No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
109 |
4. Check minimum number of eventsNone |
109 |
5. Include endpointsNone |
109 |
6. Filter based on genotype QC (FinnGen only) |
95 |
Control definitions (FinnGen only)
- Control exclude
- H7_OCUMUSCLE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H50
- Name in latin
- Strabismus mechanicus
Similar endpoints
↥List of similar endpoints to
Mechanical strabismus
based on the number of shared cases.
Similar with more cases:
- Other strabismus
- Strabismus
- Disorders of ocular muscles, binocular movement, accommodation and refraction
- Diseases of the eye and adnexa
- Any operation in hilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 628 | 362 | 266 |
| Only index persons | 526 | 307 | 219 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | - | 33.99 | 31.00 |
| Only index persons | 44.68 | 45.23 | 43.92 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 95 | 66 | 29 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.01 |
| Median age at first event (years) | 56.85 | 54.89 | 61.29 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 100
- Matched controls
- 1000
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H50.6
ICD-10 Finland
Mechanical strabismus
+∞
144.2
100
*
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
34.9
60.9
44
22
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
758.2
47.4
43
*
H03BB01
ATC
carbimazole; oral
22.9
44.0
37
25
XCW99
NOMESCO Finland
Other investigative procedure of eye
14.7
36.6
41
45
H53.2
ICD-10 Finland
Diplopia
96.2
35.0
37
6
CEC00
NOMESCO Finland
Recession of extraocular muscle
+∞
30.8
28
*
H50.2
ICD-10 Finland
Vertical strabismus
+∞
28.5
26
*
CEW99
NOMESCO Finland
Other operation on extraocular muscle
+∞
26.2
24
*
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
+∞
26.2
24
*
H50.0
ICD-10 Finland
Convergent concomitant strabismus
+∞
25.0
23
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
7.0
20.8
46
108
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
25.4
20.1
28
15
H50.8
ICD-10 Finland
Other specified strabismus
+∞
16.1
15
*
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
188.2
16.0
16
*
H06.2
ICD-10 Finland
Dysthyroid exophthalmos
+∞
15.0
14
*
H03AA01
ATC
levothyroxine sodium; systemic
4.7
13.3
49
169
CE2W4
NOMESCO Finland
Eye movement mapping
+∞
12.8
12
*
104
Kela drug reimbursment
Thyroid insufficiency
6.7
11.7
21
38
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
+∞
11.7
11
*
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
+∞
11.7
11
*
CEC90
NOMESCO Finland
Total transposition of extraocular muscle or muscles
+∞
11.7
11
*
ZXA10
NOMESCO Finland
Bilateral
4.4
10.6
35
109
BAA60
NOMESCO Finland
Total thyroidectomy
14.3
10.3
17
14
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
3.9
9.9
64
314
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
110.0
9.6
10
*
CAC30
NOMESCO Finland
Decompression of orbit to sinuses
+∞
9.5
9
*
WX100
NOMESCO Finland
Conjunctival surface anesthesia
4.7
9.3
26
70
H50.52
ICD-10 Finland
Exophoria
55.0
8.8
10
*
CAC44
NOMESCO Finland
Combined decompression of orbit
98.0
8.6
9
*
T85
ICPC
Hyperthyroidism/thyrotoxicosis
+∞
8.4
8
*
H50.1
ICD-10 Finland
Divergent concomitant strabismus
+∞
8.4
8
*
WX402
NOMESCO Finland
General anaesthesia
3.6
8.4
39
151
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
4.8
8.4
22
56
WF002
NOMESCO Finland
Radical radiotherapy
7.3
8.4
20
33
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
3.3
8.0
48
217
XCK00
NOMESCO Finland
Perimetry
9.3
8.0
16
20
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
16.8
7.9
12
8
H02AB06
ATC
prednisolone; systemic
3.3
7.8
63
339
WX002
NOMESCO Finland
Sedation and analgesia
3.6
7.4
31
111
CAC10
NOMESCO Finland
Reconstruction of orbital wall using bone graft or plate
+∞
7.4
7
*
S02.30
ICD-10 Finland
Fracture of orbital floor, closed
+∞
7.4
7
*
L04AX03
ATC
methotrexate; systemic
4.4
7.1
20
54
ZX120
NOMESCO Finland
Intravenous
4.3
6.6
19
52
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.9
6.4
49
249
CEC30
NOMESCO Finland
Resection of extraocular muscle
+∞
6.3
6
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.8
6.2
50
260
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
38
33
17.96
39.35
9.0
2.4
6.80
4.59
iu/l
0.69
30
17
35
64
7.88
20.04
9.7
3.9
4.50
4.59
pmol/l
0.23
35
57
79
528
3.36
6.06
12.5
9.2
3.61
3.96
e9/l
0.82
66
455
20
71
3.27
4.72
1.6
1.3
208.89
139.62
u/ml
—
9
29
51
317
2.24
3.82
3.6
3.1
—
—
—
0
0
6
7
9.02
3.31
1.0
1.1
—
—
—
0
0
38
234
2.01
2.72
2.0
2.1
2.65
2.79
mg/l
0.15
32
209
94
833
3.14
2.44
16.8
13.8
83.87
83.95
ml/min/173m2
0.01
86
773
65
498
1.87
2.28
4.9
3.6
0.00
0.00
estimate
-0.00
19
119
57
424
1.80
2.16
3.3
2.4
73.06
74.17
nmol/l
0.11
49
381
65
508
1.80
2.04
5.1
3.7
0.00
0.00
estimate
-0.00
18
115
40
272
1.78
2.02
3.6
3.1
0.30
0.22
e6/l
0.20
34
194
15
74
2.21
1.86
2.7
2.1
0.03
0.18
e6/l
2.19
15
69
64
506
1.74
1.85
4.8
3.6
0.00
0.00
estimate
-0.00
19
121
26
159
1.86
1.83
3.3
2.9
3.81
2.38
e6/l
0.19
16
82
7
24
3.06
1.75
1.9
1.3
—
—
—
0
0
15
77
2.12
1.70
3.2
2.1
413.47
385.34
nmol/l
0.22
15
71
81
695
1.87
1.66
8.5
7.7
69.93
78.43
u/l
2.56
76
657
5
14
3.70
1.63
3.4
3.8
6.62
11.60
pmol/l
—
5
14
7
28
2.61
1.48
1.4
1.3
—
—
—
0
0
9
41
2.31
1.41
8.8
8.4
24.94
24.06
mmol/l
—
9
41
56
451
1.55
1.32
8.1
6.3
1.22
1.22
mmol/l
0.06
51
401
19
117
1.77
1.30
2.1
3.2
0.84
0.74
ug/l
0.21
12
76
8
36
2.33
1.27
1.3
1.8
47.13
43.61
u/l
—
8
31
19
286
0.59
1.27
2.0
3.8
12.85
11.02
mg/mmol
0.07
11
175
12
206
0.53
1.27
1.4
1.3
15.82
23.82
iu/ml
—
5
74
37
276
1.54
1.21
4.6
3.5
0.00
0.00
estimate
-0.00
18
111
30
216
1.56
1.14
2.2
2.1
—
—
—
0
0
16
98
1.75
1.11
1.6
1.4
—
—
—
0
0
94
883
2.07
1.02
17.3
14.0
23.73
22.83
mg/l
0.07
74
712
88
811
1.71
0.93
5.7
5.9
36.53
38.66
mmol/mol
3.56
88
773
15
96
1.66
0.90
1.6
1.5
—
—
—
0
0
8
48
1.72
0.81
15.9
8.0
0.84
0.62
%
—
8
48
23
172
1.44
0.72
3.6
2.8
0.43
1.02
e6/l
1.40
14
95
44
368
1.35
0.72
5.7
3.5
0.00
0.00
estimate
-0.00
15
99
9
138
0.62
0.66
3.3
2.4
—
—
—
0
0
21
157
1.43
0.66
4.1
4.9
21.81
21.05
%
—
10
78
8
50
1.65
0.63
16.1
7.9
1.44
1.32
%
—
8
50
8
50
1.65
0.63
1.3
2.2
—
—
—
0
0
8
124
0.61
0.59
3.4
2.1
—
—
—
0
0
49
428
1.28
0.56
2.8
2.6
—
—
estimate
—
0
0
26
209
1.33
0.54
4.9
3.6
1.02
1.02
kg/l
0.03
16
140
33
278
1.28
0.49
6.3
3.1
0.00
0.00
estimate
-0.00
16
98
7
49
1.46
0.47
1.3
1.6
—
—
—
0
0
15
192
0.74
0.43
1.5
1.6
1.63
1.16
mg/l
—
8
150
5
34
1.49
0.41
1.2
1.7
—
—
—
0
0
5
34
1.49
0.41
1.2
1.2
—
—
—
0
0
17
135
1.31
0.38
1.7
1.7
—
—
—
0
0
20
165
1.27
0.34
1.4
1.5
—
—
—
0
0
12
93
1.33
0.31
4.3
7.4
—
—
—
0
0
8
62
1.32
0.29
1.5
2.2
—
—
—
0
0
0
11
0.00
0.21
0.0
2.3
—
13.34
—
0
11
0
11
0.00
0.21
0.0
2.5
—
21.30
—
0
11
0
10
0.00
0.21
0.0
1.6
—
9.60
—
0
5
0
10
0.00
0.21
0.0
2.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
8
70
1.16
0.17
1.4
1.5
—
—
—
0
0
6
79
0.74
0.16
2.0
1.4
—
—
—
0
0
10
83
1.23
0.16
2.3
3.4
—
—
—
0
0
56
585
0.90
0.15
3.5
3.3
—
—
—
0
0
7
85
0.81
0.15
1.1
3.3
5.34
5.58
kpa
—
7
85
33
314
1.08
0.08
2.6
3.8
11.91
26.27
ng/l
3.25
16
217
11
120
0.91
0.05
11.0
5.5
106.09
104.02
mmol/l
1.36
11
120
41
403
1.03
0.01
2.4
2.0
95.54
97.45
pmol/l
0.09
18
210
25
256
0.97
0.00
1.3
1.4
0.42
1.44
u/ml
—
6
76
20
197
1.02
0.00
1.6
1.6
—
—
—
0
0
23
231
0.99
0.00
1.8
3.2
337.63
1091.81
ng/l
3.88
16
202
0
9
0.00
0.00
0.0
1.3
—
113.56
—
0
9
0
9
0.00
0.00
0.0
1.2
—
294.08
—
0
9
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
6.60
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
4.57
—
0
5
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
5.45
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
5
52
0.96
-0.00
6.2
7.0
24.88
24.39
mmol/l
—
5
52
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
9.90
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.9
—
46.71
—
0
7
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.4
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
6
0.00
-0.00
0.0
1.0
—
128.67
—
0
6
0
7
0.00
-0.00
0.0
2.6
—
282.29
—
0
7
0
5
0.00
-0.00
0.0
4.6
—
0.60
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
0
7
0.00
-0.00
0.0
1.0
—
118.57
—
0
7
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_STRABMECH and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have H7_STRABMECH.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: H7_STRABMECH – Mechanical strabismus
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data