Other forms of systemic lupus erythematosus

SLE_OTH

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M32.8
  • Cause of death: ICD-10 M32.8

2 out of 7 registries used, show all original rules.

344

4. Check minimum number of events

None

344

5. Include endpoints

None

344

6. Filter based on genotype QC (FinnGen only)

305

Control definitions (FinnGen only)

Control exclude
SLE_FG

Extra metadata

First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M32
Name in latin
Aliae formae lupi erythematosi disseminati (LED)

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1584 1344 221
Only index persons 1393 1210 183
Unadjusted period prevalence (%)
Whole population 0.03 0.04 0.01
Only index persons 0.04 0.04 0.01
Median age at first event (years)
Whole population 48.85 48.53 50.99
Only index persons 47.72 47.64 48.24

-FinnGen-

Key figures

All Female Male
Number of individuals 305 269 36
Unadjusted period prevalence (%) 0.09 0.10 0.02
Median age at first event (years) 45.63 44.69 52.62

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
317
Matched controls
3170
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
+∞
307.7
310
*
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
+∞
307.7
255
*
P01BA02
ATC
hydroxychloroquine; oral
102.9
307.7
268
160
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
62.3
305.4
256
200
L04AX01
ATC
azathioprine; systemic
58.2
229.7
139
42
L04AA06
ATC
mycophenolic acid; systemic
58.8
143.8
83
19
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
16.4
118.6
121
115
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
+∞
111.1
100
*
M32.0
ICD-10 Finland
Drug-induced systemic lupus erythematosus
+∞
101.7
92
*
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
44.2
99.7
61
17
L04AX03
ATC
methotrexate; systemic
10.6
86.8
121
174
7100A
ICD-9 Finland
Diffuse diseases of connective tissue, Systemic lupus erythematosus
+∞
83.0
76
*
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
10.8
75.5
97
124
H02AB07
ATC
prednisone; oral
8.4
74.0
132
249
M32
ICD-10 Finland
Systemic lupus erythematosus
+∞
71.6
66
*
M05BA04
ATC
alendronic acid; oral
9.3
67.4
98
145
L01BA01
ATC
methotrexate; systemic
18.3
64.7
55
36
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
7.4
64.1
229
826
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
8.3
58.4
92
148
H02AB06
ATC
prednisolone; systemic
8.3
56.6
261
1143
L88
ICPC
Rheumatoid/seropositive arthritis
11.7
52.6
59
61
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
8.3
51.6
79
122
73410
ICD-8 Finland
Diffuse diseases of connective tissue, Systemic lupus erythematosus
+∞
49.3
46
*
C08CA05
ATC
nifedipine; systemic
9.7
44.6
57
70
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
13.6
44.6
44
37
L93.0
ICD-10 Finland
Discoid lupus erythematosus
104.6
42.0
45
5
N08.5*M32.1
ICD-10 Finland
Glomerular disorders in systemic lupus erythematosus
+∞
41.6
39
*
H02AB04
ATC
methylprednisolone; systemic
4.8
34.1
100
279
R50.9
ICD-10 Finland
Fever, unspecified
4.7
34.0
104
300
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
6.9
31.6
54
92
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.0
30.8
208
1031
M35.1
ICD-10 Finland
Other overlap syndromes
114.2
29.2
31
*
B01AA03
ATC
warfarin; systemic
4.5
28.4
84
233
ZX120
NOMESCO Finland
Intravenous
5.0
28.4
71
172
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.8
26.5
112
400
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.3
25.3
79
227
L04AA01
ATC
[U] ciclosporin
41.2
24.4
30
8
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
3.9
24.0
89
289
TPH04
NOMESCO Finland
Cathetrisation of vein
3.4
22.0
108
419
L04AD01
ATC
ciclosporin; systemic
22.8
21.7
31
15
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
7.0
20.5
33
52
XX9XE
NOMESCO Finland
Other ultrasound examination
29.3
20.4
27
10
J01FF01
ATC
clindamycin; systemic
3.0
19.3
129
592
M05BA07
ATC
risedronic acid; oral
7.2
18.6
29
44
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.8
18.2
65
203
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.1
17.9
56
159
J99.1*M32.1
ICD-10 Finland
Respiratory disorders in systemic: lupus erythematosus
+∞
17.9
17
*
G73.7*M32.1
ICD-10 Finland
Myopathy in systemic lupus erythematosus
+∞
17.9
17
*
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
3.8
17.7
63
196
C03CA01
ATC
furosemide; systemic
2.9
17.7
113
502
B07.9
ICD-10 Finland
Verruca simplex
6.3
17.5
31
54
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.8
17.4
128
612
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
6.4
17.3
30
51
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
3.4
16.0
66
225
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.6
15.9
185
1100
F02.89*M32.8
ICD-10 Finland
Dementia in systemic lupus erythematosus
+∞
15.8
15
*
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
6.9
15.6
25
39
L99
ICPC
Musculoskeletal disease other
7.4
15.5
23
33
J01MA12
ATC
levofloxacin; systemic
3.0
15.4
84
339
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
21.4
15.3
22
11
P01BA01
ATC
chloroquine; systemic
33.5
15.0
19
6
M05BX04
ATC
denosumab; parenteral
4.5
14.9
39
96
Z3231
NOMESCO Finland
Registered nurse
2.6
14.8
118
580
G05.8*M32.1
ICD-10 Finland
Encephalitis in systemic lupus erythematosus
+∞
14.7
14
*
N08.5
ICD-10 Finland
Glomerular disorders in systemic connective tissue disorders
+∞
14.7
14
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.7
14.5
101
462
D68.8
ICD-10 Finland
Other specified coagulation defects
12.8
14.4
25
21
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.8
14.3
96
431
A02BC02
ATC
pantoprazole; systemic
2.9
14.3
250
1774
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
4.8
14.2
34
78
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
4.7
14.0
34
79
A02BC01
ATC
omeprazole; systemic
2.6
13.9
116
579
Z01.8
ICD-10 Finland
Other specified special examinations
2.7
13.8
99
459
E0000UV, ,
ATC
2.5
13.7
177
1079
R06.0
ICD-10 Finland
Dyspnoea
2.6
13.7
116
583
B01AB05
ATC
enoxaparin; parenteral
2.5
13.7
128
674
J05AB11
ATC
valaciclovir; oral
2.8
13.5
82
348
A41.9
ICD-10 Finland
Sepsis, unspecified
6.7
13.5
22
35
D07AC01
ATC
betamethasone; topical
2.4
13.1
148
844
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
5.4
13.1
27
54
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.4
13.1
52
172
D07AB08
ATC
desonide; topical
3.1
13.1
61
223
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
3.7
12.9
44
132
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.8
12.7
41
118
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.8
12.7
42
123
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
5.6
12.7
25
48
XQ848
NOMESCO Finland
Dermatological photography
6.0
12.6
23
41
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.1
12.6
62
234
Z3229
NOMESCO Finland
Other healthcare associate professional
3.7
12.4
43
130
NF1AA
NOMESCO Finland
Hip X-ray examination
3.7
12.4
43
130
N02AX02
ATC
tramadol; systemic, rectal
2.3
12.3
161
972
R4120
NOMESCO Finland
Occupational therapy
3.8
12.1
40
117
B02.9
ICD-10 Finland
Zoster without complication
3.7
12.0
40
118
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.6
11.6
84
387
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.4
11.6
46
152
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
4.2
11.4
32
83
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.7
11.4
39
117
M05BB03
ATC
alendronic acid and colecalciferol; oral
9.1
11.2
23
27
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
6.0
11.1
20
35
M81.9
ICD-10 Finland
Osteoporosis, unspecified
4.3
11.0
30
76
A07AA02
ATC
nystatin; oral
3.9
11.0
34
95
L01AA01
ATC
cyclophosphamide; systemic
62.1
10.7
12
*
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
8.7
10.5
22
27
L93.1
ICD-10 Finland
Subacute cutaneous lupus erythematosus
+∞
10.5
10
*
J01MA02
ATC
ciprofloxacin; systemic
2.2
10.4
138
823
J05AB01
ATC
aciclovir; systemic
2.3
10.4
106
568
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
4.2
10.3
28
71
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
10.6
10.2
19
19
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
3.8
10.1
32
91
E000001, ,
ATC
2.4
10.0
86
427
UJF30
NOMESCO Finland
Ileoscopy through colon
2.9
9.9
50
190
1XC02, ,
NOMESCO Finland
27.0
9.9
13
5
N32.9
ICD-10 Finland
Bladder disorder, unspecified
27.0
9.9
13
5
205
Kela drug reimbursment
Chronic hypertension
2.4
9.8
81
394
Z3226
NOMESCO Finland
Physiotherapist
2.4
9.8
78
374
J01FA06
ATC
roxithromycin; oral
2.1
9.7
154
977
WZC00
NOMESCO Finland
Treatment plan or consultation
2.1
9.7
142
874
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
5.3
9.7
20
40
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
4.9
9.7
22
48
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
9.5
9.7
19
21
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
3.5
9.6
35
109
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
15.7
9.6
15
10
H04.10
ICD-10 Finland
Dry eye syndrome
2.6
9.5
65
289
H26.3
ICD-10 Finland
Drug-induced cataract
18.2
9.5
14
8
D02AX
ATC
Other emollients and protectives
5.4
9.5
19
37
L01BB01, ,
ATC
103.0
9.5
10
*
73491
ICD-8 Finland
Diffuse diseases of connective tissue, Collagenosis NUD
103.0
9.5
10
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.9
9.5
50
195
B01AB04
ATC
dalteparin; parenteral
4.3
9.4
25
62
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
22.5
9.4
13
6
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.3
9.4
89
459
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
10.0
9.4
18
19
Z50.1
ICD-10 Finland
Other physical therapy
3.8
9.3
29
81
L28
ICPC
Limited function/disability (L)
2.4
9.2
76
370
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.0
9.1
44
163
L04AA13
ATC
[U] leflunomide
7.8
9.1
20
27
318
Kela drug reimbursment
Teriparatide
37.9
9.1
11
*
H05AA02
ATC
teriparatide; parenteral
37.9
9.1
11
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.8
9.1
28
78
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.6
8.9
56
239
A02BC03
ATC
lansoprazole; oral
2.1
8.9
108
615
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
9.9
8.9
17
18
XCK00
NOMESCO Finland
Perimetry
3.5
8.9
31
94
R4110
NOMESCO Finland
Physiotherapy
2.2
8.9
106
600
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.0
8.8
158
1039
L95
ICPC
Osteoporosis
4.0
8.8
26
70
N02AA05
ATC
oxycodone; systemic
2.5
8.8
66
307
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.5
8.7
60
267
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.2
8.7
37
127
J01MA06
ATC
norfloxacin; oral
2.5
8.7
65
301
Z2221
NOMESCO Finland
Medical doctor
2.1
8.7
111
644
H02AB09
ATC
hydrocortisone; systemic
6.7
8.6
21
33
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
4.1
8.6
24
62
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.8
8.5
26
72
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
4.9
8.5
19
41
6BA02, ,
NOMESCO Finland
92.4
8.5
9
*
R4190
NOMESCO Finland
Nutritional therapy
4.0
8.4
24
63
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
3.3
8.4
33
108
7108X
ICD-9 Finland
Diffuse diseases of connective tissue, Other specified diffuse diseases of connective tissue
+∞
8.4
8
*
G73.7
ICD-10 Finland
Myopathy in other diseases classified elsewhere
+∞
8.4
8
*
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
3.8
8.3
26
73
A46
ICD-10 Finland
Erysipelas
2.6
8.2
52
223
L27.0
ICD-10 Finland
Generalized skin eruption due to drugs and medicaments
12.1
8.2
14
12
I35.0
ICD-10 Finland
Aortic (valve) stenosis
4.1
8.1
23
60
N18.0
ICD-10 Finland
End-stage renal disease
34.3
8.1
10
*
J01MA14
ATC
moxifloxacin; systemic
2.9
8.1
40
150
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.5
8.0
58
264
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.8
8.0
25
70
D07AC13
ATC
mometasone; topical
2.1
8.0
110
652
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.4
8.0
66
319
S97
ICPC
Chronic ulcer skin
3.3
7.9
31
101
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
9.8
7.9
15
16
D07AD01
ATC
clobetasol; topical
2.3
7.8
71
357
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.0
7.8
147
972
Z2446
NOMESCO Finland
Social worker
3.2
7.8
32
108
M34.9
ICD-10 Finland
Systemic sclerosis, unspecified
46.1
7.7
9
*
XPX04
NOMESCO Finland
Angioscopy
46.1
7.7
9
*
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.0
7.7
35
125
M05BA06
ATC
ibandronic acid; systemic
7.0
7.7
18
27
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.5
7.6
50
217
EB1WA, ,
NOMESCO Finland
25.7
7.6
10
*
UJD02
NOMESCO Finland
Gastroscopy
3.9
7.6
23
63
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
10.4
7.6
14
14
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
3.4
7.6
28
88
C08CA01
ATC
amlodipine; oral
2.0
7.6
120
746
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.3
7.4
29
95
N08.5*M31.1
ICD-10 Finland
Glomerular disorders in thrombotic thrombocytopenic purpura
+∞
7.3
7
*
L93.2
ICD-10 Finland
Other local lupus erythematosus
+∞
7.3
7
*
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.5
7.3
18
42
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
4.7
7.3
17
38
A01AB09
ATC
miconazole; local oral
2.8
7.3
39
153
C09AA02
ATC
enalapril; systemic
2.3
7.2
59
283
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.2
7.2
70
362
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
6.3
7.2
18
30
M81.4
ICD-10 Finland
Drug-induced osteoporosis
20.6
7.2
10
5
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.5
7.2
49
217
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
2.4
7.2
52
237
J01DB01
ATC
cefalexin; oral
2.5
7.1
279
2353
K11.2
ICD-10 Finland
Sialoadenitis
4.0
7.1
20
52
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
3.2
7.1
28
92
SPAT1255
SPAT
Intravenous administration of medicine
3.3
7.0
27
87
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
4.1
7.0
19
48
ZX140
NOMESCO Finland
Intra articular
14.2
6.9
11
8
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.3
6.9
27
88
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.8
6.9
35
133
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
7.0
6.9
16
24
R23.3
ICD-10 Finland
Spontaneous ecchymoses
5.9
6.9
18
32
PJA10
NOMESCO Finland
Exploration of lymph nodes
11.3
6.9
12
11
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
11.3
6.9
12
11
WX892
NOMESCO Finland
Monitored bed care
3.2
6.8
28
94
NH3AE
NOMESCO Finland
Feet ultrasound examination
41.0
6.8
8
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.3
6.8
59
291
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.5
6.7
43
184
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.3
6.7
53
250
H53.1
ICD-10 Finland
Subjective visual disturbances
2.8
6.7
34
129
A11CC03
ATC
alfacalcidol; systemic
6.7
6.7
16
25
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
3.7
6.7
21
59
J02AC01
ATC
fluconazole; systemic
1.8
6.6
167
1193
XF404
NOMESCO Finland
Ambulatory ECG
2.8
6.6
34
130
D64.9
ICD-10 Finland
Anaemia, unspecified
2.7
6.6
37
148
XG410
NOMESCO Finland
Flow-volume spirometry
4.3
6.6
17
41
C02DE02, ,
ATC
12.6
6.6
11
9
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
12.6
6.6
11
9
XF400
NOMESCO Finland
ECG with 12 standard connections
2.3
6.6
53
252
N18.8
ICD-10 Finland
Other chronic renal failure
9.0
6.6
13
15
A01AC01
ATC
triamcinolone; local oral
9.0
6.6
13
15
JN3AD
NOMESCO Finland
Abdominal CT examination
2.4
6.6
47
212
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
3.7
6.6
21
60
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.7
6.5
36
143
A02BC05
ATC
esomeprazole; systemic
1.8
6.5
144
987
M01AH02
ATC
rofecoxib; oral
2.4
6.5
49
227
69540
ICD-8 Finland
Erythematous condition, Lupus erythematosus
71.2
6.4
7
*
TQW80
NOMESCO Finland
Local dermatologic skincare
5.7
6.4
17
31
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
6.2
6.4
16
27
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.4
6.4
45
202
I25.2
ICD-10 Finland
Old myocardial infarction
4.0
6.4
18
47
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.9
6.3
112
714
ZXX01
NOMESCO Finland
Extent of proceudre, 1 unit
11.3
6.3
11
10
NH1AE
NOMESCO Finland
Ankle joint ultrasound examination
11.3
6.3
11
10
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.1
6.3
68
365
L84
ICD-10 Finland
Corns and callosities
3.8
6.3
19
52
N085, M328,
ICD-10 Finland
+∞
6.3
6
*
N16.4*M32.1
ICD-10 Finland
Renal tubulo-interstitial disorders in systemic lupus erythematosus
+∞
6.3
6
*
I32.8*M32.1
ICD-10 Finland
Pericarditis (in) systemic lupus erythematosus
+∞
6.3
6
*
A63.0
ICD-10 Finland
Anogenital (venereal) warts
3.7
6.3
20
57
WX002
NOMESCO Finland
Sedation and analgesia
2.1
6.3
66
351
ZX108
NOMESCO Finland
Inhalation
27.3
6.3
8
*
WW200
NOMESCO Finland
Immunization
6.5
6.2
15
24
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
2.2
6.2
59
301
Z49.1
ICD-10 Finland
Extracorporeal dialysis
12.9
6.1
10
8
M02.9
ICD-10 Finland
Reactive arthropathy, unspecified
10.3
6.1
11
11
M80.0
ICD-10 Finland
Postmenopausal osteoporosis with pathological fracture
6.2
6.1
15
25
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
6.2
6.1
15
25
N03AX16
ATC
[U] pregabalin
2.0
6.0
84
494
E000007, ,
ATC
2.8
6.0
30
113
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
2.7
6.0
33
131

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
222
145
48.75
284.87
10.2
1.6
24.32
5.74
iu/ml
9.28
141
39
114
108
15.92
111.53
2.1
1.3
24.10
2.55
u/ml
1.69
45
11
113
108
15.70
109.84
2.1
1.3
21.48
3.60
u/ml
2.62
55
20
114
115
14.92
106.93
2.1
1.3
37.49
1.40
u/ml
—
26
6
90
96
12.70
80.01
2.1
1.2
70.43
59.54
u/ml
—
29
10
185
465
8.15
79.52
2.9
1.4
964.51
561.19
titre
2.51
133
101
60
56
12.98
57.46
1.5
1.1
7.35
10.30
u/ml
0.23
43
20
51
38
15.80
55.79
2.5
2.1
—
—
—
0
0
221
915
5.67
48.41
15.4
5.4
—
—
—
0
0
282
1465
9.38
46.62
19.8
5.6
0.57
0.54
e9/l
1.05
271
1268
282
1473
9.28
46.09
19.8
5.6
0.04
0.04
e9/l
0.27
271
1271
282
1505
8.91
43.99
19.9
5.6
1.59
1.99
e9/l
4.93
274
1340
283
1534
8.88
42.80
20.0
5.9
0.14
0.18
e9/l
7.77
275
1347
94
229
5.41
38.09
8.0
4.5
0.44
0.69
%
0.58
43
59
286
1652
8.48
37.69
22.2
9.2
3.91
3.92
e9/l
0.04
275
1451
97
251
5.13
36.49
9.1
4.5
0.80
0.79
%
0.02
45
73
34
26
14.53
36.25
1.6
1.2
—
—
—
0
0
92
236
5.08
34.84
9.4
4.6
0.00
0.14
%
2.00
39
56
34
29
13.01
33.95
1.6
1.1
—
—
—
0
0
153
625
3.80
30.23
4.6
2.6
5.40
8.05
e6/l
1.06
146
577
87
242
4.58
29.40
10.2
4.9
0.00
0.13
%
0.60
32
53
207
1058
3.76
28.44
8.6
3.9
126.89
65.24
e6/l
0.58
167
727
221
1184
3.86
28.11
7.3
4.3
34.47
36.44
g/l
6.11
212
1118
35
43
9.03
27.03
1.9
1.3
—
—
—
0
0
238
1373
3.94
26.26
4.3
2.6
82.08
77.88
nmol/l
1.62
232
1249
256
1551
4.38
26.25
8.8
3.8
0.00
0.00
estimate
0.50
61
330
259
1582
4.48
26.25
9.0
3.8
0.00
0.00
estimate
-0.00
63
316
106
367
3.84
26.24
4.3
3.1
3.92
5.69
e9/l
0.98
96
331
183
904
3.42
25.72
6.8
3.1
38.76
114.06
e6/l
0.50
165
693
256
1567
4.29
25.47
9.0
3.8
22.31
4.83
estimate
0.35
65
336
131
535
3.47
24.99
6.1
2.7
496.40
515.66
mosm/kgh2o
0.53
124
477
162
765
3.29
24.14
6.4
3.0
0.45
0.39
e6/l
0.10
142
549
220
1261
3.43
23.32
7.0
3.4
6.35
6.22
ph
1.09
126
720
146
660
3.25
23.23
5.7
3.9
—
—
—
0
0
229
1380
3.38
21.59
13.3
6.5
1.22
1.22
mmol/l
0.14
211
1178
283
1958
5.15
21.45
13.8
4.5
—
1.81
—
0
5
167
846
3.06
21.33
2.8
2.0
111.22
245.10
u/l
1.03
162
801
47
103
5.18
20.85
1.3
1.3
—
—
—
0
0
91
330
3.47
20.44
10.3
5.6
1.10
1.05
mmol/l
1.08
86
299
147
709
3.00
20.27
3.3
3.3
1265.68
955.78
ng/l
0.51
133
598
166
863
2.94
19.83
6.6
2.9
0.25
0.11
—
8
18
73
243
3.60
18.58
5.6
3.5
7.36
7.39
ph
2.83
51
141
77
275
3.38
17.48
3.0
2.0
0.00
0.03
estimate
0.49
23
66
141
709
2.78
17.38
3.2
2.1
3.21
2.87
mg/l
0.51
132
612
142
728
2.72
16.71
13.1
4.7
—
—
—
0
0
79
295
3.23
16.62
2.4
1.5
—
—
—
0
0
51
144
4.03
16.36
3.4
2.1
0.00
0.00
estimate
-0.00
17
56
68
234
3.43
16.30
5.6
3.4
1.53
1.97
mmol/l
0.50
57
206
79
304
3.13
15.72
2.0
2.1
348.85
381.21
nmol/l
0.72
72
289
203
1278
2.64
15.22
23.3
10.2
0.00
0.00
e9/l
0.31
186
1039
87
360
2.95
15.19
3.3
1.9
—
—
—
0
0
192
1183
2.58
14.96
30.2
11.4
1.39
1.17
inr
4.81
176
966
159
899
2.54
14.85
4.0
3.0
—
—
—
0
0
35
82
4.67
14.23
4.5
2.4
362.67
272.38
mg/l
0.20
24
26
51
166
3.47
13.21
1.7
2.7
—
—
—
0
0
128
689
2.44
12.87
1.9
1.4
2.35
2.19
g/l
0.55
93
424
90
417
2.62
12.39
6.2
2.9
2.39
4.00
e6/l
1.28
61
183
190
1236
2.34
12.13
11.3
5.8
1.22
1.22
mmol/l
0.16
185
1138
54
194
3.15
11.89
1.9
3.1
68.13
74.13
e9/l
0.46
35
142
147
870
2.29
11.61
7.0
4.1
7.39
7.40
ph
0.44
112
597
150
901
2.26
11.36
8.0
3.1
0.00
0.01
estimate
0.74
55
266
17
11
16.24
10.95
1.2
1.3
29.47
27.82
s
0.48
17
11
88
432
2.44
10.54
4.9
3.1
0.83
0.82
mmol/l
0.48
82
409
180
1201
2.15
10.09
8.5
3.6
0.00
0.02
estimate
0.88
57
276
139
861
2.09
9.24
8.2
3.9
0.00
0.00
estimate
0.50
59
312
72
341
2.44
9.22
1.8
1.4
—
—
—
0
0
209
1511
2.12
9.09
7.6
6.0
9.42
10.00
umol/l
0.70
203
1432
116
680
2.11
8.85
2.1
1.7
1.48
1.08
mg/l
0.74
97
537
143
909
2.04
8.74
6.2
3.1
7.15
7.47
mmol/l
0.36
133
770
73
356
2.36
8.73
1.5
1.6
—
—
—
0
0
135
846
2.04
8.54
7.3
3.9
23.73
7.88
mg/mmol
1.17
102
482
203
1477
2.04
8.35
4.7
3.2
111.80
83.44
ug/l
1.45
196
1388
36
127
3.07
8.10
1.2
1.3
—
—
—
0
0
131
827
2.00
7.99
6.4
3.3
86.77
42.19
mg/l
1.14
102
497
23
61
3.99
7.95
6.0
4.1
—
—
—
0
0
134
858
1.97
7.81
13.3
6.2
—
—
—
0
0
152
1020
1.94
7.68
3.8
3.3
2.34
2.36
mmol/l
1.56
145
938
102
596
2.05
7.67
1.6
2.0
—
—
—
0
0
78
412
2.18
7.63
2.3
2.3
102.44
102.05
ug/g
0.01
66
329
21
54
4.09
7.56
1.2
1.5
354.23
266.25
u/ml
0.36
13
31
30
101
3.18
7.30
5.1
3.6
—
—
—
0
0
15
19
8.23
7.19
2.6
2.3
21.20
201.16
e6/l
3.11
15
19
18
43
4.38
7.11
1.8
1.3
—
—
—
0
0
11
8
14.18
6.94
1.0
1.6
—
—
—
0
0
10
6
17.15
6.78
1.2
1.2
—
—
—
0
0
147
1010
1.85
6.63
4.9
3.6
515.58
91.13
ng/l
0.43
110
649
88
512
1.99
6.57
1.6
1.7
—
—
—
0
0
49
227
2.37
6.49
1.3
1.5
—
—
—
0
0
10
7
14.69
6.44
2.8
3.1
2.00
5.14
%
—
10
7
22
66
3.51
6.40
4.0
2.1
9.29
1.86
index
—
7
36
51
242
2.32
6.39
2.6
2.4
6.24
6.21
ph
0.09
31
157
85
494
1.98
6.34
5.5
3.7
312.64
149.31
ng/l
0.63
64
351
10
8
12.85
6.12
2.7
2.8
38.40
23.13
%
—
10
8
44
201
2.38
6.00
12.5
7.6
—
—
—
0
0
19
54
3.68
5.98
6.7
3.5
3.52
4.54
e9/l
1.13
19
54
95
585
1.89
5.93
3.5
2.4
2.46
2.45
mmol/l
0.71
87
527
205
1593
1.81
5.88
7.3
4.5
6.16
6.45
mmol/l
1.46
197
1496
37
158
2.52
5.83
4.8
3.3
5.21
5.07
kpa
0.48
37
153
48
236
2.22
5.52
1.4
1.4
—
—
—
0
0
27
101
2.83
5.49
5.2
3.9
1.48
1.56
%
0.13
27
94
105
684
1.80
5.40
4.2
2.7
336.85
316.67
umol/l
1.05
95
608
133
930
1.74
5.35
2.6
2.2
—
—
—
0
0
60
326
2.04
5.34
10.0
6.1
104.63
104.25
mmol/l
0.17
60
326
14
26
5.58
5.29
2.7
4.5
—
—
—
0
0
35
154
2.43
5.18
4.9
3.4
7.40
7.43
ph
1.13
30
129
25
93
2.83
5.14
5.3
4.0
0.71
0.88
%
1.84
25
86
19
60
3.30
5.13
1.3
1.5
—
—
—
0
0
23
83
2.91
4.99
1.4
2.4
10.68
10.86
mg/l
0.03
23
78
128
901
1.71
4.94
2.9
2.4
59.19
61.84
u/l
0.20
122
834
15
33
4.72
4.93
1.7
1.5
—
—
—
0
0
15
33
4.72
4.93
1.7
1.5
—
—
—
0
0
15
33
4.72
4.93
1.7
1.5
—
—
—
0
0
15
33
4.72
4.93
1.7
1.5
—
—
—
0
0
49
255
2.09
4.88
2.6
2.3
0.19
0.22
g/l
1.94
44
241
21
75
2.93
4.65
6.2
3.3
60.62
59.12
%
0.21
21
75
103
695
1.71
4.57
6.8
3.8
1.02
1.02
kg/l
0.33
87
460
37
177
2.23
4.54
1.9
2.4
7.98
5.33
ug/l
0.42
32
157
172
1328
1.65
4.54
3.3
2.7
—
—
estimate
—
0
0
48
258
2.01
4.38
1.2
1.1
—
—
—
0
0
22
86
2.67
4.15
1.5
1.4
392.23
324.27
ug/g
1.12
13
48
14
36
4.02
4.05
1.1
1.1
—
—
—
0
0
301
2767
2.74
4.04
39.8
14.0
17.19
20.90
mg/l
2.04
278
2234
66
405
1.80
4.03
1.9
1.7
1202.53
1276.94
nmol/l
0.27
54
303
30
139
2.28
3.98
5.0
2.3
0.60
0.62
%
0.15
30
139
13
32
4.19
3.95
1.3
1.4
—
—
—
0
0
158
1224
1.58
3.91
2.5
2.0
101.79
98.20
pmol/l
0.36
79
629
20
77
2.70
3.89
2.6
1.7
136.10
172.64
ug/l
0.24
20
70
9
15
6.14
3.84
2.7
3.1
821.89
679.27
u/ml
—
9
15
13
33
4.06
3.84
3.5
2.5
108.31
106.91
mmol/l
0.44
13
33
13
33
4.06
3.84
3.5
2.5
3.88
3.90
mmol/l
0.04
13
33
13
33
4.06
3.84
3.5
2.5
1.22
1.19
mmol/l
0.72
13
33
10
20
5.13
3.72
1.3
1.1
—
—
—
0
0
12
30
4.12
3.63
1.2
1.1
—
—
—
0
0
7
9
7.92
3.57
2.9
3.0
0.65
0.60
mmol/l
—
7
9
17
63
2.79
3.55
3.2
2.6
10.68
8.47
pmol/l
0.25
17
63
15
52
2.98
3.51
1.0
1.9
—
—
—
0
0
64
407
1.72
3.44
1.3
1.2
—
—
—
0
0
14
48
3.01
3.34
1.1
1.2
—
—
—
0
0
23
104
2.31
3.24
1.3
1.4
—
—
—
0
0
7
11
6.48
3.20
6.1
1.5
16.11
16.23
%
—
7
11
7
11
6.48
3.20
1.1
1.1
—
—
—
0
0
109
807
1.53
3.13
1.9
1.6
19.26
21.68
nmol/l
1.11
96
685
118
892
1.51
3.07
4.9
3.3
—
0.80
—
0
5
8
16
5.10
3.07
2.1
4.1
1775.50
1056.63
mg
—
8
16
6
8
7.62
3.06
1.2
1.1
—
—
—
0
0
107
797
1.52
2.97
1.4
1.3
0.93
1.88
u/ml
0.97
28
243
11
32
3.52
2.93
1.1
1.0
—
—
—
0
0
6
10
6.09
2.71
1.0
2.6
—
—
—
0
0
9
24
3.83
2.69
1.1
1.2
—
—
—
0
0
259
2340
1.58
2.58
5.1
4.8
14.69
14.58
pmol/l
0.33
251
2177
14
56
2.57
2.56
1.1
1.2
—
—
—
0
0
17
76
2.31
2.49
3.0
2.9
7.40
7.42
ph
0.89
17
76
148
1215
1.41
2.36
2.3
2.1
—
—
—
0
0
9
28
3.28
2.32
1.1
1.2
110.89
108.96
pmol/l
—
9
28
8
23
3.54
2.28
1.1
1.1
—
—
—
0
0
42
267
1.66
2.26
11.7
7.1
7.41
7.41
ph
0.03
23
158
89
671
1.45
2.25
1.4
1.4
39.05
30.18
iu/ml
0.41
35
211
14
61
2.35
2.18
2.1
2.0
—
—
—
0
0
17
81
2.16
2.17
1.8
5.1
36.03
38.88
mg/l
0.19
12
69
17
81
2.16
2.17
1.7
5.1
31.04
26.93
mg/l
0.29
12
69
84
632
1.45
2.14
1.3
1.3
18.94
10.95
u/ml
0.44
38
247
8
194
0.40
2.12
1.5
1.9
—
—
—
0
0
6
16
3.80
1.94
7.2
1.6
6.42
8.28
mmol/l
—
6
16
14
65
2.21
1.91
1.5
1.2
—
—
—
0
0
6
17
3.58
1.84
3.7
1.3
162.17
90.02
ng/l
—
6
17
8
29
2.80
1.80
1.0
1.2
—
—
—
0
0
6
18
3.38
1.75
1.0
1.2
71.17
107.25
iu/ml
—
6
18
6
18
3.38
1.75
1.5
1.1
—
—
—
0
0
5
13
3.89
1.72
1.4
1.2
—
—
—
0
0
6
19
3.20
1.67
1.0
1.4
—
—
—
0
0
284
2685
1.55
1.61
6.3
5.9
1.96
1.83
mu/l
1.29
275
2528
8
32
2.54
1.60
3.5
3.3
—
—
—
0
0
6
20
3.04
1.59
1.2
1.5
96.00
64.45
umol/l
—
6
20
72
559
1.37
1.52
1.5
1.7
436.89
25786610.20
pmol/l
0.78
65
477
41
288
1.49
1.48
1.4
1.5
—
—
—
0
0
9
38
2.41
1.47
1.9
1.3
—
—
—
0
0
14
73
1.96
1.46
1.7
4.8
1.16
2.25
ratio
—
6
46
12
222
0.52
1.41
1.2
1.3
—
—
—
0
0
99
1181
0.76
1.41
3.2
3.1
—
—
—
0
0
38
267
1.48
1.38
3.3
4.1
34.59
6.72
ug/l
0.51
27
217
6
23
2.64
1.37
1.0
1.0
—
—
—
0
0
25
161
1.60
1.33
1.3
1.2
—
—
—
0
0
15
84
1.82
1.29
1.1
1.1
—
—
—
0
0
5
18
2.80
1.29
1.0
1.1
—
—
—
0
0
8
35
2.32
1.27
1.4
1.9
32.00
32.31
pg
—
8
35
5
19
2.66
1.22
1.6
1.4
13.91
27.22
ug/l
—
5
19
12
64
1.91
1.19
1.0
1.1
—
—
—
0
0
12
64
1.91
1.19
1.0
1.1
—
—
—
0
0
32
227
1.46
1.13
1.4
1.2
42.66
192.32
u/ml
1.47
26
210
8
40
2.03
1.13
1.0
1.0
—
—
—
0
0
7
32
2.21
1.08
3.1
2.4
—
—
—
0
0
7
35
2.02
1.00
1.3
1.1
—
—
—
0
0
5
23
2.19
0.98
1.2
1.2
—
—
—
0
0
19
125
1.55
0.96
1.1
1.4
155.00
251.15
miu/ml
—
9
61
211
1968
1.22
0.88
4.0
3.2
55.82
39.86
u/l
1.27
204
1877
14
88
1.62
0.86
1.4
1.2
—
—
—
0
0
20
138
1.48
0.84
2.9
4.5
—
—
—
0
0
35
269
1.34
0.82
12.9
7.0
-0.14
1.15
mmol/l
0.76
28
230
8
47
1.72
0.81
1.0
1.0
—
—
—
0
0
8
47
1.72
0.81
3.4
2.7
8.22
8.97
kpa
—
8
47
8
47
1.72
0.81
3.4
2.7
5.16
5.08
kpa
—
8
47
271
2605
1.28
0.79
4.7
4.1
1.29
1.25
mmol/l
0.42
257
2419
0
25
0.00
0.79
0.0
1.0
—
0.22
—
0
12
8
48
1.68
0.79
4.8
1.8
68.50
55.41
%
—
8
48
22
300
0.71
0.77
1.3
1.4
—
—
—
0
0
22
158
1.42
0.77
12.2
6.2
25.88
25.23
mmol/l
0.41
22
158
6
34
1.78
0.76
1.0
1.1
—
—
—
0
0
10
59
1.72
0.76
1.0
1.3
—
—
—
0
0
26
344
0.73
0.76
1.7
1.9
—
—
—
0
0
12
75
1.62
0.76
1.8
2.7
—
—
—
0
0
7
38
1.86
0.74
2.4
1.7
574.20
102.50
u/ml
—
7
38
5
25
2.02
0.73
1.2
1.2
—
—
—
0
0
5
26
1.94
0.71
1.2
2.1
—
—
—
0
0
300
2934
1.42
0.67
30.4
11.3
24.64
24.09
u/l
0.31
300
2857
249
2385
1.21
0.67
42.4
17.3
14.12
13.51
%
7.83
249
2364
5
28
1.80
0.66
1.6
1.8
88.70
90.07
%
—
5
28
136
1243
1.16
0.65
2.1
1.9
1.39
1.36
mmol/l
0.13
120
1063
269
2599
1.23
0.64
6.2
5.9
37.84
38.46
mmol/mol
0.65
261
2457
17
121
1.43
0.63
2.5
1.9
—
—
—
0
0
12
175
0.67
0.62
1.6
1.5
1149.88
977.54
mu/l
0.27
12
142
0
20
0.00
0.60
0.0
1.0
—
0.04
—
0
5
0
22
0.00
0.59
0.0
1.0
—
0.25
—
0
8
0
22
0.00
0.59
0.0
12.9
—
0.71
—
0
22
8
54
1.49
0.57
2.3
2.4
—
—
—
0
0
41
341
1.23
0.56
1.4
1.3
—
—
—
0
0
6
37
1.63
0.56
2.0
1.1
—
—
nmol/l
—
0
0
17
126
1.37
0.53
2.1
2.4
—
—
—
0
0
12
168
0.70
0.52
1.2
1.1
—
—
—
0
0
282
2755
1.21
0.47
5.6
5.0
4.42
4.79
mmol/l
8.48
271
2587
16
121
1.34
0.45
1.0
1.1
1.62
1.60
g/l
0.10
16
121
281
2748
1.20
0.43
5.5
4.9
1.49
1.55
mmol/l
1.24
269
2568
5
31
1.62
0.43
1.4
1.8
12.40
23.37
ng/l
—
5
31
0
17
0.00
0.41
0.0
1.6
—
—
—
0
0
0
17
0.00
0.41
0.0
1.8
—
—
—
0
0
273
2668
1.17
0.39
5.2
4.8
5.39
5.78
mmol/l
8.89
265
2479
16
124
1.31
0.39
1.0
1.1
0.83
0.88
g/l
0.33
16
124
9
67
1.35
0.38
5.6
5.9
1.37
1.10
mmol/l
—
9
59
20
165
1.23
0.32
1.1
1.1
—
—
—
0
0
283
2785
1.15
0.29
6.1
5.6
2.51
2.79
mmol/l
7.69
272
2604
23
269
0.84
0.29
1.4
1.8
3.15
3.43
mmol/l
0.52
14
199
42
378
1.13
0.26
1.3
1.3
—
—
—
0
0
31
349
0.88
0.25
1.5
1.7
—
—
—
0
0
6
82
0.73
0.24
1.2
1.3
—
—
—
0
0
5
40
1.25
0.22
1.2
1.1
—
—
—
0
0
10
124
0.80
0.22
1.0
1.9
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
0.46
—
0
5
0
13
0.00
0.21
0.0
2.3
—
—
—
0
0
0
13
0.00
0.21
0.0
2.2
—
68.54
—
0
13
0
14
0.00
0.20
0.0
1.0
—
0.24
—
0
8
9
114
0.78
0.20
1.8
1.3
—
—
—
0
0
27
241
1.13
0.20
9.0
3.5
—
—
—
0
0
7
86
0.81
0.14
45.6
6.4
—
—
—
0
0
80
831
0.95
0.12
1.6
1.5
—
—
—
0
0
26
240
1.09
0.11
2.0
2.9
43.40
43.02
u/ml
0.01
26
229
12
136
0.88
0.11
1.6
1.4
—
—
—
0
0
26
280
0.92
0.11
1.3
1.3
105.30
171.23
u/ml
—
9
129
11
96
1.15
0.10
2.6
2.2
11.04
13.01
nmol/l
0.24
11
90
12
135
0.88
0.10
1.5
1.4
—
—
—
0
0
37
384
0.96
0.05
1.6
1.5
—
—
—
0
0
15
161
0.93
0.05
1.0
1.1
—
—
—
0
0
16
150
1.07
0.04
1.6
2.2
9790.26
3738.15
u/l
—
7
58
12
129
0.93
0.03
1.5
1.4
—
—
—
0
0
10
107
0.93
0.02
1.6
1.4
—
—
—
0
0
13
136
0.95
0.00
1.5
1.4
—
—
—
0
0
13
132
0.98
0.00
2.2
3.0
0.84
0.77
ug/l
—
6
73
287
2868
1.01
0.00
26.3
12.6
—
—
—
0
0
13
135
0.96
0.00
1.5
1.4
—
—
—
0
0
13
125
1.04
0.00
1.5
1.4
72.38
195.78
pmol/l
0.76
13
120
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
0.03
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.8
—
6.96
—
0
5
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
1.19
—
0
8
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
9
98
0.92
-0.00
1.6
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
51.20
—
0
5
0
5
0.00
-0.00
0.0
1.6
—
60.60
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
1.59
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.8
—
—
—
0
0
7
76
0.92
-0.00
2.4
4.0
3.74
3.92
mmol/l
—
7
76
0
5
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
17.11
—
0
7
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint SLE_OTH and mortality.

Females

Parameter HR [95% CI] p-value
SLE_OTH 2.654 [2.26, 3.11] < 0.001
Birth year 0.994 [0.99, 1.0] 0.168

During the follow-up period (1.1.1998 — 31.12.2019), 283 out of 1188 females with SLE_OTH died.

Males

Parameter HR [95% CI] p-value
SLE_OTH 2.679 [1.67, 4.29] < 0.001
Birth year 0.988 [0.98, 1.0] 0.01

During the follow-up period (1.1.1998 — 31.12.2019), 58 out of 186 males with SLE_OTH died.

Mortality risk

Mortality risk for people of age

years, who have SLE_OTH.

N-year risk Females Males
1 0.202% 0.566%
5 1.436% 2.969%
10 3.668% 7.89%
15 7.028% 14.305%
20 12.148% 23.574%

Relationships between endpoints

Index endpoint: SLE_OTH – Other forms of systemic lupus erythematosus

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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