Disorder of bilirubin metabolism, other/unspecified

E4_PORBILIRNAS

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — E80.6, E80.7 Hospital discharge: ICD-9 — 2774X Cause of death: ICD-10 — E80.6, E80.7 Cause of death: ICD-9 — 2774X 2 out of 7 registries used, show all original rules.	60
4. Check minimum number of events None	60
5. Include endpoints None	60
6. Filter based on genotype QC (FinnGen only)	57

Control definitions (FinnGen only)

Control exclude: E4_METABOLIA

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2

NAME	E4_PORBILIRNAS
CONTROL_EXCLUDE	E4_METABOLIA
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	E80[6-7]
HD_ICD_9	2774X
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	E80[6-7]
COD_ICD_9	2774X
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Disorder of bilirubin metabolism, other/unspecified based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	486	210	276
Only index persons	423	185	238
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	-	43.10	42.16
Only index persons	42.70	45.65	40.40

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	57	25	32
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	58.50	62.50	55.38

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
58: Matched controls
580

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

E80.7

ICD-10 Finland

Disorder of bilirubin metabolism, unspecified

+∞

39.0

E80.6

ICD-10 Finland

Other disorders of bilirubin metabolism

+∞

26.0

E80.4

ICD-10 Finland

Gilbert syndrome

+∞

8.5

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3034770) Mitochondria Ab [Titer] in Serum

23.34

12.10

1.4

1.2

—

titre

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

15.63

4.70

1.1

1.2

—

(3026285) Alpha 1 antitrypsin [Mass/volume] in Serum or Plasma

15.63

4.70

1.0

1.58

1.42

g/l

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

3.50

4.23

1.3

1.5

—

(3007164) IgA [Mass/volume] in Serum or Plasma

114

3.10

4.12

1.5

1.4

1.73

2.31

g/l

1.15

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

312

3.67

3.93

7.5

3.0

60.89

43.49

u/l

0.80

293

(3032080) INR in Blood by Coagulation assay

211

2.86

3.65

22.9

10.9

1.35

1.21

inr

0.82

171

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

6.43

3.47

1.4

1.3

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

206

2.57

3.05

10.0

5.8

35.69

35.47

g/l

0.07

192

(3027945) Reticulocytes/Erythrocytes in Blood

3.02

2.99

2.9

3.8

1.91

1.81

0.08

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

2.84

2.92

1.4

1.6

—

(3044640) Blood type and Crossmatch panel - Blood

146

2.42

2.66

3.4

3.0

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

3.44

2.50

1.4

1.6

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

230

2.32

2.44

10.2

9.0

1.23

1.22

mmol/l

0.18

195

(3042936) Bacteria identified in Isolate by Culture

2.57

2.35

1.8

1.6

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

3.05

2.20

15.7

14.8

24.28

24.44

mmol/l

—

(3020961) Endomysium IgA Ab [Titer] in Serum

3.54

2.19

1.1

1.2

—

(3035350) Ketones [Presence] in Urine by Test strip

257

2.21

2.16

3.5

4.1

0.00

estimate

—

(42870588) Differential panel, method unspecified - Blood

157

2.19

2.16

6.0

9.9

—

(3003694) ABO and Rh group [Type] in Blood

141

2.20

2.12

1.5

1.4

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

3.27

2.02

10.8

9.9

0.61

0.57

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

3.15

1.94

10.9

9.6

1.22

1.65

—

(36660697) Celiac disease serology panel - Serum

2.85

1.90

1.2

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

218

2.04

1.88

13.6

8.8

1.22

1.21

mmol/l

0.09

200

(3024928) Oxygen saturation in Venous blood

4.10

1.75

6.8

23.3

67.48

69.69

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

206

1.95

1.66

4.2

3.4

—

estimate

—

(3015736) pH of Urine

198

1.93

1.63

3.7

3.8

6.33

6.28

0.09

107

(3014576) Chloride [Moles/volume] in Serum or Plasma

2.21

1.60

13.4

8.4

104.21

104.97

mmol/l

0.23

(3013650) Neutrophils [#/volume] in Blood by Automated count

286

1.95

1.57

9.6

14.3

3.69

3.93

e9/l

0.32

252

(3022145) Colonoscopy Study observation

2.48

1.56

1.2

1.3

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

182

1.90

1.56

2.0

1.9

1.27

1.36

mmol/l

0.28

141

(3018418) pH of Serum or Plasma

139

1.94

1.53

4.8

4.5

7.39

7.40

0.76

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

2.26

1.51

1.3

2.4

1.57

1.68

—

(3013115) Eosinophils [#/volume] in Blood

259

1.89

1.50

5.9

9.0

0.17

0.19

e9/l

0.31

223

(3001604) Monocytes [#/volume] in Blood

250

1.87

1.48

5.8

8.8

0.60

0.56

e9/l

0.43

215

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

2.92

1.47

1.3

1.0

—

(3021601) Nitrite [Presence] in Urine by Test strip

260

1.87

1.47

3.5

4.1

0.00

estimate

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

3.32

1.47

2.4

1.9

—

(3018095) Leukocytes [#/volume] in Urine

177

1.85

1.43

3.2

4.2

9.01

42.79

e6/l

1.62

132

(3006315) Basophils [#/volume] in Blood

252

1.84

1.42

5.8

8.8

0.04

e9/l

0.21

214

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

3.12

1.39

2.4

1.9

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

3.12

1.39

2.0

1.8

—

(3023368) Bacteria identified in Blood by Culture

127

1.88

1.35

4.7

—

(3009261) Glucose [Presence] in Urine by Test strip

265

1.81

1.34

3.5

4.1

0.00

estimate

—

(40768804) Tissue Pathology biopsy report

172

1.80

1.31

2.2

2.0

—

(4035726) Immunohistochemistry procedure

2.41

1.30

1.8

1.5

—

(3020682) Albumin/Creatinine [Ratio] in Urine

129

1.84

1.28

3.6

3.7

5.79

12.78

mg/mmol

0.56

(3002256) Pathology report gross observation

2.15

1.27

1.6

1.2

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

113

1.86

1.25

3.7

3.3

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

2.78

1.24

1.0

1.3

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

2.78

1.24

2.0

1.8

—

(3002032) Base excess in Venous blood by calculation

2.16

1.19

14.8

8.5

2.19

0.91

mmol/l

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

2.64

1.17

1.6

1.3

—

(3002582) Erythrocytes [#/volume] in Urine

159

1.74

1.16

2.4

3.4

19.27

416.81

e6/l

0.52

129

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.91

1.14

1.7

2.0

—

(3001334) Neutrophil cytoplasmic Ab [Units/volume] in Serum

2.51

1.11

1.2

—

(3012516) Albumin [Mass/volume] in Urine

126

1.76

1.09

2.9

41.01

56.08

mg/l

0.24

(40764999) Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)/1.73 sq M

427

1.95

1.09

20.9

15.4

84.51

81.75

ml/min/173m2

0.36

396

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

2.07

1.09

7.4

3.3

—

(3012544) pH of Venous blood

2.07

1.09

14.8

9.3

7.40

7.39

—

(36304419) Bacteria [Presence] in Urine

135

1.73

1.08

2.5

3.3

—

estimate

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.99

1.07

1.8

—

(3019198) Lymphocytes [#/volume] in Blood

259

1.64

1.00

6.0

8.7

1.81

1.74

e9/l

0.18

227

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

174

1.65

0.99

4.8

3.4

31.42

33.95

ng/l

0.05

123

(3007853) Bacteria identified in Skin by Aerobe culture

1.91

0.90

1.1

1.6

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.11

0.90

1.5

1.9

—

(3030467) Casts [#/volume] in Urine by Automated count

142

1.62

0.88

2.6

3.2

0.10

0.33

e6/l

0.99

111

(40760892) CBC W Ordered Manual Differential panel - Blood

125

1.64

0.86

6.9

6.8

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

1.78

0.86

2.8

3.6

2.98

1.83

e6/l

—

(3000991) Gas panel - Venous blood

1.81

0.85

20.5

11.9

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

471

2.00

0.82

23.6

15.3

25.51

23.36

mg/l

0.20

373

(3020891) Body temperature

2.09

0.74

11.8

3.0

36.86

°c

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

1.66

0.74

3.0

3.3

2.38

1.23

e6/l

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.80

0.73

1.1

1.5

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

1.76

0.71

14.7

9.7

24.47

23.41

mmol/l

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.74

0.70

2.0

1.8

—

(40761511) CBC panel - Blood by Automated count

480

1.80

0.70

25.3

13.9

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

197

1.47

0.67

2.6

1.9

74.84

93.83

pmol/l

1.20

(3026008) Bacteria identified in Urine by Culture

137

1.46

0.56

3.4

2.7

—

(3021589) Normoblasts [#/volume] in Blood

232

1.40

0.55

15.7

16.0

0.00

0.06

e9/l

0.60

195

(3022313) Gas panel - Capillary blood

1.56

0.53

9.5

6.1

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

112

1.46

0.51

3.9

4.7

—

(3013512) EKG study

158

1.41

0.51

3.8

3.6

—

(40768797) Stomach Pathology biopsy report

1.50

0.45

1.0

1.2

—

(3028626) Oxygen [Partial pressure] in Capillary blood

1.67

0.44

9.8

7.7

9.10

8.95

kpa

—

(3019225) pH of Specimen

1.61

0.43

5.6

5.8

7.39

7.35

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.56

0.42

1.6

1.3

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

0.00

0.42

0.0

1.1

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.42

0.0

1.5

—

1.54

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.42

0.0

1.5

—

0.89

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

211

1.32

0.41

3.7

3.8

0.00

estimate

—

(3014007) Fractional oxyhemoglobin in Arterial blood

1.47

0.40

16.4

11.7

97.04

93.37

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

311

1.32

0.40

2.7

3.1

—

(1761868) Lipid panel - Serum or Plasma

194

1.31

0.38

2.8

3.1

—

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

1.37

0.35

4.5

4.7

1.27

1.22

mmol/l

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.42

0.33

1.7

1.4

—

(3029937) Albumin [Presence] in Urine by Test strip

150

1.29

0.31

3.3

4.4

0.00

estimate

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.28

0.31

1.4

2.0

—

(3041096) Erythrocytes [Presence] in Urine by Automated

152

1.27

0.28

3.3

3.1

0.00

estimate

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

1.38

0.24

16.4

11.1

1.10

1.72

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

143

0.80

0.22

4.9

4.3

22.10

19.83

—

(1616796) Gas panel - Central venous blood

0.00

0.21

0.0

4.2

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

0.00

0.21

0.0

1.4

—

(3045142) Bone marrow Pathology biopsy report

0.00

0.21

0.0

1.5

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

0.00

0.21

0.0

1.1

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.0

—

(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.3

—

(3044941) Cell count panel - Synovial fluid

0.00

0.21

0.0

1.2

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

0.21

0.0

1.2

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.27

0.21

1.5

2.0

—

(3019150) Specific gravity of Urine by Refractometry

109

1.25

0.21

3.5

4.5

1.02

kg/l

—

(40761536) Microorganisms panel - Urine sediment

1.25

0.21

3.0

4.4

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.20

0.0

1.6

—

(3000475) Leukocytes [#/volume] in Synovial fluid

0.00

0.20

0.0

1.1

—

15497.11

—

(3000494) Fungus identified in Specimen by Culture

1.21

0.19

1.1

1.5

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.21

0.19

1.7

2.2

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

0.82

0.15

1.5

1.6

—

(40758558) Short blood count panel - Blood

143

1.16

0.13

6.6

6.4

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

424

1.16

0.12

5.1

5.0

2.48

1.96

mu/l

1.48

387

(3000850) Epithelial cells [#/volume] in Urine

117

1.14

0.09

1.8

2.5

6.95

3.67

e6/l

0.47

102

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.82

0.09

1.4

—

(3002385) Erythrocyte [DistWidth] in Red Blood Cells

407

1.12

0.08

31.0

20.1

14.00

13.63

0.47

401

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.0

1.7

—

(3040151) Glucose [Moles/volume] in Capillary blood

0.00

0.0

1.3

—

5.10

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

0.0

20.7

—

712.00

—

(21494434) Karyotype in Bone marrow

0.00

0.0

1.0

—

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

0.0

12.0

—

7.50

—

(3036428) Adenosine deaminase [Enzymatic activity/volume] in Pleural fluid

0.00

0.0

1.0

—

9.17

—

(3001684) Respiratory syncytial virus Ag [Presence] in Specimen

0.00

0.0

1.3

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.5

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

-0.00

0.0

2.3

—

(3009595) Pneumocystis jirovecii DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.1

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

-0.00

0.0

1.2

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

4.4

—

58.40

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

-0.00

0.0

1.0

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

-0.00

0.0

1.4

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3013201) Beta-2-Microglobulin [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

4.88

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

-0.00

0.0

1.2

—

(3017732) Neutrophils [#/volume] in Blood

0.90

-0.00

2.2

3.2

3.57

4.12

e9/l

—

(40760848) Basement membrane zone BP180 Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.6

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3052649) Adenosine deaminase [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

13.00

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

-0.00

0.0

1.3

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

-0.00

0.0

1.4

—

(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(3045788) Cell count panel - Pleural fluid

0.00

-0.00

0.0

2.2

—

(3009466) Valproate [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

4.6

—

340.38

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3025130) Human papilloma virus identified in Specimen

0.00

-0.00

0.0

2.1

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

-0.00

0.0

2.1

—

(3027901) Hemoglobin [Mass/volume] in Arterial cord blood

0.00

-0.00

0.0

1.0

—

170.86

—

(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.4

—

(3005791) Eosinophil cationic protein (ECP) [Mass/volume] in Serum

0.00

-0.00

0.0

1.2

—

17.42

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

-0.00

0.0

1.4

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

-0.00

0.0

1.1

—

(3047826) Mullerian inhibiting substance [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

2.34

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

0.85

-0.00

11.8

6.1

—

(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

-0.00

0.0

2.0

—

(3021788) Differential panel - Synovial fluid

0.00

-0.00

0.0

1.5

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

-0.00

0.0

1.2

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

-0.00

0.0

1.4

—

Mortality – FinRegistry

↥

Association

Association between endpoint E4_PORBILIRNAS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have E4_PORBILIRNAS.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: E4_PORBILIRNAS – Disorder of bilirubin metabolism, other/unspecified

GWS hits: 2

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Disorder of bilirubin metabolism, other/unspecified

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints