Respiratory disorders in diseases classified elsewhere

RESP_ILL_DIS_CLASS_ELSEWHERE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 J99*
  • Cause of death: ICD-10 J99*

2 out of 7 registries used, show all original rules.

547

4. Check minimum number of events

None

547

5. Include endpoints

None

547

6. Filter based on genotype QC (FinnGen only)

506

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2217 1242 966
Only index persons 1831 1044 787
Unadjusted period prevalence (%)
Whole population 0.03 0.04 0.03
Only index persons 0.03 0.04 0.03
Median age at first event (years)
Whole population 65.05 65.35 64.68
Only index persons 64.02 64.19 63.78

-FinnGen-

Key figures

All Female Male
Number of individuals 506 301 205
Unadjusted period prevalence (%) 0.10 0.11 0.09
Median age at first event (years) 63.55 62.40 65.26

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
520
Matched controls
5200
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
44.0
307.7
394
345
L04AX01
ATC
azathioprine; systemic
48.0
307.7
248
97
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
30.9
305.1
232
132
L04AA06
ATC
mycophenolic acid; systemic
57.6
261.0
152
37
P01BA02
ATC
hydroxychloroquine; oral
16.2
216.0
236
253
J99.1*M31.3
ICD-10 Finland
Respiratory disorders in Wegener's granulomatosis
+∞
193.1
173
*
L04AX03
ATC
methotrexate; systemic
13.4
184.6
228
287
TGC00
NOMESCO Finland
Bronchial lavation
25.9
174.7
130
66
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
15.2
170.3
177
171
M31.3
ICD-10 Finland
Wegener granulomatosis
274.9
158.9
155
8
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
28.3
148.8
105
46
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
12.4
148.0
177
208
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
22.4
146.7
115
65
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
25.5
142.8
105
51
UGC12
NOMESCO Finland
Flexible bronchoscopy
11.1
136.8
178
233
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
13.0
135.2
150
157
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
46.4
131.9
79
20
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
9.7
126.9
404
1374
GD1AD
NOMESCO Finland
Thorax CT examination
11.7
126.2
152
178
H02AB06
ATC
prednisolone; systemic
16.9
121.8
473
1944
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
8.8
118.1
192
325
J99.0*M05.1
ICD-10 Finland
Rheumatoid lung disease
+∞
113.8
105
*
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
20.6
113.6
91
53
M05BA04
ATC
alendronic acid; oral
9.1
112.4
171
267
L01BA01
ATC
methotrexate; systemic
16.7
110.4
99
72
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
9.6
100.4
138
189
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
9.5
88.7
119
157
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
31.0
86.8
58
21
GD1AA
NOMESCO Finland
Thorax X-ray examination
7.5
82.9
428
1986
J99.1
ICD-10 Finland
Respiratory disorders in other diffuse connective tissue disorders
+∞
78.1
73
*
XG410
NOMESCO Finland
Flow-volume spirometry
10.3
73.4
89
102
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
9.6
72.8
94
117
J18.9
ICD-10 Finland
Pneumonia, unspecified
4.8
69.3
266
933
ZX120
NOMESCO Finland
Intravenous
6.3
68.2
139
285
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
11.2
66.7
75
77
J99.1*M35.0
ICD-10 Finland
Respiratory disorders in sicca syndrome [Sjögren]
+∞
66.1
62
*
N08.5*M31.3
ICD-10 Finland
Glomerular disorders in Wegener's granulomatosis
+∞
63.9
60
*
L88
ICPC
Rheumatoid/seropositive arthritis
9.6
63.8
81
98
DHA10
NOMESCO Finland
Biopsy of cavity of nose
25.2
61.5
44
19
A07EC01
ATC
sulfasalazine; oral, rectal
6.5
60.5
114
215
L04AA13
ATC
[U] leflunomide
13.2
60.2
60
51
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
10.4
60.0
71
78
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
20.8
56.8
44
23
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
11.1
52.3
58
58
J99.0
ICD-10 Finland
Rheumatoid lung disease
+∞
52.0
49
*
L04AD01
ATC
ciclosporin; systemic
17.1
51.8
44
28
R50.9
ICD-10 Finland
Fever, unspecified
4.4
49.4
162
486
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
6.6
47.2
84
148
J99.1*M33.2
ICD-10 Finland
Respiratory disorders in polymyositis
+∞
44.4
42
*
J01MA14
ATC
moxifloxacin; systemic
4.9
43.3
110
268
H02AB07
ATC
prednisone; oral
4.1
41.3
140
425
M31.1
ICD-10 Finland
Thrombotic microangiopathy
+∞
41.2
39
*
J99.1*M34.8
ICD-10 Finland
Respiratory disorders in systemic: sclerosis
+∞
40.1
38
*
M33.2
ICD-10 Finland
Polymyositis
111.1
38.3
41
*
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
4.4
37.8
112
306
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
9.4
37.2
46
53
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
9.1
37.0
47
56
J99.1*M32.1
ICD-10 Finland
Respiratory disorders in systemic: lupus erythematosus
+∞
36.9
35
*
M05.1
ICD-10 Finland
Rheumatoid lung disease
382.6
36.5
36
*
1XC02, ,
NOMESCO Finland
51.9
36.3
43
9
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
4.7
36.1
94
232
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
4.7
36.0
95
237
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
7.7
35.4
52
74
J01MA12
ATC
levofloxacin; systemic
3.4
34.1
162
609
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
5.3
33.9
74
157
R06.0
ICD-10 Finland
Dyspnoea
3.1
33.7
229
1062
UDH02
NOMESCO Finland
Rhinopharyngoscopy
4.8
32.4
82
197
L01AA01
ATC
cyclophosphamide; systemic
74.7
31.3
35
5
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.5
29.1
121
414
M33.9
ICD-10 Finland
Dermatopolymyositis, unspecified
158.8
29.0
30
*
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
6.3
28.9
51
88
NH3EA
NOMESCO Finland
Feet X-ray examination with load
9.8
28.6
34
37
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
28.3
27.5
37
14
TPH04
NOMESCO Finland
Cathetrisation of vein
2.9
26.9
177
789
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
9.2
26.6
33
38
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.8
25.9
196
937
J99.1*M33.9
ICD-10 Finland
Respiratory disorders in dermatopolymyositis
+∞
25.2
24
*
J96.1
ICD-10 Finland
Chronic respiratory failure
7.3
24.5
37
54
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
7.7
24.5
35
48
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
8.6
23.7
31
38
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
10.1
23.4
27
28
C03CA01
ATC
furosemide; systemic
2.5
23.0
215
1127
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.3
22.9
99
344
A02BC02
ATC
pantoprazole; systemic
3.0
22.7
416
2982
H02AB04
ATC
methylprednisolone; systemic
3.0
22.7
118
457
M05BA07
ATC
risedronic acid; oral
6.2
22.6
40
69
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.8
22.3
136
575
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.5
21.9
87
286
WZA10
NOMESCO Finland
Extensive medical or dental certificate
9.1
21.7
27
31
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
6.9
21.5
34
52
M34.9
ICD-10 Finland
Systemic sclerosis, unspecified
62.7
21.0
24
*
M33.1
ICD-10 Finland
Other dermatomyositis
80.2
20.8
23
*
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
5.4
20.6
42
83
M13.9
ICD-10 Finland
Arthritis, unspecified
3.7
20.5
72
218
H04.10
ICD-10 Finland
Dry eye syndrome
3.1
20.3
100
374
R03AK08
ATC
formoterol and beclometasone; inhalant
4.5
20.3
52
125
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.3
20.2
84
284
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.3
19.9
284
1767
L04AA01
ATC
[U] ciclosporin
17.3
19.9
31
19
M05BB03
ATC
alendronic acid and colecalciferol; oral
6.8
19.9
32
50
M34.0
ICD-10 Finland
Progressive systemic sclerosis
207.6
19.7
20
*
M35.1
ICD-10 Finland
Other overlap syndromes
32.7
19.4
25
8
ZX108
NOMESCO Finland
Inhalation
23.6
19.3
27
12
M31.9
ICD-10 Finland
Necrotizing vasculopathy, unspecified
196.8
18.7
19
*
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
5.9
18.4
34
61
H65.2
ICD-10 Finland
Chronic serous otitis media
8.2
18.4
25
32
TDM10
NOMESCO Finland
Puncture of maxillary antrum
4.9
18.1
41
89
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
7.0
18.0
28
42
M34.8
ICD-10 Finland
Other forms of systemic sclerosis
+∞
17.8
17
*
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
98.5
17.7
19
*
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
3.4
17.6
68
219
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
43.6
17.4
21
5
R81
ICPC
Pneumonia
4.8
17.3
40
88
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
20.1
17.0
25
13
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.9
16.8
90
351
1AA01, ,
NOMESCO Finland
+∞
16.8
16
*
GX1K5
NOMESCO Finland
Diffusion capacity
21.8
16.1
23
11
H65.3
ICD-10 Finland
Chronic mucoid otitis media
6.4
16.1
27
44
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
15.1
16.0
26
18
KA1AE
NOMESCO Finland
Kidney ultrasound examination
6.0
15.6
28
49
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
5.3
15.5
32
64
C08CA05
ATC
nifedipine; systemic
3.5
15.4
56
173
SPAT1255
SPAT
Intravenous administration of medicine
3.5
15.4
55
168
WZC30
NOMESCO Finland
Teaching
2.4
15.1
120
568
WW200
NOMESCO Finland
Immunization
6.0
15.1
27
47
M05BX04
ATC
denosumab; parenteral
3.3
15.0
61
202
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
15.7
15.0
24
16
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
7.0
15.0
23
34
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
4.6
15.0
36
82
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
6.4
14.8
25
41
J05AB11
ATC
valaciclovir; oral
2.5
14.8
110
505
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.1
14.7
303
2089
XQ841
NOMESCO Finland
Examination of dermatosis with microscope
154.2
14.5
15
*
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
17.6
14.4
22
13
M34.1
ICD-10 Finland
CR(E)ST syndrome
28.1
14.4
19
7
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
15.0
14.2
23
16
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.7
14.1
87
364
J01FF01
ATC
clindamycin; systemic
2.2
14.1
171
964
DM1BD
NOMESCO Finland
Extensive CT of paranasal sinuses and face area
31.0
14.0
18
6
Z01.8
ICD-10 Finland
Other specified special examinations
2.2
13.8
149
801
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.0
13.7
245
1589
J31.0
ICD-10 Finland
Chronic rhinitis
2.9
13.7
69
259
L99
ICPC
Musculoskeletal disease other
5.6
13.7
26
48
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.3
13.6
128
649
NG1DA
NOMESCO Finland
X-ray of knees
6.1
13.6
24
41
M31.0
ICD-10 Finland
Hypersensitivity angiitis
+∞
13.6
13
*
SPAT1229
SPAT
Assessment of need for aid
3.1
13.6
60
209
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
16.8
13.6
21
13
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.3
13.5
127
644
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
13.5
188
1114
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
6.5
13.4
22
35
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
23.2
13.0
18
8
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.2
12.9
127
655
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
5.3
12.8
26
51
R03AC02
ATC
salbutamol; inhalant
2.0
12.8
316
2277
M81.9
ICD-10 Finland
Osteoporosis, unspecified
3.5
12.6
46
142
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
3.2
12.6
53
179
L04AB01
ATC
etanercept; parenteral
10.4
12.6
24
24
M01CB01
ATC
sodium aurothiomalate; parenteral
11.4
12.1
22
20
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
4.0
11.9
35
93
N08.5
ICD-10 Finland
Glomerular disorders in systemic connective tissue disorders
47.8
11.9
14
*
A01AB09
ATC
miconazole; local oral
2.8
11.9
65
255
M60.9
ICD-10 Finland
Myositis, unspecified
19.5
11.7
17
9
M31.8
ICD-10 Finland
Other specified necrotizing vasculopathies
66.5
11.7
13
*
R04.2
ICD-10 Finland
Haemoptysis
4.1
11.6
32
81
J99.8*M45
ICD-10 Finland
Respiratory disorders in ankylosing spondylitis
+∞
11.5
11
*
A07AA02
ATC
nystatin; oral
3.1
11.5
49
167
L04AB04
ATC
adalimumab; parenteral
5.6
11.4
22
41
J34.8
ICD-10 Finland
Other specified disorders of nose and nasal sinuses
9.9
11.3
22
23
R03BB04
ATC
tiotropium bromide; inhalant
2.6
11.3
73
311
B02.9
ICD-10 Finland
Zoster without complication
2.9
11.3
57
214
NJ3BG
NOMESCO Finland
MRI examination of extremities with high intensity magnet
17.5
11.3
17
10
M05
ICD-10 Finland
Seropositive rheumatoid arthritis
14.3
11.0
18
13
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
44.3
11.0
13
*
A02BC01
ATC
omeprazole; systemic
2.0
10.8
166
1003
R03BA08
ATC
ciclesonide; inhalant
2.7
10.8
62
249
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.0
10.8
50
179
GX1D5
NOMESCO Finland
Flow volume spirometry
22.0
10.7
15
7
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
5.4
10.7
21
40
A03
ICPC
Fever
2.2
10.6
102
518
G04BE03
ATC
sildenafil; oral
9.5
10.6
21
23
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.1
10.5
46
159
XF614
NOMESCO Finland
Measurement of pulmonary artery pressure
112.2
10.5
11
*
M31.7
ICD-10 Finland
Microscopic polyangiitis
112.2
10.5
11
*
C02KX04
ATC
macitentan; oral
+∞
10.4
10
*
WW400
NOMESCO Finland
Plasmaferesis
+∞
10.4
10
*
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.7
10.4
59
235
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.0
10.2
145
852
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.0
10.0
47
169
GDA11
NOMESCO Finland
Thoracoscopic biopsy of lung
17.1
9.9
15
9
H26.3
ICD-10 Finland
Drug-induced cataract
12.5
9.9
17
14
M81.4
ICD-10 Finland
Drug-induced osteoporosis
20.5
9.8
14
7
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.0
9.7
45
161
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
2.1
9.7
111
602
M32.0
ICD-10 Finland
Drug-induced systemic lupus erythematosus
56.1
9.7
11
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.5
9.7
65
282
J01AA02
ATC
doxycycline; systemic
2.0
9.6
417
3456
XG466
NOMESCO Finland
Sleep oxymetry
3.9
9.5
28
75
ZXA10
NOMESCO Finland
Bilateral
2.0
9.4
118
661
GX1E5
NOMESCO Finland
Flow volume spirometry and bronchodilation test
12.7
9.4
16
13
4464A
ICD-9 Finland
Polyarteritis nodosa and allied conditions, Wegener's granulomatosis
+∞
9.4
9
*
J01CA04
ATC
amoxicillin; systemic
2.1
9.4
431
3627
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.4
9.3
70
319
XX9XE
NOMESCO Finland
Other ultrasound examination
10.9
9.3
17
16
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.2
9.3
25
62
NF1AA
NOMESCO Finland
Hip X-ray examination
2.5
9.3
64
280
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
9.8
9.3
18
19
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
3.8
9.3
28
76
UJF92
NOMESCO Finland
Capsular endoscopy
5.2
9.2
19
38
M05BA06
ATC
ibandronic acid; systemic
4.7
9.1
21
46
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.0
9.1
123
708
H02AB09
ATC
hydrocortisone; systemic
4.5
8.9
22
51
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.7
8.9
48
186
J47
ICD-10 Finland
Bronchiectasis
4.6
8.9
21
47
C07AB07
ATC
bisoprolol; oral
1.7
8.8
277
2057
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.2
8.7
82
411
TNB11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in shoulder joint
14.3
8.7
14
10
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
3.9
8.7
26
70
71238
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides alia definita
11.8
8.6
15
13
S97
ICPC
Chronic ulcer skin
2.6
8.6
50
202
XPX04
NOMESCO Finland
Angioscopy
28.0
8.5
11
*
XF622
NOMESCO Finland
Measurement of minute volume of heart
28.0
8.5
11
*
N08.5*M31.1
ICD-10 Finland
Glomerular disorders in thrombotic thrombocytopenic purpura
91.5
8.4
9
*
GX2C5
NOMESCO Finland
Short-lasting oximetry
13.0
8.4
14
11
M01CB03
ATC
auranofin; oral
13.0
8.4
14
11
R28
ICPC
Limited function/disability (R)
7.3
8.3
19
27
E0000UV, ,
ATC
1.7
8.3
228
1620
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.8
8.2
160
1029
GD1UN
NOMESCO Finland
Lung circulation SPECT
14.8
8.2
13
9
356
Kela drug reimbursment
Nintedanib and pirfenidone
14.8
8.2
13
9
J05AB01
ATC
aciclovir; systemic
1.9
8.2
132
802
WX892
NOMESCO Finland
Monitored bed care
2.5
8.0
51
215
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
4.4
8.0
20
47
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
6.8
8.0
19
29
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.4
7.9
29
90
R60.9
ICD-10 Finland
Oedema, unspecified
2.8
7.9
41
156
L04AK01
ATC
leflunomide; oral
13.3
7.9
13
10
127
Kela drug reimbursment
Transplant complication
7.1
7.8
18
26
R4180
NOMESCO Finland
Podiatric therapy
7.1
7.8
18
26
NDL52
NOMESCO Finland
Tenosynovectomy of hand
9.6
7.8
15
16
SPAT1104
SPAT
Monitoring of emergency patient
2.7
7.8
42
163
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.7
7.8
253
1871
UJF32
NOMESCO Finland
Coloscopy
1.8
7.7
150
962
Z94.2
ICD-10 Finland
Lung transplant status
45.7
7.7
9
*
WX726
NOMESCO Finland
High-flow oxygen therapy
45.7
7.7
9
*
7100A
ICD-9 Finland
Diffuse diseases of connective tissue, Systemic lupus erythematosus
45.7
7.7
9
*
J01DB01
ATC
cefalexin; oral
2.0
7.7
432
3715
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.0
7.7
100
565
FB1AD
NOMESCO Finland
CT examination of arteria pulmonalis
3.6
7.6
25
72
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
12.1
7.6
13
11
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
7.3
7.5
17
24
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.5
7.5
26
78
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.0
7.5
82
436
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
7.8
7.4
16
21
GDG10
NOMESCO Finland
Bilateral transplantation of lung
81.2
7.4
8
*
M34
ICD-10 Finland
Systemic sclerosis
81.2
7.4
8
*
JN4AD
NOMESCO Finland
Body CT examination
2.1
7.4
77
401
Z3231
NOMESCO Finland
Registered nurse
1.8
7.4
150
973
L95
ICPC
Osteoporosis
2.9
7.4
35
127
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.3
7.4
28
89
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.2
7.3
63
304
GD2SN
NOMESCO Finland
Lung ventilation SPECT
11.1
7.3
13
12
SPAT1249
SPAT
Treatment-related counselling outside office
1.7
7.3
207
1472
L01EX09
ATC
nintedanib; oral
16.0
7.3
11
7
WX002
NOMESCO Finland
Sedation and analgesia
1.9
7.2
112
669
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.7
7.2
40
158
NXL00
NOMESCO Finland
Biopsy of muscle
20.3
7.2
10
5
M95.0
ICD-10 Finland
Acquired deformity of nose
20.3
7.2
10
5
A41.9
ICD-10 Finland
Sepsis, unspecified
3.3
7.1
27
86
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.8
7.1
35
130
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
3.4
7.1
25
76
ZXE00
NOMESCO Finland
One hour or less
1.7
7.0
203
1448
WX882
NOMESCO Finland
High dependency care
4.1
6.9
19
48
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
14.0
6.9
11
8
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.7
6.9
145
948
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
3.1
6.9
28
93
NA1BA
NOMESCO Finland
Cervical spine extensive X-ray examination without contrast
11.1
6.8
12
11
M05BA01
ATC
etidronic acid; systemic
11.1
6.8
12
11
WX202
NOMESCO Finland
Supraclavicular plexus blockade
6.2
6.8
17
28
3AC01, ,
NOMESCO Finland
9.5
6.8
13
14
N02AX02
ATC
tramadol; systemic, rectal
1.6
6.8
228
1683
CCD50
NOMESCO Finland
Dacryocystorhinostomy with insertion of tube
40.6
6.8
8
*
N08.5*M32.1
ICD-10 Finland
Glomerular disorders in systemic lupus erythematosus
40.6
6.8
8
*
GD1BT
NOMESCO Finland
Biopsy of lung with X-ray guidance
40.6
6.8
8
*
M60.8
ICD-10 Finland
Other myositis
40.6
6.8
8
*
M35.3
ICD-10 Finland
Polymyalgia rheumatica
2.8
6.7
33
122
K05.31
ICD-10 Finland
Periodontitis pronounced
2.1
6.7
64
322
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
2.4
6.7
47
208
J45.1
ICD-10 Finland
Nonallergic asthma
2.4
6.7
47
208
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
3.2
6.7
26
84
SBA00
NOMESCO Finland
Microbiological examinations
4.1
6.7
18
45
B37.09
ICD-10 Finland
Unspecified candidal stomatitis
8.0
6.6
14
18
J45.9
ICD-10 Finland
Asthma, unspecified
1.8
6.6
109
662
J93.8
ICD-10 Finland
Other pneumothorax
12.5
6.6
11
9
SPAT1254
SPAT
Administration of medicine
1.9
6.6
83
463
D64.9
ICD-10 Finland
Anaemia, unspecified
2.1
6.6
65
332
S18
ICPC
Laceration/cut
1.6
6.6
256
1956
J01MA02
ATC
ciprofloxacin; systemic
1.6
6.6
203
1466
UDM02
NOMESCO Finland
Sinoscopy
3.7
6.5
20
55
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
6.5
192
1369
TEA00
NOMESCO Finland
Biopsy of lip
7.5
6.4
14
19
M32
ICD-10 Finland
Systemic lupus erythematosus
70.7
6.4
7
*
G73.7*M35.0
ICD-10 Finland
Myopathy in sicca syndrome [Sjögren]
70.7
6.4
7
*
Z2446
NOMESCO Finland
Social worker
2.5
6.4
42
180
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
2.8
6.4
31
114
J12.8
ICD-10 Finland
Other viral pneumonia
8.3
6.4
13
16
JN4CD
NOMESCO Finland
Very extensive body CT
3.0
6.4
27
92
C08CA01
ATC
amlodipine; oral
1.6
6.4
210
1538
R4120
NOMESCO Finland
Occupational therapy
2.4
6.3
43
188
XQ860
NOMESCO Finland
Laser Doppler measurement/scan of capillary perfusion
+∞
6.3
6
*
J990, M058,
ICD-10 Finland
+∞
6.3
6
*
C02KX01
ATC
bosentan; oral
+∞
6.3
6
*
N08.5*M31.7
ICD-10 Finland
Glomerular disease states in microscopic polyangiitis
+∞
6.3
6
*
I27.8
ICD-10 Finland
Other specified pulmonary heart diseases
27.0
6.2
8
*
I27.0
ICD-10 Finland
Primary pulmonary hypertension
27.0
6.2
8
*
M35.8
ICD-10 Finland
Other specified systemic involvement of connective tissue
27.0
6.2
8
*
SAA03
NOMESCO Finland
Extended examination of mouth
1.6
6.2
198
1435
ZXD05
NOMESCO Finland
Urgent procedure
1.7
6.2
155
1059
M45
ICD-10 Finland
Ankylosing spondylitis
3.8
6.1
18
48
I73.0
ICD-10 Finland
Raynaud syndrome
4.2
6.1
16
39
B01AB05
ATC
enoxaparin; parenteral
1.6
6.1
175
1235
Z3226
NOMESCO Finland
Physiotherapist
1.8
6.1
102
622
EL3AE
NOMESCO Finland
Salivary gland ultrasound examination
8.7
6.1
12
14
Z3229
NOMESCO Finland
Other healthcare associate professional
2.2
6.1
51
244
SPAT1262
SPAT
Handing over of treatment supplies
1.8
6.1
94
560
M02.9
ICD-10 Finland
Reactive arthropathy, unspecified
6.1
6.0
15
25

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
242
204
21.32
259.66
12.9
1.5
21.92
14.47
iu/ml
—
110
6
191
173
16.87
192.58
3.1
1.2
—
—
—
0
0
191
212
13.66
167.59
4.4
1.7
14.74
7.32
iu/ml
1.30
73
53
144
139
13.94
136.98
1.9
1.2
50.46
—
u/ml
—
12
0
201
311
9.91
135.09
2.6
1.7
1.11
1.51
g/l
0.83
191
285
275
668
7.62
120.36
2.0
1.4
851.33
502.03
titre
2.46
113
158
135
151
11.72
115.30
1.9
1.3
5.01
2.59
u/ml
0.73
34
19
135
152
11.65
114.74
1.9
1.3
7.28
6.40
u/ml
0.07
56
27
136
160
11.16
111.84
1.9
1.3
25.46
17.82
u/ml
—
18
9
123
127
12.38
110.85
1.8
1.3
30.73
2.24
u/ml
—
24
9
106
89
14.70
108.92
3.1
1.2
207.88
—
titre
—
33
0
138
199
9.08
96.03
1.7
1.3
5.01
2.74
u/ml
—
18
10
69
31
25.51
95.80
1.3
1.1
—
—
—
0
0
73
45
18.71
88.16
1.8
1.4
0.34
0.41
g/l
0.41
53
36
73
45
18.71
88.16
1.8
1.4
2.29
2.86
g/l
1.35
53
36
73
45
18.71
88.16
1.8
1.4
5.99
6.63
g/l
0.62
53
37
74
47
18.19
88.06
1.9
1.3
—
—
—
0
0
87
78
13.19
85.22
2.0
1.8
0.71
0.79
g/l
0.14
64
67
472
2442
11.11
79.83
26.0
6.1
0.65
0.58
e9/l
8.68
463
2096
473
2454
11.26
79.70
26.0
6.1
0.04
0.04
e9/l
1.01
464
2111
98
118
10.00
78.02
1.9
1.2
70.02
41.19
u/ml
0.81
27
15
473
2491
10.94
77.22
26.1
6.2
1.65
1.92
e9/l
4.72
465
2204
78
69
13.12
76.83
1.8
1.3
40.56
116.66
u/ml
—
12
5
369
1585
5.57
75.77
22.6
5.9
—
—
—
0
0
474
2529
10.88
75.41
26.9
6.4
0.18
0.19
e9/l
0.53
465
2214
436
2298
6.55
65.68
26.4
6.2
23.18
27.54
%
16.15
436
2183
474
2715
9.43
64.09
28.6
9.8
4.95
4.11
e9/l
10.02
464
2386
180
492
5.07
63.45
1.4
1.6
—
—
—
0
0
56
39
15.97
63.09
2.3
1.9
1085.08
1172.53
e6/l
0.21
50
34
142
320
5.73
62.58
1.3
1.4
—
—
—
0
0
169
453
5.05
60.72
8.9
4.5
0.72
0.85
%
0.43
88
146
161
428
5.00
58.20
9.1
4.6
0.06
0.14
%
0.87
80
120
198
637
4.40
55.77
1.5
1.6
—
—
—
0
0
304
1340
4.05
54.52
7.0
4.3
—
—
—
0
0
157
430
4.80
54.35
8.8
4.4
0.42
0.51
%
0.33
78
131
63
71
9.96
52.12
2.8
2.9
—
—
—
0
0
47
34
15.10
51.68
2.0
1.2
224.55
90.00
titre
—
11
6
59
66
9.96
49.02
1.9
1.5
—
—
—
0
0
59
66
9.96
49.02
1.9
1.5
—
—
—
0
0
59
66
9.96
49.02
1.9
1.5
—
—
—
0
0
59
66
9.96
49.02
1.9
1.5
—
—
—
0
0
61
73
9.33
48.14
3.4
2.7
—
—
—
0
0
59
69
9.52
47.38
4.7
3.4
4.57
4.73
e9/l
0.15
59
69
426
2525
4.80
46.73
9.2
4.0
0.00
0.00
estimate
-0.00
121
543
428
2551
4.83
46.44
9.3
4.0
11.60
6.29
estimate
0.17
125
557
149
440
4.34
46.10
9.8
4.9
0.01
0.18
%
1.08
69
112
429
2579
4.79
45.54
9.3
4.0
0.00
0.59
estimate
0.52
122
522
237
975
3.63
45.14
2.3
1.6
2.34
2.45
g/l
0.40
195
580
309
1529
3.52
43.36
5.8
3.2
1162.82
1269.54
ng/l
0.28
289
1318
385
2206
3.87
42.37
12.3
6.6
1.21
1.21
mmol/l
0.23
376
2041
364
2015
3.69
42.22
7.8
3.6
6.35
6.22
ph
1.33
178
1155
375
2119
3.76
42.03
4.0
2.6
81.73
78.27
nmol/l
1.67
362
1903
408
2439
4.12
41.86
13.6
7.5
1.22
1.21
mmol/l
0.45
364
2121
175
620
3.75
41.35
5.4
3.1
6.64
5.69
e9/l
0.17
165
542
171
597
3.78
41.29
2.4
1.4
—
—
—
0
0
187
699
3.62
40.62
3.1
2.1
—
—
—
0
0
53
66
8.83
40.40
1.7
1.2
—
—
—
0
0
150
487
3.92
40.17
2.1
2.1
345.92
382.50
nmol/l
0.53
140
449
294
1483
3.26
38.57
7.1
4.2
7.40
7.40
ph
0.13
235
1052
62
100
6.90
37.73
4.7
3.2
60.23
59.10
%
0.21
62
100
325
1772
3.22
36.66
11.7
4.0
39.97
93.62
e6/l
2.21
269
1259
216
933
3.25
36.49
1.5
1.3
101.69
34.11
iu/ml
2.49
112
279
132
420
3.87
36.04
2.2
3.1
65.46
66.65
g/l
0.77
124
392
186
741
3.35
35.86
1.6
1.8
—
—
—
0
0
200
851
3.19
34.29
1.5
1.3
46.71
9.96
u/ml
3.13
78
312
296
1572
3.05
34.18
9.5
3.3
27.57
82.79
e6/l
0.72
268
1206
35
31
12.03
33.90
2.3
1.9
403.78
514.04
e6/l
0.55
27
25
198
843
3.18
33.84
3.5
2.5
11.00
12.79
umol/l
2.95
193
788
286
1497
3.02
33.80
7.0
2.2
134.65
292.62
u/l
1.69
280
1427
167
660
3.25
32.15
8.8
5.6
1.07
1.04
mmol/l
0.75
162
610
149
550
3.40
32.08
2.7
1.7
—
—
—
0
0
176
725
3.16
31.49
3.5
2.5
20.16
22.46
%
1.41
171
682
86
220
4.49
31.36
2.2
2.0
1.86
1.49
g/l
2.00
79
201
229
1096
2.95
31.30
17.5
5.0
—
—
—
0
0
258
1349
2.81
29.38
9.5
3.2
0.24
0.47
e6/l
1.55
230
985
180
780
3.00
29.13
3.5
2.5
2.20
2.30
g/l
1.42
175
722
349
2139
2.92
29.12
7.8
5.0
33.54
35.55
g/l
8.93
334
2016
110
356
3.65
28.82
2.0
2.4
—
—
—
0
0
390
2546
3.13
28.79
10.6
6.8
9.79
11.51
umol/l
4.61
384
2435
105
331
3.72
28.60
6.8
3.6
7.42
7.42
ph
0.07
89
275
266
1454
2.70
27.16
9.5
4.0
0.00
0.00
estimate
0.50
121
510
143
576
3.05
26.00
11.4
8.7
4.93
5.11
kpa
1.30
137
556
332
2083
2.64
24.72
33.9
11.7
0.00
0.00
e9/l
0.44
314
1716
232
1232
2.59
24.48
5.4
2.8
351.40
344.70
umol/l
0.45
220
1083
196
959
2.68
24.46
7.2
2.9
516.56
524.16
mosm/kgh2o
0.23
190
848
140
576
2.96
24.34
11.3
8.7
7.43
7.42
ph
1.78
90
334
137
568
2.92
23.40
11.6
8.8
1.11
1.06
mmol/l
0.04
122
485
120
466
3.05
23.01
2.8
2.2
0.00
0.03
estimate
0.50
29
96
81
250
3.65
22.51
2.7
2.3
0.00
0.01
estimate
0.49
26
80
137
580
2.85
22.41
5.3
2.7
1.95
1.83
%
0.60
127
525
31
41
7.98
22.30
1.5
1.2
—
—
—
0
0
34
20
18.09
22.09
1.2
1.1
—
—
—
0
0
34
20
18.09
22.09
1.2
1.1
—
—
—
0
0
34
20
18.09
22.09
1.2
1.1
—
—
—
0
0
57
141
4.42
21.46
1.9
2.3
10.88
12.60
mg/l
0.60
51
131
27
8
35.49
21.32
1.5
2.1
—
—
—
0
0
44
89
5.31
21.04
1.6
1.5
—
—
—
0
0
31
45
7.26
20.58
1.5
1.2
—
—
—
0
0
93
331
3.20
20.56
1.6
1.2
137.96
274.03
u/ml
0.79
82
301
113
453
2.91
20.28
3.7
2.8
73.01
70.73
e9/l
0.23
82
341
167
824
2.51
19.79
6.2
3.4
0.81
0.82
mmol/l
0.13
160
787
27
11
25.78
19.73
2.2
1.6
34.07
34.09
%
0.00
27
11
294
1872
2.31
19.28
6.2
3.9
64.31
56.00
ng/l
0.14
247
1373
27
36
7.86
19.26
1.6
1.4
36.78
30.64
%
0.32
20
25
220
1261
2.29
18.29
3.3
2.2
3.40
2.97
mg/l
1.47
204
1091
413
3090
2.64
18.17
9.6
4.8
11.57
1219.18
e6/l
—
7
57
32
55
6.13
18.12
1.5
1.5
55.35
65.88
%
0.69
20
41
71
232
3.39
17.94
7.3
3.8
—
—
—
0
0
44
102
4.62
17.92
6.7
3.5
—
—
—
0
0
30
49
6.44
17.85
4.3
3.4
—
—
—
0
0
331
2263
2.27
17.66
19.7
13.5
1.26
1.23
inr
0.35
280
1866
23
8
29.99
17.55
1.2
1.4
—
—
—
0
0
161
819
2.40
17.54
7.4
2.9
0.47
1.00
e6/l
4.32
122
420
36
73
5.22
17.13
1.2
1.2
2.87
3.75
u/ml
0.43
15
32
267
1703
2.17
16.57
3.9
3.5
2.33
2.36
mmol/l
3.33
254
1543
379
2785
2.33
16.37
9.7
5.2
6.58
6.64
mmol/l
0.23
370
2639
57
172
3.60
16.24
3.4
3.9
47.95
80.59
mg/l
0.44
44
146
57
172
3.60
16.24
3.4
4.0
43.70
52.87
mg/l
0.18
44
145
55
169
3.52
15.24
5.4
3.2
363.97
232.30
mg/l
0.57
31
64
35
77
4.80
15.16
4.6
3.5
0.94
1.05
%
0.13
35
71
38
91
4.43
14.85
8.6
3.8
3.44
2.59
mmol/l
0.97
30
57
230
1434
2.08
14.63
16.3
6.5
—
—
—
0
0
94
403
2.63
14.52
14.4
9.2
—
—
—
0
0
108
496
2.49
14.45
4.3
3.6
7.39
7.39
ph
0.09
64
293
42
112
3.99
14.26
1.5
1.6
—
—
—
0
0
37
90
4.35
14.17
1.3
1.2
—
—
—
0
0
103
467
2.50
14.15
4.9
3.5
2.29
1.95
mmol/l
0.48
97
401
25
43
6.06
14.12
1.7
1.3
116119.74
471971.87
e6/l
0.78
19
30
284
1944
2.02
13.65
9.7
3.9
0.00
0.04
estimate
1.87
115
456
26
50
5.42
13.09
1.0
1.2
—
—
—
0
0
21
15
14.53
12.85
2.0
1.1
8.07
8.89
ug/l
0.30
21
15
43
126
3.63
12.77
2.2
1.6
13796.51
14266.31
e6/l
0.02
35
93
49
158
3.32
12.57
3.4
3.7
1.54
2.57
ratio
0.97
25
92
306
2200
1.95
12.22
4.5
3.1
194.98
125.91
ug/l
1.23
292
2054
67
266
2.74
11.95
4.4
3.3
24.34
24.30
mmol/l
0.05
67
266
87
394
2.45
11.87
5.4
3.8
74.10
81.94
ng/l
0.56
81
349
85
381
2.47
11.86
10.8
3.7
—
—
—
0
0
26
56
4.83
11.54
2.3
1.7
87.41
90.26
%
1.02
26
56
20
35
5.90
11.08
2.4
2.9
47.18
43.55
%
0.40
11
20
178
1095
1.95
11.07
2.8
1.7
1.79
1.32
mg/l
0.99
147
876
94
454
2.31
11.06
2.4
1.5
—
—
—
0
0
134
760
2.03
10.43
3.8
1.9
29.11
29.28
s
0.14
134
739
243
1678
1.84
10.41
7.6
3.3
6.98
7.51
mmol/l
1.27
224
1416
234
1605
1.83
10.18
7.7
3.4
62.82
48.76
mg/l
0.70
185
1020
46
163
3.00
10.08
7.3
3.4
1.56
1.33
mmol/l
0.74
46
158
184
1183
1.86
9.77
5.9
4.1
92.32
90.29
%
0.48
178
1164
221
1507
1.81
9.67
4.2
3.1
—
—
—
0
0
224
1534
1.81
9.66
2.7
2.6
55.24
63.85
u/l
1.16
217
1428
236
1642
1.80
9.65
9.0
4.0
10.42
8.42
mg/mmol
0.49
182
1002
47
174
2.87
9.53
1.6
2.2
10.11
10.57
g/l
0.21
42
159
14
9
15.94
9.07
1.2
1.3
—
—
—
0
0
206
1398
1.78
9.00
7.9
3.4
0.00
0.06
estimate
0.55
115
443
36
120
3.15
8.76
2.7
3.3
1.80
1.90
index
0.04
15
72
37
127
3.06
8.57
3.3
2.2
121.60
130.08
g/l
1.10
25
101
88
459
2.10
8.46
2.2
2.4
0.20
0.21
g/l
0.74
79
428
15
14
10.99
8.34
2.1
1.5
—
—
—
0
0
28
82
3.55
8.34
1.6
1.3
104.33
160.99
au/ml
—
6
27
30
92
3.40
8.34
1.6
1.3
—
—
—
0
0
19
30
6.53
7.78
2.5
3.7
14.73
16.60
%
1.16
19
30
16
20
8.22
7.64
1.0
1.2
—
—
—
0
0
125
761
1.85
7.64
8.8
3.2
2.58
2.63
e6/l
0.02
85
364
12
9
13.61
7.41
1.8
1.2
—
—
—
0
0
221
1594
1.67
7.38
5.2
3.3
35.09
32.60
u/l
0.37
215
1514
27
84
3.34
7.35
1.8
1.5
—
—
—
0
0
74
382
2.09
7.28
3.1
2.4
13.83
7.33
ug/l
0.99
63
338
17
38
4.59
7.23
1.4
1.2
0.39
0.31
u/ml
—
9
22
489
4438
2.71
7.18
52.9
16.6
19.71
23.88
mg/l
3.26
481
3683
153
1017
1.71
6.84
1.7
1.8
53030773.55
19601382.62
pmol/l
0.26
132
852
130
826
1.77
6.82
2.1
1.7
1382.74
1164.90
nmol/l
1.12
105
610
20
55
3.74
6.53
1.2
1.3
—
—
—
0
0
21
60
3.61
6.50
1.2
1.1
—
—
—
0
0
31
114
2.83
6.39
1.2
1.2
—
—
—
0
0
27
92
3.04
6.36
2.9
3.1
0.78
0.84
nmol/l
0.23
22
71
26
87
3.09
6.32
1.2
1.3
267.89
259.12
u/ml
0.05
18
49
12
13
9.42
6.31
2.3
1.2
—
—
—
0
0
10
8
12.71
6.10
1.0
1.1
—
—
—
0
0
17
44
3.96
6.03
1.2
1.1
—
—
—
0
0
17
44
3.96
6.03
1.4
1.2
—
—
—
0
0
11
12
9.34
5.81
3.4
4.3
55.50
48.08
%
0.33
11
12
78
446
1.88
5.72
8.0
4.3
7.36
7.36
ph
0.08
68
321
243
1883
1.55
5.55
2.6
2.2
—
—
—
0
0
17
47
3.71
5.52
2.1
1.2
—
—
—
0
0
18
52
3.55
5.50
2.2
2.2
—
—
—
0
0
75
430
1.87
5.45
1.3
1.5
—
—
—
0
0
18
54
3.42
5.21
1.8
1.8
—
—
—
0
0
33
141
2.43
5.10
1.3
1.3
—
—
—
0
0
275
2218
1.51
5.04
3.9
2.8
—
—
estimate
—
0
0
9
9
10.15
5.04
1.0
1.0
—
—
—
0
0
9
9
10.15
5.04
1.2
1.1
—
—
—
0
0
44
216
2.13
4.94
1.1
1.3
—
—
—
0
0
15
42
3.65
4.80
1.3
1.3
—
—
—
0
0
19
63
3.09
4.72
4.8
2.3
0.83
1.14
g/24h
0.52
14
41
12
22
5.56
4.62
3.3
1.8
73.46
56.94
ug/l
0.50
12
22
33
148
2.31
4.60
1.4
1.2
—
—
—
0
0
153
1110
1.54
4.53
1.3
1.3
0.65
1.18
u/ml
1.41
39
297
8
8
10.13
4.53
8.8
2.8
—
—
—
0
0
17
54
3.22
4.52
1.0
1.1
—
—
—
0
0
9
12
7.61
4.37
1.0
1.3
30.00
27.67
s
—
9
12
140
1012
1.52
4.18
2.5
2.9
2.47
2.46
mmol/l
0.55
122
907
11
21
5.33
4.16
4.2
3.7
1926.45
793.29
u/ml
0.71
11
21
154
1148
1.49
3.94
3.4
2.4
—
—
—
0
0
487
4571
2.03
3.90
30.9
14.9
—
—
—
0
0
102
697
1.58
3.89
1.3
1.2
—
—
—
0
0
198
1553
1.44
3.88
3.5
2.4
—
—
—
0
0
8
11
7.37
3.87
1.6
2.1
—
—
—
0
0
29
134
2.23
3.81
1.3
1.4
188.34
240.14
miu/ml
—
5
60
24
102
2.42
3.80
3.6
2.8
6.46
8.24
pmol/l
0.85
24
102
153
1149
1.47
3.74
11.0
4.1
1.02
1.02
kg/l
0.14
119
784
14
39
3.66
3.72
1.5
1.3
—
—
—
0
0
25
111
2.32
3.60
1.3
1.2
15.67
4.21
e6/l
0.74
18
85
17
63
2.76
3.52
1.6
1.6
42.08
31.97
g/l
2.19
17
55
46
264
1.81
3.36
1.4
1.3
—
—
—
0
0
15
363
0.40
3.32
1.2
1.4
—
—
—
0
0
29
143
2.09
3.27
15.6
10.0
—
—
—
0
0
80
543
1.56
3.13
2.9
3.0
6.81
9.05
umol/l
0.85
72
485
32
168
1.96
3.07
2.5
2.9
—
—
—
0
0
46
272
1.76
3.06
4.6
2.4
1.51
1.17
%
1.76
46
272
7
12
5.89
3.03
1.1
1.3
—
—
—
0
0
14
51
2.79
3.01
1.9
1.5
—
—
—
0
0
10
26
3.90
2.99
1.0
1.0
—
—
—
0
0
16
63
2.59
2.98
33.3
5.3
6.66
6.79
mmol/l
0.09
16
54
483
4578
1.77
2.90
43.6
19.7
139.29
139.71
mmol/l
2.90
477
4488
138
1748
0.71
2.90
3.4
3.3
—
—
—
0
0
184
1487
1.37
2.85
2.0
1.7
17.75
20.57
nmol/l
2.00
166
1268
15
59
2.59
2.81
1.2
1.2
—
—
—
0
0
483
4585
1.75
2.79
43.8
19.9
3.95
3.98
mmol/l
1.75
477
4487
12
39
3.13
2.79
1.3
2.9
460.08
893.72
mg
0.95
12
39
5
6
8.40
2.75
1.0
1.0
—
—
—
0
0
13
48
2.75
2.73
1.3
1.3
—
—
—
0
0
21
99
2.17
2.68
1.3
1.3
—
—
—
0
0
9
24
3.80
2.68
1.0
1.2
—
—
—
0
0
16
67
2.43
2.65
1.7
2.0
29.19
32.63
pg
1.44
16
67
125
958
1.40
2.65
6.3
4.2
310.50
338.55
ng/l
0.07
113
767
7
15
4.71
2.60
1.3
2.8
0.65
0.61
mmol/l
—
7
15
9
25
3.64
2.58
1.6
1.4
—
—
—
0
0
492
4712
1.82
2.51
54.8
21.8
82.07
77.47
umol/l
2.07
487
4654
6
12
5.04
2.41
1.7
3.1
—
—
—
0
0
7
17
4.16
2.36
1.0
1.0
1491.29
1412.41
miu/ml
—
7
17
13
53
2.49
2.29
3.2
2.5
—
—
—
0
0
10
35
2.89
2.22
1.1
1.1
313.50
234.66
mg/l
—
10
29
82
602
1.43
2.21
2.2
2.4
275.11
126.30
ug/g
1.47
68
472
245
2123
1.29
2.20
2.3
2.2
97.23
96.44
pmol/l
0.11
155
1088
9
30
3.03
2.15
1.3
1.7
—
—
—
0
0
10
36
2.81
2.15
1.4
1.1
53.74
36.87
mg/l
—
10
28
12
49
2.48
2.12
1.9
1.3
—
—
—
0
0
11
43
2.59
2.09
1.2
1.1
114.36
105.65
pmol/l
0.19
11
43
7
20
3.53
2.06
1.7
2.1
34.19
41.89
g/l
—
7
20
6
15
4.03
2.04
1.3
1.2
—
—
—
0
0
12
51
2.38
1.96
1.0
1.2
—
—
—
0
0
8
27
2.99
1.94
1.6
1.3
7.37
7.39
ph
—
8
19
385
3567
1.31
1.92
5.0
4.4
15.37
14.83
pmol/l
3.84
367
3262
8
28
2.89
1.87
4.6
3.1
0.75
0.86
index
—
8
28
18
317
0.55
1.72
1.7
1.8
3.57
3.45
mmol/l
—
9
237
8
31
2.60
1.66
1.4
1.3
—
—
—
0
0
6
21
2.88
1.51
3.2
2.3
—
—
—
0
0
16
87
1.87
1.47
1.3
1.9
4.42
4.75
mmol/24h
0.16
16
75
16
87
1.87
1.47
1.1
1.1
—
—
—
0
0
11
53
2.10
1.39
1.2
1.1
—
—
—
0
0
48
352
1.40
1.35
1.4
1.7
—
—
—
0
0
33
225
1.50
1.35
3.6
1.9
—
—
—
0
0
6
131
0.45
1.30
5.2
4.3
—
—
—
0
0
51
382
1.37
1.28
1.2
1.2
—
—
—
0
0
6
25
2.42
1.24
4.3
1.8
—
—
—
0
0
329
3065
1.20
1.21
4.7
3.4
77.72
48.85
u/l
1.53
307
2889
23
149
1.57
1.19
1.7
1.3
253.97
299.66
ug/g
0.52
14
84
7
34
2.07
1.03
2.3
3.5
8.00
7.77
mmol/l
—
7
34
148
1303
1.19
1.00
1.6
1.4
—
—
—
0
0
0
30
0.00
0.97
0.0
17.7
—
938.00
—
0
30
15
93
1.63
0.94
1.3
1.7
—
—
—
0
0
12
195
0.61
0.92
1.2
1.8
—
—
—
0
0
13
78
1.68
0.92
1.2
1.1
—
—
—
0
0
51
404
1.29
0.92
3.2
2.4
6.04
6.11
ph
0.22
34
271
70
580
1.24
0.88
1.4
1.3
—
—
—
0
0
6
30
2.01
0.87
2.5
1.4
74.00
75.03
umol/l
—
6
30
12
74
1.64
0.78
1.3
1.1
—
—
—
0
0
12
74
1.64
0.78
1.3
1.1
—
—
—
0
0
0
26
0.00
0.78
0.0
1.2
—
168.49
—
0
26
409
4224
0.85
0.77
4.7
4.4
1.43
1.27
mmol/l
3.96
388
3892
0
28
0.00
0.76
0.0
1.1
—
—
—
0
0
8
135
0.59
0.74
1.4
1.3
—
—
—
0
0
8
49
1.64
0.62
3.3
2.5
—
—
—
0
0
7
116
0.60
0.58
1.0
1.3
—
—
—
0
0
5
87
0.57
0.56
1.8
1.6
—
—
—
0
0
15
206
0.72
0.56
1.3
1.4
0.32
0.35
mg/l
—
8
86
5
90
0.55
0.56
1.2
1.6
—
—
—
0
0
432
4416
0.87
0.53
5.5
5.2
1.49
1.48
mmol/l
0.06
410
4099
436
4258
1.15
0.53
7.4
6.6
40.10
39.33
mmol/mol
0.49
419
4009
430
4196
1.14
0.53
6.1
5.5
1.97
1.93
mu/l
0.25
402
3873
30
242
1.25
0.52
2.2
2.3
—
—
—
0
0
6
40
1.51
0.51
1.2
1.1
—
3.31
—
0
6
61
531
1.17
0.50
2.3
4.4
3.49
28.93
ug/l
1.06
48
445
15
196
0.76
0.43
1.4
1.3
41.42
25.69
iu/l
1.03
15
166
6
93
0.64
0.42
1.3
1.6
—
—
—
0
0
8
57
1.41
0.42
1.3
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
2.5
—
5.33
—
0
15
443
4503
0.89
0.39
6.1
6.1
2.58
2.69
mmol/l
1.83
420
4185
10
135
0.74
0.36
1.1
1.6
328.60
322.19
mu/l
—
10
126
18
221
0.81
0.34
1.1
1.1
—
—
—
0
0
6
47
1.28
0.32
1.2
1.0
—
—
—
0
0
7
52
1.35
0.31
3.0
2.6
6.84
6.31
umol/l
—
7
35
7
54
1.30
0.30
1.1
1.3
30.17
27.07
ng/l
—
7
54
8
63
1.27
0.28
2.4
1.9
—
—
—
0
0
8
64
1.25
0.27
1.4
1.2
—
—
—
0
0
11
139
0.79
0.27
1.1
1.3
—
—
—
0
0
9
72
1.25
0.25
1.1
1.2
—
—
—
0
0
47
426
1.11
0.25
1.5
1.5
—
—
—
0
0
28
318
0.87
0.25
1.5
1.2
104.66
147.33
u/ml
0.35
13
130
12
147
0.81
0.23
1.1
1.3
—
—
—
0
0
431
4363
0.93
0.23
5.9
5.3
5.72
5.96
mmol/l
4.00
395
4025
12
145
0.82
0.21
1.1
1.3
—
—
—
0
0
12
145
0.82
0.21
1.1
1.3
—
—
—
0
0
46
500
0.91
0.21
1.7
1.6
—
—
—
0
0
439
4437
0.93
0.20
5.5
5.3
4.57
4.62
mmol/l
0.57
414
4138
0
14
0.00
0.20
0.0
1.1
—
0.65
—
0
8
12
143
0.84
0.19
1.1
1.3
—
—
—
0
0
11
132
0.83
0.18
1.2
1.1
—
—
—
0
0
204
1985
1.05
0.17
2.3
2.0
1.53
1.33
mmol/l
2.78
181
1665
78
820
0.94
0.16
3.2
3.3
0.66
0.78
ug/l
1.04
52
542
16
179
0.89
0.12
1.1
1.1
—
—
—
0
0
139
1357
1.03
0.10
4.5
5.8
2.01
2.50
ug/l
0.83
117
1225
5
48
1.04
0.09
3.6
2.6
—
—
—
0
0
5
62
0.80
0.08
5.4
2.7
1.22
1.19
mmol/l
—
5
62
5
62
0.80
0.08
5.4
2.7
4.06
4.00
mmol/l
—
5
62
5
62
0.80
0.08
5.4
2.7
107.80
105.50
mmol/l
—
5
62
31
327
0.94
0.07
1.1
1.2
—
—
—
0
0
6
71
0.84
0.07
1.0
1.1
—
—
—
0
0
60
620
0.96
0.07
1.6
1.3
—
—
—
0
0
8
94
0.85
0.06
1.1
1.2
—
—
—
0
0
20
213
0.94
0.06
1.9
3.2
11.26
1267.02
u/ml
1.17
14
182
13
134
0.97
0.00
1.0
1.1
1.46
1.56
g/l
0.73
13
134
13
127
1.02
0.00
1.0
1.1
—
0.70
—
0
19
14
138
1.01
0.00
1.1
1.1
0.88
0.89
g/l
0.11
14
138
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
42.71
—
0
7
0
8
0.00
-0.00
0.0
4.3
—
6.51
—
0
8
0
9
0.00
-0.00
0.0
1.1
—
68.33
—
0
9
0
9
0.00
-0.00
0.0
1.3
—
1.60
—
0
9
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint RESP_ILL_DIS_CLASS_ELSEWHERE and mortality.

Females

Parameter HR [95% CI] p-value
RESP_ILL_DIS_CLASS_ELSEWHERE 3.745 [3.08, 4.55] < 0.001
Birth year 0.994 [0.99, 1.0] 0.194

During the follow-up period (1.1.1998 — 31.12.2019), 396 out of 1005 females with RESP_ILL_DIS_CLASS_ELSEWHERE died.

Males

Parameter HR [95% CI] p-value
RESP_ILL_DIS_CLASS_ELSEWHERE 3.158 [2.5, 3.98] < 0.001
Birth year 0.988 [0.98, 1.0] 0.009

During the follow-up period (1.1.1998 — 31.12.2019), 342 out of 764 males with RESP_ILL_DIS_CLASS_ELSEWHERE died.

Mortality risk

Mortality risk for people of age

years, who have RESP_ILL_DIS_CLASS_ELSEWHERE.

N-year risk Females Males
1 0.345% 0.573%
5 2.154% 3.715%
10 5.214% 8.745%
15 9.821% 16.302%
20 17.124% 26.876%

Relationships between endpoints

Index endpoint: RESP_ILL_DIS_CLASS_ELSEWHERE – Respiratory disorders in diseases classified elsewhere

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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