muscular disease: Acquired, familial, and congenital disorders of skeletal muscle and smooth muscle.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
282 |
4. Check minimum number of eventsNone |
282 |
5. Include endpointsNone |
282 |
6. Filter based on genotype QC (FinnGen only) |
254 |
Control definitions (FinnGen only)
- Control exclude
- M13_SOFTTISSUE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M62
- Name in latin
- Ruptura musculi non traumatica
Similar endpoints
↥List of similar endpoints to
Other rupture of muscle
based on the number of shared cases.
Similar with more cases:
- Disorders of muscles
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any operation in hilmo
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1604 | 713 | 883 |
| Only index persons | 1502 | 672 | 830 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.02 |
| Only index persons | 0.03 | 0.02 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 53.09 | 53.57 | 52.63 |
| Only index persons | 52.22 | 52.43 | 52.04 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 254 | 140 | 114 |
| Unadjusted period prevalence (%) | 0.05 | 0.05 | 0.05 |
| Median age at first event (years) | 54.28 | 52.02 | 57.04 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 269
- Matched controls
- 2690
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M62.1
ICD-10 Finland
Other rupture of muscle (nontraumatic)
+∞
307.7
269
*
M75.1
ICD-10 Finland
Rotator cuff syndrome
4.6
27.4
83
237
M79.6
ICD-10 Finland
Pain in limb
3.8
25.5
135
569
K42.9
ICD-10 Finland
Umbilical hernia without obstruction or gangrene
6.0
18.8
36
68
QBJ30
NOMESCO Finland
Correction of abdominal apron
56.7
18.2
21
*
X59
ICD-10 Finland
Exposure to unspecified factor
3.2
13.4
65
246
M25.5
ICD-10 Finland
Pain in joint
2.7
13.3
98
465
N02AJ06
ATC
codeine and paracetamol; systemic
2.6
13.1
132
731
JAG96
NOMESCO Finland
Other reconstruction of abdominal wall
136.1
12.5
13
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.7
12.5
43
130
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.5
11.7
131
750
M62.0
ICD-10 Finland
Diastasis of muscle
68.0
11.7
13
*
N02BF01
ATC
gabapentin; oral
4.1
11.2
33
89
N02AX02
ATC
tramadol; systemic, rectal
2.4
11.1
123
697
M76.6
ICD-10 Finland
Achilles tendinitis
5.9
10.9
20
36
M75.3
ICD-10 Finland
Calcific tendinitis of shoulder
62.5
10.7
12
*
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
5.1
10.7
23
48
N39.4
ICD-10 Finland
Other specified urinary incontinence
4.1
10.7
31
83
N03AX12
ATC
[U] gabapentin; oral
3.2
10.6
48
173
N02BE01
ATC
paracetamol; systemic, rectal
4.4
10.4
250
2014
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
12.0
10.2
18
16
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.8
9.8
32
93
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.3
9.8
104
573
UJF32
NOMESCO Finland
Coloscopy
2.5
9.7
79
386
M79.1
ICD-10 Finland
Myalgia
3.1
9.6
45
165
M70.6
ICD-10 Finland
Trochanteric bursitis
3.5
9.6
36
115
Z01.8
ICD-10 Finland
Other specified special examinations
2.6
9.6
68
311
UKC02
NOMESCO Finland
Cystoscopy
2.8
9.5
54
220
M54.5
ICD-10 Finland
Low back pain
2.3
9.3
100
552
X58
ICD-10 Finland
Exposure to other specified factors
2.9
9.2
49
193
J01DB01
ATC
cefalexin; oral
2.8
9.0
228
1786
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
3.9
8.8
27
75
M17.1
ICD-10 Finland
Other primary gonarthrosis
2.6
8.8
59
262
N03AX16
ATC
[U] pregabalin
2.5
8.8
63
289
S18
ICPC
Laceration/cut
2.2
8.7
132
830
SPAT1263
SPAT
Sampling
2.2
8.7
117
702
M19.0
ICD-10 Finland
Primary arthrosis of other joints
3.8
8.6
27
76
G44.2
ICD-10 Finland
Tension-type headache
3.0
8.6
42
157
L14
ICPC
Leg/thigh symptom/complaint
3.7
8.6
28
81
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
15.1
8.3
13
9
W10
ICD-10 Finland
Fall on and from stairs and steps
4.0
8.3
24
64
M01AH05
ATC
etoricoxib; oral
2.1
8.2
170
1197
R06.0
ICD-10 Finland
Dyspnoea
2.3
8.1
76
393
B01AB05
ATC
enoxaparin; parenteral
2.2
8.0
90
501
M02AA07
ATC
piroxicam; topical
2.2
7.9
95
542
L17
ICPC
Foot/toe symptom/complaint
2.2
7.9
82
442
SPAT1249
SPAT
Treatment-related counselling outside office
2.1
7.8
108
650
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
4.2
7.8
21
53
H02AB06
ATC
prednisolone; systemic
2.1
7.7
130
842
L03
ICPC
Low back symptom/complaint
2.2
7.6
76
401
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.9
7.5
38
145
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
82.3
7.5
8
*
L08
ICPC
Shoulder symptom/complaint
2.4
7.3
60
292
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.0
7.2
111
691
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
2.0
7.1
149
1031
S76.3
ICD-10 Finland
Injury of muscle and tendon of the posterior muscle group at thigh level
10.4
7.1
13
13
M54.4
ICD-10 Finland
Lumbago with sciatica
2.5
7.0
50
228
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
8.6
6.9
14
17
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
3.8
6.9
21
58
M79.0
ICD-10 Finland
Rheumatism, unspecified
41.1
6.8
8
*
L13
ICPC
Hip symptom/complaint
2.4
6.8
50
231
Z50.1
ICD-10 Finland
Other physical therapy
3.8
6.6
20
55
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.1
6.6
82
470
R52.9
ICD-10 Finland
Pain, unspecified
2.8
6.4
33
127
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.5
6.2
40
173
NFL30
NOMESCO Finland
Transposition of muscle of hip or thigh
12.9
6.1
10
8
M72.2
ICD-10 Finland
Plantar fascial fibromatosis
3.3
6.0
23
74
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
115
649
2.35
10.33
3.3
2.4
52.94
71.07
u/l
1.18
104
605
207
1581
2.34
8.04
4.6
3.7
10.65
11.41
mm/h
0.40
194
1485
118
728
2.11
8.04
3.4
3.0
—
—
—
0
0
50
214
2.64
7.97
9.8
7.5
—
—
—
0
0
72
367
2.31
7.88
1.3
1.3
16.79
28.05
iu/ml
0.75
20
105
147
1000
2.04
7.53
3.4
2.6
—
—
estimate
—
0
0
99
588
2.08
7.32
4.1
3.4
0.00
0.01
estimate
0.50
31
217
46
207
2.47
6.57
7.8
8.5
1.57
1.05
mmol/l
0.43
38
170
171
1270
1.95
6.36
6.3
4.6
6.69
6.65
mmol/l
0.07
163
1189
96
590
1.98
6.29
3.2
3.3
1231.02
1334.97
ng/l
0.11
84
503
63
334
2.16
6.14
1.3
1.2
12.41
7.38
u/ml
0.27
27
128
145
1031
1.88
6.05
7.9
6.7
1.21
1.21
mmol/l
0.26
128
890
206
1651
2.06
5.91
9.0
7.9
79.21
77.75
u/l
0.20
197
1569
125
853
1.87
5.88
4.7
3.2
0.03
0.03
estimate
0.01
30
206
117
794
1.84
5.51
4.4
3.6
24.59
44.22
ng/l
1.50
82
534
250
2190
3.00
5.49
19.5
13.6
23.79
24.55
mg/l
0.13
221
1745
194
1545
1.92
5.37
3.6
3.2
44.92
46.19
u/l
0.10
180
1466
206
1682
1.96
5.18
5.9
4.1
14.89
14.71
pmol/l
0.44
191
1537
85
530
1.88
5.18
2.9
2.6
320.37
348.62
umol/l
1.26
75
466
149
1102
1.79
5.17
4.7
3.3
0.00
0.00
estimate
-0.00
36
234
150
1113
1.79
5.13
4.7
3.3
0.00
0.00
estimate
-0.00
36
236
77
467
1.91
5.10
4.9
3.2
1.02
1.02
kg/l
0.71
49
307
152
1140
1.77
4.94
7.5
6.6
10.80
11.67
umol/l
0.76
142
1089
234
2017
2.23
4.82
6.8
5.0
2.01
1.90
mu/l
0.44
218
1856
144
1073
1.74
4.71
3.5
2.9
124.35
117.96
ug/l
0.12
135
1012
149
1125
1.73
4.61
4.8
3.3
0.00
0.00
estimate
-0.00
34
215
127
919
1.72
4.58
6.9
6.0
1.21
1.21
mmol/l
0.04
115
853
123
892
1.70
4.33
2.3
2.0
103.78
94.76
pmol/l
0.88
62
491
35
172
2.19
4.07
1.4
1.4
—
—
—
0
0
19
71
2.80
3.91
1.9
1.4
—
—
—
0
0
124
920
1.65
3.89
2.3
2.4
76.97
75.00
nmol/l
0.31
118
846
98
686
1.67
3.84
3.8
4.0
10.92
9.73
mg/mmol
0.09
65
440
71
456
1.76
3.80
1.9
1.6
1.16
1.36
mg/l
0.26
62
360
89
609
1.69
3.79
2.4
2.0
165.67
187.57
u/l
0.32
84
573
47
266
1.93
3.76
9.4
7.0
104.38
104.79
mmol/l
0.28
47
266
124
931
1.62
3.64
6.2
4.8
35.97
36.06
g/l
0.06
117
886
25
112
2.36
3.61
11.3
11.2
92.26
93.14
%
0.15
25
112
237
2111
2.03
3.57
18.1
13.3
83.08
82.85
ml/min/173m2
0.06
227
1934
237
2113
2.02
3.52
5.5
4.7
6.06
5.91
mmol/l
0.79
223
1956
53
321
1.81
3.43
2.0
1.7
1302.68
1171.92
nmol/l
0.42
44
248
84
581
1.65
3.38
3.6
2.9
0.68
0.58
e6/l
0.10
72
427
232
2061
1.91
3.38
6.9
5.9
39.44
38.98
mmol/mol
0.38
222
1947
31
159
2.07
3.25
3.0
2.7
74.50
64.71
ml/min/173m2
0.76
14
72
171
1409
1.59
3.24
3.7
3.2
—
—
—
0
0
254
2340
2.53
3.23
14.1
10.7
26.65
26.27
u/l
0.14
249
2274
25
118
2.23
3.22
2.2
3.1
2.80
1.62
mmol/l
0.74
20
91
77
528
1.64
3.19
2.6
2.1
—
—
—
0
0
37
206
1.92
3.10
4.8
3.0
6.02
5.69
kpa
0.96
37
198
106
790
1.56
3.09
3.2
3.2
33.41
33.06
u/l
0.03
94
761
36
199
1.93
3.08
4.6
3.0
2.31
1.71
mmol/l
0.40
28
164
42
245
1.85
3.06
5.8
4.7
32.91
31.96
%
0.19
32
164
95
703
1.54
2.81
3.4
3.8
2.35
2.35
mmol/l
0.03
87
662
233
2103
1.81
2.80
4.9
4.0
1.34
1.27
mmol/l
0.66
220
1955
30
165
1.92
2.62
8.5
6.7
9.21
9.60
mmol/l
0.10
30
159
41
250
1.76
2.59
2.3
1.8
—
—
—
0
0
68
474
1.58
2.59
1.4
1.2
4.96
1.14
u/ml
0.41
18
135
15
62
2.50
2.59
1.5
1.7
—
—
—
0
0
241
2209
1.87
2.59
5.7
4.7
1.42
1.45
mmol/l
0.74
227
2063
152
1262
1.47
2.48
10.5
9.9
4.14
4.10
e9/l
0.08
132
1099
52
343
1.64
2.47
2.4
1.9
—
—
—
0
0
18
84
2.22
2.41
2.1
1.8
0.73
1.96
ug/l
0.54
18
70
19
91
2.17
2.39
1.5
1.5
3.40
5.11
iu/ml
—
7
15
241
2222
1.81
2.35
5.7
4.8
4.51
4.64
mmol/l
1.21
229
2087
243
2246
1.85
2.34
6.3
5.3
2.62
2.72
mmol/l
0.95
229
2101
52
350
1.60
2.28
3.3
2.6
1.25
1.01
e6/l
0.18
32
191
7
18
3.96
2.26
1.3
1.1
—
—
—
0
0
19
95
2.08
2.16
4.3
3.3
1.02
1.02
ratio
0.07
19
89
57
398
1.55
2.14
4.5
3.5
1174.70
462.67
ng/l
0.28
40
308
38
240
1.68
2.13
2.3
1.8
—
—
—
0
0
46
306
1.61
2.12
2.7
2.5
2.31
2.29
g/l
0.06
46
285
94
730
1.44
2.10
6.1
5.1
1.63
2.67
ug/l
1.12
86
661
21
111
1.97
2.07
1.3
1.4
—
—
—
0
0
7
20
3.56
2.07
2.1
1.8
8.24
7.15
mmol/l
—
7
20
12
50
2.47
2.05
1.5
1.1
—
—
—
0
0
62
446
1.51
2.03
1.9
1.8
472.42
58098106.99
pmol/l
0.96
53
389
59
420
1.52
2.03
1.7
1.5
—
—
—
0
0
10
38
2.69
2.02
1.3
1.1
—
—
—
0
0
11
45
2.51
1.95
1.7
1.6
69.86
54.70
ug/l
0.36
11
45
5
11
4.61
1.95
1.0
2.7
91.80
95.45
%
—
5
11
47
324
1.55
1.87
3.4
2.8
7.25
2.63
e6/l
0.65
28
168
12
53
2.32
1.83
2.0
1.8
—
—
—
0
0
76
583
1.42
1.78
1.6
1.6
23.07
19.55
nmol/l
1.00
65
507
26
157
1.73
1.73
1.5
1.2
123.95
159.20
u/ml
0.26
13
60
33
215
1.61
1.67
3.6
3.4
—
—
—
0
0
10
41
2.49
1.66
1.3
1.3
—
—
—
0
0
28
176
1.66
1.62
5.6
2.5
4.97
4.68
kpa
0.30
28
170
83
658
1.38
1.59
4.1
2.7
0.00
0.02
estimate
0.99
30
185
11
53
2.12
1.40
1.5
1.2
—
—
—
0
0
17
97
1.80
1.38
1.6
1.3
—
—
—
0
0
54
408
1.40
1.37
3.6
3.0
2.45
2.44
mmol/l
0.22
48
371
14
75
1.91
1.37
1.0
2.1
3.75
3.46
g/l
0.39
14
68
14
75
1.91
1.37
1.0
2.1
4.22
4.31
g/l
0.14
14
68
5
17
2.98
1.36
1.0
1.0
—
—
—
0
0
13
68
1.96
1.36
3.0
2.2
4.04
5.38
iu/l
—
6
32
17
99
1.77
1.30
1.0
1.1
—
—
—
0
0
9
45
2.03
1.24
1.1
1.2
—
—
—
0
0
73
589
1.33
1.23
5.4
4.4
22.02
20.81
%
0.26
32
263
33
238
1.44
1.09
5.9
4.5
232.61
247.25
u/l
0.28
33
223
11
59
1.90
1.09
1.3
1.1
—
—
—
0
0
11
59
1.90
1.09
1.3
1.1
—
—
—
0
0
7
33
2.15
1.06
1.3
1.6
—
—
—
0
0
23
157
1.51
1.00
3.3
3.9
1.22
1.23
mmol/l
0.19
16
137
19
124
1.57
1.00
3.0
2.3
—
9.57
—
0
10
21
141
1.53
0.98
3.2
3.2
125.38
156.40
ng/l
0.36
21
124
7
36
1.97
0.97
3.6
1.9
—
—
—
0
0
12
71
1.72
0.90
2.5
2.9
—
—
—
0
0
108
949
1.23
0.89
1.9
1.9
1.28
1.34
mmol/l
0.38
87
812
10
56
1.82
0.89
1.5
1.5
—
—
—
0
0
10
56
1.82
0.89
2.8
1.9
705.40
224.80
ug/l
—
10
56
8
45
1.80
0.85
1.5
1.5
—
—
—
0
0
18
122
1.51
0.82
4.0
2.1
23.01
63.57
u/ml
1.19
18
116
53
436
1.27
0.78
4.1
3.0
0.66
0.75
ug/l
0.50
29
267
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
10
59
1.72
0.77
5.7
2.0
0.19
0.38
iu/ml
—
5
30
5
24
2.10
0.75
4.6
2.3
1.23
1.17
mmol/l
—
5
24
5
24
2.10
0.75
4.6
2.3
108.40
106.00
mmol/l
—
5
24
5
25
2.02
0.73
1.0
1.0
—
1.76
—
0
10
5
26
1.94
0.71
2.8
2.7
2.22
1.23
mmol/l
—
5
26
5
27
1.87
0.69
1.2
1.3
—
—
—
0
0
7
43
1.64
0.67
3.6
1.7
—
—
—
0
0
12
78
1.56
0.66
2.8
2.8
25.59
25.08
mmol/l
0.15
12
78
5
29
1.74
0.64
1.0
1.2
—
—
—
0
0
43
359
1.24
0.57
1.7
1.6
—
—
—
0
0
6
37
1.64
0.56
1.3
1.2
4.57
3.49
mmol/l
—
6
37
20
151
1.35
0.56
2.3
1.4
—
—
—
0
0
15
108
1.41
0.54
2.9
1.6
—
—
—
0
0
31
253
1.25
0.51
1.6
1.9
—
—
—
0
0
18
136
1.35
0.50
1.7
1.7
1342.18
999.10
mu/l
0.69
13
116
15
110
1.39
0.50
3.9
2.3
0.61
0.59
%
0.07
15
110
7
45
1.57
0.49
1.3
1.4
—
—
—
0
0
7
49
1.44
0.46
1.1
1.3
—
—
—
0
0
15
112
1.36
0.45
3.9
2.3
1.47
1.12
%
0.63
15
112
7
51
1.38
0.44
1.7
1.5
—
—
—
0
0
5
31
1.62
0.43
1.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
2.7
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
5
35
1.44
0.39
1.6
1.1
—
—
—
0
0
5
35
1.44
0.39
1.6
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.5
—
—
—
0
0
10
72
1.40
0.37
1.1
1.7
—
—
—
0
0
5
37
1.36
0.37
2.2
3.2
16.94
15.91
%
—
5
37
9
70
1.30
0.37
1.1
1.2
—
—
—
0
0
7
52
1.36
0.31
1.6
1.6
—
—
—
0
0
32
279
1.17
0.30
1.5
2.1
3.59
3.47
ratio
0.15
23
224
34
298
1.16
0.30
1.6
2.0
1.29
1.44
%
1.04
28
263
8
62
1.30
0.28
2.8
3.6
43.44
64.22
mg/l
—
8
52
8
62
1.30
0.28
2.8
3.6
31.24
31.50
mg/l
—
8
52
9
76
1.19
0.25
2.2
1.6
—
—
—
0
0
7
95
0.73
0.22
1.7
1.4
237.56
315.21
mu/l
—
7
85
10
79
1.28
0.22
1.3
1.6
—
—
—
0
0
23
201
1.16
0.22
1.3
1.9
3.63
3.45
mmol/l
0.20
13
145
0
11
0.00
0.21
0.0
1.7
—
43.45
—
0
11
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
15.80
—
0
10
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
4.2
—
0.58
—
0
12
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
48.50
—
0
13
31
279
1.13
0.20
1.7
2.0
—
—
—
0
0
6
52
1.16
0.19
1.2
1.2
—
—
—
0
0
7
60
1.17
0.18
1.0
1.4
—
—
—
0
0
9
81
1.11
0.15
2.8
1.7
—
—
—
0
0
5
48
1.04
0.09
1.8
2.8
124.20
132.00
g/l
—
5
38
5
63
0.79
0.08
1.6
1.5
—
—
—
0
0
12
109
1.11
0.06
1.1
2.0
0.24
0.24
mg/l
—
6
53
22
208
1.06
0.05
2.9
2.0
48.94
34.49
u/l
0.35
17
176
11
102
1.08
0.03
1.0
1.1
1.58
1.55
g/l
0.11
11
102
11
103
1.07
0.02
1.0
1.1
0.81
0.93
g/l
1.23
11
103
14
134
1.05
0.00
1.4
1.9
—
—
—
0
0
16
162
0.99
0.00
1.6
1.9
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
97.33
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
0.75
—
0
7
0
6
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
78
0.89
-0.00
3.3
1.7
—
—
—
0
0
6
64
0.94
-0.00
1.7
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
1.80
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint M13_RUPTUREMUSC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_RUPTUREMUSC | 1.322 [1.05, 1.67] | 0.019 |
| Birth year | 0.999 [0.99, 1.01] | 0.778 |
During the follow-up period (1.1.1998 — 31.12.2019), 96 out of 564 females with M13_RUPTUREMUSC died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_RUPTUREMUSC | 1.218 [1.01, 1.46] | 0.036 |
| Birth year | 0.992 [0.98, 1.0] | 0.09 |
During the follow-up period (1.1.1998 — 31.12.2019), 150 out of 748 males with M13_RUPTUREMUSC died.
Mortality risk
Mortality risk for people of age
years, who have M13_RUPTUREMUSC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.121% | 0.238% |
| 5 | 0.7% | 1.591% |
| 10 | 1.947% | 4.175% |
| 15 | 4.052% | 7.574% |
| 20 | 7.25% | 13.317% |
Relationships between endpoints
↥Index endpoint: M13_RUPTUREMUSC – Other rupture of muscle
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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