≡ Risteys
R14

Documentation Changelog GitHub Contact & Feedback
info icon

ILD related to systemic autoimmune disease

DOID EFO Endpoint Browser

ILD_SYST_AUTO

interstitial lung disease: A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of pulmonary alveoli that extends to the interstitium and beyond leading to diffuse pulmonary fibrosis. Interstitial lung diseases are classified by their etiology (known or unknown causes), and radiological-pathological features.

Suggest a new description

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

  • ILD_ELSEWHERE
209

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

192

6. Filter based on genotype QC (FinnGen only)

177

Control definitions (FinnGen only)

Control exclude
ILD_ENDPOINTS
Control conditions
not ILD_ELSEWHERE

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 177 103 74
Unadjusted period prevalence (%) 0.04 0.04 0.03
Median age at first event (years) 62.08 60.11 64.81

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
180
Matched controls
1800
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
65.8
175.6
113
45
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
51.3
161.6
140
115
L04AX01
ATC
azathioprine; systemic
56.6
137.4
85
28
P01BA02
ATC
hydroxychloroquine; oral
32.0
128.7
112
88
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
+∞
114.0
97
*
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
1927.2
108.0
94
*
L04AA06
ATC
mycophenolic acid; systemic
83.0
104.6
57
10
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
24.7
96.1
82
59
TGC00
NOMESCO Finland
Bronchial lavation
34.1
86.7
60
26
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
23.8
85.1
71
48
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
+∞
75.4
67
*
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
32.8
75.3
52
22
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
42.1
74.4
47
15
UGC12
NOMESCO Finland
Flexible bronchoscopy
16.2
72.8
78
81
J99.0*M05.1
ICD-10 Finland
Rheumatoid lung disease
+∞
64.5
58
*
L04AX03
ATC
methotrexate; systemic
12.7
59.8
75
96
L01BA01
ATC
methotrexate; systemic
24.2
56.2
43
23
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
13.1
55.0
64
73
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
10.6
54.9
83
134
H02AB06
ATC
prednisolone; systemic
30.7
53.9
171
687
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
13.6
52.5
58
61
A07EC01
ATC
sulfasalazine; oral, rectal
12.3
50.9
61
72
GD1AD
NOMESCO Finland
Thorax CT examination
13.2
49.5
55
58
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
10.7
44.7
146
516
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
17.7
42.0
37
26
J18.9
ICD-10 Finland
Pneumonia, unspecified
7.6
41.2
115
341
J99.1*M35.0
ICD-10 Finland
Respiratory disorders in sicca syndrome [Sjögren]
+∞
40.1
37
*
XG410
NOMESCO Finland
Flow-volume spirometry
14.8
39.9
39
33
J99.0
ICD-10 Finland
Rheumatoid lung disease
+∞
34.5
32
*
L88
ICPC
Rheumatoid/seropositive arthritis
13.7
33.7
34
30
J99.1
ICD-10 Finland
Respiratory disorders in other diffuse connective tissue disorders
+∞
32.3
30
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
8.5
30.7
152
702
M05BA04
ATC
alendronic acid; oral
7.1
29.7
55
105
J99.1*M31.3
ICD-10 Finland
Respiratory disorders in Wegener's granulomatosis
+∞
26.7
25
*
M05.1
ICD-10 Finland
Rheumatoid lung disease
+∞
26.7
25
*
J01MA14
ATC
moxifloxacin; systemic
6.7
26.1
50
98
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
48.9
24.5
29
7
L04AA13
ATC
[U] leflunomide
25.6
23.1
32
15
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
6.5
22.6
43
83
ZX120
NOMESCO Finland
Intravenous
5.7
22.5
51
116
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
19.9
22.0
33
20
J99.1*M33.2
ICD-10 Finland
Respiratory disorders in polymyositis
+∞
21.3
20
*
R06.0
ICD-10 Finland
Dyspnoea
4.3
20.9
96
380
R50.9
ICD-10 Finland
Fever, unspecified
4.9
20.5
59
164
M33.2
ICD-10 Finland
Polymyositis
118.2
20.0
21
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
6.8
19.3
34
60
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
4.1
19.3
87
336
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
7.3
18.7
30
48
M31.3
ICD-10 Finland
Wegener granulomatosis
74.5
18.1
20
*
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
5.0
17.0
43
106
R03AK08
ATC
formoterol and beclometasone; inhalant
7.7
16.6
25
37
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
5.4
16.5
37
82
J01MA12
ATC
levofloxacin; systemic
3.8
15.5
64
227
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
4.2
15.2
51
156
M33.9
ICD-10 Finland
Dermatopolymyositis, unspecified
+∞
14.8
14
*
J96.1
ICD-10 Finland
Chronic respiratory failure
19.1
14.7
22
13
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
15.2
14.7
24
18
TPH04
NOMESCO Finland
Cathetrisation of vein
3.5
14.5
70
274
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
6.6
14.4
25
43
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
15.3
14.2
23
17
M33.1
ICD-10 Finland
Other dermatomyositis
150.9
13.6
14
*
R81
ICPC
Pneumonia
6.8
13.3
22
36
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
31.0
13.2
17
6
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
3.5
13.2
62
237
NH3EA
NOMESCO Finland
Feet X-ray examination with load
17.1
13.0
20
13
J99.1*M32.1
ICD-10 Finland
Respiratory disorders in systemic: lupus erythematosus
+∞
12.6
12
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.2
12.4
38
108
L04AD01
ATC
ciclosporin; systemic
19.8
12.3
18
10
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
29.0
12.3
16
6
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
9.7
12.0
24
28
H04.10
ICD-10 Finland
Dry eye syndrome
3.8
11.8
43
138
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.7
11.8
45
149
C03CA01
ATC
furosemide; systemic
3.0
11.8
86
421
H02AB07
ATC
prednisone; oral
3.7
11.5
43
140
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.3
11.3
56
219
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
4.1
11.1
35
101
M05BX04
ATC
denosumab; parenteral
4.5
11.1
30
77
WZC30
NOMESCO Finland
Teaching
3.2
11.0
56
222
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.7
11.0
40
128
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.3
10.9
53
204
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
30.1
10.9
14
5
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
11.1
10.8
20
20
GX1K5
NOMESCO Finland
Diffusion capacity
63.9
10.8
12
*
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
25.1
10.4
14
6
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
13.3
10.1
17
14
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.8
9.9
109
644
M13.9
ICD-10 Finland
Arthritis, unspecified
4.2
9.9
29
79
SPAT1255
SPAT
Intravenous administration of medicine
4.6
9.8
25
61
SPAT1229
SPAT
Assessment of need for aid
4.2
9.6
28
76
R03BA08
ATC
ciclesonide; inhalant
3.8
9.6
33
101
M01CB01
ATC
sodium aurothiomalate; parenteral
31.9
9.5
12
*
L04AA01
ATC
[U] ciclosporin
23.2
9.5
13
6
TNB11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in shoulder joint
+∞
9.5
9
*
356
Kela drug reimbursment
Nintedanib and pirfenidone
+∞
9.5
9
*
J99.1*M33.9
ICD-10 Finland
Respiratory disorders in dermatopolymyositis
+∞
9.5
9
*
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.9
9.1
29
84
A02BC02
ATC
pantoprazole; systemic
3.2
8.9
147
1047
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.9
8.8
54
235
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
17.4
8.7
13
8
M81.4
ICD-10 Finland
Drug-induced osteoporosis
29.1
8.6
11
*
L01EX09
ATC
nintedanib; oral
+∞
8.4
8
*
N08.5*M31.3
ICD-10 Finland
Glomerular disorders in Wegener's granulomatosis
+∞
8.4
8
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.2
8.4
38
139
ZX108
NOMESCO Finland
Inhalation
35.1
8.2
10
*
Z01.8
ICD-10 Finland
Other specified special examinations
2.7
8.0
55
253
R03AC02
ATC
salbutamol; inhalant
2.5
7.8
120
797
L04AB01
ATC
etanercept; parenteral
16.0
7.8
12
8
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
47.1
7.8
9
*
J01AA02
ATC
doxycycline; systemic
3.6
7.7
159
1221
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
26.3
7.7
10
*
J01FA06
ATC
roxithromycin; oral
2.4
7.6
91
539
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
83.4
7.5
8
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.4
7.4
74
403
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
11.6
7.4
13
12
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
11.6
7.4
13
12
M31.1
ICD-10 Finland
Thrombotic microangiopathy
+∞
7.3
7
*
M31.8
ICD-10 Finland
Other specified necrotizing vasculopathies
+∞
7.3
7
*
WX726
NOMESCO Finland
High-flow oxygen therapy
+∞
7.3
7
*
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
+∞
7.3
7
*
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
6.5
7.3
18
30
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.1
7.3
33
120
L01AA01
ATC
cyclophosphamide; systemic
31.4
7.2
9
*
GDA11
NOMESCO Finland
Thoracoscopic biopsy of lung
31.4
7.2
9
*
1XC02, ,
NOMESCO Finland
31.4
7.2
9
*
M05BA07
ATC
risedronic acid; oral
6.9
6.8
16
25
M34.9
ICD-10 Finland
Systemic sclerosis, unspecified
41.7
6.8
8
*
R05
ICD-10 Finland
Cough
2.5
6.7
54
265
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
12.9
6.7
11
9
R28
ICPC
Limited function/disability (R)
12.9
6.7
11
9
M10.9
ICD-10 Finland
Gout, unspecified
3.7
6.7
22
65
A02BC01
ATC
omeprazole; systemic
2.4
6.6
64
342
J05AB11
ATC
valaciclovir; oral
2.7
6.5
42
185
L04AK01
ATC
leflunomide; oral
72.3
6.5
7
*
WW200
NOMESCO Finland
Immunization
8.7
6.5
13
16
B01AA03
ATC
warfarin; systemic
2.5
6.4
47
220
H02AB04
ATC
methylprednisolone; systemic
2.7
6.4
38
160
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
18.8
6.3
9
5
M34.0
ICD-10 Finland
Progressive systemic sclerosis
+∞
6.3
6
*
XF614
NOMESCO Finland
Measurement of pulmonary artery pressure
+∞
6.3
6
*
GD1BT
NOMESCO Finland
Biopsy of lung with X-ray guidance
+∞
6.3
6
*
GX1D5
NOMESCO Finland
Flow volume spirometry
27.7
6.3
8
*
GX2C5
NOMESCO Finland
Short-lasting oximetry
27.7
6.3
8
*
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
27.7
6.3
8
*
SPAT1249
SPAT
Treatment-related counselling outside office
2.2
6.3
81
486
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
3.6
6.2
21
63
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
13.1
6.2
10
8
J01FF01
ATC
clindamycin; systemic
2.3
6.0
61
330

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
79
75
17.99
78.34
4.0
1.4
8.44
6.49
iu/ml
0.30
40
20
71
57
19.92
77.41
3.0
1.3
1.24
1.20
g/l
0.36
71
57
56
49
16.14
57.11
1.8
1.2
3.84
1.90
u/ml
—
14
6
56
49
16.14
57.11
1.8
1.2
2.15
1.93
u/ml
—
25
7
105
215
10.32
57.00
1.9
1.3
664.00
600.75
titre
0.12
45
53
55
59
12.98
48.91
2.1
1.4
—
—
—
0
0
63
99
9.25
41.55
4.6
3.9
—
—
—
0
0
38
6
79.57
34.59
1.3
1.2
—
—
—
0
0
31
25
14.77
32.35
3.5
4.0
—
—
—
0
0
97
295
5.96
32.14
1.6
1.3
127.30
34.90
iu/ml
1.71
57
92
120
469
5.68
28.78
9.1
4.3
—
—
—
0
0
88
269
5.44
28.36
1.6
1.3
61.33
8.15
u/ml
2.52
37
103
64
152
5.98
27.41
9.9
4.7
0.03
0.16
%
1.21
37
43
65
157
5.91
27.32
9.2
4.4
0.36
0.62
%
1.17
39
49
66
162
5.85
27.25
10.0
4.6
0.64
0.94
%
0.71
39
54
125
527
5.49
26.70
22.8
5.9
—
—
—
0
0
170
939
15.59
26.54
28.8
10.1
5.37
4.12
e9/l
8.09
170
814
151
755
7.21
25.95
27.3
6.0
2.42
2.74
%
1.10
151
704
151
758
7.16
25.74
27.6
6.1
8.98
8.84
%
0.21
151
710
151
762
7.09
25.46
26.2
6.0
64.88
57.71
%
9.99
151
723
63
160
5.52
24.80
1.2
1.6
—
—
—
0
0
151
774
6.90
24.63
27.2
6.2
21.27
27.26
%
10.69
151
728
29
33
10.28
23.98
4.3
2.3
—
—
—
0
0
54
125
5.74
23.47
1.5
2.5
—
—
—
0
0
71
209
4.96
23.28
13.6
8.4
7.43
7.41
ph
1.68
50
112
147
757
6.14
23.23
28.2
6.0
0.69
0.68
%
0.12
147
703
67
193
4.94
22.47
2.7
1.4
—
—
—
0
0
69
207
4.78
21.94
13.9
8.4
1.16
0.94
mmol/l
0.16
59
182
60
161
5.09
21.88
10.8
5.0
0.00
0.30
%
0.82
33
44
26
30
9.96
21.20
5.0
3.6
4.43
5.11
e9/l
0.48
26
30
66
196
4.74
21.17
1.2
1.5
—
—
—
0
0
31
18
20.52
20.91
1.5
1.6
—
—
—
0
0
48
111
5.53
20.70
1.1
1.4
—
—
—
0
0
73
238
4.48
20.69
3.6
1.8
—
—
—
0
0
94
372
4.20
20.36
18.4
5.8
—
—
—
0
0
31
22
16.75
19.45
1.6
1.2
53.87
—
u/ml
—
9
0
149
859
5.27
18.22
13.2
7.4
1.21
1.21
mmol/l
0.66
133
739
85
335
3.91
18.09
2.5
1.4
2.40
2.51
g/l
0.17
72
190
28
43
7.53
18.05
5.1
3.3
62.07
60.63
%
0.19
28
43
150
874
5.30
17.96
9.7
4.0
0.00
0.00
estimate
-0.00
50
203
152
896
5.48
17.89
9.6
4.1
0.00
0.00
estimate
-0.00
51
190
130
690
4.18
17.56
7.4
3.7
6.39
6.19
ph
1.16
66
386
150
883
5.19
17.48
9.7
4.1
0.00
7.88
estimate
0.50
52
206
64
218
4.00
16.61
1.4
1.7
—
—
—
0
0
166
1092
7.69
16.00
12.7
4.7
—
2.43
—
0
6
105
512
3.52
15.51
10.2
4.0
0.00
0.00
estimate
-0.00
50
185
47
138
4.26
14.81
11.4
6.6
9.46
9.81
mmol/l
0.13
47
129
13
0
+∞
13.71
1.5
0.0
—
—
—
0
0
33
80
4.83
13.16
2.4
2.2
0.00
0.00
estimate
—
10
28
106
558
3.19
13.11
6.0
4.4
7.39
7.40
ph
0.27
82
390
38
104
4.36
13.03
1.6
1.2
250.24
379.51
u/ml
0.30
30
99
22
37
6.63
12.93
8.5
2.5
—
—
—
0
0
22
21
11.76
12.15
1.7
1.0
—
—
—
0
0
46
152
3.72
12.11
2.1
2.4
0.20
0.21
g/l
0.42
40
141
119
695
3.10
11.81
6.9
4.0
50.82
34.13
ng/l
0.54
108
511
23
28
9.25
11.22
1.4
1.4
—
—
—
0
0
109
624
2.89
10.91
10.2
4.2
30.40
93.20
e6/l
1.15
94
441
44
157
3.39
10.18
2.8
2.1
0.00
0.00
estimate
-0.00
12
34
169
1278
6.28
10.13
26.6
8.3
71.12
79.77
u/l
3.18
169
1198
42
146
3.45
10.12
3.3
1.5
—
—
—
0
0
128
818
2.96
10.08
24.0
12.6
1.31
1.22
inr
1.01
111
669
22
47
5.19
10.07
4.0
1.9
121.80
128.42
g/l
0.47
15
38
82
422
2.73
9.82
3.5
2.1
4.08
2.89
mg/l
2.08
77
362
26
66
4.44
9.71
1.2
4.4
61.86
28.75
mg/l
0.55
19
54
26
66
4.44
9.71
1.2
4.4
48.41
45.22
mg/l
0.12
19
54
48
186
3.16
9.67
3.2
1.6
—
—
—
0
0
99
565
2.67
9.57
8.8
3.4
18.63
152.15
e6/l
0.60
93
424
20
42
5.23
9.31
1.3
1.4
—
—
—
0
0
14
10
15.05
8.85
2.4
8.3
14.44
16.56
%
—
14
10
88
488
2.57
8.83
8.4
3.3
0.42
0.44
e6/l
0.04
80
350
118
754
2.64
8.76
36.8
12.6
0.00
0.00
e9/l
0.45
113
612
22
53
4.59
8.74
12.7
3.2
7.42
7.41
ph
0.22
22
53
36
128
3.27
8.28
9.7
3.1
—
—
—
0
0
56
259
2.69
8.03
18.2
7.5
104.13
104.20
mmol/l
0.04
56
259
111
708
2.48
7.98
3.8
3.0
173.30
129.04
ug/l
1.57
106
656
44
183
2.86
7.69
2.7
3.6
7.40
7.39
ph
0.30
22
98
18
28
7.02
7.64
2.8
1.6
—
—
—
0
0
18
28
7.02
7.64
2.8
1.6
—
—
—
0
0
18
28
7.02
7.64
2.8
1.6
—
—
—
0
0
18
28
7.02
7.64
2.8
1.6
—
—
—
0
0
42
171
2.90
7.63
3.8
3.6
2.56
1.91
mmol/l
0.54
37
147
19
33
6.31
7.46
1.2
6.5
—
—
—
0
0
25
75
3.71
7.42
9.8
3.0
—
—
—
0
0
105
668
2.37
7.38
10.9
3.9
0.00
0.00
estimate
-0.00
49
167
22
61
3.97
7.28
1.2
4.2
1.31
2.68
ratio
—
9
32
70
377
2.40
7.17
2.9
1.7
1.59
1.59
mg/l
0.01
59
312
14
18
8.33
6.75
1.2
1.2
—
—
—
0
0
11
9
12.92
6.67
1.0
1.1
—
—
—
0
0
31
117
2.99
6.39
28.7
8.9
26.34
25.09
mmol/l
0.94
31
117
14
20
7.49
6.35
1.2
1.2
—
—
—
0
0
16
28
6.16
6.31
1.1
1.2
2.83
5.23
u/ml
—
6
13
13
17
8.15
6.24
2.5
2.2
87.12
89.14
%
0.57
13
17
17
35
5.25
5.92
12.5
3.1
5.14
4.97
kpa
0.34
17
35
17
35
5.25
5.92
12.5
3.1
7.89
8.50
kpa
0.68
17
35
68
388
2.21
5.88
9.5
4.0
—
0.00
—
0
5
11
12
9.67
5.87
1.0
1.1
—
—
—
0
0
66
373
2.21
5.83
1.3
1.2
0.65
1.86
u/ml
1.10
26
99
33
138
2.70
5.62
11.1
4.1
—
—
—
0
0
34
146
2.64
5.50
3.0
2.3
9.91
7.97
ug/l
0.23
29
135
17
48
3.81
5.47
1.4
1.1
—
—
—
0
0
9
8
11.76
5.35
1.0
1.3
—
—
—
0
0
26
99
2.90
5.26
1.4
1.2
—
—
—
0
0
11
15
7.73
5.22
1.2
1.1
—
—
—
0
0
35
158
2.51
5.10
22.9
9.7
—
—
—
0
0
13
24
5.75
5.02
1.5
1.4
—
—
—
0
0
10
15
6.99
4.53
4.5
3.9
—
—
—
0
0
16
50
3.41
4.45
3.9
3.2
533.38
282.76
mg/l
—
8
17
9
12
7.83
4.41
1.7
1.1
—
—
—
0
0
34
165
2.31
4.21
3.1
3.4
82.88
73.51
e9/l
0.41
26
112
77
517
1.86
3.91
4.9
3.2
—
—
—
0
0
13
35
3.92
3.68
1.1
1.1
—
—
—
0
0
14
46
3.22
3.61
1.6
1.4
308.13
237.88
ug/g
—
8
25
24
107
2.43
3.57
2.8
3.5
23.88
24.49
mmol/l
0.54
24
107
13
37
3.70
3.48
1.5
1.3
—
—
—
0
0
9
18
5.20
3.41
1.1
1.3
—
—
—
0
0
23
103
2.41
3.39
3.9
2.6
1.61
1.24
%
0.82
23
103
7
10
7.23
3.39
1.3
1.5
—
—
—
0
0
6
7
8.81
3.28
1.3
1.1
—
—
—
0
0
101
764
1.73
3.24
4.0
2.8
—
—
estimate
—
0
0
75
522
1.75
3.24
16.6
6.2
—
—
—
0
0
19
80
2.54
3.18
1.1
1.3
—
—
—
0
0
22
100
2.37
3.15
3.5
2.6
0.68
0.60
%
0.55
22
100
41
240
1.92
3.09
1.3
1.3
—
—
—
0
0
5
5
10.23
2.99
4.2
1.8
—
—
—
0
0
71
496
1.71
2.98
9.9
3.5
0.00
0.01
estimate
0.50
49
161
34
189
1.98
2.97
2.8
2.2
301.96
128.44
ug/g
1.05
28
154
27
139
2.11
2.89
5.1
4.0
7.39
7.36
ph
0.60
22
93
11
33
3.48
2.86
1.6
1.3
112.60
145.93
au/ml
—
5
9
55
362
1.75
2.83
2.6
2.7
2.47
2.46
mmol/l
0.12
50
323
8
18
4.60
2.83
1.1
1.2
—
—
—
0
0
7
14
5.15
2.75
2.3
6.3
8.00
8.02
mmol/l
—
7
14
10
30
3.47
2.65
4.2
2.2
8.58
10.76
mmol/l
—
10
30
5
7
7.30
2.56
4.0
6.1
52.10
41.57
%
—
5
7
5
7
7.30
2.56
1.0
1.1
—
—
—
0
0
7
16
4.51
2.50
3.6
1.1
—
—
—
0
0
8
21
3.94
2.49
2.1
2.0
—
—
—
0
0
55
375
1.67
2.46
12.5
4.1
1.02
1.02
kg/l
0.32
40
253
19
91
2.22
2.43
2.2
2.5
—
—
—
0
0
5
8
6.39
2.38
1.2
1.0
—
—
—
0
0
11
40
2.86
2.32
1.1
1.2
—
—
—
0
0
6
13
4.73
2.29
1.0
1.1
—
—
—
0
0
11
42
2.72
2.18
1.2
1.2
—
—
—
0
0
13
55
2.47
2.17
7.6
13.7
—
—
—
0
0
146
1292
1.69
2.02
56.6
22.0
14.72
13.75
%
10.27
146
1285
8
27
3.05
1.96
1.0
1.1
—
—
—
0
0
5
11
4.64
1.95
1.0
1.2
—
—
—
0
0
5
11
4.64
1.95
1.0
1.4
0.60
1.00
u/field
—
5
6
170
1587
2.28
1.81
35.2
14.9
—
—
—
0
0
69
532
1.48
1.73
3.5
2.4
—
—
—
0
0
10
41
2.52
1.67
2.8
3.4
5.49
11.09
pmol/l
—
10
41
21
121
1.83
1.67
1.2
1.2
—
—
—
0
0
15
77
2.03
1.64
1.1
1.6
—
—
—
0
0
5
14
3.64
1.62
1.6
1.6
—
—
—
0
0
8
32
2.57
1.61
1.0
1.1
—
—
—
0
0
31
203
1.64
1.59
1.4
1.3
—
—
—
0
0
38
263
1.56
1.56
6.2
2.0
31.27
29.10
s
1.73
38
254
7
27
2.66
1.53
1.6
2.2
28.71
31.70
pg
—
7
27
170
1603
2.09
1.47
51.0
20.5
139.15
139.75
mmol/l
2.14
170
1573
172
1638
2.13
1.44
39.0
12.7
24.72
24.98
u/l
0.06
172
1584
18
104
1.81
1.43
1.4
1.3
—
32.63
—
0
10
7
29
2.47
1.40
1.0
1.0
—
—
—
0
0
170
1607
2.04
1.39
51.2
20.7
3.99
3.98
mmol/l
0.17
170
1573
5
17
2.99
1.37
1.6
1.0
—
—
—
0
0
5
17
2.99
1.37
1.0
1.1
—
—
—
0
0
5
17
2.99
1.37
1.0
3.5
—
—
—
0
0
5
17
2.99
1.37
1.6
1.0
—
—
—
0
0
5
18
2.83
1.29
1.4
1.8
—
—
—
0
0
25
165
1.60
1.26
1.3
1.4
—
—
—
0
0
45
579
0.70
1.23
3.5
3.6
—
—
—
0
0
172
1645
2.03
1.20
61.3
22.8
81.52
78.24
umol/l
0.81
172
1628
5
20
2.54
1.16
1.0
1.2
—
—
—
0
0
78
653
1.34
1.13
2.7
2.3
—
—
—
0
0
11
59
1.92
1.10
4.5
2.1
1.92
1.52
mg/l
0.65
11
49
12
67
1.85
1.07
1.6
3.0
—
—
—
0
0
10
53
1.94
1.03
2.5
3.7
1.21
1.43
index
—
5
30
0
29
0.00
0.98
0.0
1.3
—
—
—
0
0
6
116
0.50
0.98
1.2
1.5
—
—
—
0
0
0
31
0.00
0.97
0.0
1.4
—
—
—
0
0
0
31
0.00
0.97
0.0
1.4
—
—
—
0
0
0
32
0.00
0.96
0.0
1.3
—
—
—
0
0
0
32
0.00
0.96
0.0
1.3
—
—
—
0
0
71
603
1.29
0.89
5.5
3.3
7.42
7.32
mmol/l
0.07
64
494
87
759
1.28
0.89
2.2
2.1
96.45
97.56
pmol/l
0.09
62
354
172
1663
1.77
0.87
73.9
26.1
8.31
6.72
e9/l
12.33
172
1629
172
1663
1.77
0.87
73.4
26.1
262.37
245.84
e9/l
2.53
172
1637
172
1663
1.77
0.87
73.4
26.0
92.18
91.52
fl
0.90
172
1647
172
1663
1.77
0.87
76.0
26.6
39.45
40.15
%
1.49
172
1647
172
1663
1.77
0.87
73.6
26.0
4.33
4.46
e12/l
2.93
172
1627
172
1663
1.77
0.87
73.2
25.9
29.95
30.41
pg
2.11
172
1647
172
1663
1.77
0.87
74.2
26.2
128.08
134.58
g/l
7.94
172
1646
53
437
1.30
0.83
8.8
4.0
89.00
89.33
%
0.03
53
432
6
34
1.79
0.77
1.0
1.4
—
206.34
—
0
11
12
77
1.60
0.70
2.8
1.9
—
—
—
0
0
68
590
1.25
0.69
5.8
3.4
65.34
45.86
mg/l
0.46
53
372
35
280
1.31
0.68
7.4
3.0
2.66
2.66
e6/l
0.00
25
133
69
608
1.22
0.60
7.2
4.2
9.19
8.07
mg/mmol
0.14
52
359
0
23
0.00
0.58
0.0
1.3
—
—
—
0
0
17
218
0.76
0.46
1.2
1.3
—
—
—
0
0
7
50
1.42
0.45
1.1
1.1
—
—
—
0
0
26
311
0.81
0.41
3.1
3.5
0.64
0.80
ug/l
0.80
18
209
0
17
0.00
0.41
0.0
1.4
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
288.62
—
0
13
148
1528
0.82
0.40
5.4
5.4
5.74
6.02
mmol/l
3.06
139
1400
75
703
1.11
0.26
2.1
2.1
1.42
1.31
mmol/l
0.79
66
578
48
441
1.12
0.24
1.5
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
2.3
—
—
—
0
0
0
10
0.00
0.21
0.0
12.6
—
0.68
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
0.06
—
0
5
0
10
0.00
0.21
0.0
1.2
—
177.35
—
0
10
0
13
0.00
0.21
0.0
2.1
—
—
—
0
0
0
14
0.00
0.20
0.0
2.4
—
—
—
0
0
13
152
0.84
0.17
1.8
1.6
—
—
—
0
0
15
167
0.89
0.11
1.8
2.7
36.60
34.01
u/l
0.20
15
134
5
48
1.04
0.09
1.0
2.3
52.24
59.27
%
—
5
48
11
97
1.14
0.09
1.2
1.3
—
—
—
0
0
154
1550
0.96
0.03
5.7
5.5
4.45
4.63
mmol/l
1.37
149
1425
50
508
0.98
0.01
4.2
5.9
1.74
2.78
ug/l
0.89
44
454
12
114
1.06
0.01
1.5
1.4
—
—
—
0
0
158
1578
1.01
0.00
6.2
6.4
2.51
2.69
mmol/l
1.75
153
1451
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
2.8
—
1.11
—
0
5
0
5
0.00
0.00
0.0
1.0
—
57.60
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
5.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
5.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
1.35
—
0
6
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
14.3
—
926.22
—
0
9
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
12152.67
—
0
6
9
93
0.97
-0.00
4.4
4.1
1.02
1.02
ratio
—
9
87
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
57.33
—
0
6

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: ILD_SYST_AUTO – ILD related to systemic autoimmune disease

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).