Cyst of spleen

D3_CYSTSPLEEN

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D73.4
  • Cause of death: ICD-10 D73.4

2 out of 7 registries used, show all original rules.

69

4. Check minimum number of events

None

69

5. Include endpoints

None

69

6. Filter based on genotype QC (FinnGen only)

67

Control definitions (FinnGen only)

Control exclude
D3_BLOODOTHER

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D73
Name in latin
Cysta lienis

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: unknown.

No upset table: unknown.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 480 271 208
Only index persons 434 248 186
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 41.06 42.38 39.37
Only index persons 43.35 44.73 41.52

-FinnGen-

Key figures

All Female Male
Number of individuals 67 47 20
Unadjusted period prevalence (%) 0.01 0.02 0.01
Median age at first event (years) 46.86 47.11 46.29

-FinRegistry-

Age distribution of first events

0102030405060708090010203040506070AgeIndividuals

-FinnGen-

Age distribution of first events

01020304050607002468101214AgeIndividuals

-FinRegistry-

Year distribution of first events

1970197519801985199019952000200520102015202020220102030405060708090100110120130YearIndividuals

-FinnGen-

Year distribution of first events

1970197519801985199019952005201020152020202502468101214161820222426YearIndividuals

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
69
Matched controls
690
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A98, ,
ICD-O-3
+∞
99.1
69
*
D734, ,
ICD-10 Finland
Cyst of spleen
+∞
99.1
69
*
N02BE01, ,
ATC
paracetamol; systemic, rectal
+∞
81.0
61
*
M01AE01, ,
ATC
ibuprofen; systemic, rectal
+∞
77.3
59
*
J01DB01, ,
ATC
cefalexin; oral
+∞
77.3
59
*
J01CA04, ,
ATC
amoxicillin; systemic
+∞
70.2
55
*
A02BC02, ,
ATC
pantoprazole; systemic
+∞
66.9
53
*
WX110, ,
ICD-O-3
+∞
63.7
51
*
SAA01, ,
ICD-O-3
+∞
59.1
48
*
J01AA02, ,
ATC
doxycycline; systemic
+∞
57.6
47
*
SAA02, ,
ICD-O-3
+∞
53.1
44
*
M03BX02, ,
ATC
tizanidine; oral
+∞
51.7
43
*
J01CE02, ,
ATC
phenoxymethylpenicillin; oral
+∞
51.7
43
*
M01AE02, ,
ATC
naproxen; oral, rectal
+∞
48.9
41
*
R03AC02, ,
ATC
salbutamol; inhalant
+∞
47.5
40
*
M01AB05, ,
ATC
diclofenac; systemic, rectal
+∞
47.5
40
*
SFA20, ,
ICD-O-3
+∞
46.1
39
*
K021, ,
ICD-O-3
+∞
46.1
39
*
EB1SA, ,
ICD-O-3
+∞
44.7
38
*
M01AH05, ,
ATC
etoricoxib; oral
+∞
43.4
37
*
J01FA10, ,
ATC
azithromycin; systemic
+∞
42.0
36
*
GD1AA, ,
ICD-O-3
+∞
39.4
34
*
WX290, ,
ICD-O-3
+∞
39.4
34
*
SFA10, ,
ICD-O-3
+∞
39.4
34
*
J069, ,
ICD-O-3
+∞
38.1
33
*
J01CR02, ,
ATC
amoxicillin and beta-lactamase inhibitor; systemic
+∞
38.1
33
*
EB1AA, ,
ICD-O-3
+∞
36.8
32
*
A02BC05, ,
ATC
esomeprazole; systemic
+∞
36.8
32
*
R01AD09, ,
ATC
mometasone; nasal
+∞
36.8
32
*
H02AB06, ,
ATC
prednisolone; systemic
+∞
34.2
30
*
Z012, ,
ICD-O-3
+∞
33.0
29
*
N02AX02, ,
ATC
tramadol; systemic, rectal
+∞
33.0
29
*
J01DA01, ,
ATC
[U] cefalexin
+∞
33.0
29
*
N02AJ06, ,
ATC
codeine and paracetamol; systemic
+∞
31.7
28
*
D82, ,
ICD-O-3
+∞
31.7
28
*
UJD10, ,
ICD-O-3
+∞
31.7
28
*
E0000UV, ,
ATC
+∞
31.7
28
*
R104, ,
ICD-10 Finland
Other and unspecified abdominal pain
+∞
31.7
28
*
P01AB01, ,
ATC
metronidazole; oral, rectal
+∞
31.7
28
*
WYA05, ,
ICD-O-3
+∞
30.5
27
*
SPAT1256, ,
ICD-O-3
+∞
30.5
27
*
WZC00, ,
ICD-O-3
+∞
30.5
27
*
JN1AE, ,
ICD-O-3
+∞
29.2
26
*
UJF32, ,
ICD-O-3
+∞
29.2
26
*
ZXE10, ,
ICD-O-3
+∞
29.2
26
*
SDA03, ,
ICD-O-3
+∞
29.2
26
*
SAA03, ,
ICD-O-3
+∞
28.0
25
*
ZXD10, ,
ICD-O-3
+∞
28.0
25
*
N02AA59, ,
ATC
codeine, combinations excl. psycholeptics; systemic
+∞
28.0
25
*
EB1HA, ,
ICD-O-3
+∞
26.8
24
*
SDA02, ,
ICD-O-3
+∞
26.8
24
*
SFA30, ,
ICD-O-3
+∞
26.8
24
*
D07AB02, ,
ATC
hydrocortisone butyrate; topical
+∞
26.8
24
*
J01CA08, ,
ATC
pivmecillinam; oral
+∞
26.8
24
*
D07AC01, ,
ATC
betamethasone; topical
+∞
26.8
24
*
KMAK, ,
ICD-O-3
+∞
26.8
24
*
R74, ,
ICD-O-3
+∞
26.8
24
*
SPAT1263, ,
ICD-O-3
+∞
26.8
24
*
A12AX, ,
ATC
Calcium, combinations with vitamin D and/or other drugs
+∞
25.6
23
*
C07AB07, ,
ATC
bisoprolol; oral
+∞
25.6
23
*
R06AX27, ,
ATC
desloratadine; oral
+∞
25.6
23
*
R05FA02, ,
ATC
opium derivatives and expectorants; systemic
+∞
24.4
22
*
M01AE03, ,
ATC
ketoprofen; systemic, rectal
+∞
24.4
22
*
J01MA02, ,
ATC
ciprofloxacin; systemic
+∞
24.4
22
*
M01AC06, ,
ATC
meloxicam; systemic, rectal
+∞
24.4
22
*
G03CA03, ,
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
+∞
24.4
22
*
R01AD12, ,
ATC
fluticasone furoate; nasal
+∞
24.4
22
*
J01FA06, ,
ATC
roxithromycin; oral
+∞
24.4
22
*
S01XA20, ,
ATC
artificial tears and other indifferent preparations; ophthalmic
+∞
23.2
21
*
ZXE00, ,
ICD-O-3
+∞
23.2
21
*
Z871, ,
ICD-O-3
+∞
23.2
21
*
W01, ,
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
+∞
23.2
21
*
SPAT1325, ,
ICD-O-3
+∞
23.2
21
*
-1, ,
ICD-O-3
+∞
22.0
20
*
SPAT1301, ,
ICD-O-3
+∞
22.0
20
*
SPAT1249, ,
ICD-O-3
+∞
22.0
20
*
N06AX11, ,
ATC
mirtazapine; oral
+∞
22.0
20
*
JN3AE, ,
ICD-O-3
+∞
22.0
20
*
S18, ,
ICD-O-3
+∞
22.0
20
*
J01FA09, ,
ATC
clarithromycin; systemic
+∞
22.0
20
*
I10, ,
ICD-O-3
+∞
22.0
20
*
J02AC01, ,
ATC
fluconazole; systemic
+∞
22.0
20
*
R103, ,
ICD-10 Finland
Pain localized to other parts of lower abdomen
+∞
22.0
20
*
WX408, ,
ICD-O-3
+∞
20.9
19
*
R06AE07, ,
ATC
cetirizine; oral
+∞
20.9
19
*
D07AC13, ,
ATC
mometasone; topical
+∞
20.9
19
*
M545, ,
ICD-O-3
+∞
20.9
19
*
LC2BE, ,
ICD-O-3
+∞
20.9
19
*
J010, ,
ICD-O-3
+∞
20.9
19
*
I10, ,
ICD-10 Finland
Essential (primary) hypertension
+∞
19.7
18
*
R01BA52, ,
ATC
pseudoephedrine, combinations; oral
+∞
19.7
18
*
K0364, ,
ICD-O-3
+∞
19.7
18
*
N05BA04, ,
ATC
oxazepam; oral
+∞
19.7
18
*
OAB43, ,
ICD-O-3
+∞
19.7
18
*
SDA04, ,
ICD-O-3
+∞
19.7
18
*
A02BC01, ,
ATC
omeprazole; systemic
+∞
19.7
18
*
M796, ,
ICD-O-3
+∞
19.7
18
*
SDA01, ,
ICD-O-3
+∞
19.7
18
*
SPAT1253, ,
ICD-O-3
+∞
19.7
18
*
WZB00, ,
ICD-O-3
+∞
18.6
17
*
SPAT1310, ,
ICD-O-3
+∞
18.6
17
*
Z718, ,
ICD-10 Finland
Other specified counselling
+∞
18.6
17
*
R01AD58, ,
ATC
fluticasone, combinations; nasal
+∞
18.6
17
*
R101, ,
ICD-10 Finland
Pain localized to upper abdomen
+∞
18.6
17
*
A06AC01, ,
ATC
ispaghula (psylla seeds); oral
+∞
18.6
17
*
R104, ,
ICD-O-3
+∞
18.6
17
*
SDE02, ,
ICD-O-3
+∞
18.6
17
*
FM1EE, ,
ICD-O-3
+∞
18.6
17
*
Z2221, ,
ICD-O-3
+∞
18.6
17
*
O800, ,
ICD-10 Finland
Spontaneous vertex delivery
+∞
17.4
16
*
Z363, ,
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
+∞
17.4
16
*
Z760, ,
ICD-O-3
+∞
17.4
16
*
N05CF01, ,
ATC
zopiclone; oral
+∞
17.4
16
*
R01AD01, ,
ATC
beclometasone; nasal
+∞
17.4
16
*
ZXD05, ,
ICD-O-3
+∞
17.4
16
*
R05, ,
ICD-O-3
+∞
17.4
16
*
A02BC03, ,
ATC
lansoprazole; oral
+∞
17.4
16
*
SPAT1153, ,
ICD-O-3
+∞
17.4
16
*
WX404, ,
ICD-O-3
+∞
17.4
16
*
C10AA01, ,
ATC
simvastatin; oral
+∞
17.4
16
*
WZC30, ,
ICD-O-3
+∞
16.3
15
*
EBA00, ,
ICD-O-3
+∞
16.3
15
*
J01EE02, ,
ATC
sulfadiazine and trimethoprim; systemic
+∞
16.3
15
*
K0382, ,
ICD-O-3
+∞
16.3
15
*
R4110, ,
ICD-O-3
+∞
16.3
15
*
R21, ,
ICD-O-3
+∞
16.3
15
*
R83, ,
ICD-O-3
+∞
16.3
15
*
A03FA01, ,
ATC
metoclopramide; systemic, rectal
+∞
16.3
15
*
ZXA05, ,
ICD-O-3
+∞
16.3
15
*
WW200, ,
ICD-O-3
+∞
16.3
15
*
WZA90, ,
ICD-O-3
+∞
16.3
15
*
R01AD08, ,
ATC
fluticasone; nasal
+∞
16.3
15
*
SCA01, ,
ICD-O-3
+∞
16.3
15
*
SPAT1223, ,
ICD-O-3
+∞
15.1
14
*
TPH04, ,
ICD-O-3
+∞
15.1
14
*
WX402, ,
ICD-O-3
+∞
15.1
14
*
D19, ,
ICD-O-3
+∞
15.1
14
*
R101, ,
ICD-O-3
+∞
15.1
14
*
S01CA01, ,
ATC
dexamethasone and antiinfectives; ophthalmic
+∞
15.1
14
*
J01EA01, ,
ATC
trimethoprim; systemic
+∞
15.1
14
*
WX320, ,
ICD-O-3
+∞
15.1
14
*
SPAT1312, ,
ICD-O-3
+∞
14.0
13
*
MA2HE, ,
ICD-O-3
+∞
14.0
13
*
B01AB05, ,
ATC
enoxaparin; parenteral
+∞
14.0
13
*
H03AA01, ,
ATC
levothyroxine sodium; systemic
+∞
14.0
13
*
M03BC01, ,
ATC
orphenadrine (citrate); systemic
+∞
14.0
13
*
L03, ,
ICD-O-3
+∞
14.0
13
*
C10AA05, ,
ATC
atorvastatin; oral
+∞
14.0
13
*
Z3231, ,
ICD-O-3
+∞
14.0
13
*
W78, ,
ICD-O-3
+∞
14.0
13
*
R074, ,
ICD-10 Finland
Chest pain, unspecified
+∞
14.0
13
*
M255, ,
ICD-O-3
+∞
14.0
13
*
C09CA06, ,
ATC
candesartan; oral
+∞
14.0
13
*
S01GX01, ,
ATC
cromoglicic acid; ophthalmic
+∞
14.0
13
*
SFC01, ,
ICD-O-3
+∞
14.0
13
*
ZXA00, ,
ICD-O-3
+∞
14.0
13
*
L08, ,
ICD-O-3
+∞
14.0
13
*
Z712, ,
ICD-O-3
+∞
14.0
13
*
C03CA01, ,
ATC
furosemide; systemic
+∞
14.0
13
*
N02CC01, ,
ATC
sumatriptan; nasal, systemic, rectal
+∞
14.0
13
*
VALMI, ,
ICD-O-3
+∞
14.0
13
*
F510, ,
ICD-O-3
+∞
12.9
12
*
N06AB04, ,
ATC
citalopram; systemic
+∞
12.9
12
*
L17, ,
ICD-O-3
+∞
12.9
12
*
M54, ,
ICD-O-3
+∞
12.9
12
*
B01AB10, ,
ATC
tinzaparin; parenteral
+∞
12.9
12
*
Z3226, ,
ICD-O-3
+∞
12.9
12
*
Z018, ,
ICD-10 Finland
Other specified special examinations
+∞
12.9
12
*
L309, ,
ICD-O-3
+∞
12.9
12
*
C01DA08, ,
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
+∞
12.9
12
*
M796, ,
ICD-10 Finland
Pain in limb
+∞
12.9
12
*
SPAT1379, ,
ICD-O-3
+∞
11.8
11
*
R53, ,
ICD-O-3
+∞
11.8
11
*
LX1AE, ,
ICD-O-3
+∞
11.8
11
*
C08CA01, ,
ATC
amlodipine; oral
+∞
11.8
11
*
EP1AE, ,
ICD-O-3
+∞
11.8
11
*
C10AA07, ,
ATC
rosuvastatin; oral
+∞
11.8
11
*
M02AA07, ,
ATC
piroxicam; topical
+∞
11.8
11
*
E000001, ,
ATC
+∞
11.8
11
*
R05DA20, ,
ATC
opium alkaloids and derivatives - combinations
+∞
11.8
11
*
X59, ,
ICD-10 Finland
Exposure to unspecified factor
+∞
11.8
11
*
K0365, ,
ICD-O-3
+∞
11.8
11
*
R060, ,
ICD-10 Finland
Dyspnoea
+∞
11.8
11
*
NH3AA, ,
ICD-O-3
+∞
11.8
11
*
MA2AE, ,
ICD-O-3
+∞
11.8
11
*
Z718, ,
ICD-O-3
+∞
11.8
11
*
G01AA10, ,
ATC
clindamycin; vaginal
+∞
10.7
10
*
R03BA05, ,
ATC
fluticasone; inhalant
+∞
10.7
10
*
WX602, ,
ICD-O-3
+∞
10.7
10
*
CJE20, ,
ICD-O-3
+∞
10.7
10
*
SPAT1197, ,
ICD-O-3
+∞
10.7
10
*
R06AX13, ,
ATC
loratadine; oral
+∞
10.7
10
*
SDE03, ,
ICD-O-3
+∞
10.7
10
*
WX700, ,
ICD-O-3
+∞
10.7
10
*
A02BA02, ,
ATC
ranitidine; systemic
+∞
10.7
10
*
MCA10, ,
ICD-O-3
+∞
10.7
10
*
J01AA07, ,
ATC
tetracycline; systemic
+∞
10.7
10
*
JN3AD, ,
ICD-O-3
+∞
10.7
10
*
J02AC02, ,
ATC
itraconazole; systemic
+∞
10.7
10
*
U072, ,
ICD-O-3
+∞
10.7
10
*
D01AC20, ,
ATC
imidazoles/triazoles in combination with corticosteroids; topical
+∞
10.7
10
*
K045, ,
ICD-O-3
+∞
10.7
10
*
A46, ,
ICD-10 Finland
Erysipelas
+∞
10.7
10
*
J05AB01, ,
ATC
aciclovir; systemic
+∞
10.7
10
*
J01DA09, ,
ATC
[U] cefadroxil
+∞
10.7
10
*
SGB10, ,
ICD-O-3
+∞
10.7
10
*
FN1AC, ,
ICD-O-3
+∞
10.7
10
*
SFA40, ,
ICD-O-3
+∞
10.7
10
*
65000, ,
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
+∞
10.7
10
*
SPAT1250, ,
ICD-O-3
+∞
10.7
10
*
J01MA12, ,
ATC
levofloxacin; systemic
+∞
10.7
10
*
SGA01, ,
ICD-O-3
+∞
10.7
10
*
R238, ,
ICD-O-3
+∞
10.7
10
*
N05CF02, ,
ATC
zolpidem; oral
+∞
10.7
10
*
205, ,
Kela drug reimbursment
Chronic hypertension
+∞
9.6
9
*
N02AA05, ,
ATC
oxycodone; systemic
+∞
9.6
9
*
FM1AE, ,
ICD-O-3
+∞
9.6
9
*
ZXE20, ,
ICD-O-3
+∞
9.6
9
*
SPAT1380, ,
ICD-O-3
+∞
9.6
9
*
SPAT1324, ,
ICD-O-3
+∞
9.6
9
*
Z010, ,
ICD-10 Finland
Examination of eyes and vision
+∞
9.6
9
*
C07AA05, ,
ATC
propranolol; systemic
+∞
9.6
9
*
C09AA02, ,
ATC
enalapril; systemic
+∞
9.6
9
*
EBA05, ,
ICD-O-3
+∞
9.6
9
*
M544, ,
ICD-O-3
+∞
9.6
9
*
L15, ,
ICD-O-3
+∞
9.6
9
*
M03BC51, ,
ATC
orphenadrine, combinations; systemic
+∞
9.6
9
*
OAB48, ,
ICD-O-3
+∞
9.6
9
*
JN3BD, ,
ICD-O-3
+∞
9.6
9
*
SPAT1283, ,
ICD-O-3
+∞
9.6
9
*
D07AA02, ,
ATC
hydrocortisone; topical
+∞
9.6
9
*
M01AX17, ,
ATC
nimesulide; oral
+∞
9.6
9
*
SAD01, ,
ICD-O-3
+∞
9.6
9
*
AA1AD, ,
ICD-O-3
+∞
9.6
9
*
I251, ,
ICD-10 Finland
Atherosclerotic heart disease
+∞
9.6
9
*
202, ,
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
+∞
9.6
9
*
R03BA02, ,
ATC
budesonide; inhalant
+∞
9.6
9
*
D07AD01, ,
ATC
clobetasol; topical
+∞
9.6
9
*
SPAT1230, ,
ICD-O-3
+∞
9.6
9
*
OAA65, ,
ICD-O-3
+∞
9.6
9
*
R103, ,
ICD-O-3
+∞
9.6
9
*
J01FA01, ,
ATC
erythromycin; systemic
+∞
9.6
9
*
UKC02, ,
ICD-O-3
+∞
9.6
9
*
TPH07, ,
ICD-O-3
+∞
9.6
9
*
MA2DE, ,
ICD-O-3
+∞
9.6
9
*
R074, ,
ICD-O-3
+∞
9.6
9
*
S29, ,
ICD-O-3
+∞
9.6
9
*
R05FB02, ,
ATC
cough suppressants and expectorants; systemic
+∞
9.6
9
*
N06AB10, ,
ATC
escitalopram; oral
+∞
9.6
9
*
K0510, ,
ICD-O-3
+∞
9.6
9
*
WX307, ,
ICD-O-3
+∞
8.5
8
*
N10, ,
ICD-10 Finland
Acute tubulo-interstitial nephritis
+∞
8.5
8
*
X58, ,
ICD-10 Finland
Exposure to other specified factors
+∞
8.5
8
*
C09CA01, ,
ATC
losartan; oral
+∞
8.5
8
*
K30, ,
ICD-O-3
+∞
8.5
8
*
B02AA02, ,
ATC
tranexamic acid; systemic
+∞
8.5
8
*
JN4AD, ,
ICD-O-3
+∞
8.5
8
*
SFA00, ,
ICD-O-3
+∞
8.5
8
*
A04, ,
ICD-O-3
+∞
8.5
8
*
N05AH04, ,
ATC
quetiapine; oral
+∞
8.5
8
*
U071, ,
ICD-O-3
+∞
8.5
8
*
EBA10, ,
ICD-O-3
+∞
8.5
8
*
L02, ,
ICD-O-3
+∞
8.5
8
*
K210, ,
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
+∞
8.5
8
*
I48, ,
ICD-10 Finland
Atrial fibrillation and flutter
+∞
8.5
8
*
L16, ,
ICD-O-3
+∞
8.5
8
*
Z301, ,
ICD-O-3
+∞
8.5
8
*
S525, ,
ICD-10 Finland
Fracture of lower end of radius
+∞
8.5
8
*
C03DA01, ,
ATC
spironolactone; oral
+∞
8.5
8
*
G04CA02, ,
ATC
tamsulosin; oral
+∞
8.5
8
*
JMA10, ,
ICD-O-3
+∞
8.5
8
*
J05AB11, ,
ATC
valaciclovir; oral
+∞
8.5
8
*
Z017, ,
ICD-O-3
+∞
8.5
8
*
NG1AA, ,
ICD-O-3
+∞
8.5
8
*
N05BA01, ,
ATC
diazepam; systemic, rectal
+∞
8.5
8
*
J20, ,
ICD-O-3
+∞
8.5
8
*
A03, ,
ICD-O-3
+∞
8.5
8
*
M171, ,
ICD-10 Finland
Other primary gonarthrosis
+∞
8.5
8
*
XX3DW, ,
ICD-O-3
+∞
8.5
8
*
C09AA05, ,
ATC
ramipril; oral
+∞
8.5
8
*
KH1AD, ,
ICD-O-3
+∞
8.5
8
*
PH2AE, ,
ICD-O-3
+∞
8.5
8
*
L13, ,
ICD-O-3
+∞
8.5
8
*
SPAT1254, ,
ICD-O-3
+∞
8.5
8
*
K30, ,
ICD-10 Finland
Functional dyspepsia
+∞
8.5
8
*
R509, ,
ICD-10 Finland
Fever, unspecified
+∞
8.5
8
*
R060, ,
ICD-O-3
+∞
8.5
8
*
C07AB02, ,
ATC
metoprolol; systemic
+∞
8.5
8
*
OAA67, ,
ICD-O-3
+∞
7.4
7
*
SPAT1222, ,
ICD-O-3
+∞
7.4
7
*
JKA21, ,
ICD-O-3
+∞
7.4
7
*
L01, ,
ICD-O-3
+∞
7.4
7
*
I872, ,
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
+∞
7.4
7
*
SPAT1317, ,
ICD-O-3
+∞
7.4
7
*
M751, ,
ICD-10 Finland
Rotator cuff syndrome
+∞
7.4
7
*
6500B, ,
ICD-9 Finland
Delivery in a completely normal case[PARTUS SINE COMPLICATIONE]
+∞
7.4
7
*
SGA04, ,
ICD-O-3
+∞
7.4
7
*
Z392, ,
ICD-O-3
+∞
7.4
7
*
ZXA10, ,
ICD-O-3
+∞
7.4
7
*
JN1CG, ,
ICD-O-3
+∞
7.4
7
*
W22, ,
ICD-10 Finland
Striking against or struck by other object(s)
+∞
7.4
7
*
SGA02, ,
ICD-O-3
+∞
7.4
7
*
N920, ,
ICD-10 Finland
Excessive and frequent menstruation with regular cycle
+∞
7.4
7
*
W90, ,
ICD-O-3
+∞
7.4
7
*
J01FF01, ,
ATC
clindamycin; systemic
+∞
7.4
7
*
K0532, ,
ICD-O-3
+∞
7.4
7
*
SCA02, ,
ICD-O-3
+∞
7.4
7
*
J01DA06, ,
ATC
[U] cefuroxime
+∞
7.4
7
*
K020, ,
ICD-O-3
+∞
7.4
7
*
JN1DG, ,
ICD-O-3
+∞
7.4
7
*
Z024, ,
ICD-O-3
+∞
7.4
7
*
R03DC03, ,
ATC
montelukast; oral
+∞
7.4
7
*
K02, ,
ICD-O-3
+∞
7.4
7
*
EB4VA, ,
ICD-O-3
+∞
7.4
7
*
203, ,
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
+∞
7.4
7
*
TQW40, ,
ICD-O-3
+∞
7.4
7
*
G01AF01, ,
ATC
metronidazole; vaginal
+∞
7.4
7
*
ZXD20, ,
ICD-O-3
+∞
7.4
7
*
Z039, ,
ICD-10 Finland
Observation for suspected disease or condition, unspecified
+∞
7.4
7
*
R03AK07, ,
ATC
formoterol and budesonide; inhalant
+∞
7.4
7
*
OAA11, ,
ICD-O-3
+∞
7.4
7
*
R06AX22, ,
ATC
ebastine; oral
+∞
7.4
7
*
H251, ,
ICD-10 Finland
Senile nuclear cataract
+∞
7.4
7
*
SPAT1216, ,
ICD-O-3
+∞
7.4
7
*
SPAT1308, ,
ICD-O-3
+∞
7.4
7
*
ND2AA, ,
ICD-O-3
+∞
7.4
7
*
Z015, ,
ICD-10 Finland
Diagnostic skin and sensitization tests
+∞
7.4
7
*
Z961, ,
ICD-10 Finland
Presence of intraocular lens
+∞
7.4
7
*
R06AE09, ,
ATC
levocetirizine; oral
+∞
7.4
7
*
NK6QA, ,
ICD-O-3
+∞
7.4
7
*
R5180, ,
ICD-10 Finland
Headache
+∞
7.4
7
*
ZX120, ,
ICD-O-3
+∞
7.4
7
*
207, ,
Kela drug reimbursment
Chronic arrhythmias
+∞
7.4
7
*
J01AA04, ,
ATC
lymecycline; systemic
+∞
7.4
7
*
D01, ,
ICD-O-3
+∞
7.4
7
*
G560, ,
ICD-O-3
+∞
7.4
7
*
N03AX16, ,
ATC
[U] pregabalin
+∞
7.4
7
*
M01AX05, ,
ATC
glucosamine; oral
+∞
7.4
7
*
Z048, ,
ICD-10 Finland
Examination and observation for other specified reasons
+∞
7.4
7
*
Z014, ,
ICD-O-3
+∞
6.3
6
*
R01AD59, ,
ATC
mometasone, combinations; nasal
+∞
6.3
6
*
N390, ,
ICD-10 Finland
Urinary tract infection, site not specified
+∞
6.3
6
*
L05, ,
ICD-O-3
+∞
6.3
6
*
M545, ,
ICD-10 Finland
Low back pain
+∞
6.3
6
*
LAF11, ,
ICD-O-3
+∞
6.3
6
*
SAB01, ,
ICD-O-3
+∞
6.3
6
*
WZC20, ,
ICD-O-3
+∞
6.3
6
*
C01DA02, ,
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
+∞
6.3
6
*
M02AA10, ,
ATC
ketoprofen; topical
+∞
6.3
6
*
NGB20, ,
ICD-O-3
+∞
6.3
6
*
206, ,
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
+∞
6.3
6
*
A07EC02, ,
ATC
mesalazine; oral, rectal
+∞
6.3
6
*
G03DB01, ,
ATC
dydrogesterone; oral
+∞
6.3
6
*
D07CC01, ,
ATC
betamethasone and antibiotics; topical
+∞
6.3
6
*
XMA22, ,
ICD-O-3
+∞
6.3
6
*
HA1AE, ,
ICD-O-3
+∞
6.3
6
*
N02CC03, ,
ATC
zolmitriptan; nasal, oral
+∞
6.3
6
*
WX302, ,
ICD-O-3
+∞
6.3
6
*
C05AA08, ,
ATC
fluocortolone; rectal, topical
+∞
6.3
6
*
SPAT1097, ,
ICD-O-3
+∞
6.3
6
*
L309, ,
ICD-10 Finland
Dermatitis, unspecified
+∞
6.3
6
*
FB1BD, ,
ICD-O-3
+∞
6.3
6
*
G473, ,
ICD-10 Finland
Sleep apnoea
+∞
6.3
6
*
C10AX09, ,
ATC
ezetimibe; oral
+∞
6.3
6
*
M751, ,
ICD-O-3
+∞
6.3
6
*
A09, ,
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
+∞
6.3
6
*
ULA02, ,
ICD-O-3
+∞
6.3
6
*
OAB95, ,
ICD-O-3
+∞
6.3
6
*
JMA11, ,
ICD-O-3
+∞
6.3
6
*
R229, ,
ICD-O-3
+∞
6.3
6
*
NA3BG, ,
ICD-O-3
+∞
6.3
6
*
NB1AA, ,
ICD-O-3
+∞
6.3
6
*
F419, ,
ICD-10 Finland
Anxiety disorder, unspecified
+∞
6.3
6
*
JMW97, ,
ICD-O-3
+∞
6.3
6
*
LC2AE, ,
ICD-O-3
+∞
6.3
6
*
M04AA01, ,
ATC
allopurinol; systemic
+∞
6.3
6
*
N03AX12, ,
ATC
[U] gabapentin; oral
+∞
6.3
6
*
C08CA13, ,
ATC
lercanidipine; oral
+∞
6.3
6
*
290, ,
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
+∞
6.3
6
*
K041, ,
ICD-O-3
+∞
6.3
6
*
M01AG02, ,
ATC
tolfenamic acid; oral, rectal
+∞
6.3
6
*
A06AD11, ,
ATC
lactulose; oral
+∞
6.3
6
*
M01AH01, ,
ATC
celecoxib; oral
+∞
6.3
6
*
WX002, ,
ICD-O-3
+∞
6.3
6
*
MAX99, ,
ICD-O-3
+∞
6.3
6
*
Z348, ,
ICD-O-3
+∞
6.3
6
*
I639, ,
ICD-10 Finland
Cerebral infarction, unspecified
+∞
6.3
6
*
G03FB08, ,
ATC
dydrogesterone and estrogen; systemic
+∞
6.3
6
*
N01, ,
ICD-O-3
+∞
6.3
6
*
SHB00, ,
ICD-O-3
+∞
6.3
6
*
F3210, ,
ICD-10 Finland
Moderate depressive episode without somatic syndrome
+∞
6.3
6
*
M511, ,
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
+∞
6.3
6
*
R02, ,
ICD-O-3
+∞
6.3
6
*
MA2JE, ,
ICD-O-3
+∞
6.3
6
*
SGA03, ,
ICD-O-3
+∞
6.3
6
*
R298, ,
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
+∞
6.3
6
*
R03AC03, ,
ATC
terbutaline; inhalant
+∞
6.3
6
*
C03EA01, ,
ATC
hydrochlorothiazide and potassium-sparing agents; oral
+∞
6.3
6
*
K802, ,
ICD-10 Finland
Calculus of gallbladder without cholecystitis
+∞
6.3
6
*
H438, ,
ICD-10 Finland
Other disorders of vitreous body
+∞
6.3
6
*
A97, ,
ICD-O-3
+∞
6.3
6
*
R03AK06, ,
ATC
salmeterol and fluticasone; inhalant
+∞
6.3
6
*
SPAT1262, ,
ICD-O-3
+∞
6.3
6
*
M255, ,
ICD-10 Finland
Pain in joint
+∞
6.3
6
*
Z004, ,
ICD-10 Finland
General psychiatric examination, not elsewhere classified
+∞
6.3
6
*
Z014, ,
ICD-10 Finland
Gynaecological examination (general)(routine)
+∞
6.3
6
*
H02AB04, ,
ATC
methylprednisolone; systemic
+∞
6.3
6
*
J189, ,
ICD-10 Finland
Pneumonia, unspecified
+∞
6.3
6
*
N30, ,
ICD-O-3
+∞
6.3
6
*
G02BA03, ,
ATC
plastic IUD with progestogen
+∞
6.3
6
*
O8210, ,
ICD-10 Finland
Delivery by emergency caesarean section
+∞
6.3
6
*
R876, ,
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
+∞
6.3
6
*
L90, ,
ICD-O-3
+∞
6.3
6
*
SPAT1033, ,
ICD-O-3
+∞
6.3
6
*
Z348, ,
ICD-10 Finland
Supervision of other normal pregnancy
+∞
6.3
6
*
WX400, ,
ICD-O-3
+∞
6.3
6
*
N06AB06, ,
ATC
sertraline; oral
+∞
6.3
6
*
K573, ,
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
+∞
6.3
6
*
G560, ,
ICD-10 Finland
Carpal tunnel syndrome
+∞
6.3
6
*
AA1BG, ,
ICD-O-3
+∞
6.3
6
*
K040, ,
ICD-O-3
+∞
6.3
6
*
351, ,
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
+∞
6.3
6
*
Z039, ,
ICD-O-3
+∞
6.3
6
*
N390, ,
ICD-O-3
+∞
6.3
6
*
D07BB04, ,
ATC
hydrocortisone butyrate and antiseptics; topical
+∞
6.3
6
*
L04AX03, ,
ATC
methotrexate; systemic
+∞
6.3
6
*
D01BA02, ,
ATC
terbinafine; oral
+∞
6.3
6
*
SPAT1260, ,
ICD-O-3
+∞
6.3
6
*
N06AX16, ,
ATC
venlafaxine; oral
+∞
6.3
6
*
UJF30, ,
ICD-O-3
+∞
6.3
6
*
A48, ,
ICD-O-3
+∞
6.3
6
*
P01BA02, ,
ATC
hydroxychloroquine; oral
+∞
6.3
6
*
A07EC01, ,
ATC
sulfasalazine; oral, rectal
+∞
6.3
6
*
E780, ,
ICD-O-3
+∞
6.3
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
21
78
3.43
4.79
1.3
1.2
—
—
—
0
0
32
164
2.77
4.10
1.7
1.9
—
—
—
0
0
14
47
3.48
3.66
6.4
7.3
104.93
103.26
mmol/l
0.79
14
47
17
66
3.09
3.54
1.2
3.0
30.53
29.55
s
0.14
17
66
10
30
3.72
2.73
5.6
11.6
—
—
—
0
0
9
25
3.98
2.68
4.8
23.5
—
—
—
0
0
51
375
2.38
2.56
5.1
4.0
—
37.25
—
0
8
54
414
2.40
2.35
5.0
4.1
—
—
—
0
0
14
62
2.58
2.25
1.3
1.5
—
—
—
0
0
24
138
2.13
2.16
1.9
3.0
322.21
335.04
umol/l
0.25
19
129
14
64
2.49
2.11
1.3
1.4
—
—
—
0
0
8
26
3.34
2.09
1.6
1.3
—
—
—
0
0
33
218
1.98
2.03
9.2
8.4
1.19
1.22
mmol/l
0.92
28
204
9
33
2.98
2.02
3.9
3.2
—
—
—
0
0
26
160
2.00
1.93
3.5
2.5
—
—
—
0
0
38
267
1.94
1.93
7.9
6.7
—
—
—
0
0
23
136
2.04
1.90
1.8
1.7
—
—
—
0
0
31
204
1.94
1.90
15.9
15.3
1.22
1.29
inr
—
10
64
33
223
1.92
1.86
8.7
5.5
36.87
36.44
g/l
0.19
33
211
8
30
2.88
1.79
1.6
1.3
—
—
—
0
0
8
30
2.88
1.79
1.6
1.3
—
—
—
0
0
8
30
2.88
1.79
1.6
1.3
—
—
—
0
0
8
30
2.88
1.79
1.6
1.3
—
—
—
0
0
20
116
2.02
1.73
6.0
4.5
—
—
—
0
0
34
239
1.83
1.65
12.1
8.9
1.20
1.22
mmol/l
0.57
27
212
6
20
3.18
1.62
6.3
13.7
94.65
91.35
%
—
6
20
6
20
3.18
1.62
5.7
2.6
0.67
0.72
%
—
6
20
24
152
1.89
1.60
2.8
2.6
—
—
—
0
0
15
80
2.12
1.60
4.0
5.0
4.07
6.32
umol/l
1.12
15
69
16
88
2.07
1.58
1.5
1.5
1748.57
1010.91
titre
—
7
22
6
21
3.03
1.54
9.2
35.1
—
—
—
0
0
6
22
2.89
1.47
5.7
2.5
1.42
2.18
%
—
6
22
69
652
+∞
1.39
29.6
17.9
260.36
256.32
e9/l
0.18
69
640
5
17
3.09
1.38
7.8
4.8
—
—
—
0
0
8
152
0.46
1.35
4.2
3.5
3.01
11.36
mg/mmol
—
8
95
6
24
2.64
1.33
1.5
1.1
—
—
—
0
0
6
24
2.64
1.33
10.2
2.9
23.77
23.93
mmol/l
—
6
24
9
44
2.20
1.33
1.4
1.1
—
—
—
0
0
8
35
2.45
1.32
1.1
1.2
—
—
—
0
0
17
102
1.88
1.31
1.9
1.7
—
—
—
0
0
5
19
2.75
1.24
2.2
1.3
9.64
13.77
ug/l
—
5
19
69
655
+∞
1.19
29.8
17.9
133.06
136.04
g/l
1.20
69
647
69
655
+∞
1.19
29.6
17.8
6.80
6.74
e9/l
0.09
69
641
69
654
+∞
1.18
29.4
17.7
91.56
90.71
fl
0.88
69
647
69
654
+∞
1.18
29.7
17.8
4.41
4.51
e12/l
1.30
69
641
69
654
+∞
1.18
29.4
17.7
30.46
30.24
pg
0.62
69
647
5
20
2.61
1.17
2.8
1.5
—
—
—
0
0
28
203
1.64
1.13
3.6
3.3
10.44
49.54
e6/l
1.21
22
141
14
83
1.86
1.12
1.6
1.5
—
—
—
0
0
5
21
2.48
1.11
2.2
1.4
—
—
—
0
0
14
85
1.81
1.04
1.9
2.7
—
—
—
0
0
7
35
2.11
1.03
6.9
7.5
1.34
1.34
mmol/l
—
7
35
9
50
1.92
1.01
9.8
4.8
—
—
—
0
0
0
30
0.00
1.00
0.0
1.0
—
—
—
0
0
6
27
2.33
0.96
11.0
3.6
119.83
135.78
g/l
—
6
27
36
291
1.50
0.85
5.9
4.1
0.00
0.00
estimate
—
6
56
20
143
1.56
0.82
2.1
1.4
2.23
2.32
g/l
0.12
13
87
36
293
1.48
0.81
4.6
3.0
0.00
0.00
estimate
—
6
60
9
143
0.57
0.81
3.4
2.9
3268.63
79.26
mg/l
—
9
93
32
255
1.48
0.80
14.2
8.0
0.00
0.00
e9/l
-0.00
26
207
18
127
1.56
0.78
4.9
2.9
—
—
—
0
0
5
23
2.26
0.78
1.6
1.2
—
—
—
0
0
11
68
1.73
0.77
2.3
2.0
337.91
395.21
nmol/l
0.46
11
63
58
524
1.67
0.77
22.6
14.5
14.15
14.33
%
0.13
58
519
5
24
2.17
0.76
2.6
7.3
—
—
—
0
0
36
296
1.45
0.75
4.6
3.0
0.00
0.00
estimate
—
6
53
5
29
1.78
0.65
1.4
1.5
—
—
—
0
0
8
49
1.71
0.65
4.3
2.5
—
—
—
0
0
5
30
1.72
0.62
2.2
8.1
23.38
24.33
mmol/l
—
5
30
20
155
1.41
0.55
1.5
1.4
0.53
1.10
u/ml
—
7
46
25
204
1.35
0.51
2.2
1.8
103.42
96.27
pmol/l
0.58
15
110
7
48
1.51
0.48
1.4
2.5
3.49
4.08
e9/l
—
7
43
7
48
1.51
0.48
1.1
1.5
—
—
—
0
0
8
57
1.46
0.44
1.5
1.5
—
—
—
0
0
19
152
1.35
0.43
2.1
2.0
125.79
154.57
u/l
0.27
19
143
22
182
1.31
0.40
2.1
1.5
—
—
—
0
0
0
19
0.00
0.39
0.0
1.5
—
—
—
0
0
5
75
0.64
0.38
1.0
1.7
—
—
—
0
0
19
155
1.31
0.38
6.2
3.2
0.00
0.00
estimate
—
5
58
12
91
1.39
0.37
3.0
2.9
219.86
112.95
ng/l
—
7
61
6
45
1.36
0.35
7.7
4.4
62.17
75.35
ng/l
—
6
40
7
56
1.28
0.30
1.3
1.2
—
—
—
0
0
41
377
1.22
0.28
3.7
3.2
—
—
—
0
0
9
73
1.27
0.27
1.3
1.2
—
—
—
0
0
9
74
1.25
0.26
1.4
1.3
—
—
—
0
0
20
172
1.23
0.26
3.7
2.7
—
—
—
0
0
16
135
1.24
0.24
3.6
3.7
—
—
—
0
0
5
40
1.27
0.23
5.8
3.7
4.75
4.54
pmol/l
—
5
34
14
117
1.25
0.23
1.4
1.3
167.48
20.49
iu/ml
—
5
41
21
184
1.20
0.22
5.1
3.1
76.32
21.86
ng/l
0.60
16
109
5
41
1.24
0.22
1.2
1.4
—
—
—
0
0
5
42
1.21
0.22
1.6
1.2
—
—
—
0
0
5
42
1.21
0.22
2.2
6.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.6
—
7.97
—
0
11
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
9
82
1.11
0.15
1.6
1.6
—
—
—
0
0
27
251
1.12
0.13
2.5
2.0
—
—
—
0
0
15
166
0.88
0.11
2.7
2.7
6.40
8.05
mmol/l
0.78
15
144
5
45
1.12
0.10
3.0
1.9
—
—
—
0
0
12
113
1.07
0.02
3.9
3.9
2.05
1.77
ug/l
0.16
12
102
18
185
0.96
0.00
2.3
2.2
—
—
—
0
0
22
225
0.97
0.00
1.8
2.5
—
—
—
0
0
15
155
0.96
0.00
5.1
6.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
3.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
5.6
—
2.38
—
0
8
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
7
77
0.90
-0.00
1.4
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
69.86
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
10.80
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
46.03
—
0
6
0
6
0.00
-0.00
0.0
2.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
6.68
—
0
5
0
6
0.00
-0.00
0.0
1.8
—
0.79
—
0
6
0
6
0.00
-0.00
0.0
1.8
—
1.50
—
0
6
0
5
0.00
-0.00
0.0
10.2
—
0.69
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
239.11
—
0
9

Mortality – FinRegistry

Association

Association between endpoint D3_CYSTSPLEEN and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have D3_CYSTSPLEEN.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: D3_CYSTSPLEEN – Cyst of spleen

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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