Cyst of spleen

D3_CYSTSPLEEN

splenic disease: A disease involving the spleen.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D73.4 Cause of death: ICD-10 — D73.4 2 out of 7 registries used, show all original rules.	79
4. Check minimum number of events None	79
5. Include endpoints None	79
6. Filter based on genotype QC (FinnGen only)	70

Control definitions (FinnGen only)

Control exclude: D3_BLOODOTHER

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: D73
Name in latin: Cysta lienis

NAME	D3_CYSTSPLEEN
CONTROL_EXCLUDE	D3_BLOODOTHER
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D734
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D734
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Cyst of spleen based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	480	271	208
Only index persons	434	248	186
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	41.06	42.38	39.37
Only index persons	43.35	44.73	41.52

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	70	48	22
Unadjusted period prevalence (%)	0.01	0.02	0.01
Median age at first event (years)	46.17	46.12	46.29

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
72: Matched controls
720

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D73.4

ICD-10 Finland

Cyst of spleen

+∞

101.6

JN1AE

NOMESCO Finland

Ultrasound examination of upper part of abdomen

7.9

13.2

JN3AE

NOMESCO Finland

Abdominal ultrasound examination

5.3

7.8

JMA10

NOMESCO Finland

Transabdominal total splenectomy

88.9

7.6

JMA11

NOMESCO Finland

Laparoscopic total splenectomy

+∞

7.4

JMW97

NOMESCO Finland

Other laparoscopic operation on spleen

+∞

6.3

R10.1

ICD-10 Finland

Pain localized to upper abdomen

3.7

6.2

JN1AE, ,

SPAT

10.6

6.0

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(40768797) Stomach Pathology biopsy report

3.08

4.10

1.5

1.2

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

189

2.66

3.98

1.8

2.0

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

3.06

3.52

7.9

9.4

104.12

103.94

mmol/l

0.07

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

157

2.42

3.14

3.7

2.1

3.19

2.42

mg/l

2.31

138

(3026389) Candida sp identified in Specimen by Organism specific culture

7.15

2.92

1.7

1.2

—

(3037467) Urinalysis macro (dipstick) panel - Urine

453

2.67

2.70

5.3

4.4

—

(3031040) Bacteria [#/volume] in Urine by Automated count

421

2.49

2.66

5.4

4.3

—

36.22

—

(3029937) Albumin [Presence] in Urine by Test strip

195

2.15

2.53

4.8

3.3

0.00

estimate

—

(3019060) Gas panel - Arterial blood

3.66

2.49

4.8

22.1

—

(3020891) Body temperature

3.96

2.44

9.8

4.5

36.94

36.91

°c

—

(3026493) Urate [Moles/volume] in Serum or Plasma

156

2.17

2.42

2.1

3.1

325.18

336.42

umol/l

0.24

147

(3018095) Leukocytes [#/volume] in Urine

242

2.09

2.40

3.5

3.7

23.24

62.62

e6/l

0.55

165

(3026008) Bacteria identified in Urine by Culture

182

2.11

2.37

3.7

2.6

—

(3018677) aPTT in Platelet poor plasma by Coagulation assay

2.44

2.36

1.4

2.8

27.88

29.24

0.68

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

2.72

2.35

2.8

3.4

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.40

2.30

1.2

1.5

—

(3035350) Ketones [Presence] in Urine by Test strip

360

2.13

2.29

4.6

3.3

0.00

22.56

estimate

0.49

(3023368) Bacteria identified in Blood by Culture

143

2.15

2.28

6.0

4.5

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

3.28

2.24

2.1

1.7

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

385

2.11

2.16

9.3

8.8

4.14

4.25

e9/l

0.13

342

(36304419) Bacteria [Presence] in Urine

171

2.04

2.13

2.6

2.8

—

estimate

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

316

2.01

2.13

3.5

2.9

—

estimate

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

215

1.99

2.10

3.3

3.1

—

(3021601) Nitrite [Presence] in Urine by Test strip

357

2.03

2.08

4.7

3.2

0.00

estimate

-0.00

(40760892) CBC W Ordered Manual Differential panel - Blood

173

2.01

2.06

5.6

5.0

—

(3000991) Gas panel - Venous blood

2.70

2.04

6.0

13.3

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

2.97

2.01

4.8

5.2

22.82

24.66

mmol/l

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

2.57

2.00

1.3

1.2

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

668

+∞

1.98

27.5

16.7

75.43

73.12

umol/l

0.29

657

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

283

1.93

1.97

12.3

9.3

1.19

1.21

mmol/l

0.95

248

(3009261) Glucose [Presence] in Urine by Test strip

363

1.97

1.92

4.8

3.3

0.00

estimate

-0.00

(3032080) INR in Blood by Coagulation assay

239

1.90

14.7

15.0

1.26

1.22

inr

0.20

195

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

2.97

1.85

7.0

3.9

61.20

53.39

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

4.39

1.85

1.2

13.32

5.12

pmol/l

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

251

1.87

1.81

11.2

9.1

1.19

1.22

mmol/l

1.09

236

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

271

1.85

1.77

5.1

3.1

0.00

0.02

estimate

—

(42870588) Differential panel, method unspecified - Blood

208

1.86

1.74

6.5

6.2

—

(3019150) Specific gravity of Urine by Refractometry

150

1.90

1.66

6.0

3.2

1.02

kg/l

0.34

(3030467) Casts [#/volume] in Urine by Automated count

179

1.81

1.54

2.8

0.19

0.34

e6/l

0.49

124

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

224

1.77

1.53

4.1

4.2

40.56

27.77

u/l

0.38

215

(3022145) Colonoscopy Study observation

2.11

1.52

1.4

1.5

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

2.66

1.49

1.9

1.6

61.18

49.22

ug/l

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

3.28

1.46

2.2

1.6

1.04

1.20

g/l

—

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

1.94

1.43

1.6

1.5

1.38

1.35

0.07

(3002582) Erythrocytes [#/volume] in Urine

211

1.72

1.38

3.1

3.0

15.64

27.13

e6/l

0.58

159

(3017732) Neutrophils [#/volume] in Blood

1.94

1.31

3.1

3.5

3.38

4.37

e9/l

1.53

(3007164) IgA [Mass/volume] in Serum or Plasma

178

1.72

1.31

2.2

1.4

2.29

2.27

g/l

0.03

109

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

2.37

1.29

1.8

1.6

—

(3016879) Cocaine [Presence] in Urine

2.37

1.29

1.6

1.8

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

111

1.83

1.27

2.4

2.8

1.71

0.56

e6/l

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

163

1.71

1.23

1.8

1.7

—

(3019832) Treponema pallidum Ab [Presence] in Serum

121

1.77

1.21

2.1

1.8

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

2.42

1.21

8.2

2.7

0.67

0.65

—

(3015736) pH of Urine

283

1.63

1.21

4.8

3.0

6.30

6.15

0.47

154

(3000764) Benzodiazepines [Presence] in Urine

2.12

1.16

1.6

1.7

—

(3025941) Bacteria identified in Stool by Culture

2.12

1.16

1.1

1.2

—

(3028300) Cannabinoids [Presence] in Urine

2.12

1.16

1.6

1.7

—

(3027008) Opiates [Presence] in Urine

2.12

1.16

1.6

1.7

—

(3003327) Ova and parasites identified in Stool by Light microscopy

2.47

1.16

2.7

1.5

—

(3002385) Erythrocyte [DistWidth] in Red Blood Cells

547

1.96

1.14

26.7

17.5

13.84

13.42

1.63

542

(3027944) Amphetamines [Presence] in Urine

2.07

1.13

1.6

1.7

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

194

1.63

1.11

1.5

1.4

0.54

1.71

u/ml

—

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

1.82

1.11

4.3

5.3

4.13

5.28

umol/l

1.06

(3021589) Normoblasts [#/volume] in Blood

289

1.58

1.07

17.9

9.5

0.00

e9/l

0.50

232

(3014111) Lactate [Moles/volume] in Serum or Plasma

2.04

1.07

6.6

10.6

1.50

1.28

mmol/l

—

(40764999) Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)/1.73 sq M

604

2.11

1.06

19.4

12.5

86.69

87.04

ml/min/173m2

0.04

552

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

262

1.56

1.04

2.4

1.9

103.78

96.38

pmol/l

0.41

140

(40761536) Microorganisms panel - Urine sediment

1.99

1.02

3.6

2.6

—

(3007461) Platelets [#/volume] in Blood

691

+∞

1.00

36.7

21.5

261.00

256.53

e9/l

0.22

680

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

0.00

1.00

0.0

4.5

—

96.07

—

(3024731) MCV [Entitic mean volume] in Red Blood Cells

692

+∞

1.00

36.4

21.4

91.46

90.74

0.79

686

(3009542) Hematocrit [Volume Fraction] of Blood by calculation

692

+∞

1.00

37.0

22.0

39.88

40.89

1.54

686

(3026361) Erythrocytes [#/volume] in Blood

692

+∞

1.00

36.6

21.5

4.40

4.53

e12/l

1.76

679

(3010813) Leukocytes [#/volume] in Blood

692

+∞

1.00

36.7

21.5

6.87

6.76

e9/l

0.16

679

(3035941) MCH [Entitic mass]

692

+∞

1.00

36.4

21.4

30.40

30.26

0.37

686

(3036481) Cortisol [Moles/volume] in Serum or Plasma

1.81

0.99

2.2

2.1

355.54

385.99

nmol/l

0.25

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.99

0.97

1.0

1.4

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

2.33

0.96

8.2

2.7

1.28

2.06

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

2.33

0.96

10.2

2.9

23.77

24.07

mmol/l

—

(3037522) Nuclear Ab [Titer] in Serum

104

1.69

0.94

1.6

1.5

2480.00

1006.67

titre

—

(3011288) Drugs identified in Urine by Screen method Nominal

2.16

0.91

2.0

1.8

—

(3014007) Fractional oxyhemoglobin in Arterial blood

2.09

0.89

10.0

16.8

95.15

91.12

—

(3018418) pH of Serum or Plasma

177

1.53

0.86

7.7

3.3

7.38

7.40

0.83

121

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

160

1.54

0.84

2.4

2.3

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

160

1.54

0.84

5.5

3.1

1396.23

856.14

ng/l

0.44

134

(3048929) Epstein Barr virus Ab [Presence] in Serum

1.89

0.81

1.5

1.2

—

(3042936) Bacteria identified in Isolate by Culture

100

1.63

0.81

2.9

2.7

—

(3000963) Hemoglobin [Mass/volume] in Blood

693

+∞

0.79

37.3

21.6

132.40

136.19

g/l

1.62

686

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

1.76

0.78

1.9

1.7

—

(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay

2.26

0.78

1.0

5.0

3.40

3.47

g/l

—

(3041096) Erythrocytes [Presence] in Urine by Automated

209

1.47

0.76

3.7

2.8

0.00

estimate

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

2.16

0.76

1.4

1.3

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

128

1.54

0.75

2.2

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

2.07

0.74

2.6

1.9

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

2.07

0.74

1.8

1.9

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

2.07

0.74

2.8

1.6

—

5.36

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

183

1.47

0.73

2.0

2.1

116.42

134.86

u/l

0.23

174

(3022313) Gas panel - Capillary blood

1.84

0.67

3.0

6.8

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

1.53

0.62

1.6

3.0

1.08

1.81

e6/l

—

(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.61

0.0

3.3

—

0.80

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.61

0.0

3.3

—

0.00

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.57

0.61

5.1

5.6

—

(3001334) Neutrophil cytoplasmic Ab [Units/volume] in Serum

0.00

0.60

0.0

1.4

—

(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum

0.00

0.60

0.0

1.0

—

12.04

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

1.83

0.60

1.5

1.8

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.54

0.53

3.3

11.8

23.65

25.14

mmol/l

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

102

1.46

0.52

2.9

1.6

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

102

1.46

0.52

3.7

4.5

0.81

0.82

mmol/l

0.14

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

120

1.43

0.52

1.6

2.0

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

473

1.36

0.49

4.1

3.5

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

105

1.41

0.45

1.7

1.5

—

(40768443) Skin Pathology biopsy report

1.66

0.44

1.2

1.1

—

(3001019) Free T4 and TSH panel - Serum or Plasma

1.55

0.42

1.4

1.5

—

(3023420) DNA double strand Ab [Units/volume] in Serum

1.55

0.42

2.8

1.6

—

11.04

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.37

0.42

1.1

1.5

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

0.41

0.0

1.2

—

(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.41

0.0

1.5

—

5.20

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.41

0.0

1.2

—

(36660697) Celiac disease serology panel - Serum

1.37

0.39

1.3

1.2

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

0.00

0.39

0.0

1.5

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.39

0.0

3.4

—

0.00

—

(3000492) Spirometry study

1.35

0.39

1.3

1.5

—

(3003694) ABO and Rh group [Type] in Blood

213

1.27

0.36

2.1

1.6

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

147

1.30

0.35

1.3

167.48

20.89

iu/ml

—

(4035726) Immunohistochemistry procedure

1.36

0.35

1.7

1.2

—

(3002256) Pathology report gross observation

1.38

0.34

1.5

1.2

—

(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma

1.41

0.33

7.3

4.5

67.97

78.50

ng/l

—

(3050129) First trimester maternal screen panel - Serum or Plasma

1.41

0.33

1.9

1.4

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

208

1.23

0.29

5.5

3.3

29.84

21.51

ng/l

0.56

122

(3044640) Blood type and Crossmatch panel - Blood

218

1.22

0.29

2.6

2.3

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.31

0.27

2.2

1.8

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.25

0.26

3.6

1.5

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

147

0.78

0.26

1.2

1.6

—

(3000494) Fungus identified in Specimen by Culture

0.74

0.24

1.1

1.6

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.27

0.23

3.8

1.6

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

165

1.21

0.22

1.7

1.6

—

(3023410) Appearance of Cerebral spinal fluid

0.00

0.21

0.0

1.0

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.8

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.21

0.0

1.2

—

(3012110) Lysozyme [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.8

—

9.14

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.21

0.0

1.0

—

16.15

—

(3050449) Albumin [Mass/time] in Urine collected for unspecified duration

0.00

0.21

0.0

1.9

—

74.34

—

(4268621) Lupus anticoagulant assay

0.00

0.21

0.0

2.0

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.6

—

0.17

—

(4195642) Thrombophilia screening test

0.00

0.20

0.0

1.4

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

138

1.20

0.19

1.2

1.3

0.93

5.53

u/ml

—

(1761868) Lipid panel - Serum or Plasma

275

1.16

0.19

2.0

2.8

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

104

1.18

0.13

4.2

21.13

21.66

—

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

1.17

0.10

6.4

3.9

4.75

4.50

pmol/l

—

(40768804) Tissue Pathology biopsy report

275

1.09

0.08

2.5

2.0

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.11

0.08

4.0

1.5

—

(21494755) Public health laboratory ask at order entry panel

1.10

0.07

1.4

—

(40758558) Short blood count panel - Blood

201

0.93

0.05

4.4

5.9

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

115

1.05

0.00

3.2

3.0

220.86

376.25

ng/l

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

105

1.06

0.00

2.2

1.7

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.0

1.4

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(3018333) Ribosomal P Ab [Presence] in Serum

0.00

0.0

1.2

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.0

1.4

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.2

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.0

1.7

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.0

1.4

—

(3024666) Lithium [Moles/volume] in Serum or Plasma

0.00

0.0

10.2

—

0.65

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

0.0

2.9

—

(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex

0.00

0.0

1.5

—

(4146454) Self-monitoring of blood glucose

0.00

0.0

2.5

—

(3035999) Lactate [Moles/volume] in Cerebral spinal fluid

0.00

0.0

1.3

—

1.54

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.0

1.4

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.2

—

(3023419) Bacteria identified in Sputum by Culture

0.00

0.0

3.1

—

(3008733) Herpes simplex virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.2

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

0.0

11.7

—

731.00

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

0.0

1.4

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

0.0

1.5

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.0

1.4

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.2

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.0

1.7

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(40759850) Jo-1 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(3019897) Erythrocyte [DistWidth] in Red Blood Cells by Automated count

0.00

0.0

2.8

—

13.28

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

0.0

13.0

—

1328.33

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

6.4

—

2.29

—

(3006442) Creatine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.1

—

69.86

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

-0.00

0.0

1.0

—

(44816808) CXCL13 Ag [Mass/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

130

1.00

-0.00

5.5

4.5

2.45

1.82

ug/l

0.43

118

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3009595) Pneumocystis jirovecii DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(4281824) Cell count and differential, peritoneal fluid

0.00

-0.00

0.0

1.0

—

(40760848) Basement membrane zone BP180 Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.1

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

-0.00

0.0

1.3

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.3

—

(3032700) Glomerular basement membrane Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3048469) 10-Hydroxycarbazepine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.0

—

50.86

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

-0.00

0.0

1.3

—

(3017817) Protein [Mass] in Urine collected for unspecified duration

0.00

-0.00

0.0

2.2

—

1364.00

—

(3020911) Cortisol [Moles/time] in 24 hour Urine

0.00

-0.00

0.0

1.6

—

50.40

—

(40768806) Pleura Pathology biopsy report

0.00

-0.00

0.0

1.6

—

(4010399) Spirometry for bronchospasm with prolonged evaluation after bronchodilator

0.94

-0.00

1.2

1.4

—

(37208534) Antinuclear antibody arbitrary concentration in serum

0.00

-0.00

0.0

1.0

—

(3016018) Differential panel - Cerebral spinal fluid

0.00

-0.00

0.0

1.1

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.3

—

(3045066) Thymidine kinase [Enzymatic activity/volume] in Serum

0.00

-0.00

0.0

1.2

—

18.36

—

(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

6.8

—

84.40

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

0.92

-0.00

1.4

2.0

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3033386) Bacteria [Presence] in Cerebral spinal fluid by Light microscopy

0.00

-0.00

0.0

1.3

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.1

—

(3042631) Mycobacterium sp identified in Specimen

0.00

-0.00

0.0

6.4

—

(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(21494890) Protein electrophoresis panel - 24 hour Urine

0.00

-0.00

0.0

1.6

—

Mortality – FinRegistry

↥

Association

Association between endpoint D3_CYSTSPLEEN and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have D3_CYSTSPLEEN.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: D3_CYSTSPLEEN – Cyst of spleen

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Cyst of spleen

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints