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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Toxic colitis

COLITTOX

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K52.1
  • Cause of death: ICD-10 K52.1

2 out of 7 registries used, show all original rules.

141

4. Check minimum number of events

None

141

5. Include endpoints

None

141

6. Filter based on genotype QC (FinnGen only)

125

Control definitions (FinnGen only)

Control exclude
K11_ENERCOLNONINF

Extra metadata

First used in FinnGen datafreeze
DF2
Parent code in ICD-10
K52
Name in latin
Gastroenteritis toxica

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 125 70 55
Unadjusted period prevalence (%) 0.03 0.02 0.03
Median age at first event (years) 60.64 54.32 68.69

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
129
Matched controls
1290
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K52.1
ICD-10 Finland
Toxic gastroenteritis and colitis
+∞
186.3
129
*
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
+∞
24.8
23
*
A07EC02
ATC
mesalazine; oral, rectal
67.5
24.1
27
5
UJF32
NOMESCO Finland
Coloscopy
5.8
22.0
64
188
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
58.4
21.0
24
5
A03FA01
ATC
metoclopramide; systemic, rectal
5.5
20.5
63
192
A04AA02
ATC
granisetron; systemic, transdermal
8.2
19.7
30
46
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
8.4
19.1
28
41
JN4BD
NOMESCO Finland
Extensive body CT
6.3
17.6
36
75
H02AB02
ATC
dexamethasone; systemic
5.5
16.4
40
98
K51.5
ICD-10 Finland
Left sided colitis
+∞
16.0
15
*
JN4AD
NOMESCO Finland
Body CT examination
5.5
15.6
37
88
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
7.8
15.0
23
35
K51.2
ICD-10 Finland
Ulcerative (chronic) proctitis
+∞
14.9
14
*
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
+∞
14.9
14
*
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
+∞
14.9
14
*
130
Kela drug reimbursment
Malignant tumour
5.6
14.8
33
74
A49.9
ICD-10 Finland
Bacterial infection, unspecified
5.3
13.7
33
79
R11
ICD-10 Finland
Nausea and vomiting
5.7
13.6
29
62
ZX120
NOMESCO Finland
Intravenous
5.7
13.6
29
62
UJF30
NOMESCO Finland
Ileoscopy through colon
6.0
13.1
26
52
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.9
13.0
58
222
A04AA01
ATC
ondansetron; systemic, rectal
5.7
12.3
26
55
Z51.5
ICD-10 Finland
Palliative care
5.3
12.1
28
64
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
4.0
11.6
43
143
N02AA05
ATC
oxycodone; systemic
3.9
11.5
47
167
JN3AD
NOMESCO Finland
Abdominal CT examination
4.5
11.2
33
92
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
9.4
11.2
23
29
A07EA06
ATC
budesonide; oral, local oral
24.0
11.0
15
7
L01BC06
ATC
capecitabine; oral
9.6
10.9
22
27
H02AB06
ATC
prednisolone; systemic
3.4
10.2
85
465
A07EA02
ATC
hydrocortisone; rectal
43.8
10.2
12
*
A02BC02
ATC
pantoprazole; systemic
4.2
9.4
107
696
L04AX01
ATC
azathioprine; systemic
17.2
9.3
14
9
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.0
8.7
29
88
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
8.1
8.6
19
27
P01AB01
ATC
metronidazole; oral, rectal
3.0
8.5
68
352
N02AX02
ATC
tramadol; systemic, rectal
2.9
8.1
71
384
WZC00
NOMESCO Finland
Treatment plan or consultation
2.9
8.0
66
345
UGC12
NOMESCO Finland
Flexible bronchoscopy
4.9
8.0
19
44
TPH04
NOMESCO Finland
Cathetrisation of vein
3.2
7.9
41
165
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
7.7
7.6
17
25
K51
ICD-10 Finland
Ulcerative colitis
+∞
7.4
7
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.9
7.1
23
68
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.7
7.0
76
449
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.2
6.9
20
54
B01AB05
ATC
enoxaparin; parenteral
2.6
6.5
53
270
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
7.7
6.4
14
20
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
19.2
6.4
9
5
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.0
6.1
32
128
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.8
6.1
39
174
TPX10
NOMESCO Finland
Implantation of vascular injection port
7.0
6.1
14
22

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
30
57
6.56
16.02
1.3
1.3
—
—
—
0
0
71
310
3.87
13.10
8.0
4.3
—
—
—
0
0
92
489
4.07
12.43
13.2
4.8
33.26
36.15
g/l
3.58
92
470
38
114
4.31
11.81
1.6
1.2
—
—
—
0
0
53
204
3.71
11.55
8.8
3.0
0.79
0.82
mmol/l
1.37
53
193
106
652
4.51
10.90
26.3
10.3
4.20
4.04
e9/l
0.33
98
568
75
379
3.34
10.32
13.9
5.4
—
—
—
0
0
31
94
4.02
9.34
1.5
1.4
—
—
—
0
0
98
608
3.55
9.12
21.6
6.7
10.53
11.36
umol/l
0.41
98
581
91
543
3.29
8.99
13.7
6.0
24.84
27.02
%
1.18
91
519
97
602
3.46
8.94
13.8
6.3
0.17
0.19
e9/l
0.91
85
523
95
583
3.39
8.91
13.4
6.1
0.62
0.59
e9/l
0.63
82
501
95
584
3.38
8.86
13.4
6.1
0.04
0.04
e9/l
0.18
82
501
96
594
3.41
8.85
13.3
6.1
1.71
1.81
e9/l
0.53
85
523
19
31
7.00
7.91
2.2
1.3
211.00
293.02
ug/g
0.90
14
13
38
147
3.25
7.85
1.3
1.2
—
—
—
0
0
41
168
3.11
7.67
3.9
1.9
—
—
—
0
0
88
555
2.84
7.15
13.4
7.3
1.19
1.21
mmol/l
2.31
81
488
39
164
2.98
6.90
9.9
6.5
104.46
104.54
mmol/l
0.04
39
164
37
153
2.99
6.73
9.6
6.8
1.03
1.05
mmol/l
0.14
37
138
81
502
2.65
6.61
12.0
6.2
1.19
1.22
mmol/l
2.38
81
471
63
353
2.53
6.26
8.0
4.2
7.40
7.40
ph
0.35
50
251
55
289
2.57
6.25
2.6
2.1
2.88
2.71
mg/l
0.24
50
256
60
329
2.54
6.23
4.0
3.1
—
—
—
0
0
31
121
3.06
6.20
5.6
4.0
7.37
7.38
ph
0.70
20
68
31
121
3.06
6.20
5.5
4.1
5.80
5.82
kpa
0.04
31
116
27
103
3.05
5.58
5.3
5.3
2.37
0.88
%
0.74
19
33
60
347
2.36
5.36
17.9
6.2
—
—
—
0
0
29
125
2.70
4.78
4.1
2.2
38.72
27.97
u/l
0.96
29
100
42
217
2.39
4.75
6.0
3.7
42.00
243.38
ng/l
0.85
32
164
76
508
2.21
4.58
23.3
12.3
1.25
1.22
inr
0.24
69
419
64
400
2.19
4.57
4.8
3.2
19.59
32.63
e6/l
0.75
57
305
10
15
7.12
4.56
2.2
1.5
19.50
20.97
ng/l
—
10
15
25
102
2.80
4.56
7.8
7.9
—
—
—
0
0
38
192
2.39
4.49
4.4
2.8
2.23
2.18
e6/l
0.02
26
94
30
136
2.57
4.46
1.6
1.6
—
—
—
0
0
68
443
2.13
4.29
6.5
3.9
71.04
50.16
e6/l
0.33
59
317
19
71
2.97
4.03
7.7
5.4
23.64
25.31
mmol/l
0.84
19
71
75
517
2.08
3.97
5.0
2.7
—
—
estimate
—
0
0
24
103
2.63
3.96
4.2
3.0
3.73
4.56
kpa
2.61
24
98
23
98
2.64
3.84
5.7
5.4
0.13
0.18
%
0.14
15
28
39
212
2.20
3.83
1.7
2.0
—
—
—
0
0
28
132
2.43
3.81
2.9
1.3
—
—
—
0
0
74
513
2.04
3.80
27.5
11.3
0.00
0.00
e9/l
-0.00
60
411
16
56
3.12
3.78
5.2
2.5
—
—
—
0
0
71
487
2.02
3.73
4.4
3.7
6.35
6.23
ph
0.43
40
264
8
12
7.02
3.73
3.7
3.8
3.09
3.67
nmol/l
—
8
12
27
127
2.42
3.69
9.5
7.9
7.41
7.41
ph
0.06
15
76
55
348
2.01
3.59
5.1
3.1
0.83
0.43
e6/l
0.30
49
254
10
23
4.62
3.39
3.4
2.5
—
—
—
0
0
22
98
2.50
3.36
5.3
5.4
0.89
0.79
%
0.07
14
29
54
347
1.96
3.33
3.9
3.8
0.00
0.00
estimate
-0.00
21
117
24
112
2.40
3.32
4.3
3.5
79.94
73.55
e9/l
0.27
16
84
44
265
2.00
3.25
3.4
4.0
1.02
1.02
kg/l
0.02
31
163
82
611
1.94
3.20
5.3
4.1
0.00
0.00
estimate
-0.00
23
128
17
69
2.69
3.11
3.8
2.8
0.70
0.66
%
0.33
17
69
17
69
2.69
3.11
3.8
2.8
1.14
1.21
%
0.17
17
69
81
605
1.91
3.09
5.2
4.1
0.00
0.00
estimate
-0.00
22
128
63
435
1.88
3.07
3.0
2.1
—
—
—
0
0
51
330
1.90
3.02
5.0
3.0
—
—
estimate
—
0
0
11
32
3.66
2.98
1.2
1.1
—
—
—
0
0
82
622
1.87
2.91
5.3
4.1
0.00
2.40
estimate
0.50
21
125
19
87
2.39
2.73
1.3
1.4
—
—
—
0
0
32
185
1.97
2.60
1.6
1.7
—
—
—
0
0
53
361
1.79
2.60
4.8
2.3
—
—
—
0
0
5
7
7.37
2.57
4.4
4.6
75.20
115.14
nmol/l
—
5
7
24
125
2.13
2.57
2.7
1.6
—
—
—
0
0
7
16
4.56
2.51
1.3
1.4
305.43
246.67
u/ml
—
7
6
20
99
2.21
2.42
5.8
5.9
0.00
0.11
%
0.73
12
27
7
17
4.29
2.39
3.7
2.1
—
—
—
0
0
6
13
4.78
2.30
5.2
3.4
—
—
—
0
0
40
259
1.79
2.28
6.7
5.7
—
—
—
0
0
5
9
5.73
2.23
1.0
1.0
—
—
—
0
0
5
9
5.73
2.23
1.0
1.4
—
—
—
0
0
63
469
1.67
2.15
4.4
3.9
0.00
0.00
estimate
-0.00
20
113
12
50
2.54
2.09
7.2
4.4
36.84
36.93
°c
0.27
12
50
5
10
5.15
2.09
1.4
1.4
—
—
—
0
0
5
10
5.15
2.09
1.6
1.8
—
—
—
0
0
5
10
5.15
2.09
1.2
1.4
—
—
—
0
0
18
91
2.14
2.07
2.3
2.4
0.64
1.16
e6/l
0.21
18
85
119
1071
2.43
2.02
45.5
15.6
25.68
22.81
mg/l
0.52
113
882
7
21
3.46
1.99
5.6
2.0
7.87
8.59
kpa
—
7
21
16
79
2.17
1.95
1.8
2.2
—
—
—
0
0
6
17
3.65
1.86
3.0
1.4
—
—
—
0
0
6
17
3.65
1.86
3.0
1.4
—
—
—
0
0
6
17
3.65
1.86
3.0
1.4
—
—
—
0
0
6
17
3.65
1.86
3.0
1.4
—
—
—
0
0
8
30
2.77
1.75
1.3
1.5
—
—
—
0
0
5
13
3.95
1.73
3.2
1.2
21.08
13.54
ug/l
—
5
13
45
323
1.60
1.70
1.4
1.5
—
—
—
0
0
6
19
3.26
1.68
1.5
1.4
—
—
—
0
0
5
14
3.67
1.63
2.8
3.7
27.20
123.98
u/ml
—
5
14
14
71
2.09
1.61
6.4
4.7
—
—
—
0
0
64
506
1.53
1.56
2.3
2.0
94.56
98.32
pmol/l
0.30
41
263
16
87
1.96
1.54
4.6
3.8
—
—
—
0
0
7
27
2.68
1.54
2.4
1.2
—
—
—
0
0
6
21
2.94
1.52
5.8
2.0
5.12
5.00
kpa
—
6
21
9
37
2.54
1.51
5.6
2.4
1.38
1.45
mg/l
—
9
31
104
920
1.67
1.50
51.8
19.7
14.49
13.60
%
7.14
104
915
6
22
2.81
1.45
3.0
3.4
14.33
47.84
u/ml
—
6
22
31
429
0.63
1.38
3.3
3.5
—
—
—
0
0
57
451
1.47
1.33
4.8
3.9
23.90
41.34
ng/l
1.04
45
324
34
243
1.54
1.28
1.9
1.7
2.48
1.56
mg/l
0.50
28
200
118
1095
1.91
1.24
45.1
18.1
138.91
139.86
mmol/l
3.46
118
1076
118
1096
1.90
1.22
45.7
18.3
3.96
3.97
mmol/l
0.09
118
1074
8
38
2.18
1.21
2.0
3.3
—
—
—
0
0
13
72
1.90
1.20
3.0
1.5
1.25
1.07
g/l
0.33
13
66
23
152
1.62
1.19
1.3
1.2
—
—
—
0
0
5
20
2.56
1.16
3.0
3.0
1.42
0.91
%
—
5
14
12
66
1.90
1.13
3.8
3.5
4.36
4.46
pmol/l
0.21
12
60
7
31
2.33
1.12
2.0
1.5
43.37
10.62
mg/l
—
7
31
5
22
2.32
1.04
3.6
2.5
12.36
16.50
%
—
5
22
120
1138
1.78
0.96
51.9
20.2
80.77
78.80
umol/l
0.15
120
1129
6
28
2.20
0.93
3.5
2.2
6.30
8.04
kpa
—
6
28
47
388
1.33
0.79
2.9
3.3
7.36
7.94
mmol/l
0.39
39
330
40
323
1.35
0.77
5.5
3.5
—
0.00
—
0
6
6
34
1.80
0.77
6.0
2.5
7.43
7.42
ph
—
6
34
5
23
2.22
0.77
3.4
2.3
78.10
90.07
%
—
5
23
42
342
1.34
0.77
4.2
3.5
0.05
0.24
estimate
0.35
19
104
108
1010
1.43
0.73
6.5
5.4
1.91
1.90
mu/l
0.04
101
935
5
26
1.96
0.71
8.8
2.8
67.40
62.67
%
—
5
26
5
27
1.89
0.69
1.6
2.5
44.94
57.82
%
—
5
27
14
198
0.67
0.66
1.4
1.4
1.38
7.81
u/ml
—
6
76
100
1061
0.74
0.64
5.0
5.2
1.34
1.47
mmol/l
2.57
88
982
5
29
1.75
0.64
2.8
1.1
—
80.00
—
0
6
8
49
1.67
0.63
3.8
3.6
—
—
—
0
0
0
20
0.00
0.61
0.0
2.0
—
—
—
0
0
6
35
1.75
0.58
1.3
1.3
14.05
8.67
u/l
—
6
28
44
375
1.26
0.56
4.2
3.7
—
—
—
0
0
95
1009
0.78
0.55
4.6
4.4
1.75
1.29
mmol/l
0.75
84
927
44
380
1.24
0.50
3.9
4.1
4.37
10.18
mg/mmol
1.62
30
246
7
49
1.45
0.47
2.1
1.1
—
—
—
0
0
5
32
1.58
0.42
1.0
1.3
—
—
—
0
0
5
33
1.54
0.42
4.6
5.8
—
—
—
0
0
102
1065
0.80
0.41
5.0
5.3
4.46
4.63
mmol/l
0.48
90
994
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
104
1083
0.80
0.40
5.6
6.0
2.48
2.71
mmol/l
1.77
92
1006
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
120
1167
1.41
0.37
63.5
24.1
127.37
135.23
g/l
6.58
120
1160
9
123
0.71
0.37
2.0
1.7
—
—
—
0
0
120
1166
1.42
0.37
62.2
23.9
91.46
91.13
fl
0.33
120
1160
120
1166
1.42
0.37
63.5
24.4
38.49
40.41
%
5.21
120
1158
120
1166
1.42
0.37
62.1
23.9
30.31
30.34
pg
0.05
120
1160
7
56
1.26
0.30
1.1
1.1
—
—
—
0
0
30
263
1.18
0.29
1.5
1.3
7.84
0.84
u/ml
—
10
66
41
372
1.15
0.26
3.1
3.4
20.43
64.85
mg/l
2.55
29
247
11
87
1.29
0.25
7.4
4.4
7.31
7.34
ph
0.13
11
63
5
38
1.33
0.23
1.0
1.2
1.04
0.91
g/l
—
5
38
5
38
1.33
0.23
1.0
1.2
1.71
1.60
g/l
—
5
38
19
163
1.19
0.23
2.1
1.4
373.33
586.05
titre
—
9
43
5
40
1.26
0.22
12.0
8.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
321.14
—
0
7
6
51
1.18
0.19
1.5
1.5
31.15
23.21
iu/l
—
6
42
5
69
0.71
0.17
1.2
1.3
—
44.06
—
0
5
8
71
1.14
0.16
1.0
1.2
—
—
—
0
0
11
93
1.20
0.15
9.5
4.0
1.22
1.22
mmol/l
0.17
11
81
12
104
1.17
0.13
1.8
1.7
—
—
—
0
0
22
240
0.90
0.12
2.7
3.1
0.83
0.76
ug/l
0.13
15
159
14
126
1.12
0.09
1.9
1.7
—
—
—
0
0
6
54
1.12
0.09
2.8
1.9
—
—
—
0
0
112
1107
1.09
0.07
36.0
14.1
—
—
—
0
0
10
94
1.07
0.01
1.2
1.2
—
—
—
0
0
105
1044
1.03
0.00
5.6
5.1
6.34
5.93
mmol/l
1.80
96
965
10
97
1.03
0.00
1.6
2.2
6.38
13.57
nmol/l
—
10
91
11
105
1.05
0.00
2.3
1.5
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
98.43
—
0
9
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
42.12
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
41.17
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
227.47
—
0
8
0
6
0.00
-0.00
0.0
1.2
—
306.17
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
1.08
—
0
5
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
92
0.98
-0.00
1.1
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
59.83
—
0
6
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
161.50
—
0
6

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: COLITTOX – Toxic colitis

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).