No definition available.
Heart failure and hypertrophic cardiomyopathy
I9_HEARTFAIL_AND_HYPERTCARDIOM
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditions
|
1767 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
752 |
6. Filter based on genotype QC (FinnGen only) |
660 |
Control definitions (FinnGen only)
- Control conditions
- not I9_HYPERTROCARDMYOP
Extra metadata
- First used in FinnGen datafreeze
- DF5
Similar endpoints
↥List of similar endpoints to
Heart failure and hypertrophic cardiomyopathy
based on the number of shared cases.
Similar with more cases:
- Hypertrophic cardiomyopathy
- Cardiomyopathy
- Heart failure, strict
- Heart failure,strict
- Heart failure, not strict
Similar with less cases:
None
Case counts by codes
↥FinnGen case counts by registry codes:
No data for upset plot.
No data for upset table.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3880 | 1606 | 2239 |
| Only index persons | 3162 | 1299 | 1863 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.05 | 0.06 |
| Only index persons | 0.06 | 0.05 | 0.07 |
| Median age at first event (years) | |||
| Whole population | 64.57 | 67.92 | 62.15 |
| Only index persons | 64.98 | 68.74 | 62.35 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 660 | 246 | 414 |
| Unadjusted period prevalence (%) | 0.15 | 0.09 | 0.19 |
| Median age at first event (years) | 62.79 | 65.06 | 61.44 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 685
- Matched controls
- 6850
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I50.9
ICD-10 Finland
Heart failure, unspecified
27.1
307.7
549
887
I42.2
ICD-10 Finland
Other hypertrophic cardiomyopathy
10607.5
307.7
503
*
I42.9
ICD-10 Finland
Cardiomyopathy, unspecified
65.6
307.7
187
39
201
Kela drug reimbursment
Chronic cardiac insufficiency
21.5
307.7
321
270
I42.0
ICD-10 Finland
Dilated cardiomyopathy
47.7
307.7
282
99
I42.1
ICD-10 Finland
Obstructive hypertrophic cardiomyopathy
+∞
307.7
321
*
C03DA01
ATC
spironolactone; oral
14.5
289.5
408
630
I50.0
ICD-10 Finland
Congestive heart failure
13.6
254.5
320
415
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
13.6
239.7
287
345
I50.1
ICD-10 Finland
Left ventricular failure
14.9
233.8
251
256
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
14.3
228.6
252
267
C01BD01
ATC
amiodarone; systemic
22.2
220.9
177
106
C03CA01
ATC
furosemide; systemic
20.0
217.6
610
1982
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
8.9
186.2
417
1020
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
33.5
174.6
115
41
I47.2
ICD-10 Finland
Ventricular tachycardia
22.7
172.4
133
72
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
13.4
168.6
180
177
FJA10
NOMESCO Finland
Transvenous biopsy of right ventricle
84.0
165.2
88
12
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
8.1
163.1
456
1355
B01AA03
ATC
warfarin; systemic
7.6
158.3
416
1157
I48
ICD-10 Finland
Atrial fibrillation and flutter
7.4
150.2
448
1390
207
Kela drug reimbursment
Chronic arrhythmias
7.0
145.6
364
951
TFP20
NOMESCO Finland
Cardiodefibrillation
7.2
109.7
199
368
C07AB07
ATC
bisoprolol; oral
10.3
108.6
612
3066
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
24.7
106.2
77
35
XF404
NOMESCO Finland
Ambulatory ECG
6.8
106.1
205
403
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.4
104.1
316
934
GD1LA
NOMESCO Finland
GD
19.6
99.6
80
46
289
Kela drug reimbursment
Combination product containing sacubitril and valsartan
21.8
99.6
76
39
250, ,
Kela drug reimbursment
14.5
93.1
88
69
FPG32
NOMESCO Finland
Implantation of cardioverter-defibrillator with atrial and ventricular electrodes
35.8
92.8
59
18
C01AA05
ATC
digoxin; systemic
6.1
92.2
199
431
C09DX04
ATC
valsartan and sacubitril; oral
21.8
90.7
69
35
FPG30
NOMESCO Finland
Implantation of cardioverter-defibrillator with ventricular electrode
38.0
89.7
56
16
AN1
HP
Coronary angiography
5.3
86.9
231
599
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
6.9
86.5
154
275
381
Kela drug reimbursment
Combination product containing sacubitril and valsartan
20.5
85.8
67
36
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
4.2
75.5
347
1347
I44.2
ICD-10 Finland
Atrioventricular block, complete
8.7
75.4
103
136
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
4.2
72.9
289
1005
FPG96
NOMESCO Finland
Other implantation of permanent cardioverter-defibrillator
32.8
70.7
46
15
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
5.8
68.8
145
302
C09AA05
ATC
ramipril; oral
3.9
68.1
366
1556
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
4.2
67.9
262
887
127
Kela drug reimbursment
Transplant complication
16.7
66.4
57
37
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.5
65.3
527
2917
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
6.4
60.3
111
202
I50
ICD-10 Finland
Heart failure
7.4
58.9
92
141
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
11.3
57.8
63
61
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
6.6
56.3
98
168
L04AD02
ATC
tacrolimus; systemic
22.3
56.3
42
20
XF400
NOMESCO Finland
ECG with 12 standard connections
3.8
55.7
231
807
L04AA06
ATC
mycophenolic acid; systemic
12.6
55.6
56
48
M04AA01
ATC
allopurinol; systemic
3.9
55.0
215
721
B01AF02
ATC
apixaban; oral
3.8
54.5
220
753
FPE30
NOMESCO Finland
Replacement of transvenous cardiac pacemaker pulse generator
10.7
53.2
60
61
TK800
NOMESCO Finland
Hemodialysis
10.1
52.6
62
67
C07AA07
ATC
sotalol; systemic
6.4
51.1
92
163
PH1AC
NOMESCO Finland
Flebography of over extremity with X-ray
11.2
50.6
55
53
R06.0
ICD-10 Finland
Dyspnoea
3.2
49.6
323
1478
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
5.7
48.6
100
201
I11.0
ICD-10 Finland
Hypertensive heart disease with (congestive) heart failure
7.0
46.6
75
118
Z2221
NOMESCO Finland
Medical doctor
3.2
46.5
281
1221
Z94.1
ICD-10 Finland
Heart transplant status
91.8
46.5
51
6
XF640, ,
NOMESCO Finland
7.7
44.8
66
94
I48.2
ICD-10 Finland
Chronic atrial fibrillation
5.0
44.7
107
245
I49.0
ICD-10 Finland
Ventricular fibrillation and flutter
13.5
43.8
42
33
WX892
NOMESCO Finland
Monitored bed care
4.4
43.7
125
330
ZXD05
NOMESCO Finland
Urgent procedure
3.0
41.3
295
1391
Z3231
NOMESCO Finland
Registered nurse
3.0
41.1
288
1343
A10BK01
ATC
dapagliflozin; oral
4.3
41.0
122
331
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
3.8
39.9
141
433
I49.5
ICD-10 Finland
Sick sinus syndrome
5.3
39.2
86
182
ZX120
NOMESCO Finland
Intravenous
3.9
38.8
130
384
TPH04
NOMESCO Finland
Cathetrisation of vein
3.0
38.8
249
1100
K77
ICPC
Heart failure
6.8
38.7
63
100
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.5
38.6
163
562
FQA10
NOMESCO Finland
Orthotopic transplantation of heart with bicaval anastomosis
141.4
38.1
40
*
R4110
NOMESCO Finland
Physiotherapy
2.8
37.6
282
1351
G04BE03
ATC
sildenafil; oral
9.1
37.4
47
55
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
3.8
37.3
131
399
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.1
35.7
187
732
A12BA01
ATC
potassium chloride; oral
4.8
35.2
85
195
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
3.7
35.0
131
416
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.8
34.6
247
1144
I42
ICD-10 Finland
Cardiomyopathy
+∞
33.6
32
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.7
33.5
301
1561
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
4.5
33.3
88
217
K78
ICPC
Atrial fibrillation/flutter
3.5
33.0
132
437
WX872
NOMESCO Finland
Intensive care
4.5
32.8
87
215
81
HP
Angiography of the heart and coronary arteries
3.8
32.1
111
333
N17.9
ICD-10 Finland
Acute renal failure, unspecified
4.7
32.0
79
184
K84
ICPC
Heart disease other
5.8
31.7
61
114
TPH07
NOMESCO Finland
Cathetrisation of artery
3.2
31.5
148
540
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.6
31.0
117
372
WX740
NOMESCO Finland
Nitrogen oxide therapy
115.4
30.9
33
*
4251A
ICD-9 Finland
Cardiomyopathy, Hypertrophic obstructive cardiomyopathy
+∞
30.4
29
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.5
30.0
332
1875
XF402
NOMESCO Finland
ECG with work load test
3.2
29.8
140
510
FPH10
NOMESCO Finland
Open removal of transvenous cardiac pacemaker or cardioverter-defibrillator
59.5
29.4
34
6
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
4.5
29.3
76
184
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.5
28.7
277
1462
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
5.6
28.4
56
107
I42.8
ICD-10 Finland
Other cardiomyopathies
57.6
28.4
33
6
C07AG02
ATC
carvedilol; oral
3.8
28.2
95
279
I48.1
ICD-10 Finland
Persistent atrial fibrillation
4.2
27.8
79
205
ZXE00
NOMESCO Finland
One hour or less
2.4
27.6
325
1869
FPE00
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with ventricular electrode
5.6
27.4
54
103
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
6.5
27.4
46
75
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.8
27.2
89
256
XFE00
NOMESCO Finland
Epicardial ultrasonography
6.2
26.8
47
80
TFP30
NOMESCO Finland
Cathetric examination for cardiac arrythmia
25.2
25.9
36
15
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.9
25.9
149
605
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
4.6
25.9
64
149
FPG40
NOMESCO Finland
Replacement of pulse generator in transvenous cardioverter-defibrillator
97.2
25.8
28
*
A46
ICD-10 Finland
Erysipelas
2.7
24.7
165
722
1CX08, ,
NOMESCO Finland
39.1
24.1
30
8
TK810
NOMESCO Finland
Hemofiltration
23.8
24.1
34
15
AS4
HP
Physiological pacemaker insertion DDD (R)
7.5
23.9
35
49
Z3226
NOMESCO Finland
Physiotherapist
2.6
23.8
174
795
TFJ02
NOMESCO Finland
Muscle biopsy of heart
43.1
23.8
29
7
R02
ICPC
Shortness of breath/dyspnoea
2.7
23.7
149
632
M10.9
ICD-10 Finland
Gout, unspecified
3.2
23.6
103
356
I46.0
ICD-10 Finland
Cardiac arrest with successful resuscitation
7.1
23.6
36
53
TFP34
NOMESCO Finland
Electrophysiological investigation
5.3
23.1
48
96
R55
ICD-10 Finland
Syncope and collapse
2.8
22.6
136
563
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
5.8
22.5
42
76
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
46.7
22.5
27
6
N18.8
ICD-10 Finland
Other chronic renal failure
5.7
22.4
43
80
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.1
22.0
63
164
ZXE10
NOMESCO Finland
More than one and less than three hours
2.2
22.0
302
1806
C07AB02
ATC
metoprolol; systemic
2.3
21.9
214
1111
ZXE40
NOMESCO Finland
More than seven and less than nine hours
6.2
21.9
38
64
TFP35
NOMESCO Finland
Electroanatomical mapping
7.7
21.8
31
42
7AX01, ,
NOMESCO Finland
226.9
21.7
22
*
I43.1*E85.9
ICD-10 Finland
Cardiac amyloidosis
+∞
20.9
20
*
TFP00
NOMESCO Finland
Temporary use of transvenous or epicardial pacemaker
7.7
20.5
29
39
H02AB06
ATC
prednisolone; systemic
2.1
20.4
383
2562
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
5.5
20.4
40
76
AP4
HP
Myocardial biopsy
33.7
20.3
26
8
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
6.3
20.0
34
56
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.6
19.8
68
201
I45.9
ICD-10 Finland
Conduction disorder, unspecified
8.4
19.7
26
32
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
2.1
19.5
268
1585
A10BK03
ATC
empagliflozin; oral
2.7
19.4
122
513
AA1AD
NOMESCO Finland
CT of head and brain
2.1
19.4
282
1704
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.7
18.6
61
175
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
4.0
18.5
55
147
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.1
18.4
84
297
TFC25
NOMESCO Finland
Transseptal catheterisation of left atrium or ventricle
8.1
18.4
25
32
3AC01, ,
NOMESCO Finland
20.0
18.3
27
14
AP1
HP
Catheterization of the left side of the heart
5.9
18.2
33
58
Z2446
NOMESCO Finland
Social worker
3.3
18.0
73
240
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.1
18.0
79
273
FXL00
NOMESCO Finland
Insertion and use of extra-, para- or intracorporeal VAD
184.6
17.6
18
*
3A064, ,
NOMESCO Finland
29.7
17.5
23
8
C01DA14
ATC
isosorbide mononitrate; oral
2.2
17.4
186
989
ZX108
NOMESCO Finland
Inhalation
14.4
17.4
29
21
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
4.0
17.4
51
135
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.5
17.4
128
580
H03BB01
ATC
carbimazole; oral
4.6
17.3
42
96
D64.9
ICD-10 Finland
Anaemia, unspecified
2.5
17.3
124
555
R07.4
ICD-10 Finland
Chest pain, unspecified
2.1
17.2
252
1512
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
16.9
214
1215
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.0
16.8
82
301
A11CC03
ATC
alfacalcidol; systemic
5.0
16.8
37
78
Z49.1
ICD-10 Finland
Extracorporeal dialysis
7.2
16.6
25
36
AS8
HP
Physiological arrhythmia pacemaker insertionDDD (R) S
28.3
16.6
22
8
205
Kela drug reimbursment
Chronic hypertension
2.0
16.6
261
1603
B01AB05
ATC
enoxaparin; parenteral
2.0
16.5
267
1655
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.2
16.3
69
233
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
7.0
16.2
25
37
I47.1
ICD-10 Finland
Supraventricular tachycardia
3.8
16.2
51
142
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.7
15.8
52
149
71
HP
Electrophysiological Special Examination
16.2
15.8
25
16
FPJ24
NOMESCO Finland
Revision of biventricular cardioverter-defibrillator with atrial and ventricular electrodes
34.3
15.8
20
6
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
13.3
15.8
27
21
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
5.8
15.7
29
52
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.6
15.5
53
156
ZXE20
NOMESCO Finland
More than three and less than five hours
2.3
15.5
132
636
A10BH05
ATC
linagliptin; oral
3.0
15.5
71
251
XF600
NOMESCO Finland
Bloodpressure measurement
3.0
15.5
71
251
4273A
ICD-9 Finland
Cardiac dysrhythmias, Atrial fibrillation and flutter
5.4
15.5
31
60
C10AA01
ATC
simvastatin; oral
1.9
15.4
378
2679
AP3
HP
Catheterization of the right and left side of the heart
29.4
15.3
20
7
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
5.8
15.2
28
50
AP2
HP
Catheterization of the right side of the heart
24.0
15.2
21
9
742, ,
NOMESCO Finland
46.1
15.1
18
*
AS7
HP
Arrhythmia pacemaker insertion VVI (R) S
46.1
15.1
18
*
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
3.6
15.1
52
154
PD5BD
NOMESCO Finland
Extensive CT of aorta
5.6
15.1
29
54
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.9
14.8
75
281
FPE37
NOMESCO Finland
Implantation of biventricular cardioverter-defibrillator with atrial and ventricular electrodes
21.6
14.7
21
10
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
3.6
14.7
50
147
N17.8
ICD-10 Finland
Other acute renal failure
6.5
14.6
24
38
AK1
HP
HTX (heart transplant)
+∞
14.6
14
*
M10
ICD-10 Finland
Gout
3.3
14.6
56
178
L04AD01
ATC
ciclosporin; systemic
6.0
14.6
26
45
TKC20
NOMESCO Finland
Catheterisation of bladder
2.7
14.4
82
326
73
HP
Initial pacemaker installation
13.8
14.3
24
18
C08DA01
ATC
verapamil; systemic
3.3
14.2
56
181
TFP47
NOMESCO Finland
Ablation or modification of the AV-node
12.3
14.2
25
21
103
Kela drug reimbursment
Diabetes, insulin-treated
1.9
14.1
248
1562
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.5
14.1
50
151
N19
ICD-10 Finland
Unspecified kidney failure
3.3
14.0
55
177
C01BA03
ATC
disopyramide; systemic
11.7
13.9
25
22
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
5.9
13.8
25
44
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.8
13.7
42
115
WX002
NOMESCO Finland
Sedation and analgesia
2.1
13.6
164
904
ARB
HP
Catheter ablation of arrhythmia: Cutiing or modification of the AV node
76.7
13.6
15
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
13.5
239
1506
FPJ22
NOMESCO Finland
Revision of cardioverter-defibrillator with atrial and ventricular electrodes
26.3
13.4
18
7
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
2.0
13.4
192
1126
A10AB05
ATC
insulin aspart; parenteral
2.6
13.3
81
333
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.1
13.2
153
830
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
40.9
13.2
16
*
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
5.6
13.1
25
46
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.0
13.1
161
894
C03AA03
ATC
hydrochlorothiazide; oral
2.4
13.0
93
413
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
2.4
13.0
103
479
ATX
HP
Other pacemaker replacement or related action, such as cord removal or replacement
29.0
13.0
17
6
I44.7
ICD-10 Finland
Left bundle-branch block, unspecified
5.0
12.9
28
58
I42.5
ICD-10 Finland
Other restrictive cardiomyopathy
51.0
12.9
15
*
I25.5
ICD-10 Finland
Ischaemic cardiomyopathy
4.4
12.8
32
75
I20.00
ICD-10 Finland
Unstable angina
3.5
12.7
44
131
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.9
12.7
227
1430
L28
ICPC
Limited function/disability (L)
2.0
12.6
179
1043
E05.89
ICD-10 Finland
Other thyrotoxicosis
32.7
12.6
16
5
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.4
12.5
46
142
R03BB04
ATC
tiotropium bromide; inhalant
2.3
12.5
106
507
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.3
12.5
103
487
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
3.0
12.5
59
212
I47.9
ICD-10 Finland
Paroxysmal tachycardia, unspecified
5.9
12.3
22
38
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.3
12.3
97
450
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
2.2
12.2
113
561
R00.1
ICD-10 Finland
Bradycardia, unspecified
3.3
12.2
48
155
FPE40
NOMESCO Finland
Replacement of transvenous cardiac pacemaker electrode
12.7
12.2
21
17
E66.8
ICD-10 Finland
Other obesity
3.6
12.1
40
115
I41.8*D86.8
ICD-10 Finland
Sarcoid myocarditis
27.2
12.1
16
6
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.9
12.0
59
217
FM1DM
NOMESCO Finland
Heart very extensive MRI examination with 3 Tesla magnet
47.5
11.9
14
*
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.3
11.8
103
499
B01AE07
ATC
dabigatran etexilate; oral
3.3
11.7
44
138
C09AA02
ATC
enalapril; systemic
1.9
11.7
178
1060
R04.0
ICD-10 Finland
Epistaxis
2.5
11.6
80
349
R18
ICD-10 Finland
Ascites
4.4
11.6
29
68
42500
ICD-8 Finland
Cardiomyopathy, Stenosis subaortae hypertrophicans
+∞
11.5
11
*
FPE96
NOMESCO Finland
Other implantation or replacement of transvenous cardiac pacemaker
9.8
11.3
22
23
E85.9
ICD-10 Finland
Amyloidosis, unspecified
35.7
11.3
14
*
XF622
NOMESCO Finland
Measurement of minute volume of heart
35.7
11.3
14
*
J94.8
ICD-10 Finland
Other specified pleural conditions
5.0
11.3
24
49
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
3.9
11.1
33
88
I25.2
ICD-10 Finland
Old myocardial infarction
2.4
11.1
81
362
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
11.0
266
1819
ASB
HP
Insertion of a biventricular physiological pacemaker DDD (R)
44.1
10.9
13
*
PA2VT
NOMESCO Finland
Intravascular evacuation of brain artery embolus
10.8
10.8
20
19
TFP32
NOMESCO Finland
Cathetric treatmen of cardiac arrythmia
18.2
10.8
16
9
J01CA04
ATC
amoxicillin; systemic
1.9
10.7
536
4485
5AB14, ,
NOMESCO Finland
61.0
10.7
12
*
AQ1
HP
Conventional electrophysiological examination
10.3
10.6
20
20
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.9
10.5
51
186
FXM00
NOMESCO Finland
Removal of extra-, para- or intracorporeal VAD
111.7
10.4
11
*
ZX197, ,
NOMESCO Finland
+∞
10.4
10
*
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.5
10.4
70
302
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
3.2
10.4
42
138
L04AX01
ATC
azathioprine; systemic
3.3
10.3
39
123
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.1
10.3
115
613
C09AA04
ATC
perindopril; oral
2.7
10.2
55
213
FP4B5
NOMESCO Finland
ECG, prolonged recording (24 h)
4.7
10.1
23
50
R4190
NOMESCO Finland
Nutritional therapy
3.3
10.0
38
120
XFP02, ,
NOMESCO Finland
40.7
10.0
12
*
2BD01, ,
NOMESCO Finland
40.7
10.0
12
*
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
3.8
10.0
30
81
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.8
9.9
219
1450
D86.0
ICD-10 Finland
Sarcoidosis of lung
5.3
9.9
20
39
R53
ICD-10 Finland
Malaise and fatigue
1.8
9.8
194
1243
UJF92
NOMESCO Finland
Capsular endoscopy
4.6
9.8
23
51
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
3.1
9.8
42
143
TK830
NOMESCO Finland
Ultrafiltration
55.8
9.7
11
*
B01AB04
ATC
dalteparin; parenteral
2.8
9.5
47
173
Z95.8
ICD-10 Finland
Presence of other cardiac and vascular implants and grafts
15.3
9.5
15
10
JN3AD
NOMESCO Finland
Abdominal CT examination
2.0
9.5
108
578
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.7
9.5
268
1894
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
2.9
9.5
46
168
WX882
NOMESCO Finland
High dependency care
3.5
9.4
32
94
B03XA02
ATC
darbepoetin alfa; parenteral
3.8
9.4
28
75
FN2EG
NOMESCO Finland
Catheter-based alcohol septal ablation
+∞
9.4
9
*
WX722
NOMESCO Finland
PEEP
2.7
9.4
52
204
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.7
9.4
205
1351
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.1
9.3
40
136
C08CA02
ATC
felodipine; oral
2.1
9.1
92
471
J01FF01
ATC
clindamycin; systemic
1.7
9.1
195
1277
TFP52
NOMESCO Finland
Ablation treatment of ventricular tachycardia due to structural heart defect
37.2
9.0
11
*
63
HP
Cardiac muscle biopsy
37.2
9.0
11
*
FPH00
NOMESCO Finland
Transvenous extraction of transvenous cardiac pacemaker or cardioverter-defibrillator
37.2
9.0
11
*
A41.9
ICD-10 Finland
Sepsis, unspecified
2.9
9.0
42
150
C08DB01
ATC
diltiazem; oral
2.5
9.0
55
227
74
HP
Initial installation of the atrial pacemaker
18.9
9.0
13
7
4254A
ICD-9 Finland
Cardiomyopathy, Other primary cardiomyopathies
24.4
8.9
12
5
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.1
8.8
36
119
E87.5
ICD-10 Finland
Hyperkalaemia
3.8
8.8
27
74
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.0
8.8
102
550
A10BB12
ATC
glimepiride; oral
2.2
8.8
73
346
KA1AE
NOMESCO Finland
Kidney ultrasound examination
3.5
8.7
30
89
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
6.7
8.7
21
32
I21.99
ICD-10 Finland
Myocardial infarction (acute) UNS unspecified coronary artery status
3.1
8.7
36
120
XF614
NOMESCO Finland
Measurement of pulmonary artery pressure
50.6
8.7
10
*
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.6
8.7
50
200
J01MA12
ATC
levofloxacin; systemic
1.8
8.7
154
953
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
3.7
8.6
27
75
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
2.3
8.6
67
308
C01BB02
ATC
mexiletine; systemic
16.5
8.6
13
8
M01AE01
ATC
ibuprofen; systemic, rectal
0.6
8.5
439
5112
N05CF01
ATC
zopiclone; oral
1.7
8.5
241
1695
I42.4
ICD-10 Finland
Endocardial fibroelastosis
91.1
8.4
9
*
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
91.1
8.4
9
*
A02BC02
ATC
pantoprazole; systemic
1.7
8.4
475
3948
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.8
8.4
42
156
J45.9
ICD-10 Finland
Asthma, unspecified
1.8
8.4
140
849
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
3.0
8.4
36
123
FPH20
NOMESCO Finland
Removal of epicardial pacemaker or cardioverter-defibrillator
+∞
8.3
8
*
FQA00
NOMESCO Finland
Orthotopic transplantation of heart
+∞
8.3
8
*
T86.2
ICD-10 Finland
Heart transplant failure and rejection
+∞
8.3
8
*
FJA00
NOMESCO Finland
Biopsy of right ventricle
+∞
8.3
8
*
I44.1
ICD-10 Finland
Atrioventricular block, second degree
3.4
8.3
29
87
I20.09
ICD-10 Finland
Unstable angina
2.3
8.3
61
274
N05BA01
ATC
diazepam; systemic, rectal
2.0
8.3
100
546
S97
ICPC
Chronic ulcer skin
2.3
8.3
67
314
J01DB01
ATC
cefalexin; oral
1.8
8.2
546
4726
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.1
8.1
84
433
JN4AD
NOMESCO Finland
Body CT examination
1.9
8.1
106
594
FPH96
NOMESCO Finland
Other removal of cardiac pacemaker or cardioverter-defibrillator
11.9
8.1
14
12
WX730
NOMESCO Finland
Conventional respirator
4.5
7.9
19
43
M01AH05
ATC
etoricoxib; oral
0.6
7.9
234
3124
A10BA02
ATC
metformin; oral
1.6
7.9
234
1656
61
HP
Catheterization and pressure measurement of the left side of the heart
3.6
7.9
26
75
A10AE04
ATC
insulin glargine; parenteral
2.0
7.9
87
460
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
2.9
7.9
37
133
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
1.9
7.9
103
578
I20.9
ICD-10 Finland
Angina pectoris, unspecified
4.1
7.8
21
52
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.2
7.8
71
349
N02AX02
ATC
tramadol; systemic, rectal
1.6
7.7
311
2365
FPG04
NOMESCO Finland
Insertion of internal defibrillator, atrial and chamber electrode
45.5
7.7
9
*
FXD00
NOMESCO Finland
Use of ECHLA without concurrent surgical procedure
45.5
7.7
9
*
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
2.4
7.7
56
250
ZXA05
NOMESCO Finland
Left side
1.7
7.7
190
1283
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
7.5
7.7
17
23
WW200
NOMESCO Finland
Immunization
3.5
7.6
26
77
A28
ICPC
Limited function/disability NOS
1.7
7.6
166
1086
FPG42
NOMESCO Finland
Replacement of electrode(s) in transvenous cardioverter-defibrillator
80.9
7.4
8
*
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
3.8
7.4
22
59
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.6
7.4
44
179
A06AD11
ATC
lactulose; oral
1.8
7.4
127
776
R4120
NOMESCO Finland
Occupational therapy
2.4
7.4
53
236
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
7.3
157
1020
FXE00
NOMESCO Finland
Use of ECLA
+∞
7.3
7
*
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.4
7.3
51
224
WX402
NOMESCO Finland
General anaesthesia
1.7
7.3
144
915
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
7.2
117
702
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.0
7.2
31
106
UJF32
NOMESCO Finland
Coloscopy
1.6
7.2
198
1373
EBA10
NOMESCO Finland
Operative extraction of tooth
2.1
7.1
68
340
E66.00
ICD-10 Finland
Metabolic syndrome
2.4
7.1
47
201
FPJ00
NOMESCO Finland
Revision of pacemaker pulse generator or electrode
12.2
7.1
12
10
TFN04, ,
NOMESCO Finland
12.2
7.1
12
10
D75.1
ICD-10 Finland
Secondary polycythaemia
10.2
7.1
13
13
R2110
NOMESCO Finland
Giving the first information
2.6
7.0
41
166
I49.3
ICD-10 Finland
Ventricular premature depolarization
2.2
6.9
59
282
A12AA04
ATC
calcium carbonate; oral
4.0
6.9
19
48
I20.99
ICD-10 Finland
Angina pectoris, unspecified
2.1
6.9
67
337
C01BA01
ATC
quinidine; oral
6.8
6.8
16
24
FN1CD
NOMESCO Finland
Very extensive CT of coronary arteries
11.1
6.8
12
11
R1410
NOMESCO Finland
Drawing up a rehabilitation plan
11.1
6.8
12
11
FM1LE
NOMESCO Finland
Combined ultrasound and EKG examination of heart with tolerance test
9.4
6.8
13
14
FXF00
NOMESCO Finland
Decannulation after ECHLA or ECLA
40.5
6.8
8
*
E85.4
ICD-10 Finland
Organ-limited amyloidosis
40.5
6.8
8
*
G47.3
ICD-10 Finland
Sleep apnoea
1.6
6.7
166
1116
FPE36
NOMESCO Finland
Implantation of biventricular cardioverter-defibrillator with ventricular electrodes
22.8
6.7
9
*
I24.0
ICD-10 Finland
Coronary thrombosis not resulting in myocardial infarction
22.8
6.7
9
*
ZYB02
NOMESCO Finland
Outreach service at unit of another specialty
22.8
6.7
9
*
AS6
HP
Biventricular physiological heart failure pacemaker insertion DDD (R)
22.8
6.7
9
*
R50.9
ICD-10 Finland
Fever, unspecified
1.8
6.7
113
686
TFP46
NOMESCO Finland
Ablation treatment of atrial fibrillation
4.1
6.7
18
45
RS221, ,
NOMESCO Finland
5.6
6.6
18
33
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
6.6
258
1931
Z95.9
ICD-10 Finland
Presence of cardiac and vascular implant and graft, unspecified
12.4
6.6
11
9
J01MA14
ATC
moxifloxacin; systemic
2.0
6.6
72
379
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
2.9
6.6
31
112
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
3.1
6.5
26
85
NH1AD
NOMESCO Finland
Ankle and foot CT
3.7
6.5
20
55
TFC10
NOMESCO Finland
Catheterisation of left atrium or ventricle
3.6
6.5
21
60
R04.2
ICD-10 Finland
Haemoptysis
2.6
6.5
38
154
3A149, ,
NOMESCO Finland
70.5
6.4
7
*
I41.8
ICD-10 Finland
Myocarditis in other diseases classified elsewhere
70.5
6.4
7
*
AT7
HP
Replacing the pacemaker VVI (R) S
70.5
6.4
7
*
120, ,
NOMESCO Finland
70.5
6.4
7
*
GD1AD
NOMESCO Finland
Thorax CT examination
2.1
6.4
58
284
AQ2
HP
Electrophysiological electroanatomical examination
14.5
6.4
10
7
FM1CD
NOMESCO Finland
Very extensive CT of heart
14.5
6.4
10
7
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
3.1
6.4
26
86
A08
ICPC
Swelling
2.2
6.4
53
251
J45.1
ICD-10 Finland
Nonallergic asthma
2.2
6.4
53
251
K99
ICPC
Cardiovascular disease other
3.0
6.4
28
97
I31.9
ICD-10 Finland
Disease of pericardium, unspecified
6.6
6.4
15
23
L04AA01
ATC
[U] ciclosporin
6.6
6.4
15
23
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.6
6.3
177
1226
ZXD00
NOMESCO Finland
Emergency procedure
3.3
6.3
23
71
K29
ICPC
Cardiovascular sympt/complt other
2.5
6.3
40
168
K90
ICPC
Stroke/cerebrovascular accident
2.7
6.3
33
126
C10AA03
ATC
pravastatin; oral
2.0
6.3
66
342
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
6.3
173
1193
J96.1
ICD-10 Finland
Chronic respiratory failure
3.1
6.3
26
87
C08CA05
ATC
nifedipine; systemic
2.2
6.3
52
246
AT8
HP
Physiological pacemaker replacement DDD (R) S
+∞
6.3
6
*
4259X
ICD-9 Finland
Cardiomyopathy, Secondary cardiomyopathy, unspecified
26.9
6.2
8
*
W19
ICD-10 Finland
Unspecified fall
1.9
6.2
77
423
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
6.2
278
2137
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
5.8
6.2
16
28
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
2.8
6.2
31
116
R60.0
ICD-10 Finland
Localized oedema
1.8
6.2
97
576
A10AC01
ATC
insulin (human); parenteral
2.0
6.1
63
326
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.3
6.0
47
217
Z51.5
ICD-10 Finland
Palliative care
1.8
6.0
85
488
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
536
2327
6.99
113.58
13.6
3.3
3738.64
1569.09
ng/l
12.47
524
2016
342
1035
5.60
110.70
4.9
2.6
20.75
22.57
%
1.97
331
964
247
566
6.26
109.36
7.6
3.3
508.29
231.89
ng/l
6.40
242
515
365
1192
5.41
107.18
4.9
2.6
12.13
12.60
umol/l
0.67
350
1108
350
1112
5.39
106.05
4.9
2.6
2.31
2.26
g/l
1.02
333
1025
245
671
5.13
86.28
26.6
7.2
13.23
10.49
mmol/l
5.00
236
644
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
139
248
6.78
77.77
5.1
2.8
0.36
0.36
iu/ml
0.05
75
135
132
271
5.79
63.32
4.8
3.5
3.95
4.35
pmol/l
4.00
123
237
200
613
4.20
58.45
5.2
2.6
25.35
7.73
ug/l
3.93
187
550
257
968
3.65
55.25
11.5
5.9
1.12
1.03
mmol/l
5.02
238
903
284
1143
3.54
55.01
12.3
3.3
0.83
0.82
mmol/l
0.79
272
1076
194
633
3.88
51.24
3.0
3.1
64.23
66.22
g/l
2.82
184
580
200
671
3.80
50.66
18.9
7.7
1.55
1.40
mmol/l
0.91
193
659
98
193
5.76
48.67
2.9
3.3
0.83
0.86
nmol/l
0.20
73
161
529
3271
3.71
48.00
52.2
17.7
1.76
1.32
inr
37.01
472
2745
94
185
5.73
46.66
5.2
2.8
3.61
3.62
g/l
0.01
83
176
351
1740
3.09
46.01
4.0
2.4
3.45
3.01
mg/l
1.59
319
1486
259
1119
3.11
42.66
6.7
2.1
32.86
29.63
s
10.08
254
1092
201
751
3.37
42.26
7.4
3.8
1.73
1.86
mmol/l
0.19
182
640
217
854
3.26
41.83
11.0
4.3
265.52
245.63
u/l
1.36
206
808
286
1320
3.00
41.70
10.8
4.2
599.18
336.48
ng/l
0.51
281
1126
443
2596
3.00
41.27
5.7
3.0
171.62
163.12
ug/l
0.31
424
2377
57
78
7.88
39.99
1.5
1.2
4.60
6.38
u/ml
0.27
30
39
202
780
3.25
39.98
7.4
3.7
5.91
5.80
kpa
0.70
197
755
53
67
8.49
39.71
1.4
1.1
—
—
—
0
0
107
269
4.53
39.69
5.0
2.1
2094.36
606.07
ug/l
0.50
102
256
55
74
7.99
39.13
1.5
1.3
1.24
3.46
u/ml
0.96
21
28
66
122
5.88
34.79
1.8
1.5
25.27
31.04
g/l
2.68
56
109
204
880
2.88
32.37
17.9
7.7
11.19
11.82
kpa
1.23
197
852
204
880
2.88
32.37
17.9
7.7
4.97
5.10
kpa
0.84
195
850
114
350
3.71
31.87
1.9
1.9
1.50
1.54
g/l
0.13
98
322
66
133
5.38
31.66
12.1
6.4
625.83
268.05
iu/ml
0.56
18
20
201
870
2.85
31.59
17.8
7.8
0.27
0.96
mmol/l
1.48
165
720
254
1249
2.64
30.99
2.5
1.9
—
—
—
0
0
82
207
4.36
30.00
3.1
3.0
0.00
0.00
g/l
-0.00
76
192
199
882
2.77
29.67
2.6
1.9
—
—
—
0
0
78
192
4.46
29.46
1.8
1.6
—
—
—
0
0
55
100
5.89
29.42
1.5
1.4
151.53
166.20
au/ml
0.35
17
27
95
273
3.88
29.13
4.4
4.1
47.04
59.93
mg/l
0.38
85
235
95
273
3.88
29.13
4.4
4.1
55.90
79.57
mg/l
0.49
86
233
491
3355
2.64
28.84
18.2
7.6
1.19
1.21
mmol/l
8.19
439
2892
86
232
4.10
28.78
3.1
2.9
0.03
0.02
g/l
0.14
79
206
136
498
3.16
28.59
23.9
9.6
1.32
1.34
%
0.07
136
493
163
663
2.91
28.45
7.0
3.0
4.26
4.43
kpa
0.38
158
642
416
2645
2.46
28.37
10.3
4.3
72.99
56.85
ng/l
0.42
378
2109
84
226
4.10
28.20
3.1
2.9
0.00
0.00
g/l
-0.00
76
193
30
28
11.16
27.94
1.4
1.1
—
—
—
0
0
294
1611
2.45
27.87
8.8
4.4
64.58
85.43
%
27.12
285
1584
457
3046
2.50
27.86
19.1
6.9
1.19
1.21
mmol/l
8.40
441
2796
51
91
5.97
27.79
1.8
1.4
11388.68
110433.70
e6/l
0.77
34
50
92
268
3.81
27.62
3.3
2.9
0.73
1.43
g/l
0.89
83
232
40
56
7.52
27.40
1.1
1.1
—
—
—
0
0
38
51
7.83
26.98
2.3
2.3
17.63
20.34
iu/ml
—
6
7
202
941
2.63
26.95
2.5
1.9
—
—
—
0
0
94
284
3.68
26.73
3.0
2.7
3.20
2.99
g/l
1.14
88
256
346
2075
2.35
26.28
4.4
2.2
305.14
247.07
u/l
0.24
332
1968
89
263
3.74
26.13
3.0
2.7
10.28
10.70
g/l
0.34
81
233
97
304
3.55
26.08
3.0
2.6
3.66
3.69
g/l
0.08
91
276
97
304
3.55
26.08
3.0
2.6
4.00
4.13
g/l
0.83
90
276
97
304
3.55
26.08
3.0
2.6
7.35
7.36
g/l
0.01
90
276
53
105
5.39
25.83
1.8
1.4
726.34
1789.10
e6/l
2.27
41
69
442
2969
2.38
25.43
7.7
5.3
33.63
35.00
g/l
5.47
423
2766
485
3396
2.47
25.33
14.9
7.0
15.43
12.25
umol/l
7.77
472
3246
169
748
2.67
24.77
2.9
3.0
10.30
9.05
umol/l
0.50
152
668
85
253
3.69
24.65
4.6
3.7
9.78
4.04
ratio
0.30
54
146
66
166
4.29
24.16
4.0
2.2
11.06
13.12
mg/l
0.92
59
150
155
670
2.70
23.71
2.5
2.4
0.18
0.21
g/l
3.04
144
622
487
3468
2.40
23.65
16.1
9.7
4.83
4.24
e9/l
5.71
434
3019
104
364
3.19
23.35
2.0
1.5
—
—
—
0
0
131
526
2.84
23.05
6.4
4.0
123.32
91.82
ng/l
2.89
124
459
52
112
4.94
23.03
1.6
1.2
336.42
278.71
u/ml
0.51
45
58
243
1322
2.30
22.38
8.4
1.7
1.77
1.50
mg/l
0.48
196
1052
121
476
2.87
22.06
2.1
1.7
—
—
—
0
0
350
2219
2.18
21.96
5.0
3.7
75.03
107.02
e6/l
0.38
295
1740
291
1721
2.20
21.72
4.2
2.9
417.67
361.66
umol/l
10.86
258
1486
313
1917
2.17
21.25
4.9
3.5
0.77
0.50
e6/l
0.63
255
1452
127
523
2.75
21.19
1.8
1.7
—
—
—
0
0
64
176
3.91
20.73
3.2
3.2
32.22
33.40
umol/l
0.15
58
156
82
267
3.35
20.64
3.6
2.2
36.75
40.01
u/l
0.47
65
236
509
3797
2.33
20.59
15.8
5.5
7.18
6.85
mmol/l
2.03
493
3640
368
2442
2.10
19.79
5.9
4.3
49.81
138.49
e6/l
1.86
299
1793
268
1580
2.14
19.72
3.5
2.8
4.59
4.33
e6/l
0.15
254
1441
316
1991
2.09
19.43
3.8
3.5
56.98
34.69
u/l
1.22
301
1866
264
1557
2.13
19.32
4.0
2.5
—
—
—
0
0
57
154
3.95
18.90
1.7
1.5
—
—
—
0
0
387
2660
2.05
18.41
24.4
12.6
0.00
0.00
e9/l
0.28
323
2188
60
172
3.73
18.29
8.4
3.5
4.08
1.88
index
0.67
38
106
63
191
3.53
17.67
1.7
1.4
—
—
—
0
0
100
423
2.60
15.59
5.1
3.9
1.62
1.90
mmol/l
0.36
75
327
125
591
2.36
15.33
2.6
2.6
33.10
34.22
u/l
0.15
108
493
67
232
3.09
15.16
1.3
1.3
—
—
—
0
0
77
290
2.86
15.01
2.1
2.9
—
—
—
0
0
205
1194
2.02
14.79
4.3
3.2
0.94
1.04
e6/l
0.18
122
677
53
163
3.44
14.53
1.3
1.3
—
—
—
0
0
506
4008
2.00
14.14
6.8
5.2
84.09
2974.46
e6/l
2.14
11
72
191
1105
2.01
13.93
4.4
3.5
2.66
1.64
e6/l
0.84
106
586
61
215
3.02
13.37
5.5
3.2
2.04
1.64
mg/l
2.55
55
188
29
61
4.92
13.18
1.5
1.4
15.28
13.29
u/l
0.76
29
55
45
133
3.55
13.10
1.7
1.3
—
—
—
0
0
45
133
3.55
13.10
1.7
1.3
—
—
—
0
0
104
496
2.29
12.37
3.5
3.0
41.69
60.95
ml/min/173m2
6.73
59
222
294
2026
1.79
12.12
3.6
2.7
56.16
102.95
u/l
0.62
280
1878
41
121
3.54
11.97
1.6
1.8
—
—
—
0
0
554
4636
2.02
11.81
18.3
8.8
85.53
81.16
u/l
0.89
540
4375
28
64
4.52
11.54
12.1
3.2
12.82
12.68
index
0.03
22
47
102
501
2.22
11.27
2.3
2.7
10.36
11.03
g/l
0.70
95
453
46
153
3.15
11.13
4.8
2.5
15.84
16.14
%
0.24
46
148
53
193
2.89
10.97
1.6
1.6
—
—
—
0
0
32
87
3.81
10.53
1.6
1.6
—
—
—
0
0
49
181
2.84
9.89
1.6
1.6
—
—
—
0
0
22
47
4.80
9.83
13.5
3.2
1.14
0.91
index
0.64
22
47
50
188
2.79
9.76
1.7
1.4
1.19
1.18
g/l
0.08
45
180
33
100
3.42
9.28
1.3
1.4
—
—
—
0
0
36
117
3.19
9.07
2.6
1.8
1.53
1.63
mmol/l
0.37
36
111
170
1072
1.78
9.01
1.7
1.4
2.80
2.74
g/l
0.12
115
616
39
137
2.96
8.62
1.3
1.2
54.31
38.71
u/l
0.17
32
117
366
2845
1.62
8.61
4.5
2.9
—
—
estimate
—
0
0
47
185
2.65
8.42
1.7
1.4
0.24
0.23
g/l
0.29
40
177
30
93
3.33
8.16
1.8
1.6
—
—
—
0
0
46
183
2.62
8.08
4.0
2.2
124.59
129.10
g/l
0.55
37
147
500
4247
1.66
7.77
6.2
4.0
15.82
15.07
pmol/l
6.23
475
3810
25
71
3.62
7.76
2.0
2.7
923.88
1094.08
mg
0.18
25
71
28
87
3.31
7.60
3.2
3.6
—
—
—
0
0
15
17
8.99
7.57
1.1
1.1
188.47
239.62
iu/ml
0.26
15
17
119
714
1.81
7.34
5.1
3.6
—
—
—
0
0
68
339
2.12
7.19
2.3
1.9
2.61
2.37
ug/l
0.07
63
299
16
23
7.10
7.03
1.5
2.4
0.62
0.60
mmol/l
0.29
16
23
17
27
6.43
6.97
6.9
2.3
793.88
852.81
u/ml
0.10
17
27
18
44
4.17
6.85
1.3
1.2
—
—
—
0
0
293
2242
1.54
6.85
4.7
3.6
2.34
2.35
mmol/l
0.77
260
2016
18
45
4.08
6.66
1.3
1.2
—
—
—
0
0
268
2024
1.53
6.59
2.2
1.8
19.76
19.99
nmol/l
0.09
237
1697
298
2307
1.52
6.50
3.9
3.5
6.98
7.60
mmol/l
1.85
259
1924
44
191
2.39
6.48
1.3
1.5
—
—
—
0
0
18
46
3.99
6.47
1.3
1.2
—
—
—
0
0
18
46
3.99
6.47
1.3
1.2
—
—
—
0
0
56
271
2.16
6.40
6.8
4.0
1.42
1.38
mmol/l
0.13
56
266
297
2311
1.50
6.25
4.6
4.2
25.12
8.90
mg/mmol
3.10
234
1483
15
24
6.36
6.19
2.7
2.1
4592.50
83386.08
e6/l
—
8
13
16
29
5.62
6.02
3.2
2.6
522.00
1000.74
e6/l
0.49
11
23
74
407
1.92
5.98
8.3
3.9
45.61
47.82
%
0.35
74
397
12
15
8.12
5.85
1.0
1.0
—
—
—
0
0
362
2959
1.47
5.82
2.5
2.2
92.19
94.73
pmol/l
0.51
206
1575
19
55
3.52
5.77
1.3
1.2
—
—
—
0
0
22
72
3.12
5.54
1.5
2.0
—
—
—
0
0
499
4373
1.52
5.50
7.6
4.5
16.83
13.51
mm/h
3.67
479
4038
18
52
3.53
5.48
1.3
1.2
—
—
—
0
0
47
232
2.10
5.14
1.7
1.9
3.03
9.40
iu/ml
—
7
61
15
40
3.81
5.11
1.1
1.5
—
—
—
0
0
15
40
3.81
5.11
1.1
1.5
—
—
—
0
0
22
76
2.96
5.07
1.5
1.9
—
—
—
0
0
29
123
2.42
4.54
4.9
3.0
9.90
9.79
pmol/l
0.02
29
123
28
117
2.45
4.53
1.7
1.8
1.52
4.18
iu/l
—
7
44
19
65
2.98
4.47
6.4
3.0
—
—
—
0
0
15
37
4.12
4.42
1.0
1.0
—
—
—
0
0
39
192
2.09
4.32
1.4
1.4
—
—
—
0
0
170
1258
1.47
4.30
2.1
1.8
1266.45
1178.02
nmol/l
0.56
139
956
320
2664
1.38
4.11
3.4
2.4
76.04
78.53
nmol/l
0.81
291
2352
16
52
3.13
4.10
1.8
1.6
—
—
—
0
0
8
10
8.08
4.07
5.1
12.5
4.21
5.54
mmol/l
—
8
10
92
604
1.60
4.03
2.5
2.1
424.78
386.35
nmol/l
0.52
87
566
10
18
5.62
3.98
2.8
1.3
8.33
10.02
ug/l
—
10
18
500
4504
1.41
3.81
59.5
23.6
14.85
13.82
%
28.45
494
4458
600
5600
1.58
3.78
49.8
19.0
24.93
27.17
mg/l
1.17
569
4749
30
146
2.10
3.47
1.6
1.5
—
—
—
0
0
34
174
2.00
3.45
1.4
1.2
—
—
—
0
0
17
65
2.66
3.32
1.1
1.3
—
—
—
0
0
33
170
1.99
3.29
1.5
1.5
—
—
—
0
0
43
244
1.81
3.23
1.8
1.7
—
—
—
0
0
33
173
1.95
3.15
1.4
1.2
—
—
—
0
0
12
35
3.47
3.12
1.7
1.7
—
—
—
0
0
22
101
2.22
2.96
1.5
2.2
32.95
33.04
pg
0.03
22
101
28
142
2.01
2.94
1.6
1.5
—
—
—
0
0
153
1187
1.37
2.89
1.2
1.3
1.07
1.50
u/ml
0.40
42
314
45
269
1.72
2.86
2.0
1.8
—
—
—
0
0
11
33
3.37
2.82
1.8
2.0
—
—
—
0
0
87
612
1.48
2.82
1.9
1.9
1.66
1.60
%
0.18
73
519
103
751
1.44
2.78
22.9
8.2
—
—
—
0
0
34
189
1.84
2.75
1.3
1.5
0.03
0.09
iu/ml
—
9
43
5
6
8.38
2.75
1.6
1.3
—
—
—
0
0
16
66
2.46
2.72
1.5
1.7
—
—
—
0
0
16
66
2.46
2.72
1.5
1.7
—
—
—
0
0
16
66
2.46
2.72
1.5
1.7
—
—
—
0
0
200
2390
0.77
2.50
1.9
2.0
1.46
1.32
mmol/l
1.62
167
1955
42
258
1.67
2.45
1.5
1.7
0.14
0.34
mg/l
2.57
15
122
359
3188
1.26
2.42
5.4
4.2
0.00
0.00
estimate
-0.00
86
688
6
12
5.03
2.40
3.5
9.0
4.23
5.36
kpa
—
6
12
169
1375
1.30
2.28
2.9
3.2
2.49
2.46
mmol/l
1.61
144
1232
14
60
2.36
2.23
1.1
1.2
—
—
—
0
0
12
48
2.53
2.19
1.7
1.5
—
—
—
0
0
360
3225
1.25
2.15
5.4
4.3
0.00
2.30
estimate
0.50
87
707
22
116
1.93
2.13
1.6
1.5
—
—
—
0
0
23
124
1.88
2.09
1.3
1.3
—
137.50
—
0
8
403
3664
1.24
2.07
4.2
3.6
86.00
57.29
u/l
4.50
383
3408
5
10
5.03
2.07
1.0
1.4
—
—
—
0
0
26
148
1.79
2.01
1.2
1.2
—
22.29
—
0
7
329
2935
1.23
1.99
2.9
2.5
—
—
—
0
0
16
77
2.10
1.98
1.5
1.6
—
—
—
0
0
36
226
1.63
1.97
1.3
1.2
—
—
—
0
0
23
127
1.84
1.96
1.1
1.2
—
2.60
—
0
11
10
39
2.59
1.94
1.8
1.6
—
—
—
0
0
8
29
2.78
1.79
2.4
2.0
41.89
40.65
g/l
—
8
29
358
3249
1.21
1.75
5.4
4.2
0.20
0.46
estimate
0.24
75
659
24
140
1.74
1.74
1.1
1.2
—
—
—
0
0
544
5166
1.26
1.65
7.6
5.1
2.13
2.01
mu/l
1.41
521
4679
10
42
2.40
1.62
1.8
1.6
—
—
—
0
0
5
15
3.35
1.52
1.0
1.1
—
—
—
0
0
9
37
2.45
1.48
6.0
3.5
0.78
0.92
%
—
9
37
19
111
1.73
1.40
1.1
1.1
—
—
—
0
0
21
128
1.66
1.34
1.4
1.3
—
—
—
0
0
6
24
2.51
1.30
1.0
2.0
—
—
—
0
0
6
24
2.51
1.30
1.0
2.0
—
—
—
0
0
6
24
2.51
1.30
1.0
2.0
—
—
—
0
0
8
34
2.37
1.29
5.1
4.5
—
—
—
0
0
472
4465
1.18
1.25
65.6
24.9
327.39
332.26
g/l
21.06
464
4437
600
5809
1.26
1.24
69.6
23.2
138.99
139.61
mmol/l
5.91
592
5696
6
130
0.46
1.16
1.0
1.2
1.07
0.91
g/l
—
6
130
15
87
1.74
1.16
1.1
1.0
—
—
—
0
0
600
5818
1.25
1.15
70.1
23.4
4.08
4.01
mmol/l
8.22
590
5695
5
20
2.51
1.15
1.0
1.7
—
—
—
0
0
27
183
1.49
1.15
1.9
1.6
7048.32
16830.73
e6/l
1.37
19
132
8
155
0.51
1.15
1.9
3.6
17.92
465.64
u/ml
—
8
146
7
30
2.35
1.12
1.4
1.1
—
—
—
0
0
206
1841
1.17
1.09
5.9
4.3
0.00
0.01
estimate
0.96
77
624
13
74
1.77
1.07
1.5
1.2
1.87
1.65
nmol/l
0.26
13
65
20
129
1.57
1.06
1.1
1.1
—
4.19
—
0
14
561
5414
1.20
1.06
8.8
7.2
43.30
40.28
mmol/mol
9.39
534
5022
209
2309
0.86
1.00
4.1
4.7
21.82
21.41
%
0.15
83
1169
9
49
1.85
0.99
1.4
1.4
—
51.43
—
0
7
542
5227
1.18
0.97
6.4
4.6
1.34
1.30
mmol/l
0.67
514
4740
6
120
0.50
0.94
1.0
1.2
1.27
1.48
g/l
—
6
120
6
28
2.15
0.91
1.0
1.4
—
—
—
0
0
39
298
1.33
0.89
1.6
3.6
11646.63
4919.00
u/ml
0.24
31
254
8
43
1.87
0.87
1.1
1.2
—
—
—
0
0
6
30
2.01
0.87
1.0
1.9
—
—
—
0
0
6
30
2.01
0.87
1.0
1.9
—
—
—
0
0
6
30
2.01
0.87
1.0
1.9
—
—
—
0
0
6
30
2.01
0.87
1.0
1.9
—
—
—
0
0
33
432
0.75
0.84
1.2
1.4
—
—
—
0
0
10
58
1.73
0.80
2.1
1.2
—
—
—
0
0
556
5399
1.16
0.79
50.5
18.6
62.99
75.33
ml/min/173m2
28.27
537
5054
7
38
1.85
0.73
4.4
1.9
—
—
—
0
0
10
60
1.68
0.72
1.1
1.3
—
—
—
0
0
11
68
1.63
0.72
1.0
1.1
—
1.33
—
0
9
110
970
1.16
0.71
1.3
1.3
33.92
34.77
iu/ml
0.03
51
302
155
1706
0.88
0.69
5.0
3.7
0.04
0.08
estimate
0.22
70
539
7
43
1.63
0.67
1.4
1.1
103.29
99.79
pmol/l
—
7
43
25
191
1.32
0.61
1.2
1.4
—
—
—
0
0
5
30
1.67
0.61
1.0
1.1
—
20.94
—
0
14
5
30
1.67
0.61
3.2
1.5
0.13
0.28
nmol/l
—
5
19
597
5853
1.16
0.61
25.1
13.2
30.55
25.99
u/l
1.00
581
5673
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
25
193
1.31
0.58
1.8
2.6
82.78
80.84
ug/min
—
10
115
6
35
1.72
0.58
1.2
1.4
—
—
—
0
0
6
35
1.72
0.58
1.2
1.4
—
—
—
0
0
69
792
0.86
0.57
6.6
5.2
34.23
32.03
%
1.13
53
515
8
55
1.46
0.56
1.0
1.1
—
85.40
—
0
5
33
269
1.24
0.52
1.2
1.2
32.12
136.20
u/ml
—
9
92
7
45
1.56
0.49
2.9
2.3
—
131.33
—
0
6
273
2867
0.92
0.48
4.4
5.9
2.16
2.95
ug/l
1.20
237
2566
10
68
1.48
0.47
1.1
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
2.3
—
—
—
0
0
0
15
0.00
0.41
0.0
2.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
1.31
—
0
9
0
16
0.00
0.41
0.0
1.4
—
0.97
—
0
9
0
16
0.00
0.41
0.0
1.4
—
1.06
—
0
9
601
5925
1.12
0.40
66.6
25.5
110.53
84.10
umol/l
17.75
589
5846
0
18
0.00
0.40
0.0
1.8
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
11
148
0.74
0.39
1.2
1.3
—
—
—
0
0
5
78
0.64
0.36
1.0
3.5
12.00
27.92
u/ml
—
5
78
159
1686
0.93
0.35
2.9
3.4
0.67
0.79
ug/l
1.31
103
1144
553
5444
1.08
0.33
6.9
5.4
1.24
1.41
mmol/l
21.89
523
4978
6
47
1.28
0.32
1.2
1.3
—
—
—
0
0
6
47
1.28
0.32
1.2
1.3
—
—
—
0
0
11
83
1.33
0.32
2.2
1.5
—
—
—
0
0
7
55
1.28
0.30
1.4
1.0
—
—
—
0
0
60
656
0.91
0.28
3.3
2.5
10.70
13.25
nmol/l
1.62
54
584
14
113
1.24
0.27
1.1
1.8
548.79
261.89
mu/l
0.72
14
106
555
5478
1.07
0.26
6.9
5.5
3.93
4.44
mmol/l
27.15
534
5051
73
677
1.09
0.25
1.3
1.4
—
—
—
0
0
16
133
1.21
0.24
1.6
1.4
11.72
6.58
u/l
0.65
11
103
5
38
1.32
0.23
1.6
1.6
71.60
86.08
umol/l
—
5
38
5
41
1.22
0.22
1.8
2.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
44.65
—
0
11
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
0.27
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
11
89
1.24
0.21
3.9
1.9
11.84
10.36
mmol/l
0.47
11
89
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
149
1430
1.05
0.20
6.0
4.5
1.02
1.02
kg/l
1.18
101
968
10
80
1.25
0.20
1.3
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
10
81
1.24
0.19
1.3
1.6
—
—
—
0
0
10
81
1.24
0.19
1.3
1.6
—
—
—
0
0
25
223
1.13
0.18
1.1
1.0
—
—
—
0
0
9
80
1.13
0.15
1.2
1.6
—
—
—
0
0
9
80
1.13
0.15
1.2
1.6
—
—
—
0
0
9
81
1.11
0.15
1.2
1.6
—
—
—
0
0
16
181
0.88
0.14
1.8
2.0
226.06
213.13
pmol/l
0.23
16
168
19
211
0.90
0.13
1.3
3.3
41.42
62.84
u/ml
0.45
19
203
93
895
1.05
0.12
1.2
1.3
13.03
9.95
u/ml
0.20
35
319
10
85
1.18
0.12
1.0
1.1
—
12.07
—
0
20
550
5463
1.03
0.11
6.6
5.7
6.41
6.11
mmol/l
4.23
517
4945
139
1427
0.97
0.11
2.0
1.8
455.07
18228718.03
pmol/l
0.94
116
1174
18
198
0.91
0.11
1.3
1.4
241.67
269.33
ug/g
0.23
12
111
52
497
1.05
0.09
1.6
1.5
—
—
—
0
0
6
54
1.11
0.09
1.0
1.4
—
—
—
0
0
238
2414
0.98
0.08
5.8
4.3
0.03
0.03
estimate
0.07
74
581
23
245
0.94
0.07
1.2
1.9
—
—
—
0
0
9
102
0.88
0.06
1.4
2.3
—
—
—
0
0
561
5594
1.02
0.04
7.5
6.3
2.23
2.56
mmol/l
16.95
534
5130
26
270
0.96
0.03
1.2
2.0
—
—
—
0
0
77
759
1.02
0.02
2.3
4.4
16.73
26.95
ug/l
0.31
69
642
600
5992
1.01
0.01
71.0
28.7
223.78
238.93
e9/l
6.68
590
5865
600
5993
1.01
0.01
70.8
28.6
92.44
91.69
fl
3.01
592
5917
600
5994
1.01
0.00
71.0
28.6
4.36
4.45
e12/l
3.07
587
5843
600
5994
1.01
0.00
75.8
29.2
39.54
40.12
%
1.82
593
5912
23
225
1.02
0.00
2.0
2.0
35.00
41.26
nmol/l
0.66
23
214
18
176
1.02
0.00
1.6
1.5
—
—
—
0
0
600
5996
1.01
0.00
71.7
28.9
129.86
134.68
g/l
8.76
592
5917
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
89
0.90
-0.00
1.4
2.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.5
—
83.55
—
0
8
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
-0.00
7.4
3.2
23.40
55.49
u/ml
—
5
49
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
22.64
—
0
9
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
8
79
1.01
-0.00
2.6
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.5
—
0.50
—
0
6
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint I9_HEARTFAIL_AND_HYPERTCARDIOM and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| I9_HEARTFAIL_AND_HYPERTCARDIOM | 2.312 [1.99, 2.68] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.234 |
During the follow-up period (1.1.1998 — 31.12.2019), 625 out of 1166 females with I9_HEARTFAIL_AND_HYPERTCARDIOM died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| I9_HEARTFAIL_AND_HYPERTCARDIOM | 2.417 [2.08, 2.81] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.009 |
During the follow-up period (1.1.1998 — 31.12.2019), 885 out of 1729 males with I9_HEARTFAIL_AND_HYPERTCARDIOM died.
Mortality risk
Mortality risk for people of age
years, who have I9_HEARTFAIL_AND_HYPERTCARDIOM.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.211% | 0.397% |
| 5 | 1.164% | 2.836% |
| 10 | 3.2% | 7.472% |
| 15 | 6.537% | 13.271% |
| 20 | 10.87% | 22.039% |
Relationships between endpoints
↥Index endpoint: I9_HEARTFAIL_AND_HYPERTCARDIOM – Heart failure and hypertrophic cardiomyopathy
GWS hits: 9
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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