myocardial infarction: Gross necrosis of the myocardium, as a result of interruption of the blood supply to the area, as in coronary thrombosis.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
391 |
4. Check minimum number of eventsNone |
391 |
5. Include endpointsNone |
391 |
6. Filter based on genotype QC (FinnGen only) |
341 |
Control definitions (FinnGen only)
- Control exclude
- I9_ISCHHEART
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- I20-I25
- Name in latin
- Aliquae complicationes post infarctum myocardii acutum
Similar endpoints
↥List of similar endpoints to
Complications following myocardial infarction
based on the number of shared cases.
Similar with more cases:
- Ischaemic heart disease, wide definition
- Ischemic heart diseases
- Cardiovascular diseases (excluding rheumatic etc)
- Cardiovascular diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4502 | 1945 | 2459 |
| Only index persons | 2275 | 934 | 1341 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.06 | 0.07 |
| Only index persons | 0.04 | 0.03 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 74.10 | 77.64 | 71.22 |
| Only index persons | 72.79 | 77.27 | 69.66 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 341 | 99 | 242 |
| Unadjusted period prevalence (%) | 0.09 | 0.04 | 0.11 |
| Median age at first event (years) | 72.65 | 73.75 | 72.21 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 348
- Matched controls
- 3480
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I25.1
ICD-10 Finland
Atherosclerotic heart disease
169.0
272.2
135
13
I23.0
ICD-10 Finland
Haemopericardium as current complication following acute myocardial infarction
+∞
221.2
188
*
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
30.3
158.2
114
55
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
+∞
134.3
120
*
I25.2
ICD-10 Finland
Old myocardial infarction
+∞
90.7
83
*
I21.9
ICD-10 Finland
Acute myocardial infarction, unspecified
+∞
68.0
63
*
81
HP
Angiography of the heart and coronary arteries
30.5
63.7
43
16
AN1
HP
Coronary angiography
191.5
62.2
63
*
C01DA14
ATC
isosorbide mononitrate; oral
9.2
59.5
83
115
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
176.9
57.9
59
*
I21.0
ICD-10 Finland
Acute transmural myocardial infarction of anterior wall
+∞
55.7
52
*
FN1AT
NOMESCO Finland
Endovascular dilatation of coronary arteries (PTCA)
+∞
46.9
44
*
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
+∞
44.8
42
*
I21.2
ICD-10 Finland
Acute transmural myocardial infarction of other sites
+∞
40.4
38
*
I23.6
ICD-10 Finland
Thrombosis of atrium, auricular appendage, and ventricle as current complications following acute myocardial infarction
+∞
40.4
38
*
I21.1
ICD-10 Finland
Acute transmural myocardial infarction of inferior wall
+∞
38.2
36
*
I23.1
ICD-10 Finland
Atrial septal defect as current complication following acute myocardial infarction
+∞
38.2
36
*
Z95.1
ICD-10 Finland
Presence of aortocoronary bypass graft
+∞
36.1
34
*
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
4.7
34.4
100
275
FN2BA
NOMESCO Finland
Percutaneous transluminal coronary angioplasty with stent (includes balloon pre-dilation)
+∞
33.9
32
*
I23.2
ICD-10 Finland
Ventricular septal defect as current complication following acute myocardial infarction
+∞
33.9
32
*
FN1YT
NOMESCO Finland
Percutaneous insertion of coronary artery stent
+∞
33.9
32
*
213
Kela drug reimbursment
Fat metabolism disorder associated with chronic coronary artery disease
39.6
33.7
42
12
I23.8
ICD-10 Finland
Other current complications following acute myocardial infarction
+∞
31.8
30
*
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
342.1
31.4
31
*
I20.09
ICD-10 Finland
Unstable angina
+∞
29.6
28
*
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
+∞
29.6
28
*
I20.99
ICD-10 Finland
Angina pectoris, unspecified
105.2
27.1
29
*
B01AC04
ATC
clopidogrel; oral
4.7
26.4
71
181
FNA01
NOMESCO Finland
Anastomosis to coronary artery from internal mammary artery, one distal anastamosis
+∞
26.4
25
*
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
78.6
26.2
29
*
I21.41
ICD-10 Finland
Acute subendocardial infarction stenosed coronary artery
+∞
25.3
24
*
I21.01
ICD-10 Finland
Acute transmural myocardial infarction of anterior wall
+∞
25.3
24
*
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
140.1
25.0
26
*
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
3.7
24.9
101
347
I21.99
ICD-10 Finland
Myocardial infarction (acute) UNS unspecified coronary artery status
+∞
24.2
23
*
Z95.5
ICD-10 Finland
Presence of coronary angioplasty implant and graft
245.5
22.9
23
*
I21.19
ICD-10 Finland
Acute transmural myocardial infarction of inferior wall
+∞
21.0
20
*
I20.90
ICD-10 Finland
Angina pectoris, unspecified
+∞
21.0
20
*
I20.01
ICD-10 Finland
Unstable angina
+∞
20.0
19
*
I21.09
ICD-10 Finland
Acute transmural myocardial infarction of anterior wall
+∞
18.9
18
*
I25.5
ICD-10 Finland
Ischaemic cardiomyopathy
+∞
18.9
18
*
AN3
HP
Balloon angioplasty and metallic stent
+∞
18.9
18
*
201
Kela drug reimbursment
Chronic cardiac insufficiency
5.4
18.3
38
77
I21.00
ICD-10 Finland
Acute transmural myocardial infarction of anterior wall
+∞
17.9
17
*
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
7.1
17.3
27
41
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.2
17.0
81
301
82
HP
Single vessel balloon catheter extension
+∞
16.8
16
*
11
HP
Coronary artery bypass surgery
+∞
16.8
16
*
I21.11
ICD-10 Finland
Acute transmural myocardial infarction of inferior wall
+∞
16.8
16
*
I20.00
ICD-10 Finland
Unstable angina
178.2
16.6
17
*
B01AA03
ATC
warfarin; systemic
2.6
14.8
115
552
I20.89
ICD-10 Finland
Other angina pectoris unspecified coronary artery status
83.7
14.7
16
*
I23.5
ICD-10 Finland
Rupture of papillary muscle as current complication following acute myocardial infarction
+∞
14.7
14
*
I21.10
ICD-10 Finland
Acute transmural myocardial infarction of inferior wall
+∞
14.7
14
*
B01AC06
ATC
acetylsalicylic acid; oral
17.1
13.6
21
13
AN2
HP
Balloon angioplasty, including several vessels
+∞
13.6
13
*
FXG00
NOMESCO Finland
Insertion and use of IABP
+∞
13.6
13
*
I21.90
ICD-10 Finland
Myocardial infarction (acute) UNS no detected stenosis of the coronary artery
+∞
13.6
13
*
FNC20
NOMESCO Finland
Aorto-coronary venous bypass with two distal anastomoses
+∞
13.6
13
*
I50.1
ICD-10 Finland
Left ventricular failure
5.2
13.6
29
60
R99
ICD-10 Finland
Other ill-defined and unspecified causes of mortality
5.4
13.4
27
53
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
3.0
13.3
68
261
C09AA05
ATC
ramipril; oral
2.4
12.6
111
560
I21.40
ICD-10 Finland
Acute subendocardial infarction no detected stenosis of the coronary artery
+∞
12.6
12
*
AA1
HP
Conventional CABG
+∞
12.6
12
*
C07AB02
ATC
metoprolol; systemic
2.6
11.6
83
378
AN4
HP
Balloon angioplasty and drug eluding stent
+∞
11.5
11
*
AP1
HP
Catheterization of the left side of the heart
+∞
11.5
11
*
4100X
ICD-9 Finland
Acute myocardial infarction, Of anterolateral wall[INFARCTUS MYOCARDII ACUTUS DEFINITUS,MÄÄRITTELEMÄT]
+∞
11.5
11
*
WX872
NOMESCO Finland
Intensive care
8.4
10.8
23
29
K76
ICPC
Ischaemic heart dis without angina
61.9
10.7
12
*
FHA20
NOMESCO Finland
Closure of VSR in posteroseptal myocardial infarction
+∞
10.5
10
*
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
4.0
10.1
30
81
B01AC24
ATC
ticagrelor; oral
102.7
9.5
10
*
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
31.0
9.5
12
*
FNC30
NOMESCO Finland
Aorto-coronary venous bypass with three distal anastomoses
+∞
9.4
9
*
FNC10
NOMESCO Finland
Aorto-coronary venous bypass with single distal anastomosis
+∞
9.4
9
*
FL1AC
NOMESCO Finland
Left cardioangiography
+∞
9.4
9
*
R07.4
ICD-10 Finland
Chest pain, unspecified
2.4
9.3
79
386
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.4
9.1
75
362
C01BD01
ATC
amiodarone; systemic
11.1
8.4
15
14
FN1BT
NOMESCO Finland
Extensive endovascular dilatation of coronary (PTCA) arteries
+∞
8.4
8
*
FN2AB
NOMESCO Finland
Percutaneous transluminal coronary angioplasty (PTCA), drug-eluting balloon
+∞
8.4
8
*
I23.3
ICD-10 Finland
Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
+∞
8.4
8
*
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
+∞
8.4
8
*
I25
ICD-10 Finland
Chronic ischaemic heart disease
17.7
8.1
12
7
C03DA01
ATC
spironolactone; oral
2.5
7.6
53
236
ZXD00
NOMESCO Finland
Emergency procedure
7.4
7.6
17
24
ZXD05
NOMESCO Finland
Urgent procedure
2.0
7.5
96
549
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
81.8
7.4
8
*
I21.97
ICD-10 Finland
Suspected acute myocardial infarction
81.8
7.4
8
*
I23
ICD-10 Finland
Certain current complications following acute myocardial infarction
+∞
7.3
7
*
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.5
7.3
47
202
I50.9
ICD-10 Finland
Heart failure, unspecified
2.1
7.2
74
390
C08CA07
ATC
nisoldipine; oral
17.1
6.8
10
6
A98
ICPC
Health maint/preventive medicine
0.6
6.7
191
2392
I47.2
ICD-10 Finland
Ventricular tachycardia
8.1
6.7
14
18
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
10.3
6.6
12
12
280
Kela drug reimbursment
Clopidogrel
71.1
6.4
7
*
61
HP
Catheterization and pressure measurement of the left side of the heart
18.4
6.3
9
5
FLC10
NOMESCO Finland
Repair of wall of left ventricle using patch
+∞
6.3
6
*
I21.4
ICD-10 Finland
Acute subendocardial myocardial infarction
+∞
6.3
6
*
I20.80
ICD-10 Finland
Other angina pectoris no detected stenosis of coronary artery
+∞
6.3
6
*
AM2
HP
Surgery of infarction complication eg VSR, aneurysm, rupture of papillary muscle
+∞
6.3
6
*
4120B
ICD-9 Finland
Old myocardial infarction[STATUS POST INFARCTUM CORDIS,AHTAUTUNUT]
+∞
6.3
6
*
FPG30
NOMESCO Finland
Implantation of cardioverter-defibrillator with ventricular electrode
+∞
6.3
6
*
I21.21
ICD-10 Finland
Acute transmural myocardial infarction with another location stenosed coronary artery
+∞
6.3
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
28
85
3.49
7.98
3.0
2.5
0.40
0.37
iu/ml
0.15
14
46
186
2390
0.52
7.96
14.8
12.1
25.53
24.67
u/l
0.25
173
2283
196
2464
0.53
7.50
38.3
27.0
233.36
236.37
e9/l
0.26
185
2389
196
2464
0.53
7.50
38.3
27.0
4.34
4.39
e12/l
0.67
184
2381
196
2464
0.53
7.50
38.7
27.2
130.57
132.83
g/l
0.97
187
2411
196
2464
0.53
7.50
40.1
27.5
39.36
39.35
%
0.01
186
2408
196
2464
0.53
7.50
38.3
27.0
92.03
91.95
fl
0.08
185
2411
42
168
2.71
7.50
3.6
1.9
11.51
3.88
ug/l
0.85
32
128
179
2310
0.54
7.46
28.5
18.1
31.64
29.75
mg/l
0.31
155
1946
166
2187
0.54
7.36
28.0
18.3
70.08
72.02
ml/min/173m2
0.59
156
2048
195
2450
0.54
7.35
34.1
24.1
92.72
86.24
umol/l
1.15
184
2397
194
2425
0.55
6.87
32.9
21.4
139.61
139.62
mmol/l
0.02
183
2355
195
2431
0.55
6.79
33.1
21.6
4.06
4.01
mmol/l
1.42
182
2360
41
814
0.44
6.00
3.0
3.6
1.03
0.77
ug/l
0.43
28
573
163
2080
0.59
5.40
5.7
4.9
2.11
2.07
mu/l
0.09
142
1819
67
1088
0.52
5.36
4.6
5.0
22.26
21.31
%
0.27
39
593
176
2197
0.60
5.26
6.1
5.6
2.42
2.65
mmol/l
2.47
159
1914
147
1916
0.60
5.20
11.2
8.1
87.85
84.17
u/l
0.43
135
1763
167
2098
0.61
4.95
5.5
4.9
1.32
1.44
mmol/l
4.01
151
1828
174
2154
0.62
4.72
7.2
6.8
42.85
39.81
mmol/mol
3.35
160
1936
171
2123
0.62
4.67
5.5
4.9
4.24
4.52
mmol/l
2.60
155
1881
178
2189
0.62
4.66
5.4
5.3
6.49
6.06
mmol/l
3.27
153
1909
134
1759
0.61
4.63
5.4
4.2
17.22
14.55
mm/h
0.86
120
1591
136
1779
0.61
4.63
33.4
22.7
14.37
13.91
%
2.51
131
1747
94
1344
0.59
4.58
4.9
6.4
2.63
3.58
ug/l
0.89
79
1181
73
1116
0.56
4.58
2.8
2.3
77.91
78.70
nmol/l
0.08
64
950
92
1319
0.59
4.51
4.1
4.3
0.18
1.03
estimate
0.39
22
295
92
1307
0.60
4.29
4.1
4.2
0.00
6.08
estimate
0.50
22
309
41
728
0.50
4.17
3.7
3.8
0.00
0.20
estimate
1.09
14
240
92
1289
0.61
3.96
4.1
4.3
0.00
0.00
estimate
-0.00
20
297
65
990
0.58
3.89
3.8
4.4
0.00
0.05
estimate
1.52
15
264
166
2009
0.67
3.41
4.8
4.1
1.41
1.25
mmol/l
2.32
149
1725
131
1658
0.66
3.35
5.0
3.9
15.25
15.18
pmol/l
0.10
112
1435
59
871
0.61
2.99
1.9
1.8
16.53
20.60
nmol/l
1.44
49
702
22
102
2.23
2.93
2.7
1.8
216.27
934.99
ug/l
0.93
22
95
109
1405
0.67
2.92
3.2
3.2
84.93
56.82
u/l
0.94
95
1290
76
1036
0.66
2.63
4.8
3.5
—
—
—
0
0
97
1245
0.69
2.41
2.4
2.3
91.71
93.51
pmol/l
0.16
62
656
87
1135
0.69
2.35
4.4
3.0
—
—
estimate
—
0
0
107
1343
0.71
2.32
13.0
9.7
5.17
4.37
e9/l
1.34
93
1134
112
874
1.42
2.31
4.2
2.7
2068.31
1607.64
ng/l
0.62
101
732
58
808
0.66
2.18
4.7
3.5
0.43
0.44
e6/l
0.04
47
605
60
827
0.67
2.14
1.7
1.9
1.42
1.28
mmol/l
0.75
51
647
56
770
0.67
1.96
3.8
4.1
0.00
0.00
estimate
-0.00
18
256
99
1227
0.73
1.89
6.7
4.8
32.92
34.37
g/l
1.61
88
1125
13
59
2.25
1.86
1.4
1.4
1.13
1.12
g/l
0.04
13
59
129
1533
0.75
1.84
7.6
4.5
7.65
6.81
mmol/l
1.92
124
1461
13
60
2.21
1.80
1.3
1.4
0.24
0.23
g/l
0.21
13
60
117
1406
0.75
1.79
10.2
6.5
1.20
1.21
mmol/l
1.06
96
1171
14
71
2.01
1.56
1.4
1.4
5.26
10.87
iu/ml
—
5
19
77
965
0.74
1.53
3.8
3.5
2.34
2.35
mmol/l
0.15
71
851
106
1269
0.76
1.52
9.2
5.8
1.19
1.21
mmol/l
1.73
97
1141
25
157
1.64
1.45
13.7
9.8
94.85
93.29
%
1.45
25
157
33
474
0.66
1.43
4.5
3.4
1.01
1.38
e6/l
0.30
17
260
85
1036
0.76
1.37
2.8
2.4
—
—
—
0
0
48
629
0.73
1.26
4.5
3.4
2.46
2.46
mmol/l
0.01
42
556
42
558
0.72
1.20
3.4
4.3
1.02
1.02
kg/l
1.37
26
373
36
487
0.71
1.15
4.4
3.2
0.81
1.19
e6/l
0.70
19
274
0
36
0.00
1.14
0.0
1.1
—
374.75
—
0
16
48
616
0.74
1.11
1.7
1.8
326316191.13
11609399.84
pmol/l
0.47
38
491
11
60
1.86
1.04
2.1
1.5
—
—
—
0
0
10
56
1.81
0.88
2.2
1.5
—
—
—
0
0
52
634
0.79
0.83
3.3
3.0
394.67
360.63
umol/l
0.91
45
531
74
862
0.82
0.78
3.8
4.2
8.54
8.87
mg/mmol
0.04
52
549
0
27
0.00
0.77
0.0
1.3
—
—
—
0
0
19
133
1.45
0.75
2.1
1.8
—
—
—
0
0
11
69
1.61
0.69
1.3
1.2
—
—
—
0
0
82
715
1.19
0.68
2.6
2.2
3.31
2.99
mg/l
0.45
64
602
5
28
1.80
0.66
1.0
1.0
—
—
—
0
0
11
70
1.59
0.66
1.3
1.2
—
—
—
0
0
57
483
1.22
0.64
6.9
2.9
4483.46
121.35
ng/l
1.21
50
411
0
21
0.00
0.60
0.0
1.2
—
7.23
—
0
15
36
294
1.25
0.57
11.2
6.9
0.19
0.95
mmol/l
0.56
27
239
55
474
1.19
0.53
1.8
1.6
2.26
1.86
mg/l
0.26
46
379
27
332
0.80
0.49
3.3
4.8
7.51
38.82
ug/l
0.79
21
273
26
315
0.81
0.43
2.7
3.7
—
—
—
0
0
8
56
1.44
0.43
1.4
1.4
—
—
—
0
0
8
56
1.44
0.43
1.4
1.4
—
—
—
0
0
26
314
0.81
0.42
1.3
1.3
53.21
40.22
iu/ml
—
10
104
16
123
1.32
0.41
2.2
1.7
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
0
18
0.00
0.40
0.0
1.6
—
—
—
0
0
21
256
0.81
0.37
2.5
2.8
0.44
0.81
e6/l
0.37
21
247
19
234
0.80
0.37
2.1
2.3
12.45
12.58
nmol/l
0.02
19
201
5
76
0.65
0.36
1.6
1.3
—
—
—
0
0
6
43
1.40
0.35
1.0
1.7
—
—
—
0
0
93
1002
0.90
0.34
3.6
2.7
127.02
182.39
ug/l
2.34
85
893
11
144
0.76
0.34
1.0
1.3
—
—
—
0
0
11
84
1.32
0.30
1.3
1.3
—
—
—
0
0
35
308
1.15
0.29
8.8
7.0
—
—
—
0
0
12
95
1.27
0.26
2.1
3.6
1.02
1.62
ratio
—
6
57
57
617
0.91
0.24
3.8
2.7
—
—
—
0
0
30
266
1.14
0.23
1.5
2.5
65.41
65.58
g/l
0.03
25
235
19
162
1.18
0.23
4.1
3.8
1.38
1.60
mmol/l
—
10
117
30
267
1.14
0.22
5.0
3.2
0.47
2.04
mmol/l
0.84
20
214
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
2.76
—
0
10
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
1.24
—
0
7
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
57
611
0.92
0.20
2.0
1.8
1272.00
1153.19
nmol/l
0.43
44
455
24
213
1.14
0.19
1.5
1.8
—
—
—
0
0
19
167
1.15
0.17
1.5
1.4
—
—
—
0
0
13
152
0.85
0.17
1.7
1.4
—
—
—
0
0
55
516
1.08
0.17
2.1
1.8
—
—
—
0
0
31
339
0.91
0.16
2.0
1.8
—
—
—
0
0
8
69
1.16
0.16
1.1
1.6
—
—
—
0
0
40
372
1.09
0.15
2.9
2.2
19.85
23.08
%
0.97
35
341
108
1042
1.05
0.14
5.1
3.5
370.76
27.53
ng/l
2.32
85
820
19
211
0.89
0.13
1.4
1.3
—
—
—
0
0
11
96
1.15
0.10
1.1
1.2
17.22
141.95
u/ml
—
6
32
5
45
1.11
0.10
1.2
1.4
—
—
—
0
0
20
184
1.09
0.09
2.5
2.6
62.20
59.92
ml/min/173m2
—
10
75
132
1348
0.97
0.09
44.5
15.2
1.64
1.33
inr
5.02
116
1118
22
204
1.08
0.09
1.9
1.6
—
—
—
0
0
5
61
0.82
0.08
1.2
1.5
—
0.02
—
0
15
20
186
1.08
0.07
1.6
1.8
1.49
1.69
%
0.87
20
154
36
373
0.96
0.05
2.1
1.7
—
—
—
0
0
10
109
0.91
0.04
1.3
1.2
—
—
—
0
0
42
410
1.03
0.03
2.8
2.2
2.22
2.19
g/l
0.12
36
368
12
128
0.94
0.02
2.6
2.9
—
—
—
0
0
30
298
1.01
0.00
1.2
1.3
10.49
18.90
u/ml
0.33
16
96
44
444
0.99
0.00
2.9
2.2
11.34
12.49
umol/l
0.57
39
403
44
436
1.01
0.00
1.4
1.2
0.65
0.87
u/ml
0.81
11
101
7
75
0.93
0.00
2.9
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
0
6
0.00
-0.00
0.0
2.0
—
185.50
—
0
6
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.0
—
75.20
—
0
5
0
6
0.00
-0.00
0.0
3.0
—
13.62
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
7
76
0.92
-0.00
2.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
8.80
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
5
0.00
-0.00
0.0
2.4
—
94.80
—
0
5
0
9
0.00
-0.00
0.0
1.6
—
935.00
—
0
9
0
5
0.00
-0.00
0.0
2.4
—
80.80
—
0
5
5
51
0.98
-0.00
1.4
1.6
—
—
—
0
0
6
65
0.92
-0.00
1.8
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
7
69
1.01
-0.00
1.1
1.6
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint I9_MI_COMPLICATIONS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| I9_MI_COMPLICATIONS | 2.357 [1.88, 2.95] | < 0.001 |
| Birth year | 0.999 [0.99, 1.01] | 0.801 |
During the follow-up period (1.1.1998 — 31.12.2019), 329 out of 499 females with I9_MI_COMPLICATIONS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| I9_MI_COMPLICATIONS | 2.412 [1.98, 2.93] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 427 out of 704 males with I9_MI_COMPLICATIONS died.
Mortality risk
Mortality risk for people of age
years, who have I9_MI_COMPLICATIONS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.256% | 0.471% |
| 5 | 1.612% | 2.737% |
| 10 | 4.016% | 6.797% |
| 15 | 7.708% | 13.221% |
| 20 | 13.262% | 21.439% |
Relationships between endpoints
↥Index endpoint: I9_MI_COMPLICATIONS – Complications following myocardial infarction
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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