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Lens-induced iridocyclitis

DOID Endpoint Browser PheWeb

H7_IRIDOLENS

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H20.2
  • Cause of death: ICD-10 — H20.2

2 out of 7 registries used, show all original rules.

71

4. Check minimum number of events

None

71

5. Include endpoints

None

71

6. Filter based on genotype QC (FinnGen only)

61

Control definitions (FinnGen only)

Control exclude
H7_SCLERACORNEA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H20
Name in latin
Iridocyclitis phakogenes

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 330 171 157
Only index persons 311 165 146
Unadjusted period prevalence (%)
Whole population 0.00 0.00 0.00
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 53.04 53.69 52.23
Only index persons 53.04 53.29 52.76

-FinnGen-

Key figures

All Female Male
Number of individuals 61 35 26
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 60.64 60.57 60.72

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
64
Matched controls
640
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H20.2
ICD-10 Finland
Lens-induced iridocyclitis
+∞
91.9
64
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
901.4
43.7
38
*
H20.1
ICD-10 Finland
Chronic iridocyclitis
+∞
16.3
15
*
S01BA04
ATC
prednisolone; ophthalmic
43.9
11.8
14
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
6.6
11.0
23
50
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic
48.3
10.4
12
*
S01ED01
ATC
timolol; ophthalmic
15.9
8.9
14
11
S01BC03
ATC
diclofenac; ophthalmic
+∞
8.5
8
*
S01BA01
ATC
dexamethasone; ophthalmic
18.1
8.1
12
8
H26.4
ICD-10 Finland
After-cataract
5.4
7.6
18
43
S01EA03
ATC
apraclonidine; ophthalmic
+∞
7.4
7
*
Z96.1
ICD-10 Finland
Presence of intraocular lens
4.7
7.2
21
60
S01FA04
ATC
cyclopentolate; ophthalmic
44.9
6.9
8
*
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
25.7
6.9
9
*
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
77.2
6.6
7
*
H26.2
ICD-10 Finland
Complicated cataract
30.0
6.4
8
*
L04AX03
ATC
methotrexate; systemic
6.2
6.3
17
35
S01EE01
ATC
latanoprost; ophthalmic
6.9
6.2
15
27
CJB10
NOMESCO Finland
Laser discission of secondary cataract
5.9
6.1
17
37

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
27
117
3.26
4.88
6.3
6.8
—
—
—
0
0
36
187
3.11
4.75
5.2
4.0
7.39
7.40
ph
0.35
26
133
47
293
3.27
4.37
11.4
6.1
0.20
0.20
e9/l
0.02
47
256
45
279
3.06
4.12
11.6
6.0
0.56
0.58
e9/l
0.37
45
239
45
279
3.06
4.12
11.6
6.0
0.05
0.04
e9/l
1.57
45
237
45
285
2.95
3.86
11.9
6.0
1.90
1.90
e9/l
0.00
45
254
10
22
5.18
3.60
1.0
1.1
—
—
—
0
0
48
322
2.96
3.56
12.3
10.9
3.92
4.25
e9/l
0.54
48
279
46
305
2.81
3.44
6.7
7.0
1.20
1.21
mmol/l
0.60
38
265
31
172
2.56
3.31
3.4
3.1
0.40
0.43
e6/l
0.06
25
126
31
173
2.54
3.26
6.9
4.1
0.00
0.03
estimate
0.49
11
60
20
91
2.74
3.15
4.6
6.8
104.25
103.68
mmol/l
0.22
20
91
29
161
2.47
3.04
3.4
3.1
—
—
estimate
—
0
0
37
232
2.41
2.94
4.4
4.0
343.55
94.94
e6/l
0.35
31
162
10
28
4.03
2.93
2.8
4.2
36.88
36.96
°c
—
10
28
8
18
4.92
2.90
1.0
1.1
—
—
—
0
0
6
10
6.48
2.76
1.0
1.1
—
—
—
0
0
12
42
3.28
2.73
4.4
1.9
718.42
199.11
ng/l
0.39
12
35
39
260
2.28
2.57
13.3
5.9
0.65
0.62
%
0.16
39
245
39
260
2.28
2.57
12.4
6.2
55.80
58.89
%
1.12
39
249
31
190
2.22
2.48
13.2
5.3
—
—
—
0
0
39
263
2.24
2.46
13.1
5.9
2.86
2.69
%
0.24
39
249
7
17
4.48
2.43
2.1
3.9
3.69
3.92
mmol/l
—
7
17
39
264
2.22
2.43
13.3
6.1
8.51
8.55
%
0.03
39
251
36
236
2.20
2.43
3.6
3.6
24.82
46.51
ng/l
0.74
30
169
5
8
6.66
2.41
9.6
7.5
—
—
—
0
0
11
41
3.03
2.35
3.2
2.0
8.80
9.52
g/l
0.35
11
36
44
316
2.26
2.33
6.3
4.1
0.00
0.00
estimate
-0.00
13
63
39
267
2.18
2.33
13.3
6.2
29.63
26.61
%
1.10
39
256
11
43
2.88
2.21
2.4
4.1
—
—
—
0
0
12
50
2.72
2.18
1.5
2.1
4.41
5.68
ug/l
0.28
12
43
50
384
2.38
2.17
6.9
4.5
—
—
—
0
0
43
311
2.17
2.17
6.4
4.1
0.00
0.00
estimate
-0.00
13
65
43
311
2.17
2.17
6.4
4.0
0.00
0.00
estimate
-0.00
13
65
15
71
2.45
2.13
1.3
1.5
434.29
736.00
titre
—
7
15
6
16
4.02
1.98
3.7
1.7
1.37
1.09
g/l
—
6
16
6
16
4.02
1.98
3.7
1.6
0.21
0.20
g/l
—
6
16
5
11
4.83
1.98
9.2
2.1
7.39
7.41
ph
—
5
11
15
75
2.31
1.88
2.7
8.6
7.44
7.42
ph
—
9
46
13
61
2.42
1.87
2.4
3.0
7.38
7.40
ph
—
7
38
5
12
4.42
1.86
8.2
2.2
—
—
—
0
0
34
236
1.94
1.80
6.9
4.1
0.00
0.05
estimate
0.49
13
55
19
107
2.10
1.80
1.9
2.3
21.68
20.75
%
0.13
19
101
12
57
2.36
1.67
1.5
1.5
—
—
—
0
0
27
178
1.89
1.63
4.2
3.3
—
—
—
0
0
10
45
2.45
1.55
7.5
3.2
—
—
—
0
0
35
254
1.83
1.55
5.5
3.7
6.34
6.24
ph
0.15
16
143
39
294
1.84
1.51
17.9
11.7
1.23
1.22
inr
0.04
31
242
27
182
1.84
1.50
7.4
7.3
—
—
—
0
0
10
46
2.39
1.49
3.1
9.7
1.32
1.50
%
—
10
46
47
377
1.93
1.48
7.6
4.6
—
42.62
—
0
8
26
175
1.82
1.44
4.0
4.2
—
—
—
0
0
10
47
2.34
1.42
5.4
3.7
—
—
—
0
0
20
125
1.87
1.39
7.8
4.3
1.02
1.02
kg/l
0.63
13
85
0
33
0.00
1.20
0.0
1.0
—
—
—
0
0
36
278
1.67
1.18
2.3
2.9
—
—
estimate
—
0
0
24
168
1.69
1.12
4.6
3.7
0.00
0.00
estimate
-0.00
12
52
7
32
2.33
1.12
1.7
2.8
0.81
0.60
%
—
7
32
27
196
1.65
1.10
2.0
2.4
—
—
—
0
0
7
33
2.26
1.09
1.7
2.8
1.31
1.30
%
—
7
33
9
47
2.06
1.08
1.1
1.3
—
—
—
0
0
12
70
1.88
1.01
2.5
3.7
4.01
4.37
e9/l
0.19
12
62
53
464
1.83
0.99
29.5
21.4
13.70
13.86
%
0.41
53
459
7
37
2.00
0.97
1.4
1.4
—
—
—
0
0
13
79
1.81
0.97
1.5
1.7
—
—
—
0
0
12
71
1.85
0.97
1.6
1.5
—
—
—
0
0
8
45
1.89
0.88
2.1
2.8
0.23
0.21
g/l
—
8
40
8
45
1.89
0.88
5.1
3.2
97.75
68.81
ng/l
—
8
40
8
46
1.84
0.86
3.1
3.4
1.22
1.22
mmol/l
—
8
40
50
437
1.66
0.86
34.8
22.8
331.88
331.60
g/l
0.09
50
437
25
188
1.54
0.85
5.3
4.2
3.94
11.25
mg/mmol
1.42
16
117
11
67
1.77
0.81
3.5
2.7
16.45
6.69
umol/l
0.43
11
59
9
55
1.74
0.78
4.1
9.2
—
—
—
0
0
7
41
1.79
0.72
8.9
6.6
25.90
25.83
mmol/l
—
7
41
5
27
1.92
0.70
1.0
1.2
—
—
—
0
0
32
262
1.44
0.69
2.3
2.1
94.36
98.60
pmol/l
0.17
19
128
24
186
1.46
0.69
4.3
3.5
34.79
62.67
mg/l
0.74
16
124
0
23
0.00
0.59
0.0
3.9
—
269.10
—
0
10
7
45
1.62
0.51
3.6
2.2
—
—
—
0
0
7
47
1.55
0.49
1.0
1.4
—
—
—
0
0
5
84
0.56
0.49
1.6
1.2
—
—
—
0
0
8
59
1.41
0.43
4.8
2.0
541.13
423.80
nmol/l
—
8
54
10
71
1.48
0.42
1.4
1.5
—
—
—
0
0
13
98
1.41
0.41
1.2
1.4
0.98
8.58
u/ml
—
8
38
0
17
0.00
0.41
0.0
1.3
—
—
—
0
0
9
67
1.40
0.40
5.8
3.6
74.67
71.41
e9/l
—
9
52
9
70
1.33
0.39
1.4
1.4
—
—
—
0
0
6
42
1.47
0.37
2.8
2.2
—
—
—
0
0
11
140
0.74
0.32
1.5
1.3
—
0.86
—
0
38
12
94
1.34
0.31
1.4
1.8
—
—
—
0
0
8
64
1.29
0.29
1.4
1.2
—
—
—
0
0
59
566
1.54
0.27
27.4
20.0
3.98
3.98
mmol/l
0.01
59
556
59
566
1.54
0.27
26.7
20.0
139.42
139.69
mmol/l
0.30
59
558
14
117
1.25
0.23
1.7
1.5
2.17
2.38
g/l
—
9
68
5
41
1.24
0.22
3.2
3.1
7.41
7.42
ph
—
5
36
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.9
—
8.54
—
0
11
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
2.3
—
—
—
0
0
6
50
1.22
0.20
2.0
1.9
—
0.00
estimate
—
0
11
18
157
1.20
0.20
1.3
1.5
—
—
—
0
0
55
532
1.24
0.14
5.2
5.3
6.07
6.07
mmol/l
0.01
50
490
11
94
1.21
0.14
1.4
1.2
—
—
—
0
0
22
204
1.12
0.10
3.7
3.5
—
—
—
0
0
23
240
0.93
0.04
2.0
2.3
—
—
—
0
0
21
203
1.05
0.01
4.4
4.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
52.43
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
149.53
—
0
5
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
106.00
—
0
5
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
7.12
—
0
5
0
9
0.00
-0.00
0.0
2.2
—
9.78
—
0
9
0
8
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
14.80
—
0
5
0
7
0.00
-0.00
0.0
4.6
—
0.87
—
0
7
6
59
1.02
-0.00
1.8
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
7.33
—
0
5
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint H7_IRIDOLENS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have H7_IRIDOLENS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

↥

Index endpoint: H7_IRIDOLENS – Lens-induced iridocyclitis

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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