Polyp of middle ear

H8_POLYPMIDD

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — H74.4 Cause of death: ICD-10 — H74.4 2 out of 7 registries used, show all original rules.	65
4. Check minimum number of events None	65
5. Include endpoints None	65
6. Filter based on genotype QC (FinnGen only)	55

Control definitions (FinnGen only)

Control exclude: H8_MIDDLEMASTOID

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: H74
Name in latin: Polypus auris mediae

NAME	H8_POLYPMIDD
CONTROL_EXCLUDE	H8_MIDDLEMASTOID
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	H744
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	H744
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Polyp of middle ear based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	794	336	456
Only index persons	694	295	399
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.02
Median age at first event (years)
Whole population	11.75	10.66	12.26
Only index persons	13.86	11.53	15.58

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	55	30	25
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	48.80	45.36	52.92

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
60: Matched controls
600

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

H74.4

ICD-10 Finland

Polyp of middle ear

+∞

86.1

H65.3

ICD-10 Finland

Chronic mucoid otitis media

+∞

25.9

DCA20

NOMESCO Finland

Insertion of ventilating tube through tympanic membrane

+∞

21.1

H72.0

ICD-10 Finland

Central perforation of tympanic membrane

+∞

19.9

H65.2

ICD-10 Finland

Chronic serous otitis media

+∞

14.1

H71

ICD-10 Finland

Cholesteatoma of middle ear

+∞

14.1

UDC00

NOMESCO Finland

Ear microscopy

14.8

13.3

H60.9

ICD-10 Finland

Otitis externa, unspecified

17.7

11.0

Z01.1

ICD-10 Finland

Examination of ears and hearing

6.0

9.8

EMB30

NOMESCO Finland

Adenotomy

117.8

9.7

H66.9

ICD-10 Finland

Otitis media, unspecified

10.2

9.0

DC1AD

NOMESCO Finland

Temporalbone CT

+∞

7.4

H65.1

ICD-10 Finland

Other acute nonsuppurative otitis media

+∞

7.4

J01EE02

ATC

sulfadiazine and trimethoprim; systemic

4.4

7.2

H90.6

ICD-10 Finland

Mixed conductive and sensorineural hearing loss, bilateral

77.8

6.6

J35.2

ICD-10 Finland

Hypertrophy of adenoids

30.2

6.4

H74.1

ICD-10 Finland

Adhesive middle ear disease

+∞

6.4

H66.3

ICD-10 Finland

Other chronic suppurative otitis media

+∞

6.4

H70.1

ICD-10 Finland

Chronic mastoiditis

+∞

6.4

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3007853) Bacteria identified in Skin by Aerobe culture

3.37

3.57

3.1

1.5

—

(3000494) Fungus identified in Specimen by Culture

2.79

2.52

1.6

1.4

—

(3022313) Gas panel - Capillary blood

3.43

2.50

3.1

7.6

—

(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation

2.94

2.44

2.7

6.3

0.16

1.54

mmol/l

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

4.63

2.21

1.3

1.9

—

(3004588) Protein electrophoresis panel - Serum or Plasma

2.84

1.89

3.7

1.5

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

4.44

1.86

1.2

2.0

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

2.92

1.80

2.5

2.3

96.75

140.68

ng/l

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

0.00

1.80

0.0

3.1

—

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

2.38

1.68

6.9

4.5

37.43

33.33

—

(40761536) Microorganisms panel - Urine sediment

0.00

1.39

0.0

4.4

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

0.00

1.37

0.0

1.2

—

(1761868) Lipid panel - Serum or Plasma

187

0.50

1.26

2.8

3.0

—

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

0.00

1.20

0.0

2.3

—

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

0.00

1.18

0.0

2.8

—

1.21

—

(3003694) ABO and Rh group [Type] in Blood

143

0.49

1.12

1.3

1.5

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.50

1.11

1.2

1.6

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

118

1.75

1.07

3.6

2.7

—

(3013512) EKG study

162

1.68

1.06

4.9

3.4

—

(3044640) Blood type and Crossmatch panel - Blood

155

1.66

1.01

3.4

2.8

—

(3023323) Follitropin [Units/volume] in Serum or Plasma

0.00

1.00

0.0

1.6

—

26.88

—

(3025941) Bacteria identified in Stool by Culture

0.00

1.00

0.0

1.2

—

(21494755) Public health laboratory ask at order entry panel

1.90

1.00

1.6

1.4

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

2.35

0.96

1.2

1.4

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

150

1.62

0.90

3.6

3.2

669.89

931.64

ng/l

0.39

116

(3009508) Creatinine [Moles/volume] in Urine

178

1.58

0.88

3.8

3.0

6.28

7.63

mmol/l

1.00

154

(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum

0.00

0.81

0.0

1.2

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

0.00

0.80

0.0

1.6

—

(3041096) Erythrocytes [Presence] in Urine by Automated

163

0.60

0.73

2.0

3.6

—

0.00

estimate

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

232

1.48

0.73

2.3

3.1

82.86

107.06

ug/l

0.53

215

(3015736) pH of Urine

225

0.66

0.69

3.0

3.6

6.23

6.24

0.02

131

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.67

0.68

1.5

1.8

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.61

0.67

1.5

1.9

—

(3002256) Pathology report gross observation

1.62

0.62

1.4

1.2

—

(3025245) SCL-70 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.61

0.0

1.1

—

(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum

0.00

0.61

0.0

1.4

—

320.80

—

(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma

0.00

0.61

0.0

1.5

—

37.00

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.60

0.0

1.2

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

0.00

0.59

0.0

2.5

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

1.69

0.57

5.0

2.3

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

435

1.52

0.56

5.0

4.2

1.29

1.24

mmol/l

0.23

395

(40758558) Short blood count panel - Blood

175

0.67

0.55

4.4

5.4

—

(40761511) CBC panel - Blood by Automated count

533

0.63

0.54

15.4

13.2

—

(3012516) Albumin [Mass/volume] in Urine

158

1.40

0.51

4.2

3.0

103.47

64.63

mg/l

0.19

112

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.52

0.50

4.5

2.3

—

(3021960) Folate [Moles/volume] in Serum or Plasma

140

1.41

0.50

1.6

1.7

14.49

20.47

nmol/l

1.43

127

(3023368) Bacteria identified in Blood by Culture

132

1.40

0.47

4.0

4.4

—

(3020682) Albumin/Creatinine [Ratio] in Urine

161

1.36

0.45

4.8

3.5

42.73

10.36

mg/mmol

0.38

103

(3000764) Benzodiazepines [Presence] in Urine

1.67

0.44

1.2

1.3

—

(3016879) Cocaine [Presence] in Urine

1.67

0.44

1.2

1.3

—

(3027008) Opiates [Presence] in Urine

1.56

0.42

1.2

—

(3028300) Cannabinoids [Presence] in Urine

1.56

0.42

1.2

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.41

0.0

6.1

—

(3007080) Epstein Barr virus nuclear IgG Ab [Units/volume] in Serum

0.00

0.41

0.0

1.4

—

138.50

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.41

0.0

1.1

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

0.00

0.41

0.0

1.4

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

455

1.42

0.41

5.8

4.8

1.47

1.44

mmol/l

0.26

415

(3014765) Yersinia sp identified in Stool by Organism specific culture

0.00

0.40

0.0

1.2

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

0.00

0.40

0.0

1.2

—

(42529406) Shigella sp [Presence] in Stool by Culture

0.00

0.40

0.0

1.2

—

(3030467) Casts [#/volume] in Urine by Automated count

144

0.71

0.39

3.0

0.18

0.61

e6/l

—

105

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.48

0.37

5.2

2.5

—

(4010399) Spirometry for bronchospasm with prolonged evaluation after bronchodilator

1.48

0.37

1.5

1.6

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

204

1.29

0.37

2.2

2.0

95.45

94.62

pmol/l

0.04

(3000492) Spirometry study

1.40

0.35

1.0

1.4

—

(3042936) Bacteria identified in Isolate by Culture

1.40

0.32

1.9

1.6

—

(3026782) Osmolality of Urine

106

0.72

0.32

2.9

3.2

483.13

532.53

mosm/kgh2o

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

469

0.77

0.31

5.4

4.9

6.00

5.92

mmol/l

0.13

431

(3000850) Epithelial cells [#/volume] in Urine

119

0.71

0.31

2.0

2.5

7.28

6.06

e6/l

—

111

(42870588) Differential panel, method unspecified - Blood

181

1.25

0.28

4.8

6.9

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.29

0.27

4.1

2.2

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

350

1.23

0.27

2.8

3.2

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

518

1.42

0.26

14.8

15.5

21.41

24.14

mg/l

0.27

421

(3013650) Neutrophils [#/volume] in Blood by Automated count

311

1.22

0.25

10.0

10.1

4.11

3.98

e9/l

0.12

270

(40768804) Tissue Pathology biopsy report

183

1.23

0.25

2.2

1.9

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

222

1.22

0.25

2.6

87.89

75.96

nmol/l

0.85

203

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.34

0.24

1.0

1.4

—

(3028026) IgM [Mass/volume] in Serum or Plasma

1.24

0.22

2.4

1.6

1.07

1.10

g/l

—

(3014111) Lactate [Moles/volume] in Serum or Plasma

1.21

0.22

7.6

11.1

1.08

1.60

mmol/l

—

(3028626) Oxygen [Partial pressure] in Capillary blood

1.21

0.22

3.0

6.0

8.44

9.01

kpa

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

0.21

0.0

1.5

—

91.08

—

(3024928) Oxygen saturation in Venous blood

0.00

0.21

0.0

6.3

—

66.17

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.21

0.0

1.6

—

(3013290) Carbon dioxide [Partial pressure] in Blood

0.00

0.21

0.0

2.4

—

5.28

—

(3035637) Corticotropin [Mass/volume] in Plasma

0.00

0.21

0.0

1.6

—

16.80

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

0.21

0.0

1.3

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.21

0.0

1.4

—

(3027315) Oxygen [Partial pressure] in Blood

0.00

0.21

0.0

2.4

—

9.09

—

(3010130) Cytomegalovirus IgG Ab [Units/volume] in Serum or Plasma

0.00

0.21

0.0

1.8

—

109.40

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

0.21

0.0

1.2

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.2

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

0.00

0.21

0.0

1.8

—

(3044290) Cell count panel - Cerebral spinal fluid

0.00

0.21

0.0

1.7

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

0.00

0.21

0.0

1.8

—

(3018095) Leukocytes [#/volume] in Urine

194

0.83

0.20

4.1

3.8

62.13

117.44

e6/l

0.32

138

(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma

1.20

0.20

4.2

16.07

11.47

ug/l

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

469

1.24

0.19

6.4

5.7

2.61

2.72

mmol/l

0.44

433

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

459

1.23

0.19

5.7

5.0

4.64

4.58

mmol/l

0.18

422

(36304419) Bacteria [Presence] in Urine

141

0.81

0.19

2.8

3.0

—

estimate

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.19

0.18

3.3

8.9

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

0.70

0.18

9.8

9.0

104.40

104.61

mmol/l

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

218

1.17

0.17

3.7

5.5

34.00

35.60

g/l

0.44

208

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

131

1.19

0.16

2.3

2.9

3.08

2.69

mg/l

—

119

(3031040) Bacteria [#/volume] in Urine by Automated count

319

1.15

0.15

3.6

4.5

—

53.20

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

122

1.19

0.15

1.8

1.6

—

(40760892) CBC W Ordered Manual Differential panel - Blood

127

0.84

0.14

2.5

5.1

—

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

278

0.89

0.12

6.2

6.7

9.62

15.70

umol/l

2.17

266

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

397

0.88

0.12

5.1

4.1

14.43

14.83

pmol/l

0.38

366

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

227

0.88

0.11

4.2

3.2

—

estimate

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

125

1.16

0.11

5.5

4.4

13.94

23.00

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

175

1.13

0.10

2.9

3.2

—

(3026008) Bacteria identified in Urine by Culture

134

0.87

0.10

1.3

3.7

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.10

0.09

1.7

1.5

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

538

1.27

0.08

20.5

18.9

75.87

74.84

umol/l

0.10

529

(3003396) Base excess in Arterial blood by calculation

0.76

0.08

8.0

9.6

3.36

1.73

mmol/l

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.07

0.08

1.9

1.8

—

(3002582) Erythrocytes [#/volume] in Urine

173

0.90

0.08

3.1

3.0

19.35

28.35

e6/l

0.38

134

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

0.87

0.07

1.1

1.4

—

(3037467) Urinalysis macro (dipstick) panel - Urine

348

1.09

0.06

3.5

4.7

—

(3007164) IgA [Mass/volume] in Serum or Plasma

140

1.10

0.05

2.9

1.5

7.90

2.10

g/l

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

102

1.10

0.03

1.5

1.9

440.00

483.37

pmol/l

0.21

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

444

1.05

0.00

7.8

6.1

42.85

39.75

mmol/mol

0.61

419

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

1.05

0.00

1.1

1.3

—

35.77

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

186

1.03

0.00

5.4

4.2

21.85

38.95

ng/l

0.51

134

(46235355) HIV 1 and 2 tests - Meaningful Use set

108

1.02

0.00

2.3

1.9

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.03

0.00

1.7

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.95

0.00

1.5

1.3

—

(3018677) aPTT in Platelet poor plasma by Coagulation assay

0.92

-0.00

2.4

2.5

26.50

28.53

—

(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(36660697) Celiac disease serology panel - Serum

0.96

-0.00

1.3

1.1

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

0.00

-0.00

0.0

1.3

—

(3023709) Somatotropin [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

5.7

—

1.18

—

(3017817) Protein [Mass] in Urine collected for unspecified duration

0.00

-0.00

0.0

1.7

—

432.33

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

-0.00

0.0

1.1

—

(3005719) IgG [Mass/volume] in Serum or Plasma

1.02

-0.00

2.4

2.1

8.62

10.11

g/l

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

3.4

—

211.53

—

(3012413) Glucose [Moles/volume] in Serum or Plasma --2 hours post meal

0.00

-0.00

0.0

1.5

—

11.92

—

(3027901) Hemoglobin [Mass/volume] in Arterial cord blood

0.00

-0.00

0.0

1.0

—

178.20

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

16.71

—

(3012494) Peanut IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.3

—

0.25

—

(3017704) Immunofixation for Urine

0.00

-0.00

0.0

1.0

—

(3011648) Oxygen content in Venous blood

0.00

-0.00

0.0

8.0

—

11.65

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

-0.00

0.0

1.2

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

-0.00

0.0

1.5

—

(40768795) Lymph node Pathology biopsy report

0.00

-0.00

0.0

1.1

—

(3032700) Glomerular basement membrane Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.1

—

(3000991) Gas panel - Venous blood

1.02

-0.00

7.3

8.6

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

-0.00

0.0

1.0

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(3006257) Acetylcholine receptor Ab [Moles/volume] in Serum

0.00

-0.00

0.0

1.3

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

-0.00

0.0

1.0

—

(3007695) Herpes simplex virus 2 IgG Ab [Presence] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3045716) Anion gap in Serum or Plasma by calculation

0.00

-0.00

0.0

1.8

—

10.38

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

-0.00

0.0

1.4

—

10.04

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

-0.00

0.0

1.2

—

6.78

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.00

-0.00

1.0

1.4

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

-0.00

0.0

1.1

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

2.3

—

(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3012447) Hantavirus puumala IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

-0.00

0.0

1.0

—

(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

0.00

-0.00

0.0

1.1

—

201.94

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

-0.00

0.0

1.2

—

(3028679) Herpes simplex virus Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3045788) Cell count panel - Pleural fluid

0.00

-0.00

0.0

1.2

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(40759850) Jo-1 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(42870308) Desmosome IgG Ab [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

2.4

—

(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay

0.00

-0.00

0.0

1.0

—

(3031072) Herpes simplex virus 1 IgG Ab [Presence] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(40768806) Pleura Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

-0.00

0.0

3.8

—

(40765096) Chromosome analysis panel by Banding

0.00

-0.00

0.0

1.2

—

(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay

0.00

-0.00

0.0

1.0

—

(3044927) Protein electrophoresis panel - Urine

0.00

-0.00

0.0

1.2

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

-0.00

0.0

1.2

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

480

1.00

-0.00

5.8

5.0

2.22

1.91

mu/l

0.78

441

(3011897) Casein IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.3

—

0.57

—

(3018333) Ribosomal P Ab [Presence] in Serum

0.00

-0.00

0.0

1.3

—

(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

-0.00

0.0

1.4

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3036428) Adenosine deaminase [Enzymatic activity/volume] in Pleural fluid

0.00

-0.00

0.0

1.2

—

16.60

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.00

-0.00

0.0

1.1

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

-0.00

0.0

2.6

—

0.40

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

-0.00

0.0

1.0

—

32.25

—

(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(37208534) Antinuclear antibody arbitrary concentration in serum

0.00

-0.00

0.0

1.0

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

-0.00

0.0

2.0

—

(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

88.60

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(40768441) Liver Pathology biopsy report

0.00

-0.00

0.0

1.8

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

-0.00

0.0

1.4

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

-0.00

0.0

1.3

—

(3003434) Protein [Mass/volume] in Pleural fluid

0.00

-0.00

0.0

1.1

—

35.31

—

(3052649) Adenosine deaminase [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

15.40

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

42.09

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

0.00

-0.00

0.0

1.1

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

-0.00

0.0

1.3

—

(3035715) Granulocytes [#/volume] in Blood

0.00

-0.00

0.0

1.9

—

4.82

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

-0.00

0.0

1.2

—

(3023410) Appearance of Cerebral spinal fluid

0.00

-0.00

0.0

2.1

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

5.1

—

2.72

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.2

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

Mortality – FinRegistry

↥

Association

Association between endpoint H8_POLYPMIDD and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have H8_POLYPMIDD.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: H8_POLYPMIDD – Polyp of middle ear

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Polyp of middle ear

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints