Mononeuritis multiplex

G6_MONNEURMPLX

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — G58.7 Hospital discharge: ICD-9 — 3545 Cause of death: ICD-10 — G58.7 Cause of death: ICD-9 — 3545 2 out of 7 registries used, show all original rules.	111
4. Check minimum number of events None	111
5. Include endpoints None	111
6. Filter based on genotype QC (FinnGen only)	103

Control definitions (FinnGen only)

Control exclude: G6_NERPLEX

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: G58
Name in latin: Mononeuropathia multiplex

NAME	G6_MONNEURMPLX
CONTROL_EXCLUDE	G6_NERPLEX
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	G587
HD_ICD_9	3545
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	G587
COD_ICD_9	3545
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Mononeuritis multiplex based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	592	287	300
Only index persons	504	254	250
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	54.09	53.93	54.18
Only index persons	52.78	52.21	53.36

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	103	48	55
Unadjusted period prevalence (%)	0.02	0.02	0.03
Median age at first event (years)	55.08	53.24	56.69

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
105: Matched controls
1050

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

G58.7

ICD-10 Finland

Mononeuritis multiplex

3730.9

105.7

N03AX16

ATC

[U] pregabalin

9.5

30.5

113

3545A

ICD-9 Finland

Mononeuritis of upper limb and mononeuritis multiplex, Mononeuritis multiplex

+∞

22.7

G62.9

ICD-10 Finland

Polyneuropathy, unspecified

21.9

19.2

N03AX12

ATC

[U] gabapentin; oral

6.5

17.8

N06AX21

ATC

duloxetine; oral

7.9

16.4

ACC51

NOMESCO Finland

Release of median nerve

+∞

11.7

R29.8

ICD-10 Finland

Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems

6.1

11.6

G56.0

ICD-10 Finland

Carpal tunnel syndrome

15.2

11.1

G57.3

ICD-10 Finland

Lesion of lateral popliteal nerve

67.0

10.9

2402

FHL

External neurolysis of the nerve and possible alteration of the pathway (nerve pressure)

121.7

10.6

G56.2

ICD-10 Finland

Lesion of ulnar nerve

+∞

9.5

N02AX02

ATC

tramadol; systemic, rectal

3.2

8.0

292

M30.1

ICD-10 Finland

Polyarteritis with lung involvement [Churg-Strauss]

85.9

7.5

AA1CG

NOMESCO Finland

Extensive MRI examination of brain with high intensity magnet

4.7

7.1

L28

ICPC

Limited function/disability (L)

3.3

6.7

117

TAB00

NOMESCO Finland

Lumbar puncture

7.4

6.6

NH3AA

NOMESCO Finland

Foot and toes X-ray examination

4.7

6.3

ACC59

NOMESCO Finland

Decompression and freeing of adhesions of peripheral nerve: other or unspecified

+∞

6.3

M79.2

ICD-10 Finland

Neuralgia and neuritis, unspecified

13.6

6.2

R20.2

ICD-10 Finland

Paraesthesia of skin

6.1

NA3BG

NOMESCO Finland

Lumbar spine MRI examination with high intensity magnet

4.3

6.1

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3004588) Protein electrophoresis panel - Serum or Plasma

7.11

17.36

1.9

2.6

—

(3005719) IgG [Mass/volume] in Serum or Plasma

6.50

17.20

4.4

2.5

8.47

10.57

g/l

1.84

(3037522) Nuclear Ab [Titer] in Serum

113

5.53

15.73

1.4

1.3

595.56

469.63

titre

—

(3001334) Neutrophil cytoplasmic Ab [Units/volume] in Serum

12.60

13.37

1.4

1.8

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

11.11

11.16

2.8

1.5

1.11

1.20

g/l

0.60

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

12.60

10.81

1.7

1.1

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

10.46

10.36

2.8

1.5

0.21

0.23

g/l

0.23

(3016018) Differential panel - Cerebral spinal fluid

29.29

10.08

1.6

1.0

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

4.98

9.59

1.3

1.4

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

131

3.36

7.20

1.9

1.7

—

(3044290) Cell count panel - Cerebral spinal fluid

8.55

7.20

1.7

1.3

—

(3016543) Leukocytes [#/volume] in Cerebral spinal fluid

7.66

7.14

1.4

1.1

429.80

2.79

e6/l

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

120

3.40

7.06

1.7

1.5

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

7.06

6.79

1.2

1.1

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

13.47

6.75

1.1

1.0

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

13.47

6.75

1.1

1.0

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

11.11

6.73

1.3

1.0

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

9.10

6.56

1.3

1.1

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

10.25

6.48

1.3

1.0

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

3.47

6.34

1.5

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

11.00

6.20

1.8

2.4

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

516

2.99

5.83

14.2

11.2

3.85

4.04

e9/l

0.38

452

(3001604) Monocytes [#/volume] in Blood

460

2.80

5.69

11.9

6.2

0.63

0.58

e9/l

0.93

390

(3019198) Lymphocytes [#/volume] in Blood

473

2.78

5.56

11.9

6.3

1.79

2.09

e9/l

0.61

414

(3006315) Basophils [#/volume] in Blood

464

2.76

5.53

12.0

6.2

0.05

0.04

e9/l

2.26

393

(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis

5.46

5.37

2.2

3.9

0.00

1.02

g/l

1.33

(3013115) Eosinophils [#/volume] in Blood

480

2.71

5.28

12.2

6.3

0.22

0.18

e9/l

0.71

414

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

6.29

5.26

2.3

4.8

0.00

g/l

-0.00

(3023410) Appearance of Cerebral spinal fluid

14.28

5.17

1.9

1.2

—

(3044927) Protein electrophoresis panel - Urine

14.28

5.17

1.0

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

6.63

5.08

1.4

1.2

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

402

2.52

4.99

6.4

4.6

35.79

35.38

g/l

0.18

385

(42870588) Differential panel, method unspecified - Blood

298

2.38

4.54

12.1

6.0

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

303

2.33

4.32

2.5

3.3

1032.74

1342.04

ng/l

0.26

264

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

3.45

4.29

1.9

1.6

—

(4062490) Immunoglobulin typing, IgG

9.27

3.83

1.0

1.1

—

(42529582) MDA5 Ab [Presence] in Serum by Line blot

12.60

3.81

1.0

—

(42529598) SUMO-activating enzyme subunit 1 Ab [Presence] in Serum by Line blot

12.60

3.81

1.0

—

(42528593) TIF1-gamma Ab [Presence] in Serum by Line blot

12.60

3.81

1.0

—

(3013637) Mi-2 Ab [Presence] in Serum

12.60

3.81

1.0

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

163

2.39

3.78

2.5

2.0

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

4.09

3.75

2.8

2.4

—

(3007853) Bacteria identified in Skin by Aerobe culture

101

2.64

3.69

2.9

1.6

—

(4094501) Cardiovascular stress test using bicycle ergometer

5.14

3.66

1.0

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

3.97

3.65

1.8

2.2

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

4.91

3.53

1.3

1.8

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

4.10

3.52

1.9

2.0

—

(3023368) Bacteria identified in Blood by Culture

265

2.14

3.44

6.6

4.3

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

127

2.39

3.33

1.2

1.3

1.40

8.76

u/ml

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

469

2.10

3.27

8.8

7.1

1.22

1.21

mmol/l

0.47

413

(3044640) Blood type and Crossmatch panel - Blood

297

2.05

3.18

3.0

2.4

—

(3019309) Folate [Moles/volume] in Red Blood Cells

167

2.22

3.16

2.0

1.6

964.95

1312.73

nmol/l

1.81

133

(3042936) Bacteria identified in Isolate by Culture

130

2.33

3.15

2.5

1.9

—

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

10.40

3.01

1.4

1.0

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

10.40

3.01

1.4

1.2

—

(3000492) Spirometry study

2.54

2.99

1.6

—

(40760888) Immunoglobulin light chains.free panel - Serum

5.00

2.98

1.6

3.8

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

5.00

2.98

1.6

1.4

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

6.99

2.91

1.0

—

(3009595) Pneumocystis jirovecii DNA [Presence] in Specimen by NAA with probe detection

6.99

2.91

1.2

2.3

—

(3007164) IgA [Mass/volume] in Serum or Plasma

182

2.09

2.82

2.7

1.4

1.75

2.66

g/l

2.69

110

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

390

1.93

2.78

3.3

2.2

79.45

77.58

nmol/l

0.19

343

(3026179) Normetanephrine [Moles/volume] in Serum or Plasma

8.67

2.78

1.4

1.3

0.60

0.40

nmol/l

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

145

2.16

2.75

1.3

57.29

27.35

iu/ml

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

4.47

2.74

1.4

1.3

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

421

1.92

2.69

3.8

2.8

—

estimate

—

(3003129) Base excess in Capillary blood by calculation

5.71

2.58

1.5

2.5

1.88

2.15

mmol/l

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

4.61

2.52

1.7

1.4

—

(3013707) Erythrocyte sedimentation rate [Velocity] in Red Blood Cells by Westergren method

662

2.09

2.52

8.6

4.2

13.66

12.83

mm/h

0.15

606

(3003458) Phosphate [Moles/volume] in Serum or Plasma

120

2.17

2.50

7.0

5.0

1.03

mmol/l

0.04

114

(3015736) pH of Urine

383

1.84

2.44

3.9

3.4

6.09

6.26

0.42

218

(21494815) CD4 cells/Lymphocytes in Specimen

6.49

2.40

4.4

2.6

58.40

35.01

—

(3019832) Treponema pallidum Ab [Presence] in Serum

2.54

2.33

2.2

1.7

—

(3003327) Ova and parasites identified in Stool by Light microscopy

3.68

2.32

1.8

1.9

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

416

1.81

2.30

2.7

2.0

92.98

94.61

pmol/l

0.10

199

(3014148) Varicella zoster virus Ab [Titer] in Serum

5.77

2.24

1.4

1.1

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

4.47

2.18

1.3

1.1

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

223

1.85

2.18

3.2

2.4

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

303

1.78

2.12

2.4

2.3

56.82

85.93

u/l

0.74

277

(3045414) Leukocytes [Presence] in Urine

2.22

2.10

2.4

2.1

0.00

0.14

estimate

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

5.19

2.09

1.0

1.3

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

4.17

2.07

2.0

1.2

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

388

1.74

2.05

4.7

3.8

31.62

41.49

ng/l

0.42

284

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

122

2.02

2.04

2.5

1.7

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

3.49

2.00

1.7

2.0

—

(3037756) Immunofixation for Serum or Plasma

3.33

1.91

1.9

1.6

—

(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay

3.01

1.90

1.3

2.4

193.50

218.07

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

3.68

1.86

2.0

1.2

—

(3004616) Nuclear Ab [Presence] in Serum

4.32

1.84

1.0

1.2

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

585

1.73

1.82

3.8

3.2

46.44

49.52

u/l

0.19

543

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

3.47

1.77

1.8

1.6

—

(40760892) CBC W Ordered Manual Differential panel - Blood

202

1.76

6.5

5.3

—

(3020779) Urea [Moles/volume] in Serum or Plasma

2.09

1.76

9.0

5.2

13.13

9.49

mmol/l

1.05

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

137

1.87

1.73

4.2

2.0

22.63

22.22

0.05

127

(3032080) INR in Blood by Coagulation assay

469

1.65

1.72

16.3

14.2

1.26

1.28

inr

0.13

383

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

327

1.66

1.71

5.2

3.3

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

146

1.83

1.70

4.6

7.7

103.83

103.87

mmol/l

0.01

146

(3002179) Metamyelocytes/Leukocytes in Blood

2.08

1.64

7.0

4.7

0.43

0.61

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

3.12

1.60

1.8

1.6

—

(3041096) Erythrocytes [Presence] in Urine by Automated

260

1.65

1.58

5.6

3.1

0.00

estimate

-0.00

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.94

1.47

3.5

3.2

—

(3035350) Ketones [Presence] in Urine by Test strip

491

1.58

1.46

5.4

3.8

0.00

15.92

estimate

0.50

102

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

2.83

1.45

1.8

1.6

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

2.83

1.45

3.2

1.4

—

(3026008) Bacteria identified in Urine by Culture

274

1.61

1.45

3.5

2.9

—

(4035726) Immunohistochemistry procedure

1.90

1.45

1.2

1.4

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

464

1.56

1.41

2.8

3.0

—

(3000494) Fungus identified in Specimen by Culture

114

1.81

1.40

1.4

1.5

—

(3009508) Creatinine [Moles/volume] in Urine

341

1.56

1.39

3.7

3.2

6.74

7.55

mmol/l

0.81

291

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

3.03

1.37

1.8

1.4

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

3.03

1.37

1.8

1.4

—

(3021601) Nitrite [Presence] in Urine by Test strip

488

1.54

1.33

5.4

3.8

0.00

estimate

-0.00

100

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

2.46

1.32

1.9

1.8

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

2.59

1.32

1.8

1.7

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.98

1.30

1.9

1.5

—

(3042111) Morphology [Interpretation] in Bone marrow Narrative

2.86

1.30

1.2

1.9

—

(3021440) Promyelocytes/Leukocytes in Blood

1.92

1.28

8.7

4.8

0.00

0.09

—

(3025159) Blasts/Leukocytes in Blood

1.87

1.27

8.7

4.9

0.00

0.04

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

820

1.82

1.27

6.5

4.9

1.75

1.94

mu/l

0.84

740

(4010399) Spirometry for bronchospasm with prolonged evaluation after bronchodilator

1.89

1.24

1.7

1.3

—

(3012516) Albumin [Mass/volume] in Urine

330

1.51

1.22

3.4

3.3

58.46

67.65

mg/l

0.11

212

(40768797) Stomach Pathology biopsy report

120

1.71

1.19

1.5

1.3

—

(3029937) Albumin [Presence] in Urine by Test strip

286

1.52

1.18

5.7

3.9

0.00

estimate

-0.00

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

121

1.70

1.15

2.8

1.8

—

(3014051) Protein [Presence] in Urine by Test strip

243

1.52

1.12

3.7

2.9

—

0.00

—

(3009261) Glucose [Presence] in Urine by Test strip

500

1.47

1.11

5.5

3.9

0.00

0.04

estimate

0.49

(3022313) Gas panel - Capillary blood

2.02

1.10

3.3

2.7

—

(3028626) Oxygen [Partial pressure] in Capillary blood

2.45

1.10

2.0

1.9

8.54

8.29

kpa

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

2.20

1.08

1.7

—

(3018418) pH of Serum or Plasma

282

1.48

1.07

7.0

4.2

7.41

7.40

0.75

198

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.98

1.05

2.4

1.6

—

(3012544) pH of Venous blood

101

1.69

1.00

4.2

3.1

7.36

7.40

—

(3017181) Myelocytes/Leukocytes in Blood

1.72

0.96

9.0

4.7

0.67

1.02

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

1.90

0.96

5.1

2.9

24.20

24.02

mmol/l

—

(3021589) Normoblasts [#/volume] in Blood

401

1.42

0.95

17.2

12.9

0.00

0.01

e9/l

0.53

329

(1761868) Lipid panel - Serum or Plasma

324

0.66

0.95

3.3

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

2.29

0.95

1.8

1.6

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

2.06

0.88

1.8

1.6

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.83

0.87

2.8

1.7

—

(3020682) Albumin/Creatinine [Ratio] in Urine

340

1.39

0.85

4.3

4.0

7.34

10.63

mg/mmol

0.37

205

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

1.93

0.83

1.3

—

(3021960) Folate [Moles/volume] in Serum or Plasma

288

1.38

0.77

1.6

17.60

20.97

nmol/l

1.07

226

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

374

1.36

0.76

5.1

3.7

0.00

estimate

-0.00

(3010421) pH of Blood

2.14

0.75

6.0

3.6

7.40

7.41

—

(40758558) Short blood count panel - Blood

299

1.37

0.75

7.4

6.4

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

1.64

0.68

4.2

10.7

2.13

1.33

0.87

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.68

0.64

1.1

1.3

—

(3049717) Cytology report of Urine Cyto stain

1.70

0.62

4.0

3.8

—

(40768800) Prostate Pathology biopsy report

0.00

0.59

0.0

1.2

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.52

0.59

5.3

8.5

23.15

24.89

mmol/l

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

144

1.39

0.55

4.8

3.0

4.75

2.30

e6/l

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

181

1.35

0.54

4.5

3.4

1348.39

158.59

ng/l

0.42

143

(3002256) Pathology report gross observation

127

1.40

0.54

2.0

1.3

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

209

1.32

0.53

1.7

1.8

0.85

1.24

mg/l

0.54

167

(3030467) Casts [#/volume] in Urine by Automated count

266

1.29

0.52

5.6

3.1

0.54

0.29

e6/l

0.53

194

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.48

0.52

1.5

1.6

—

(40761536) Microorganisms panel - Urine sediment

1.54

0.52

7.1

3.7

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

886

1.43

0.50

30.6

15.9

21.87

25.52

mg/l

0.57

729

(3000991) Gas panel - Venous blood

1.46

0.49

6.4

9.3

—

(3003694) ABO and Rh group [Type] in Blood

259

1.28

0.48

1.5

1.3

—

(3002582) Erythrocytes [#/volume] in Urine

307

1.26

0.48

5.6

3.2

19.83

43.19

e6/l

1.13

234

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

1.50

0.46

4.2

10.8

0.79

0.72

—

(3002385) Erythrocyte [DistWidth] in Red Blood Cells

732

0.80

0.46

36.4

20.5

13.87

13.78

0.29

726

(3019977) pH of Arterial blood

113

1.38

0.46

4.3

8.4

7.43

7.42

—

(3043409) Potassium [Moles/volume] in Arterial blood

1.59

0.43

1.4

4.3

3.86

3.95

mmol/l

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

1.41

0.43

2.8

2.5

0.66

0.64

—

(40768804) Tissue Pathology biopsy report

370

1.23

0.41

2.7

2.1

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

0.00

0.41

0.0

1.9

—

6.59

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

881

1.36

0.41

6.1

5.2

5.93

6.02

mmol/l

0.34

812

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.40

0.0

2.8

—

56.72

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

135

0.71

0.39

1.9

1.5

—

(3019150) Specific gravity of Urine by Refractometry

219

1.25

0.38

4.3

4.2

1.02

kg/l

1.11

147

(40768443) Skin Pathology biopsy report

1.35

0.34

1.3

1.2

—

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

1.33

0.31

3.2

2.1

0.19

0.21

g/l

0.45

(3025941) Bacteria identified in Stool by Culture

1.32

0.31

1.1

1.3

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

159

1.24

0.29

4.9

2.9

1.85

1.00

e6/l

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

1.33

0.27

3.8

2.5

108.30

136.86

ng/l

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

221

0.83

0.25

3.5

3.0

0.54

0.74

ug/l

1.06

147

(3018095) Leukocytes [#/volume] in Urine

348

1.14

0.22

7.4

3.8

46.70

125.84

e6/l

0.72

249

(3007930) Methemoglobin/Hemoglobin.total in Blood

1.23

0.22

3.2

4.0

0.70

0.85

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

1.23

0.22

1.2

—

(3000963) Hemoglobin [Mass/volume] in Blood

961

0.79

0.22

44.9

25.1

132.99

134.98

g/l

0.56

952

(3010813) Leukocytes [#/volume] in Blood

961

0.79

0.22

44.6

25.0

6.90

6.78

e9/l

0.22

942

(3009542) Hematocrit [Volume Fraction] of Blood by calculation

961

0.79

0.22

44.9

25.5

39.46

40.32

0.57

952

(3035941) MCH [Entitic mass]

961

0.79

0.22

44.3

24.9

30.36

30.45

0.19

952

(3026361) Erythrocytes [#/volume] in Blood

961

0.79

0.22

44.5

25.0

4.42

4.47

e12/l

0.38

942

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.21

0.0

1.0

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.21

0.0

1.0

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

0.21

0.0

3.2

—

1.00

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

0.21

0.0

1.3

—

(1002224) Polysomnography panel

1.29

0.21

1.2

1.1

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.21

0.0

1.5

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

0.21

0.0

1.5

—

0.99

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.21

0.0

1.5

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.21

0.0

1.5

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

0.21

0.0

1.5

—

0.94

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.21

0.0

1.2

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.21

0.0

1.2

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

0.21

0.0

1.5

—

1.07

—

(3008401) Mugwort IgE Ab [Units/volume] in Serum

0.00

0.20

0.0

1.1

—

1.51

—

(3003888) Timothy IgE Ab [Units/volume] in Serum

0.00

0.20

0.0

1.1

—

7.15

—

(3024731) MCV [Entitic mean volume] in Red Blood Cells

960

0.80

0.20

44.4

25.0

91.43

91.48

0.04

951

(3007461) Platelets [#/volume] in Blood

960

0.80

0.20

44.6

25.0

250.12

246.81

e9/l

0.22

944

(3020891) Body temperature

1.16

0.19

3.8

4.3

36.98

37.01

°c

—

(3022145) Colonoscopy Study observation

100

1.23

0.19

1.4

1.3

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

1.18

0.18

3.0

2.5

1.29

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

296

0.88

0.17

4.2

21.01

21.92

0.11

142

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

130

0.83

0.17

2.0

1.4

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

851

1.13

0.13

4.5

4.4

1.32

1.28

mmol/l

0.23

786

(3023081) Carboxyhemoglobin/Hemoglobin.total in Blood

1.04

0.09

3.2

3.8

1.60

1.53

—

(21494755) Public health laboratory ask at order entry panel

0.80

0.08

1.3

1.4

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

951

0.89

0.06

38.5

21.5

86.05

78.72

umol/l

0.84

941

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

119

1.11

0.06

5.5

8.4

—

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

100

1.11

0.05

2.4

1.7

1.67

1.60

0.14

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

940

0.91

0.05

20.2

12.7

26.13

25.80

u/l

0.09

910

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

882

1.06

0.02

5.2

5.3

1.45

mmol/l

0.01

816

(3019550) Sodium [Moles/volume] in Serum or Plasma

923

1.07

0.02

30.6

19.0

139.53

139.55

mmol/l

0.04

904

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

885

0.97

0.00

5.3

5.4

4.33

4.58

mmol/l

1.69

825

(40761511) CBC panel - Blood by Automated count

914

0.97

0.00

24.2

14.6

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

925

1.05

0.00

31.4

19.0

3.99

3.98

mmol/l

0.09

905

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

901

0.99

0.00

6.4

6.2

2.48

2.67

mmol/l

1.53

840

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

0.0

2.1

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3019060) Gas panel - Arterial blood

1.02

0.00

1.7

4.0

—

(3017315) Amylase [Enzymatic activity/volume] in Urine

0.00

-0.00

0.0

1.0

—

1694.50

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

-0.00

0.0

3.8

—

(3019897) Erythrocyte [DistWidth] in Red Blood Cells by Automated count

0.00

-0.00

0.0

2.8

—

13.45

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

-0.00

0.0

1.0

—

(3009871) Measles virus Ab [Titer] in Serum

0.00

-0.00

0.0

1.6

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

-0.00

0.0

1.2

—

(36306090) Helicobacter pylori [Presence] in Tissue by Organism specific culture

0.00

-0.00

0.0

1.0

—

(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells

0.00

-0.00

0.0

3.0

—

(3006442) Creatine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.1

—

69.29

—

(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture

0.00

-0.00

0.0

2.3

—

(3028433) Virus identified in Specimen by Culture

0.00

-0.00

0.0

1.0

—

(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells

0.00

-0.00

0.0

3.0

—

(3014271) Vancomycin [Susceptibility]

0.00

-0.00

0.0

2.0

—

(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(36660697) Celiac disease serology panel - Serum

0.98

-0.00

1.3

—

(40757494) Bilirubin.total [Moles/volume] in Blood

0.00

-0.00

0.0

1.7

—

(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

-0.00

0.0

1.0

—

120.60

—

(40765096) Chromosome analysis panel by Banding

0.00

-0.00

0.0

1.1

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

-0.00

0.0

1.4

—

(3009306) Alpha-1-Fetoprotein [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.7

—

4.27

—

Mortality – FinRegistry

↥

Association

Association between endpoint G6_MONNEURMPLX and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have G6_MONNEURMPLX.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: G6_MONNEURMPLX – Mononeuritis multiplex

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Mononeuritis multiplex

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints