≡ Risteys
R14

Documentation Changelog GitHub Contact & Feedback

Onycholysis

DOID Endpoint Browser PheWeb

L12_NAIL_LYSIS

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — L60.1
  • Hospital discharge: ICD-9 — 7038D
  • Hospital discharge: ICD-8 — 70306
  • Cause of death: ICD-10 — L60.1
  • Cause of death: ICD-9 — 7038D
  • Cause of death: ICD-8 — 70306

2 out of 7 registries used, show all original rules.

280

4. Check minimum number of events

None

280

5. Include endpoints

None

280

6. Filter based on genotype QC (FinnGen only)

256

Control definitions (FinnGen only)

Control exclude
L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L60
Name in latin
Onycholysis

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1667 990 666
Only index persons 1526 920 606
Unadjusted period prevalence (%)
Whole population 0.02 0.03 0.02
Only index persons 0.03 0.03 0.02
Median age at first event (years)
Whole population 44.88 48.31 39.98
Only index persons 46.36 49.26 41.97

-FinnGen-

Key figures

All Female Male
Number of individuals 256 176 80
Unadjusted period prevalence (%) 0.05 0.06 0.04
Median age at first event (years) 54.57 52.20 59.79

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
263
Matched controls
2630
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L60.1
ICD-10 Finland
Onycholysis
16384.0
307.7
261
8
L60.0
ICD-10 Finland
Ingrowing nail
7.1
21.6
35
56
L60.9
ICD-10 Finland
Nail disorder, unspecified
15.7
16.7
27
19
QDH01
NOMESCO Finland
Excision of nail bed in toe
114.4
10.5
11
*
S22
ICPC
Nail symptom/complaint
3.7
10.1
34
101
B35.1
ICD-10 Finland
Tinea unguium
3.8
10.1
33
96
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
9.6
139
871
D01BA02
ATC
terbinafine; oral
2.4
9.4
80
399
L03.0
ICD-10 Finland
Cellulitis of finger and toe
3.1
8.5
37
130
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.2
8.4
106
620
QDH00
NOMESCO Finland
Avulsion of toe nail
34.5
8.1
10
*
D01AE16
ATC
amorolfine; topical
2.9
8.1
40
151
L60.8
ICD-10 Finland
Other nail disorders
12.5
7.2
12
10
D07AD01
ATC
clobetasol; topical
2.4
7.0
53
248
WZC00
NOMESCO Finland
Treatment plan or consultation
2.0
6.9
110
693
L60.3
ICD-10 Finland
Nail dystrophy
71.5
6.5
7
*
D07XC01
ATC
betamethasone; topical
2.6
6.3
39
165
SAA03
NOMESCO Finland
Extended examination of mouth
1.9
6.3
117
770
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.1
6.2
68
370

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
80
276
3.73
19.77
2.0
1.5
—
—
—
0
0
58
240
2.82
10.01
2.0
1.7
—
—
—
0
0
120
749
2.11
7.96
8.2
6.5
—
—
—
0
0
157
1115
2.01
6.99
8.5
6.5
9.23
8.58
%
1.60
145
1040
156
1108
2.00
6.92
8.5
6.5
0.75
0.70
%
0.57
143
1026
166
1206
2.02
6.89
8.5
6.3
0.59
0.55
e9/l
1.17
144
1025
156
1109
2.00
6.89
8.5
6.4
2.99
2.78
%
0.61
144
1033
166
1211
2.01
6.75
8.5
6.3
0.04
0.04
e9/l
0.42
144
1024
158
1135
1.98
6.69
8.5
6.5
29.32
28.96
%
0.13
147
1073
166
1225
1.96
6.36
8.6
6.4
1.92
2.03
e9/l
0.37
150
1074
63
335
2.16
6.11
1.4
1.4
360.00
533.85
titre
—
10
78
168
1257
1.93
6.04
8.7
6.6
0.19
0.18
e9/l
0.31
150
1091
177
1358
1.93
5.78
11.3
10.1
3.96
3.93
e9/l
0.04
153
1181
151
1108
1.85
5.59
8.7
6.5
55.49
56.56
%
0.44
142
1055
54
286
2.12
5.24
11.7
5.7
1.06
1.08
mmol/l
0.13
48
263
212
1766
2.03
4.98
11.3
8.0
83.43
76.99
u/l
1.04
201
1675
32
140
2.46
4.84
4.8
3.6
4.65
4.43
pmol/l
0.52
24
131
73
448
1.87
4.63
1.4
1.3
10.85
10.41
u/ml
0.02
20
181
133
979
1.73
4.53
7.4
4.6
35.96
36.27
g/l
0.27
127
929
87
571
1.78
4.41
4.7
4.0
—
—
—
0
0
150
1149
1.71
4.35
11.8
7.1
1.22
1.22
mmol/l
0.00
136
991
19
68
2.93
4.22
2.7
1.7
492.05
233.05
ug/l
0.41
19
61
17
57
3.12
4.20
2.5
2.7
3.71
1.52
index
—
7
31
218
1870
1.97
4.19
6.0
4.4
14.61
14.72
pmol/l
0.26
194
1730
31
145
2.29
4.06
8.4
3.5
7.41
7.42
ph
0.25
22
117
47
261
1.98
3.98
3.0
3.4
5.38
6.77
umol/l
0.49
42
227
136
1033
1.66
3.93
10.4
6.7
1.22
1.22
mmol/l
0.28
130
956
36
184
2.11
3.81
7.7
4.1
7.38
7.34
ph
0.79
27
122
158
1260
1.64
3.66
7.0
6.6
9.94
10.69
umol/l
0.58
145
1194
14
46
3.16
3.58
1.5
1.4
27.02
27.10
u/l
—
9
39
85
585
1.67
3.53
2.7
2.3
2.47
2.84
mg/l
1.52
72
505
240
2164
2.25
3.52
7.3
5.5
1.89
1.86
mu/l
0.15
218
2022
26
121
2.27
3.45
2.8
2.6
269.78
108.52
ng/l
0.90
26
105
130
1000
1.59
3.41
2.1
2.0
101.16
99.29
pmol/l
0.16
60
496
185
1552
1.65
3.35
6.3
4.3
—
1.61
—
0
5
56
348
1.77
3.34
3.8
2.8
18.80
2.86
e6/l
0.42
31
166
92
654
1.63
3.33
1.8
1.6
22.61
20.56
nmol/l
0.55
75
549
95
685
1.61
3.23
3.0
2.8
—
—
—
0
0
135
1058
1.57
3.21
3.8
2.6
79.19
76.94
nmol/l
0.40
123
956
31
160
2.06
3.21
17.8
8.3
11.34
8.57
mmol/l
1.15
31
152
98
714
1.59
3.19
6.6
3.7
7.40
7.39
ph
0.67
78
505
101
744
1.58
3.12
4.3
2.5
57.34
57.18
u/l
0.01
91
687
12
36
3.44
3.06
1.8
3.5
3.50
4.81
e9/l
1.17
12
36
51
317
1.76
3.03
1.3
1.2
—
—
—
0
0
22
103
2.24
2.90
9.4
3.7
—
—
—
0
0
20
90
2.32
2.88
1.5
1.2
—
—
—
0
0
15
59
2.64
2.84
1.1
1.3
—
101.25
—
0
8
56
365
1.68
2.80
6.8
3.5
0.83
0.82
mmol/l
0.16
50
350
9
23
4.01
2.80
1.1
1.3
—
—
—
0
0
87
637
1.55
2.70
4.7
2.8
0.25
0.38
e6/l
0.64
62
453
49
320
1.65
2.43
3.8
2.1
—
—
—
0
0
36
216
1.77
2.41
1.4
1.2
—
—
—
0
0
45
288
1.68
2.40
1.6
1.5
—
—
—
0
0
10
33
3.11
2.38
1.5
1.2
—
—
—
0
0
5
8
6.34
2.38
56.6
34.1
8.18
6.58
ug/l
—
5
8
97
745
1.48
2.35
5.0
3.0
28.35
32.93
e6/l
0.17
75
565
102
793
1.47
2.31
4.7
3.4
2.35
2.36
mmol/l
0.16
89
731
25
135
1.94
2.31
5.1
5.6
24.36
24.31
mmol/l
0.03
25
135
65
460
1.55
2.31
1.8
1.9
—
—
—
0
0
14
60
2.41
2.26
1.1
1.3
—
—
—
0
0
159
1351
1.45
2.22
6.7
5.3
6.49
6.54
mmol/l
0.13
153
1271
251
2369
2.30
2.19
19.2
12.4
—
—
—
0
0
69
501
1.51
2.18
4.1
2.6
4.71
6.31
e6/l
0.62
62
461
37
231
1.70
2.17
4.4
2.3
33.70
29.19
u/l
0.25
30
183
18
88
2.12
2.17
1.8
1.2
—
—
—
0
0
6
14
4.36
2.16
3.0
1.4
50.83
213.86
e6/l
—
6
14
50
339
1.59
2.13
2.1
2.4
68.51
101.69
ug/g
1.15
38
268
54
376
1.55
2.06
1.7
1.7
—
—
—
0
0
32
196
1.72
2.01
2.8
3.4
62.50
72.48
e9/l
1.17
24
144
13
57
2.35
2.01
1.2
1.3
—
—
—
0
0
185
1635
1.44
1.97
4.0
3.3
45.98
41.90
u/l
0.29
175
1558
9
33
2.79
1.95
1.9
1.5
25.30
31.27
ng/l
—
9
33
94
740
1.42
1.94
3.1
2.2
—
—
—
0
0
31
191
1.71
1.91
1.4
1.4
—
—
—
0
0
7
22
3.24
1.89
1.4
1.1
—
—
—
0
0
59
430
1.48
1.81
4.0
2.7
497.68
541.16
mosm/kgh2o
0.98
52
378
48
335
1.53
1.81
2.1
1.7
1054.93
1274.78
nmol/l
0.89
35
253
13
61
2.19
1.74
1.8
2.9
51.38
58.79
%
1.14
13
61
134
1135
1.37
1.74
3.6
3.1
112.90
99.98
ug/l
0.45
124
1062
44
304
1.54
1.74
3.7
3.2
3.93
6.27
e9/l
0.99
37
268
65
489
1.44
1.70
1.4
1.3
13.15
33.10
iu/ml
2.88
12
150
111
919
1.36
1.64
2.9
2.1
—
—
—
0
0
28
176
1.66
1.63
1.3
1.3
43.71
167.95
u/ml
—
7
76
71
548
1.40
1.60
3.5
2.6
321.98
330.97
umol/l
0.24
58
486
20
115
1.80
1.57
4.6
8.2
—
—
—
0
0
243
2302
1.73
1.57
23.0
14.0
26.04
21.82
mg/l
1.08
222
1845
8
33
2.47
1.55
1.6
1.4
—
—
—
0
0
21
125
1.74
1.48
1.2
1.1
—
38.50
—
0
6
7
28
2.54
1.46
2.9
2.2
710.43
1542.29
e6/l
—
7
21
104
866
1.33
1.45
5.7
3.7
135.54
67.94
e6/l
0.29
76
597
5
16
3.16
1.44
5.4
2.6
—
—
—
0
0
119
1011
1.32
1.44
15.3
10.5
1.18
1.16
inr
0.17
104
825
29
191
1.58
1.42
7.9
8.8
—
—
—
0
0
10
46
2.22
1.41
1.8
1.4
—
—
—
0
0
79
633
1.35
1.41
1.7
1.3
0.48
1.96
u/ml
1.78
17
187
34
233
1.53
1.41
5.8
4.8
7.37
7.38
ph
0.38
17
133
41
293
1.47
1.40
7.8
7.6
103.66
104.38
mmol/l
0.45
41
293
14
76
1.89
1.32
6.4
4.5
212.38
204.69
mg/l
—
8
29
13
70
1.90
1.26
3.3
2.5
—
—
—
0
0
40
291
1.44
1.25
1.5
1.4
—
—
—
0
0
6
26
2.34
1.19
1.3
1.2
—
—
—
0
0
15
245
0.59
1.18
1.3
1.4
—
—
—
0
0
124
1081
1.28
1.17
13.0
11.1
0.00
0.00
e9/l
0.43
98
870
0
35
0.00
1.16
0.0
2.6
—
4.94
—
0
28
5
20
2.53
1.15
1.0
1.3
—
—
—
0
0
14
80
1.79
1.15
1.2
1.3
—
—
—
0
0
57
448
1.35
1.15
3.0
2.6
2.42
2.45
mmol/l
1.05
50
414
24
160
1.55
1.14
6.1
3.5
—
—
—
0
0
256
2494
1.99
1.13
32.4
21.9
256.82
254.97
e9/l
0.16
251
2452
70
569
1.31
1.12
1.9
1.5
2.12
2.28
g/l
0.33
39
350
21
136
1.59
1.12
1.2
2.3
—
—
—
0
0
66
533
1.32
1.11
1.9
1.9
1.66
1.14
mg/l
0.33
51
415
23
154
1.54
1.08
1.4
1.3
32.74
25.84
iu/l
0.34
17
127
32
231
1.44
1.06
7.2
9.8
7.41
7.41
ph
0.07
19
135
32
231
1.44
1.06
2.2
1.5
—
—
—
0
0
9
46
1.99
1.04
2.7
1.8
—
—
—
0
0
7
34
2.09
1.03
1.1
1.1
—
—
—
0
0
242
2324
1.52
1.03
24.8
16.3
3.93
3.95
mmol/l
0.47
236
2273
256
2497
1.95
1.02
32.6
21.9
6.47
6.61
e9/l
0.53
248
2443
223
2113
1.36
1.02
6.7
6.1
39.52
38.94
mmol/mol
0.34
204
2001
256
2496
1.96
1.01
32.6
21.8
4.42
4.50
e12/l
1.69
248
2446
5
23
2.20
0.98
1.0
1.1
116.80
103.17
pmol/l
—
5
23
5
23
2.20
0.98
2.2
2.4
29.24
39.45
%
—
5
23
31
226
1.42
0.98
7.3
9.9
2.06
0.76
mmol/l
1.44
25
196
0
30
0.00
0.98
0.0
2.4
—
1.19
—
0
30
0
30
0.00
0.98
0.0
2.4
—
3.97
—
0
30
0
30
0.00
0.98
0.0
2.4
—
106.03
—
0
30
29
211
1.42
0.93
1.6
1.4
—
—
—
0
0
241
2321
1.46
0.91
24.5
16.2
139.28
139.83
mmol/l
2.51
236
2276
27
198
1.41
0.84
2.2
2.4
6.44
6.18
ph
0.72
17
126
8
48
1.69
0.79
1.0
1.1
—
—
—
0
0
8
48
1.69
0.79
1.4
1.8
—
—
—
0
0
9
55
1.66
0.74
1.6
1.2
—
—
—
0
0
7
40
1.77
0.72
1.0
1.1
—
—
—
0
0
30
232
1.33
0.70
3.7
4.5
21.57
38.31
ug/l
0.20
20
189
33
260
1.31
0.68
2.9
3.5
1.50
1.78
%
1.58
26
234
5
28
1.80
0.66
1.0
1.4
—
—
—
0
0
5
28
1.80
0.66
4.0
9.6
10.98
11.14
%
—
5
28
16
114
1.43
0.60
1.1
1.1
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
1.54
—
0
16
6
36
1.68
0.57
1.2
1.7
—
—
—
0
0
82
732
1.17
0.55
7.6
6.5
—
—
—
0
0
13
91
1.45
0.54
2.8
1.7
—
—
—
0
0
118
1088
1.15
0.52
3.5
2.7
—
—
estimate
—
0
0
27
216
1.28
0.52
4.9
4.9
0.00
0.07
%
—
6
54
204
1961
1.18
0.50
25.7
18.2
332.45
332.40
g/l
0.03
204
1953
66
584
1.17
0.49
5.5
4.9
—
—
—
0
0
50
433
1.19
0.48
5.3
3.2
206.37
208.52
ng/l
0.00
38
310
134
1253
1.14
0.47
4.5
3.7
0.00
0.00
estimate
-0.00
27
263
20
253
0.77
0.47
1.4
1.6
—
—
—
0
0
35
293
1.22
0.47
1.5
1.3
—
—
—
0
0
18
138
1.33
0.47
1.3
1.2
—
—
—
0
0
5
84
0.59
0.46
6.4
9.6
—
—
—
0
0
10
69
1.47
0.45
1.1
1.1
—
—
—
0
0
134
1260
1.13
0.42
4.5
3.8
0.14
0.01
estimate
0.43
22
244
61
544
1.16
0.42
4.6
3.5
—
0.33
—
0
6
0
15
0.00
0.41
0.0
1.1
—
0.48
—
0
8
0
16
0.00
0.41
0.0
2.1
—
6.55
—
0
11
5
36
1.40
0.38
2.8
2.1
—
—
—
0
0
131
1238
1.12
0.36
4.5
3.7
0.00
0.00
estimate
0.50
26
260
25
209
1.22
0.35
4.8
4.4
0.83
0.47
%
—
6
59
12
91
1.33
0.34
1.2
1.6
—
8.66
—
0
21
20
164
1.24
0.33
1.4
1.3
—
—
—
0
0
6
86
0.69
0.33
1.2
1.1
—
0.58
—
0
12
6
87
0.68
0.33
1.2
1.1
1.50
1.57
g/l
—
6
87
6
88
0.67
0.33
1.2
1.1
0.97
0.90
g/l
—
6
88
6
47
1.28
0.32
2.0
2.1
—
—
—
0
0
6
47
1.28
0.32
4.0
2.0
7.35
4.88
mmol/24h
—
6
39
7
55
1.28
0.30
3.3
6.7
74.46
58.71
%
—
7
55
16
130
1.25
0.29
1.4
1.7
—
—
—
0
0
51
463
1.13
0.28
1.9
1.8
411.82
434.41
pmol/l
0.32
40
392
25
216
1.17
0.26
3.5
2.2
0.00
0.06
estimate
—
5
50
14
114
1.24
0.25
2.1
2.2
—
—
—
0
0
64
689
0.91
0.25
1.3
1.4
—
—
—
0
0
224
2198
1.13
0.25
5.5
4.9
5.85
5.85
mmol/l
0.01
205
2049
9
76
1.19
0.25
1.6
1.7
—
—
—
0
0
24
209
1.16
0.24
4.9
4.7
0.00
0.13
%
—
5
56
12
97
1.25
0.23
2.5
2.9
19.42
21.33
s
0.95
12
90
15
125
1.21
0.23
3.9
2.2
0.00
0.02
estimate
—
5
46
25
220
1.15
0.22
4.8
4.5
1.50
0.79
%
—
6
67
0
12
0.00
0.21
0.0
2.8
—
2.65
—
0
12
0
13
0.00
0.21
0.0
1.1
—
170.51
—
0
13
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
89
848
1.07
0.19
3.6
3.5
29.73
30.22
ng/l
0.02
64
559
6
52
1.16
0.19
2.5
3.6
22.50
17.59
u/ml
—
6
52
93
973
0.93
0.19
2.8
3.0
—
—
—
0
0
23
205
1.13
0.17
1.2
1.8
3.98
3.42
mmol/l
1.11
13
154
7
62
1.13
0.17
3.6
3.3
3.87
3.93
mmol/l
—
7
62
232
2291
1.11
0.17
6.2
5.6
2.78
2.78
mmol/l
0.02
208
2149
26
236
1.11
0.15
1.5
1.8
—
—
—
0
0
9
79
1.14
0.15
1.3
2.1
—
—
—
0
0
29
266
1.10
0.14
3.0
3.2
0.83
0.78
ug/l
0.13
21
156
27
294
0.91
0.14
1.4
1.5
—
—
—
0
0
105
1017
1.05
0.13
3.8
3.4
6.41
6.21
ph
1.06
59
571
228
2259
1.07
0.10
5.7
4.9
1.50
1.51
mmol/l
0.14
203
2114
106
1033
1.04
0.10
2.5
1.9
1.37
1.35
mmol/l
0.08
79
885
67
694
0.95
0.09
5.2
3.8
0.00
0.01
estimate
0.74
25
247
69
714
0.95
0.09
5.5
3.9
32.01
6.76
mg/mmol
2.10
42
423
68
703
0.96
0.09
4.8
3.2
145.98
36.33
mg/l
1.82
47
427
10
113
0.88
0.08
1.4
1.5
—
—
—
0
0
7
64
1.10
0.08
1.3
1.6
—
—
—
0
0
54
559
0.96
0.07
4.1
3.8
1.01
1.02
kg/l
0.85
37
366
79
773
1.03
0.05
4.4
3.1
7.12
7.67
mmol/l
0.52
64
657
10
90
1.12
0.05
1.4
1.5
—
—
—
0
0
14
130
1.08
0.04
6.1
4.3
0.61
0.64
%
0.17
14
130
96
945
1.02
0.04
4.2
3.6
0.07
0.04
estimate
0.17
27
218
10
109
0.91
0.04
1.4
1.5
—
—
—
0
0
13
139
0.93
0.03
6.3
9.5
0.63
0.64
%
0.04
13
139
71
699
1.02
0.03
3.5
3.2
0.04
0.01
estimate
0.33
25
211
228
2271
1.03
0.02
5.7
4.9
4.73
4.74
mmol/l
0.04
210
2136
15
144
1.04
0.00
1.0
1.1
—
—
—
0
0
213
2136
0.99
0.00
4.9
4.1
1.22
1.27
mmol/l
0.68
196
1987
19
188
1.01
0.00
3.9
3.5
—
—
—
0
0
11
111
0.99
0.00
1.4
1.5
—
—
—
0
0
11
111
0.99
0.00
1.4
1.5
—
—
—
0
0
13
131
0.99
0.00
6.5
4.3
1.54
1.19
%
1.08
13
131
14
144
0.97
0.00
6.1
9.2
1.18
1.38
%
0.55
14
144
0
8
0.00
0.00
0.0
1.1
—
47.94
—
0
8
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
7
74
0.94
-0.00
1.3
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
-0.00
1.2
1.1
0.92
0.28
u/ml
—
5
30
8
86
0.93
-0.00
1.5
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
1.16
—
0
7
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
5
49
1.02
-0.00
9.6
2.1
11.34
6.99
pmol/l
—
5
49
0
9
0.00
-0.00
0.0
3.6
—
55.17
—
0
9
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
11
110
1.00
-0.00
1.4
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
9.01
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint L12_NAIL_LYSIS and mortality.

Females

Parameter HR [95% CI] p-value
L12_NAIL_LYSIS 1.582 [1.07, 2.33] 0.02
Birth year 0.995 [0.99, 1.0] 0.282

During the follow-up period (1.1.1998 — 31.12.2019), 73 out of 827 females with L12_NAIL_LYSIS died.

Males

Parameter HR [95% CI] p-value
L12_NAIL_LYSIS 1.692 [1.09, 2.62] 0.018
Birth year 0.985 [0.98, 0.99] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 70 out of 543 males with L12_NAIL_LYSIS died.

Mortality risk

Mortality risk for people of age

years, who have L12_NAIL_LYSIS.

N-year risk Females Males
1 0.189% 0.308%
5 0.914% 1.598%
10 2.268% 4.152%
15 4.445% 7.92%
20 7.88% 13.34%

Relationships between endpoints

↥

Index endpoint: L12_NAIL_LYSIS – Onycholysis

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data