No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditions
|
556897 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
302 |
4. Check minimum number of eventsNone |
302 |
5. Include endpointsNone |
302 |
6. Filter based on genotype QC (FinnGen only) |
273 |
Control definitions (FinnGen only)
- Control conditions
- not Q17_CLEFT_PALATE_EXCLUDE
Extra metadata
- First used in FinnGen datafreeze
- DF10
Similar endpoints
↥List of similar endpoints to
Cleft lip and cleft lip and palate
based on the number of shared cases.
Similar with more cases:
- Cleft lip, lip and palate or palate
- Congenital malformations, deformations and chromosomal abnormalities
- Congenital malformations, deformations and chromosomal abnormalities, including avohilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3787 | 1514 | 2265 |
| Only index persons | 3203 | 1302 | 1901 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.04 | 0.06 |
| Only index persons | 0.06 | 0.05 | 0.07 |
| Median age at first event (years) | |||
| Whole population | 0.78 | 1.04 | 0.51 |
| Only index persons | 1.26 | 2.28 | 0.56 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 273 | 144 | 129 |
| Unadjusted period prevalence (%) | 0.05 | 0.05 | 0.06 |
| Median age at first event (years) | 7.56 | 11.60 | 3.06 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 283
- Matched controls
- 2829
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q37.1
ICD-10 Finland
Cleft hard palate with unilateral cleft lip
+∞
169.3
145
*
74920
ICD-8 Finland
Cleft palate and cleft lip, Cheilognathopalatoschisis unilateralis
+∞
106.1
95
*
4361
FHL
Lip plastic or reconstruction due to cleft lip
+∞
73.1
67
*
7492A
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate with cleft lip[CHEILOPALATOSCHISIS UNILATERALIS COMPLETA]
+∞
73.1
67
*
EAB30
NOMESCO Finland
Correction of cleft lip
+∞
66.3
61
*
Q37.0
ICD-10 Finland
Cleft hard palate with bilateral cleft lip
+∞
64.0
59
*
SBB10
NOMESCO Finland
Dental impressions
8.8
63.5
101
167
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
14.1
60.7
61
54
SJX10
NOMESCO Finland
Orthodontic treatment/control appointment, short
13.2
58.9
62
59
SAA04
NOMESCO Finland
Special examination of mouth
9.3
49.3
68
93
Q35.1
ICD-10 Finland
Cleft hard palate
556.9
48.9
47
*
Q36.9
ICD-10 Finland
Cleft lip, unilateral
+∞
47.2
44
*
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
10.7
46.5
56
64
ECB17
NOMESCO Finland
Operation of gingival cleft
+∞
46.1
43
*
74924
ICD-8 Finland
Cleft palate and cleft lip, Cheilognathopalatoschisis bilateralis
+∞
42.8
40
*
EB1MA
NOMESCO Finland
Cephalometry with X-ray
11.4
42.4
48
50
4367
FHL
Bone transfer to the upper jaw
+∞
41.7
39
*
SJD20
NOMESCO Finland
Placement of modified orthodontic arch wire
13.5
40.3
40
34
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
15.0
39.8
37
28
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
6.8
38.2
70
130
7492C
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate with cleft lip[CHEILOPALATOSCHISIS BILATERALIS COMPLETA]
+∞
37.3
35
*
4368
FHL
Closing the fistula of the mouth
+∞
37.3
35
*
SJD00
NOMESCO Finland
Removal and/or reactivation of orthodontic arch wire
10.1
36.8
45
52
4122
FHL
Tympanostomy (tympanic tube)
14.1
36.4
35
28
4365
FHL
Correction of nasal deformity
+∞
36.2
34
*
EEC05
NOMESCO Finland
Le Fort I osteotomy
185.9
32.4
33
*
ZSZ10
NOMESCO Finland
Secondary repair operation
185.9
32.4
33
*
SJC50
NOMESCO Finland
Removal of fixed orthodontic appliance with at least 7 brackets
10.2
31.0
37
41
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
37.4
30.9
39
12
EBB10
NOMESCO Finland
Insertion of dental implant
37.4
30.9
39
12
4364
FHL
Pharyngeal tongue plastic
+∞
30.8
29
*
74910
ICD-8 Finland
Cleft palate and cleft lip, Cheiloschisis unilateralis
+∞
30.8
29
*
DLW00
NOMESCO Finland
Correction of cleft nose
+∞
27.5
26
*
4362
FHL
Nozzle reconstruction
+∞
26.5
25
*
K00.00
ICD-10 Finland
Hypodontia
28.3
26.0
35
14
SJD40
NOMESCO Finland
Placement of prefabricated palatal or lingual arch
7.8
25.7
38
55
ZXD10
NOMESCO Finland
Scheduled procedure
3.5
23.9
143
640
74929
ICD-8 Finland
Cleft palate and cleft lip, Unspecified
+∞
23.2
22
*
SJD10
NOMESCO Finland
Placement of orthodontic arch wire
8.0
23.0
33
46
SJB00
NOMESCO Finland
Fitting of removable appliance incl. patient instructions
7.8
22.5
33
47
Q35.9
ICD-10 Finland
Cleft palate, unspecified
+∞
22.2
21
*
74912
ICD-8 Finland
Cleft palate and cleft lip, Cheilognathoschisis unilateralis
+∞
22.2
21
*
Q37.99
ICD-10 Finland
Cleft palate with cleft lip NOS
+∞
22.2
21
*
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
8.2
22.1
31
42
74900
ICD-8 Finland
Cleft palate and cleft lip, Cleft palate
+∞
21.1
20
*
4366
FHL
Upper jaw scar repair surgery
+∞
21.1
20
*
DLD20
NOMESCO Finland
Rhinoplasty
62.3
20.2
23
*
EHC10
NOMESCO Finland
Plastic repair of oronasal or oroantral fistula of palate
+∞
20.0
19
*
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
7.3
20.0
31
47
SJB60
NOMESCO Finland
Adjustment and grinding of removable appliance
8.6
19.5
26
33
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
59.3
19.2
22
*
EBB15
NOMESCO Finland
Insertion of dental implant abutment
41.5
18.9
23
6
H65.3
ICD-10 Finland
Chronic mucoid otitis media
6.4
18.3
32
55
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
39.5
17.9
22
6
Z2221
NOMESCO Finland
Medical doctor
3.0
17.8
114
513
ZZG00
NOMESCO Finland
Graft of cartilage
+∞
16.8
16
*
K07.14
ICD-10 Finland
Retrognaty, maxillary
95.8
16.8
18
*
SJD30
NOMESCO Finland
Demanding placement of orthodontic arch wire
14.1
16.0
27
21
UDC00
NOMESCO Finland
Ear microscopy
4.7
15.9
40
96
Q37.90
ICD-10 Finland
Unspecified cheft palate with cleft lip, unilateral
+∞
15.8
15
*
7490A
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate[PALATOSCHISIS COMPLETA]
+∞
15.8
15
*
9808
FHL
Bone graft
168.9
15.6
16
*
WZC00
NOMESCO Finland
Treatment plan or consultation
2.7
14.9
140
756
4204
FHL
Molding of the cartilaginous part of the nose
157.8
14.6
15
*
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
15.5
14.3
23
16
SPC20
NOMESCO Finland
Implant borne crown
44.9
14.3
17
*
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
5.1
13.9
31
67
7491B
ICD-9 Finland
Cleft palate and cleft lip, Cleft lip[CHEILOSCHISIS UNILATERALIS INCOMPLETA]
+∞
13.6
13
*
ZSZ00
NOMESCO Finland
Primary repair operation
+∞
13.6
13
*
SJA04
NOMESCO Finland
Very demanding workplan for orthodontic treatment
146.7
13.6
14
*
SPA20
NOMESCO Finland
Selection and insertion of implant abutment
146.7
13.6
14
*
SJC10
NOMESCO Finland
Orthodontic band in one tooth
5.7
13.5
26
49
SXC05
NOMESCO Finland
Other oral or dental procedure
3.6
13.2
49
156
ZXB10
NOMESCO Finland
Medial
30.0
13.1
17
6
ZXE10
NOMESCO Finland
More than one and less than three hours
2.6
12.8
117
612
DLD10
NOMESCO Finland
Reconstruction of cartilage and bone of nose
+∞
12.6
12
*
4347
FHL
Osteotomy of the upper jaw
135.7
12.5
13
*
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
39.4
12.3
15
*
SAA03
NOMESCO Finland
Extended examination of mouth
2.4
12.0
157
960
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
10.7
11.7
22
22
Q37.3
ICD-10 Finland
Cleft soft palate with unilateral cleft lip
+∞
11.5
11
*
K08.2
ICD-10 Finland
Atrophy of edentulous alveolar ridge
36.7
11.4
14
*
SJC00
NOMESCO Finland
Bondable bracket or other fixed attachement
62.4
10.7
12
*
SPF20
NOMESCO Finland
Temporary relining of dentures
114.0
10.5
11
*
7491F
ICD-9 Finland
Cleft palate and cleft lip, Cleft lip[CHEILOGNATOSCHISIS UNILATERALIS INCOMPLETA]
+∞
10.5
10
*
7490B
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate[PALATOSCHISIS INCOMPLETA]
+∞
10.5
10
*
7491A
ICD-9 Finland
Cleft palate and cleft lip, Cleft lip[CHEILOSCHISIS UNILATERALIS COMPLETA]
+∞
10.5
10
*
EHC40
NOMESCO Finland
Repair of submucous cleft palate
+∞
10.5
10
*
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
5.2
10.4
22
45
1450
FHL
Otomicroscopy
33.9
10.4
13
*
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
4.4
9.9
26
64
SPF10
NOMESCO Finland
Demanding reparation of dental prosthesis
27.1
9.9
13
5
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
3.8
9.8
31
88
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
5.6
9.8
19
36
SPC40
NOMESCO Finland
Preparation of first or second intermediate attachment tooth for bridge
57.0
9.7
11
*
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
8.5
9.5
20
25
WX408
NOMESCO Finland
General anesthesy, balanced
2.4
9.5
88
454
4203
FHL
Mobilization and repositioning of the external pyramid
103.3
9.5
10
*
Q36.0
ICD-10 Finland
Cleft lip, bilateral
+∞
9.4
9
*
SPA10
NOMESCO Finland
Setting attachments on tooth or implanted bracket or imblant based structures
+∞
9.4
9
*
Q35.71
ICD-10 Finland
Submucous cleft palate
+∞
9.4
9
*
ZXE20
NOMESCO Finland
More than three and less than five hours
2.9
9.3
47
179
ZXE00
NOMESCO Finland
One hour or less
2.2
9.0
122
732
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
10.0
8.9
17
18
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.1
8.9
143
917
EBA10
NOMESCO Finland
Operative extraction of tooth
2.5
8.7
67
316
DLD00
NOMESCO Finland
Reconstruction of cartilage of nose
51.6
8.7
10
*
SPB10
NOMESCO Finland
Manufacture of a temporary crown to tooth at the dental office
16.9
8.6
13
8
38401
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) chronica adhaesiva
13.3
8.5
14
11
ECB60
NOMESCO Finland
Reconstruction of alveolus
+∞
8.4
8
*
Q37.8
ICD-10 Finland
Unspecified cleft palate with bilateral cleft lip
+∞
8.4
8
*
SXC03
NOMESCO Finland
Other oral or dental procedure
15.1
8.3
13
9
SJC40
NOMESCO Finland
Removal of fixed orthodontic appliance with at most 6 brackets
4.3
8.2
22
55
3812A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic mucoid otitis media
7.6
8.1
18
25
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
22.8
8.1
11
5
J01DA08
ATC
[U] cefaclor
2.5
7.8
54
242
ZZH22
NOMESCO Finland
Graft of patients own bone, block
46.3
7.8
9
*
SPE90
NOMESCO Finland
Other partial denture
19.0
7.7
11
6
J34.2
ICD-10 Finland
Deviated nasal septum
3.4
7.6
29
93
SPB20
NOMESCO Finland
Temporary bridge
25.8
7.6
10
*
4121
FHL
Tympanic puncture or parasentosis in general anesthesia or operating room
9.7
7.4
14
15
ENC80
NOMESCO Finland
Plastic operation of soft palate for voice distubance
+∞
7.3
7
*
74913
ICD-8 Finland
Cleft palate and cleft lip, Cheilognathoschisis bilateralis
+∞
7.3
7
*
SPF30
NOMESCO Finland
Relining of denture
16.3
7.3
11
7
H66.0
ICD-10 Finland
Acute suppurative otitis media
2.5
7.1
50
225
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
6.4
6.9
17
28
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.5
6.8
47
210
EB1WA, ,
NOMESCO Finland
12.6
6.6
11
9
SJD50
NOMESCO Finland
Placement of prefabricated palatal or lingual arch, dentist-made
12.6
6.6
11
9
R1260
NOMESCO Finland
Evaluation of communicative skills
10.4
6.6
12
12
SJX20
NOMESCO Finland
Orthodontic treatment/control appointment
5.6
6.6
18
34
SJA01
NOMESCO Finland
Assesment of orthodontic treatment need
71.4
6.5
7
*
EAB20
NOMESCO Finland
Plastic repair of lip
71.4
6.5
7
*
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
3.8
6.3
19
52
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
3.8
6.3
19
52
Q67.48
ICD-10 Finland
Other specified congenital deformity of skull, face or jaw
+∞
6.3
6
*
H74.1
ICD-10 Finland
Adhesive middle ear disease
+∞
6.3
6
*
Q37.2
ICD-10 Finland
Cleft soft palate with bilateral cleft lip
+∞
6.3
6
*
SJA03
NOMESCO Finland
Demanding workplan for orthodontic treatment
27.3
6.3
8
*
EB1AD
NOMESCO Finland
Cone beam CT of teeth and jaws (one quarter)
27.3
6.3
8
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.6
6.1
20
58
SJB10
NOMESCO Finland
Fitting of removable appliance incl. patient instructions, demanding
7.0
6.1
14
21
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
10
31
3.30
2.54
1.2
1.4
—
—
—
0
0
0
46
0.00
1.72
0.0
1.5
—
—
—
0
0
0
44
0.00
1.52
0.0
1.5
—
—
—
0
0
5
16
3.16
1.44
1.4
1.3
91.20
76.94
umol/l
—
5
16
230
2432
0.71
1.40
12.6
12.4
26.83
21.41
mg/l
1.03
188
1913
0
37
0.00
1.35
0.0
5.6
—
672.58
—
0
37
0
39
0.00
1.35
0.0
1.8
—
—
—
0
0
50
378
1.39
1.26
2.7
2.7
1.39
0.73
e6/l
0.78
27
184
10
49
2.08
1.23
5.8
6.0
—
3468.13
—
0
8
31
429
0.69
1.16
1.3
1.3
1.29
7.40
u/ml
2.85
14
160
17
104
1.67
1.12
14.4
16.5
16.29
16.53
%
0.10
17
98
20
128
1.60
1.11
17.3
12.7
0.73
0.70
%
0.12
20
128
20
130
1.58
1.06
17.4
12.7
95.69
94.34
%
1.34
20
130
20
131
1.57
1.03
17.4
12.6
1.38
1.33
%
0.08
20
131
0
32
0.00
0.95
0.0
1.9
—
—
—
0
0
48
380
1.32
0.92
4.5
3.2
104.06
304.36
ng/l
0.93
33
248
37
282
1.36
0.91
12.2
7.9
104.51
104.60
mmol/l
0.04
37
282
29
212
1.41
0.90
13.0
12.1
13.44
12.84
kpa
0.25
29
203
29
212
1.41
0.90
13.0
12.2
5.10
5.17
kpa
0.20
29
202
53
427
1.30
0.90
1.3
1.5
—
—
—
0
0
8
139
0.56
0.85
4.3
1.8
—
—
—
0
0
0
24
0.00
0.79
0.0
1.7
—
—
—
0
0
0
24
0.00
0.79
0.0
1.7
—
—
—
0
0
0
24
0.00
0.79
0.0
1.7
—
—
—
0
0
65
547
1.24
0.78
2.5
2.3
—
—
—
0
0
38
476
0.77
0.78
1.3
1.3
27.48
25.38
iu/ml
0.06
11
145
0
27
0.00
0.78
0.0
1.7
—
—
—
0
0
0
28
0.00
0.76
0.0
1.7
—
—
—
0
0
0
28
0.00
0.76
0.0
1.7
—
—
—
0
0
0
28
0.00
0.76
0.0
1.7
—
—
—
0
0
0
28
0.00
0.76
0.0
1.7
—
—
—
0
0
0
28
0.00
0.76
0.0
1.7
—
—
—
0
0
26
194
1.37
0.74
19.7
10.4
1.07
1.25
mmol/l
0.63
26
189
23
168
1.40
0.74
1.0
1.1
—
—
—
0
0
62
726
0.81
0.72
2.5
3.0
20.99
25.24
ng/l
0.18
35
418
7
40
1.77
0.71
1.7
1.5
—
—
—
0
0
43
350
1.27
0.69
2.8
2.8
1.75
3.05
e6/l
0.73
21
157
164
1752
0.85
0.67
8.4
7.6
79.92
81.35
u/l
0.19
159
1667
24
180
1.36
0.67
14.2
12.1
117.71
126.20
g/l
1.06
24
174
10
62
1.63
0.66
4.0
5.8
—
689.67
—
0
6
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
0
20
0.00
0.60
0.0
1.6
—
2.67
—
0
20
0
21
0.00
0.60
0.0
1.2
—
—
—
0
0
164
1740
0.86
0.57
4.2
4.1
9.65
8.90
mm/h
0.40
159
1647
266
2705
0.72
0.57
19.2
19.1
4.65
4.62
e12/l
0.55
258
2651
15
107
1.42
0.56
11.2
4.8
0.56
0.61
%
0.24
15
107
15
108
1.41
0.54
11.2
4.7
1.41
1.31
%
0.10
15
108
10
146
0.67
0.53
1.3
1.1
0.88
0.92
g/l
—
10
146
266
2703
0.73
0.53
19.2
19.2
259.03
255.98
e9/l
0.34
258
2654
10
145
0.68
0.52
1.3
1.1
1.49
1.53
g/l
—
10
145
9
65
1.40
0.51
5.2
1.8
0.58
0.89
nmol/l
—
9
56
22
173
1.29
0.48
18.2
11.8
25.50
25.25
mmol/l
0.12
22
173
7
48
1.47
0.47
1.0
1.3
—
—
—
0
0
63
560
1.16
0.44
1.7
2.4
2.52
2.61
mg/l
0.11
56
492
11
151
0.72
0.44
1.7
1.3
—
—
—
0
0
8
58
1.39
0.42
1.3
1.1
—
—
—
0
0
5
33
1.52
0.41
2.6
3.5
98.80
22.74
u/ml
—
5
33
0
15
0.00
0.41
0.0
1.7
—
3.88
—
0
8
0
15
0.00
0.41
0.0
3.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
1.14
—
0
9
0
15
0.00
0.41
0.0
1.1
—
113.43
—
0
7
11
149
0.73
0.41
1.1
1.7
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
3.4
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
3.4
—
—
—
0
0
0
18
0.00
0.40
0.0
1.8
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
9.06
—
0
18
96
888
1.12
0.38
4.2
3.3
31.66
30.45
u/l
0.13
90
846
8
115
0.69
0.37
2.3
1.6
—
—
—
0
0
67
608
1.13
0.36
3.4
2.9
0.16
0.28
e6/l
0.75
50
429
5
79
0.63
0.36
1.0
1.3
—
7.27
—
0
17
13
167
0.77
0.35
1.2
1.3
—
29.48
—
0
10
136
1426
0.91
0.31
8.1
10.7
3.90
3.90
e9/l
0.00
112
1225
7
53
1.33
0.31
2.3
1.3
—
—
—
0
0
218
2232
0.90
0.29
12.3
11.1
90.50
91.62
ml/min/173m2
0.33
199
2028
225
2196
1.12
0.29
4.4
4.1
5.80
5.75
mmol/l
0.18
216
2067
66
715
0.90
0.29
2.4
2.6
0.00
0.01
estimate
0.50
20
195
253
2568
0.86
0.29
10.8
10.5
28.78
28.73
u/l
0.01
247
2525
79
734
1.11
0.29
2.3
3.0
2.38
2.36
mmol/l
0.75
71
683
13
103
1.27
0.28
1.9
1.7
—
—
—
0
0
29
253
1.16
0.27
4.4
2.3
42.22
29.19
u/l
2.05
23
209
8
65
1.24
0.27
1.4
1.6
42.58
51.50
ug/l
—
8
65
73
678
1.10
0.27
1.9
1.7
—
—
—
0
0
10
77
1.31
0.26
2.8
4.1
25.55
24.60
mmol/l
—
10
77
5
75
0.66
0.26
1.4
1.7
—
—
—
0
0
5
75
0.66
0.26
1.0
1.3
—
—
—
0
0
17
142
1.21
0.25
1.5
1.4
358.44
248.70
miu/ml
0.48
11
71
211
2158
0.91
0.25
5.6
5.1
37.97
37.94
mmol/mol
0.02
204
2068
180
1853
0.92
0.25
3.6
3.4
44.61
41.60
u/l
0.22
175
1789
11
87
1.27
0.24
1.4
1.6
—
—
—
0
0
28
247
1.15
0.23
1.5
1.5
736.94
1197.14
nmol/l
2.79
23
197
57
527
1.10
0.23
1.9
2.2
0.89
1.12
mg/l
0.44
48
403
5
42
1.19
0.21
3.6
1.7
13.70
13.21
%
—
5
42
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
0.33
—
0
11
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
60.12
—
0
11
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
2.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
2.2
—
—
—
0
0
0
12
0.00
0.21
0.0
2.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
4.5
—
181.46
—
0
13
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
90
855
1.08
0.20
2.1
1.9
90.24
97.34
pmol/l
0.87
45
435
9
111
0.80
0.20
1.4
2.0
248.56
232.37
pmol/l
—
9
106
31
279
1.12
0.20
2.2
2.3
—
—
—
0
0
0
14
0.00
0.20
0.0
2.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
96.00
—
0
6
0
14
0.00
0.20
0.0
2.1
—
—
—
0
0
0
14
0.00
0.20
0.0
2.1
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
14
0.00
0.20
0.0
1.0
—
119.71
—
0
14
0
14
0.00
0.20
0.0
10.5
—
34.83
—
0
6
0
14
0.00
0.20
0.0
2.1
—
—
—
0
0
6
52
1.16
0.19
1.0
1.2
—
1.43
—
0
9
32
290
1.12
0.19
1.6
1.8
3.80
3.56
mmol/l
0.39
19
212
52
556
0.92
0.18
4.8
3.3
1.02
1.02
kg/l
0.61
29
349
5
68
0.73
0.17
1.2
1.3
—
1.00
—
0
6
5
68
0.73
0.17
1.4
2.2
—
—
—
0
0
46
429
1.09
0.16
3.6
3.8
17.40
21.54
%
0.84
14
165
190
1862
1.06
0.15
4.5
4.2
14.31
14.56
pmol/l
0.81
182
1751
9
82
1.10
0.15
1.2
1.8
—
—
—
0
0
7
90
0.77
0.14
1.6
1.1
—
5.27
—
0
15
10
118
0.84
0.14
1.8
1.3
—
—
—
0
0
24
218
1.11
0.14
1.2
1.3
184.20
162.82
u/ml
0.07
11
88
8
97
0.82
0.14
1.6
1.3
—
—
—
0
0
235
2377
0.93
0.14
15.3
13.5
3.95
3.94
mmol/l
0.12
230
2334
25
228
1.11
0.13
1.8
1.8
—
—
—
0
0
128
1313
0.95
0.12
7.1
5.4
6.67
6.36
mmol/l
0.60
120
1225
15
133
1.13
0.12
2.5
2.7
65.04
67.20
g/l
0.70
15
128
16
178
0.89
0.11
1.4
1.5
—
—
—
0
0
127
1242
1.04
0.10
3.9
3.2
0.00
0.00
estimate
-0.00
21
241
234
2361
0.95
0.09
4.3
4.4
1.42
1.44
mmol/l
0.45
225
2250
5
48
1.04
0.09
1.4
2.2
0.00
0.00
g/l
—
5
48
5
62
0.80
0.08
1.4
1.3
—
—
—
0
0
92
943
0.96
0.08
3.5
3.1
0.00
0.01
estimate
0.74
19
203
222
2198
1.04
0.08
5.4
4.9
1.95
1.81
mu/l
0.99
216
2090
128
1257
1.03
0.07
3.9
3.3
0.00
0.00
estimate
-0.00
22
239
36
377
0.95
0.07
2.1
2.0
3.82
3.61
ratio
0.35
25
296
12
109
1.10
0.06
3.2
11.6
25.25
24.42
mmol/l
0.57
12
103
25
239
1.05
0.04
1.8
1.7
—
—
—
0
0
63
642
0.98
0.03
3.6
3.4
0.09
0.00
estimate
0.45
22
233
48
491
0.97
0.03
2.1
2.2
—
—
—
0
0
22
212
1.04
0.02
3.9
4.8
234.59
242.37
u/l
0.14
22
204
236
2368
0.98
0.02
4.3
4.5
4.78
4.75
mmol/l
0.19
228
2269
101
1019
0.99
0.02
2.0
1.9
1.42
1.42
mmol/l
0.01
91
898
224
2231
1.02
0.01
18.1
16.0
333.26
334.10
g/l
0.74
224
2224
198
1971
1.01
0.01
3.7
3.6
—
—
—
0
0
20
207
0.96
0.01
4.2
5.9
—
—
—
0
0
32
313
1.02
0.01
1.7
1.9
—
—
—
0
0
106
1052
1.01
0.01
2.8
2.8
—
—
estimate
—
0
0
222
2226
0.99
0.01
3.5
3.8
1.34
1.29
mmol/l
0.53
213
2107
10
106
0.94
0.01
1.6
1.4
—
—
—
0
0
23
236
0.97
0.00
2.1
2.2
—
—
—
0
0
239
2383
1.02
0.00
5.0
4.9
2.91
2.85
mmol/l
0.51
232
2271
102
1026
0.99
0.00
10.4
8.1
1.21
1.21
mmol/l
0.07
97
911
55
544
1.01
0.00
2.3
2.3
—
—
—
0
0
34
336
1.01
0.00
3.1
2.5
0.60
0.70
ug/l
0.55
19
173
71
710
1.00
0.00
1.3
1.5
1.04
1.61
u/ml
0.81
21
179
16
156
1.03
0.00
1.4
1.6
0.30
0.30
mg/l
—
8
70
17
171
0.99
0.00
2.1
2.8
—
—
—
0
0
47
469
1.00
0.00
5.2
3.3
1110.80
776.53
ng/l
0.20
40
382
59
586
1.01
0.00
3.8
4.0
5.55
9.82
mg/mmol
0.79
42
383
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
0.08
—
0
5
0
5
0.00
0.00
0.0
3.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
12.30
—
0
5
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
11.44
—
0
8
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
5
52
0.96
-0.00
2.6
4.0
3.74
3.93
mmol/l
—
5
52
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
1.13
—
0
6
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
127
1266
1.01
-0.00
3.9
3.3
0.00
0.01
estimate
0.50
20
225
8
85
0.94
-0.00
1.3
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
6.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
127.00
—
0
9
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
5
53
0.94
-0.00
1.4
2.1
0.00
0.00
g/l
—
5
48
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
8.20
—
0
8
0
8
0.00
-0.00
0.0
2.0
—
4.64
—
0
8
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
5
52
0.96
-0.00
1.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint Q17_CLEFT_LIP_OR_LIP_AND_PALATE and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have Q17_CLEFT_LIP_OR_LIP_AND_PALATE.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: Q17_CLEFT_LIP_OR_LIP_AND_PALATE – Cleft lip and cleft lip and palate
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data