Background retinopathy and retinal vascular changes

H7_BCKRNDRETINOPAT

age-related macular degeneration: Age-related loss of vision in the central portion of the retina (macula), secondary to retinal degeneration.

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H35.0
  • Hospital discharge: ICD-9 3621|3624A
  • Hospital discharge: ICD-8 36701|37705|37709|37712
  • Cause of death: ICD-10 H35.0
  • Cause of death: ICD-9 3621|3624A
  • Cause of death: ICD-8 36701|37705|37709|37712

2 out of 7 registries used, show all original rules.

926

4. Check minimum number of events

None

926

5. Include endpoints

None

926

6. Filter based on genotype QC (FinnGen only)

810

Control definitions (FinnGen only)

Control exclude
H7_CHOROIDRETINA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF6
Parent code in ICD-10
H35
Name in latin
Retinopathia recessualis et commutationes vasculares retinae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6024 2953 3018
Only index persons 5178 2570 2608
Unadjusted period prevalence (%)
Whole population 0.08 0.08 0.08
Only index persons 0.10 0.09 0.10
Median age at first event (years)
Whole population 59.07 63.57 54.72
Only index persons 58.11 62.71 53.57

-FinnGen-

Key figures

All Female Male
Number of individuals 810 388 422
Unadjusted period prevalence (%) 0.17 0.14 0.19
Median age at first event (years) 59.10 59.71 58.53

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
844
Matched controls
8440
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
4503599627370496.0
307.7
747
*
XCK10
NOMESCO Finland
Photography of fundus of eye
13.8
261.1
291
311
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
20.2
259.0
217
142
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
14.8
246.7
254
239
XCW99
NOMESCO Finland
Other investigative procedure of eye
12.1
213.8
252
287
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
277.3
195.6
193
9
H43.1
ICD-10 Finland
Vitreous haemorrhage
44.1
195.2
118
31
CKC12
NOMESCO Finland
Photocoagulation of retina
330.7
186.0
182
7
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
39.8
183.7
114
33
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
42.0
180.0
110
30
A10AA02, ,
ATC
20.7
166.4
132
75
A10AB01
ATC
insulin (human); parenteral
20.7
159.3
126
71
A10AC01
ATC
insulin (human); parenteral
9.3
151.9
211
291
A10AA01, ,
ATC
26.8
150.5
106
45
T89
ICPC
Diabetes insulin dependent
15.9
149.3
136
101
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
34.3
142.6
92
30
Z01.0
ICD-10 Finland
Examination of eyes and vision
6.2
136.7
323
772
A10AB04
ATC
insulin lispro; parenteral
18.6
130.8
108
66
A10AE04
ATC
insulin glargine; parenteral
7.3
127.8
226
405
A10AB05
ATC
insulin aspart; parenteral
8.3
127.3
192
289
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
14.4
125.7
120
96
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
16.9
118.9
103
69
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
228.2
116.9
118
6
XCH00
NOMESCO Finland
Eye pressure measurement
10.9
109.3
126
134
H04AA01
ATC
glucagon; nasal, parenteral
26.0
107.6
76
32
XCD20
NOMESCO Finland
Photoangiography of eye
208.2
107.2
109
6
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
26.5
106.9
75
31
A10AE05
ATC
insulin detemir; parenteral
9.1
106.9
143
185
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
158.1
94.3
98
7
WX140
NOMESCO Finland
Parabulbar anesthesy
14.3
93.5
88
68
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
7.8
91.8
139
207
CKC10
NOMESCO Finland
Local photocoagulation of retina
493.5
91.1
89
*
Z96.1
ICD-10 Finland
Presence of intraocular lens
5.0
89.7
245
640
H36.01
ICD-10 Finland
Diabetic maculopathy
328.8
88.5
88
*
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
38.7
82.3
51
14
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
12.7
79.3
80
69
H34.8
ICD-10 Finland
Other retinal vascular occlusions
419.6
78.2
77
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
12.2
78.1
81
73
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
808.1
76.5
74
*
H3601, E113,
ICD-10 Finland
+∞
76.2
72
*
103
Kela drug reimbursment
Diabetes, insulin-treated
3.7
76.1
390
1582
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
43.2
74.7
45
11
215
Kela drug reimbursment
Diabetes, non-insulin-treated
3.7
72.5
347
1339
Z94.0
ICD-10 Finland
Kidney transplant status
22.1
72.2
54
26
H36.00
ICD-10 Finland
Diabetic background retinopathy
736.6
70.1
68
*
A10AE06
ATC
insulin degludec; parenteral
9.2
69.8
89
107
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
22.1
69.5
52
25
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
12.2
69.0
71
63
H3603, E103,
ICD-10 Finland
+∞
64.4
61
*
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
26.6
61.8
43
17
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
23.2
60.0
44
20
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
18.8
59.8
48
27
127
Kela drug reimbursment
Transplant complication
14.3
59.3
55
41
E10
ICD-10 Finland
Type 1 diabetes mellitus
18.4
57.9
47
27
A11CC03
ATC
alfacalcidol; systemic
9.1
56.5
72
86
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
5.0
55.6
133
304
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
19.6
54.7
43
23
H33.0
ICD-10 Finland
Retinal detachment with retinal break
562.5
54.2
53
*
A10AD01
ATC
insulin (human); parenteral
14.4
53.2
49
36
A12AA04
ATC
calcium carbonate; oral
12.2
52.9
54
47
137
Kela drug reimbursment
Uraemia requiring dialysis
20.9
52.4
40
20
H3600, E103,
ICD-10 Finland
+∞
51.6
49
*
XCK00
NOMESCO Finland
Perimetry
5.6
50.8
103
203
Z3229
NOMESCO Finland
Other healthcare associate professional
4.5
49.5
137
351
CKC15
NOMESCO Finland
Panretinal photocoagulation
138.3
49.4
52
*
L04AA06
ATC
mycophenolic acid; systemic
10.8
48.9
54
53
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.9
48.0
384
1907
H3603, E113,
ICD-10 Finland
+∞
47.3
45
*
Z49.0
ICD-10 Finland
Preparatory care for dialysis
15.9
47.1
41
27
TK800
NOMESCO Finland
Hemodialysis
8.8
46.3
60
73
L04AD02
ATC
tacrolimus; systemic
16.3
45.4
39
25
H3600, E113,
ICD-10 Finland
+∞
45.2
43
*
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
17.5
44.7
37
22
N18.0
ICD-10 Finland
End-stage renal disease
14.9
44.5
40
28
H3601, E103,
ICD-10 Finland
+∞
44.1
42
*
Z49.1
ICD-10 Finland
Extracorporeal dialysis
12.5
44.0
44
37
S01EC01
ATC
acetazolamide; systemic
9.5
43.8
53
59
N18.8
ICD-10 Finland
Other chronic renal failure
8.7
43.6
57
70
XCW10
NOMESCO Finland
Assessment of vision
14.4
43.6
40
29
Z13.1
ICD-10 Finland
Special screening examination for diabetes mellitus
9.5
42.0
51
57
S01BC03
ATC
diclofenac; ophthalmic
9.5
42.0
51
57
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.7
41.3
374
1943
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
220.7
41.2
42
*
177
Kela drug reimbursment
Insulin glargine 300 U / ml
10.5
41.0
46
46
H26.4
ICD-10 Finland
After-cataract
3.8
40.7
141
423
XCD10
NOMESCO Finland
Electrophysiological examination of eye
8.6
40.6
53
65
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
79.3
40.3
45
6
ZXA10
NOMESCO Finland
Bilateral
3.0
40.1
222
890
CKD40
NOMESCO Finland
Endophotocoagulation of retina
405.5
39.4
39
*
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
11.3
38.5
41
38
B03XA02
ATC
darbepoetin alfa; parenteral
8.2
38.2
52
67
V03AE01
ATC
polystyrene sulfonate; oral
11.0
37.8
41
39
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
13.4
37.6
36
28
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
136.1
37.0
39
*
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
51.4
37.0
44
9
H33.3
ICD-10 Finland
Retinal breaks without detachment
372.5
36.3
36
*
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
193.2
36.1
37
*
CL2S4
NOMESCO Finland
Ocular fundus photography for diabetic retinopathy screening
8.0
36.0
50
66
H35.6
ICD-10 Finland
Retinal haemorrhage
+∞
35.7
34
*
H35.8
ICD-10 Finland
Other specified retinal disorders
+∞
35.7
34
*
C03CA01
ATC
furosemide; systemic
2.5
35.6
370
2018
C02AC05
ATC
moxonidine; oral
4.5
34.2
88
211
205
Kela drug reimbursment
Chronic hypertension
2.5
34.0
320
1661
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
36.7
33.1
42
12
CJB10
NOMESCO Finland
Laser discission of secondary cataract
3.8
32.9
110
320
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
+∞
32.5
31
*
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
5.1
31.2
69
146
SPAT1262
SPAT
Handing over of treatment supplies
2.7
30.9
202
874
H35.7
ICD-10 Finland
Separation of retinal layers
+∞
30.4
29
*
C08CA01
ATC
amlodipine; oral
2.3
30.4
408
2444
C09AA02
ATC
enalapril; systemic
2.6
30.3
238
1125
H25.1
ICD-10 Finland
Senile nuclear cataract
2.4
30.1
304
1612
I10
ICD-10 Finland
Essential (primary) hypertension
2.4
30.0
602
4262
S01ED51
ATC
timolol, combinations; ophthalmic
3.7
29.7
101
297
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
5.4
29.6
61
121
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
40.5
28.2
35
9
T90
ICPC
Diabetes non-insulin dependent
2.4
28.0
264
1351
H36.02
ICD-10 Finland
Preproliferative diabetic retinopathy
+∞
27.2
26
*
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.3
27.0
278
1474
H3603, E106,
ICD-10 Finland
+∞
26.2
25
*
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
62.1
26.1
30
5
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
32.1
26.1
34
11
H3601, H350,
ICD-10 Finland
+∞
25.1
24
*
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.8
24.5
140
560
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
32.1
23.8
31
10
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
246.7
23.8
24
*
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
128.7
23.7
25
*
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
55.7
23.2
27
5
H35.36
ICD-10 Finland
Macular cyst
+∞
23.0
22
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
22.6
462
3138
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
28.2
22.4
30
11
H43.8
ICD-10 Finland
Other disorders of vitreous body
3.0
22.2
105
378
B01AC04
ATC
clopidogrel; oral
2.3
22.1
197
970
H25.8
ICD-10 Finland
Other senile cataract
2.8
22.1
127
508
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.0
22.0
388
2492
H35.9
ICD-10 Finland
Retinal disorder, unspecified
64.3
22.0
25
*
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
22.9
21.8
31
14
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
225.6
21.7
22
*
H36.09
ICD-10 Finland
Diabetic retinopathy (E10-E14+ with common fourth character .3)
118.1
21.7
23
*
B05DA
ATC
Isotonic solutions
19.5
21.4
32
17
B05DB
ATC
Hypertonic solutions
21.4
21.4
31
15
CKC20
NOMESCO Finland
Cryopexy of undetached retina
215.1
20.7
21
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.4
20.7
80
255
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
33.5
20.3
26
8
C10AA01
ATC
simvastatin; oral
2.0
20.3
406
2703
C10AA05
ATC
atorvastatin; oral
2.0
20.2
404
2687
V03AE02
ATC
sevelamer; oral
27.8
20.1
27
10
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.6
20.1
135
583
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.1
20.0
257
1461
H3601, E116,
ICD-10 Finland
+∞
19.9
19
*
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
75.3
19.8
22
*
H26.02
ICD-10 Finland
Presenil cataract
5.2
19.7
41
82
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
22.2
19.6
28
13
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.5
19.6
143
642
Z3231
NOMESCO Finland
Registered nurse
2.1
19.4
259
1490
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
4.2
19.2
52
129
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.1
19.2
249
1416
C07AB07
ATC
bisoprolol; oral
1.9
19.2
469
3316
WX002
NOMESCO Finland
Sedation and analgesia
2.2
19.1
186
945
J01FF01
ATC
clindamycin; systemic
2.1
19.1
254
1457
OAB50, ,
SPAT
2.9
19.0
98
369
Z49.2
ICD-10 Finland
Other dialysis
17.6
18.8
29
17
A10AD05
ATC
insulin aspart; parenteral
5.8
18.8
35
63
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
71.6
18.8
21
*
ZXA00
NOMESCO Finland
Right side
2.0
18.6
255
1477
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
4.1
18.6
53
137
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.6
18.3
114
474
A10BB01
ATC
glibenclamide; oral
3.7
18.2
59
167
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.0
17.8
239
1370
196
Kela drug reimbursment
Paricalcitol and cinacalcet
23.4
17.8
25
11
CKD15
NOMESCO Finland
Injection of vitreous substitute
+∞
17.8
17
*
2500A
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE,TYYPPI II]
4.7
17.7
41
90
S01ED01
ATC
timolol; ophthalmic
4.1
17.7
49
124
H35.37
ICD-10 Finland
Macular holes
183.7
17.6
18
*
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
19.1
17.4
26
14
H26.2
ICD-10 Finland
Complicated cataract
16.4
17.1
27
17
CK2M4
NOMESCO Finland
Macular light layer imaging (OCT)
32.2
17.1
22
7
A10BA02
ATC
metformin; oral
1.9
16.8
280
1727
H3603, H350,
ICD-10 Finland
+∞
16.7
16
*
S01EA05
ATC
brimonidine; ophthalmic
4.8
16.7
38
82
NHQ40
NOMESCO Finland
Amputation of toe
5.7
16.6
31
56
C08CA13
ATC
lercanidipine; oral
2.2
16.2
153
765
H20.1
ICD-10 Finland
Chronic iridocyclitis
17.1
16.2
25
15
C08CA02
ATC
felodipine; oral
2.5
16.1
111
483
V03AE03
ATC
lanthanum carbonate; oral
25.0
16.1
22
9
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.7
16.0
90
354
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.1
16.0
181
971
ZXA05
NOMESCO Finland
Left side
2.0
15.9
230
1347
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
3.3
15.8
62
199
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.3
15.8
131
620
36701
ICD-8 Finland
Inflammation of optic nerve and retina, Periphlebitis retinae
+∞
15.7
15
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.9
15.6
75
271
CM2X4
NOMESCO Finland
Follow-up OCT of age-related macular degeneration lesions
162.9
15.5
16
*
S01EC03
ATC
dorzolamide; ophthalmic
6.2
15.2
26
43
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
4.2
15.1
41
102
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
45.9
15.1
18
*
C10AX09
ATC
ezetimibe; oral
2.1
15.1
164
865
H02AB04
ATC
methylprednisolone; systemic
2.2
15.0
142
709
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
6.6
15.0
24
37
A10BB12
ATC
glimepiride; oral
2.7
14.9
85
337
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
11.6
14.8
27
24
CKD20
NOMESCO Finland
Removal of vitreous body substitute
+∞
14.6
14
*
37709
ICD-8 Finland
Other diseases of retina and optic nerve, Laesio vascularis retinae NUD
+∞
14.6
14
*
H35.4
ICD-10 Finland
Peripheral retinal degeneration
81.6
14.6
16
*
S01EE01
ATC
latanoprost; ophthalmic
2.9
14.5
71
259
ZX120
NOMESCO Finland
Intravenous
2.5
14.3
98
425
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
6.3
14.3
24
39
KA1AE
NOMESCO Finland
Kidney ultrasound examination
4.3
14.3
37
89
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.5
14.0
49
146
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
13.8
165
898
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
10.7
13.8
26
25
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
3.9
13.7
40
105
S97
ICPC
Chronic ulcer skin
2.7
13.7
74
285
CK9G4
NOMESCO Finland
Iridocyanine green angiography (ICGA) of choroid and retina
+∞
13.6
13
*
1LA05, ,
NOMESCO Finland
+∞
13.6
13
*
H3601, E106,
ICD-10 Finland
+∞
13.6
13
*
H33.1
ICD-10 Finland
Retinoschisis and retinal cysts
+∞
13.6
13
*
H33.4
ICD-10 Finland
Traction detachment of retina
+∞
13.6
13
*
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
16.5
13.5
21
13
CM2S4
NOMESCO Finland
Follow-up photography of age-related macular degeneration lesions
142.2
13.5
14
*
H34.2
ICD-10 Finland
Other retinal artery occlusions
142.2
13.5
14
*
S01EC04
ATC
brinzolamide; ophthalmic
3.5
13.5
47
140
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
4.3
13.3
35
85
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
28.9
13.0
17
6
L28
ICPC
Limited function/disability (L)
1.9
12.9
188
1094
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.8
12.8
239
1505
114
Kela drug reimbursment
Glaucoma
2.4
12.8
90
394
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
32.6
12.6
16
5
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
17.6
12.6
19
11
H3602, E103,
ICD-10 Finland
+∞
12.5
12
*
CK2K4
NOMESCO Finland
Red-free imaging of ocular fundus
+∞
12.5
12
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.9
12.5
184
1074
ZXD10
NOMESCO Finland
Scheduled procedure
1.7
12.4
318
2192
H40.0
ICD-10 Finland
Glaucoma suspect
2.5
12.4
79
331
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
4.3
12.3
32
77
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
12.3
203
1229
B03XA01
ATC
erythropoietin; parenteral
10.7
12.3
23
22
C01DA14
ATC
isosorbide mononitrate; oral
2.0
12.3
166
941
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
4.4
12.3
31
73
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
3.0
12.2
56
197
C02CA01
ATC
prazosin; oral
5.0
12.2
26
53
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.8
12.2
223
1394
C09CA06
ATC
candesartan; oral
1.8
12.1
211
1299
SPAT1254
SPAT
Administration of medicine
2.0
11.9
139
748
I50.9
ICD-10 Finland
Heart failure, unspecified
1.9
11.9
163
928
H05BX01
ATC
cinacalcet; oral
11.9
11.9
21
18
ZX198
NOMESCO Finland
Other local administration
11.9
11.9
21
18
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
6.0
11.8
21
36
S01EA03
ATC
apraclonidine; ophthalmic
10.7
11.8
22
21
L04AD01
ATC
ciclosporin; systemic
5.2
11.8
24
47
D64.9
ICD-10 Finland
Anaemia, unspecified
2.1
11.8
114
572
TK820
NOMESCO Finland
Peritoneal dialysis
16.7
11.7
18
11
R4120
NOMESCO Finland
Occupational therapy
2.6
11.7
68
272
A10AA03, ,
ATC
12.8
11.7
20
16
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.8
11.5
60
227
H30.9
ICD-10 Finland
Chorioretinal inflammation, unspecified
+∞
11.5
11
*
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
+∞
11.5
11
*
H34.9
ICD-10 Finland
Retinal vascular occlusion, unspecified
+∞
11.5
11
*
J01DB01
ATC
cefalexin; oral
1.9
11.5
680
5823
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.1
11.5
118
606
H25.0
ICD-10 Finland
Senile incipient cataract
2.7
11.3
63
247
J01MA02
ATC
ciprofloxacin; systemic
1.7
11.2
337
2407
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.5
11.2
72
302
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.8
11.2
190
1157
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.0
11.0
128
687
AA1AD
NOMESCO Finland
CT of head and brain
1.7
11.0
263
1768
E87.5
ICD-10 Finland
Hyperkalaemia
4.2
10.9
29
71
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
10.8
253
1688
S01BC05
ATC
ketorolac; ophthalmic
3.1
10.7
46
156
H53.4
ICD-10 Finland
Visual field defects
4.2
10.7
28
68
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.6
10.7
63
254
E11.6
ICD-10 Finland
Type 2 diabetes mellitus, with other specified complications
4.0
10.6
30
77
L04AA01
ATC
[U] ciclosporin
8.1
10.6
23
29
H35.29
ICD-10 Finland
Other proliferative retinopathy
+∞
10.4
10
*
H34.1
ICD-10 Finland
Central retinal artery occlusion
+∞
10.4
10
*
H360, E103,
ICD-10 Finland
+∞
10.4
10
*
C09CA01
ATC
losartan; oral
1.7
10.4
228
1494
RS221, ,
NOMESCO Finland
5.2
10.4
21
41
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.9
10.3
161
953
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
10.8
10.3
19
18
D31.3
ICD-10 Finland
Benign neoplasm: Choroid
5.0
10.3
22
45
A10BK01
ATC
dapagliflozin; oral
2.3
10.1
77
349
R06.0
ICD-10 Finland
Dyspnoea
1.7
10.1
245
1646
A10BH01
ATC
sitagliptin; oral
2.2
10.1
90
437
SPAT1301
SPAT
No procedures
1.7
10.1
256
1742
M14.6*A52.1
ICD-10 Finland
Charcot's or tabetic arthropathy
40.6
10.0
12
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
10.0
189
1186
C08CA10
ATC
nilvadipine; oral
4.3
9.9
25
59
H19.3*M35.0
ICD-10 Finland
Keratoconjunctivitis sicca
26.4
9.8
13
5
2504B
ICD-9 Finland
Diabetes mellitus, Diabetes with renal manifestations[DIABETES MELLITUS CUM COMPLICATIONE OCULI ,TYYPPI I]
26.4
9.8
13
5
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
20.3
9.8
14
7
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
20.3
9.8
14
7
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
4.8
9.8
22
47
BEF00, ,
SPAT
9.7
9.8
19
20
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
9.8
289
2040
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.5
9.8
63
265
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.4
9.8
71
316
R4190
NOMESCO Finland
Nutritional therapy
3.0
9.7
42
143
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
13.6
9.7
16
12
FN2BA
NOMESCO Finland
Percutaneous transluminal coronary angioplasty with stent (includes balloon pre-dilation)
2.4
9.7
66
285
WZC30
NOMESCO Finland
Teaching
1.9
9.7
144
839
M14.6*E10.6
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic neuropathic
55.6
9.7
11
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.9
9.6
128
719
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.7
9.6
50
189
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.0
9.6
118
645
H16.0
ICD-10 Finland
Corneal ulcer
2.7
9.6
53
207
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
9.2
9.6
19
21
G63.2
ICD-10 Finland
Diabetic polyneuropathy
15.2
9.5
15
10
H04.10
ICD-10 Finland
Dry eye syndrome
2.1
9.5
99
510
J01MA12
ATC
levofloxacin; systemic
1.8
9.5
167
1025
2501B
ICD-9 Finland
Diabetes mellitus, Diabetes with ketoacidosis[DIABETES MELLITUS CUM KETOACIDOSI ,TYYPPI I]
101.1
9.4
10
*
H28.0*E10.3
ICD-10 Finland
Other specified diabetes mellitus - Diabetic cataract
101.1
9.4
10
*
171
Kela drug reimbursment
Degludekinsuliini
30.4
9.4
12
*
L04AX01
ATC
azathioprine; systemic
3.0
9.4
42
146
I12.0
ICD-10 Finland
Hypertensive renal disease with renal failure
5.2
9.4
19
37
3621A
ICD-9 Finland
Other retinal disorders, Other background retinopathy and retinal vascular changes
+∞
9.4
9
*
H35.5
ICD-10 Finland
Hereditary retinal dystrophy
+∞
9.4
9
*
CKC30
NOMESCO Finland
Cryopexy of detached retina
+∞
9.4
9
*
H33.2
ICD-10 Finland
Serous retinal detachment
+∞
9.4
9
*
3624A
ICD-9 Finland
Other retinal disorders, Separation of retinal layers[RETINOPATHIA CENTRALIS SEROSA]
+∞
9.4
9
*
37712
ICD-8 Finland
Other diseases of retina and optic nerve, Retinitis exsudativa externa (Coats)
+∞
9.4
9
*
TQW11
NOMESCO Finland
Vacuum treatment of wound
3.8
9.4
28
75
S91.1
ICD-10 Finland
Open wound of toe(s) without damage to nail
5.0
9.3
20
41
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.5
9.3
59
246
321
Kela drug reimbursment
Paricalcitol and cinacalcet
9.7
9.3
18
19
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.9
9.2
43
153
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.2
9.2
80
384
A46
ICD-10 Finland
Erysipelas
1.9
9.2
137
798
C09AA05
ATC
ramipril; oral
1.7
9.2
229
1545
CS494
NOMESCO Finland
Other visual field testing
3.7
9.2
29
81
WX872
NOMESCO Finland
Intensive care
2.6
9.1
55
224
N19
ICD-10 Finland
Unspecified kidney failure
2.8
9.1
46
171
H02AB06
ATC
prednisolone; systemic
1.6
9.1
391
3002
I50.0
ICD-10 Finland
Congestive heart failure
2.2
9.1
83
406
25009
ICD-8 Finland
Diabetes mellitus, Unspecified
24.3
8.9
12
5
RD210, ,
NOMESCO Finland
4.7
8.9
20
43
S18
ICPC
Laceration/cut
1.6
8.8
384
2952
H53.1
ICD-10 Finland
Subjective visual disturbances
2.4
8.8
62
272
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.6
8.8
279
1995
A02BC02
ATC
pantoprazole; systemic
1.6
8.7
556
4645
Z71.8
ICD-10 Finland
Other specified counselling
1.6
8.7
262
1847
E14.9
ICD-10 Finland
Unspecified diabetes mellitus, without complications
4.3
8.7
22
52
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
1.7
8.7
179
1146
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.1
8.6
80
394
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.8
8.6
134
790
R60.0
ICD-10 Finland
Localized oedema
1.9
8.6
111
616
ZXE00
NOMESCO Finland
One hour or less
1.6
8.6
305
2236
U14
ICPC
Kidney symptom/complaint
4.1
8.6
23
57
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.9
8.6
112
625
A12AA12
ATC
[U] calcium acetate
27.8
8.5
11
*
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
2.7
8.5
45
172
Z95.1
ICD-10 Finland
Presence of aortocoronary bypass graft
2.6
8.5
49
196
CKD95
NOMESCO Finland
Extended combined vitectomy and lens procedure through pars plana
90.9
8.4
9
*
H30.8
ICD-10 Finland
Other chorioretinal inflammations
+∞
8.3
8
*
H3601, E118,
ICD-10 Finland
+∞
8.3
8
*
H360, E113,
ICD-10 Finland
+∞
8.3
8
*
H3603, E107,
ICD-10 Finland
+∞
8.3
8
*
ZXD05
NOMESCO Finland
Urgent procedure
1.6
8.3
251
1769
XF400
NOMESCO Finland
ECG with 12 standard connections
1.8
8.3
142
862
WX199
NOMESCO Finland
Other local analgesia
3.0
8.2
36
124
A10AB06
ATC
insulin glulisine; parenteral
7.6
8.2
18
24
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.5
8.2
53
224
TPX10
NOMESCO Finland
Implantation of vascular injection port
3.1
8.1
34
114
Z96.4
ICD-10 Finland
Presence of endocrine implants
33.7
8.1
10
*
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.8
8.1
140
852
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.4
8.1
55
238
J01MA14
ATC
moxifloxacin; systemic
2.1
8.0
83
426
L17
ICPC
Foot/toe symptom/complaint
1.6
8.0
243
1711
XF402
NOMESCO Finland
ECG with work load test
2.0
8.0
95
512
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.6
8.0
230
1600
M86.9
ICD-10 Finland
Osteomyelitis, unspecified
7.3
8.0
18
25
WX202
NOMESCO Finland
Supraclavicular plexus blockade
4.3
8.0
20
47
N03AX16
ATC
[U] pregabalin
1.7
7.9
187
1241
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
3.1
7.8
33
111
TK810
NOMESCO Finland
Hemofiltration
8.6
7.8
16
19
3025
Kela drug reimbursment
Calcium carbonate
9.5
7.8
15
16
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
7.8
217
1497
N18.4
ICD-10 Finland
Chronic kidney disease, stage 4
6.5
7.7
19
30
N02AX02
ATC
tramadol; systemic, rectal
1.5
7.7
355
2738
C07AB02
ATC
metoprolol; systemic
1.7
7.7
176
1155
XF600
NOMESCO Finland
Bloodpressure measurement
2.3
7.7
57
256
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.6
7.7
186
1239
PD4BC
NOMESCO Finland
Extensive arterigography of lower extremity with X-ray
4.0
7.6
21
53
N02BE01
ATC
paracetamol; systemic, rectal
1.8
7.6
729
6589
H57.1
ICD-10 Finland
Ocular pain
2.9
7.6
35
124
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.0
7.6
89
479
SPAT1325
SPAT
Vaccination
1.5
7.5
261
1892
H16.9
ICD-10 Finland
Keratitis, unspecified
4.3
7.5
19
45
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
3.5
7.4
25
73
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
3.4
7.4
26
78
D31.2
ICD-10 Finland
Benign neoplasm: Retina
80.8
7.4
8
*
C09BA02
ATC
enalapril and diuretics; systemic
2.1
7.4
74
375
WX892
NOMESCO Finland
Monitored bed care
2.1
7.4
75
382
K65.0
ICD-10 Finland
Acute peritonitis
6.0
7.4
19
32
H60.9
ICD-10 Finland
Otitis externa, unspecified
2.2
7.3
63
301
Z2221
NOMESCO Finland
Medical doctor
1.6
7.3
211
1464
ZYC01
NOMESCO Finland
Remote contact by phone
2.3
7.3
56
255
B80
ICPC
Iron deficiency anaemia
3.2
7.3
28
89
SPAT1263
SPAT
Sampling
1.5
7.3
319
2426
H3601, E119,
ICD-10 Finland
+∞
7.3
7
*
QDH
NOMESCO Finland
Operations on toe nails
+∞
7.3
7
*
H21.1
ICD-10 Finland
Other vascular disorders of iris and ciliary body
+∞
7.3
7
*
H3602, E113,
ICD-10 Finland
+∞
7.3
7
*
H3603, E116,
ICD-10 Finland
+∞
7.3
7
*
A41.8
ICD-10 Finland
Other specified sepsis
3.5
7.3
25
74
A28
ICPC
Limited function/disability NOS
1.7
7.3
163
1064
H53.9
ICD-10 Finland
Visual disturbance, unspecified
2.8
7.2
36
134
E16.0
ICD-10 Finland
Drug-induced hypoglycaemia without coma
20.2
7.1
10
5
C07AG02
ATC
carvedilol; oral
2.2
7.1
62
298
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.9
7.1
92
511
S91.3
ICD-10 Finland
Open wound of other parts of foot
3.1
7.1
29
96
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.0
7.1
80
424
NHQ30
NOMESCO Finland
Amputation of foot, transmetatarsal
12.2
7.1
12
10
R80
ICD-10 Finland
Isolated proteinuria
12.2
7.1
12
10
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
12.2
7.1
12
10
Z2446
NOMESCO Finland
Social worker
2.2
7.1
59
279
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
10.1
7.0
13
13
F01
ICPC
Eye pain
3.0
7.0
30
102
E66.01
ICD-10 Finland
Obesity due to excess calories
2.0
7.0
71
362
S01BA07
ATC
fluorometholone; ophthalmic
5.5
6.9
19
35
S92.3
ICD-10 Finland
Fracture of metatarsal bone
2.8
6.9
34
125
I21.4
ICD-10 Finland
Acute subendocardial myocardial infarction
4.0
6.9
19
48
K08.3
ICD-10 Finland
Retained dental root
2.1
6.9
69
350
WX142
NOMESCO Finland
Sub-tenon anesthesy
13.9
6.9
11
8
M86.6
ICD-10 Finland
Other chronic osteomyelitis
13.9
6.9
11
8
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
6.8
543
4628
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.1
6.8
28
93
SPAT1100
SPAT
Long-term monitoring of blood pressure
2.2
6.8
59
284
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
6.7
233
1684
H18.2
ICD-10 Finland
Other corneal oedema
22.7
6.7
9
*
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
2.1
6.7
62
306
SPAT1097
SPAT
Recording of ECG
1.7
6.6
119
730
S01EC54
ATC
brinzolamide, combinations; ophthalmic
6.0
6.6
17
29
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
6.6
235
1705
S01FA01
ATC
atropine; ophthalmic
12.4
6.6
11
9
3AC01, ,
NOMESCO Finland
6.9
6.5
15
22
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
6.3
6.5
16
26
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.8
6.5
91
519
N18.3
ICD-10 Finland
Chronic kidney disease, stage 3
3.2
6.5
25
80
B07.9
ICD-10 Finland
Verruca simplex
2.7
6.5
33
124
R20.2
ICD-10 Finland
Paraesthesia of skin
2.1
6.4
58
283
N08.3
ICD-10 Finland
Glomerular disorders in diabetes mellitus
70.4
6.4
7
*
3643
FHL
Vitrectomy through pars Plana
70.4
6.4
7
*
A10BK03
ATC
empagliflozin; oral
1.8
6.4
90
513
AN1
HP
Coronary angiography
1.8
6.4
100
590
QDB10, ,
SPAT
2.8
6.4
30
108
O80.0
ICD-10 Finland
Spontaneous vertex delivery
0.4
6.4
27
685
GD1AD
NOMESCO Finland
Thorax CT examination
2.1
6.3
63
319
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
2.8
6.3
31
114
JN3AD
NOMESCO Finland
Abdominal CT examination
1.7
6.3
109
661
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.3
6.3
49
225
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
11.1
6.3
11
10
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
6.3
229
1667
TPH07
NOMESCO Finland
Cathetrisation of artery
1.8
6.3
98
577
S29
ICPC
Skin symptom/complaint other
1.6
6.3
155
1034
TJA33
NOMESCO Finland
Percutaneous introduction of peritoneal dialysis catheter
18.2
6.3
9
5
N083, E102,
ICD-10 Finland
+∞
6.3
6
*
JL9AE
NOMESCO Finland
Ultrasound examination of pancreas transplant
+∞
6.3
6
*
CKC70
NOMESCO Finland
Circular buckling of sclera
+∞
6.3
6
*
37700
ICD-8 Finland
Other diseases of retina and optic nerve, Haemorrhagia corporis vitrei
+∞
6.3
6
*
3792A
ICD-9 Finland
Other disorders of eye, Disorders of vitreous body
+∞
6.3
6
*
H30.2
ICD-10 Finland
Posterior cyclitis
+∞
6.3
6
*
M14.6
ICD-10 Finland
Neuropathic arthropathy
+∞
6.3
6
*
JLE03
NOMESCO Finland
Allogenic total transplantation of pancreas with pancreaticoenterostomy
+∞
6.3
6
*
H3601, H547,
ICD-10 Finland
+∞
6.3
6
*
CK2Y4
NOMESCO Finland
OCT video recording of ocular fundus
+∞
6.3
6
*
R4110
NOMESCO Finland
Physiotherapy
1.5
6.2
219
1583
K29
ICPC
Cardiovascular sympt/complt other
2.5
6.2
38
157
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.9
6.2
81
452
Z02.7
ICD-10 Finland
Issue of medical certificate
2.0
6.1
62
316
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
2.7
6.1
31
116
C03AA03
ATC
hydrochlorothiazide; oral
1.9
6.1
78
431
CBB30
NOMESCO Finland
Excision of lesion of eyelid
3.1
6.1
25
83
J01DA01
ATC
[U] cefalexin
1.4
6.1
477
4012
DFF00
NOMESCO Finland
Pure tone audiometry
1.8
6.1
88
506
R4180, ,
SPAT
4.2
6.1
16
39
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
12.6
6.1
10
8
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.2
6.1
48
222
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
6.1
271
2054
E11.1
ICD-10 Finland
Type 2 diabetes mellitus, with ketoacidosis
8.7
6.1
12
14
H47.1
ICD-10 Finland
Papilloedema, unspecified
8.7
6.1
12
14

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
470
2373
3.21
60.65
7.4
4.0
28.24
7.33
mg/mmol
7.24
355
1540
453
2324
3.05
55.32
6.6
3.4
131.68
42.97
mg/l
5.79
350
1547
465
2452
3.00
53.47
6.6
3.3
6.45
7.76
mmol/l
11.68
412
2094
175
567
3.63
45.35
9.3
3.9
148.00
90.64
ng/l
6.15
164
493
192
680
3.36
43.13
21.2
6.9
13.07
10.36
mmol/l
5.01
183
649
35
22
16.55
41.10
2.5
1.7
—
—
—
0
0
249
1089
2.82
38.14
6.1
2.6
21.49
22.40
%
0.47
238
1017
260
1173
2.76
37.42
6.0
2.5
2.22
2.28
g/l
0.92
245
1088
271
1260
2.70
36.65
6.0
2.6
11.39
12.64
umol/l
2.48
257
1177
196
795
2.91
34.17
9.3
3.5
7.36
7.38
ph
3.69
135
473
226
995
2.74
33.67
20.0
5.7
1.15
1.02
mmol/l
7.41
216
913
194
792
2.88
33.35
9.0
3.5
5.92
5.82
kpa
0.66
187
775
188
762
2.89
32.70
9.3
3.5
1.44
1.97
mmol/l
1.22
166
660
551
3695
2.41
32.04
19.5
7.4
1.21
1.21
mmol/l
0.13
490
3192
598
4278
2.36
28.14
10.4
5.3
7.85
6.68
mmol/l
16.80
576
4073
469
3131
2.12
24.90
4.0
2.4
74.70
77.45
nmol/l
1.49
429
2811
506
3511
2.10
23.81
19.0
16.2
1.28
1.29
inr
0.10
430
2956
153
655
2.63
23.36
15.5
9.5
—
—
—
0
0
40
67
6.22
23.13
1.1
1.2
—
—
—
0
0
352
2189
2.04
21.76
5.5
4.4
—
—
—
0
0
57
139
4.33
21.58
2.0
1.4
—
—
—
0
0
468
3262
1.98
20.49
10.7
5.1
34.88
35.37
g/l
1.00
442
3058
473
3310
1.98
20.46
15.9
6.8
1.21
1.21
mmol/l
0.19
440
3059
42
83
5.27
20.43
2.7
2.7
2.13
0.81
g/24h
2.82
30
48
475
3351
1.95
19.82
8.0
6.3
2.67
2.87
%
1.28
443
3152
480
3414
1.94
19.37
8.1
6.4
24.25
26.92
%
5.84
453
3252
121
504
2.64
19.34
5.1
3.7
7.40
7.42
ph
2.93
108
424
350
2242
1.96
19.30
4.3
3.3
—
—
—
0
0
473
3354
1.93
19.20
8.1
6.4
0.63
0.67
%
0.84
443
3152
148
682
2.42
19.11
5.6
2.8
5.04
4.47
kpa
2.12
143
667
473
3361
1.93
19.00
8.2
6.4
9.11
8.94
%
0.52
441
3164
60
169
3.75
18.66
2.8
2.4
252.75
85.04
ug/min
1.29
43
101
669
5400
2.15
18.10
12.3
8.4
87.68
79.21
u/l
2.57
639
5113
470
3370
1.89
17.97
7.9
6.2
60.64
57.88
%
5.15
445
3216
368
2440
1.90
17.94
6.7
3.4
18.72
88.87
e6/l
1.90
305
1893
50
130
4.03
17.39
2.1
1.4
136.81
173.68
au/ml
1.21
16
33
361
2402
1.88
17.22
7.9
6.1
—
—
—
0
0
303
1906
1.92
17.18
4.5
2.7
376.80
352.39
umol/l
3.05
263
1686
354
2348
1.87
17.00
3.8
3.3
2375.47
1579.31
ng/l
1.62
307
2017
116
503
2.51
16.99
6.3
3.0
120.42
128.74
g/l
3.06
110
493
277
1699
1.94
16.88
5.3
2.7
4.27
5.21
e6/l
1.03
259
1553
348
2300
1.87
16.86
2.7
2.2
307.94
281.57
u/l
0.11
332
2186
497
3674
1.86
16.78
8.0
6.3
1.82
1.86
e9/l
0.14
435
3232
198
1083
2.08
16.66
3.4
2.1
—
—
—
0
0
504
3753
1.85
16.50
8.1
6.5
0.20
0.20
e9/l
0.25
438
3279
211
1188
2.03
16.38
2.7
2.0
29.39
29.52
s
0.10
206
1157
93
371
2.69
16.12
8.1
3.1
24.57
25.37
mmol/l
1.04
88
363
285
1790
1.89
16.01
3.2
2.5
—
—
—
0
0
241
1432
1.96
16.00
5.2
4.3
467.42
379.45
ng/l
0.23
205
1165
488
3628
1.82
15.75
8.0
6.2
0.04
0.04
e9/l
0.45
419
3115
49
136
3.76
15.56
1.6
1.2
328.93
268.74
u/ml
0.57
27
77
26
42
6.36
15.54
3.5
1.7
152.69
91.73
ng/l
1.22
26
42
138
672
2.26
15.51
9.3
4.5
7.35
7.35
ph
0.03
102
499
140
686
2.25
15.50
3.5
2.8
69.82
68.94
e9/l
0.10
107
517
210
1202
1.99
15.46
4.9
3.2
2.44
1.92
e6/l
0.44
124
613
586
4627
1.87
15.33
7.1
4.9
8375.67
2133.13
e6/l
0.37
12
77
452
3305
1.79
15.21
2.7
2.2
95.88
95.52
pmol/l
0.05
236
1776
331
2211
1.82
15.08
11.0
4.3
7.39
7.40
ph
0.51
265
1611
484
3617
1.79
15.07
8.0
6.2
0.64
0.60
e9/l
3.18
414
3103
91
372
2.62
15.01
2.1
2.1
1.53
1.52
g/l
0.05
82
336
168
896
2.09
14.98
3.7
2.7
1.80
1.79
%
0.04
152
819
390
2742
1.79
14.91
7.7
4.0
108.09
102.56
e6/l
0.06
312
1983
298
1934
1.84
14.87
3.2
2.2
2.97
2.96
mg/l
0.02
261
1660
441
3219
1.77
14.77
5.7
3.1
157.21
141.60
ug/l
0.50
416
3000
217
1277
1.94
14.65
3.9
3.4
0.82
0.82
mmol/l
0.08
200
1214
315
2093
1.81
14.46
5.8
3.3
0.34
0.43
e6/l
0.33
256
1555
34
76
4.62
14.35
3.5
1.8
11.15
10.36
%
0.52
34
76
46
130
3.68
14.24
10.8
1.4
1.03
0.92
nmol/l
0.31
40
109
87
359
2.59
14.06
4.8
3.9
—
—
—
0
0
131
653
2.19
13.83
2.5
2.4
5.48
7.34
ug/l
1.12
116
575
129
640
2.20
13.78
2.3
3.1
66.33
66.40
g/l
0.04
115
593
344
2385
1.75
13.40
3.4
2.5
—
—
—
0
0
30
64
4.82
13.38
1.7
3.0
1871.33
929.80
mg
1.13
30
64
238
1483
1.84
13.29
5.1
3.0
481.15
538.15
mosm/kgh2o
4.82
217
1299
70
269
2.75
13.01
1.2
1.3
—
—
—
0
0
110
523
2.27
13.00
1.9
2.8
—
—
—
0
0
498
3854
1.71
12.77
6.9
6.7
11.33
11.83
umol/l
0.41
469
3695
213
1300
1.85
12.63
4.7
3.0
1.07
1.00
e6/l
0.08
132
707
96
440
2.33
12.35
14.3
10.9
15.43
15.75
%
0.49
89
427
164
926
1.96
12.30
11.9
8.3
7.40
7.41
ph
1.06
81
537
733
6418
2.08
11.82
12.1
6.4
46.38
39.29
mmol/mol
33.39
685
5998
68
277
2.58
11.27
5.0
4.3
23.87
25.11
mmol/l
2.94
63
259
161
931
1.90
11.17
12.0
8.2
5.05
5.12
kpa
0.33
149
900
161
932
1.90
11.13
12.0
8.2
12.73
11.92
kpa
0.84
150
903
436
3330
1.64
11.12
3.7
2.9
—
—
estimate
—
0
0
67
273
2.58
11.10
2.3
3.9
41.13
42.09
mg/l
0.03
59
231
512
4075
1.65
11.05
9.9
9.7
4.49
4.21
e9/l
1.74
442
3561
147
828
1.94
11.02
12.2
8.5
95.46
95.23
%
0.19
138
807
67
274
2.57
11.02
2.3
3.9
52.24
74.57
mg/l
0.48
59
233
162
944
1.89
10.96
1.5
1.4
698.29
487.22
titre
0.47
35
205
20
19
10.75
10.81
6.9
4.6
—
—
—
0
0
267
1816
1.69
10.61
6.2
4.2
89.94
87.61
%
0.72
260
1785
157
918
1.87
10.48
11.9
8.3
0.45
1.05
mmol/l
1.07
129
752
54
205
2.75
10.29
1.4
1.2
—
—
—
0
0
80
367
2.30
10.25
6.9
4.7
1.36
1.55
%
1.75
72
351
135
758
1.93
10.18
2.8
1.6
—
—
—
0
0
204
1309
1.74
9.94
1.7
1.7
1154.62
1173.46
nmol/l
0.09
153
995
108
568
2.03
9.80
3.0
2.8
11.02
10.64
g/l
0.36
98
521
395
3007
1.59
9.77
5.3
3.5
6.22
6.24
ph
0.13
238
1716
768
6945
2.18
9.77
39.7
20.6
4.04
3.99
mmol/l
6.40
757
6799
32
92
3.58
9.70
1.1
1.1
43.85
80.95
iu/ml
—
6
21
134
764
1.90
9.62
13.6
9.0
114.29
120.68
g/l
2.61
127
752
64
274
2.45
9.57
1.9
2.9
9.98
10.31
g/l
0.23
57
249
767
6943
2.15
9.56
38.8
20.4
139.22
139.64
mmol/l
4.32
757
6809
91
453
2.13
9.55
2.1
1.8
1.11
1.49
g/l
1.14
81
417
29
79
3.77
9.50
1.1
1.2
—
—
—
0
0
753
6777
2.03
9.43
31.7
17.2
26.66
25.61
mg/l
0.40
668
5661
46
168
2.84
9.43
3.0
2.3
120.94
128.26
g/l
1.23
36
130
73
334
2.30
9.41
7.1
4.9
0.82
0.85
%
0.25
65
318
61
259
2.46
9.29
2.2
2.1
21.57
20.72
s
0.50
61
238
374
2836
1.57
9.25
2.4
1.9
1.38
1.33
mmol/l
0.57
324
2397
16
14
11.62
9.09
1.1
1.0
—
—
—
0
0
14
9
15.78
9.05
12.7
13.4
5.06
5.43
mmol/l
—
14
9
340
2534
1.57
9.00
4.8
3.7
—
0.70
—
0
10
151
918
1.79
8.79
2.7
1.6
—
—
—
0
0
58
250
2.42
8.56
2.3
3.8
1.35
2.75
ratio
2.34
35
147
120
685
1.88
8.55
2.1
2.0
387.12
385.25
nmol/l
0.03
110
636
16
16
10.17
8.55
1.0
1.0
—
—
—
0
0
467
3763
1.54
8.55
6.4
4.0
0.03
1.99
estimate
0.49
97
817
123
708
1.86
8.54
3.4
2.3
0.21
0.21
g/l
0.09
116
658
298
2192
1.56
8.17
2.1
1.7
18.90
19.82
nmol/l
0.56
255
1869
466
3775
1.52
8.16
6.6
4.0
0.14
0.40
estimate
0.28
76
767
59
263
2.34
8.09
5.6
3.4
479.31
277.45
mg/l
1.43
36
110
310
2313
1.54
7.91
5.9
2.6
58.42
64.31
u/l
0.75
287
2158
458
3714
1.51
7.86
6.3
3.9
0.00
0.00
estimate
0.50
93
799
110
627
1.87
7.86
4.2
3.3
374.56
231.79
ng/l
1.30
100
585
227
1583
1.59
7.78
1.9
1.7
1.13
1.32
mg/l
0.84
189
1243
222
1556
1.58
7.40
1.4
1.3
2.77
1.25
u/ml
0.88
60
429
318
2425
1.50
7.16
4.2
3.3
43.92
34.39
u/l
0.51
306
2297
200
1379
1.59
7.12
1.8
1.5
2.77
2.52
g/l
0.85
123
846
698
6266
1.66
7.11
6.7
5.1
1.94
1.94
mu/l
0.01
637
5777
14
16
8.88
7.06
1.0
1.0
—
—
—
0
0
25
76
3.36
7.01
1.4
2.7
—
—
—
0
0
167
1110
1.63
6.90
2.9
1.8
—
—
—
0
0
88
489
1.89
6.80
1.6
1.5
—
—
—
0
0
369
2923
1.47
6.76
5.3
4.0
190.47
87.96
ng/l
0.32
301
2120
50
226
2.29
6.67
7.7
6.3
1.56
1.38
mmol/l
0.48
44
200
39
158
2.54
6.60
4.7
2.7
89.78
89.85
%
0.01
39
152
769
7131
1.88
6.47
18.8
12.1
26.77
26.53
u/l
0.12
747
6921
37
148
2.57
6.43
1.6
1.2
—
—
—
0
0
68
354
2.00
6.35
2.1
1.8
2.72
1.42
ug/l
0.60
56
315
596
5224
1.48
6.15
5.0
4.2
14.85
14.88
pmol/l
0.09
543
4795
773
7199
1.88
6.13
40.2
22.3
104.25
80.19
umol/l
11.78
764
7107
149
990
1.61
6.12
1.3
1.2
—
—
—
0
0
277
2109
1.47
6.07
7.8
6.4
—
—
—
0
0
57
286
2.06
5.90
1.9
2.0
8.23
9.20
iu/ml
0.08
18
75
738
6804
1.67
5.79
8.1
5.8
2.37
2.66
mmol/l
15.65
695
6308
108
671
1.70
5.75
4.1
4.4
1.06
0.90
%
0.15
44
215
728
6692
1.64
5.74
7.2
5.1
4.25
4.56
mmol/l
14.24
692
6234
133
877
1.61
5.62
3.7
3.2
4.99
5.61
e9/l
0.36
111
770
102
630
1.70
5.55
4.3
4.5
0.05
0.14
%
1.05
38
175
45
212
2.19
5.48
1.7
1.4
283.33
288.24
ug/g
0.06
33
126
722
6652
1.59
5.31
7.3
5.0
1.37
1.44
mmol/l
4.82
682
6161
382
3141
1.39
5.28
16.9
11.6
0.00
0.00
e9/l
1.09
300
2576
780
7345
1.82
5.09
45.0
25.7
90.93
91.30
fl
1.48
772
7262
780
7346
1.82
5.08
45.2
25.7
248.39
245.81
e9/l
0.51
769
7204
780
7348
1.81
5.04
46.8
26.2
38.94
40.29
%
7.70
772
7260
780
7348
1.81
5.04
45.0
25.6
30.12
30.39
pg
4.37
772
7264
780
7348
1.81
5.04
45.1
25.7
4.38
4.48
e12/l
5.36
769
7186
780
7349
1.81
5.03
45.1
25.8
7.17
6.79
e9/l
3.10
768
7186
780
7349
1.81
5.03
45.4
25.9
130.49
135.08
g/l
11.41
772
7267
39
180
2.22
5.01
2.8
2.9
32.43
33.61
umol/l
0.11
33
160
100
633
1.66
4.96
4.1
4.3
0.94
0.55
%
0.47
42
196
694
6366
1.51
4.91
6.1
4.3
1.37
1.29
mmol/l
2.46
646
5865
105
676
1.63
4.88
4.8
2.4
44.24
35.91
u/l
0.53
83
576
19
62
3.11
4.81
2.3
2.4
—
—
—
0
0
63
353
1.85
4.78
2.6
2.4
—
—
—
0
0
13
25
5.26
4.78
3.6
2.4
0.67
0.59
mmol/l
1.66
13
25
100
643
1.63
4.67
4.5
4.7
0.03
0.16
%
1.15
36
164
87
543
1.67
4.56
1.2
1.2
—
—
—
0
0
22
81
2.76
4.54
1.5
1.6
59.40
63.93
%
0.19
15
57
39
188
2.13
4.53
3.0
2.5
12.81
12.15
mg/l
0.18
33
172
249
1946
1.40
4.50
1.4
1.4
—
—
—
0
0
124
851
1.54
4.39
3.3
2.7
7.25
8.89
umol/l
0.60
108
758
331
2722
1.36
4.33
2.4
2.2
—
—
—
0
0
14
34
4.17
4.22
2.6
3.8
534.79
1067.29
u/ml
0.77
14
34
37
180
2.10
4.21
1.5
1.7
—
—
—
0
0
17
57
3.02
4.14
2.9
2.7
9.28
8.38
mmol/l
0.46
17
57
27
116
2.37
4.12
1.9
1.8
0.60
0.82
g/l
0.50
19
93
127
892
1.50
4.04
2.0
1.4
—
—
—
0
0
62
371
1.72
3.82
3.3
3.5
4.26
4.47
pmol/l
0.65
52
331
117
818
1.50
3.80
1.4
1.4
—
—
—
0
0
54
311
1.79
3.79
2.6
2.1
—
—
—
0
0
34
168
2.07
3.74
5.0
3.8
—
—
—
0
0
254
2044
1.35
3.72
6.1
3.5
0.57
0.06
estimate
0.71
72
631
59
353
1.72
3.65
2.8
2.2
0.00
2.39
estimate
0.50
13
105
85
559
1.58
3.65
4.9
2.8
5.97
6.09
ph
0.51
68
379
79
514
1.59
3.55
17.0
10.4
1.17
1.30
%
1.01
79
509
33
165
2.04
3.54
2.0
1.8
6.30
5.04
iu/l
0.15
15
57
26
120
2.20
3.41
1.2
1.5
30.73
30.43
g/l
0.04
21
107
70
447
1.62
3.40
2.6
2.6
54.98
22.71
au/ml
—
5
38
97
669
1.51
3.37
2.9
2.1
0.00
0.02
estimate
0.50
21
137
78
514
1.57
3.33
17.2
10.6
93.86
93.89
%
0.01
78
509
61
380
1.65
3.27
1.2
1.2
—
—
—
0
0
89
607
1.52
3.26
1.6
1.4
—
—
—
0
0
300
2515
1.30
3.21
5.0
3.4
2.35
2.35
mmol/l
0.09
277
2270
36
193
1.90
3.20
1.9
1.2
1.67
10.07
u/ml
—
6
34
8
15
5.37
3.19
1.3
1.1
—
—
—
0
0
8
15
5.37
3.19
6.8
8.3
5.71
5.35
kpa
—
8
15
7
11
6.41
3.19
1.3
1.7
—
—
—
0
0
31
158
2.00
3.18
10.1
6.9
104.04
105.33
mmol/l
0.48
23
147
31
158
2.00
3.18
10.1
6.9
12.96
11.29
mmol/l
1.41
23
147
516
4641
1.29
3.16
4.7
3.3
61.00
50.28
u/l
1.64
476
4378
333
2839
1.29
3.11
6.5
3.9
0.01
0.04
estimate
0.78
78
667
35
192
1.86
2.92
1.6
1.2
1.26
2.62
u/ml
—
5
23
11
32
3.47
2.90
1.5
1.5
40.09
55.69
ug/l
0.90
11
32
7
13
5.42
2.87
1.4
1.3
—
—
—
0
0
8
18
4.48
2.80
1.0
1.4
29.88
26.78
s
—
8
18
35
195
1.83
2.80
5.7
4.6
—
—
—
0
0
15
59
2.57
2.80
1.1
1.1
—
—
—
0
0
18
79
2.31
2.69
1.6
1.2
—
—
nmol/l
—
0
0
20
92
2.20
2.69
1.2
1.3
2.13
6.85
u/ml
1.19
15
41
193
1561
1.31
2.64
1.8
1.7
446.14
25364420.08
pmol/l
1.24
164
1305
732
6966
1.38
2.62
27.5
15.4
—
—
—
0
0
14
55
2.57
2.62
2.0
1.2
110.71
101.87
pmol/l
0.23
14
55
46
287
1.64
2.51
1.4
1.2
1.38
1.48
u/ml
—
6
21
18
82
2.22
2.49
2.1
2.2
—
—
—
0
0
72
500
1.48
2.47
10.9
6.6
23.40
24.45
mmol/l
1.64
64
482
112
844
1.38
2.46
3.0
2.5
228.18
131.59
ug/g
1.10
93
684
14
57
2.48
2.46
2.7
2.8
14.44
16.28
%
1.25
14
57
21
103
2.07
2.43
1.2
1.3
1557.36
1637.32
e6/l
0.05
11
69
5
8
6.28
2.37
1.2
1.4
—
—
—
0
0
81
582
1.43
2.34
8.2
4.1
1.23
1.23
mmol/l
0.02
73
508
70
489
1.47
2.34
2.7
1.7
—
—
—
0
0
693
6568
1.31
2.34
6.7
5.2
6.89
5.97
mmol/l
18.01
626
6023
15
65
2.33
2.32
1.5
1.2
2.54
2.87
g/l
—
9
48
15
65
2.33
2.32
1.5
1.2
6.35
6.50
g/l
—
9
48
15
65
2.33
2.32
1.5
1.2
0.36
0.41
g/l
—
9
47
6
13
4.64
2.27
1.5
1.2
91.00
67.38
nmol/24h
—
6
13
17
79
2.18
2.26
1.8
4.2
—
—
—
0
0
15
66
2.30
2.25
1.5
1.2
—
—
—
0
0
20
100
2.02
2.22
1.0
1.1
1.60
0.90
u/ml
—
9
41
20
100
2.02
2.22
1.1
1.1
5.34
5.78
u/ml
0.03
12
54
16
73
2.21
2.22
4.9
2.4
—
—
—
0
0
21
107
1.99
2.22
2.9
2.5
4.10
4.08
mmol/l
0.06
21
107
21
107
1.99
2.22
2.9
2.5
104.71
105.27
mmol/l
0.20
21
107
6
14
4.31
2.15
1.2
1.6
—
—
—
0
0
10
36
2.80
2.14
1.9
3.7
78.10
169.47
nmol/l
—
10
36
18
88
2.07
2.12
1.3
1.3
59016.00
36102.53
e6/l
—
6
49
29
475
0.60
2.03
1.3
1.8
3.01
3.47
mmol/l
1.07
18
349
8
26
3.10
2.01
1.1
1.1
—
—
—
0
0
24
134
1.81
1.97
1.4
1.3
—
—
—
0
0
11
45
2.46
1.93
1.7
1.8
41.90
37.18
%
0.50
11
45
16
78
2.07
1.92
1.3
1.2
—
—
—
0
0
33
204
1.64
1.92
1.4
1.6
15129.92
13923.53
e6/l
0.08
25
146
19
99
1.94
1.91
2.1
1.6
—
—
—
0
0
20
107
1.89
1.87
3.0
2.5
1.18
1.19
mmol/l
0.61
20
107
8
28
2.87
1.86
9.8
3.3
—
—
—
0
0
8
28
2.87
1.86
1.3
1.1
—
—
—
0
0
8
28
2.87
1.86
1.3
1.1
—
—
—
0
0
8
28
2.87
1.86
1.3
1.1
—
—
—
0
0
17
86
2.00
1.86
1.2
1.3
—
—
—
0
0
19
101
1.90
1.82
1.5
1.5
—
—
—
0
0
19
101
1.90
1.82
1.5
1.5
—
—
—
0
0
19
101
1.90
1.82
1.5
1.5
—
—
—
0
0
19
101
1.90
1.82
1.5
1.5
—
—
—
0
0
12
53
2.28
1.81
1.2
1.1
—
—
—
0
0
8
29
2.77
1.79
9.8
3.2
—
—
—
0
0
8
30
2.68
1.72
1.0
1.1
139.62
184.19
mmol/24h
—
8
30
14
68
2.08
1.71
2.1
1.3
21.87
30.09
ng/l
0.66
14
68
17
89
1.93
1.71
1.2
1.6
—
—
—
0
0
13
62
2.11
1.66
1.4
1.2
—
—
—
0
0
34
221
1.56
1.64
1.3
1.1
—
—
—
0
0
243
2127
1.20
1.60
6.3
3.9
0.00
0.01
estimate
1.15
80
739
8
32
2.51
1.60
1.3
1.9
38.65
40.05
g/l
—
8
32
10
44
2.29
1.56
1.0
1.1
295.10
225.13
mg/l
—
10
39
6
21
2.87
1.50
1.2
1.6
—
—
—
0
0
5
16
3.14
1.44
1.8
1.9
—
—
—
0
0
19
110
1.74
1.44
1.2
1.1
—
—
—
0
0
6
22
2.74
1.43
3.3
2.8
3.17
6.50
ug/l
—
6
22
10
46
2.19
1.40
1.1
1.1
54.85
39.38
mg/l
—
10
38
9
41
2.21
1.37
1.3
2.0
—
—
—
0
0
63
480
1.34
1.36
7.8
4.7
—
—
—
0
0
29
191
1.54
1.36
1.6
1.3
7.72
8.75
u/l
0.18
23
151
59
449
1.34
1.30
1.4
1.3
312.63
219.80
u/ml
0.24
54
415
298
2697
1.16
1.29
4.7
5.6
7.67
2.39
ug/l
0.71
269
2420
193
1687
1.19
1.28
7.0
4.1
1.02
1.02
kg/l
0.50
159
1119
18
108
1.68
1.23
1.1
1.1
—
—
—
0
0
5
19
2.64
1.21
2.0
1.4
33.40
32.95
%
—
5
19
182
1593
1.18
1.19
5.4
4.8
—
—
—
0
0
6
26
2.32
1.19
1.5
1.4
—
—
—
0
0
8
38
2.12
1.18
1.1
1.1
1837.00
1551.61
miu/ml
—
8
38
138
1182
1.20
1.15
1.3
1.3
10.54
12.87
u/ml
0.18
45
452
5
20
2.51
1.15
1.4
1.7
—
—
—
0
0
7
30
2.34
1.12
1.7
1.4
—
1.50
—
0
6
11
58
1.91
1.12
1.6
1.4
41.60
32.05
%
—
5
38
19
119
1.61
1.12
1.0
1.2
0.33
1.99
u/ml
—
10
63
236
2609
0.87
1.08
4.3
3.2
—
—
—
0
0
16
99
1.63
1.00
1.0
1.1
0.19
1.82
u/ml
—
8
48
43
559
0.76
1.00
1.4
1.4
—
—
—
0
0
15
93
1.62
0.94
1.3
1.4
—
—
—
0
0
145
1272
1.17
0.94
1.4
1.3
24.98
34.43
iu/ml
1.01
46
386
11
63
1.76
0.90
1.5
1.2
—
—
—
0
0
6
29
2.08
0.89
2.2
3.7
25.17
30.50
umol/l
—
6
21
12
71
1.70
0.89
1.3
1.2
—
—
—
0
0
10
56
1.80
0.88
1.5
1.5
88.10
79.70
umol/l
—
10
56
8
45
1.79
0.84
1.3
1.5
125.53
161.40
pmol/l
—
8
45
11
178
0.61
0.83
1.1
1.2
—
—
—
0
0
8
47
1.71
0.81
1.4
1.7
—
—
—
0
0
46
572
0.79
0.79
6.4
3.7
—
—
—
0
0
0
26
0.00
0.78
0.0
1.2
—
52.59
—
0
8
92
792
1.18
0.77
3.2
4.4
108.26
20.18
ug/l
0.40
73
671
164
1477
1.14
0.76
3.5
3.0
2.47
2.45
mmol/l
1.14
143
1324
14
91
1.55
0.75
1.1
1.1
1.36
1.78
u/ml
—
6
42
30
228
1.33
0.73
1.1
1.1
—
—
—
0
0
14
92
1.53
0.72
1.4
1.3
—
—
—
0
0
13
84
1.56
0.72
1.0
1.1
1.22
3.68
u/ml
—
5
34
26
194
1.35
0.72
5.8
3.3
7.71
1.94
index
0.42
14
106
39
309
1.27
0.72
1.3
1.2
—
—
—
0
0
10
158
0.63
0.71
1.1
1.8
—
—
—
0
0
40
319
1.27
0.70
2.5
2.9
—
—
—
0
0
16
226
0.70
0.67
1.5
1.5
—
—
—
0
0
10
62
1.62
0.65
1.6
1.3
—
—
—
0
0
7
44
1.60
0.65
8.0
3.4
0.29
0.93
index
—
7
44
7
44
1.60
0.65
1.0
1.1
—
5.87
—
0
16
29
226
1.29
0.62
1.9
1.6
9.43
10.32
u/ml
—
6
51
8
51
1.57
0.60
1.3
1.1
—
—
—
0
0
52
438
1.20
0.58
1.3
1.2
244.05
131.05
u/ml
0.57
14
170
21
159
1.33
0.55
1.8
2.0
1902.30
2857.60
u/l
—
7
57
17
228
0.74
0.55
1.5
1.5
—
—
—
0
0
17
227
0.74
0.54
1.5
1.5
—
—
—
0
0
17
226
0.75
0.52
1.5
1.5
—
—
—
0
0
10
66
1.52
0.52
1.4
1.2
—
—
—
0
0
17
127
1.35
0.50
2.9
3.6
3.87
4.18
e9/l
0.42
17
127
12
84
1.43
0.49
1.1
1.2
—
—
—
0
0
7
45
1.56
0.49
1.3
1.2
—
—
—
0
0
24
191
1.26
0.47
1.0
1.2
—
—
—
0
0
33
273
1.22
0.46
1.6
1.4
22.00
26.94
iu/l
0.31
28
230
16
209
0.76
0.45
1.5
1.5
—
—
—
0
0
79
708
1.13
0.43
1.7
1.5
—
—
—
0
0
24
294
0.81
0.42
1.7
1.6
—
—
—
0
0
0
17
0.00
0.40
0.0
2.2
—
17.55
—
0
17
11
147
0.74
0.37
2.1
1.6
—
—
—
0
0
9
69
1.31
0.37
2.7
2.3
—
—
—
0
0
41
359
1.15
0.34
6.5
4.6
36.94
36.91
°c
0.20
41
354
6
88
0.68
0.33
1.0
1.1
—
—
—
0
0
18
146
1.24
0.32
6.4
4.2
19.60
29.58
mg/l
1.34
12
107
52
465
1.13
0.32
1.3
1.3
—
—
—
0
0
12
154
0.78
0.32
1.4
1.3
—
—
—
0
0
15
120
1.25
0.30
2.1
2.3
—
—
—
0
0
19
157
1.22
0.29
2.7
3.4
57.35
58.70
%
0.28
19
157
14
173
0.81
0.28
1.6
1.5
—
—
—
0
0
15
122
1.23
0.27
1.3
1.7
—
—
—
0
0
19
225
0.84
0.26
13.6
10.4
—
—
—
0
0
11
88
1.25
0.22
1.3
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
22.60
—
0
5
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
65
607
1.08
0.20
1.4
1.4
—
—
—
0
0
12
99
1.22
0.19
1.4
2.0
30.50
32.54
pg
0.75
12
99
11
90
1.23
0.19
1.4
1.1
—
—
—
0
0
154
1597
0.96
0.18
3.1
3.3
0.82
0.77
ug/l
0.33
101
1047
8
68
1.18
0.16
1.1
1.2
—
—
—
0
0
8
69
1.16
0.16
1.5
1.4
—
—
—
0
0
101
967
1.05
0.16
1.3
1.3
—
—
—
0
0
6
77
0.78
0.15
1.5
1.5
—
—
—
0
0
6
80
0.75
0.15
1.7
1.6
—
—
—
0
0
9
80
1.13
0.15
1.3
1.8
—
—
—
0
0
22
199
1.11
0.13
1.0
1.1
—
—
—
0
0
23
252
0.91
0.13
1.7
1.9
38.48
39.93
nmol/l
0.14
23
242
10
115
0.87
0.10
1.2
1.1
—
—
—
0
0
10
115
0.87
0.10
1.2
1.1
—
—
—
0
0
34
319
1.07
0.10
1.0
1.1
—
—
—
0
0
17
154
1.11
0.10
3.6
4.5
2.20
2.65
mmol/l
0.44
12
105
10
87
1.15
0.09
1.1
1.3
—
—
—
0
0
7
64
1.09
0.08
1.3
1.2
—
—
—
0
0
9
104
0.86
0.06
1.3
1.7
—
—
—
0
0
66
677
0.97
0.05
2.5
2.4
12.77
13.41
nmol/l
0.24
59
626
32
308
1.04
0.04
2.0
1.7
0.34
0.33
mg/l
0.03
17
145
13
121
1.08
0.03
2.7
2.7
—
—
—
0
0
71
721
0.98
0.02
1.4
1.6
—
—
—
0
0
24
232
1.04
0.02
1.2
1.2
0.85
0.91
g/l
0.70
24
232
10
98
1.02
0.00
1.1
1.2
—
—
—
0
0
22
221
1.00
0.00
1.0
1.1
1.45
1.52
g/l
0.74
22
221
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
5
59
0.85
-0.00
1.6
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
59
0.85
-0.00
1.4
1.7
0.68
1.19
promille
—
5
48
0
5
0.00
-0.00
0.0
4.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.8
—
9.00
—
0
5
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H7_BCKRNDRETINOPAT and mortality.

Females

Parameter HR [95% CI] p-value
H7_BCKRNDRETINOPAT 1.398 [1.23, 1.59] < 0.001
Birth year 0.998 [0.99, 1.01] 0.678

During the follow-up period (1.1.1998 — 31.12.2019), 810 out of 2446 females with H7_BCKRNDRETINOPAT died.

Males

Parameter HR [95% CI] p-value
H7_BCKRNDRETINOPAT 1.353 [1.17, 1.56] < 0.001
Birth year 0.99 [0.98, 1.0] 0.037

During the follow-up period (1.1.1998 — 31.12.2019), 716 out of 2418 males with H7_BCKRNDRETINOPAT died.

Mortality risk

Mortality risk for people of age

years, who have H7_BCKRNDRETINOPAT.

N-year risk Females Males
1 0.149% 0.271%
5 0.836% 1.616%
10 2.152% 4.152%
15 4.438% 7.965%
20 7.889% 13.748%

Relationships between endpoints

Index endpoint: H7_BCKRNDRETINOPAT – Background retinopathy and retinal vascular changes

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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