19
100
1.96
1.90
1.1
1.2
—
—
—
0
0
74
558
1.43
1.85
3.9
4.2
1398.25
332.62
ng/l
0.77
60
444
5
12
4.22
1.83
1.0
1.3
—
—
—
0
0
13
60
2.22
1.80
2.5
1.5
0.89
0.84
nmol/l
0.13
13
47
36
235
1.60
1.78
1.2
1.5
—
—
—
0
0
6
18
3.38
1.75
1.2
1.0
—
—
—
0
0
31
196
1.65
1.73
4.7
3.4
—
—
—
0
0
33
214
1.61
1.68
1.1
1.2
—
—
—
0
0
8
31
2.62
1.67
1.0
1.2
—
—
—
0
0
7
25
2.84
1.66
1.1
1.4
—
—
—
0
0
6
20
3.04
1.59
2.0
1.8
17.18
17.02
%
—
6
20
7
27
2.63
1.52
1.6
1.7
—
—
—
0
0
6
21
2.89
1.51
2.2
1.5
6.58
8.39
mmol/l
—
6
21
13
66
2.01
1.45
1.9
1.7
—
—
—
0
0
5
17
2.97
1.36
2.0
3.2
—
—
—
0
0
28
185
1.56
1.34
3.9
3.3
5.23
5.18
kpa
0.14
28
176
5
18
2.81
1.29
1.0
1.1
—
—
—
0
0
9
45
2.03
1.24
1.6
1.3
0.68
0.66
nmol/l
—
9
40
8
40
2.03
1.13
1.0
1.1
—
—
—
0
0
52
404
1.34
1.10
1.6
1.2
—
—
—
0
0
257
2688
0.75
1.07
5.1
5.6
1.40
1.51
mmol/l
4.15
242
2463
246
2587
0.77
1.06
4.3
4.7
1.41
1.29
mmol/l
1.89
226
2346
46
353
1.36
1.06
1.4
1.5
—
—
—
0
0
111
1270
0.80
1.05
2.1
1.9
1.51
1.35
mmol/l
1.23
95
1076
9
46
1.98
1.04
1.0
1.1
—
—
—
0
0
9
47
1.94
1.03
1.0
1.4
—
—
—
0
0
9
49
1.86
0.99
1.4
1.4
—
—
—
0
0
9
49
1.86
0.99
1.4
1.4
—
—
—
0
0
9
49
1.86
0.99
1.4
1.4
—
—
—
0
0
19
124
1.57
0.99
4.6
3.4
—
—
—
0
0
9
50
1.82
0.97
1.4
1.5
—
—
—
0
0
83
700
1.25
0.96
2.6
2.3
360.85
348.38
umol/l
0.43
74
593
6
28
2.16
0.92
1.5
1.4
—
—
—
0
0
26
186
1.43
0.90
1.8
1.4
—
—
—
0
0
260
2702
0.78
0.87
5.1
5.7
4.48
4.67
mmol/l
2.15
247
2493
90
774
1.23
0.87
2.6
3.3
—
0.00
—
0
18
6
30
2.02
0.87
1.3
1.6
—
—
—
0
0
8
46
1.76
0.83
1.5
1.5
—
—
—
0
0
265
2743
0.78
0.81
5.9
6.6
2.56
2.71
mmol/l
1.99
249
2519
66
554
1.24
0.80
1.4
1.3
2.71
2.51
g/l
0.33
35
315
11
66
1.69
0.79
3.2
3.0
1.45
1.69
mg/l
0.43
11
59
8
48
1.68
0.79
1.0
1.1
—
—
—
0
0
102
900
1.20
0.76
3.0
2.3
70.56
63.04
u/l
0.38
94
836
37
291
1.31
0.75
4.1
3.6
7.38
7.39
ph
0.22
20
178
9
55
1.65
0.74
1.2
1.1
—
—
—
0
0
23
168
1.40
0.74
1.6
1.4
—
—
—
0
0
9
56
1.62
0.73
2.3
3.3
—
—
—
0
0
5
25
2.02
0.73
1.0
1.2
—
—
—
0
0
7
39
1.81
0.73
1.7
1.3
—
—
—
0
0
20
143
1.43
0.72
1.0
1.4
—
—
—
0
0
97
857
1.19
0.71
3.1
3.3
—
—
—
0
0
5
26
1.94
0.71
1.2
1.2
0.08
0.36
nmol/l
—
5
18
9
58
1.57
0.70
1.3
3.1
7.28
8.77
pmol/l
—
9
58
5
27
1.87
0.68
2.2
1.9
10.62
11.07
%
—
5
27
36
287
1.29
0.67
4.2
3.5
6.31
5.84
kpa
1.37
36
279
5
28
1.80
0.66
1.0
1.2
—
—
—
0
0
5
28
1.80
0.66
1.2
2.1
—
1.46
—
0
21
23
172
1.36
0.66
4.4
7.4
—
—
—
0
0
5
29
1.74
0.64
2.2
2.4
—
—
—
0
0
5
29
1.74
0.64
1.0
1.2
—
—
—
0
0
18
244
0.72
0.63
1.9
2.4
5.88
5.98
ph
0.51
12
165
6
102
0.58
0.63
28.0
9.7
—
—
—
0
0
58
675
0.83
0.62
4.0
4.3
1.02
1.02
kg/l
0.66
43
440
8
50
1.62
0.61
1.1
1.1
—
—
—
0
0
5
30
1.68
0.61
1.0
1.1
—
—
—
0
0
9
141
0.63
0.61
1.7
2.0
—
—
—
0
0
27
342
0.77
0.61
2.1
2.3
141.64
138.93
ug/g
0.02
22
269
139
1281
1.15
0.59
2.5
2.6
75.49
79.64
nmol/l
0.89
131
1128
188
1773
1.15
0.57
4.8
3.1
68.08
46.33
u/l
1.65
183
1643
21
159
1.34
0.57
2.2
2.4
—
—
—
0
0
6
37
1.63
0.56
1.5
1.6
—
—
—
0
0
46
388
1.22
0.55
1.3
1.4
386.67
570.53
titre
0.64
12
95
78
692
1.17
0.54
2.3
2.2
3.34
2.99
mg/l
0.22
67
585
11
76
1.46
0.48
1.2
1.4
276.28
312.75
ug/g
—
6
43
16
210
0.75
0.48
1.1
1.2
—
—
—
0
0
103
943
1.14
0.47
2.0
2.2
140.27
254.45
u/l
0.82
94
888
5
84
0.59
0.46
1.0
1.1
—
—
—
0
0
15
114
1.33
0.41
1.3
1.6
1.80
1.55
g/l
0.47
15
103
5
33
1.52
0.41
1.0
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
9.7
—
937.00
—
0
15
0
15
0.00
0.41
0.0
1.1
—
1.53
—
0
6
17
132
1.30
0.41
1.4
1.2
—
—
—
0
0
248
2547
0.87
0.40
5.8
5.7
1.72
1.94
mu/l
2.75
232
2319
0
18
0.00
0.40
0.0
3.9
—
31.64
—
0
11
262
2680
0.86
0.39
5.8
5.5
6.24
6.00
mmol/l
1.98
246
2427
0
19
0.00
0.39
0.0
1.1
—
2.48
—
0
9
156
1479
1.11
0.38
3.8
4.1
0.00
0.01
estimate
0.50
30
275
96
1036
0.89
0.38
3.4
3.6
—
—
—
0
0
9
68
1.33
0.38
2.4
1.3
0.98
0.91
g/l
—
9
68
80
872
0.89
0.37
1.7
1.7
20.01
20.84
nmol/l
0.19
70
737
5
37
1.36
0.37
1.0
1.1
—
24.75
—
0
11
63
694
0.88
0.35
4.4
4.4
1.56
1.98
ug/l
1.24
55
613
19
154
1.25
0.35
2.0
3.6
1.02
1.02
ratio
0.16
19
148
256
2616
0.88
0.33
7.1
7.1
40.72
39.83
mmol/mol
1.02
243
2432
224
2173
1.11
0.33
4.7
4.5
14.65
14.94
pmol/l
1.13
210
1971
36
410
0.86
0.32
2.6
2.9
0.56
0.76
ug/l
1.76
23
259
152
1451
1.09
0.31
3.8
4.0
0.00
0.00
estimate
-0.00
32
286
153
1463
1.09
0.30
3.8
4.1
0.00
0.00
estimate
-0.00
32
292
11
85
1.30
0.28
1.1
1.0
—
—
—
0
0
35
309
1.15
0.28
1.4
1.8
—
—
—
0
0
46
508
0.89
0.27
1.7
1.8
1087.98
1227.33
nmol/l
0.48
40
387
8
67
1.20
0.26
1.8
1.3
1.64
1.57
g/l
—
8
67
24
277
0.86
0.26
5.1
3.3
7.33
7.35
ph
0.12
17
186
33
293
1.14
0.25
1.4
1.4
—
—
—
0
0
57
618
0.91
0.25
1.5
1.8
481.09
453.73
pmol/l
0.32
45
510
138
1323
1.08
0.24
2.0
2.1
88.13
100.48
pmol/l
2.52
77
645
12
97
1.25
0.23
5.3
3.7
25.87
25.38
mmol/l
0.19
12
87
122
1168
1.07
0.22
3.9
3.9
21.56
87.95
ng/l
0.79
89
851
27
239
1.14
0.22
2.5
2.8
4.90
4.41
kpa
0.72
27
232
0
11
0.00
0.21
0.0
1.3
—
1.23
—
0
6
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
1441.00
—
0
12
0
12
0.00
0.21
0.0
1.2
—
37.42
—
0
6
0
12
0.00
0.21
0.0
7.3
—
24.86
—
0
12
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
77
812
0.93
0.19
4.5
4.0
0.00
0.00
estimate
-0.00
27
268
23
204
1.14
0.18
2.6
2.6
—
23.29
—
0
12
283
2858
0.90
0.18
39.9
21.5
4.46
4.49
e12/l
0.42
278
2773
283
2858
0.90
0.18
40.0
21.5
7.17
6.63
e9/l
4.08
278
2772
11
131
0.83
0.17
1.1
1.5
—
—
—
0
0
220
2161
1.06
0.16
35.5
18.5
328.64
331.64
g/l
5.63
220
2149
49
518
0.94
0.13
1.2
1.3
5.81
11.00
u/ml
0.46
15
200
18
200
0.89
0.13
2.4
3.0
126.89
130.59
g/l
0.27
18
193
64
667
0.95
0.11
1.3
1.3
1.53
1.75
u/ml
—
6
194
121
1241
0.96
0.11
2.6
2.9
143.70
112.65
ug/l
0.81
110
1152
108
1110
0.96
0.11
4.0
3.9
0.00
0.02
estimate
0.78
28
228
57
547
1.05
0.09
1.3
1.3
33.70
43.47
iu/ml
0.23
17
173
81
787
1.04
0.08
3.7
3.3
0.00
0.00
estimate
-0.00
27
229
5
64
0.78
0.08
1.0
1.5
—
—
—
0
0
104
1062
0.97
0.07
3.3
3.6
30.75
42.55
mg/l
0.57
66
651
12
132
0.91
0.06
1.1
1.1
—
—
—
0
0
115
1171
0.97
0.06
3.4
3.7
6.09
6.24
ph
0.74
60
661
17
182
0.93
0.06
1.1
1.2
87.45
111.68
u/ml
—
6
80
106
1074
0.98
0.03
4.0
4.3
8.14
8.22
mg/mmol
0.01
64
650
19
182
1.05
0.02
1.2
1.4
—
—
—
0
0
17
163
1.05
0.01
2.4
2.5
0.54
0.60
%
0.71
17
163
108
1082
1.00
0.00
3.2
3.5
7.13
7.09
mmol/l
0.03
97
920
10
97
1.03
0.00
1.6
1.7
—
—
—
0
0
10
97
1.03
0.00
1.1
1.3
—
2.96
—
0
16
17
167
1.02
0.00
2.4
2.5
1.22
1.17
%
0.09
17
167
272
2717
1.01
0.00
21.4
12.9
—
—
—
0
0
11
115
0.95
0.00
1.8
1.4
0.29
0.33
mg/l
—
5
41
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.6
—
5.71
—
0
7
0
8
0.00
-0.00
0.0
2.4
—
26.50
—
0
8
0
6
0.00
-0.00
0.0
7.8
—
7.05
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
9.1
—
4.87
—
0
8
7
78
0.90
-0.00
2.7
4.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
59.50
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
44.23
—
0
6
8
84
0.95
-0.00
1.1
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
-0.00
1.0
1.1
10.22
19.56
u/l
—
5
39
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
24.75
—
0
8

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_LUNG_NEUROENDO – Neuroendocrine tumor and carcinoma of lung

GWS hits: 1

This endpoint is excluded from FinRegistry analyses (omitted endpoint).