Venous complications and haemorrhoids in the puerperium

O15_VENOUS_COMPLIC

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

only females

313377

2. Check conditions

None

313377

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O87
  • Hospital discharge: ICD-9 671
  • Hospital discharge: ICD-8 671
  • Cause of death: ICD-10 O87
  • Cause of death: ICD-9 671
  • Cause of death: ICD-8 671

2 out of 7 registries used, show all original rules.

444

4. Check minimum number of events

None

444

5. Include endpoints

None

444

6. Filter based on genotype QC (FinnGen only)

410

Control definitions (FinnGen only)

Control exclude
O15_COMPLIC_PUERP

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5
Parent code in ICD-10
O85-O92
Name in latin
Complicationes venosae in puerperio

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2932 2932 -
Only index persons 2824 2824 -
Unadjusted period prevalence (%)
Whole population 0.08 0.08 -
Only index persons 0.10 0.10 -
Median age at first event (years)
Whole population - 31.39 -
Only index persons - 31.32 -

-FinnGen-

Key figures

All Female Male
Number of individuals 410 410 -
Unadjusted period prevalence (%) 0.15 0.15 -
Median age at first event (years) 30.90 30.90 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
417
Matched controls
4170
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
67100
ICD-8 Finland
Puerperal phlebitis and thrombosis, Thrombophlebitis extremitatis inferioris
+∞
103.6
95
*
O87.0
ICD-10 Finland
Superficial thrombophlebitis in the puerperium
+∞
78.7
73
*
I83.9
ICD-10 Finland
Varicose veins of lower extremities without ulcer or inflammation
5.4
51.4
129
319
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
5.0
43.0
113
287
6712B
ICD-9 Finland
Venous complications in pregnancy and the puerperium, Superficial thrombophlebitis[THROMBOPHLEB SUPERFIC EXTR INF,PUERP AIKANA]
+∞
40.3
38
*
PHD99
NOMESCO Finland
Resection of other vein
5.7
39.9
86
183
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
4.6
38.4
115
322
45499
ICD-8 Finland
Varicose veins of lower extremities, Other and unspecified, without ulcer
7.7
38.4
58
86
O87.1
ICD-10 Finland
Deep phlebothrombosis in the puerperium
+∞
37.0
35
*
B01AB05
ATC
enoxaparin; parenteral
3.6
36.4
209
913
I80.0
ICD-10 Finland
Phlebitis and thrombophlebitis of superficial vessels of lower extremities
7.5
35.8
55
83
B01AA03
ATC
warfarin; systemic
4.8
34.3
89
221
O87.2
ICD-10 Finland
Haemorrhoids in the puerperium
+∞
33.8
32
*
B01AB04
ATC
dalteparin; parenteral
7.2
33.3
53
83
PHD76
NOMESCO Finland
Resection of long saphenous vein
6.0
32.9
64
123
4549X
ICD-9 Finland
Varicose veins of lower extremities, Without mention of ulcer or inflammation
6.2
32.5
61
113
67101
ICD-8 Finland
Puerperal phlebitis and thrombosis, Thrombosis extremitatis inferioris
+∞
23.1
22
*
5611
FHL
Vena saphena Magna and / or swarm of nodule and possible local emissions
5.3
21.9
47
98
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
6.3
21.8
38
65
6718B
ICD-9 Finland
Venous complications in pregnancy and the puerperium, Other venous complications[HAEMORRHOIDES ANI,PUERP AIKANA]
+∞
21.0
20
*
6715A
ICD-9 Finland
Venous complications in pregnancy and the puerperium, Other phlebitis and thrombosis[PHLEBITIS/THROMBOSIS ALIA,RASKAUDEN AIKANA]
+∞
17.8
17
*
6714A
ICD-9 Finland
Venous complications in pregnancy and the puerperium, Deep phlebothrombosis, postpartum[THROMBOPHLEB PROF EXTR INFER,RASKAUDEN AIKANA]
+∞
15.7
15
*
6712A
ICD-9 Finland
Venous complications in pregnancy and the puerperium, Superficial thrombophlebitis[THROMBOPHLEB SUPERFIC EXTR INF,RASKAUDEN AIKANA]
+∞
15.7
15
*
379
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism
6.3
14.5
25
42
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
2.9
14.4
76
296
PHM76
NOMESCO Finland
Endovenous obliteration of v.saphena magna
3.8
13.5
43
122
4511A
ICD-9 Finland
Phlebitis and thrombophlebitis, Of deep vessels of lower extremities
51.7
12.9
15
*
O87.3
ICD-10 Finland
Cerebral venous thrombosis in the puerperium
+∞
12.6
12
*
6714B
ICD-9 Finland
Venous complications in pregnancy and the puerperium, Deep phlebothrombosis, postpartum[THROMBOPHLEB PROF EXTR INFER,PUERP AIKANA]
+∞
12.6
12
*
B01AB01
ATC
heparin; parenteral
+∞
11.5
11
*
6718A
ICD-9 Finland
Venous complications in pregnancy and the puerperium, Other venous complications[HAEMORRHOIDES ANI,RASKAUDEN AIKANA]
+∞
11.5
11
*
5612
FHL
Local excisions and / or perforations of relapsing varicose veins
8.9
10.7
22
26
6500B
ICD-9 Finland
Delivery in a completely normal case[PARTUS SINE COMPLICATIONE]
2.1
10.6
134
767
I83.1
ICD-10 Finland
Varicose veins of lower extremities with inflammation
9.4
9.6
19
21
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
2.4
9.1
66
298
PHM99
NOMESCO Finland
Endovenous obliteration of other vein
4.1
8.4
23
58
6715B
ICD-9 Finland
Venous complications in pregnancy and the puerperium, Other phlebitis and thrombosis[PHLEBITIS/THROMBOSIS ALIA,PUERP AIKANA]
+∞
8.4
8
*
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
2.0
8.3
103
578
65000
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
1.9
8.0
155
1009
O60
ICD-10 Finland
Preterm labour and delivery
4.0
7.8
22
57
V230A
ICD-9 Finland
Supervision of high-risk pregnancy, Pregnancy with history of infertility
6.6
7.8
19
30
I82.9
ICD-10 Finland
Embolism and thrombosis of unspecified vein
8.3
7.7
16
20
O87.9
ICD-10 Finland
Venous complication in the puerperium, unspecified
+∞
7.3
7
*
67000
ICD-8 Finland
Sepsis of childbirth and the puerperium, Endometritis
+∞
7.3
7
*
I83
ICD-10 Finland
Varicose veins of lower extremities
3.6
7.2
24
70
O22.0
ICD-10 Finland
Varicose veins of lower extremity in pregnancy
30.6
7.2
9
*
OAA11, ,
SPAT
2.6
7.1
43
178
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
2.8
7.0
35
131
W84
ICPC
Pregnancy high risk
3.0
7.0
31
109
SPAT1249
SPAT
Treatment-related counselling outside office
1.7
6.9
179
1258
OAA12, ,
SPAT
2.8
6.9
34
127
WZC00, ,
SPAT
2.1
6.8
74
394
SPAT1197
SPAT
Extensive health check-up of expecting family
2.0
6.6
83
465
KMAK, ,
NOMESCO Finland
1.7
6.5
246
1908
O80.8
ICD-10 Finland
Other single spontaneous delivery
2.7
6.5
35
137
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
2.1
6.3
67
353
45100
ICD-8 Finland
Phlebitis and thrombophlebitis, Of lower extremities
27.1
6.2
8
*
SPAT1379
SPAT
Health check-up of pregnant person
2.0
6.2
71
385
SAA01
NOMESCO Finland
Simple examination of mouth
1.9
6.2
330
2800
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.7
6.0
218
1659

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
27
56
5.09
12.55
1.2
1.2
—
—
—
0
0
232
1605
2.00
10.86
4.0
3.4
7.97
0.05
estimate
0.49
63
362
44
151
3.14
10.27
1.7
1.7
21.00
20.23
s
0.25
34
133
174
1137
1.91
9.18
4.2
3.8
0.00
0.01
estimate
1.08
71
418
27
73
3.89
9.04
1.2
1.2
2.75
5.96
u/ml
0.43
12
28
149
930
1.94
8.99
2.1
1.8
2.15
1.01
mg/l
0.92
117
727
273
2126
1.82
7.66
4.2
3.6
0.00
0.00
estimate
0.50
72
431
276
2163
1.82
7.51
4.1
3.7
13.16
0.02
estimate
0.49
76
419
203
1464
1.75
7.28
21.7
9.2
1.29
1.11
inr
3.82
176
1172
272
2152
1.76
6.84
4.1
3.7
0.00
3.44
estimate
0.50
74
438
68
363
2.04
6.21
2.0
1.6
833.06
982.71
mu/l
0.86
59
301
88
524
1.86
5.83
2.0
1.8
—
—
—
0
0
81
475
1.88
5.61
2.4
1.9
29.26
29.00
s
0.18
76
464
171
1246
1.63
5.44
3.4
3.3
13.89
80.93
ng/l
0.69
102
766
412
3925
5.14
5.35
18.6
16.6
66.03
67.60
umol/l
1.26
412
3879
164
1193
1.62
5.20
3.6
3.1
0.75
0.03
estimate
0.49
69
360
403
3744
3.28
5.06
15.4
14.4
139.95
139.80
mmol/l
0.82
397
3665
403
3752
3.21
4.88
15.5
14.5
3.94
3.92
mmol/l
0.86
396
3660
60
336
1.92
4.76
4.1
3.5
—
—
—
0
0
401
3729
2.96
4.76
16.1
13.1
20.10
20.17
mg/l
0.02
346
2985
218
1725
1.55
4.67
3.7
3.3
6.31
6.21
ph
0.68
134
968
256
2101
1.57
4.64
3.9
4.2
6.21
6.41
mmol/l
1.21
236
1935
16
51
3.22
4.25
1.9
2.0
—
—
—
0
0
41
212
2.04
4.08
1.8
1.6
54.99
60.85
ug/l
0.42
34
178
124
920
1.50
3.34
4.2
3.6
1.02
1.02
kg/l
0.80
81
611
107
771
1.52
3.31
2.5
2.5
7.61
9.08
e6/l
0.33
93
702
224
1863
1.44
3.31
3.1
2.6
—
—
estimate
—
0
0
210
1727
1.44
3.29
10.9
9.8
0.00
0.00
e9/l
0.30
187
1407
157
1228
1.45
3.21
2.8
2.7
—
—
—
0
0
143
1112
1.44
2.97
2.3
2.0
146.05
145.32
u/l
0.01
136
1058
149
1179
1.41
2.78
2.8
2.4
54.06
61.72
u/l
0.82
141
1089
47
291
1.69
2.71
2.6
2.9
1.23
1.24
mmol/l
0.17
39
253
19
87
2.24
2.61
2.5
2.3
3.61
4.79
umol/l
0.65
14
58
85
615
1.48
2.54
2.2
1.8
—
—
—
0
0
353
3265
1.53
2.52
5.7
5.0
14.59
14.57
pmol/l
0.05
333
3061
6
177
0.33
2.46
2.3
2.3
—
—
—
0
0
60
407
1.55
2.42
1.4
1.6
—
—
—
0
0
237
2055
1.36
2.41
5.9
6.0
1.88
1.99
e9/l
0.86
223
1832
109
835
1.41
2.40
2.0
1.7
—
—
—
0
0
404
3882
2.31
2.39
15.6
11.8
—
—
—
0
0
156
1274
1.36
2.33
4.8
6.0
—
—
—
0
0
386
3664
1.72
2.25
6.7
6.1
1.70
1.81
mu/l
1.53
372
3462
186
1567
1.34
2.24
4.7
4.3
36.12
36.64
g/l
0.68
174
1479
314
2863
1.39
2.22
8.0
7.5
74.98
76.85
u/l
0.51
303
2709
8
24
3.38
2.19
1.4
1.3
—
—
—
0
0
230
2006
1.33
2.15
5.9
6.0
0.52
0.53
e9/l
0.40
214
1741
114
897
1.37
2.13
1.9
2.5
309.16
311.24
umol/l
0.07
104
801
38
239
1.65
2.10
3.0
2.1
17124.03
6645.09
u/l
0.97
24
110
230
2012
1.32
2.08
6.0
6.0
0.04
0.04
e9/l
0.44
214
1748
407
3945
2.32
1.94
12.5
11.2
23.29
24.00
u/l
0.58
398
3852
8
27
3.00
1.94
1.3
1.3
—
—
—
0
0
49
339
1.50
1.83
2.2
2.1
6.12
6.14
ph
0.06
30
219
5
12
4.20
1.83
1.0
1.3
27.00
29.92
s
—
5
12
118
955
1.33
1.81
3.8
3.6
—
0.20
—
0
5
235
2088
1.29
1.78
5.9
6.3
0.18
0.18
e9/l
0.13
219
1842
14
67
2.13
1.78
4.0
3.2
3.88
4.72
e9/l
0.78
14
67
0
49
0.00
1.69
0.0
1.6
—
84.32
—
0
49
6
19
3.19
1.66
1.8
1.4
66.17
70.21
umol/l
—
6
19
29
184
1.62
1.59
2.3
1.8
—
—
—
0
0
120
991
1.30
1.58
5.1
4.3
—
—
—
0
0
26
161
1.66
1.56
2.0
1.6
—
—
—
0
0
28
178
1.61
1.53
1.9
1.8
—
—
—
0
0
13
65
2.03
1.50
1.2
1.2
—
—
—
0
0
25
156
1.64
1.47
1.8
1.5
1.20
1.30
mm
0.65
17
110
5
16
3.15
1.44
1.4
1.8
137.00
141.94
nmol/l
—
5
16
193
1704
1.25
1.44
1.9
2.1
—
—
—
0
0
41
289
1.46
1.43
2.5
3.0
7.37
7.38
ph
0.33
23
161
45
324
1.44
1.41
2.1
3.1
1.56
1.83
%
1.82
38
295
135
1151
1.26
1.35
2.8
3.0
19.87
53.98
e6/l
1.45
104
842
84
675
1.31
1.35
1.4
1.4
617.14
606.30
titre
0.01
21
146
118
995
1.26
1.30
2.6
2.8
0.12
0.42
e6/l
3.88
91
691
244
2231
1.23
1.25
7.7
9.0
4.08
3.91
e9/l
0.42
226
1957
112
943
1.26
1.24
3.7
3.3
95.19
97.62
%
0.41
103
919
204
1834
1.22
1.23
6.1
6.2
8.30
8.42
%
0.28
191
1714
364
3487
1.35
1.22
5.7
5.8
38.31
38.26
mmol/mol
0.04
347
3306
24
157
1.56
1.20
1.9
1.5
—
—
—
0
0
204
1838
1.22
1.19
6.1
6.1
2.72
2.80
%
0.25
190
1716
44
328
1.38
1.16
4.8
4.6
0.08
0.20
%
0.40
12
71
5
20
2.52
1.15
1.2
1.7
77.20
82.34
ng/l
—
5
20
35
251
1.43
1.15
1.2
1.2
—
—
—
0
0
98
820
1.26
1.15
3.5
3.6
—
—
—
0
0
210
1904
1.21
1.13
2.6
2.6
77.26
78.18
nmol/l
0.17
201
1749
140
1222
1.22
1.11
2.1
1.6
—
—
—
0
0
114
974
1.23
1.11
1.5
1.4
28.75
28.18
iu/ml
0.02
37
309
79
649
1.27
1.08
2.7
2.4
488.55
491.45
mosm/kgh2o
0.03
65
565
206
1874
1.20
1.04
6.1
6.1
29.33
29.57
%
0.11
196
1773
39
291
1.38
1.04
2.5
3.0
6.11
5.79
kpa
1.17
39
282
202
1835
1.20
1.04
6.1
6.1
0.73
0.71
%
0.15
188
1707
7
34
2.08
1.03
1.1
1.0
—
—
—
0
0
10
53
1.91
1.02
1.4
1.2
—
—
—
0
0
16
99
1.64
1.01
1.4
1.4
0.21
0.37
nmol/l
1.32
11
83
9
159
0.56
1.00
1.2
1.1
1.50
1.62
g/l
—
9
159
28
199
1.44
0.98
1.9
1.8
2.32
5.31
iu/ml
—
9
41
18
116
1.58
0.98
3.8
4.0
—
—
—
0
0
230
2122
1.19
0.97
3.4
3.2
87.95
76.67
ug/l
0.53
217
2001
13
77
1.71
0.96
1.1
1.1
2.65
0.95
u/ml
—
5
29
64
523
1.26
0.92
1.7
1.6
1222.15
1174.78
nmol/l
0.17
55
392
157
1408
1.18
0.91
3.2
3.7
54.92
65.68
e6/l
0.17
116
899
32
238
1.37
0.89
5.0
7.3
7.66
8.15
mmol/l
0.17
32
231
14
87
1.63
0.88
4.1
3.2
55.00
58.56
%
0.48
14
87
374
3629
1.30
0.86
5.1
4.8
5.71
5.77
mmol/l
0.54
352
3393
13
80
1.65
0.85
1.1
1.1
1.28
1.81
u/ml
—
5
39
48
383
1.29
0.84
2.0
2.1
0.10
0.07
estimate
—
10
76
8
45
1.79
0.84
1.5
1.3
—
—
—
0
0
140
1251
1.18
0.84
2.3
2.1
—
—
—
0
0
214
1979
1.17
0.84
6.2
5.8
10.34
10.03
umol/l
0.14
202
1884
197
1811
1.17
0.83
4.9
6.2
1.23
1.22
mmol/l
0.44
169
1550
21
147
1.45
0.82
2.0
1.8
5.48
3.53
iu/l
0.24
11
59
42
333
1.29
0.78
4.9
4.3
1.36
0.97
%
0.17
11
88
149
1346
1.17
0.78
3.5
3.2
2.35
2.37
mmol/l
0.51
139
1233
13
83
1.58
0.75
1.0
1.3
—
—
—
0
0
5
24
2.10
0.74
1.8
2.1
6.06
6.66
mmol/l
—
5
17
27
202
1.36
0.74
1.4
1.2
4.76
0.85
u/ml
—
5
14
253
2671
0.87
0.73
3.6
3.1
36.05
39.76
u/l
0.54
241
2539
66
558
1.22
0.72
1.2
1.2
—
—
—
0
0
12
76
1.60
0.72
1.1
2.7
1.17
1.39
ratio
—
7
43
131
1179
1.16
0.71
4.6
6.0
—
—
—
0
0
40
320
1.28
0.71
2.8
3.6
7.40
7.36
ph
2.34
29
210
39
311
1.28
0.71
1.4
1.3
33.25
28.69
iu/l
0.36
34
267
64
542
1.21
0.69
2.0
1.5
—
—
—
0
0
26
339
0.75
0.69
1.5
1.3
—
—
—
0
0
5
27
1.86
0.68
8.0
2.4
20.00
28.12
mg/l
—
5
17
111
990
1.17
0.68
2.3
2.2
2.84
2.75
mg/l
0.17
102
865
106
942
1.17
0.68
2.3
2.0
—
—
—
0
0
11
166
0.65
0.66
7.6
8.1
15.61
15.80
%
0.09
11
160
365
3552
1.22
0.65
4.2
4.0
1.19
1.22
mmol/l
0.49
348
3315
10
62
1.63
0.65
3.1
3.9
—
—
—
0
0
17
120
1.43
0.65
2.9
3.4
3665.29
356.61
mg/l
—
7
38
30
234
1.30
0.65
1.6
3.1
67.99
76.34
e9/l
0.89
23
166
26
199
1.33
0.64
1.8
2.2
0.25
0.02
estimate
—
8
65
39
316
1.26
0.64
5.2
4.4
0.38
0.10
%
—
8
71
11
163
0.67
0.61
1.2
1.2
1.04
0.89
g/l
0.75
11
163
0
21
0.00
0.60
0.0
1.5
—
46.80
—
0
21
23
175
1.33
0.59
3.2
3.7
5.29
5.20
kpa
0.21
23
169
24
184
1.32
0.59
2.5
2.4
132.58
128.83
g/l
0.40
24
179
27
211
1.30
0.58
1.1
1.1
—
—
—
0
0
25
319
0.77
0.58
1.2
1.3
—
—
—
0
0
0
23
0.00
0.58
0.0
16.8
—
811.48
—
0
23
14
98
1.44
0.57
1.3
1.1
—
—
—
0
0
14
98
1.44
0.57
1.3
1.1
—
—
—
0
0
20
150
1.35
0.57
1.6
1.5
1.16
1.21
g/l
0.29
20
144
39
322
1.23
0.56
4.8
4.2
1.14
0.70
%
0.37
11
81
6
37
1.63
0.55
1.3
1.1
186.33
200.10
mg/l
—
6
31
31
249
1.26
0.55
2.4
2.5
3.93
4.51
kpa
1.45
31
243
9
60
1.51
0.54
1.1
1.1
—
0.02
—
0
18
58
500
1.19
0.54
2.1
2.0
—
—
—
0
0
18
134
1.36
0.54
1.3
1.2
—
—
—
0
0
19
143
1.34
0.53
1.7
1.5
0.22
0.24
g/l
0.54
19
138
14
192
0.72
0.53
1.4
1.4
—
—
—
0
0
6
39
1.55
0.53
1.0
2.1
18.65
24.93
ng/l
—
6
39
14
191
0.72
0.52
1.4
1.4
—
—
—
0
0
6
40
1.51
0.52
1.7
1.2
29.50
27.08
mg/l
—
6
32
14
101
1.40
0.50
4.9
6.9
—
—
—
0
0
382
3751
1.22
0.49
4.9
4.8
1.54
1.58
mmol/l
1.31
366
3531
14
189
0.73
0.49
1.4
1.4
—
—
—
0
0
14
189
0.73
0.49
1.4
1.4
—
—
—
0
0
12
166
0.71
0.48
1.6
1.3
—
—
—
0
0
383
3763
1.22
0.48
5.1
4.9
4.80
4.86
mmol/l
0.56
363
3559
67
594
1.15
0.46
2.3
2.4
100.97
109.19
ug/g
0.13
54
460
44
378
1.18
0.44
1.0
1.2
—
—
—
0
0
5
31
1.62
0.43
1.6
1.2
75.94
28.38
nmol/l
—
5
25
385
3791
1.20
0.42
5.6
5.5
2.87
2.83
mmol/l
0.44
369
3579
15
114
1.33
0.41
1.4
1.2
3.28
3.69
mmol/l
1.18
15
107
0
16
0.00
0.41
0.0
1.8
—
79.00
—
0
16
13
97
1.35
0.40
1.4
1.3
—
—
—
0
0
52
458
1.15
0.40
1.3
1.3
—
—
—
0
0
57
506
1.15
0.39
1.3
1.3
—
—
—
0
0
122
1135
1.11
0.39
3.0
3.7
7.39
7.40
ph
0.54
98
790
5
35
1.43
0.39
1.4
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
1.8
—
51.09
—
0
11
9
66
1.37
0.38
3.2
1.6
58.00
57.83
%
—
9
66
120
1118
1.10
0.38
1.2
1.3
1.24
2.19
u/ml
0.69
37
301
14
180
0.77
0.37
1.4
1.4
—
—
—
0
0
17
134
1.28
0.37
1.1
1.2
—
—
—
0
0
26
310
0.83
0.37
1.4
1.8
—
—
—
0
0
9
122
0.73
0.35
1.3
1.8
—
—
—
0
0
28
328
0.84
0.34
1.2
1.4
—
—
—
0
0
80
735
1.11
0.33
3.9
2.4
2.44
2.45
mmol/l
0.02
72
668
82
755
1.11
0.33
1.7
1.6
423.04
28903067.63
pmol/l
1.06
67
647
13
101
1.30
0.32
1.0
1.0
—
—
—
0
0
126
1335
0.92
0.31
3.8
2.8
26.99
28.28
u/l
0.45
118
1265
19
229
0.82
0.31
1.1
1.1
—
—
—
0
0
12
153
0.78
0.31
1.3
1.4
—
—
—
0
0
111
1041
1.09
0.31
1.8
1.6
21.01
21.73
nmol/l
0.19
95
899
38
428
0.88
0.29
1.3
1.3
—
—
—
0
0
7
57
1.23
0.29
1.4
1.1
—
—
—
0
0
8
62
1.30
0.28
2.3
2.4
—
—
—
0
0
23
196
1.18
0.27
1.2
1.3
206.11
227.30
miu/ml
0.09
13
95
35
312
1.13
0.25
2.8
2.5
13.02
17.72
au/ml
—
5
33
96
905
1.08
0.24
1.4
1.3
5.71
10.60
u/ml
0.90
54
364
13
158
0.82
0.24
1.3
1.5
0.19
0.29
mg/l
—
5
59
5
38
1.32
0.23
1.0
1.0
—
—
—
0
0
5
40
1.25
0.22
1.4
1.1
98.20
114.83
pmol/l
—
5
40
5
40
1.25
0.22
1.0
2.0
33.20
31.98
pg
—
5
40
5
40
1.25
0.22
1.8
3.2
—
—
—
0
0
5
41
1.22
0.22
1.2
1.2
—
—
—
0
0
10
124
0.80
0.22
1.6
1.8
—
—
—
0
0
44
402
1.11
0.22
1.3
1.2
77.17
160.77
u/ml
1.54
15
170
36
325
1.12
0.22
2.9
2.2
0.22
0.22
g/l
0.04
36
309
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
2.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
15
177
0.84
0.21
8.7
7.3
23.34
25.07
mmol/l
1.34
15
170
0
12
0.00
0.21
0.0
2.6
—
0.61
—
0
12
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
9.5
—
97.57
—
0
7
19
164
1.17
0.20
2.8
2.2
0.54
0.60
%
0.50
19
164
13
108
1.21
0.20
1.3
1.2
21.57
9.51
e6/l
—
7
77
0
14
0.00
0.20
0.0
1.9
—
0.48
—
0
14
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
6
49
1.23
0.20
1.8
1.2
577.67
361.54
pmol/l
—
6
44
19
166
1.15
0.18
2.8
2.2
1.32
1.17
%
0.20
19
166
24
214
1.13
0.18
1.3
2.0
—
—
—
0
0
5
66
0.75
0.17
1.0
2.5
8.86
8.26
kpa
—
5
66
8
70
1.15
0.16
1.3
1.5
—
—
—
0
0
175
1704
1.05
0.15
2.0
1.9
1.35
1.33
mmol/l
0.13
140
1460
167
1625
1.05
0.15
4.7
5.5
1.23
1.22
mmol/l
0.62
158
1503
54
508
1.07
0.15
1.5
1.5
—
—
—
0
0
113
1090
1.05
0.15
2.7
3.4
42.80
34.62
mg/l
0.20
61
640
45
421
1.08
0.14
1.4
2.2
8.50
5.26
umol/l
0.39
36
365
43
402
1.08
0.14
5.3
5.9
104.60
104.32
mmol/l
0.18
43
402
114
1103
1.05
0.13
3.3
4.1
10.53
7.09
mg/mmol
0.25
68
619
9
108
0.83
0.13
2.1
1.6
15.47
1.31
ug/l
—
9
100
124
1203
1.04
0.13
2.6
3.2
6.54
6.97
mmol/l
0.56
112
1024
30
323
0.92
0.12
5.3
7.3
1.48
1.15
mmol/l
0.14
25
274
33
353
0.93
0.11
2.4
2.3
41.79
39.03
u/l
0.07
28
288
14
125
1.12
0.10
1.5
1.3
500.00
438.03
mg/l
0.25
14
119
31
330
0.93
0.10
5.7
7.3
12.82
12.79
kpa
0.01
31
320
31
330
0.93
0.10
5.7
7.3
5.31
5.19
kpa
0.28
31
320
36
340
1.06
0.09
1.4
1.3
157.55
199.13
u/ml
0.14
31
319
54
518
1.05
0.09
1.2
1.2
—
—
—
0
0
165
1621
1.03
0.09
2.0
2.0
103.80
99.31
pmol/l
0.56
95
804
166
1632
1.03
0.08
3.2
2.9
—
—
—
0
0
7
66
1.06
0.08
1.7
1.7
—
—
—
0
0
26
245
1.07
0.07
4.2
7.2
—
—
—
0
0
8
78
1.03
0.07
1.8
2.4
6.27
6.58
pmol/l
—
8
78
7
81
0.86
0.07
1.6
2.4
0.63
0.83
nmol/l
—
7
67
31
326
0.95
0.07
5.7
7.4
7.40
7.42
ph
0.75
18
186
9
86
1.05
0.07
3.1
2.0
5.14
4.79
mmol/24h
—
9
77
11
120
0.91
0.05
1.2
2.8
13.65
10.80
mg/l
1.07
11
113
16
170
0.94
0.04
1.2
1.2
—
—
—
0
0
67
659
1.02
0.03
3.7
3.6
854.50
281.09
ng/l
0.40
48
440
13
122
1.07
0.02
1.1
1.2
—
—
—
0
0
42
411
1.02
0.02
1.4
1.5
—
—
—
0
0
40
392
1.02
0.01
1.4
1.7
3.59
3.45
mmol/l
0.26
21
283
96
951
1.01
0.01
1.3
1.4
2.21
2.20
g/l
0.02
61
580
49
497
0.98
0.01
2.1
2.4
22.27
23.02
%
0.17
44
463
54
547
0.99
0.01
2.1
2.7
3.37
4.26
e6/l
0.29
29
227
14
146
0.96
0.00
1.3
1.6
—
10.92
—
0
5
13
127
1.02
0.00
1.3
1.3
—
—
—
0
0
12
124
0.97
0.00
1.2
1.1
—
—
—
0
0
16
164
0.97
0.00
1.5
1.6
10.38
9.07
u/ml
—
5
34
5
52
0.96
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
226.90
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
1.57
—
0
7
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
64
0.94
-0.00
1.3
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
6
66
0.91
-0.00
1.0
2.3
—
—
—
0
0
5
59
0.85
-0.00
1.0
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
6.75
—
0
8
0
9
0.00
-0.00
0.0
1.2
—
0.03
—
0
9
0
9
0.00
-0.00
0.0
1.9
—
25.78
—
0
9
7
71
0.99
-0.00
1.0
1.1
—
—
—
0
0
9
92
0.98
-0.00
1.7
2.4
—
—
—
0
0
5
54
0.93
-0.00
1.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint O15_VENOUS_COMPLIC and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_VENOUS_COMPLIC.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: O15_VENOUS_COMPLIC – Venous complications and haemorrhoids in the puerperium

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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