Other disorders of peripheral nervous system

G6_PERIPHOTH

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G64
  • Cause of death: ICD-10 G64

2 out of 7 registries used, show all original rules.

262

4. Check minimum number of events

None

262

5. Include endpoints

None

262

6. Filter based on genotype QC (FinnGen only)

237

Control definitions (FinnGen only)

Control exclude
G6_POLYNEU

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G60-G64
Name in latin
Aliae morbositates systematis nervosi peripherici

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1252 584 661
Only index persons 1109 536 573
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.02
Only index persons 0.02 0.02 0.02
Median age at first event (years)
Whole population 59.48 59.38 59.73
Only index persons 57.53 58.02 57.07

-FinnGen-

Key figures

All Female Male
Number of individuals 237 128 109
Unadjusted period prevalence (%) 0.05 0.05 0.05
Median age at first event (years) 59.78 57.65 62.28

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
245
Matched controls
2450
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G64
ICD-10 Finland
Other disorders of peripheral nervous system
+∞
307.7
244
*
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
90.1
51.6
56
8
N03AX12
ATC
[U] gabapentin; oral
5.7
37.1
96
249
N03AX16
ATC
[U] pregabalin
4.8
32.2
110
354
N06AX21
ATC
duloxetine; oral
4.8
22.9
63
166
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
5.4
22.0
50
112
G62.8
ICD-10 Finland
Other specified polyneuropathies
216.8
19.9
20
*
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
5.9
18.3
36
70
R20.2
ICD-10 Finland
Paraesthesia of skin
5.2
17.5
40
89
TAB00
NOMESCO Finland
Lumbar puncture
5.4
15.2
32
66
N02BF02
ATC
pregabalin; oral
5.1
15.0
34
75
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
5.2
13.2
29
62
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.7
13.1
117
618
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.6
12.8
49
160
L28
ICPC
Limited function/disability (L)
3.0
12.8
72
298
N02BF01
ATC
gabapentin; oral
3.5
12.3
48
159
N03AE01
ATC
clonazepam; systemic
4.9
12.0
28
63
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.6
10.9
95
487
R52.2
ICD-10 Finland
Other chronic pain
5.4
10.7
22
44
M79.6
ICD-10 Finland
Pain in limb
2.4
10.5
135
822
N02AX02
ATC
tramadol; systemic, rectal
2.4
10.2
131
796
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.6
9.7
34
104
N06AX11
ATC
mirtazapine; oral
2.4
9.7
106
596
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
10.7
9.2
17
17
L12
ICPC
Hand/finger symptom/complaint
2.6
8.8
59
263
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.2
8.5
37
130
AA1AD
NOMESCO Finland
CT of head and brain
2.3
8.4
92
511
G61.8
ICD-10 Finland
Other inflammatory polyneuropathies
+∞
8.4
8
*
R42
ICD-10 Finland
Dizziness and giddiness
2.4
8.1
73
372
S01
ICPC
Pain/tenderness of skin
4.5
8.1
20
47
A01
ICPC
Pain general/multiple sites
2.9
7.7
40
155
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.5
7.7
54
245
R07.4
ICD-10 Finland
Chest pain, unspecified
2.2
7.6
89
506
J45.9
ICD-10 Finland
Asthma, unspecified
2.4
7.5
62
304
H02AB06
ATC
prednisolone; systemic
2.1
7.5
135
904
G60.0
ICD-10 Finland
Hereditary motor and sensory neuropathy
+∞
7.3
7
*
N06AA09
ATC
amitriptyline; systemic
3.0
7.2
34
125
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.6
7.2
48
212
L17
ICPC
Foot/toe symptom/complaint
2.1
7.1
91
533
M54.5
ICD-10 Finland
Low back pain
2.1
7.0
103
634
Z01.8
ICD-10 Finland
Other specified special examinations
2.3
6.9
65
335
N99
ICPC
Neurological disease other
12.7
6.6
11
9
ACC51
NOMESCO Finland
Release of median nerve
3.3
6.6
26
86
R52.9
ICD-10 Finland
Pain, unspecified
2.7
6.6
37
150
A28
ICPC
Limited function/disability NOS
2.3
6.5
58
292
R4110
NOMESCO Finland
Physiotherapy
2.1
6.4
81
468
N03AX09
ATC
lamotrigine; oral
4.1
6.4
18
47
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
6.4
133
920
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
6.3
75
424
G57.3
ICD-10 Finland
Lesion of lateral popliteal nerve
8.0
6.2
13
17
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.9
6.2
30
112
C01DA14
ATC
isosorbide mononitrate; oral
2.4
6.1
48
229
A04
ICPC
Weakness/tiredness general
2.4
6.0
45
209

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
61
143
5.35
25.66
3.5
2.7
—
—
—
0
0
53
115
5.60
24.23
1.5
1.3
—
29.26
—
0
10
27
42
7.10
17.03
1.2
1.3
—
—
—
0
0
29
49
6.58
16.94
1.2
1.1
1.50
7.22
e6/l
1.00
18
36
29
51
6.32
16.28
1.2
1.2
4.68
132.85
e6/l
0.59
19
41
162
956
3.05
15.41
2.6
2.1
91.01
95.82
pmol/l
0.65
88
498
128
701
2.73
13.43
2.8
2.0
194.51
197.31
u/l
0.02
120
661
158
980
2.72
12.64
6.8
4.6
36.15
35.73
g/l
0.42
148
920
119
681
2.45
10.72
4.8
4.2
7.40
7.40
ph
0.71
85
485
65
279
2.81
10.60
1.4
1.4
413.33
627.40
titre
—
9
73
154
998
2.46
10.40
11.5
6.5
1.22
1.21
mmol/l
0.23
146
920
123
727
2.39
10.16
7.2
5.4
—
—
—
0
0
16
12
14.16
9.81
1.3
1.1
0.46
0.48
ratio
—
9
5
162
1099
2.40
9.51
8.6
7.5
1.22
1.21
mmol/l
0.59
143
952
165
1133
2.40
9.35
7.5
6.1
1.72
1.93
e9/l
1.25
146
996
162
1108
2.36
9.20
7.6
6.0
0.57
0.58
e9/l
0.12
141
942
176
1248
2.46
9.19
11.7
10.6
4.25
4.15
e9/l
0.24
158
1086
162
1112
2.35
9.06
7.6
6.0
0.04
0.04
e9/l
0.50
141
944
98
549
2.31
8.89
2.6
2.1
2.28
3.11
mg/l
4.23
86
478
74
372
2.42
8.55
4.1
3.2
0.80
0.82
mmol/l
0.70
67
350
109
657
2.19
8.11
2.1
1.7
20.20
21.07
nmol/l
0.25
96
551
57
260
2.55
8.07
1.8
3.0
1.72
1.87
%
0.71
49
240
123
780
2.16
8.01
4.4
3.4
2.35
2.36
mmol/l
0.19
114
704
15
16
9.90
7.90
1.1
1.1
—
—
—
0
0
162
1150
2.21
7.82
7.9
6.5
0.18
0.19
e9/l
0.26
143
1000
89
502
2.21
7.75
1.3
1.3
3.83
1.71
u/ml
0.39
15
142
186
1405
2.34
7.59
6.0
4.7
—
350.91
—
0
22
47
203
2.63
7.40
1.9
3.1
62.51
73.65
e9/l
2.21
35
158
23
65
3.80
7.34
5.9
4.2
23.23
1.68
ratio
0.59
13
37
146
1017
2.08
7.13
8.3
5.9
2.74
2.83
%
0.24
140
949
23
67
3.68
7.03
1.1
1.1
—
—
—
0
0
140
969
2.04
6.86
4.0
3.0
141.50
130.51
ug/l
0.23
132
901
27
90
3.25
6.74
1.4
1.8
5.25
4.82
iu/ml
—
10
23
145
1022
2.03
6.69
8.5
6.0
9.12
8.76
%
0.83
140
959
133
912
2.00
6.60
3.5
3.6
6.17
6.21
ph
0.18
79
515
28
97
3.13
6.56
1.7
2.3
1.49
1.53
g/l
0.07
22
87
17
42
4.27
6.47
4.1
6.6
—
—
—
0
0
40
172
2.58
6.32
1.1
1.2
—
—
—
0
0
185
1444
2.15
6.22
4.3
3.3
57.10
47.46
u/l
0.53
177
1362
187
1469
2.15
6.13
6.1
4.7
—
2.43
—
0
6
67
372
2.10
5.85
1.6
1.7
1061.05
1207.05
nmol/l
0.62
56
280
14
24
6.12
5.62
1.4
1.1
—
—
—
0
0
83
509
1.95
5.46
3.9
4.2
1.02
1.02
kg/l
0.08
59
331
73
430
1.99
5.38
1.9
1.4
2.23
2.59
g/l
0.58
43
253
16
45
3.73
5.14
1.6
1.4
—
—
—
0
0
155
1177
1.86
5.12
4.5
4.0
0.00
0.02
estimate
0.50
28
215
43
212
2.25
5.01
2.8
2.6
75.31
29.94
u/l
0.45
35
176
152
1153
1.84
4.98
4.4
3.9
0.00
0.00
estimate
-0.00
29
231
12
20
6.25
4.98
1.9
4.0
—
—
—
0
0
95
626
1.85
4.93
5.6
4.2
—
—
—
0
0
69
411
1.94
4.87
1.5
1.3
22.56
29.46
iu/ml
0.31
21
121
117
824
1.80
4.87
5.3
3.9
25.21
94.94
e6/l
2.05
92
588
79
495
1.88
4.78
1.8
1.7
0.93
1.26
mg/l
0.90
59
398
94
625
1.82
4.69
4.3
3.0
0.49
0.34
e6/l
0.45
77
446
73
452
1.88
4.56
1.7
1.9
409.86
439.33
pmol/l
0.51
64
377
8
8
10.28
4.55
1.0
1.0
118.62
147.75
nmol/l
—
8
8
105
727
1.78
4.55
4.5
3.2
72.78
135.30
e6/l
0.26
86
556
79
504
1.84
4.48
2.8
2.6
6.22
4.24
e6/l
0.62
74
455
59
344
1.94
4.40
4.2
3.1
3.31
2.42
e6/l
0.25
29
169
59
348
1.92
4.24
1.8
1.8
—
—
—
0
0
150
1167
1.74
4.18
4.4
4.0
0.00
0.00
estimate
-0.00
29
238
24
99
2.58
4.12
2.1
1.4
0.35
0.36
mg/l
0.04
15
43
139
1062
1.71
4.11
19.2
13.2
1.31
1.24
inr
0.63
115
864
60
369
1.83
3.76
1.4
1.3
1.21
9.79
u/ml
1.59
21
132
12
30
4.15
3.65
3.1
2.4
—
—
—
0
0
10
23
4.49
3.34
1.4
2.7
0.57
1.42
g/24h
—
5
16
218
1946
2.09
3.33
6.3
5.5
1.65
1.95
mu/l
4.01
208
1793
190
1627
1.75
3.29
4.5
4.4
14.99
14.92
pmol/l
0.14
178
1482
67
443
1.71
3.24
7.3
3.7
362.48
299.86
ng/l
0.11
52
352
36
196
1.98
3.24
5.8
6.7
8.83
9.42
mmol/l
0.21
36
187
11
29
3.92
3.23
1.5
1.4
—
—
—
0
0
11
29
3.92
3.23
1.4
1.3
—
—
—
0
0
46
273
1.84
3.21
13.3
8.6
1.36
0.87
mmol/l
0.37
39
228
46
274
1.84
3.17
13.7
8.6
7.43
7.42
ph
0.51
27
164
16
62
2.69
3.11
1.6
1.4
—
—
—
0
0
6
8
7.65
3.07
1.8
1.8
—
—
—
0
0
7
12
5.97
3.04
1.6
1.2
1764.29
1417.92
ml
—
7
12
68
460
1.66
3.00
3.8
2.7
2.47
2.45
mmol/l
0.34
63
416
100
744
1.58
3.00
3.2
2.5
49.33
61.22
u/l
1.24
95
693
91
667
1.58
2.89
3.4
3.1
—
—
—
0
0
58
834
0.60
2.89
3.2
3.4
—
—
—
0
0
47
293
1.75
2.78
1.7
1.6
—
—
—
0
0
16
66
2.52
2.77
1.6
1.3
—
—
—
0
0
16
66
2.52
2.77
1.6
1.3
—
—
—
0
0
16
66
2.52
2.77
1.6
1.3
—
—
—
0
0
227
2085
2.21
2.76
27.0
16.1
22.65
23.23
mg/l
0.12
205
1724
45
279
1.75
2.71
1.2
1.3
—
—
—
0
0
114
889
1.53
2.70
3.7
3.9
0.00
0.00
estimate
-0.00
24
191
43
264
1.76
2.68
2.0
1.5
—
—
—
0
0
13
49
2.75
2.67
1.5
1.4
—
—
—
0
0
80
580
1.56
2.62
2.3
3.1
331.40
346.98
umol/l
0.79
72
504
16
68
2.45
2.61
1.6
1.3
—
—
—
0
0
7
15
4.77
2.61
1.4
2.1
43.67
33.15
%
—
7
15
113
885
1.51
2.60
5.3
4.0
30.77
37.28
ng/l
0.46
82
641
49
315
1.69
2.60
12.4
7.4
104.96
104.11
mmol/l
0.88
49
315
6
11
5.56
2.56
1.0
1.4
—
—
—
0
0
128
1032
1.50
2.55
3.4
2.8
—
—
estimate
—
0
0
63
435
1.60
2.53
2.5
3.0
488.70
533.51
mosm/kgh2o
0.89
57
377
8
21
3.90
2.48
1.5
1.5
19.13
35.65
ng/l
—
8
21
38
232
1.76
2.42
1.7
1.6
—
—
—
0
0
6
12
5.09
2.41
1.2
1.3
77.50
160.72
mmol/24h
—
6
12
5
8
6.35
2.38
1.4
1.1
—
—
—
0
0
15
66
2.36
2.29
1.7
1.4
281.50
314.55
ug/g
—
8
37
42
269
1.68
2.26
4.2
4.7
22.43
23.16
ug/l
0.01
34
222
26
144
1.90
2.25
16.4
4.9
—
—
—
0
0
9
29
3.18
2.25
1.1
1.6
—
—
—
0
0
41
262
1.68
2.22
2.2
1.7
—
—
—
0
0
220
2032
1.81
2.12
5.7
5.3
6.11
5.98
mmol/l
0.56
211
1870
86
659
1.47
2.11
9.4
6.8
—
—
—
0
0
94
734
1.46
2.09
3.9
3.5
73.52
49.56
mg/l
0.49
66
473
7
22
3.24
1.89
1.4
3.9
320.86
795.05
mg
—
7
22
17
87
2.03
1.85
2.5
2.5
—
—
—
0
0
8
29
2.82
1.81
1.3
1.2
—
—
—
0
0
116
961
1.39
1.79
12.5
11.5
0.00
0.00
e9/l
0.59
89
777
36
237
1.61
1.75
2.3
3.6
5.98
5.71
kpa
0.87
36
231
36
237
1.61
1.75
2.7
3.7
7.38
7.39
ph
0.36
18
137
95
765
1.39
1.72
4.0
3.4
7.61
7.75
mmol/l
0.11
85
635
40
272
1.56
1.71
3.3
2.1
103.40
111.94
ug/g
0.11
30
220
23
135
1.78
1.69
2.0
2.5
0.64
0.62
%
0.10
23
135
92
739
1.39
1.69
3.1
2.4
—
—
—
0
0
10
40
2.56
1.68
1.7
1.8
—
—
—
0
0
40
278
1.52
1.56
2.8
3.0
4.13
5.22
e9/l
0.60
34
240
93
757
1.37
1.55
4.7
4.1
11.81
8.01
mg/mmol
0.37
62
476
11
51
2.21
1.53
1.7
1.9
72.49
59.80
%
1.42
11
51
9
37
2.49
1.49
1.1
1.2
—
—
—
0
0
28
181
1.62
1.48
4.4
2.1
6.03
6.12
ph
0.21
20
115
29
190
1.60
1.45
6.1
9.7
—
—
—
0
0
41
291
1.49
1.45
1.2
1.3
—
—
—
0
0
81
654
1.36
1.40
4.1
4.1
0.00
0.00
estimate
-0.00
28
217
9
42
2.19
1.35
2.2
1.6
—
—
—
0
0
32
220
1.52
1.32
1.6
1.6
—
—
—
0
0
10
48
2.13
1.29
2.8
2.5
—
—
—
0
0
11
55
2.05
1.29
1.0
1.2
—
—
—
0
0
22
139
1.64
1.28
2.1
2.5
1.53
1.19
%
0.68
22
139
8
35
2.33
1.28
1.0
1.4
—
—
—
0
0
11
201
0.53
1.28
1.4
1.4
—
—
—
0
0
101
854
1.31
1.26
2.1
2.2
—
—
—
0
0
44
329
1.41
1.20
3.5
2.0
—
—
—
0
0
23
150
1.59
1.19
1.4
1.5
—
—
—
0
0
5
20
2.53
1.15
3.4
2.5
—
—
—
0
0
5
20
2.53
1.15
2.0
2.0
—
—
—
0
0
23
153
1.56
1.11
1.5
1.9
—
—
—
0
0
5
21
2.41
1.09
2.0
1.7
12.52
10.76
%
—
5
21
221
2108
1.49
1.06
6.3
6.1
2.55
2.69
mmol/l
1.71
211
1956
7
33
2.15
1.06
1.1
1.5
—
—
—
0
0
7
33
2.15
1.06
1.1
1.5
—
—
—
0
0
7
33
2.15
1.06
1.1
1.5
—
—
—
0
0
7
33
2.15
1.06
1.1
1.5
—
—
—
0
0
78
650
1.29
1.06
2.9
3.4
0.04
0.01
estimate
0.31
26
185
21
139
1.56
1.04
1.2
1.3
—
—
—
0
0
5
22
2.30
1.04
1.2
1.4
—
—
—
0
0
18
115
1.61
1.03
5.1
3.3
—
—
—
0
0
20
132
1.56
1.00
1.5
1.3
246.40
161.34
u/ml
—
5
53
5
23
2.20
0.98
1.4
1.3
—
—
—
0
0
18
117
1.58
0.97
1.1
1.4
—
—
—
0
0
17
109
1.60
0.96
2.2
2.5
—
—
—
0
0
11
62
1.81
0.96
1.2
1.1
—
—
—
0
0
23
162
1.46
0.88
5.0
3.4
5.05
5.09
kpa
0.16
23
157
217
2080
1.38
0.83
5.3
5.4
4.39
4.61
mmol/l
2.77
207
1933
60
498
1.27
0.83
4.9
5.3
—
—
—
0
0
15
97
1.58
0.83
3.5
1.9
—
—
—
0
0
0
24
0.00
0.79
0.0
3.4
—
—
—
0
0
216
2074
1.35
0.77
5.2
5.3
1.42
1.46
mmol/l
0.66
203
1921
210
2011
1.31
0.74
7.5
6.7
39.89
39.70
mmol/mol
0.10
205
1891
34
266
1.32
0.73
1.4
1.3
—
—
—
0
0
184
1736
1.24
0.73
32.9
20.5
13.59
13.68
%
0.49
184
1723
5
25
2.02
0.73
1.2
1.3
—
—
—
0
0
16
109
1.50
0.73
1.3
1.3
—
—
—
0
0
223
2156
1.38
0.71
22.2
14.5
—
—
—
0
0
22
161
1.40
0.71
2.5
3.8
72.54
82.44
ng/l
0.34
16
137
14
202
0.67
0.69
1.1
1.4
—
—
—
0
0
7
42
1.69
0.69
1.1
1.3
—
—
—
0
0
7
44
1.61
0.65
1.7
2.2
—
85.35
—
0
11
5
30
1.68
0.62
1.8
1.7
33.80
33.03
pg
—
5
30
27
211
1.31
0.60
1.3
1.4
—
—
—
0
0
0
21
0.00
0.60
0.0
2.6
—
8.55
—
0
15
12
82
1.49
0.55
2.0
2.3
1.57
1.53
mg/l
0.06
12
69
12
83
1.47
0.53
1.1
1.1
—
—
—
0
0
9
65
1.40
0.51
1.6
1.8
237.33
335.34
mu/l
—
9
59
22
172
1.31
0.50
3.6
3.7
—
—
—
0
0
24
193
1.27
0.45
4.2
4.9
0.86
1.01
%
—
7
71
5
32
1.57
0.42
1.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
6.0
—
7.44
—
0
15
0
15
0.00
0.41
0.0
5.9
—
17.15
—
0
15
0
17
0.00
0.41
0.0
16.0
—
1023.88
—
0
17
22
178
1.26
0.40
3.8
5.0
1.00
0.55
%
—
6
61
25
206
1.24
0.40
1.4
1.4
—
—
—
0
0
204
1982
1.17
0.38
4.8
4.5
1.25
1.29
mmol/l
0.59
194
1823
5
36
1.40
0.38
1.0
1.1
—
—
—
0
0
66
599
1.14
0.36
1.3
1.4
—
—
—
0
0
6
41
1.47
0.36
1.7
2.0
7.83
7.69
pmol/l
—
6
41
22
183
1.22
0.33
4.0
5.5
0.00
0.19
%
—
5
53
99
929
1.11
0.31
1.8
2.0
1.47
1.38
mmol/l
0.60
89
764
7
55
1.28
0.30
1.1
1.3
—
—
—
0
0
50
452
1.13
0.30
2.9
3.1
0.67
0.77
ug/l
0.37
41
280
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
84.00
—
0
11
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
9
113
0.79
0.20
5.7
2.9
11.44
45.56
u/ml
—
9
108
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
80
760
1.08
0.19
5.6
5.4
2.25
2.62
ug/l
0.20
74
675
5
68
0.73
0.17
1.0
1.2
—
—
—
0
0
5
44
1.14
0.10
8.8
3.8
66.00
33.15
u/ml
—
5
44
5
45
1.11
0.10
1.2
1.2
0.73
0.96
nmol/l
—
5
38
7
64
1.10
0.08
1.3
1.7
260.29
236.88
pmol/l
—
7
58
9
84
1.07
0.07
1.4
1.6
—
—
—
0
0
11
112
0.98
0.00
1.3
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
7
79
0.88
-0.00
9.1
12.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
60
1.00
-0.00
1.2
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
17.32
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
1453.14
—
0
7
0
8
0.00
-0.00
0.0
1.4
—
11.43
—
0
8
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint G6_PERIPHOTH and mortality.

Females

Parameter HR [95% CI] p-value
G6_PERIPHOTH 1.811 [1.42, 2.32] < 0.001
Birth year 0.991 [0.98, 1.0] 0.162

During the follow-up period (1.1.1998 — 31.12.2019), 143 out of 508 females with G6_PERIPHOTH died.

Males

Parameter HR [95% CI] p-value
G6_PERIPHOTH 2.226 [1.7, 2.91] < 0.001
Birth year 0.984 [0.97, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 185 out of 563 males with G6_PERIPHOTH died.

Mortality risk

Mortality risk for people of age

years, who have G6_PERIPHOTH.

N-year risk Females Males
1 0.178% 0.322%
5 0.962% 2.451%
10 2.551% 6.395%
15 4.571% 12.048%
20 7.489% 19.046%

Relationships between endpoints

Index endpoint: G6_PERIPHOTH – Other disorders of peripheral nervous system

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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