Melanoma in situ of upper limb, including shoulder

CD2_INSITU_MELANOMA_UPPERLIMB

melanoma: A malignant, usually aggressive tumor composed of atypical, neoplastic melanocytes. Most often, melanomas arise in the skin (cutaneous melanomas) and include the following histologic subtypes: superficial spreading melanoma, nodular melanoma, acral lentiginous melanoma, and lentigo maligna melanoma. Cutaneous melanomas may arise from acquired or congenital melanocytic or dysplastic nevi. Melanomas may also arise in other anatomic sites including the gastrointestinal system, eye, urinary tract, and reproductive system. Melanomas frequently metastasize to lymph nodes, liver, lungs, and brain.

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D03.6&
  • Cause of death: ICD-10 D03.6&

2 out of 7 registries used, show all original rules.

305

4. Check minimum number of events

None

305

5. Include endpoints

None

305

6. Filter based on genotype QC (FinnGen only)

280

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D03
Name in latin
Melanoma in situ regionis deltoideae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 280 165 115
Unadjusted period prevalence (%) 0.06 0.06 0.05
Median age at first event (years) 69.03 67.72 70.91

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
289
Matched controls
2890
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
209.3
307.7
184
24
D03.6
ICD-10 Finland
Melanoma in situ of upper limb, including shoulder
4503599627370496.0
307.7
288
*
D22.6
ICD-10 Finland
Melanocytic naevi of upper limb, including shoulder
49.2
98.9
59
15
8720/2-C44.9
ICD-O-3
Melanoma in situ of skin, NOS
227.1
94.6
93
6
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
13.4
82.0
91
96
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
15.6
80.9
79
68
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
9.9
74.3
109
166
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
14.4
71.2
72
65
L57.0
ICD-10 Finland
Actinic keratosis
6.8
53.3
114
253
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
8.2
53.2
85
139
R23.8
ICD-10 Finland
Other and unspecified skin changes
6.1
52.6
149
428
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
6.1
38.3
81
173
D22.7
ICD-10 Finland
Melanocytic naevi of lower limb, including hip
14.3
33.7
32
25
S82
ICPC
Naevus/mole
4.9
32.9
94
258
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
9.6
30.3
38
45
C43.62
ICD-10 Finland
Malignant melanoma of upper extremity including shoulder: 'superficial spreading' type
74.1
29.6
33
5
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
11.9
29.2
31
29
TQW99
NOMESCO Finland
Other minor procedure on skin
6.5
28.7
52
94
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
10.5
28.5
33
35
ZZR00
NOMESCO Finland
Flap of skin
10.7
27.3
31
32
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
5.2
27.0
65
153
S18
ICPC
Laceration/cut
3.8
24.9
205
1124
D22
ICD-10 Finland
Melanocytic naevi
7.2
23.2
37
58
ZXC50
NOMESCO Finland
Cryotherapy
7.4
22.2
34
51
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
8.1
22.1
31
42
TQW40, ,
SPAT
4.1
19.6
63
184
8720/3-C44.9
ICD-O-3
Malignant melanoma, NOS, of skin, NOS
28.4
19.5
26
10
XQ848
NOMESCO Finland
Dermatological photography
7.8
19.4
28
39
L82
ICD-10 Finland
Seborrhoeic keratosis
3.3
19.3
103
419
D04.6
ICD-10 Finland
Carcinoma in situ: Skin of upper limb, including shoulder
37.2
19.2
24
7
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
4.6
18.6
50
127
D06BB10
ATC
imiquimod; topical
5.1
17.4
39
85
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
6.1
17.4
32
58
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
13.9
17.1
29
23
C43.60
ICD-10 Finland
Malignant melanoma of the upper extremity including the shoulder without histology
95.7
16.8
18
*
XQ846
NOMESCO Finland
Digital dermatoscopy and registration of nevi
180.0
16.7
17
*
8720/3-C44.6
ICD-O-3
Malignant melanoma, NOS, of skin of upper limb and shoulder
90.1
15.7
17
*
SPAT1153
SPAT
Removal of sutures
2.7
15.6
134
693
D03.5
ICD-10 Finland
Melanoma in situ of trunk
38.2
14.6
18
5
XQ845
NOMESCO Finland
Dermatoscopy
11.8
13.8
25
23
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
5.7
13.5
26
49
S77
ICPC
Malignant neoplasm of skin
16.1
13.3
21
14
C43.52
ICD-10 Finland
Malignant melanoma on the torso: 'superficial spreading' type
23.9
13.1
18
8
C43.6
ICD-10 Finland
Malignant neoplasm: Malignant melanoma of upper limb, including shoulder
52.5
13.0
15
*
8720/2-C44.6
ICD-O-3
Melanoma in situ of skin of upper limb and shoulder
+∞
12.6
12
*
C43.69
ICD-10 Finland
Malignant melanoma of the upper extremity including shoulder other or unspecified histology
67.8
11.7
13
*
8742/2-C44.9
ICD-O-3
Lentigo maligna of skin, NOS
24.1
11.7
16
7
D03.7
ICD-10 Finland
Melanoma in situ of lower limb, including hip
114.0
10.5
11
*
C43.72
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip: 'superficial spreading' type
33.9
10.4
13
*
D04.5
ICD-10 Finland
Carcinoma in situ: Skin of trunk
24.4
10.3
14
6
PJA12
NOMESCO Finland
Sentinel node biopsy
3.2
10.2
44
153
S29
ICPC
Skin symptom/complaint other
2.4
9.7
84
420
C43
ICD-10 Finland
Malignant melanoma of skin
31.2
9.5
12
*
QXE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in uspecified region
12.1
8.7
15
13
C43.59
ICD-10 Finland
Malignant melanoma of the trunk other or unspecified histology
20.8
8.5
12
6
C43.61
ICD-10 Finland
Malignant melanoma of the upper extremity including the shoulder originating in lentigo maligna
+∞
8.4
8
*
D04.4
ICD-10 Finland
Carcinoma in situ: Skin of scalp and neck
15.0
8.3
13
9
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
6.5
7.7
19
31
C43.50
ICD-10 Finland
Malignant melanoma of the torso without histology
25.8
7.6
10
*
PJ5AQ
NOMESCO Finland
Sentinell lymphnode SPECT with low dose CT
30.8
7.2
9
*
L01BC02
ATC
fluorouracil; systemic, topical
20.6
7.2
10
5
S21
ICPC
Skin texture symptom/complaint
2.3
7.1
61
300
QCA25
NOMESCO Finland
Destruction of lesion of skin of upper limb
14.2
6.9
11
8
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
6.4
6.9
17
28
QAE20
NOMESCO Finland
Excision and repair of scar or web of skin of head or neck
41.0
6.8
8
*
Z48.0
ICD-10 Finland
Attention to surgical dressings and sutures
4.2
6.7
18
45
8720/3-C44.5
ICD-O-3
Malignant melanoma, NOS, of skin of trunk
12.6
6.6
11
9
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
5.6
6.6
18
34
QDA25
NOMESCO Finland
Destruction of lesion of skin of lower limb
71.4
6.5
7
*
8743/3-C44.9
ICD-O-3
Low cumulative sun damage melanoma of skin, NOS
14.7
6.4
10
7
ZXC15
NOMESCO Finland
Use of photodynamic technique
6.8
6.4
15
23
D22.4
ICD-10 Finland
Melanocytic naevi of scalp and neck
8.4
6.4
13
16
127
Kela drug reimbursment
Transplant complication
11.4
6.3
11
10
L81.4
ICD-10 Finland
Other melanin hyperpigmentation
11.4
6.3
11
10
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
7.3
6.3
14
20
WX110
NOMESCO Finland
Infiltration anesthesia
2.0
6.3
208
1633
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
5.6
6.3
17
32
SPAT1141
SPAT
Excision of skin or mucous membrane lesion
3.3
6.0
23
74

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
162
357
9.05
80.45
2.3
1.3
—
—
—
0
0
241
1051
8.79
53.16
4.6
2.2
—
—
—
0
0
78
252
3.87
21.13
1.7
1.4
—
—
—
0
0
43
120
4.03
14.01
1.4
1.3
—
—
—
0
0
193
1409
2.11
8.13
8.6
7.3
1.22
1.21
mmol/l
0.72
168
1215
48
215
2.48
6.90
4.0
3.4
88.02
79.73
ng/l
0.20
35
186
51
235
2.42
6.89
3.7
4.2
7.39
7.36
ph
1.65
39
164
278
2453
4.50
6.66
6.6
6.2
2.68
2.62
mmol/l
0.52
244
2246
274
2401
3.72
6.52
5.9
5.3
1.51
1.49
mmol/l
0.33
238
2194
274
2411
3.63
6.26
5.9
5.4
4.65
4.56
mmol/l
0.66
241
2213
280
2561
4.00
5.94
15.1
12.6
24.12
24.54
u/l
0.21
271
2485
272
2397
3.29
5.91
6.2
5.5
5.79
6.01
mmol/l
2.62
231
2187
173
1296
1.83
5.84
8.5
6.5
1.22
1.21
mmol/l
0.49
160
1193
162
1204
1.79
5.48
3.0
2.5
82.74
78.96
nmol/l
1.13
138
1076
125
863
1.79
5.42
6.5
5.8
—
—
—
0
0
137
983
1.75
5.13
3.7
3.5
2.33
2.35
mmol/l
1.71
111
892
266
2353
2.64
5.04
7.5
6.9
38.43
39.77
mmol/mol
2.53
233
2199
141
1061
1.64
4.15
2.0
2.0
1.23
1.33
mmol/l
1.13
105
875
74
472
1.76
4.02
3.9
3.4
0.77
0.79
ug/l
0.07
47
306
257
2292
2.10
3.90
7.5
5.5
1.80
1.97
mu/l
1.81
235
2088
100
700
1.66
3.85
3.6
2.9
343.03
345.50
umol/l
0.10
91
610
209
1756
1.69
3.83
5.2
4.7
—
2.71
—
0
5
149
1157
1.59
3.72
13.1
12.3
0.00
0.00
e9/l
0.18
118
941
271
2480
2.49
3.65
17.2
15.5
—
—
—
0
0
274
2531
2.59
3.40
25.5
21.3
3.99
3.99
mmol/l
0.05
269
2480
256
2305
1.97
3.39
5.1
4.5
1.27
1.28
mmol/l
0.08
217
2084
179
1480
1.55
3.20
9.3
10.0
4.18
4.16
e9/l
0.03
145
1288
117
887
1.54
3.09
3.1
2.4
—
—
—
0
0
151
1218
1.50
2.93
7.0
5.9
59.08
57.67
%
0.89
144
1162
161
1316
1.50
2.93
7.0
5.9
0.60
0.58
e9/l
0.44
126
1119
149
1204
1.49
2.83
7.3
6.0
0.63
0.67
%
0.49
141
1126
201
1728
1.54
2.82
5.3
5.1
19.00
1639.95
e6/l
—
5
37
161
1325
1.49
2.78
7.0
5.9
0.04
0.04
e9/l
0.34
128
1125
227
2009
1.61
2.77
10.3
8.3
75.00
81.38
u/l
2.02
210
1898
149
1209
1.48
2.75
7.2
5.9
2.76
2.81
%
0.10
141
1135
165
1367
1.48
2.74
7.4
6.3
0.18
0.19
e9/l
0.38
130
1181
149
1212
1.47
2.70
7.3
6.1
9.00
8.93
%
0.13
140
1139
264
2438
1.96
2.69
20.3
17.6
21.36
24.31
mg/l
0.95
230
2043
67
461
1.59
2.66
4.8
3.3
0.84
0.81
mmol/l
0.87
60
437
162
1346
1.46
2.59
7.1
6.0
1.80
1.97
e9/l
0.85
130
1181
150
1229
1.46
2.58
7.3
6.0
26.24
26.92
%
0.37
143
1170
115
896
1.47
2.56
5.8
4.1
7.40
7.40
ph
0.58
85
634
149
1226
1.44
2.46
2.4
2.2
95.64
96.38
pmol/l
0.05
67
604
67
478
1.52
2.26
1.4
1.3
23.47
31.67
iu/ml
0.50
15
157
148
1230
1.42
2.25
3.3
2.9
—
—
estimate
—
0
0
48
320
1.60
2.17
1.2
1.3
—
—
—
0
0
9
31
2.96
2.09
1.0
2.1
—
—
—
0
0
148
1242
1.39
2.07
5.4
4.7
35.39
35.28
g/l
0.09
134
1173
48
324
1.58
2.06
2.0
1.5
—
—
—
0
0
8
27
3.02
1.95
2.0
1.6
—
—
—
0
0
8
27
3.02
1.95
1.8
1.9
—
—
—
0
0
214
1925
1.43
1.91
6.1
4.3
15.10
14.92
pmol/l
0.48
188
1744
106
859
1.37
1.77
1.9
1.8
23.97
21.51
nmol/l
0.63
79
708
8
30
2.71
1.73
1.3
1.0
—
—
—
0
0
13
62
2.15
1.68
2.5
2.6
55.77
60.95
%
1.25
13
62
10
41
2.49
1.66
2.3
2.9
3.86
4.95
e9/l
—
10
41
23
136
1.75
1.64
2.5
2.6
—
—
—
0
0
10
43
2.37
1.60
1.7
1.2
—
—
—
0
0
182
1617
1.34
1.59
4.0
3.3
45.65
48.95
u/l
0.27
166
1515
89
712
1.36
1.59
2.5
2.2
2.84
3.02
mg/l
0.29
66
617
57
424
1.43
1.55
1.4
1.3
11.40
10.94
u/ml
0.02
17
157
105
865
1.34
1.54
2.6
2.0
232.23
192.97
u/l
0.22
97
813
41
290
1.48
1.45
1.7
1.8
—
—
—
0
0
135
1162
1.30
1.43
3.9
3.0
170.94
126.75
ug/l
1.12
121
1071
11
53
2.12
1.40
4.6
2.5
—
—
—
0
0
106
886
1.31
1.38
2.9
3.3
—
—
—
0
0
98
811
1.32
1.37
6.6
6.6
—
—
—
0
0
23
144
1.65
1.37
1.4
2.1
1.22
1.50
g/l
0.66
18
128
0
37
0.00
1.35
0.0
2.8
—
1.19
—
0
37
0
38
0.00
1.35
0.0
2.8
—
106.11
—
0
38
0
38
0.00
1.35
0.0
2.8
—
3.98
—
0
38
96
796
1.31
1.32
7.2
5.8
8.37
2.40
ug/l
0.45
85
712
6
24
2.53
1.31
2.3
1.4
—
—
—
0
0
5
18
2.81
1.29
1.4
1.8
39.78
38.52
%
—
5
18
5
19
2.66
1.22
1.2
1.2
—
—
—
0
0
121
1045
1.27
1.20
5.5
4.1
64.80
95.12
e6/l
0.37
91
731
57
444
1.35
1.20
3.6
2.4
2.19
2.27
g/l
0.58
52
404
150
1330
1.27
1.19
24.6
14.4
1.40
1.26
inr
1.89
127
1092
52
400
1.37
1.18
2.6
2.1
—
—
—
0
0
94
793
1.27
1.11
4.0
3.2
0.97
0.50
e6/l
0.28
68
577
7
31
2.29
1.11
1.0
1.5
275.71
264.32
mosm/kgh2o
—
7
22
54
425
1.33
1.07
3.8
2.4
23.00
22.26
%
0.17
49
393
60
480
1.32
1.06
3.6
2.4
12.58
12.89
umol/l
0.13
53
442
11
60
1.87
1.04
6.4
2.5
10.49
8.37
pmol/l
0.24
11
60
5
23
2.19
0.98
1.6
1.7
6.92
8.20
mmol/l
—
5
23
107
929
1.24
0.98
4.4
3.4
35.51
115.50
e6/l
0.56
81
707
58
469
1.30
0.95
3.4
3.1
2.90
2.50
e6/l
0.15
28
225
6
28
2.17
0.92
1.2
1.5
28.92
33.11
ng/l
—
6
28
6
28
2.17
0.92
1.2
1.1
—
—
—
0
0
50
618
0.77
0.92
4.9
4.4
1.02
1.02
kg/l
0.21
37
410
8
43
1.88
0.88
3.1
1.3
—
—
—
0
0
6
30
2.02
0.87
1.2
1.2
—
—
—
0
0
24
171
1.44
0.86
3.0
2.8
7.41
7.42
ph
0.74
19
143
17
114
1.52
0.81
2.4
3.1
—
—
—
0
0
11
174
0.62
0.79
1.5
1.8
0.90
1.41
g/l
1.35
11
155
194
1816
1.21
0.77
4.7
4.4
—
0.17
—
0
6
9
53
1.72
0.76
1.1
1.2
7.90
8.81
u/l
—
9
42
5
24
2.10
0.75
2.0
2.5
—
—
—
0
0
6
106
0.56
0.74
2.5
4.3
39.43
30.70
mg/l
—
6
91
5
25
2.02
0.73
1.4
1.5
0.28
0.51
mmol/l
—
5
25
5
27
1.87
0.68
1.8
1.2
—
—
—
0
0
7
43
1.64
0.67
1.0
1.0
—
—
—
0
0
21
155
1.38
0.65
1.3
1.2
7.67
125.25
u/ml
—
6
59
71
616
1.20
0.64
3.0
2.9
2.45
2.46
mmol/l
0.25
62
554
45
373
1.24
0.63
1.2
1.2
—
—
—
0
0
70
608
1.20
0.63
2.8
1.7
0.88
1.41
mg/l
1.82
58
476
10
151
0.65
0.61
1.3
1.4
—
—
—
0
0
27
211
1.31
0.59
5.4
4.0
—
—
—
0
0
19
251
0.74
0.58
3.4
2.7
4.66
4.33
kpa
0.25
19
243
11
160
0.68
0.57
2.5
2.4
1.13
1.16
%
0.07
11
160
17
227
0.73
0.56
1.9
1.6
—
—
—
0
0
6
38
1.59
0.54
1.2
1.2
0.80
0.52
nmol/l
—
6
33
96
1056
0.86
0.54
4.4
4.1
0.03
0.02
estimate
0.14
30
241
11
156
0.69
0.51
2.5
2.4
0.48
0.62
%
1.04
11
156
169
1595
1.14
0.51
6.0
5.2
6.45
6.67
mmol/l
0.83
163
1520
7
106
0.65
0.49
2.4
4.3
55.04
114.58
mg/l
—
7
90
7
46
1.53
0.48
1.0
1.0
—
—
—
0
0
12
85
1.43
0.47
1.4
1.4
—
—
—
0
0
28
229
1.25
0.46
4.9
4.5
0.13
0.21
%
—
8
63
8
56
1.44
0.43
1.0
1.2
3.70
3.78
mmol/l
—
8
51
62
552
1.16
0.43
3.2
3.0
517.87
530.36
mosm/kgh2o
0.22
55
487
5
32
1.57
0.42
4.4
3.6
5.54
3.33
nmol/l
—
5
32
5
33
1.52
0.41
1.4
1.8
89.24
90.03
%
—
5
33
5
33
1.52
0.41
2.6
3.5
—
—
—
0
0
13
97
1.36
0.40
3.8
1.6
4.66
8.55
iu/ml
—
5
20
61
546
1.15
0.39
5.2
4.2
414.62
246.59
ng/l
0.30
53
456
101
936
1.12
0.38
3.2
3.3
2077.53
1308.13
ng/l
0.82
86
791
26
219
1.21
0.34
4.9
4.0
0.75
0.57
%
—
8
69
149
1418
1.10
0.34
4.5
4.1
33.23
5.49
estimate
0.38
39
296
6
45
1.34
0.34
1.2
1.4
—
—
—
0
0
73
794
0.89
0.34
5.4
4.3
0.00
0.01
estimate
0.50
34
261
155
1479
1.10
0.34
7.7
6.6
11.71
11.51
umol/l
0.05
146
1408
29
248
1.19
0.33
2.7
2.0
0.00
0.00
estimate
—
6
50
6
46
1.31
0.33
1.8
1.3
—
—
—
0
0
6
46
1.31
0.33
1.0
1.2
—
—
—
0
0
10
131
0.75
0.31
3.2
3.7
37.02
36.96
°c
—
10
131
7
52
1.35
0.31
1.7
1.1
—
—
—
0
0
29
250
1.18
0.31
14.4
8.6
—
—
—
0
0
147
1404
1.10
0.30
4.5
4.1
0.00
0.00
estimate
-0.00
36
289
14
111
1.27
0.30
1.5
1.8
1.81
3.74
ug/l
0.32
14
101
100
938
1.10
0.30
4.3
3.1
7.23
7.36
mmol/l
0.11
78
790
27
232
1.18
0.30
1.8
2.5
5.96
6.13
ph
0.31
14
160
7
56
1.26
0.29
1.6
1.3
—
—
—
0
0
97
910
1.10
0.29
4.2
3.2
30.49
45.66
mg/l
0.60
54
585
39
347
1.14
0.28
1.9
1.7
—
—
—
0
0
35
309
1.15
0.28
1.9
1.5
—
—
—
0
0
8
66
1.22
0.27
1.9
1.1
1.01
0.86
g/l
—
8
66
149
1430
1.09
0.27
4.4
4.2
0.00
0.01
estimate
0.50
38
271
12
95
1.27
0.26
2.8
3.2
140.80
182.57
mg/l
—
5
30
68
633
1.10
0.24
4.0
2.7
5.85
5.24
e6/l
0.11
62
582
55
507
1.10
0.24
2.0
1.7
1082.42
1218.43
nmol/l
0.60
34
375
5
38
1.32
0.23
2.0
2.7
—
—
—
0
0
5
39
1.29
0.23
3.8
1.5
—
—
—
0
0
5
39
1.29
0.23
3.8
1.5
—
—
—
0
0
5
39
1.29
0.23
3.8
1.5
—
—
—
0
0
5
39
1.29
0.23
3.8
1.5
—
—
—
0
0
37
334
1.12
0.23
1.4
1.4
700.00
490.24
titre
—
10
82
11
88
1.26
0.23
9.1
2.2
2.10
1.57
mg/l
0.91
11
73
64
597
1.09
0.22
1.3
1.2
0.85
1.36
u/ml
0.79
19
155
0
11
0.00
0.21
0.0
2.9
—
5.81
—
0
11
0
11
0.00
0.21
0.0
12.1
—
1124.64
—
0
11
8
104
0.76
0.21
1.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
4.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
167.12
—
0
12
25
221
1.14
0.21
5.3
4.1
0.14
0.17
%
—
7
64
0
13
0.00
0.21
0.0
1.7
—
—
—
0
0
37
337
1.11
0.20
11.4
8.9
2.15
0.72
mmol/l
1.11
29
282
98
935
1.07
0.20
5.4
3.8
8.66
8.19
mg/mmol
0.04
54
576
15
175
0.85
0.19
2.4
6.6
—
—
—
0
0
24
269
0.88
0.19
2.1
2.6
32.32
32.22
u/l
0.01
19
223
30
271
1.12
0.19
2.0
2.9
59.86
71.48
e9/l
1.94
19
198
60
563
1.08
0.18
2.0
1.8
435.30
25161741.42
pmol/l
0.50
41
465
7
58
1.21
0.18
1.9
3.1
30.29
36.80
umol/l
—
7
51
72
682
1.07
0.18
1.5
1.4
—
—
—
0
0
7
63
1.11
0.17
1.7
1.1
1.47
1.59
g/l
—
7
63
16
140
1.15
0.15
1.7
1.6
—
—
—
0
0
7
90
0.77
0.14
2.1
1.8
—
—
—
0
0
60
569
1.07
0.14
6.1
5.0
—
—
—
0
0
49
518
0.93
0.13
1.4
1.4
2.90
2.62
g/l
0.22
25
291
82
791
1.05
0.11
5.5
4.4
—
—
—
0
0
79
763
1.05
0.11
3.3
3.6
0.00
0.00
estimate
-0.00
30
229
34
320
1.07
0.10
2.6
3.3
5.41
4.83
e9/l
0.23
28
280
18
197
0.91
0.10
1.2
1.2
—
—
—
0
0
12
106
1.14
0.10
2.1
2.9
—
—
—
0
0
36
340
1.07
0.10
11.7
8.8
7.43
7.42
ph
0.28
18
193
15
135
1.12
0.10
1.7
1.3
—
—
—
0
0
30
282
1.07
0.09
2.8
3.3
2.47
1.84
mmol/l
0.40
25
239
27
253
1.07
0.09
1.9
1.5
—
—
—
0
0
6
56
1.07
0.08
1.7
3.9
20.33
29.40
u/ml
—
6
56
17
184
0.92
0.07
1.5
1.4
—
—
—
0
0
9
84
1.07
0.07
1.2
1.1
—
—
—
0
0
9
84
1.07
0.07
1.0
1.1
—
—
—
0
0
24
227
1.06
0.06
2.2
1.5
—
—
—
0
0
25
237
1.06
0.06
5.3
4.0
2.07
0.96
%
—
7
80
111
1126
0.98
0.04
4.4
3.7
6.08
6.22
ph
0.64
51
619
29
302
0.96
0.04
1.6
2.1
57.94
123.06
ug/g
1.70
22
236
32
332
0.96
0.04
3.8
4.5
3.50
27.94
ug/l
1.03
21
282
15
160
0.93
0.04
1.2
1.4
—
—
—
0
0
89
876
1.02
0.04
3.5
2.5
56.14
68.60
u/l
0.88
78
809
199
1979
1.02
0.02
26.7
23.4
331.50
331.29
g/l
0.12
199
1972
15
158
0.95
0.02
1.1
1.2
353.18
300.48
u/ml
0.06
15
147
20
208
0.96
0.02
1.5
2.5
—
—
—
0
0
10
93
1.08
0.02
1.2
1.2
—
—
—
0
0
90
892
1.01
0.01
3.8
3.5
—
—
—
0
0
109
1097
0.99
0.01
3.8
4.2
26.23
42.41
ng/l
1.38
81
824
11
116
0.95
0.00
2.5
1.9
—
—
—
0
0
37
364
1.02
0.00
2.7
2.8
1.59
1.84
%
1.37
31
327
29
288
1.01
0.00
2.9
3.4
6.32
5.74
kpa
1.39
29
281
17
169
1.01
0.00
1.4
1.3
—
—
—
0
0
30
297
1.01
0.00
2.9
3.4
7.36
7.38
ph
0.99
16
173
31
313
0.99
0.00
2.4
2.7
11.70
10.00
umol/l
0.17
26
280
12
124
0.97
0.00
1.2
1.1
—
—
—
0
0
7
74
0.94
0.00
1.0
1.1
—
—
—
0
0
7
78
0.89
-0.00
3.6
4.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
29.65
—
0
6
0
9
0.00
-0.00
0.0
1.1
—
27.33
—
0
9
0
9
0.00
-0.00
0.0
5.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.0
—
45.17
—
0
6
5
57
0.88
-0.00
1.4
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
0.02
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
64.00
—
0
5
0
6
0.00
-0.00
0.0
1.3
—
38.67
—
0
6
6
64
0.94
-0.00
1.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
7.7
—
25.44
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
18.60
—
0
5
0
8
0.00
-0.00
0.0
1.6
—
63.50
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
1.20
—
0
5
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_INSITU_MELANOMA_UPPERLIMB – Melanoma in situ of upper limb, including shoulder

GWS hits: 1

This endpoint is excluded from FinRegistry analyses (omitted endpoint).