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Primary angle-closure glaucoma

DOID EFO Endpoint Browser PheWeb

H7_GLAUCCLOSEPRIM

primary angle closure glaucoma: The sudden increase of intraocular pressure, resulting in pain and an abrupt decrease in visual acuity.

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Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H40.2
  • Hospital discharge: ICD-9 — 3652
  • Hospital discharge: ICD-8 — 37500|37511
  • Cause of death: ICD-10 — H40.2
  • Cause of death: ICD-9 — 3652
  • Cause of death: ICD-8 — 37500|37511

2 out of 7 registries used, show all original rules.

1927

4. Check minimum number of events

None

1927

5. Include endpoints

None

1927

6. Filter based on genotype QC (FinnGen only)

1702

Control definitions (FinnGen only)

Control exclude
H7_GLAUCOMA

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H40
Name in latin
Glaucoma congestivum primarium

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 17902 11851 5834
Only index persons 13200 8791 4409
Unadjusted period prevalence (%)
Whole population 0.28 0.34 0.16
Only index persons 0.27 0.32 0.17
Median age at first event (years)
Whole population 68.78 69.73 66.90
Only index persons 67.76 68.71 65.87

-FinnGen-

Key figures

All Female Male
Number of individuals 1702 1000 702
Unadjusted period prevalence (%) 0.34 0.36 0.32
Median age at first event (years) 66.83 66.57 67.19

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1766
Matched controls
17660
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
S01EC03
ATC
dorzolamide; ophthalmic
63.3
318.8
177
31
H40.22
ICD-10 Finland
Chronic glaucoma with closed ventricular angle
16384.0
307.7
1017
*
S01EB01
ATC
pilocarpine; ophthalmic
150.3
307.7
246
19
S01ED01
ATC
timolol; ophthalmic
45.9
307.7
441
127
S01EE01
ATC
latanoprost; ophthalmic
50.9
307.7
706
228
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
307.4
307.7
385
16
S01EA05
ATC
brimonidine; ophthalmic
195.9
307.7
321
20
S01EC04
ATC
brinzolamide; ophthalmic
77.2
307.7
433
74
H40.9
ICD-10 Finland
Glaucoma, unspecified
225.7
307.7
235
12
H40.20
ICD-10 Finland
Acute glaucoma with closed ventricular angle
+∞
307.7
644
*
S01EE03
ATC
bimatoprost; ophthalmic
49.5
307.7
210
48
S01EE05
ATC
tafluprost; ophthalmic
42.2
307.7
308
88
S01EX03, ,
ATC
64.2
307.7
244
44
H40.0
ICD-10 Finland
Glaucoma suspect
156.2
307.7
572
54
S01EC01
ATC
acetazolamide; systemic
49.9
307.7
296
71
114
Kela drug reimbursment
Glaucoma
94.4
307.7
1067
281
CHC05
NOMESCO Finland
Iridotomy
743.9
307.7
808
20
XCK00
NOMESCO Finland
Perimetry
22.1
307.7
473
288
S01ED51
ATC
timolol, combinations; ophthalmic
84.9
307.7
1014
276
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
27.3
292.8
204
84
S01EE04
ATC
travoprost; ophthalmic
37.0
267.5
168
50
Z96.1
ICD-10 Finland
Presence of intraocular lens
5.5
259.1
727
1996
S01EC54
ATC
brinzolamide, combinations; ophthalmic
114.9
250.6
128
12
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
569.9
208.5
203
*
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
28.6
206.1
140
53
S01EA03
ATC
apraclonidine; ophthalmic
33.8
196.2
126
40
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
364.3
194.6
193
6
XCW99
NOMESCO Finland
Other investigative procedure of eye
5.4
186.1
449
1053
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
4.3
182.0
1209
5955
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.5
179.5
588
1761
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
5.6
178.6
396
860
S01ED02
ATC
betaxolol; ophthalmic
59.7
171.4
96
17
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
268.5
168.6
170
7
H40
ICD-10 Finland
Glaucoma
51.3
168.1
97
20
XCH00
NOMESCO Finland
Eye pressure measurement
8.0
165.8
242
343
CS494
NOMESCO Finland
Other visual field testing
17.3
161.7
136
85
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
21.5
154.8
117
58
H40.21
ICD-10 Finland
Intermittent glaucoma with closed ventricular angle
+∞
147.0
139
*
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
+∞
126.6
120
*
H40.11
ICD-10 Finland
Low pressure glaucoma
59.8
123.2
69
12
H40.29
ICD-10 Finland
Other [primary] glaucoma with closed ventricular angle
+∞
111.7
106
*
H25.1
ICD-10 Finland
Senile nuclear cataract
3.0
111.1
958
5006
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
6.8
104.8
172
274
XCK10
NOMESCO Finland
Photography of fundus of eye
4.0
100.5
328
945
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.8
96.9
946
5163
CHD15
NOMESCO Finland
Trabeculectomy and iridectomy
957.5
93.8
91
*
WX140
NOMESCO Finland
Parabulbar anesthesy
5.2
87.2
191
400
3652B
ICD-9 Finland
Glaucoma, Primary angle-closure glaucoma[KROONINEN AHDASKULMAGLAUKOOMA]
+∞
83.0
79
*
CJB10
NOMESCO Finland
Laser discission of secondary cataract
3.3
77.8
350
1233
S01BA07
ATC
fluorometholone; ophthalmic
10.2
77.1
88
90
CHD00
NOMESCO Finland
Laser trabeculoplasty
206.6
76.9
79
*
H20.1
ICD-10 Finland
Chronic iridocyclitis
15.2
71.0
63
43
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.4
70.9
1014
6311
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.8
69.7
431
1808
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
+∞
65.0
62
*
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
4.0
64.3
195
526
F93
ICPC
Glaucoma
30.7
63.7
42
14
H26.4
ICD-10 Finland
After-cataract
2.8
62.2
379
1568
CHD65
NOMESCO Finland
Nonpenetrating glaucoma surgery
+∞
58.7
56
*
3652A
ICD-9 Finland
Glaucoma, Primary angle-closure glaucoma[AKUUTTI AHDASKULMAGLAUKOOMA]
+∞
57.6
55
*
XCH05
NOMESCO Finland
Eye pressure longterm registration
71.2
54.5
62
9
H40.8
ICD-10 Finland
Other glaucoma
533.4
52.8
52
*
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
64.2
48.5
56
9
37511
ICD-8 Finland
Glaucoma, Chronicum irritativum sive congestivum
+∞
43.9
42
*
ZXA10
NOMESCO Finland
Bilateral
2.2
42.6
440
2282
37500
ICD-8 Finland
Glaucoma, Primary, acute
+∞
41.8
40
*
CHD99
NOMESCO Finland
Other filtering operation
+∞
41.8
40
*
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
+∞
39.7
38
*
3651A
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA SIMPLEX (AVOKULMA)]
+∞
38.7
37
*
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
5.9
37.1
68
120
SPAT1009
SPAT
Measurement of intraocular pressure
6.9
36.2
56
83
S01EA02
ATC
dipivefrine; ophthalmic
364.5
36.1
36
*
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
4.6
36.0
87
196
H40.2
ICD-10 Finland
Primary angle-closure glaucoma
+∞
35.5
34
*
CS2P4
NOMESCO Finland
Optic nerve head imaging
42.9
34.1
42
10
XCW10
NOMESCO Finland
Assessment of vision
7.0
34.0
52
76
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
6.5
32.2
53
84
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
5.9
32.0
58
101
H40.12
ICD-10 Finland
Pigmentary glaucoma
307.5
29.9
30
*
37510
ICD-8 Finland
Glaucoma, Chronicum simplex
+∞
29.2
28
*
S01BA01
ATC
dexamethasone; ophthalmic
3.6
29.2
101
296
H26.2
ICD-10 Finland
Complicated cataract
6.5
28.7
47
74
Z3229
NOMESCO Finland
Other healthcare associate professional
2.4
27.8
203
896
CHD35
NOMESCO Finland
Laser goniopuncture
+∞
27.1
26
*
S01FA01
ATC
atropine; ophthalmic
10.9
26.9
29
27
H57.1
ICD-10 Finland
Ocular pain
3.7
26.8
85
235
A10AA01, ,
ATC
4.7
26.5
62
136
CHC03
NOMESCO Finland
Laser iridoplasty
+∞
26.1
25
*
H3603, E103,
ICD-10 Finland
24.5
25.7
36
15
S01EE51
ATC
latanoprost and netarsudil; ophthalmic
94.8
25.7
28
*
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
9.3
25.7
31
34
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.8
25.3
79
216
S01BC03
ATC
diclofenac; ophthalmic
4.1
25.2
71
180
3708
FHL
Trabeculectomy or equivalent
+∞
25.1
24
*
ZXA05
NOMESCO Finland
Left side
1.8
24.8
526
3405
CK2P4
NOMESCO Finland
Optic nerve head light layer imaging (OCT)
56.8
24.1
28
5
CFW99
NOMESCO Finland
Other operation on conjunctiva
243.2
23.7
24
*
S01BA04
ATC
prednisolone; ophthalmic
4.0
23.2
66
169
H43.1
ICD-10 Finland
Vitreous haemorrhage
3.9
22.9
67
175
CHC00
NOMESCO Finland
Iridotomy
+∞
21.9
21
*
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
+∞
21.9
21
*
CKC15
NOMESCO Finland
Panretinal photocoagulation
6.4
21.9
36
57
H16.0
ICD-10 Finland
Corneal ulcer
2.9
21.2
100
354
F43
ICPC
Eye, Other diagnostic procedure
4.5
21.1
51
115
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
8.1
20.9
28
35
CKC12
NOMESCO Finland
Photocoagulation of retina
3.2
20.5
84
274
H34.8
ICD-10 Finland
Other retinal vascular occlusions
3.6
20.1
66
187
H40.19
ICD-10 Finland
Other primary glaucoma with open ventricular angle
+∞
19.8
19
*
WX142
NOMESCO Finland
Sub-tenon anesthesy
8.2
19.7
26
32
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
7.5
19.5
28
38
A10AB01
ATC
insulin (human); parenteral
3.3
19.1
72
223
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
2.4
18.9
132
569
H40.3
ICD-10 Finland
Glaucoma secondary to eye trauma
192.0
18.6
19
*
H26.02
ICD-10 Finland
Presenil cataract
3.6
18.5
61
173
H25.0
ICD-10 Finland
Senile incipient cataract
2.2
18.2
163
782
CHF15
NOMESCO Finland
Cryotherapy of ciliary body
+∞
17.7
17
*
CKD40
NOMESCO Finland
Endophotocoagulation of retina
4.7
17.6
40
86
CKC10
NOMESCO Finland
Local photocoagulation of retina
3.7
16.9
54
150
3626
FHL
Extracapsular cataract surgery and implantation of an artificial lens
3.6
16.9
56
160
H04.10
ICD-10 Finland
Dry eye syndrome
1.9
16.7
216
1185
3650A
ICD-9 Finland
Glaucoma, Borderline glaucoma [glaucoma suspect][SUSPICIO GLAUCOMATIS (AVOKULMA)]
+∞
16.7
16
*
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
13.5
16.5
28
21
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic
4.6
16.1
38
84
ZXA00
NOMESCO Finland
Right side
1.6
15.9
521
3700
F38
ICPC
Eye, Other laboratory test NEC
3.9
14.8
43
112
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
11.4
14.8
27
24
CHD10
NOMESCO Finland
Trabeculectomy
+∞
14.6
14
*
CHB99
NOMESCO Finland
Other operation on anterior chamber and anterior chamber angle
151.2
14.5
15
*
E10
ICD-10 Finland
Type 1 diabetes mellitus
4.8
14.3
32
68
H40.1
ICD-10 Finland
Primary open-angle glaucoma
53.8
13.8
16
*
H04AA01
ATC
glucagon; nasal, parenteral
4.8
13.8
31
66
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
4.3
13.6
35
83
H25.8
ICD-10 Finland
Other senile cataract
1.7
13.6
286
1811
ZXC20
NOMESCO Finland
Use of chemical agents
3.2
13.6
53
168
37597
ICD-8 Finland
Glaucoma, Suspicio glaucomatis
+∞
13.6
13
*
CKD60
NOMESCO Finland
Anterior vitrectomy
4.8
13.3
30
64
H36.00
ICD-10 Finland
Diabetic background retinopathy
4.3
13.2
34
81
CS444, ,
SPAT
40.4
13.2
16
*
H52.0
ICD-10 Finland
Hypermetropia
3.4
13.1
46
137
A10AB04
ATC
insulin lispro; parenteral
3.1
13.0
54
178
A10AA02, ,
ATC
2.6
13.0
74
290
3661A
ICD-9 Finland
Cataract, Senile cataract
3.4
12.9
45
133
ZYC01
NOMESCO Finland
Remote contact by phone
2.3
12.9
101
459
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
9.7
12.7
25
26
S01EX
ATC
Other antiglaucoma preparations
+∞
12.5
12
*
S01BC05
ATC
ketorolac; ophthalmic
2.2
12.4
105
492
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
11.7
12.3
22
19
H35.36
ICD-10 Finland
Macular cyst
5.4
12.3
24
45
A10AE06
ATC
insulin degludec; parenteral
2.7
12.0
63
237
T89
ICPC
Diabetes insulin dependent
2.7
12.0
64
243
S01FA04
ATC
cyclopentolate; ophthalmic
4.1
11.6
31
76
H3601, E103,
ICD-10 Finland
11.2
11.5
21
19
CA1ME
NOMESCO Finland
Ultrasound oculometry
5.1
11.5
24
48
37520
ICD-8 Finland
Glaucoma, Secondary
+∞
11.5
11
*
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
11.9
11.3
20
17
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
4.6
11.2
26
57
H44.5
ICD-10 Finland
Degenerated conditions of globe
43.6
10.9
13
*
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
2.6
10.5
60
236
3704
FHL
Iridectomy
+∞
10.4
10
*
Q15.0
ICD-10 Finland
Congenital glaucoma
+∞
10.4
10
*
A10AB05
ATC
insulin aspart; parenteral
1.9
10.4
142
792
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
2.4
10.3
71
306
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
23.5
10.2
14
6
H21.0
ICD-10 Finland
Hyphaema
13.2
10.2
17
13
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
3.1
10.1
40
129
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
1.9
10.0
125
678
CFB00
NOMESCO Finland
Suture of conjunctiva
55.3
9.7
11
*
H3603, E113,
ICD-10 Finland
4.5
9.6
23
52
CKD15
NOMESCO Finland
Injection of vitreous substitute
9.1
9.5
19
21
CKD20
NOMESCO Finland
Removal of vitreous body substitute
7.2
9.5
22
31
CJ2M4
NOMESCO Finland
Scans and measurement printouts for intraocular lens power calculation
3.9
9.4
27
70
TCG20
NOMESCO Finland
Laser suture lysis in cornea or sclera
+∞
9.4
9
*
E0000UV, ,
ATC
1.4
9.2
659
5324
A10AC01
ATC
insulin (human); parenteral
1.8
9.1
145
847
Z94.0
ICD-10 Finland
Kidney transplant status
4.6
9.1
21
46
XCD10
NOMESCO Finland
Electrophysiological examination of eye
2.6
8.9
52
207
ZXE00
NOMESCO Finland
One hour or less
1.4
8.7
606
4864
WX002
NOMESCO Finland
Sedation and analgesia
1.5
8.6
335
2428
127
Kela drug reimbursment
Transplant complication
3.8
8.5
25
66
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
3.5
8.5
29
85
CHC10
NOMESCO Finland
Peripheral iridectomy
90.5
8.4
9
*
3711
FHL
Cyclodiateria or cryocoagulation
+∞
8.3
8
*
3651B
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA CAPSULARE (AVOKULMA)]
+∞
8.3
8
*
TCA15
NOMESCO Finland
Retrobulbar therapeutic injection into orbit
+∞
8.3
8
*
A10AE05
ATC
insulin detemir; parenteral
2.0
8.2
91
474
R42
ICD-10 Finland
Dizziness and giddiness
1.4
8.1
433
3320
171
Kela drug reimbursment
Degludekinsuliini
17.2
8.1
12
7
H27.1
ICD-10 Finland
Dislocation of lens
6.8
8.1
19
28
Z3231
NOMESCO Finland
Registered nurse
1.4
7.9
440
3393
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
6.4
7.7
19
30
137
Kela drug reimbursment
Uraemia requiring dialysis
4.4
7.7
19
44
H33.0
ICD-10 Finland
Retinal detachment with retinal break
2.3
7.6
54
236
S01FA02
ATC
scopolamine; ophthalmic
4.1
7.5
20
49
S18
ICPC
Laceration/cut
1.3
7.3
782
6644
3650B
ICD-9 Finland
Glaucoma, Borderline glaucoma [glaucoma suspect][SUSPICIO GLAUCOMATIS (AHDASKULMA)]
+∞
7.3
7
*
H21.1
ICD-10 Finland
Other vascular disorders of iris and ciliary body
+∞
7.3
7
*
3656X
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA SECUNDARIA ALIA SEU NUD]
+∞
7.3
7
*
3705
FHL
Iridectomy or iridotomy using a laser under general anesthesia
+∞
7.3
7
*
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
6.9
7.3
17
25
CKC20
NOMESCO Finland
Cryopexy of undetached retina
9.4
7.3
14
15
H54.0
ICD-10 Finland
Blindness, binocular
15.8
7.2
11
7
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
7.2
540
4359
H27.0
ICD-10 Finland
Aphakia
7.3
7.2
16
22
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.7
7.2
123
736
H31.4
ICD-10 Finland
Choroidal detachment
20.1
7.1
10
5
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
3.6
7.0
22
61
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
6.3
6.9
17
27
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
6.9
658
5489
H3600, E103,
ICD-10 Finland
5.9
6.9
18
31
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
6.9
1041
9242
F99
ICPC
Eye/adnexa disease other
4.0
6.9
19
48
H36.01
ICD-10 Finland
Diabetic maculopathy
3.2
6.9
26
82
XCD20
NOMESCO Finland
Photoangiography of eye
2.7
6.8
36
137
H54.4
ICD-10 Finland
Blindness, monocular
9.3
6.8
13
14
CWD00
NOMESCO Finland
Reoperation for superficial heamorrhage in eye and adjacent structures
40.2
6.8
8
*
F01
ICPC
Eye pain
2.4
6.7
44
186
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
2.6
6.7
38
150
CH2X4
NOMESCO Finland
Optical coherence tomography (OCT) of iris and iridocorneal angle
22.6
6.7
9
*
S01AD03
ATC
aciclovir; ophthalmic
2.1
6.7
61
297
Z94.7
ICD-10 Finland
Corneal transplant status
6.9
6.5
15
22
WZC30
NOMESCO Finland
Teaching
1.4
6.5
258
1873
WZC00, ,
SPAT
1.5
6.3
212
1490
3719
FHL
Other measure in this category
+∞
6.3
6
*
S01EB02
ATC
carbachol; ophthalmic
+∞
6.3
6
*
H21.5
ICD-10 Finland
Other adhesions and disruptions of iris and ciliary body
+∞
6.3
6
*
XCH05, ,
SPAT
26.8
6.2
8
*
L04AA06
ATC
mycophenolic acid; systemic
2.9
6.2
28
98
CK2M4
NOMESCO Finland
Macular light layer imaging (OCT)
3.7
6.2
19
52
H25.2
ICD-10 Finland
Senile cataract, morgagnian type
5.0
6.2
18
36
B05DA
ATC
Isotonic solutions
5.0
6.2
18
36
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
6.3
6.2
15
24

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
564
4540
1.36
7.78
5.5
4.6
0.00
0.00
estimate
0.96
220
1552
57
257
2.26
7.50
3.9
2.9
4.46
4.32
e9/l
0.17
57
257
641
5293
1.33
7.36
2.3
2.2
146.71
212.25
u/l
2.95
588
4990
1403
12967
1.40
7.34
6.2
5.7
1.96
2.04
mu/l
1.07
1267
11744
265
1894
1.47
7.22
2.1
1.8
—
—
—
0
0
204
1389
1.53
7.03
4.6
4.0
1.23
1.23
mmol/l
0.00
177
1187
693
5859
1.30
6.50
5.5
4.6
0.62
0.49
estimate
0.08
207
1400
1278
11715
1.33
6.49
8.8
8.5
81.62
81.68
u/l
0.02
1203
11036
761
6519
1.29
6.44
5.0
4.4
59.89
84.67
ng/l
0.61
623
5106
831
7203
1.29
6.41
2.7
2.5
81.03
79.99
nmol/l
0.43
727
6321
983
8719
1.29
6.28
8.1
7.4
1.22
1.21
mmol/l
0.39
822
7513
633
5306
1.30
6.28
5.2
4.2
7.40
7.40
ph
0.48
473
3849
920
8098
1.28
6.22
18.9
18.6
1.30
1.34
inr
1.37
791
6791
1531
14476
1.43
6.10
26.7
24.2
4.01
4.00
mmol/l
0.91
1505
14162
62
315
2.00
6.08
4.3
2.8
61.05
58.97
%
0.71
62
315
1529
14456
1.43
6.07
26.4
24.0
139.52
139.57
mmol/l
0.27
1503
14162
904
7965
1.28
5.96
5.3
4.5
0.00
0.00
estimate
-0.00
238
1701
380
2987
1.35
5.89
1.3
1.3
1.77
1.43
u/ml
0.19
111
739
1144
10394
1.29
5.81
6.3
5.6
4933.23
2018.57
e6/l
0.26
13
169
911
8064
1.27
5.66
5.2
4.5
0.03
0.93
estimate
0.49
238
1772
891
7871
1.27
5.61
7.4
6.6
1.21
1.21
mmol/l
0.29
809
7217
917
8130
1.27
5.60
5.3
4.5
0.24
0.19
estimate
0.06
222
1661
1544
14667
1.42
5.55
29.0
26.3
82.77
81.31
umol/l
0.72
1522
14444
1472
13876
1.37
5.52
21.6
19.6
25.24
26.95
mg/l
1.11
1276
11762
654
5582
1.27
5.43
3.8
3.4
6.71
6.87
mmol/l
0.49
547
4607
16
33
4.88
5.43
1.7
1.5
—
—
—
0
0
168
1161
1.49
5.41
6.1
4.7
—
—
—
0
0
600
5070
1.28
5.40
3.5
2.6
72.63
77.09
u/l
0.08
553
4664
1191
10921
1.28
5.39
4.9
4.6
15.21
15.13
pmol/l
0.49
1072
9822
369
2923
1.33
5.39
5.1
4.9
—
—
—
0
0
864
7631
1.26
5.35
5.2
5.1
34.75
34.78
g/l
0.06
786
7106
419
3385
1.31
5.31
3.8
3.1
514.97
522.50
mosm/kgh2o
0.30
373
2948
740
6425
1.26
5.29
4.5
4.0
6.32
6.29
ph
0.27
399
3459
741
6438
1.26
5.26
13.7
12.5
0.00
0.00
e9/l
0.31
623
5174
657
5632
1.27
5.21
4.6
4.1
8.88
8.81
mg/mmol
0.02
399
3428
1549
14760
1.40
5.12
32.6
29.7
246.36
245.44
e9/l
0.21
1514
14382
1549
14761
1.40
5.11
32.5
29.6
91.69
91.72
fl
0.12
1527
14539
1549
14762
1.40
5.10
32.4
29.5
30.34
30.37
pg
0.37
1528
14539
1549
14762
1.40
5.10
32.5
29.6
4.35
4.37
e12/l
0.62
1506
14333
1549
14762
1.40
5.10
33.0
30.2
39.47
39.29
%
0.72
1526
14531
1518
14419
1.38
5.10
13.9
13.3
22.98
24.49
u/l
4.43
1465
13913
1549
14765
1.40
5.07
32.5
29.7
6.94
6.89
e9/l
0.38
1507
14331
1549
14766
1.40
5.06
32.8
29.9
131.01
131.54
g/l
0.70
1526
14552
1408
13235
1.31
5.01
8.0
7.3
41.44
40.26
mmol/mol
4.36
1283
12146
1040
9449
1.24
4.78
5.7
5.2
7.02
6.82
mmol/l
2.09
991
9035
639
5508
1.25
4.72
3.9
3.4
53.49
46.90
mg/l
0.30
391
3456
466
3875
1.28
4.66
3.7
2.8
4.32
5.52
e6/l
2.17
429
3529
1141
10489
1.25
4.65
6.1
5.2
—
2.21
—
0
17
670
5826
1.24
4.53
3.9
3.8
—
—
—
0
0
935
8455
1.22
4.27
6.1
6.6
11.11
12.16
umol/l
2.37
872
8056
64
374
1.74
4.16
1.7
1.9
10.33
12.87
mg/l
1.32
56
345
681
5976
1.23
4.13
3.1
3.3
1480.14
1678.63
ng/l
0.79
594
5209
873
7862
1.22
4.08
6.1
6.3
0.19
0.19
e9/l
0.07
749
6719
324
2619
1.29
4.01
1.9
2.0
30.03
29.72
s
0.22
314
2536
1186
11031
1.23
3.96
4.9
4.5
14.54
14.64
mm/h
0.07
1103
10204
428
3585
1.26
3.95
1.9
1.8
18731587.11
20365079.48
pmol/l
0.03
331
2907
79
496
1.62
3.95
1.4
1.5
—
—
—
0
0
1424
13533
1.27
3.81
6.0
5.7
6.21
6.06
mmol/l
2.75
1280
12127
551
4762
1.23
3.80
4.2
3.5
0.41
0.51
e6/l
0.56
438
3565
845
7630
1.21
3.71
6.1
6.1
0.04
0.04
e9/l
0.01
720
6418
403
3376
1.25
3.70
1.9
1.8
1332.42
1163.96
nmol/l
2.07
297
2526
195
1487
1.35
3.65
4.8
3.6
91.38
94.44
ng/l
0.20
162
1243
62
377
1.67
3.54
2.8
2.3
225.32
71.84
ug/min
0.65
38
220
11
26
4.25
3.50
6.2
4.2
—
—
—
0
0
622
5478
1.21
3.50
4.5
3.7
53.87
83.41
e6/l
0.69
500
4235
518
4481
1.22
3.50
4.1
3.5
2134.97
0.00
estimate
—
6
21
1434
13680
1.26
3.45
6.6
6.3
2.51
2.57
mmol/l
1.77
1301
12405
840
7614
1.20
3.45
6.1
6.1
0.62
0.61
e9/l
0.43
712
6396
339
2806
1.26
3.44
2.9
2.6
2.26
2.28
g/l
0.24
297
2569
70
447
1.59
3.31
3.3
2.7
1.77
1.73
mg/l
0.12
65
392
675
6015
1.20
3.31
3.5
3.6
2.35
2.36
mmol/l
0.56
608
5385
852
7757
1.19
3.27
6.1
6.1
1.81
1.87
e9/l
0.38
739
6682
180
1387
1.33
3.16
1.7
1.5
—
—
—
0
0
59
366
1.63
3.15
3.9
4.5
—
—
—
0
0
1339
12718
1.22
3.14
4.6
4.5
1.25
1.28
mmol/l
0.71
1194
11346
160
1216
1.35
3.09
1.8
1.5
—
—
—
0
0
41
232
1.79
3.05
1.8
1.3
—
—
—
0
0
55
339
1.64
3.03
4.9
5.3
8.49
8.39
kpa
0.18
55
333
55
339
1.64
3.03
4.9
5.3
2.20
2.84
mmol/l
0.99
41
239
55
339
1.64
3.03
4.9
5.3
5.10
5.09
kpa
0.04
55
333
466
4041
1.21
3.01
5.0
4.0
0.14
0.26
estimate
0.22
194
1338
203
1604
1.30
2.99
3.0
2.5
5.14
6.99
ug/l
1.54
168
1383
14
51
2.76
2.98
2.3
2.2
0.62
0.61
mmol/l
0.37
14
51
1387
13241
1.22
2.98
5.5
5.4
1.50
1.47
mmol/l
1.19
1255
11965
936
8643
1.18
2.91
8.6
9.6
4.47
4.24
e9/l
1.30
799
7426
22
102
2.17
2.87
1.1
1.2
—
—
—
0
0
1396
13355
1.22
2.83
5.7
5.4
4.47
4.50
mmol/l
0.57
1265
12157
22
103
2.15
2.81
2.3
2.4
51.06
54.29
iu/ml
—
7
19
310
2603
1.23
2.75
3.0
2.7
20.55
21.48
%
0.69
278
2402
48
294
1.65
2.73
7.1
1.4
0.97
0.85
nmol/l
0.49
37
239
351
2987
1.22
2.73
3.0
2.7
11.49
12.00
umol/l
0.75
313
2771
172
1348
1.31
2.71
4.2
4.6
1.88
0.11
%
0.57
34
362
80
553
1.47
2.69
4.4
4.3
7.40
7.41
ph
0.91
80
547
727
6608
1.17
2.67
3.4
3.1
141.83
138.40
ug/l
0.14
653
6045
36
205
1.77
2.66
1.8
1.3
197.00
167.61
au/ml
—
10
63
148
1140
1.33
2.64
4.5
6.8
24.31
24.53
mmol/l
0.27
138
1082
173
1362
1.30
2.64
3.9
4.3
0.10
0.10
%
0.03
40
396
214
1736
1.26
2.58
1.3
1.3
—
—
—
0
0
1165
11007
1.17
2.55
26.0
24.5
13.95
13.91
%
0.38
1146
10852
16
69
2.33
2.48
2.2
2.8
1565.00
1861.90
ml
0.71
16
58
670
6080
1.16
2.47
5.1
4.3
122.37
124.05
e6/l
0.01
514
4366
787
7231
1.16
2.46
3.0
2.9
—
—
estimate
—
0
0
523
4656
1.18
2.45
2.4
2.4
3.03
3.00
mg/l
0.11
453
3981
403
3513
1.19
2.42
5.4
4.8
1.02
1.02
kg/l
0.70
264
2364
774
7112
1.16
2.40
6.2
6.3
2.85
2.79
%
0.33
704
6610
221
1818
1.25
2.37
1.6
1.5
—
—
—
0
0
170
1363
1.27
2.28
3.9
4.1
0.86
0.64
%
0.50
43
438
630
5720
1.16
2.26
2.1
2.0
1.30
1.31
mmol/l
0.20
498
4705
22
113
1.96
2.25
1.0
1.1
—
—
—
0
0
773
7129
1.15
2.23
6.3
6.4
9.19
9.10
%
0.36
703
6625
581
5253
1.16
2.20
1.7
1.8
22.00
20.14
nmol/l
1.88
481
4346
590
5342
1.16
2.19
5.7
6.0
—
—
—
0
0
107
813
1.34
2.14
1.4
1.4
—
—
—
0
0
177
1439
1.26
2.13
4.0
4.2
1.52
0.87
%
0.84
44
473
48
315
1.54
2.12
1.4
1.3
20.64
60.75
e6/l
0.67
39
232
329
2849
1.19
2.12
3.0
3.0
0.81
0.81
mmol/l
0.34
301
2639
641
5854
1.15
2.09
2.3
2.3
—
—
—
0
0
48
317
1.53
2.07
1.5
1.3
221.83
627.98
e6/l
0.52
40
247
5
10
5.01
2.07
3.2
4.8
—
—
—
0
0
496
4451
1.16
2.06
6.5
5.9
2.57
4.26
ug/l
1.03
435
3967
186
1531
1.24
2.01
1.8
1.6
—
—
—
0
0
48
320
1.51
1.99
1.1
1.1
—
—
—
0
0
828
7713
1.14
1.99
2.3
2.3
98.29
94.92
pmol/l
1.06
411
3948
767
7112
1.14
1.97
6.4
6.4
0.67
0.66
%
0.21
698
6604
379
3347
1.17
1.93
1.6
1.7
1.34
1.50
mg/l
0.44
302
2637
8
186
0.43
1.93
1.4
1.7
—
—
—
0
0
564
5129
1.15
1.93
4.4
4.5
—
—
—
0
0
282
2431
1.19
1.92
2.4
2.1
—
—
—
0
0
255
2179
1.20
1.91
1.3
1.2
—
—
—
0
0
194
1615
1.23
1.90
2.2
2.8
66.16
66.03
g/l
0.09
173
1463
275
2368
1.19
1.90
7.9
5.4
1.06
1.03
mmol/l
0.79
252
2164
304
2641
1.18
1.89
1.5
1.5
2.41
2.59
g/l
0.97
184
1519
36
553
0.64
1.88
1.3
1.8
3.37
3.42
mmol/l
0.06
23
395
222
1880
1.21
1.84
1.3
1.3
540.00
543.45
titre
0.01
56
452
20
108
1.86
1.82
2.0
2.2
—
—
—
0
0
924
8713
1.13
1.75
3.3
3.3
54.89
54.96
u/l
0.01
835
7994
7
24
2.92
1.72
1.0
1.2
—
—
—
0
0
220
1875
1.20
1.71
3.6
3.2
4.83
4.75
e9/l
0.05
177
1565
103
1302
0.78
1.71
3.9
3.2
6.01
6.08
ph
0.40
76
937
103
809
1.29
1.68
3.0
3.2
4.36
4.37
pmol/l
0.04
88
708
30
188
1.61
1.66
1.2
1.5
72.64
62.10
%
0.70
14
127
71
530
1.35
1.65
1.8
1.9
20.70
21.07
s
0.31
66
487
225
1929
1.19
1.65
5.7
7.6
94.83
95.18
%
0.30
214
1859
209
1782
1.20
1.63
6.2
8.0
120.02
118.92
g/l
0.32
202
1732
70
525
1.35
1.59
1.5
1.4
256.32
278.37
ug/g
0.42
44
306
10
44
2.28
1.55
1.2
1.2
—
—
—
0
0
19
322
0.59
1.54
3.9
4.0
25.58
38.89
u/ml
0.68
19
315
0
44
0.00
1.51
0.0
1.2
—
63.25
—
0
34
104
833
1.26
1.48
3.2
4.0
41.31
101.38
u/ml
2.53
97
805
171
1445
1.20
1.48
2.2
2.1
382.70
384.58
nmol/l
0.04
155
1326
123
1006
1.24
1.47
3.3
2.4
0.66
0.61
%
0.84
123
1001
87
683
1.29
1.46
2.8
3.6
35.12
65.62
mg/l
1.06
68
600
135
1118
1.22
1.44
5.6
7.4
25.20
24.96
mmol/l
0.26
135
1111
87
685
1.28
1.43
2.8
3.6
45.63
135.66
mg/l
0.61
68
599
448
4086
1.13
1.43
2.8
2.9
344.90
352.98
umol/l
0.77
375
3512
23
141
1.64
1.42
1.3
1.4
16.51
28.86
%
—
10
95
48
654
0.73
1.39
1.5
1.3
—
—
—
0
0
27
174
1.56
1.37
1.6
2.3
—
—
—
0
0
141
1180
1.21
1.37
3.1
3.9
5.20
5.18
kpa
0.12
133
1126
101
1240
0.80
1.35
1.7
1.6
—
—
—
0
0
411
3743
1.13
1.34
3.1
3.1
2.47
2.47
mmol/l
0.04
370
3346
138
1155
1.21
1.34
3.1
3.9
7.41
7.42
ph
0.64
118
973
61
464
1.33
1.31
12.9
12.2
—
—
—
0
0
283
2521
1.15
1.30
1.3
1.3
31.35
38.69
iu/ml
0.66
85
797
765
7221
1.10
1.29
6.4
6.4
25.81
26.15
%
0.36
704
6800
10
48
2.09
1.27
1.2
1.3
—
—
—
0
0
87
699
1.26
1.25
1.4
1.3
—
—
—
0
0
41
295
1.40
1.25
1.7
1.8
3.85
4.73
mmol/24h
1.45
34
249
6
25
2.40
1.24
1.0
1.0
—
—
—
0
0
42
304
1.39
1.24
1.2
1.1
21.16
8.02
eliau/ml
—
5
24
5
20
2.50
1.15
1.0
1.0
—
—
—
0
0
166
1436
1.17
1.15
1.4
1.4
—
—
—
0
0
121
1018
1.20
1.14
3.3
2.4
1.25
1.13
%
0.78
121
1010
8
40
2.00
1.12
3.4
2.0
9.63
10.19
%
—
8
32
78
630
1.25
1.10
3.4
4.1
24.73
25.07
mmol/l
0.43
68
570
14
81
1.73
1.09
8.8
6.4
5.60
35.21
ug/l
—
9
48
514
4796
1.10
1.07
2.9
3.2
30.97
34.57
u/l
1.32
475
4514
241
2156
1.14
1.06
6.0
7.3
0.97
1.01
mmol/l
0.04
194
1782
565
5300
1.10
1.05
2.5
2.6
—
—
—
0
0
38
280
1.36
1.04
1.4
1.2
—
—
—
0
0
38
280
1.36
1.04
1.3
1.2
—
—
—
0
0
127
1085
1.18
1.04
1.3
1.2
—
—
—
0
0
5
22
2.28
1.03
1.2
1.1
18.80
154.76
ng/l
—
5
14
184
1623
1.15
1.01
3.9
2.8
4.47
4.41
kpa
0.16
178
1582
209
1863
1.14
0.99
4.5
3.4
1.73
1.94
mmol/l
0.34
187
1617
242
2179
1.13
0.98
6.1
7.3
5.05
5.11
kpa
0.43
230
2081
0
30
0.00
0.97
0.0
7.3
—
5.25
—
0
30
0
30
0.00
0.97
0.0
2.5
—
39.68
—
0
23
242
2180
1.13
0.97
6.1
7.3
12.03
11.94
kpa
0.09
232
2083
18
116
1.56
0.96
1.3
1.3
—
—
—
0
0
22
149
1.48
0.95
1.1
1.2
2.62
4.74
u/ml
0.82
13
78
19
125
1.53
0.94
1.7
1.4
5.01
7.08
g/l
2.84
13
90
19
125
1.53
0.94
1.7
1.4
0.32
0.46
g/l
1.91
13
91
19
125
1.53
0.94
1.7
1.4
2.61
3.01
g/l
0.77
13
92
103
873
1.19
0.94
5.2
3.2
25.59
25.38
mmol/l
0.27
97
848
240
2168
1.12
0.92
6.1
7.3
7.42
7.42
ph
0.19
136
1186
404
3756
1.10
0.91
1.4
1.3
—
—
—
0
0
437
4079
1.09
0.90
2.4
2.5
—
—
—
0
0
29
210
1.39
0.90
1.4
1.1
373.86
294.99
u/ml
0.52
21
111
37
281
1.32
0.87
1.7
2.0
0.78
0.89
%
0.83
24
201
41
526
0.77
0.87
4.8
3.5
0.75
0.82
nmol/l
0.74
35
432
55
441
1.26
0.86
1.5
2.3
129.67
127.04
g/l
0.31
45
344
13
201
0.64
0.81
1.2
1.2
1.54
1.56
g/l
0.09
13
201
212
1919
1.12
0.81
4.6
3.4
5.86
5.83
kpa
0.16
207
1872
181
1623
1.13
0.81
2.0
2.2
162.78
148.09
ug/g
0.18
144
1278
81
683
1.19
0.81
2.9
2.7
—
—
—
0
0
0
24
0.00
0.79
0.0
1.1
—
—
—
0
0
183
1645
1.13
0.79
9.4
6.4
10.99
10.80
mmol/l
0.14
175
1567
0
25
0.00
0.79
0.0
2.5
—
1.74
—
0
25
738
7074
1.07
0.78
6.2
6.3
58.86
58.48
%
0.40
686
6699
19
131
1.46
0.78
1.3
1.2
—
—
—
0
0
488
4607
1.08
0.78
6.7
6.6
—
—
—
0
0
51
412
1.24
0.77
1.4
1.3
—
—
—
0
0
15
222
0.67
0.77
1.3
1.2
0.73
0.92
g/l
3.34
15
222
71
595
1.20
0.76
2.6
3.0
3601.13
375.04
mg/l
0.51
24
218
74
623
1.20
0.76
2.9
3.3
2.29
4.71
ratio
0.77
43
372
9
54
1.67
0.74
1.1
1.0
1510.22
1557.59
miu/ml
—
9
54
5
25
2.00
0.72
2.0
1.2
19.32
31.99
mg/l
—
5
20
48
389
1.24
0.72
1.2
1.3
55.58
58.95
mmol/l
0.29
38
314
366
3431
1.08
0.70
4.5
4.4
243.45
296.59
ng/l
0.22
314
2933
177
1602
1.12
0.70
8.0
7.8
—
—
—
0
0
18
127
1.42
0.68
1.8
1.4
—
—
—
0
0
7
118
0.59
0.68
1.0
1.3
—
—
—
0
0
44
538
0.81
0.66
1.3
1.4
—
—
—
0
0
5
28
1.79
0.66
1.4
1.5
—
—
—
0
0
83
717
1.17
0.66
1.4
1.3
—
—
—
0
0
26
197
1.32
0.66
2.6
2.4
0.80
1.16
g/24h
0.61
15
107
12
78
1.54
0.65
1.2
1.4
—
—
—
0
0
256
2372
1.09
0.65
1.4
1.3
15.75
13.88
u/ml
0.15
96
810
28
360
0.77
0.64
4.0
4.0
30.54
26.84
mg/l
0.24
19
262
16
112
1.43
0.63
2.2
1.7
101.01
96.21
ng/l
0.07
16
112
211
1942
1.10
0.62
4.7
3.4
7.37
7.38
ph
0.65
116
1138
106
938
1.14
0.62
2.6
2.5
—
—
—
0
0
18
130
1.39
0.61
1.2
1.2
331.08
325.38
nmol/l
—
10
108
8
50
1.60
0.61
1.9
2.3
—
—
—
0
0
27
209
1.30
0.60
1.1
1.1
6.86
121.11
iu/ml
—
7
31
15
105
1.43
0.60
1.4
1.3
1.93
1.37
u/ml
—
8
60
48
400
1.21
0.58
1.1
1.2
—
990.83
—
0
12
7
114
0.61
0.58
1.7
1.8
—
—
—
0
0
8
54
1.48
0.57
1.0
1.4
133.75
166.48
mmol/24h
—
8
54
189
1741
1.10
0.56
4.8
4.6
7.35
7.36
ph
0.33
132
1227
25
194
1.29
0.56
1.6
2.1
—
—
—
0
0
16
116
1.38
0.54
2.4
2.6
—
—
—
0
0
6
39
1.54
0.53
1.2
2.5
—
—
—
0
0
151
1381
1.10
0.53
3.9
2.5
0.46
0.57
e6/l
0.25
141
1328
6
40
1.50
0.51
3.7
2.0
30.50
27.91
%
—
6
34
131
1192
1.11
0.51
4.4
2.9
124.56
126.47
g/l
0.38
124
1160
6
41
1.46
0.50
1.3
1.2
—
—
—
0
0
16
213
0.75
0.50
1.4
1.6
—
—
—
0
0
319
3021
1.07
0.49
3.5
3.2
1.43
1.34
e6/l
0.09
191
1640
10
68
1.47
0.47
1.2
1.2
—
—
—
0
0
7
49
1.43
0.46
1.0
1.9
15.11
15.41
pmol/l
—
7
37
86
770
1.12
0.46
1.2
1.2
120.03
123.29
u/ml
0.03
23
282
30
246
1.22
0.45
1.1
1.2
—
—
—
0
0
8
121
0.66
0.45
1.5
2.2
7.79
8.52
mmol/l
—
8
121
23
183
1.26
0.45
1.4
1.3
—
—
nmol/l
—
0
0
90
810
1.12
0.44
3.3
3.9
—
—
—
0
0
10
69
1.45
0.44
1.0
1.1
—
9.75
—
0
15
293
2781
1.06
0.43
3.6
3.3
1.83
2.64
e6/l
1.51
158
1392
27
221
1.23
0.42
2.9
1.7
0.66
0.87
g/l
0.40
20
175
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
30.23
—
0
17
0
17
0.00
0.40
0.0
1.6
—
—
—
0
0
17
132
1.29
0.40
2.4
3.1
20.43
22.59
mg/l
0.05
12
99
237
2241
1.07
0.40
2.3
2.5
1.80
1.84
%
0.27
206
1975
434
4177
1.05
0.40
3.9
3.6
—
—
—
0
0
7
104
0.67
0.39
1.1
1.1
—
—
—
0
0
5
35
1.43
0.39
1.4
1.5
—
—
—
0
0
9
68
1.33
0.37
1.1
2.6
551.00
1512.46
u/ml
—
9
68
11
147
0.75
0.37
1.2
1.1
0.18
0.99
u/ml
—
6
80
9
69
1.31
0.37
1.3
1.6
262.11
321.88
mu/l
—
9
50
5
37
1.35
0.37
1.4
1.2
—
—
—
0
0
6
42
1.43
0.35
1.2
1.2
—
—
—
0
0
13
99
1.32
0.35
1.2
1.8
—
—
—
0
0
14
108
1.30
0.35
1.4
1.5
1960.00
1822.52
ml
0.34
14
103
18
144
1.25
0.35
1.2
1.2
9.54
10.75
u/l
0.33
13
132
53
471
1.13
0.34
5.6
4.8
—
—
—
0
0
185
1746
1.07
0.34
2.2
2.6
67.31
69.44
e9/l
0.39
141
1291
26
218
1.20
0.34
1.5
1.8
175.96
201.36
pmol/l
0.70
26
203
29
246
1.18
0.34
2.7
2.8
—
—
—
0
0
28
237
1.18
0.33
1.3
1.4
61935.62
52667.71
e6/l
0.12
16
131
16
127
1.26
0.33
1.3
1.1
13.00
2.87
eliau/ml
—
8
38
38
435
0.87
0.33
1.3
1.2
—
—
—
0
0
6
87
0.69
0.33
1.0
1.2
142.67
131.89
nmol/l
—
6
87
171
1614
1.07
0.32
2.2
2.2
0.00
0.01
estimate
0.50
39
292
6
47
1.28
0.32
2.0
1.9
—
—
—
0
0
47
418
1.13
0.31
1.1
1.1
—
—
—
0
0
8
107
0.75
0.29
3.0
1.8
—
—
—
0
0
16
195
0.82
0.29
2.5
3.9
—
—
—
0
0
18
216
0.83
0.28
1.1
1.1
—
—
—
0
0
90
835
1.08
0.28
2.5
2.1
—
—
—
0
0
22
257
0.85
0.26
2.2
2.7
—
—
—
0
0
11
86
1.28
0.26
1.5
1.7
—
—
—
0
0
31
272
1.14
0.26
1.4
1.8
48.00
41.75
nmol/l
0.57
31
257
41
367
1.12
0.26
3.7
8.3
105.57
105.24
mmol/l
0.17
35
325
41
367
1.12
0.26
3.7
8.3
11.71
11.00
mmol/l
0.60
35
325
110
1034
1.07
0.25
8.3
9.9
15.61
15.59
%
0.03
105
990
19
224
0.85
0.25
1.4
1.5
—
—
—
0
0
14
114
1.23
0.25
1.0
1.3
—
—
—
0
0
9
76
1.19
0.24
1.2
2.1
—
46.34
—
0
5
188
1802
1.05
0.23
2.6
2.6
6.86
9.19
umol/l
0.89
156
1601
34
380
0.89
0.23
1.1
2.6
31.89
32.63
umol/l
0.06
28
329
207
1989
1.05
0.23
3.6
4.1
11.78
19.49
ug/l
0.54
168
1641
25
218
1.15
0.23
1.4
1.4
—
—
—
0
0
94
883
1.07
0.23
1.9
2.4
12.10
12.55
nmol/l
0.17
82
781
269
2601
1.04
0.23
3.6
3.5
0.75
0.80
ug/l
0.45
197
1792
14
168
0.83
0.22
1.1
1.2
—
—
—
0
0
85
796
1.07
0.22
2.2
2.2
0.00
1.14
estimate
0.50
27
221
7
95
0.74
0.22
1.1
1.1
—
—
—
0
0
12
146
0.82
0.22
2.0
2.3
0.86
1.70
u/field
—
7
73
63
584
1.08
0.22
1.6
1.7
6.87
7.12
iu/ml
0.02
12
142
57
526
1.09
0.22
3.7
7.1
1.26
1.35
mmol/l
0.49
47
460
0
11
0.00
0.21
0.0
1.5
—
29.60
—
0
5
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
27
239
1.13
0.21
1.3
1.3
42.58
31.03
iu/l
0.71
18
202
20
173
1.16
0.21
1.1
1.5
20.11
31.81
ng/l
0.85
20
173
53
489
1.09
0.20
1.5
1.6
17.52
18.21
u/ml
0.04
12
78
0
14
0.00
0.20
0.0
1.0
—
77.71
—
0
14
84
791
1.07
0.20
1.4
2.0
1.17
2.03
ug/l
0.63
67
685
9
111
0.81
0.20
1.1
1.0
289.67
295.07
mg/l
—
9
97
6
49
1.23
0.20
1.3
1.1
—
—
—
0
0
6
49
1.23
0.20
1.3
1.1
—
—
—
0
0
6
49
1.23
0.20
1.3
1.1
—
—
—
0
0
16
137
1.17
0.18
1.1
1.5
—
—
—
0
0
13
109
1.19
0.18
4.3
3.0
—
—
—
0
0
22
194
1.14
0.18
1.1
1.1
—
—
—
0
0
11
132
0.83
0.18
1.2
1.1
—
—
—
0
0
7
60
1.17
0.17
1.1
1.3
9.71
24.21
%
—
7
55
165
1591
1.04
0.17
3.1
3.1
228.59
235.15
ng/l
0.07
152
1465
16
184
0.87
0.17
2.8
3.1
14.45
11.28
index
0.88
11
97
71
670
1.06
0.17
1.4
1.5
—
22.78
—
0
16
10
120
0.83
0.16
1.2
1.0
3.03
2.53
u/ml
—
5
51
18
204
0.88
0.16
1.3
1.3
—
—
—
0
0
11
130
0.85
0.16
1.5
1.1
107.45
103.16
pmol/l
0.10
11
130
9
82
1.10
0.15
1.3
1.4
—
—
—
0
0
19
212
0.90
0.14
2.5
2.7
—
—
—
0
0
31
286
1.09
0.13
3.1
3.9
1.28
1.49
%
0.14
25
252
13
113
1.15
0.13
2.0
2.6
15.38
16.09
%
0.27
13
113
9
108
0.83
0.13
1.0
1.1
—
11.18
—
0
21
18
161
1.12
0.13
1.2
1.4
—
—
—
0
0
33
306
1.08
0.13
1.2
1.2
—
—
—
0
0
14
123
1.14
0.12
1.1
1.1
—
—
—
0
0
29
313
0.93
0.12
1.4
1.5
—
—
—
0
0
38
356
1.07
0.12
1.6
1.8
3.27
20.11
iu/l
0.51
14
140
16
143
1.12
0.11
1.1
1.5
—
—
—
0
0
175
1707
1.03
0.11
1.8
2.2
0.20
0.20
g/l
0.36
162
1580
14
124
1.13
0.11
1.1
1.1
—
—
—
0
0
153
1571
0.97
0.11
3.6
2.4
44.93
35.59
u/l
0.73
120
1312
43
454
0.95
0.10
1.5
1.6
0.43
0.33
mg/l
0.34
19
198
14
125
1.12
0.10
1.0
1.2
—
—
—
0
0
42
398
1.06
0.10
1.2
1.1
—
—
—
0
0
10
87
1.15
0.09
1.0
1.0
—
—
—
0
0
16
145
1.10
0.09
1.1
1.5
—
—
—
0
0
16
145
1.10
0.09
1.1
1.5
—
—
—
0
0
11
97
1.13
0.09
2.3
3.0
1.00
0.92
index
0.16
11
97
18
165
1.09
0.08
1.0
1.1
—
—
—
0
0
6
58
1.03
0.08
1.0
1.6
—
—
—
0
0
42
440
0.95
0.08
1.0
1.3
—
22.04
—
0
8
18
195
0.92
0.08
2.1
3.5
52.35
57.78
%
0.40
13
167
94
915
1.03
0.07
1.3
1.8
1.50
1.55
g/l
0.23
81
798
6
70
0.86
0.07
2.3
4.3
—
—
—
0
0
69
712
0.97
0.07
2.4
2.6
9.98
10.37
g/l
0.37
62
621
129
1263
1.02
0.07
1.5
1.5
—
—
—
0
0
8
78
1.03
0.07
1.0
1.0
—
—
—
0
0
7
80
0.87
0.07
1.0
1.1
—
—
—
0
0
7
82
0.85
0.07
1.6
1.3
11.19
22.50
umol/l
—
7
75
22
206
1.07
0.07
1.0
1.0
—
—
—
0
0
8
92
0.87
0.06
1.0
1.1
—
—
—
0
0
9
101
0.89
0.06
4.0
1.8
44.24
38.58
%
—
9
101
18
193
0.93
0.06
1.1
1.2
—
—
—
0
0
96
982
0.98
0.06
1.2
1.3
—
—
—
0
0
19
203
0.94
0.06
1.5
1.4
—
—
—
0
0
19
203
0.94
0.06
1.5
1.4
—
—
—
0
0
19
203
0.94
0.06
1.5
1.4
—
—
—
0
0
19
203
0.94
0.06
1.5
1.4
—
—
—
0
0
42
436
0.96
0.06
1.3
1.6
—
—
—
0
0
44
456
0.96
0.06
1.5
1.6
16173.21
16131.54
e6/l
0.00
28
317
87
851
1.02
0.05
3.7
5.4
1.51
1.51
%
0.04
77
800
18
192
0.94
0.05
1.5
1.2
—
—
—
0
0
17
159
1.07
0.05
2.1
2.3
1329.12
884.89
mg
0.28
17
159
17
159
1.07
0.05
1.2
1.2
—
—
—
0
0
48
495
0.97
0.05
4.0
3.4
1.84
2.09
index
0.14
31
248
414
4111
1.01
0.05
4.3
4.2
87.88
85.84
%
0.89
407
4026
1089
10912
0.99
0.03
29.2
26.0
330.08
330.69
g/l
1.47
1078
10827
91
922
0.99
0.02
1.7
1.8
1.24
1.45
g/l
0.43
84
835
204
2027
1.01
0.02
1.3
1.3
—
—
—
0
0
15
143
1.05
0.01
1.2
1.5
—
—
—
0
0
15
143
1.05
0.01
1.4
1.2
—
—
—
0
0
414
4150
1.00
0.01
3.8
3.5
0.00
0.06
1.92
13
154
34
346
0.98
0.00
2.0
1.7
—
—
—
0
0
58
575
1.01
0.00
1.6
1.2
—
—
—
0
0
77
775
0.99
0.00
3.8
5.7
0.88
0.86
%
0.16
68
728
15
152
0.99
0.00
1.4
1.2
—
—
—
0
0
21
208
1.01
0.00
1.0
1.3
22.86
10.28
u/l
0.77
12
168
14
138
1.01
0.00
1.2
1.1
—
—
—
0
0
13
128
1.02
0.00
1.1
1.4
—
53.00
—
0
10
14
137
1.02
0.00
1.2
1.2
—
—
—
0
0
33
327
1.01
0.00
1.3
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
4.18
—
0
5
0
6
0.00
-0.00
0.0
2.0
—
32.67
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
59
1.02
-0.00
1.2
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.2
—
376.60
—
0
5
5
56
0.89
-0.00
1.0
1.1
—
—
—
0
0
5
52
0.96
-0.00
1.2
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
-0.00
1.6
1.8
0.00
0.00
estimate
—
5
52
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
7
78
0.90
-0.00
2.1
4.1
—
—
—
0
0
203
2030
1.00
-0.00
5.4
5.3
34.24
33.43
%
0.42
131
1263
9
95
0.95
-0.00
1.6
1.5
12.89
15.28
umol/l
—
9
87
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
0.16
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.0
—
10.83
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
0.05
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
2.38
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
90
1.00
-0.00
3.3
1.8
15.33
16.32
%
—
9
84
0
5
0.00
-0.00
0.0
1.8
—
351.00
—
0
5
9
93
0.97
-0.00
1.2
1.7
124.33
85.43
umol/l
—
9
93
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
160.00
—
0
5
70
700
1.00
-0.00
2.3
3.3
82.53
2305.78
u/ml
0.93
54
608

Mortality – FinRegistry

↥

Association

Association between endpoint H7_GLAUCCLOSEPRIM and mortality.

Females

Parameter HR [95% CI] p-value
H7_GLAUCCLOSEPRIM 1.071 [0.99, 1.16] 0.085
Birth year 0.992 [0.98, 1.0] 0.045

During the follow-up period (1.1.1998 — 31.12.2019), 2692 out of 7308 females with H7_GLAUCCLOSEPRIM died.

Males

Parameter HR [95% CI] p-value
H7_GLAUCCLOSEPRIM 1.093 [0.98, 1.22] 0.115
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 1312 out of 3811 males with H7_GLAUCCLOSEPRIM died.

Mortality risk

Mortality risk for people of age

years, who have H7_GLAUCCLOSEPRIM.

N-year risk Females Males
1 0.064% 0.193%
5 0.526% 1.222%
10 1.319% 3.23%
15 2.475% 5.968%
20 4.646% 9.811%

Relationships between endpoints

↥

Index endpoint: H7_GLAUCCLOSEPRIM – Primary angle-closure glaucoma

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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