No definition available.
Streptococcus and staphylococcus as the cause of diseases classified to other chapters
AB1_STREPTSTAPHYCOCC_INOTHER
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
250 |
4. Check minimum number of eventsNone |
250 |
5. Include endpointsNone |
250 |
6. Filter based on genotype QC (FinnGen only) |
217 |
Control definitions (FinnGen only)
- Control exclude
- AB1_BACT_BIR_OTHER_INF_AGENTS
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF5
Similar endpoints
↥List of similar endpoints to
Streptococcus and staphylococcus as the cause of diseases classified to other chapters
based on the number of shared cases.
Similar with more cases:
- Bacterial, viral and other infectious agents
- Bacterial, viral and other infectious agents, including avohilmo
- Certain infectious and parasitic diseases
- Certain infectious and parasitic diseases, including avohilmo
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2560 | 1085 | 1457 |
| Only index persons | 1924 | 822 | 1102 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.03 | 0.04 |
| Only index persons | 0.04 | 0.03 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 38.73 | 37.89 | 39.06 |
| Only index persons | 40.34 | 40.80 | 39.99 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 217 | 90 | 127 |
| Unadjusted period prevalence (%) | 0.05 | 0.03 | 0.06 |
| Median age at first event (years) | 57.16 | 54.83 | 58.82 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 225
- Matched controls
- 2250
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B95.6
ICD-10 Finland
Staphylococcus aureus as the cause of diseases classified to other chapters
+∞
88.5
79
*
B95.0
ICD-10 Finland
Streptococcus, group A, as the cause of diseases classified to other chapters
388.7
33.8
33
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
5.2
25.6
65
162
J01FF01
ATC
clindamycin; systemic
4.2
25.3
111
422
B95.4
ICD-10 Finland
Other streptococcus as the cause of diseases classified to other chapters
+∞
24.4
23
*
B95.7
ICD-10 Finland
Other staphylococcus as the cause of diseases classified to other chapters
+∞
23.3
22
*
A41.9
ICD-10 Finland
Sepsis, unspecified
8.8
23.1
31
40
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.4
21.4
39
71
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
60.6
19.3
22
*
B95.3
ICD-10 Finland
Streptococcus pneumoniae as the cause of diseases classified to other chapters
+∞
19.0
18
*
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
7.0
19.0
31
50
A46
ICD-10 Finland
Erysipelas
4.0
18.8
67
214
C03CA01
ATC
furosemide; systemic
3.4
18.5
109
483
ZXD05
NOMESCO Finland
Urgent procedure
3.4
18.3
105
457
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
15.7
17.9
29
21
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
5.3
17.3
39
86
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
4.5
17.0
48
128
J04AB02
ATC
rifampicin; systemic
30.3
16.9
22
8
B95.5
ICD-10 Finland
Unspecified streptococcus as the cause of diseases classified to other chapters
+∞
15.8
15
*
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
6.1
15.2
28
51
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
5.2
15.0
34
75
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
6.6
14.7
25
42
ZXE10
NOMESCO Finland
More than one and less than three hours
3.0
14.6
108
530
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.3
14.4
69
263
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
7.3
14.3
22
33
J01MA12
ATC
levofloxacin; systemic
3.3
14.2
67
253
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
3.1
13.4
74
306
XF400
NOMESCO Finland
ECG with 12 standard connections
3.3
13.3
61
225
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
5.2
13.2
29
62
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.5
13.1
55
192
TPH07
NOMESCO Finland
Cathetrisation of artery
3.6
12.1
45
145
R50.9
ICD-10 Finland
Fever, unspecified
3.2
12.0
59
226
Z2446
NOMESCO Finland
Social worker
4.3
11.9
33
86
B95.1
ICD-10 Finland
Streptococcus, group B, as the cause of diseases classified to other chapters
+∞
11.6
11
*
J01CF02
ATC
cloxacillin; systemic
11.5
11.5
21
20
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
13.7
11.4
19
15
TK800
NOMESCO Finland
Hemodialysis
12.8
11.1
19
16
127
Kela drug reimbursment
Transplant complication
16.6
11.0
17
11
WX408
NOMESCO Finland
General anesthesy, balanced
2.7
10.9
77
358
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
12.1
10.8
19
17
ZXD10
NOMESCO Finland
Scheduled procedure
2.5
10.6
106
583
Z49.1
ICD-10 Finland
Extracorporeal dialysis
34.3
10.4
13
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
9.9
10.3
20
22
J01MA02
ATC
ciprofloxacin; systemic
2.5
10.1
110
627
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.8
10.1
61
261
A10AC01
ATC
insulin (human); parenteral
3.6
10.0
37
118
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
57.5
9.7
11
*
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
5.0
9.5
21
45
Z94.0
ICD-10 Finland
Kidney transplant status
31.5
9.5
12
*
Z3226
NOMESCO Finland
Physiotherapist
2.8
9.5
60
262
L04AA01
ATC
[U] ciclosporin
22.9
9.5
13
6
B01AA03
ATC
warfarin; systemic
2.7
9.1
62
280
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
19.6
9.0
13
7
Z50.1
ICD-10 Finland
Other physical therapy
4.8
9.0
21
47
D64.9
ICD-10 Finland
Anaemia, unspecified
3.1
9.0
41
149
N18.8
ICD-10 Finland
Other chronic renal failure
10.1
8.9
17
18
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
4.6
8.9
22
52
ZXE00
NOMESCO Finland
One hour or less
2.3
8.8
106
621
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
7.5
8.8
20
29
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
52.1
8.7
10
*
WX892
NOMESCO Finland
Monitored bed care
3.7
8.7
29
86
TQW11
NOMESCO Finland
Vacuum treatment of wound
8.4
8.5
18
23
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.8
8.5
27
77
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.9
8.5
44
172
EBA15
NOMESCO Finland
Extraction of multiple teeth
7.0
8.4
20
31
ZXA00
NOMESCO Finland
Right side
2.4
8.2
74
381
QDB99
NOMESCO Finland
Other procedure for wound of skin of lower limb
34.7
8.1
10
*
R4110
NOMESCO Finland
Physiotherapy
2.3
8.1
82
444
Z3231
NOMESCO Finland
Registered nurse
2.3
8.1
83
452
201
Kela drug reimbursment
Chronic cardiac insufficiency
3.7
7.9
27
81
L04AD01
ATC
ciclosporin; systemic
11.4
7.9
14
13
A12AA04
ATC
calcium carbonate; oral
11.4
7.9
14
13
TPH04
NOMESCO Finland
Cathetrisation of vein
2.4
7.9
66
327
V03AE01
ATC
polystyrene sulfonate; oral
15.7
7.8
12
8
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
3.8
7.8
25
72
V03AE02
ATC
sevelamer; oral
46.6
7.8
9
*
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
7.1
7.8
18
27
WW200
NOMESCO Finland
Immunization
7.1
7.8
18
27
M46.4
ICD-10 Finland
Discitis, unspecified
19.2
7.7
11
6
A11CC03
ATC
alfacalcidol; systemic
7.6
7.6
17
24
J01MA14
ATC
moxifloxacin; systemic
3.2
7.6
33
116
ZXA05
NOMESCO Finland
Left side
2.4
7.6
70
362
J01CF05
ATC
flucloxacillin; systemic
3.3
7.5
30
100
B01AB05
ATC
enoxaparin; parenteral
2.2
7.5
83
464
B95.2
ICD-10 Finland
Streptococcus group D and enterococcus as the cause of diseases classified to other chapters
+∞
7.3
7
*
L04AX01
ATC
azathioprine; systemic
4.8
7.3
17
38
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
16.4
7.3
11
7
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
6.4
7.2
18
30
N18.0
ICD-10 Finland
End-stage renal disease
31.1
7.2
9
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.1
7.2
20
52
ZXE20
NOMESCO Finland
More than three and less than five hours
2.6
7.0
45
196
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.0
7.0
33
122
Z2221
NOMESCO Finland
Medical doctor
2.2
7.0
76
420
B99
ICD-10 Finland
Other and unspecified infectious diseases
7.6
6.8
15
21
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
41.3
6.8
8
*
I33.9
ICD-10 Finland
Acute endocarditis, unspecified
41.3
6.8
8
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.2
6.8
77
432
J01DA01
ATC
[U] cefalexin
2.1
6.7
148
1064
CKC12
NOMESCO Finland
Photocoagulation of retina
4.4
6.7
17
41
SPAT1255
SPAT
Intravenous administration of medicine
3.5
6.6
23
70
C09AA02
ATC
enalapril; systemic
2.3
6.6
57
285
Z94.1
ICD-10 Finland
Heart transplant status
71.8
6.5
7
*
WX002
NOMESCO Finland
Sedation and analgesia
2.4
6.4
54
266
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.7
6.4
36
146
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.8
6.4
35
140
L04AA06
ATC
mycophenolic acid; systemic
9.7
6.4
12
13
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
18.7
6.3
9
5
N17.9
ICD-10 Finland
Acute renal failure, unspecified
4.2
6.3
17
43
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
6.3
75
427
NHQ40
NOMESCO Finland
Amputation of toe
8.0
6.2
13
17
J01DB01
ATC
cefalexin; oral
2.6
6.2
192
1558
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.1
6.2
27
95
C07AB02
ATC
metoprolol; systemic
2.3
6.2
57
292
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
13.0
6.1
10
8
PD4CG
NOMESCO Finland
Extensive MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet
13.0
6.1
10
8
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.9
6.1
30
113
A10AB04
ATC
insulin lispro; parenteral
4.1
6.1
17
44
XW000
NOMESCO Finland
Bone marrow biopsy
4.1
6.1
17
44
M04AA01
ATC
allopurinol; systemic
2.5
6.1
42
189
B03XA02
ATC
darbepoetin alfa; parenteral
7.6
6.0
13
18
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
7.6
6.0
13
18
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
47
94
6.06
23.53
1.9
2.0
1.62
1.53
g/l
0.19
40
83
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
32
56
6.50
18.15
9.5
2.9
0.25
0.34
iu/ml
0.75
22
34
26
49
5.87
13.60
1.9
1.5
—
—
—
0
0
24
45
5.85
12.60
2.2
1.3
—
—
—
0
0
41
138
3.41
10.21
3.1
1.6
—
—
—
0
0
71
348
2.52
8.82
2.8
2.0
—
—
—
0
0
21
49
4.62
8.60
1.4
1.9
—
—
—
0
0
53
233
2.67
8.17
12.9
3.8
5.63
5.68
kpa
0.16
53
224
47
200
2.71
7.69
3.1
2.6
32.78
34.33
u/l
0.10
41
165
56
261
2.53
7.63
2.9
2.0
—
—
—
0
0
57
269
2.50
7.55
2.8
1.9
—
—
—
0
0
53
243
2.55
7.46
18.9
10.7
-1.16
0.84
mmol/l
1.74
44
206
46
197
2.68
7.42
4.7
3.4
—
—
—
0
0
96
572
2.18
7.36
5.4
3.2
0.66
0.46
e6/l
0.34
77
427
86
494
2.20
7.20
3.2
2.1
2.91
2.89
mg/l
0.03
78
435
41
168
2.76
7.19
2.2
2.3
64.42
66.55
g/l
0.85
41
157
23
67
3.71
7.05
3.7
3.1
2.40
2.47
ratio
0.02
16
38
63
328
2.28
6.62
7.1
2.0
31.81
29.08
s
2.60
63
322
21
62
3.63
6.31
1.9
1.3
—
—
—
0
0
17
43
4.19
6.29
1.8
1.3
—
—
—
0
0
17
43
4.19
6.29
1.8
1.3
—
—
—
0
0
31
123
2.76
5.75
2.4
1.7
—
—
—
0
0
126
888
1.95
5.66
5.6
3.0
144.76
125.80
ug/l
0.46
117
835
60
327
2.14
5.55
4.1
3.1
1.50
2.26
e6/l
0.48
31
171
42
200
2.35
5.35
25.0
8.3
1.12
1.36
mmol/l
1.31
42
195
16
44
3.84
5.31
2.2
1.2
—
—
—
0
0
151
1148
1.96
5.25
24.7
10.5
3.94
4.17
e9/l
0.68
141
992
18
55
3.47
5.15
5.2
2.7
3.00
2.26
index
0.19
12
31
140
1044
1.90
5.09
14.2
7.5
13.66
11.94
umol/l
0.42
135
989
10
13
7.99
4.90
1.4
1.2
157.45
175.35
iu/ml
—
10
13
57
319
2.05
4.86
1.8
1.7
1130.77
1260.34
nmol/l
0.41
44
247
121
870
1.85
4.85
20.6
7.7
1.19
1.21
mmol/l
1.20
109
808
13
26
5.24
4.71
1.2
1.3
—
—
—
0
0
15
43
3.67
4.70
2.3
1.1
260.56
259.00
u/ml
—
9
26
61
357
1.97
4.57
4.1
3.0
1.23
0.98
e6/l
0.24
34
199
15
44
3.58
4.55
3.2
1.5
—
—
—
0
0
72
453
1.87
4.32
5.4
2.6
—
—
—
0
0
9
13
7.16
4.20
1.6
2.0
—
—
—
0
0
9
13
7.16
4.20
1.6
2.0
—
—
—
0
0
19
69
2.92
4.13
2.1
1.5
—
—
—
0
0
64
396
1.86
4.01
7.8
4.1
374.98
347.62
ng/l
0.05
53
317
14
44
3.33
3.84
1.4
1.3
—
—
—
0
0
26
116
2.40
3.81
6.3
2.5
0.57
0.62
%
0.31
26
116
127
972
1.70
3.74
19.5
8.3
1.20
1.21
mmol/l
0.54
112
855
9
17
5.47
3.55
1.8
1.4
—
—
—
0
0
10
22
4.71
3.47
1.4
1.3
—
—
—
0
0
12
32
3.90
3.44
1.9
1.4
—
—
—
0
0
18
71
2.67
3.39
2.1
1.6
—
—
—
0
0
18
71
2.67
3.39
3.1
1.2
—
—
—
0
0
8
14
5.88
3.37
9.3
5.6
75.50
96.64
%
—
8
14
115
874
1.65
3.35
5.2
3.0
—
—
estimate
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
6
7
8.76
3.28
1.0
2.6
184.17
100.43
%
—
6
7
29
147
2.12
3.17
33.5
9.2
23.09
24.75
mmol/l
1.05
29
147
8
16
5.14
3.08
1.4
1.2
—
—
—
0
0
7
14
5.12
2.75
4.3
2.9
0.71
0.79
index
—
7
14
6
10
6.13
2.71
6.3
3.4
955.00
730.00
u/ml
—
6
10
29
492
0.53
2.66
3.1
3.2
1.73
0.75
ug/l
0.41
19
315
79
576
1.57
2.57
1.9
1.7
19.71
20.11
nmol/l
0.09
67
482
7
16
4.48
2.49
1.9
1.6
—
—
—
0
0
8
21
3.91
2.48
1.3
1.0
—
—
—
0
0
12
46
2.70
2.40
2.0
1.7
—
—
—
0
0
13
54
2.49
2.24
1.7
1.4
—
—
—
0
0
7
19
3.77
2.17
1.3
3.6
1003.43
740.84
mg
—
7
19
105
840
1.47
2.13
3.6
2.5
75.64
76.27
nmol/l
0.07
94
758
45
643
0.62
2.11
3.7
4.5
24.50
21.35
%
0.58
16
307
12
51
2.43
1.98
1.4
1.1
—
—
—
0
0
6
16
3.82
1.95
2.0
2.2
—
—
—
0
0
8
28
2.92
1.88
3.0
2.8
107.00
106.46
mmol/l
—
8
28
8
28
2.92
1.88
3.0
2.8
1.17
1.19
mmol/l
—
8
28
26
155
1.77
1.82
3.1
3.1
62.69
67.18
ml/min/173m2
0.19
13
68
9
35
2.64
1.82
1.4
1.1
—
—
—
0
0
13
60
2.24
1.81
1.6
1.4
—
—
—
0
0
170
1851
0.67
1.77
6.0
5.8
2.45
2.66
mmol/l
2.16
153
1722
18
96
1.95
1.76
4.9
9.5
2.12
1.54
%
0.88
18
89
104
853
1.41
1.75
2.6
2.1
81.30
96.26
pmol/l
3.20
59
458
14
69
2.10
1.68
2.6
2.9
—
—
—
0
0
8
31
2.64
1.67
2.8
1.5
—
—
—
0
0
6
19
3.21
1.67
1.2
1.7
—
—
—
0
0
11
49
2.31
1.66
1.5
1.1
—
—
—
0
0
164
1466
1.44
1.62
21.5
8.8
91.73
81.01
u/l
1.96
155
1391
5
14
3.63
1.62
1.2
1.3
—
—
—
0
0
8
32
2.55
1.61
1.5
1.9
—
—
—
0
0
7
27
2.64
1.52
2.6
2.1
—
—
—
0
0
13
66
2.03
1.46
2.6
2.0
—
—
—
0
0
20
119
1.75
1.43
9.1
3.8
0.52
2.29
mmol/l
0.54
13
85
57
434
1.42
1.43
5.1
1.8
2.17
1.49
mg/l
0.35
49
339
6
23
2.65
1.37
1.2
1.3
—
—
—
0
0
6
23
2.65
1.37
2.2
1.6
—
—
—
0
0
10
47
2.18
1.36
2.2
1.2
—
—
—
0
0
12
61
2.02
1.35
2.3
1.7
—
—
—
0
0
191
2013
0.66
1.33
61.5
25.5
126.58
136.61
g/l
11.81
191
1995
168
1810
0.72
1.32
5.2
5.1
1.32
1.41
mmol/l
2.06
148
1678
6
24
2.54
1.31
2.2
1.5
—
—
—
0
0
6
24
2.54
1.31
2.2
1.5
—
—
—
0
0
8
34
2.40
1.30
1.0
1.2
—
—
—
0
0
79
645
1.35
1.29
7.4
3.1
2.33
2.35
mmol/l
0.88
74
578
15
85
1.82
1.26
1.4
1.3
—
—
—
0
0
164
1770
0.73
1.26
5.1
5.2
6.26
5.99
mmol/l
1.24
150
1633
8
36
2.27
1.25
1.0
1.2
—
—
—
0
0
169
1815
0.72
1.25
5.5
5.2
4.31
4.52
mmol/l
1.93
152
1693
12
211
0.54
1.24
3.8
5.0
24.50
31.41
%
—
6
127
10
49
2.09
1.24
1.4
1.5
—
—
—
0
0
6
26
2.34
1.19
2.0
1.7
—
—
—
0
0
6
26
2.34
1.19
2.0
1.7
—
—
—
0
0
6
26
2.34
1.19
2.0
1.7
—
—
—
0
0
7
30
2.37
1.13
1.6
1.9
—
—
—
0
0
120
1056
1.29
1.11
4.6
3.9
0.00
0.00
estimate
-0.00
24
217
11
59
1.91
1.09
1.1
1.3
—
—
—
0
0
160
1720
0.76
1.05
4.7
4.4
1.39
1.28
mmol/l
0.98
141
1585
67
801
0.77
1.02
5.1
5.4
2.78
2.35
ug/l
0.11
58
720
166
1773
0.76
1.01
40.3
16.4
78.10
81.67
ml/min/173m2
1.00
155
1639
5
23
2.20
0.98
2.4
1.6
—
—
—
0
0
5
23
2.20
0.98
2.4
1.6
—
—
—
0
0
186
1953
0.73
0.98
27.5
12.5
28.64
26.64
u/l
0.88
181
1901
120
1067
1.27
0.98
4.7
3.9
0.00
0.00
estimate
-0.00
25
220
120
1075
1.25
0.89
5.0
3.9
0.00
0.02
estimate
0.50
24
204
16
105
1.56
0.84
1.3
1.4
—
—
—
0
0
164
1736
0.80
0.76
8.4
6.6
41.77
39.76
mmol/mol
1.33
152
1634
5
24
2.11
0.75
2.4
1.5
—
—
—
0
0
5
24
2.11
0.75
1.6
1.2
—
—
—
0
0
9
55
1.66
0.74
1.0
1.1
—
3.60
—
0
9
17
118
1.48
0.71
1.1
1.4
81.79
116.60
u/ml
—
8
44
7
42
1.69
0.69
6.4
1.8
0.57
0.77
nmol/l
—
7
36
8
49
1.66
0.63
1.5
1.6
—
—
—
0
0
0
23
0.00
0.58
0.0
3.7
—
23.87
—
0
13
54
463
1.22
0.58
1.4
1.3
0.70
1.40
u/ml
—
8
116
6
40
1.51
0.52
1.8
1.5
—
—
—
0
0
126
1176
1.16
0.50
3.5
3.2
—
—
—
0
0
7
48
1.47
0.47
1.9
1.5
—
—
—
0
0
46
398
1.20
0.46
1.9
1.8
421.13
442.72
pmol/l
0.14
40
347
25
202
1.27
0.46
1.5
1.5
—
—
—
0
0
25
202
1.27
0.46
3.3
1.9
—
—
—
0
0
5
33
1.53
0.41
7.4
2.5
10.80
9.57
pmol/l
—
5
33
5
33
1.53
0.41
9.0
2.0
11.80
10.97
mmol/l
—
5
33
0
15
0.00
0.41
0.0
2.5
—
13.31
—
0
15
71
643
1.15
0.41
7.0
4.1
33.30
9.12
mg/mmol
1.16
51
421
5
34
1.48
0.40
1.6
1.4
1.40
0.99
ratio
—
5
18
5
34
1.48
0.40
1.6
1.4
0.99
1.45
ratio
—
5
18
5
34
1.48
0.40
1.6
1.4
0.85
1.36
ratio
—
5
18
21
170
1.26
0.39
6.1
3.1
0.04
0.70
e6/l
0.71
21
163
5
37
1.36
0.37
1.6
1.6
45.24
68.98
ug/l
—
5
30
5
78
0.63
0.36
1.6
1.7
129.60
247.27
pmol/l
—
5
70
53
583
0.88
0.31
5.2
3.5
0.00
0.00
estimate
-0.00
19
173
27
233
1.18
0.29
1.4
1.8
1.77
1.56
%
0.59
21
207
17
203
0.82
0.27
14.4
8.0
—
—
—
0
0
144
1388
1.10
0.27
4.5
4.2
14.53
14.81
pmol/l
0.62
133
1267
5
72
0.69
0.26
1.0
1.7
11.98
3.17
mg/l
—
5
55
13
159
0.81
0.25
1.6
1.4
—
—
—
0
0
75
798
0.91
0.24
2.1
2.0
1.47
1.32
mmol/l
0.37
63
675
0
10
0.00
0.21
0.0
1.4
—
11.10
—
0
10
25
221
1.15
0.21
3.6
2.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
5.2
—
90.69
—
0
14
6
50
1.21
0.20
1.0
1.2
—
4.80
—
0
5
37
338
1.11
0.19
1.2
1.4
3.51
7.91
u/ml
0.72
18
130
15
130
1.16
0.16
1.3
1.3
—
23.96
—
0
10
9
81
1.12
0.15
5.4
2.0
—
—
—
0
0
166
1688
0.94
0.13
5.7
5.2
1.96
1.93
mu/l
0.13
153
1553
38
357
1.08
0.12
1.8
1.6
—
—
—
0
0
146
1433
1.05
0.11
8.0
4.4
16.05
11.33
mm/h
2.64
136
1325
77
795
0.95
0.10
4.6
3.9
0.11
0.02
estimate
0.35
19
184
56
582
0.95
0.09
4.2
3.9
0.00
0.01
estimate
0.74
21
201
186
1841
1.06
0.08
47.3
17.2
29.56
24.28
mg/l
1.62
171
1508
7
64
1.10
0.08
1.0
1.2
—
—
—
0
0
6
71
0.84
0.08
2.0
1.5
—
—
—
0
0
10
89
1.13
0.07
1.1
1.1
—
—
—
0
0
10
92
1.09
0.03
1.3
1.8
58.70
40.39
nmol/l
—
10
87
11
102
1.08
0.03
5.0
2.1
—
—
—
0
0
45
455
0.99
0.00
3.4
4.2
1.02
1.02
kg/l
0.08
33
310
37
365
1.02
0.00
1.3
1.3
18.53
32.46
iu/ml
—
10
117
130
1305
0.99
0.00
5.1
3.6
80.42
49.93
u/l
1.52
121
1232
0
9
0.00
-0.00
0.0
1.0
—
31.47
—
0
9
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
54
0.92
-0.00
1.4
1.5
—
315.92
—
0
26
0
7
0.00
-0.00
0.0
1.0
—
42.84
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
78
780
1.00
-0.00
4.3
4.1
37.28
41.04
ng/l
0.14
58
563
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint AB1_STREPTSTAPHYCOCC_INOTHER and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_STREPTSTAPHYCOCC_INOTHER | 2.548 [1.94, 3.35] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.489 |
During the follow-up period (1.1.1998 — 31.12.2019), 185 out of 872 females with AB1_STREPTSTAPHYCOCC_INOTHER died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_STREPTSTAPHYCOCC_INOTHER | 3.059 [2.4, 3.9] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 310 out of 1147 males with AB1_STREPTSTAPHYCOCC_INOTHER died.
Mortality risk
Mortality risk for people of age
years, who have AB1_STREPTSTAPHYCOCC_INOTHER.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.3% | 0.628% |
| 5 | 1.742% | 3.201% |
| 10 | 4.149% | 8.239% |
| 15 | 7.55% | 15.117% |
| 20 | 13.582% | 24.671% |
Relationships between endpoints
↥Index endpoint: AB1_STREPTSTAPHYCOCC_INOTHER – Streptococcus and staphylococcus as the cause of diseases classified to other chapters
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data