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Cleft lip and palate

Q17_CLEFT_LIP_AND_PALATE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

  • not Q17_CLEFT_PALATE_EXCLUDE
556897

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Q37
  • Hospital discharge: ICD-9 7492[ABCDE]
  • Hospital discharge: ICD-8 74920|74924
  • Cause of death: ICD-10 Q37
  • Cause of death: ICD-9 7492[ABCDE]
  • Cause of death: ICD-8 74920|74924

2 out of 7 registries used, show all original rules.

235

4. Check minimum number of events

None

235

5. Include endpoints

None

235

6. Filter based on genotype QC (FinnGen only)

210

Control definitions (FinnGen only)

Control conditions
not Q17_CLEFT_PALATE_EXCLUDE

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 210 112 98
Unadjusted period prevalence (%) 0.04 0.04 0.04
Median age at first event (years) 10.62 14.74 5.91

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
218
Matched controls
2179
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q37.1
ICD-10 Finland
Cleft hard palate with unilateral cleft lip
+∞
177.1
145
*
74920
ICD-8 Finland
Cleft palate and cleft lip, Cheilognathopalatoschisis unilateralis
+∞
108.7
95
*
7492A
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate with cleft lip[CHEILOPALATOSCHISIS UNILATERALIS COMPLETA]
+∞
74.3
67
*
SBB10
NOMESCO Finland
Dental impressions
12.0
68.8
90
121
Q37.0
ICD-10 Finland
Cleft hard palate with bilateral cleft lip
+∞
64.9
59
*
4361
FHL
Lip plastic or reconstruction due to cleft lip
+∞
59.1
54
*
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
15.3
56.3
55
47
SAA04
NOMESCO Finland
Special examination of mouth
12.3
54.0
62
68
SJX10
NOMESCO Finland
Orthodontic treatment/control appointment, short
14.5
52.0
52
46
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
13.5
51.2
54
52
EAB30
NOMESCO Finland
Correction of cleft lip
+∞
51.1
47
*
Q35.1
ICD-10 Finland
Cleft hard palate
542.7
46.0
44
*
ECB17
NOMESCO Finland
Operation of gingival cleft
+∞
45.4
42
*
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
8.8
44.3
68
107
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
18.4
43.6
37
24
74924
ICD-8 Finland
Cleft palate and cleft lip, Cheilognathopalatoschisis bilateralis
+∞
43.2
40
*
EB1MA
NOMESCO Finland
Cephalometry with X-ray
14.2
42.4
42
36
SJD00
NOMESCO Finland
Removal and/or reactivation of orthodontic arch wire
13.8
39.8
40
35
4367
FHL
Bone transfer to the upper jaw
+∞
39.8
37
*
SJD20
NOMESCO Finland
Placement of modified orthodontic arch wire
15.8
38.3
35
26
4368
FHL
Closing the fistula of the mouth
+∞
37.6
35
*
7492C
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate with cleft lip[CHEILOPALATOSCHISIS BILATERALIS COMPLETA]
+∞
37.6
35
*
4365
FHL
Correction of nasal deformity
+∞
33.2
31
*
EEC05
NOMESCO Finland
Le Fort I osteotomy
193.2
32.7
33
*
EBB10
NOMESCO Finland
Insertion of dental implant
47.0
32.5
39
10
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
42.8
31.8
39
11
K00.00
ICD-10 Finland
Hypodontia
57.1
29.4
34
7
4364
FHL
Pharyngeal tongue plastic
+∞
28.8
27
*
ZSZ10
NOMESCO Finland
Secondary repair operation
+∞
28.8
27
*
SJC50
NOMESCO Finland
Removal of fixed orthodontic appliance with at least 7 brackets
11.9
28.7
31
30
4362
FHL
Nozzle reconstruction
+∞
26.6
25
*
SJD40
NOMESCO Finland
Placement of prefabricated palatal or lingual arch
9.5
25.9
33
40
DLW00
NOMESCO Finland
Correction of cleft nose
+∞
25.5
24
*
SJD10
NOMESCO Finland
Placement of orthodontic arch wire
10.4
25.3
30
33
Q35.9
ICD-10 Finland
Cleft palate, unspecified
+∞
22.3
21
*
Q37.99
ICD-10 Finland
Cleft palate with cleft lip NOS
+∞
22.3
21
*
74929
ICD-8 Finland
Cleft palate and cleft lip, Unspecified
+∞
22.3
21
*
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
9.3
21.9
28
34
H65.3
ICD-10 Finland
Chronic mucoid otitis media
9.3
21.9
28
34
4122
FHL
Tympanostomy (tympanic tube)
20.6
21.6
32
18
ZXD10
NOMESCO Finland
Scheduled procedure
3.8
21.6
116
498
DLD20
NOMESCO Finland
Rhinoplasty
85.4
21.1
23
*
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
121.7
21.0
22
*
EBB15
NOMESCO Finland
Insertion of dental implant abutment
63.8
20.3
23
*
EHC10
NOMESCO Finland
Plastic repair of oronasal or oroantral fistula of palate
+∞
20.1
19
*
WZC00
NOMESCO Finland
Treatment plan or consultation
3.7
19.9
123
570
74900
ICD-8 Finland
Cleft palate and cleft lip, Cleft palate
+∞
18.0
17
*
K07.14
ICD-10 Finland
Retrognaty, maxillary
195.1
17.8
18
*
SJB00
NOMESCO Finland
Fitting of removable appliance incl. patient instructions
7.9
17.3
25
35
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
54.7
17.3
20
*
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
7.2
17.1
27
42
ZZG00
NOMESCO Finland
Graft of cartilage
+∞
16.9
16
*
Q36.9
ICD-10 Finland
Cleft lip, unilateral
+∞
16.9
16
*
4366
FHL
Upper jaw scar repair surgery
+∞
16.9
16
*
UDC00
NOMESCO Finland
Ear microscopy
5.5
16.8
36
76
ZXE10
NOMESCO Finland
More than one and less than three hours
3.2
16.0
103
475
SJD30
NOMESCO Finland
Demanding placement of orthodontic arch wire
21.2
15.9
23
12
Q37.90
ICD-10 Finland
Unspecified cheft palate with cleft lip, unilateral
+∞
15.8
15
*
Z2221
NOMESCO Finland
Medical doctor
3.2
15.4
91
397
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
18.2
15.1
23
14
ZXB10
NOMESCO Finland
Medial
61.1
15.0
17
*
7490A
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate[PALATOSCHISIS COMPLETA]
+∞
14.7
14
*
74912
ICD-8 Finland
Cleft palate and cleft lip, Cheilognathoschisis unilateralis
+∞
14.7
14
*
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
11.7
14.7
27
26
SAA03
NOMESCO Finland
Extended examination of mouth
3.1
14.7
132
725
9808
FHL
Bone graft
160.2
14.6
15
*
SXC05
NOMESCO Finland
Other oral or dental procedure
4.3
14.4
42
114
SJC10
NOMESCO Finland
Orthodontic band in one tooth
7.0
14.4
23
36
SPC20
NOMESCO Finland
Implant borne crown
45.9
14.3
17
*
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
80.3
13.8
15
*
SPA20
NOMESCO Finland
Selection and insertion of implant abutment
148.8
13.6
14
*
SJA04
NOMESCO Finland
Very demanding workplan for orthodontic treatment
148.8
13.6
14
*
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
4.9
13.1
31
71
ZXE20
NOMESCO Finland
More than three and less than five hours
3.8
13.0
45
138
DLD10
NOMESCO Finland
Reconstruction of cartilage and bone of nose
+∞
12.6
12
*
4204
FHL
Molding of the cartilaginous part of the nose
137.5
12.6
13
*
4347
FHL
Osteotomy of the upper jaw
137.5
12.6
13
*
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
13.5
12.4
21
17
Q37.3
ICD-10 Finland
Cleft soft palate with unilateral cleft lip
+∞
11.6
11
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.9
11.5
76
344
K08.2
ICD-10 Finland
Atrophy of edentulous alveolar ridge
37.2
11.4
14
*
1450
FHL
Otomicroscopy
45.8
11.0
13
*
J34.2
ICD-10 Finland
Deviated nasal septum
4.6
11.0
28
68
SPF20
NOMESCO Finland
Temporary relining of dentures
115.3
10.5
11
*
EHC40
NOMESCO Finland
Repair of submucous cleft palate
+∞
10.5
10
*
SPF10
NOMESCO Finland
Demanding reparation of dental prosthesis
34.4
10.4
13
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.5
10.1
118
697
SJB60
NOMESCO Finland
Adjustment and grinding of removable appliance
9.4
10.0
20
23
SJC00
NOMESCO Finland
Bondable bracket or other fixed attachement
57.6
9.7
11
*
SPC40
NOMESCO Finland
Preparation of first or second intermediate attachment tooth for bridge
57.6
9.7
11
*
EBA10
NOMESCO Finland
Operative extraction of tooth
2.9
9.6
55
228
4203
FHL
Mobilization and repositioning of the external pyramid
104.3
9.5
10
*
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
11.4
9.5
17
16
3812A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic mucoid otitis media
11.4
9.5
17
16
SXC03
NOMESCO Finland
Other oral or dental procedure
22.9
9.5
13
6
7491F
ICD-9 Finland
Cleft palate and cleft lip, Cleft lip[CHEILOGNATOSCHISIS UNILATERALIS INCOMPLETA]
+∞
9.4
9
*
SPA10
NOMESCO Finland
Setting attachments on tooth or implanted bracket or imblant based structures
+∞
9.4
9
*
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
4.8
9.3
22
50
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
38.4
9.1
11
*
SPB10
NOMESCO Finland
Manufacture of a temporary crown to tooth at the dental office
19.6
9.0
13
7
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
9.6
8.7
17
19
Z01.1
ICD-10 Finland
Examination of ears and hearing
3.0
8.5
42
160
DLD00
NOMESCO Finland
Reconstruction of cartilage of nose
93.5
8.5
9
*
ECB60
NOMESCO Finland
Reconstruction of alveolus
+∞
8.4
8
*
Q37.8
ICD-10 Finland
Unspecified cleft palate with bilateral cleft lip
+∞
8.4
8
*
7490B
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate[PALATOSCHISIS INCOMPLETA]
+∞
8.4
8
*
SPF30
NOMESCO Finland
Relining of denture
23.0
8.1
11
5
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
8.3
8.0
17
22
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.8
7.8
18
40
ZZH22
NOMESCO Finland
Graft of patients own bone, block
46.7
7.8
9
*
SPE90
NOMESCO Finland
Other partial denture
19.2
7.7
11
6
SPB20
NOMESCO Finland
Temporary bridge
26.0
7.6
10
*
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
4.4
7.4
19
46
SJC40
NOMESCO Finland
Removal of fixed orthodontic appliance with at most 6 brackets
4.6
7.4
18
42
ZSZ00
NOMESCO Finland
Primary repair operation
+∞
7.3
7
*
Q35.71
ICD-10 Finland
Submucous cleft palate
+∞
7.3
7
*
ENC80
NOMESCO Finland
Plastic operation of soft palate for voice distubance
+∞
7.3
7
*
SJD50
NOMESCO Finland
Placement of prefabricated palatal or lingual arch, dentist-made
16.4
7.3
11
7
ZXE00
NOMESCO Finland
One hour or less
2.2
7.3
95
568
SJA03
NOMESCO Finland
Demanding workplan for orthodontic treatment
41.4
6.8
8
*
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
6.8
6.8
16
25
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
3.3
6.8
27
90
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
2.7
6.7
41
174
SXB00
NOMESCO Finland
Removal of sutures from oral mucosa
3.5
6.5
23
71
EB1WA, ,
NOMESCO Finland
14.9
6.5
10
7
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
5.9
6.4
17
31
J01DA08
ATC
[U] cefaclor
2.6
6.4
41
178
R1260
NOMESCO Finland
Evaluation of communicative skills
11.5
6.4
11
10
74913
ICD-8 Finland
Cleft palate and cleft lip, Cheilognathoschisis bilateralis
+∞
6.3
6
*
SJA01
NOMESCO Finland
Assesment of orthodontic treatment need
+∞
6.3
6
*
Q37.2
ICD-10 Finland
Cleft soft palate with bilateral cleft lip
+∞
6.3
6
*
Q67.48
ICD-10 Finland
Other specified congenital deformity of skull, face or jaw
+∞
6.3
6
*
EB1AD
NOMESCO Finland
Cone beam CT of teeth and jaws (one quarter)
27.5
6.3
8
*
M95.0
ICD-10 Finland
Acquired deformity of nose
27.5
6.3
8
*
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
13.0
6.1
10
8
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
13.0
6.1
10
8
38401
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) chronica adhaesiva
10.5
6.1
11
11

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
34
203
1.80
2.35
2.1
1.6
—
—
—
0
0
43
588
0.66
1.60
1.5
1.5
—
—
—
0
0
70
567
1.34
1.20
2.4
2.2
—
—
—
0
0
178
1879
0.71
1.09
12.7
12.6
27.16
22.02
mg/l
0.72
146
1486
7
35
2.03
1.01
1.3
1.2
—
—
—
0
0
7
35
2.03
1.01
1.0
1.1
—
—
—
0
0
29
214
1.41
0.88
13.0
7.8
104.21
104.65
mmol/l
0.22
29
214
22
305
0.69
0.87
1.2
1.3
—
—
—
0
0
22
304
0.69
0.86
3.2
2.5
100.53
84.36
ug/g
0.18
17
240
28
369
0.72
0.84
1.3
1.3
37.14
24.35
iu/ml
—
7
112
24
174
1.43
0.81
10.2
4.7
7.37
7.38
ph
0.30
18
97
0
25
0.00
0.79
0.0
2.6
—
39.87
—
0
25
0
27
0.00
0.78
0.0
1.3
—
—
—
0
0
0
27
0.00
0.78
0.0
1.3
—
—
—
0
0
0
27
0.00
0.78
0.0
1.3
—
—
—
0
0
0
27
0.00
0.78
0.0
1.3
—
—
—
0
0
25
331
0.72
0.77
1.3
1.3
1.28
7.48
u/ml
2.40
12
124
49
589
0.78
0.77
2.9
3.2
23.54
23.94
ng/l
0.01
29
355
23
169
1.40
0.73
8.7
13.1
7.44
7.42
ph
—
9
94
23
169
1.40
0.73
8.8
13.0
13.45
12.72
kpa
0.26
23
162
23
169
1.40
0.73
8.8
13.1
5.18
5.18
kpa
0.01
23
161
5
26
1.94
0.71
4.2
2.3
8.56
6.83
mmol/l
—
5
26
12
77
1.59
0.70
6.1
18.9
16.68
16.39
%
0.08
12
72
68
586
1.23
0.70
2.3
3.1
2.38
2.37
mmol/l
0.50
60
543
43
519
0.79
0.70
2.3
2.1
—
—
—
0
0
5
27
1.87
0.69
2.6
3.9
98.80
17.13
u/ml
—
5
27
63
540
1.23
0.68
3.0
2.9
18.37
45.84
e6/l
0.98
49
399
15
103
1.49
0.67
11.7
13.2
0.74
0.71
%
0.11
15
103
5
28
1.80
0.66
1.0
1.3
—
—
—
0
0
8
127
0.62
0.66
1.4
1.7
—
—
—
0
0
50
419
1.25
0.66
1.6
2.1
2.74
2.74
mg/l
0.00
45
362
15
104
1.47
0.64
11.7
13.3
95.91
94.05
%
1.74
15
104
6
105
0.56
0.63
1.7
1.8
—
—
—
0
0
23
298
0.74
0.63
1.4
1.9
—
—
—
0
0
10
63
1.61
0.63
2.8
3.8
25.55
24.54
mmol/l
—
10
63
76
670
1.21
0.62
2.1
1.8
89.57
98.30
pmol/l
1.08
41
349
47
554
0.81
0.62
2.7
2.6
0.00
0.01
estimate
0.50
17
152
8
51
1.59
0.61
5.6
1.6
0.62
0.98
nmol/l
—
8
43
0
20
0.00
0.60
0.0
1.3
—
17.40
—
0
20
0
21
0.00
0.60
0.0
1.5
—
0.17
—
0
15
59
677
0.82
0.60
15.4
9.7
1.21
1.13
inr
0.54
47
548
0
22
0.00
0.59
0.0
2.6
—
—
—
0
0
27
212
1.31
0.59
1.2
1.6
—
—
—
0
0
43
360
1.24
0.57
2.4
2.5
8.34
4.76
e6/l
0.60
38
331
15
107
1.43
0.57
11.7
12.9
1.37
1.39
%
0.02
15
107
22
169
1.33
0.55
9.0
13.0
1.52
0.77
mmol/l
0.38
22
139
16
117
1.40
0.54
12.8
10.2
25.62
25.21
mmol/l
0.17
16
117
6
100
0.59
0.53
4.8
4.7
—
—
—
0
0
20
153
1.34
0.52
9.3
14.0
96.34
96.23
%
0.02
20
148
72
642
1.18
0.51
3.9
3.6
21.73
40.78
e6/l
0.80
49
422
16
211
0.74
0.50
1.5
1.8
—
—
—
0
0
7
108
0.64
0.50
1.4
1.1
1.49
1.55
g/l
—
7
108
7
109
0.63
0.50
1.4
1.1
0.88
0.89
g/l
—
7
109
95
1032
0.86
0.50
6.3
7.0
0.18
0.19
e9/l
0.18
84
898
20
156
1.31
0.47
18.6
11.0
—
—
—
0
0
28
229
1.25
0.46
2.3
2.2
—
—
—
0
0
7
50
1.41
0.45
1.0
1.3
—
—
—
0
0
18
139
1.32
0.45
9.9
13.2
116.50
125.68
g/l
1.00
18
134
62
690
0.86
0.44
1.9
1.9
—
—
—
0
0
27
222
1.25
0.43
1.3
1.5
—
—
—
0
0
17
216
0.77
0.42
1.2
1.2
—
—
—
0
0
163
1692
0.85
0.42
5.7
5.2
38.18
37.99
mmol/mol
0.09
157
1614
73
801
0.87
0.42
2.1
1.9
1.37
1.39
mmol/l
0.06
64
693
8
57
1.42
0.42
1.3
1.3
—
—
—
0
0
5
32
1.57
0.42
4.2
2.3
1.32
1.36
mmol/l
—
5
32
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
0.13
—
0
6
0
17
0.00
0.41
0.0
3.4
—
—
—
0
0
0
17
0.00
0.41
0.0
2.2
—
17.12
—
0
17
53
470
1.17
0.40
5.3
4.8
—
—
—
0
0
0
18
0.00
0.40
0.0
1.7
—
—
—
0
0
67
736
0.87
0.39
3.8
3.1
0.00
0.02
estimate
0.74
16
159
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
5.6
—
10.56
—
0
19
57
633
0.86
0.39
5.8
6.3
—
—
—
0
0
9
67
1.36
0.38
1.9
1.3
—
91.11
—
0
9
5
36
1.40
0.38
1.6
18.7
1.14
1.27
mmol/l
—
5
30
24
198
1.24
0.38
1.3
1.4
—
—
—
0
0
24
200
1.22
0.35
1.5
1.5
726.03
1222.05
nmol/l
2.66
19
154
6
44
1.37
0.34
1.0
1.5
—
—
—
0
0
12
155
0.76
0.34
1.3
1.5
—
—
—
0
0
24
201
1.22
0.34
3.9
2.3
43.00
29.51
u/l
1.75
19
166
6
45
1.34
0.34
1.3
1.7
—
—
—
0
0
150
1441
1.13
0.33
4.7
4.2
14.30
14.60
pmol/l
0.89
143
1349
191
1949
0.83
0.33
10.6
10.7
—
—
—
0
0
50
553
0.88
0.32
4.4
6.2
—
—
—
0
0
7
56
1.26
0.29
1.7
1.3
—
—
—
0
0
13
103
1.28
0.29
1.2
1.3
—
—
—
0
0
94
994
0.90
0.28
6.4
6.6
0.04
0.04
e9/l
0.01
83
843
9
120
0.74
0.28
4.2
3.3
—
—
—
0
0
94
993
0.91
0.27
6.3
6.6
0.55
0.55
e9/l
0.03
83
845
44
485
0.88
0.27
1.3
1.5
2.23
2.20
g/l
0.05
27
288
74
791
0.90
0.27
4.1
3.1
6.19
6.18
ph
0.03
36
443
9
76
1.19
0.25
1.7
3.2
19.67
21.21
s
—
9
71
13
158
0.81
0.24
1.3
1.4
—
—
—
0
0
20
232
0.85
0.24
1.6
1.2
—
—
—
0
0
13
157
0.82
0.23
1.3
1.4
—
—
—
0
0
12
146
0.81
0.23
1.3
1.5
—
—
—
0
0
94
986
0.92
0.23
4.2
3.3
0.00
0.02
estimate
0.50
17
176
11
135
0.80
0.22
1.5
1.4
—
—
—
0
0
37
407
0.89
0.22
2.0
1.7
—
—
—
0
0
13
156
0.82
0.22
1.3
1.4
—
—
—
0
0
39
427
0.89
0.22
5.1
3.4
1.02
1.02
kg/l
0.54
23
268
175
1711
1.11
0.22
18.7
15.8
333.09
334.04
g/l
0.72
175
1704
5
42
1.19
0.21
1.0
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
155.30
—
0
10
0
12
0.00
0.21
0.0
1.2
—
0.00
—
0
12
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
33
298
1.13
0.21
2.9
3.2
11.14
271.84
ng/l
1.84
22
198
0
13
0.00
0.21
0.0
3.6
—
37.69
—
0
13
0
13
0.00
0.21
0.0
7.2
—
8.08
—
0
13
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
60
561
1.10
0.20
3.3
3.2
8.32
8.85
mmol/l
0.34
52
492
0
14
0.00
0.20
0.0
1.4
—
8.71
—
0
14
97
1012
0.92
0.20
6.2
6.6
1.80
1.95
e9/l
1.06
86
887
6
49
1.23
0.20
1.0
1.2
—
—
—
0
0
6
49
1.23
0.20
1.0
1.2
—
—
—
0
0
180
1831
0.90
0.19
4.2
4.5
1.41
1.45
mmol/l
0.73
172
1735
50
465
1.10
0.19
3.1
2.7
0.16
0.34
e6/l
0.96
38
328
94
980
0.93
0.19
4.1
3.3
0.00
0.00
estimate
-0.00
18
184
44
407
1.10
0.19
1.7
2.0
0.80
1.22
mg/l
0.89
37
316
6
53
1.14
0.19
3.5
13.9
0.85
0.86
%
—
6
47
19
216
0.87
0.18
1.1
1.2
—
—
—
0
0
10
121
0.82
0.18
1.0
1.3
—
31.64
—
0
9
93
969
0.93
0.18
4.1
3.2
0.00
0.00
estimate
-0.00
17
188
19
167
1.15
0.17
1.0
1.3
80.67
175.96
u/ml
—
9
72
12
141
0.84
0.17
1.1
1.1
—
—
—
0
0
197
1992
0.88
0.16
11.3
10.5
28.80
28.56
u/l
0.05
191
1960
8
71
1.13
0.16
2.1
4.2
37.06
36.94
°c
—
8
71
10
83
1.21
0.15
13.9
3.5
1.11
1.35
%
—
10
83
10
83
1.21
0.15
13.9
3.5
0.66
0.63
%
—
10
83
52
550
0.93
0.15
3.8
2.6
—
0.40
—
0
5
139
1422
0.94
0.15
3.4
3.3
43.72
41.44
u/l
0.14
134
1372
49
461
1.08
0.15
3.3
3.4
386.41
53.45
mg/l
0.47
35
309
175
1721
1.08
0.14
4.5
4.2
5.77
5.76
mmol/l
0.03
169
1613
106
1092
0.94
0.14
8.7
10.3
3.79
3.92
e9/l
0.23
88
944
50
472
1.08
0.14
3.7
3.8
5.64
9.30
mg/mmol
0.59
36
302
8
96
0.83
0.14
1.4
1.2
—
—
—
0
0
207
2085
0.85
0.13
19.9
19.3
6.57
6.57
e9/l
0.02
201
2036
88
910
0.94
0.13
6.2
6.5
8.67
8.62
%
0.06
80
867
173
1704
1.07
0.12
5.6
5.0
1.92
1.80
mu/l
0.69
168
1611
37
347
1.08
0.12
1.7
1.6
—
—
—
0
0
207
2084
0.86
0.12
19.9
19.2
4.66
4.61
e12/l
0.86
201
2036
28
260
1.09
0.11
3.0
2.6
1.63
2.54
e6/l
0.36
14
107
88
906
0.95
0.11
6.1
6.5
2.71
2.90
%
0.33
82
860
207
2083
0.87
0.10
19.9
19.3
259.65
254.95
e9/l
0.51
201
2040
51
532
0.95
0.10
1.2
1.4
1.10
1.54
u/ml
0.41
15
132
15
135
1.12
0.10
1.8
2.9
—
—
—
0
0
15
135
1.12
0.10
1.7
1.8
6.36
6.12
ph
—
7
78
31
292
1.07
0.09
2.0
1.6
—
—
—
0
0
82
842
0.96
0.08
2.6
2.8
—
—
—
0
0
17
185
0.91
0.08
1.8
1.6
—
—
—
0
0
6
57
1.05
0.08
9.8
9.6
—
—
—
0
0
6
57
1.05
0.08
1.5
1.5
—
—
—
0
0
11
123
0.89
0.08
1.4
1.5
—
—
—
0
0
182
1836
0.94
0.08
4.3
4.6
4.79
4.74
mmol/l
0.25
175
1752
6
71
0.84
0.08
1.7
1.3
—
—
—
0
0
6
72
0.83
0.08
1.2
1.2
—
—
—
0
0
6
73
0.82
0.07
1.3
1.7
—
—
—
0
0
47
452
1.05
0.07
2.7
2.4
—
—
—
0
0
86
879
0.96
0.07
8.9
9.7
0.00
0.00
e9/l
0.39
61
693
9
87
1.04
0.07
1.4
2.3
—
—
—
0
0
92
938
0.97
0.06
6.0
6.4
28.77
29.38
%
0.20
87
903
11
121
0.90
0.06
1.0
1.1
—
—
—
0
0
89
907
0.97
0.06
6.0
6.5
0.72
0.69
%
0.22
83
853
26
273
0.95
0.05
3.3
2.5
0.59
0.71
ug/l
0.55
15
138
10
90
1.12
0.05
3.3
12.0
25.58
24.36
mmol/l
—
10
85
14
151
0.92
0.05
1.8
1.8
—
0.00
estimate
—
0
36
16
149
1.08
0.05
3.4
4.4
0.80
1.00
%
—
5
49
40
412
0.96
0.04
3.8
4.0
—
—
—
0
0
171
1721
0.97
0.04
3.5
3.9
1.34
1.30
mmol/l
0.39
163
1621
94
928
1.02
0.03
5.7
6.2
55.86
55.91
%
0.01
88
894
10
108
0.92
0.03
1.7
2.4
66.31
67.98
g/l
—
10
103
12
112
1.08
0.03
1.4
1.5
0.32
0.27
mg/l
—
7
45
29
281
1.04
0.02
1.4
1.5
674.29
604.36
titre
—
7
55
84
830
1.02
0.02
2.7
2.7
—
—
estimate
—
0
0
48
471
1.02
0.02
6.6
3.6
7.39
7.40
ph
0.24
33
332
102
1026
0.99
0.00
6.0
5.4
6.47
6.34
mmol/l
0.22
94
954
10
104
0.96
0.00
1.0
1.1
—
—
—
0
0
185
1848
1.00
0.00
5.0
5.0
2.92
2.84
mmol/l
0.64
179
1752
51
511
1.00
0.00
3.6
3.4
0.11
0.01
estimate
0.45
18
180
16
164
0.97
0.00
2.4
2.5
10.90
10.24
g/l
0.36
16
154
22
218
1.01
0.00
1.6
1.9
3.77
3.61
mmol/l
0.25
15
167
7
75
0.93
0.00
1.3
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
76.80
—
0
5
0
8
0.00
-0.00
0.0
1.0
—
-4.71
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
0.67
—
0
8
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
20.55
—
0
6
0
7
0.00
-0.00
0.0
37.1
—
128.57
—
0
7
0
5
0.00
-0.00
0.0
2.8
—
3.94
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
5.82
—
0
5
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
480.75
—
0
8
7
69
1.01
-0.00
1.4
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.9
—
125.33
—
0
9
0
7
0.00
-0.00
0.0
1.9
—
136.84
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
53
0.94
-0.00
2.6
4.5
0.94
1.33
mmol/l
—
5
53
0
5
0.00
-0.00
0.0
4.6
—
0.62
—
0
5
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
160.37
—
0
8
0
7
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
0.04
—
0
6
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
5
55
0.91
-0.00
2.2
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
3.34
—
0
8
0
9
0.00
-0.00
0.0
6.0
—
1.25
—
0
9
7
79
0.88
-0.00
1.6
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
6
62
0.97
-0.00
3.5
12.4
1.15
1.41
%
—
6
56
0
8
0.00
-0.00
0.0
1.6
—
49.50
—
0
8
8
82
0.97
-0.00
2.0
9.8
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: Q17_CLEFT_LIP_AND_PALATE – Cleft lip and palate

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).