No definition available.
Congenital malformations of the respiratory system
EFO MESH Endpoint Browser PheWeb
Q17_CONGEN_MALFO_RESPI_SYSTEM
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
708 |
4. Check minimum number of eventsNone |
708 |
5. Include endpoints |
708 |
6. Filter based on genotype QC (FinnGen only) |
641 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 2
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- Q
- Name in latin
- Malformationes congenitae systematis respiratorii
Similar endpoints
↥List of similar endpoints to
Congenital malformations of the respiratory system
based on the number of shared cases.
Similar with more cases:
- Congenital malformations of the respiratory system, including avohilmo
- Congenital malformations, deformations and chromosomal abnormalities
- Congenital malformations, deformations and chromosomal abnormalities, including avohilmo
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7047 | 3406 | 3623 |
| Only index persons | 4802 | 2461 | 2341 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.10 | 0.10 | 0.10 |
| Only index persons | 0.09 | 0.09 | 0.09 |
| Median age at first event (years) | |||
| Whole population | 10.90 | 21.32 | 0.82 |
| Only index persons | 30.26 | 46.96 | 12.69 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 641 | 387 | 254 |
| Unadjusted period prevalence (%) | 0.13 | 0.14 | 0.12 |
| Median age at first event (years) | 51.10 | 53.66 | 47.20 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 666
- Matched controls
- 6655
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
UGC12
NOMESCO Finland
Flexible bronchoscopy
18.4
274.7
264
229
Q32.21
ICD-10 Finland
Secondary congenital bronchomalacia
2554.3
194.6
179
*
Q32.0
ICD-10 Finland
Congenital tracheomalacia
+∞
123.9
115
*
R03BB04
ATC
tiotropium bromide; inhalant
7.6
102.3
171
289
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
8.2
86.6
129
190
UGC02
NOMESCO Finland
Rigid bronchoscopy
35.2
72.1
46
14
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
13.4
67.6
66
54
J45.1
ICD-10 Finland
Nonallergic asthma
5.5
66.0
150
334
J45.9
ICD-10 Finland
Asthma, unspecified
4.2
65.5
249
833
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
5.5
62.2
139
304
R03DC03
ATC
montelukast; oral
4.2
62.1
226
729
J47
ICD-10 Finland
Bronchiectasis
14.3
62.0
58
44
R03AK06
ATC
salmeterol and fluticasone; inhalant
4.5
61.4
190
543
J46
ICD-10 Finland
Status asthmaticus
10.1
55.7
66
72
Q31.40
ICD-10 Finland
Congenital laryngomalasia
571.9
54.3
53
*
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
3.8
54.2
233
833
R03AC02
ATC
salbutamol; inhalant
3.9
52.4
510
3017
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.4
49.2
270
1118
Q32.20
ICD-10 Finland
Congenital bronchomalacia
+∞
48.5
46
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
5.1
48.5
115
262
J98.0
ICD-10 Finland
Diseases of bronchus, not elsewhere classified
73.2
47.9
54
8
R03BA08
ATC
ciclesonide; inhalant
4.8
44.8
115
279
XG410
NOMESCO Finland
Flow-volume spirometry
6.7
44.7
75
123
Q34.1
ICD-10 Finland
Congenital cyst of mediastinum
+∞
44.2
42
*
R03DA04
ATC
theophylline; systemic, rectal
6.8
43.8
73
119
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.1
43.2
410
2279
R06.0
ICD-10 Finland
Dyspnoea
3.1
42.1
263
1156
R03AK08
ATC
formoterol and beclometasone; inhalant
6.3
42.0
75
131
R03BA05
ATC
fluticasone; inhalant
3.2
41.6
226
915
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
7.3
40.5
62
92
R05
ICD-10 Finland
Cough
3.1
40.2
245
1057
R03BB01
ATC
ipratropium bromide; inhalant
7.0
39.4
63
98
H02AB06
ATC
prednisolone; systemic
2.9
39.0
386
2154
J45.8
ICD-10 Finland
Mixed asthma
7.1
36.6
57
86
R96
ICPC
Asthma
3.9
36.1
120
352
WX704
NOMESCO Finland
Intubation
4.4
35.6
100
259
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
3.0
33.5
198
828
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
5.3
32.6
69
141
TPH04
NOMESCO Finland
Cathetrisation of vein
2.8
31.1
205
905
J01MA14
ATC
moxifloxacin; systemic
3.9
30.5
98
279
J45.0
ICD-10 Finland
Predominantly allergic asthma
3.5
30.4
120
393
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
5.1
30.3
68
146
G47.3
ICD-10 Finland
Sleep apnoea
2.8
30.0
200
885
Z01.8
ICD-10 Finland
Other specified special examinations
2.7
29.8
213
977
R03BA02
ATC
budesonide; inhalant
2.9
29.3
181
768
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.9
29.0
170
702
Q33.2
ICD-10 Finland
Sequestration of lung
+∞
28.3
27
*
Q31.3
ICD-10 Finland
Laryngocele
+∞
28.3
27
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.7
27.6
68
158
WX725
NOMESCO Finland
Noninvasive ventilation
4.3
26.7
73
184
R03AC12
ATC
salmeterol; inhalant
5.0
26.7
60
129
Q30.8
ICD-10 Finland
Other congenital malformations of nose
+∞
26.2
25
*
GD1AD
NOMESCO Finland
Thorax CT examination
4.1
25.8
75
198
XG474
NOMESCO Finland
Exhalation nntrogen oxide
5.5
25.7
51
98
UDH02
NOMESCO Finland
Rhinopharyngoscopy
3.8
25.6
84
242
R03AK07
ATC
formoterol and budesonide; inhalant
2.6
24.6
184
852
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
5.4
24.6
50
98
R03AK11
ATC
formoterol and fluticasone; inhalant
7.0
24.4
38
57
R02
ICPC
Shortness of breath/dyspnoea
2.9
23.3
131
523
UDQ12
NOMESCO Finland
Flexible laryngoscopy
4.0
23.3
70
189
Q33.08
ICD-10 Finland
Congenital cystic lung
+∞
23.0
22
*
R03AC03
ATC
terbutaline; inhalant
2.9
22.8
127
504
R03BC03
ATC
nedocromil; inhalant
3.8
22.2
73
210
WX402
NOMESCO Finland
General anaesthesia
2.3
21.5
212
1105
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.6
21.4
154
696
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
21.3
227
1223
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
3.5
21.2
78
242
R03BA01
ATC
beclometasone; inhalant
2.9
20.8
114
448
J01FA06
ATC
roxithromycin; oral
2.2
19.8
274
1631
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
15.2
19.6
32
22
TPH07
NOMESCO Finland
Cathetrisation of artery
2.7
19.1
113
461
R04.2
ICD-10 Finland
Haemoptysis
5.5
18.4
36
68
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
3.3
18.4
75
248
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
20.0
18.3
27
14
H02AB04
ATC
methylprednisolone; systemic
2.6
18.0
118
506
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.8
17.8
100
396
Q32.10
ICD-10 Finland
Other congenital malformations of trachea
+∞
17.8
17
*
Q32.4
ICD-10 Finland
Other congenital malformations of bronchus
+∞
17.8
17
*
WX892
NOMESCO Finland
Monitored bed care
3.0
17.7
85
309
R06.2
ICD-10 Finland
Wheezing
3.5
17.7
63
191
R99
ICPC
Respiratory disease other
6.7
17.6
28
43
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.6
17.6
118
512
SPAT1059
SPAT
Spirometry at the office
3.9
17.5
54
148
J01MA12
ATC
levofloxacin; systemic
2.4
17.2
134
623
N03AX16
ATC
[U] pregabalin
2.2
16.9
170
883
C03CA01
ATC
furosemide; systemic
2.1
16.8
202
1126
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
5.1
16.6
35
71
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.0
16.6
409
2942
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
4.3
16.5
43
104
A02BC05
ATC
esomeprazole; systemic
2.0
16.4
277
1745
R06.1
ICD-10 Finland
Stridor
30.9
16.2
21
7
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.2
16.1
68
229
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
5.0
16.0
35
73
R03AK03
ATC
[U] fenoterol and ipratropium bromide
3.9
16.0
48
129
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
16.0
208
1191
Q31.1
ICD-10 Finland
Congenital subglottic stenosis
+∞
15.7
15
*
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
18.3
15.2
23
13
J01FA10
ATC
azithromycin; systemic
2.0
15.1
430
3203
J96.1
ICD-10 Finland
Chronic respiratory failure
5.7
14.9
28
51
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.5
14.8
52
156
R05
ICPC
Cough
2.0
14.7
221
1325
Q34.0
ICD-10 Finland
Anomaly of pleura
+∞
14.6
14
*
R06.5
ICD-10 Finland
Mouth breathing
2.7
14.6
86
348
TGC00
NOMESCO Finland
Bronchial lavation
4.7
14.6
34
75
Q30.9
ICD-10 Finland
Congenital malformation of nose, unspecified
153.1
14.5
15
*
SPAT1058
SPAT
PEF monitoring instruction
3.0
14.5
68
244
R03AC13
ATC
formoterol; inhalant
3.6
14.4
48
139
J45
ICD-10 Finland
Asthma
2.6
14.2
93
397
R01AD58
ATC
fluticasone, combinations; nasal
2.0
14.1
186
1062
R49.08
ICD-10 Finland
Other specified dysphonia
4.7
13.9
32
70
SPAT1263
SPAT
Sampling
1.9
13.8
291
1944
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
3.4
13.7
52
164
R03AL08
ATC
vilanterol, umeclidinium bromide and fluticasone furoate; inhalant
6.5
13.3
22
35
H02AB07
ATC
prednisone; oral
2.4
13.1
99
451
R01AD08
ATC
fluticasone; nasal
2.0
13.0
192
1137
J01MA02
ATC
ciprofloxacin; systemic
1.9
12.8
239
1529
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.8
12.7
275
1840
J42
ICD-10 Finland
Unspecified chronic bronchitis
12.6
12.7
22
18
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.0
12.6
183
1077
Q30.0
ICD-10 Finland
Choanal atresia
+∞
12.5
12
*
Q33.6
ICD-10 Finland
Hypoplasia and dysplasia of lung
+∞
12.5
12
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.2
12.4
113
558
XQ845
NOMESCO Finland
Dermatoscopy
5.5
12.4
24
45
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.8
12.2
65
249
R95
ICPC
Chron obstructive pulmonary disease
4.6
12.2
29
65
SPAT1301
SPAT
No procedures
1.9
12.1
221
1399
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.8
12.0
396
2989
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.9
11.6
34
90
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
4.1
11.6
32
81
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.9
11.6
56
204
Z93.0
ICD-10 Finland
Tracheostomy status
+∞
11.5
11
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.6
11.5
69
282
GBA32
NOMESCO Finland
Endoscopic dilatation of trachea
122.0
11.5
12
*
AA1AD
NOMESCO Finland
CT of head and brain
1.9
11.3
190
1166
R06.8
ICD-10 Finland
Other and unspecified abnormalities of breathing
4.9
11.3
25
53
A06AD11
ATC
lactulose; oral
2.2
11.2
99
481
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.2
11.0
101
498
N02AX02
ATC
tramadol; systemic, rectal
1.8
11.0
264
1803
R5140
NOMESCO Finland
Monitoring the use of the aid
2.3
11.0
87
404
WX720
NOMESCO Finland
Own respiration
3.2
11.0
45
149
N06AA09
ATC
amitriptyline; systemic
2.5
10.9
70
295
C07AB07
ATC
bisoprolol; oral
1.7
10.9
290
2039
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
15.8
10.9
17
11
J01AA02
ATC
doxycycline; systemic
1.8
10.8
468
3769
R51.80
ICD-10 Finland
Headache
2.0
10.8
136
757
F82
ICD-10 Finland
Specific developmental disorder of motor function
5.0
10.8
23
47
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
10.5
256
1750
R07.4
ICD-10 Finland
Chest pain, unspecified
1.8
10.5
187
1165
R01AD09
ATC
mometasone; nasal
1.7
10.5
304
2181
ZXD05
NOMESCO Finland
Urgent procedure
1.8
10.5
195
1232
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.0
10.5
126
689
Q32.11
ICD-10 Finland
Congenital tracheo-esophageal fissure
+∞
10.4
10
*
ZXA10
NOMESCO Finland
Bilateral
2.0
10.3
139
791
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
10.3
294
2100
UGB02
NOMESCO Finland
Tracheoscopy
23.8
10.3
14
6
J40
ICD-10 Finland
Bronchitis, not specified as acute or chronic
3.8
10.2
31
84
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.9
10.1
140
803
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.5
10.1
66
280
Z3229
NOMESCO Finland
Other healthcare associate professional
2.3
10.0
76
346
J38.6
ICD-10 Finland
Stenosis of larynx
40.7
10.0
12
*
DLD00
NOMESCO Finland
Reconstruction of cartilage of nose
26.4
9.8
13
5
XG413
NOMESCO Finland
Spirometry with oscillometry
7.5
9.8
22
30
WX722
NOMESCO Finland
PEEP
2.8
9.7
48
177
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.4
9.7
72
325
5191A
ICD-9 Finland
Other diseases of respiratory system, Other diseases of trachea and bronchus, not elsewhere classified
55.8
9.7
11
*
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.2
9.7
39
128
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.3
9.6
79
372
C01DA14
ATC
isosorbide mononitrate; oral
2.2
9.6
87
427
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
3.9
9.6
28
74
TDM10
NOMESCO Finland
Puncture of maxillary antrum
3.3
9.6
36
113
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.0
9.5
116
637
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.1
9.4
95
486
UKC02
NOMESCO Finland
Cystoscopy
2.1
9.4
94
479
N06AX11
ATC
mirtazapine; oral
1.7
9.4
219
1470
Q33.9
ICD-10 Finland
Congenital malformation of lung, unspecified
+∞
9.4
9
*
Q33.00
ICD-10 Finland
Solitary congenital cyst in the lungs
+∞
9.4
9
*
J01CA04
ATC
amoxicillin; systemic
2.0
9.4
569
4954
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
5.0
9.4
20
41
SPAT1262
SPAT
Handing over of treatment supplies
2.0
9.3
110
596
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
9.3
162
999
UDQ02
NOMESCO Finland
Direct laryngoscopy
7.4
9.3
21
29
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
2.8
9.2
48
182
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
4.4
9.2
23
54
A01AB09
ATC
miconazole; local oral
2.4
9.2
67
300
M50.3
ICD-10 Finland
Other cervical disc degeneration
4.5
9.1
22
50
N03AX12
ATC
[U] gabapentin; oral
2.0
9.1
107
580
UDC00
NOMESCO Finland
Ear microscopy
2.4
9.0
67
302
WX882
NOMESCO Finland
High dependency care
2.7
9.0
50
196
A02BC02
ATC
pantoprazole; systemic
1.7
9.0
407
3236
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.8
9.0
148
897
R4130
NOMESCO Finland
Speech therapy
2.9
8.9
41
145
DLD20
NOMESCO Finland
Rhinoplasty
24.4
8.9
12
5
SPAT1081
SPAT
Cardiorespiratory global assessment
3.1
8.9
38
129
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.9
8.9
128
743
R04
ICPC
Breathing problem other
3.0
8.8
39
135
A02BC01
ATC
omeprazole; systemic
1.8
8.8
166
1047
205
Kela drug reimbursment
Chronic hypertension
1.8
8.7
145
879
R03DC01
ATC
zafirlukast; oral
4.9
8.6
19
40
N06AX21
ATC
duloxetine; oral
2.1
8.6
86
438
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.7
8.6
196
1303
J41.0
ICD-10 Finland
Simple chronic bronchitis
10.2
8.6
16
16
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.9
8.5
108
601
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.8
8.4
167
1066
R29
ICPC
Respiratory symptom/complaint other
2.4
8.4
59
259
GCA18
NOMESCO Finland
Bronchoscopic dilatation of bronchus
91.1
8.4
9
*
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
6.8
8.4
20
30
J01FA09
ATC
clarithromycin; systemic
1.7
8.4
210
1431
Q32.18
ICD-10 Finland
Other congenital malformations of trachea
+∞
8.3
8
*
Q34.88
ICD-10 Finland
Other specified congenital malformations of respiratory system
+∞
8.3
8
*
GBB13
NOMESCO Finland
Revision of tracheostomy
+∞
8.3
8
*
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
3.2
8.3
32
102
ZXE20
NOMESCO Finland
More than three and less than five hours
2.0
8.3
99
538
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.8
8.3
142
869
XF600
NOMESCO Finland
Bloodpressure measurement
2.3
8.3
66
307
R13
ICD-10 Finland
Dysphagia
2.4
8.2
57
249
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.9
8.2
113
645
A02BA02
ATC
ranitidine; systemic
1.9
8.2
118
684
R01AD12
ATC
fluticasone furoate; nasal
1.7
8.2
208
1421
R1250
NOMESCO Finland
Evaluation of functional capability
3.5
8.1
28
83
R28
ICPC
Limited function/disability (R)
6.9
8.1
19
28
C08CA01
ATC
amlodipine; oral
1.7
8.1
219
1519
D38.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Mediastinum
17.4
8.1
12
7
B01AA03
ATC
warfarin; systemic
1.9
8.1
104
580
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
6.4
8.1
20
32
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
4.2
8.0
21
51
UJD02
NOMESCO Finland
Gastroscopy
2.8
8.0
39
143
UJF32
NOMESCO Finland
Coloscopy
1.7
8.0
157
999
WZC30
NOMESCO Finland
Teaching
1.9
8.0
115
666
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.2
7.9
65
306
J01DB01
ATC
cefalexin; oral
1.7
7.9
524
4519
A03FA02
ATC
cisapride; oral, rectal
2.4
7.8
53
229
GBB00
NOMESCO Finland
Tracheostomy
8.6
7.8
16
19
I50.9
ICD-10 Finland
Heart failure, unspecified
2.1
7.8
82
426
RF210, ,
NOMESCO Finland
3.5
7.7
26
76
DLD10
NOMESCO Finland
Reconstruction of cartilage and bone of nose
45.5
7.7
9
*
A01AB04
ATC
amphotericin B; local oral
2.8
7.6
38
141
A02BC03
ATC
lansoprazole; oral
1.7
7.6
168
1104
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
10.2
7.6
14
14
J34.2
ICD-10 Finland
Deviated nasal septum
2.7
7.5
40
154
R4110
NOMESCO Finland
Physiotherapy
1.6
7.5
198
1362
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
4.5
7.5
18
41
GBB96
NOMESCO Finland
Other tracheostomy procedure
80.9
7.4
8
*
M19.0
ICD-10 Finland
Primary arthrosis of other joints
2.1
7.4
68
335
XF400
NOMESCO Finland
ECG with 12 standard connections
1.8
7.4
114
674
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.8
7.4
37
138
M54.4
ICD-10 Finland
Lumbago with sciatica
1.8
7.3
115
683
R06AE07
ATC
cetirizine; oral
1.6
7.3
279
2092
1240
FHL
Bronchoscopy
9.5
7.3
14
15
Z43.0
ICD-10 Finland
Attention to tracheostomy
+∞
7.3
7
*
Q33.80
ICD-10 Finland
Congenital [cystic] adenomatoid malformation of lung
+∞
7.3
7
*
Q33.4
ICD-10 Finland
Congenital bronchiectasis
+∞
7.3
7
*
J98.8
ICD-10 Finland
Other specified respiratory disorders
+∞
7.3
7
*
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
3.9
7.3
21
55
XA800
NOMESCO Finland
Neuropsychological investigation
2.4
7.3
51
224
ZXA00
NOMESCO Finland
Right side
1.7
7.3
164
1080
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
3.2
7.2
28
90
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.0
7.2
75
388
C07AB02
ATC
metoprolol; systemic
1.8
7.2
114
680
J21.90
ICD-10 Finland
Acute obstructive bronchitis in children
2.9
7.2
34
123
GDC00
NOMESCO Finland
Lobectomy of lung
20.3
7.1
10
5
R44
ICPC
Respiratory, Preventive immunization/medic
6.1
7.1
18
30
XG405
NOMESCO Finland
Education on PEF monitoring
5.7
7.1
19
34
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
3.2
7.1
28
91
FM2CE, ,
NOMESCO Finland
3.2
7.0
27
86
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.4
7.0
47
202
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.5
7.0
24
71
A03CA02
ATC
clidinium and psycholeptics; oral
2.7
7.0
37
142
C03DA01
ATC
spironolactone; oral
2.0
7.0
79
421
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
2.1
7.0
70
357
61
HP
Catheterization and pressure measurement of the left side of the heart
5.9
6.9
18
31
DQB10
NOMESCO Finland
Endoscopic excision of lesion of larynx
7.6
6.9
15
20
J20
ICD-10 Finland
Acute bronchitis
2.0
6.9
75
394
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.6
6.9
38
149
H65.3
ICD-10 Finland
Chronic mucoid otitis media
2.5
6.8
42
174
7862A
ICD-9 Finland
Symptoms involving respiratory system and other chest symptoms, Cough
11.1
6.8
12
11
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
3.7
6.8
21
58
UGC18
NOMESCO Finland
Flexible bronchoscopy with biopsy of lung
16.9
6.8
10
6
RK290, ,
NOMESCO Finland
16.9
6.8
10
6
R10.0
ICD-10 Finland
Acute abdomen
3.4
6.7
24
73
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.1
6.7
66
334
R07.3
ICD-10 Finland
Other chest pain
2.0
6.7
73
384
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
2.8
6.7
33
122
WX734
NOMESCO Finland
JET-ventilation
22.8
6.7
9
*
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.6
6.6
37
146
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.5
6.6
254
1896
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.8
6.6
111
672
-1, ,
ICPC
2.7
6.6
34
129
R50.9
ICD-10 Finland
Fever, unspecified
1.7
6.6
125
785
J20.5
ICD-10 Finland
Acute bronchitis due to respiratory syncytial virus
6.9
6.5
15
22
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
3.7
6.5
20
55
I50.0
ICD-10 Finland
Congestive heart failure
2.4
6.5
45
197
R62.0
ICD-10 Finland
Delayed milestone
3.0
6.5
28
96
R05FA02
ATC
opium derivatives and expectorants; systemic
1.6
6.5
223
1623
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
6.5
138
893
P85
ICPC
Mental retardation
5.8
6.5
17
30
SPAT1360
SPAT
Extensive global examination
2.4
6.5
44
191
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.3
6.5
24
75
A28
ICPC
Limited function/disability NOS
1.8
6.4
113
693
DQW99
NOMESCO Finland
Other operation on larynx
70.5
6.4
7
*
6BB16, ,
NOMESCO Finland
70.5
6.4
7
*
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
6.6
6.4
15
23
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.0
6.3
70
370
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.9
6.3
84
473
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.0
6.3
66
342
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.9
6.3
80
444
Q30.3
ICD-10 Finland
Congenital perforated nasal septum
+∞
6.3
6
*
Q31.48
ICD-10 Finland
Other congenital laryngeal warts
+∞
6.3
6
*
DQD40
NOMESCO Finland
Plastic repair of larynx
+∞
6.3
6
*
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
6.2
156
1052
XG466
NOMESCO Finland
Sleep oxymetry
3.2
6.2
24
77
H02AB09
ATC
hydrocortisone; systemic
2.6
6.2
34
133
ZXC10
NOMESCO Finland
Use of laser
3.4
6.2
22
67
SPAT1305
SPAT
Counselling and guidance related to physical exercise
2.1
6.1
61
310
R09.3
ICD-10 Finland
Abnormal sputum
7.8
6.1
13
17
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.6
6.1
35
140
WX702
NOMESCO Finland
Supraglottic ventilation device
2.3
6.1
43
190
GX1E5
NOMESCO Finland
Flow volume spirometry and bronchodilation test
8.7
6.1
12
14
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
6.1
250
1888
L28
ICPC
Limited function/disability (L)
1.7
6.0
116
729
SAA04
NOMESCO Finland
Special examination of mouth
2.2
6.0
52
250
J01DA01
ATC
[U] cefalexin
1.5
6.0
353
2863
RF120, ,
NOMESCO Finland
6.1
6.0
15
25
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
112
176
7.44
70.41
3.6
2.6
—
—
—
0
0
185
512
4.61
62.38
2.0
1.4
106.14
229.47
u/ml
1.37
173
471
82
119
7.71
54.98
1.4
1.4
—
—
—
0
0
139
396
4.17
43.98
4.6
4.1
133.80
217.10
ng/l
2.31
128
366
50
65
8.23
36.56
1.6
1.4
1.50
7.50
u/ml
1.44
38
41
84
224
4.14
28.55
2.0
1.8
—
—
—
0
0
177
765
2.79
27.52
3.1
2.0
—
—
—
0
0
173
739
2.81
27.51
3.2
2.0
—
—
—
0
0
209
992
2.61
26.90
3.4
2.1
—
—
—
0
0
59
131
4.84
25.23
1.8
1.6
—
—
—
0
0
50
98
5.43
24.64
1.9
1.7
—
—
—
0
0
80
230
3.81
24.39
2.4
1.9
—
—
—
0
0
140
569
2.85
24.18
3.8
3.6
9.49
9.62
g/l
0.15
134
530
70
188
4.04
23.46
1.7
1.5
—
—
—
0
0
374
2463
2.18
21.22
19.4
12.8
1.25
1.22
inr
0.54
329
2032
488
3593
2.34
20.73
12.5
11.3
4.27
3.92
e9/l
2.29
440
3049
146
659
2.55
20.22
15.0
9.6
1.58
0.75
mmol/l
2.50
133
557
36
64
5.88
19.63
4.1
3.5
—
—
—
0
0
424
2990
2.15
19.45
8.2
7.6
15.35
14.57
umol/l
0.20
409
2844
311
1989
2.06
18.12
4.7
3.9
27.64
32.89
u/l
3.16
304
1898
228
1305
2.13
17.84
3.0
2.5
1.29
1.29
mg/l
0.00
173
1029
201
1099
2.19
17.66
6.5
4.1
168.88
442.56
ng/l
1.82
153
835
367
2509
2.03
17.58
7.6
6.0
35.47
36.11
g/l
1.20
345
2376
34
66
5.37
16.89
1.1
1.1
—
—
—
0
0
164
845
2.25
16.55
8.6
8.8
1.97
1.46
mmol/l
1.18
146
714
258
1585
2.02
16.40
5.3
3.8
1052.26
1327.16
ng/l
0.41
232
1343
422
3076
2.01
16.36
18.0
9.8
1.22
1.22
mmol/l
0.25
380
2725
459
3467
2.04
15.84
11.8
6.7
6.61
6.52
mmol/l
0.42
444
3290
273
1749
1.95
15.08
3.4
2.8
136.31
63.69
u/l
0.42
259
1626
50
146
3.62
14.81
1.4
1.4
—
—
—
0
0
94
410
2.50
13.69
2.1
1.7
—
—
—
0
0
29
61
4.92
13.17
1.2
1.5
—
—
—
0
0
382
2821
1.83
12.81
17.1
9.8
1.21
1.22
mmol/l
2.18
358
2635
134
701
2.14
12.72
2.9
2.5
325.77
362.89
nmol/l
1.55
123
666
35
89
4.09
12.58
3.0
4.4
—
—
—
0
0
99
459
2.36
12.58
1.6
1.5
—
—
—
0
0
174
1009
1.98
12.46
3.2
2.7
12.77
13.11
umol/l
0.25
160
947
41
121
3.54
11.96
1.4
1.8
—
—
—
0
0
356
2610
1.78
11.88
4.0
3.0
—
—
estimate
—
0
0
402
3101
1.75
10.80
5.8
4.1
0.00
0.53
estimate
0.51
80
582
511
4231
1.89
10.77
7.1
4.6
12.39
11.12
mm/h
1.26
496
3964
247
1677
1.75
10.38
2.6
2.2
163.09
214.50
u/l
0.98
235
1605
14
6
23.77
10.27
4.1
1.5
42.07
42.17
umol/l
—
14
6
397
3080
1.71
10.17
5.8
4.1
18.17
2.64
estimate
0.40
83
615
124
683
2.00
10.09
14.4
10.1
1.76
1.28
mmol/l
1.04
95
514
165
1002
1.86
10.03
8.5
6.5
0.83
0.81
mmol/l
0.94
154
961
53
203
2.75
9.99
3.1
2.1
1.17
2.56
ug/l
0.48
47
187
26
63
4.25
9.96
2.6
2.9
1.20
1.20
mmol/l
0.31
26
63
26
64
4.18
9.77
2.6
2.8
105.65
105.06
mmol/l
0.24
26
64
157
947
1.86
9.72
3.3
2.7
2.39
2.38
g/l
0.04
143
883
26
65
4.12
9.57
2.6
2.8
3.95
4.05
mmol/l
0.56
26
65
32
94
3.52
9.42
3.1
3.8
327.54
186.46
e6/l
1.30
24
61
26
66
4.06
9.39
1.9
1.3
—
—
—
0
0
43
152
2.95
9.39
1.9
2.0
—
—
—
0
0
88
440
2.15
9.25
2.9
3.2
66.20
66.61
g/l
0.20
79
413
31
91
3.52
9.14
2.7
3.9
646.13
506.09
e6/l
0.69
23
56
302
2223
1.65
9.08
5.6
3.8
0.04
0.02
estimate
0.36
68
502
206
1372
1.72
9.04
5.0
4.0
1.02
1.02
kg/l
0.21
152
939
30
88
3.52
8.86
1.7
1.9
—
—
—
0
0
504
4250
1.76
8.84
11.1
8.1
85.74
89.79
u/l
0.90
487
4040
127
736
1.89
8.84
14.8
9.8
5.25
5.05
kpa
2.44
122
720
386
3042
1.64
8.70
5.8
4.1
0.00
0.00
estimate
-0.00
86
607
144
881
1.81
8.40
3.4
2.8
21.03
22.20
%
0.46
131
831
44
169
2.71
8.26
1.3
1.5
—
—
—
0
0
72
354
2.16
7.88
6.1
8.8
0.59
0.61
%
0.20
72
354
234
1663
1.63
7.80
4.6
4.2
7.43
18.91
mg/mmol
0.53
144
1054
223
1567
1.63
7.77
2.9
2.6
2.77
2.83
mg/l
0.09
199
1368
154
990
1.72
7.50
13.1
8.6
1.16
1.18
mmol/l
0.15
144
931
53
234
2.37
7.49
1.2
1.2
—
—
—
0
0
97
546
1.91
7.32
6.9
5.5
71.45
73.02
ng/l
0.09
88
499
266
1975
1.58
7.26
5.1
3.8
28.48
65.94
ng/l
0.66
180
1358
160
1060
1.67
6.91
1.9
1.7
48092162.42
26204260.19
pmol/l
0.18
131
893
342
2707
1.54
6.91
3.7
2.9
78.51
76.35
nmol/l
0.81
319
2476
358
2868
1.53
6.80
3.9
3.3
110.19
110.68
ug/l
0.01
341
2694
258
1926
1.55
6.76
4.0
3.9
6.80
7.57
mmol/l
2.03
228
1661
63
313
2.12
6.72
2.1
1.4
—
—
—
0
0
39
157
2.57
6.71
10.7
9.1
178.60
319.50
iu/ml
—
10
20
468
3986
1.58
6.67
4.1
3.4
—
—
—
0
0
36
141
2.64
6.54
1.8
1.8
—
—
—
0
0
30
107
2.89
6.49
1.8
1.8
—
—
—
0
0
106
642
1.77
6.30
15.6
10.8
8.26
7.55
mmol/l
0.53
97
621
14
20
7.12
6.24
4.0
6.8
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
40
170
2.44
6.17
14.7
7.2
0.36
0.35
iu/ml
0.03
23
96
220
1625
1.53
5.88
5.5
3.4
0.00
0.05
estimate
0.52
69
484
262
2009
1.50
5.85
5.6
3.9
16.45
82.95
e6/l
1.26
206
1509
152
1044
1.59
5.57
1.3
1.3
38.35
31.31
iu/ml
0.14
42
319
33
137
2.48
5.37
1.0
1.1
—
1.27
—
0
16
435
3727
1.48
5.34
4.7
3.8
43.24
44.96
u/l
0.25
420
3537
73
416
1.85
5.29
2.5
2.5
12.55
14.75
au/ml
—
10
35
123
817
1.62
5.15
1.8
1.7
943.36
1197.99
nmol/l
3.76
96
614
230
1758
1.47
5.06
5.1
3.7
0.18
0.37
e6/l
2.65
177
1255
187
1371
1.50
5.06
3.8
3.5
338.77
331.89
umol/l
0.35
165
1220
552
5004
1.60
4.92
35.6
20.4
13.70
13.53
%
2.29
547
4960
113
745
1.62
4.87
4.7
4.4
5.72
7.22
umol/l
0.74
101
653
34
150
2.33
4.87
1.9
1.3
—
—
—
0
0
34
150
2.33
4.87
1.9
1.3
—
—
—
0
0
138
972
1.53
4.46
1.3
1.3
22.54
11.81
u/ml
0.55
52
370
22
82
2.74
4.45
1.1
1.5
—
—
—
0
0
15
45
3.38
4.34
1.3
1.2
143.13
99.07
pmol/l
1.77
15
45
204
1562
1.44
4.33
1.8
1.6
21.12
21.10
nmol/l
0.00
181
1318
65
381
1.78
4.32
1.3
1.3
67.72
30.63
au/ml
—
5
22
192
1456
1.45
4.28
1.8
1.8
—
—
—
0
0
205
1581
1.43
4.16
1.8
1.6
2.07
2.13
g/l
0.19
144
910
154
1129
1.47
4.07
4.1
3.4
0.82
0.82
e6/l
0.00
89
565
147
1068
1.48
4.07
4.7
3.6
4.10
2.22
e6/l
0.87
85
510
285
2333
1.39
4.07
2.4
2.1
101.65
97.39
pmol/l
0.73
150
1212
48
262
1.90
4.01
1.6
1.9
3.78
6.10
iu/ml
0.73
13
59
68
414
1.71
3.97
4.2
4.1
1.24
1.23
mmol/l
0.38
57
358
63
376
1.74
3.95
3.0
1.7
—
—
—
0
0
608
5711
1.73
3.95
33.2
15.8
22.43
22.94
mg/l
0.17
565
4582
176
1332
1.44
3.93
4.5
3.1
4.45
5.87
e6/l
0.97
158
1217
188
1447
1.42
3.81
3.9
2.7
—
—
—
0
0
67
413
1.69
3.75
2.5
2.4
4.53
6.76
ug/l
1.42
56
366
32
155
2.12
3.72
2.2
1.7
18.40
22.38
ng/l
0.67
32
155
497
4491
1.42
3.71
5.8
4.3
14.74
14.74
pmol/l
0.02
476
4137
15
51
2.98
3.59
1.7
1.4
36205.17
51236.62
e6/l
—
6
26
126
910
1.47
3.57
2.3
2.7
168.80
100.37
ug/g
0.80
104
745
14
46
3.09
3.54
1.0
1.2
—
—
—
0
0
12
31
3.92
3.50
2.2
1.6
—
—
—
0
0
12
31
3.92
3.50
2.2
1.6
—
—
—
0
0
12
31
3.92
3.50
2.2
1.6
—
—
—
0
0
12
31
3.92
3.50
2.2
1.6
—
—
—
0
0
45
253
1.83
3.46
1.2
1.2
2.62
2.50
u/ml
0.03
28
169
37
196
1.94
3.40
1.5
1.4
297.18
309.42
ug/g
0.15
22
114
560
5204
1.47
3.32
7.0
5.3
1.96
1.93
mu/l
0.24
540
4860
204
1628
1.36
3.26
5.6
4.1
0.00
0.01
estimate
0.74
74
575
31
158
2.01
3.19
1.2
1.2
—
—
—
0
0
15
56
2.72
3.07
1.8
1.4
3003.80
1687.50
e6/l
—
10
36
23
106
2.21
3.05
2.3
1.9
6.08
4.89
mmol/24h
0.74
18
93
544
5049
1.42
3.05
5.8
4.8
5.82
5.87
mmol/l
0.44
514
4646
14
51
2.78
2.99
1.1
1.7
—
—
—
0
0
29
148
2.00
2.98
2.0
1.4
—
—
—
0
0
15
57
2.67
2.97
1.9
1.6
—
—
—
0
0
15
57
2.67
2.97
1.9
1.6
—
—
—
0
0
15
57
2.67
2.97
1.9
1.6
—
—
—
0
0
34
186
1.87
2.88
1.6
3.3
48.58
10.29
e6/l
0.55
26
132
34
187
1.86
2.83
1.7
3.4
1970.96
1644.76
e6/l
0.07
27
136
27
138
2.00
2.78
2.7
4.1
1.16
2.56
ratio
1.55
16
77
614
5867
1.59
2.64
17.1
12.2
24.98
25.90
u/l
1.04
601
5707
28
148
1.93
2.64
1.3
1.2
—
8.60
—
0
10
10
30
3.37
2.61
1.2
1.0
—
—
—
0
0
21
100
2.13
2.61
3.9
3.2
13.24
18.25
mu/l
0.49
21
95
28
149
1.92
2.59
2.9
4.4
33.96
87.10
mg/l
0.72
22
128
28
149
1.92
2.59
2.8
4.4
35.05
64.51
mg/l
0.60
22
127
32
180
1.82
2.51
1.2
1.2
13.49
11.15
u/ml
—
7
31
31
173
1.83
2.50
1.5
1.3
—
—
—
0
0
34
196
1.77
2.47
1.6
1.5
0.02
0.11
iu/ml
—
5
31
8
21
3.84
2.46
2.6
1.9
—
—
—
0
0
8
21
3.84
2.46
2.6
1.9
—
—
—
0
0
236
1989
1.29
2.46
3.4
3.3
2.34
2.37
mmol/l
2.36
213
1810
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
14
57
2.49
2.46
1.2
1.2
—
—
—
0
0
11
38
2.92
2.42
1.3
1.6
—
—
—
0
0
9
27
3.36
2.39
11.0
6.9
4.96
4.89
kpa
—
9
27
80
573
1.45
2.38
2.9
2.6
31.23
35.10
u/l
0.50
71
469
8
22
3.66
2.37
2.6
1.8
—
—
—
0
0
18
84
2.17
2.36
1.4
1.3
—
—
—
0
0
33
192
1.75
2.34
2.1
2.0
276.26
188.30
u/ml
0.37
17
95
11
40
2.78
2.28
6.7
2.5
—
—
—
0
0
23
120
1.95
2.27
7.4
4.5
9.39
7.96
pmol/l
0.29
23
120
15
66
2.30
2.25
3.4
4.4
26.00
89.52
u/ml
—
5
17
52
345
1.55
2.24
1.6
1.8
37.33
23.33
iu/l
1.73
44
264
5
9
5.58
2.21
18.6
15.9
9.50
9.62
%
—
5
9
28
158
1.80
2.20
1.2
1.1
0.93
11.14
u/ml
4.59
17
90
62
430
1.49
2.18
2.9
3.1
67.24
68.01
ml/min/173m2
0.05
25
183
74
532
1.44
2.17
5.2
3.3
—
—
—
0
0
7
19
3.71
2.15
5.1
10.4
—
—
—
0
0
544
5134
1.32
2.06
5.6
4.9
1.43
1.48
mmol/l
2.06
512
4791
7
20
3.52
2.06
1.0
1.0
174.43
156.10
g/l
—
7
20
521
4890
1.30
2.05
4.7
4.2
1.28
1.27
mmol/l
0.23
492
4542
29
170
1.74
2.03
1.2
1.1
3.89
7.22
u/ml
0.58
19
106
21
111
1.92
2.02
1.7
1.7
—
—
—
0
0
10
38
2.65
2.01
2.1
1.6
57.20
29.80
u/ml
—
5
5
7
21
3.35
1.97
1.1
1.2
—
—
—
0
0
6
16
3.77
1.93
1.0
1.3
—
—
—
0
0
32
197
1.65
1.89
3.8
1.9
—
—
—
0
0
546
5172
1.30
1.89
5.7
5.0
4.52
4.64
mmol/l
1.91
521
4848
5
12
4.19
1.82
2.0
3.2
—
—
—
0
0
263
2309
1.23
1.82
2.3
2.0
1.35
1.35
mmol/l
0.04
232
1983
29
177
1.67
1.78
3.0
2.0
85.50
123.18
au/ml
0.92
12
73
13
60
2.19
1.78
1.2
1.2
—
—
—
0
0
6
18
3.35
1.75
1.7
2.2
401.83
6.49
ug/l
—
6
18
8
30
2.68
1.72
1.4
1.7
—
—
—
0
0
61
444
1.41
1.71
1.3
1.2
—
0.88
—
0
5
60
436
1.41
1.70
1.3
1.3
106.27
156.57
u/ml
0.88
26
168
25
149
1.70
1.68
1.1
1.1
0.05
0.59
u/ml
0.81
13
69
6
19
3.17
1.66
18.3
4.1
4.96
4.67
kpa
—
6
19
6
19
3.17
1.66
18.3
4.1
10.65
10.64
kpa
—
6
19
22
128
1.74
1.62
1.5
1.4
—
—
—
0
0
8
32
2.52
1.60
1.4
1.7
—
—
—
0
0
8
32
2.52
1.60
2.1
1.7
99.75
108.15
ng/l
—
8
32
34
224
1.54
1.57
1.2
1.2
0.75
0.87
u/ml
0.09
16
146
29
184
1.60
1.56
3.1
2.0
—
—
—
0
0
547
5217
1.27
1.55
6.4
5.6
2.62
2.72
mmol/l
1.87
513
4872
639
6239
1.58
1.54
43.1
24.1
263.13
256.96
e9/l
1.53
630
6070
29
186
1.58
1.50
3.4
1.7
—
—
—
0
0
639
6242
1.57
1.49
43.0
24.1
4.50
4.50
e12/l
0.15
630
6053
34
227
1.52
1.49
1.2
1.2
1.66
1.97
u/ml
0.11
21
157
34
228
1.52
1.46
1.2
1.2
5.67
6.00
u/ml
0.03
20
161
11
52
2.13
1.45
1.4
1.3
—
—
—
0
0
6
22
2.74
1.43
1.2
1.1
—
—
—
0
0
27
173
1.58
1.42
5.1
4.4
1.79
1.37
mmol/l
0.55
27
166
7
29
2.43
1.39
1.6
1.1
—
—
—
0
0
47
635
0.72
1.38
5.2
4.7
35.58
32.06
%
1.16
31
425
516
4910
1.22
1.37
7.9
6.2
39.38
38.84
mmol/mol
0.71
484
4628
34
233
1.48
1.34
1.6
2.1
10.67
8.26
u/l
0.36
26
157
35
244
1.46
1.28
1.7
1.7
—
—
—
0
0
14
77
1.83
1.26
1.9
2.9
31.64
32.21
pg
0.22
14
77
6
25
2.41
1.24
4.2
6.5
—
—
—
0
0
11
57
1.94
1.17
1.4
1.1
—
—
—
0
0
0
35
0.00
1.15
0.0
1.3
—
9.01
—
0
30
5
20
2.51
1.15
1.0
1.1
—
—
—
0
0
28
193
1.47
1.10
1.3
1.3
—
—
—
0
0
18
112
1.62
1.09
1.6
1.2
—
—
—
0
0
11
59
1.88
1.07
1.4
1.1
—
—
—
0
0
11
59
1.88
1.07
1.4
1.1
—
—
—
0
0
13
75
1.75
1.03
1.1
1.1
—
—
—
0
0
11
60
1.85
1.03
1.4
1.2
—
79.00
—
0
6
193
1725
1.17
1.02
1.5
1.5
2.95
1.96
u/ml
0.21
47
418
7
35
2.01
1.00
1.1
1.0
—
—
—
0
0
5
23
2.18
0.98
2.2
1.8
—
—
—
0
0
9
50
1.81
0.97
2.3
1.2
—
—
—
0
0
9
50
1.81
0.97
2.8
1.5
—
—
—
0
0
12
197
0.60
0.95
1.0
1.2
0.82
0.90
g/l
0.81
12
197
11
62
1.79
0.94
1.4
1.1
—
—
—
0
0
66
537
1.25
0.94
3.0
4.4
11.25
28.71
ug/l
0.55
53
439
45
573
0.77
0.93
2.4
2.0
3.71
3.46
ratio
0.57
33
452
21
142
1.49
0.93
3.0
2.2
0.00
0.00
g/l
-0.00
21
135
25
176
1.44
0.91
3.3
3.8
1.80
3.43
index
0.86
15
109
12
71
1.70
0.89
1.3
1.2
—
—
—
0
0
8
43
1.87
0.87
1.4
2.0
128.39
139.68
ng/l
—
8
37
8
44
1.83
0.86
2.9
1.7
—
—
—
0
0
12
191
0.62
0.85
1.0
1.1
1.44
1.55
g/l
0.34
12
191
10
57
1.76
0.84
1.4
1.1
—
—
—
0
0
6
32
1.88
0.82
7.7
5.6
—
—
—
0
0
6
32
1.88
0.82
1.3
1.4
186.33
72.41
umol/l
—
6
32
12
73
1.65
0.82
1.1
1.1
—
—
—
0
0
22
155
1.43
0.81
2.7
2.0
2.57
4.22
iu/l
0.95
11
61
0
26
0.00
0.78
0.0
1.3
—
0.64
—
0
26
12
74
1.63
0.78
1.3
1.4
—
—
—
0
0
5
24
2.09
0.74
1.6
1.6
2.00
1.35
u/field
—
5
18
5
24
2.09
0.74
1.0
3.0
250.00
211.08
u/l
—
5
24
5
24
2.09
0.74
1.0
1.2
—
—
—
0
0
30
228
1.33
0.74
1.9
2.4
21919.59
4963.07
u/l
—
8
79
7
38
1.85
0.73
1.9
3.0
1709.43
750.16
mg
—
7
38
11
68
1.63
0.72
1.1
1.5
343.64
287.61
mu/l
0.25
11
51
60
711
0.83
0.69
2.9
3.0
0.64
0.73
ug/l
0.43
39
434
19
135
1.42
0.69
1.3
1.2
—
—
—
0
0
5
27
1.86
0.68
9.4
11.5
—
371.33
—
0
6
16
111
1.45
0.66
2.3
2.4
73.31
76.39
ug/min
—
8
60
38
306
1.26
0.63
3.8
2.8
33.53
87.55
u/ml
0.73
38
295
21
155
1.37
0.63
2.5
4.0
17.85
21.82
nmol/l
0.74
21
147
6
101
0.59
0.62
1.2
1.7
—
—
—
0
0
28
217
1.30
0.62
2.3
3.2
4108.24
1063.01
u/ml
0.33
21
186
11
71
1.56
0.62
1.2
1.0
—
—
—
0
0
5
30
1.67
0.61
1.0
1.2
—
—
—
0
0
5
30
1.67
0.61
1.0
2.0
0.96
7.71
nmol/l
—
5
25
8
50
1.61
0.61
1.1
1.2
—
—
—
0
0
8
51
1.57
0.60
1.1
1.2
—
—
—
0
0
0
21
0.00
0.60
0.0
1.5
—
—
—
0
0
0
22
0.00
0.59
0.0
1.0
—
21.96
—
0
9
23
175
1.32
0.58
2.8
1.8
39.13
37.40
nmol/l
0.16
23
167
0
23
0.00
0.58
0.0
1.0
—
39.80
—
0
23
0
23
0.00
0.58
0.0
1.3
—
—
—
0
0
0
23
0.00
0.58
0.0
1.0
—
2.86
—
0
11
34
417
0.80
0.57
1.0
1.1
—
—
—
0
0
132
1203
1.12
0.54
5.3
5.1
4.48
2.13
ug/l
0.37
123
1079
36
434
0.82
0.52
2.3
1.8
3.44
3.45
mmol/l
0.02
24
313
6
40
1.50
0.51
4.0
4.2
1.17
1.00
%
—
6
40
507
4943
1.10
0.50
23.6
14.6
83.24
83.74
ml/min/173m2
0.19
455
4474
24
189
1.28
0.50
1.2
2.1
—
—
—
0
0
94
846
1.13
0.48
1.7
1.5
—
—
—
0
0
27
218
1.25
0.47
1.3
1.4
155.89
259.80
miu/ml
—
9
102
7
51
1.38
0.44
1.1
1.5
—
—
—
0
0
13
95
1.37
0.44
1.1
1.1
—
—
—
0
0
5
32
1.57
0.42
1.8
1.1
233.20
188.40
iu/ml
—
5
32
8
57
1.41
0.42
3.9
5.1
0.63
0.65
index
—
8
57
41
352
1.17
0.41
2.5
2.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
12.12
—
0
7
5
34
1.47
0.40
1.0
1.1
—
—
—
0
0
5
34
1.47
0.40
1.2
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
2.69
—
0
6
23
278
0.82
0.37
1.7
1.6
0.07
0.31
mg/l
—
9
122
5
37
1.35
0.37
1.6
1.3
46.80
104.81
nmol/l
—
5
25
47
413
1.15
0.36
2.9
2.2
—
—
—
0
0
5
77
0.65
0.36
1.2
1.6
68.16
53.19
ug/l
—
5
77
22
181
1.22
0.34
1.3
1.4
—
—
—
0
0
6
47
1.28
0.32
1.2
1.0
—
—
—
0
0
7
53
1.32
0.31
1.3
1.3
47.43
68.60
u/l
—
7
48
7
53
1.32
0.31
1.1
1.1
179.29
222.77
mg/l
—
7
48
7
57
1.23
0.29
1.3
1.5
8.47
3.73
ug/l
—
7
49
100
939
1.08
0.25
5.6
4.4
19.88
22.02
%
0.74
50
411
61
562
1.09
0.24
8.0
6.4
—
—
—
0
0
5
38
1.32
0.23
2.2
1.2
—
—
—
0
0
5
38
1.32
0.23
2.2
1.2
—
—
—
0
0
5
39
1.28
0.23
1.0
1.1
17.72
41.87
iu/ml
—
5
39
69
738
0.93
0.21
3.0
2.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
15
177
0.84
0.21
1.8
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
0.02
—
0
7
6
50
1.20
0.19
1.5
1.0
—
—
—
0
0
111
1062
1.05
0.17
2.8
2.7
2.45
2.45
mmol/l
0.18
94
953
5
68
0.73
0.17
2.2
1.4
—
—
—
0
0
5
69
0.72
0.17
2.4
1.4
—
—
—
0
0
20
177
1.13
0.16
1.3
1.2
—
—
—
0
0
16
140
1.15
0.15
1.3
1.0
20.86
19.35
mmol/l
1.23
16
134
8
99
0.81
0.13
1.9
4.2
9.54
2764.80
u/ml
—
8
94
8
100
0.80
0.13
1.6
1.4
0.20
0.29
nmol/l
—
8
74
22
200
1.10
0.12
2.4
1.4
—
—
—
0
0
10
85
1.18
0.12
1.0
1.2
—
13.35
—
0
26
34
321
1.06
0.09
1.2
1.3
—
—
—
0
0
11
97
1.14
0.09
1.2
1.1
5.60
3.23
u/ml
—
5
48
19
175
1.09
0.08
1.3
1.2
—
—
—
0
0
5
64
0.78
0.08
2.4
1.4
—
—
—
0
0
5
64
0.78
0.08
2.4
1.4
—
—
—
0
0
5
65
0.77
0.08
2.4
1.4
—
—
—
0
0
7
68
1.03
0.08
1.3
1.3
5.40
7.45
mmol/l
—
7
55
8
75
1.07
0.07
1.0
1.0
—
—
—
0
0
9
105
0.85
0.06
2.3
1.5
—
—
—
0
0
10
110
0.91
0.05
2.2
1.5
1.32
0.93
ratio
—
5
67
10
110
0.91
0.05
2.2
1.5
1.25
1.29
ratio
—
5
67
10
110
0.91
0.05
2.2
1.5
1.70
1.09
ratio
—
5
67
22
210
1.05
0.03
1.5
1.6
4.87
12.79
u/ml
—
6
40
68
690
0.98
0.02
2.8
2.2
—
—
—
0
0
16
154
1.04
0.00
1.5
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
13.40
—
0
5
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
4.1
—
55.40
—
0
7
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
55.67
—
0
6
0
6
0.00
-0.00
0.0
2.3
—
15.40
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.0
—
5.70
—
0
6
7
72
0.97
-0.00
1.6
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint Q17_CONGEN_MALFO_RESPI_SYSTEM and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_CONGEN_MALFO_RESPI_SYSTEM | 1.645 [1.4, 1.93] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.609 |
During the follow-up period (1.1.1998 — 31.12.2019), 351 out of 2898 females with Q17_CONGEN_MALFO_RESPI_SYSTEM died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_CONGEN_MALFO_RESPI_SYSTEM | 1.793 [1.51, 2.13] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.048 |
During the follow-up period (1.1.1998 — 31.12.2019), 306 out of 3120 males with Q17_CONGEN_MALFO_RESPI_SYSTEM died.
Mortality risk
Mortality risk for people of age
years, who have Q17_CONGEN_MALFO_RESPI_SYSTEM.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.152% | 0.304% |
| 5 | 0.981% | 2.075% |
| 10 | 2.571% | 5.326% |
| 15 | 4.954% | 10.257% |
| 20 | 8.949% | 16.892% |
Relationships between endpoints
↥Index endpoint: Q17_CONGEN_MALFO_RESPI_SYSTEM – Congenital malformations of the respiratory system
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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