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Osteopathy in diseases classified elsewhere

DOID Endpoint Browser PheWeb

M13_OSTEOPATHYINOTH

musculoskeletal system disease: A disease involving the musculoskeletal system. [database_cross_reference: MONDO:DesignPattern]

Suggest a new description

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

380

4. Check minimum number of events

None

380

5. Include endpoints

None

380

6. Filter based on genotype QC (FinnGen only)

268

Control definitions (FinnGen only)

Control exclude
M13_OSTEOCHONDRO

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1723 895 807
Only index persons 1430 752 678
Unadjusted period prevalence (%)
Whole population 0.02 0.03 0.02
Only index persons 0.03 0.03 0.03
Median age at first event (years)
Whole population 67.00 67.82 66.10
Only index persons 66.54 67.84 65.10

-FinnGen-

Key figures

All Female Male
Number of individuals 268 146 122
Unadjusted period prevalence (%) 0.05 0.05 0.06
Median age at first event (years) 66.79 65.37 68.48

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
280
Matched controls
2800
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
WF049
NOMESCO Finland
Radiotherapy of metastasis
46.6
191.2
124
47
M90.7*C90.0
ICD-10 Finland
Pathological fracture in multiple myeloma
+∞
147.3
128
*
C90.0
ICD-10 Finland
Multiple myeloma
89.7
146.0
78
12
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
47.1
131.9
81
24
N02AA05
ATC
oxycodone; systemic
16.2
126.2
192
333
H02AB02
ATC
dexamethasone; systemic
14.8
118.1
152
208
WF004
NOMESCO Finland
Palliative radiotherapy
50.5
115.6
69
18
NF3AA
NOMESCO Finland
Femur X-ray examination
48.6
111.3
67
18
M05BX04
ATC
denosumab; parenteral
19.3
99.3
88
65
A04AA01
ATC
ondansetron; systemic, rectal
12.0
79.6
98
120
L03AA02
ATC
filgrastim; parenteral
19.8
78.6
66
43
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
15.9
77.9
75
63
Z51.5
ICD-10 Finland
Palliative care
10.5
75.3
106
154
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
15.4
69.4
67
56
NE1AA
NOMESCO Finland
Pelvis X-ray examination
10.4
67.5
91
124
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
13.4
62.8
66
63
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
10.9
58.5
72
86
NFB60
NOMESCO Finland
Demanding prosthetic replacement of hip
242.6
58.5
58
*
M90.7
ICD-10 Finland
Fracture of bone in neoplastic disease
+∞
55.0
51
*
153
Kela drug reimbursment
Lenalidomid
113.6
52.0
55
6
B03XA02
ATC
darbepoetin alfa; parenteral
20.7
51.7
41
23
9732/3-C42.1
ICD-O-3
Plasma cell myeloma of bone marrow
86.9
51.3
56
8
L04AX04
ATC
lenalidomide; oral
111.1
50.9
54
6
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
6.2
49.6
188
692
A03FA01
ATC
metoclopramide; systemic, rectal
5.6
45.3
139
421
WX212
NOMESCO Finland
Femoral plexus blockade
18.2
45.2
38
24
JN4AD
NOMESCO Finland
Body CT examination
6.5
44.2
92
196
A49.9
ICD-10 Finland
Bacterial infection, unspecified
6.6
44.1
90
188
M84.4
ICD-10 Finland
Pathological fracture, not elsewhere classified
+∞
42.8
40
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
15.7
39.8
36
26
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
16.5
39.8
35
24
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
8.4
38.4
56
81
XW000
NOMESCO Finland
Bone marrow biopsy
10.4
38.3
46
52
B01AB10
ATC
tinzaparin; parenteral
5.9
37.7
85
193
WW500
NOMESCO Finland
Blood transfusion
9.7
37.1
47
57
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
9.3
36.5
48
61
NFR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of hip or thigh
87.3
34.8
38
5
JN4BD
NOMESCO Finland
Extensive body CT
5.8
34.8
78
175
329
Kela drug reimbursment
Lenalidomide
106.2
34.7
37
*
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
14.3
33.7
32
25
ZX112
NOMESCO Finland
Subcutaneous
13.2
33.1
33
28
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
13.8
32.9
32
26
A79
ICPC
Malignancy NOS
14.4
32.8
31
24
NB6AA
NOMESCO Finland
Humerus X-ray examination
12.8
31.5
32
28
XX3DW
NOMESCO Finland
Time consuming IT work
5.3
30.6
76
185
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
6.5
30.2
56
104
ZX120
NOMESCO Finland
Intravenous
5.4
28.8
68
158
C03CA01
ATC
furosemide; systemic
3.9
27.8
146
616
B01AB05
ATC
enoxaparin; parenteral
3.8
27.4
147
627
M04AA01
ATC
allopurinol; systemic
4.6
27.1
82
233
130
Kela drug reimbursment
Malignant tumour
5.2
26.2
63
148
NFJ60
NOMESCO Finland
Internal fixation of fracture of other parts of femur with intramedullary nail
103.3
26.2
28
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
5.8
25.6
53
109
M90.8*N25.0
ICD-10 Finland
Osteopathy in renal osteodystrophy
+∞
25.4
24
*
TPH04
NOMESCO Finland
Cathetrisation of vein
3.8
24.7
109
403
TPX10
NOMESCO Finland
Implantation of vascular injection port
9.3
24.5
31
37
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
24.0
24.1
34
16
YN7BD
NOMESCO Finland
Extensive CT examination of spine for dose design of radiotherapy
261.4
24.0
24
*
L04AX06
ATC
pomalidomide; oral
136.7
24.0
25
*
ZXD05
NOMESCO Finland
Urgent procedure
3.6
24.0
130
548
L03AA13
ATC
pegfilgrastim; parenteral
6.5
23.2
41
72
393
Kela drug reimbursment
Pomalidomide
91.2
23.1
25
*
J01MA12
ATC
levofloxacin; systemic
3.8
23.0
92
317
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
35.7
22.9
29
9
A04AA02
ATC
granisetron; systemic, transdermal
5.3
22.3
50
110
WW300
NOMESCO Finland
Transfer of autologic stem cells
68.3
22.2
25
*
M907, C6488,
ICD-10 Finland
+∞
22.2
21
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
8.9
22.2
29
36
NBJ60
NOMESCO Finland
Internal fixation of fracture of shoulder or upper arm using intramedullary nail, humerus
124.8
21.9
23
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
5.9
21.8
43
84
NF1AA
NOMESCO Finland
Hip X-ray examination
4.7
21.3
57
145
ZX090
NOMESCO Finland
Other technic of radiotherapy
8.1
21.2
30
41
WZC00
NOMESCO Finland
Treatment plan or consultation
3.2
21.0
145
696
L02BA03
ATC
fulvestrant; parenteral
35.6
20.6
26
8
WF002
NOMESCO Finland
Radical radiotherapy
5.8
20.5
41
81
A06AH03
ATC
naloxegol; oral
25.8
20.4
28
12
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
6.2
20.2
37
67
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
5.7
19.7
40
80
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.5
19.6
87
317
R4110
NOMESCO Finland
Physiotherapy
3.2
19.5
122
547
ZX080
NOMESCO Finland
Image guided radiotherapy
8.6
19.5
26
33
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
59.4
19.2
22
*
A28
ICPC
Limited function/disability NOS
3.5
19.0
87
323
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.1
18.7
182
1041
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.5
18.7
81
290
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.6
18.3
76
264
192
Kela drug reimbursment
Fulvestrant
56.5
18.2
21
*
TPH07
NOMESCO Finland
Cathetrisation of artery
3.9
18.1
62
189
1507
Kela drug reimbursment
Pomalidomide
71.4
18.0
20
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
15.3
17.7
29
21
X59
ICD-10 Finland
Exposure to unspecified factor
3.4
17.7
84
317
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.8
17.5
62
193
JN4CD
NOMESCO Finland
Very extensive body CT
6.5
17.4
30
51
NJ3DA
NOMESCO Finland
Long bones of extremities X-ray examination
37.6
16.9
21
6
WD515
NOMESCO Finland
Demanding therapy of malignancy with enzyme inhibitors and similar treatments
42.9
16.6
20
5
C64
ICD-10 Finland
Malignant neoplasm of kidney, except renal pelvis
22.6
16.3
23
11
197
Kela drug reimbursment
Sunitinib
63.8
16.0
18
*
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
7.7
15.9
23
32
WX402
NOMESCO Finland
General anaesthesia
3.0
15.9
97
421
YN1BD
NOMESCO Finland
Extensive CT examination of extremities for dose design of radiotherapy
+∞
15.8
15
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.8
15.7
138
727
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
4.0
15.4
49
141
115
Kela drug reimbursment
Breast cancer
4.0
15.4
50
146
S72.3
ICD-10 Finland
Fracture of shaft of femur
47.8
15.2
18
*
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
47.8
15.2
18
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
4.7
15.1
37
87
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
33.8
15.0
19
6
M05BA02
ATC
clodronic acid; systemic
38.3
14.6
18
5
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
18.2
14.6
22
13
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
5.8
14.5
28
53
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
5.9
14.3
27
50
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.4
14.2
59
203
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
6.5
14.1
24
40
A06AD11
ATC
lactulose; oral
3.2
13.7
66
248
C50.4
ICD-10 Finland
Malignant neoplasm: Upper-outer quadrant of breast
36.0
13.7
17
5
WD205
NOMESCO Finland
Therapy of methastized malignancy with hormones
36.0
13.7
17
5
NEK99
NOMESCO Finland
Other operation on bone of pelvis
+∞
13.6
13
*
WZC30
NOMESCO Finland
Teaching
3.0
13.6
76
311
YNB10
NOMESCO Finland
Collection of stem cells for transplant
146.8
13.6
14
*
398
Kela drug reimbursment
Ixazomib
146.8
13.6
14
*
J01MA14
ATC
moxifloxacin; systemic
3.8
13.5
45
133
1501
Kela drug reimbursment
Palbociclib
27.3
13.5
18
7
R50.9
ICD-10 Finland
Fever, unspecified
3.1
13.4
68
263
L01BC06
ATC
capecitabine; oral
5.2
13.4
29
61
N03AX16
ATC
[U] pregabalin
2.8
13.4
90
407
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
16.1
13.3
21
14
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.6
13.1
108
540
A11CC03
ATC
alfacalcidol; systemic
10.1
12.8
25
27
A02BC02
ATC
pantoprazole; systemic
3.0
12.7
224
1600
NF3AD
NOMESCO Finland
Femur CT
73.3
12.7
14
*
159
Kela drug reimbursment
Pazopanib
73.3
12.7
14
*
S42.3
ICD-10 Finland
Fracture of shaft of humerus
18.4
12.7
19
11
M87.1
ICD-10 Finland
Osteonecrosis due to drugs
+∞
12.6
12
*
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
12.5
12.6
22
19
L01XE33
ATC
[U] palbociclib
135.8
12.5
13
*
AA1AA
NOMESCO Finland
Head X-ray examination
15.3
12.5
20
14
WX2DD
NOMESCO Finland
Low-dose CT of skeleton in whole body
39.5
12.3
15
*
WW200
NOMESCO Finland
Immunization
11.8
12.3
22
20
L02BA01
ATC
tamoxifen; oral
4.9
12.2
28
62
S72.2
ICD-10 Finland
Subtrochanteric fracture
28.1
12.2
16
6
8310/3-C64.9
ICD-O-3
Clear cell adenocarcinoma, NOS, of kidney, NOS
17.4
11.8
18
11
TK800
NOMESCO Finland
Hemodialysis
13.4
11.8
20
16
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
31.6
11.8
15
5
394
Kela drug reimbursment
Palbociclib
24.1
11.7
16
7
1502
Kela drug reimbursment
Cabozantinib
67.9
11.7
13
*
3012
Kela drug reimbursment
Cabozantinib
67.9
11.7
13
*
R4190
NOMESCO Finland
Nutritional therapy
5.4
11.7
24
48
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
14.5
11.6
19
14
YN1AD
NOMESCO Finland
CT examination of extremities for dose design of radiotherapy
+∞
11.5
11
*
WW402
NOMESCO Finland
Leucoferesis
124.9
11.5
12
*
1505
Kela drug reimbursment
Ixazomib
124.9
11.5
12
*
L02BG04
ATC
letrozole; oral
3.8
11.4
37
107
B01AB04
ATC
dalteparin; parenteral
4.9
10.9
25
55
L02BB04
ATC
enzalutamide; oral
29.3
10.8
14
5
163
Kela drug reimbursment
Abiraterone and enzalutamide
29.3
10.8
14
5
N18.0
ICD-10 Finland
End-stage renal disease
22.5
10.8
15
7
M49.5*C90.0
ICD-10 Finland
Vertebral fracture due to multiple myeloma
62.4
10.7
12
*
YN7AD
NOMESCO Finland
CT examination of spine for dose design of radiotherapy
62.4
10.7
12
*
C90.2
ICD-10 Finland
Extramedullary plasmacytoma
+∞
10.5
10
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.4
10.2
92
471
L02AE02
ATC
leuprorelin; implant, parenteral
4.9
10.2
23
50
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
3.6
10.0
35
107
L28
ICPC
Limited function/disability (L)
2.6
10.0
73
339
ZXE00
NOMESCO Finland
One hour or less
2.3
9.9
128
762
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.2
9.7
130
784
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.3
9.7
106
588
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
18.3
9.5
14
8
L01XE04
ATC
[U] sunitinib
103.4
9.5
10
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.5
9.4
72
340
NFU20
NOMESCO Finland
Removal of internal fixation device from femur
22.6
9.4
13
6
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
22.6
9.4
13
6
M907, C61,
ICD-10 Finland
+∞
9.4
9
*
L01XE26
ATC
[U] cabozantinib
+∞
9.4
9
*
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
10.0
9.4
18
19
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.8
9.4
30
86
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.6
9.2
62
275
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
16.3
9.1
14
9
AA1BD
NOMESCO Finland
Extensive CT of head and brain
8.4
9.0
19
24
Z94.0
ICD-10 Finland
Kidney transplant status
25.0
9.0
12
5
352
Kela drug reimbursment
Abiraterone and enzalutamide
25.0
9.0
12
5
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.4
8.9
23
56
HAC20
NOMESCO Finland
Total mastectomy
4.4
8.9
23
56
ZX070
NOMESCO Finland
Intensity modified radiotherapy
8.1
8.8
19
25
S42.2
ICD-10 Finland
Fracture of upper end of humerus
4.2
8.8
24
61
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.9
8.8
27
75
D70.89
ICD-10 Finland
Neutropenic splenomegaly
14.7
8.8
14
10
1XX32, ,
NOMESCO Finland
51.6
8.7
10
*
L01XE11
ATC
[U] pazopanib
51.6
8.7
10
*
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
8.7
8.7
18
22
NK6AN
NOMESCO Finland
Total body bone isotope imaging
7.3
8.7
20
29
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
12.1
8.7
15
13
N02AA01
ATC
morphine; systemic, rectal
12.1
8.7
15
13
ZXE20
NOMESCO Finland
More than three and less than five hours
2.6
8.6
55
238
ZXA00
NOMESCO Finland
Right side
2.2
8.6
93
510
L01AA03
ATC
melphalan; systemic
28.5
8.5
11
*
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
28.5
8.5
11
*
L02BX03
ATC
abiraterone; oral
28.5
8.5
11
*
V03AE01
ATC
polystyrene sulfonate; oral
20.8
8.5
12
6
L75
ICPC
Fracture: femur
20.8
8.5
12
6
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.3
8.5
34
113
L01CA04
ATC
vinorelbine; systemic
13.3
8.5
14
11
127
Kela drug reimbursment
Transplant complication
13.3
8.5
14
11
158
Kela drug reimbursment
Everolimus
92.7
8.5
9
*
WX320
NOMESCO Finland
Spinalanesthesy
2.2
8.4
90
491
NB6AD
NOMESCO Finland
Upper arm CT
+∞
8.4
8
*
L01XX50
ATC
[U] ixazomib
+∞
8.4
8
*
M90.0*A18.0
ICD-10 Finland
Bentuberculosis
+∞
8.4
8
*
WX200
NOMESCO Finland
Interscalenous plexus blockade
6.9
8.4
20
31
D64.9
ICD-10 Finland
Anaemia, unspecified
2.9
8.3
43
166
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
7.9
8.3
18
24
Z49.1
ICD-10 Finland
Extracorporeal dialysis
15.1
8.3
13
9
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
3.2
8.3
34
115
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
17.8
8.1
12
7
L04AD02
ATC
tacrolimus; systemic
22.8
8.1
11
5
X76
ICPC
Malignant neoplasm breast female
6.9
8.0
19
29
C10AA07
ATC
rosuvastatin; oral
0.3
8.0
33
779
N18.8
ICD-10 Finland
Other chronic renal failure
8.2
8.0
17
22
KAC10
NOMESCO Finland
Total nephrectomy with capsule
13.6
8.0
13
10
L04AA06
ATC
mycophenolic acid; systemic
9.8
7.9
15
16
E83.50
ICD-10 Finland
Hypercalcemia
9.8
7.9
15
16
NG4AA
NOMESCO Finland
Lower leg X-ray examination
4.6
7.8
19
44
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
15.6
7.8
12
8
S72.0
ICD-10 Finland
Fracture of neck of femur
4.2
7.8
21
53
L01AA01
ATC
cyclophosphamide; systemic
46.3
7.8
9
*
NFJ62
NOMESCO Finland
Internal fixation of fracture of other parts of femur with plate
46.3
7.8
9
*
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
6.5
7.7
19
31
ZXD10
NOMESCO Finland
Scheduled procedure
2.0
7.7
120
752
L01EF01
ATC
palbociclib; oral
19.0
7.7
11
6
N02BF02
ATC
pregabalin; oral
3.4
7.7
29
93
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
25.8
7.6
10
*
J05AB11
ATC
valaciclovir; oral
2.4
7.6
57
265
SPAT1254
SPAT
Administration of medicine
2.6
7.6
50
219
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
6.8
7.5
18
28
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.7
7.5
44
182
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
82.2
7.5
8
*
J05AB01
ATC
aciclovir; systemic
2.2
7.4
78
419
J01FF01
ATC
clindamycin; systemic
2.1
7.4
89
504
ZXA05
NOMESCO Finland
Left side
2.1
7.4
85
473
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.3
7.4
28
90
168
Kela drug reimbursment
Axitinib
+∞
7.3
7
*
343
Kela drug reimbursment
Pazopanib
+∞
7.3
7
*
M907, C5099,
ICD-10 Finland
+∞
7.3
7
*
M80.8
ICD-10 Finland
Other osteoporosis with pathological fracture
+∞
7.3
7
*
M907, C795,
ICD-10 Finland
+∞
7.3
7
*
5BA08, ,
NOMESCO Finland
30.9
7.2
9
*
L01EX07
ATC
cabozantinib; oral
30.9
7.2
9
*
WPA15
NOMESCO Finland
Palliative care consultation with the patient and loved ones
30.9
7.2
9
*
S72.4
ICD-10 Finland
Fracture of lower end of femur
30.9
7.2
9
*
V03AE02
ATC
sevelamer; oral
30.9
7.2
9
*
A12AA04
ATC
calcium carbonate; oral
9.1
7.1
14
16
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
4.4
7.1
18
43
C50.99
ICD-10 Finland
Breast, unspecified
4.4
7.1
18
43
SPAT1255
SPAT
Intravenous administration of medicine
3.3
7.1
27
87
Z3226
NOMESCO Finland
Physiotherapist
2.3
7.1
64
323
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.9
7.1
34
126
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
4.6
7.1
17
39
N17.9
ICD-10 Finland
Acute renal failure, unspecified
4.6
7.1
17
39
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
14.2
6.9
11
8
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
14.2
6.9
11
8
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
14.2
6.9
11
8
A41.9
ICD-10 Finland
Sepsis, unspecified
4.3
6.9
18
44
NBJ62
NOMESCO Finland
Internal fixation of fracture of shoulder or upper arm using plate and screws, humerus
8.6
6.9
14
17
NFJ54
NOMESCO Finland
Internal fixation of fracture of upper femur with intramedullary nail
11.3
6.9
12
11
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
9.7
6.9
13
14
KA1AE
NOMESCO Finland
Kidney ultrasound examination
7.5
6.8
15
21
NF3BA
NOMESCO Finland
Femur extensive X-ray examination
41.1
6.8
8
*
H3603, E103,
ICD-10 Finland
41.1
6.8
8
*
WW409
NOMESCO Finland
Other aferesis
23.2
6.7
9
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
3.2
6.7
27
90
N02BE01
ATC
paracetamol; systemic, rectal
3.2
6.7
259
2224
A10AC01
ATC
insulin (human); parenteral
2.8
6.7
35
136
WF003
NOMESCO Finland
Adjuvant radiotherapy
4.3
6.6
17
41
N02AX02
ATC
tramadol; systemic, rectal
1.9
6.6
135
915
HA1AA
NOMESCO Finland
X-ray mammography
2.8
6.6
34
131
WX306
NOMESCO Finland
Lumbar epidural anesthesy
3.7
6.6
21
60
Z3231
NOMESCO Finland
Registered nurse
2.0
6.6
89
524
116
Kela drug reimbursment
Prostate cancer
3.6
6.6
22
65
NK6AQ
NOMESCO Finland
Whole body bone SPET with low dose CT
71.4
6.5
7
*
M49.5*C79.5
ICD-10 Finland
Metastatic fracture of vertebra
71.4
6.5
7
*
322
Kela drug reimbursment
Sunitinib
71.4
6.5
7
*
Z49.0
ICD-10 Finland
Preparatory care for dialysis
14.7
6.4
10
7
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
3.5
6.4
22
66
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.4
6.4
46
209
GD1AD
NOMESCO Finland
Thorax CT examination
3.2
6.4
25
82
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
5.3
6.3
18
36
ZX108
NOMESCO Finland
Inhalation
18.5
6.3
9
5
WX882
NOMESCO Finland
High dependency care
7.3
6.3
14
20
M907, C5041,
ICD-10 Finland
+∞
6.3
6
*
N25.0
ICD-10 Finland
Renal osteodystrophy
27.3
6.3
8
*
N02AJ06
ATC
codeine and paracetamol; systemic
1.9
6.3
135
927
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
6.5
6.3
15
24
WX002
NOMESCO Finland
Sedation and analgesia
2.1
6.2
65
346
EBA10
NOMESCO Finland
Operative extraction of tooth
2.7
6.1
34
136
SPAT1229
SPAT
Assessment of need for aid
3.0
6.1
27
95
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
5.8
6.1
16
29
WD225
NOMESCO Finland
Demanding therapy of methastized malignancy with hormones
10.4
6.1
11
11
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
10.4
6.1
11
11

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
89
87
14.53
84.62
21.1
5.1
63.34
108.75
mg/l
0.28
79
73
89
87
14.53
84.62
21.0
5.1
41.36
30.21
mg/l
0.44
79
73
85
80
14.82
82.66
20.0
4.6
34.64
2.35
ratio
0.78
58
40
56
34
20.34
68.68
6.3
2.9
—
—
—
0
0
65
60
13.81
63.19
6.1
1.6
—
—
—
0
0
40
15
30.94
59.21
4.6
2.2
—
—
—
0
0
50
36
16.69
55.91
6.6
2.4
0.77
1.38
g/24h
0.58
37
22
48
43
13.27
47.04
1.8
1.9
—
—
—
0
0
102
229
6.43
46.61
1.6
1.4
—
—
—
0
0
115
325
5.31
39.89
17.6
6.0
1.10
1.06
mmol/l
0.75
110
300
176
702
5.06
39.54
8.8
4.1
—
—
—
0
0
188
804
5.07
38.22
21.8
4.1
7.39
7.40
ph
0.26
165
563
70
164
5.36
29.42
1.9
1.4
—
—
—
0
0
179
844
4.11
29.27
13.4
6.1
—
—
—
0
0
81
223
4.70
27.95
12.2
8.8
—
—
—
0
0
179
868
3.94
27.54
17.5
3.1
2.34
2.36
mmol/l
0.84
172
783
225
1288
4.80
26.95
31.6
7.0
1.21
1.21
mmol/l
0.43
198
1114
166
782
3.76
26.32
6.2
2.5
—
—
—
0
0
37
51
8.21
26.10
2.0
1.6
—
—
—
0
0
103
358
3.97
25.74
3.2
1.9
—
—
—
0
0
83
249
4.32
25.41
2.3
1.6
—
—
—
0
0
209
1165
4.13
25.25
14.9
6.4
0.60
0.69
%
1.54
202
1089
209
1166
4.13
25.19
14.9
6.5
9.14
8.92
%
0.44
202
1096
209
1166
4.13
25.19
14.5
6.3
2.44
2.83
%
2.04
202
1093
229
1383
4.60
24.08
43.7
10.6
3.86
4.14
e9/l
0.97
204
1205
33
45
8.18
23.42
1.9
1.6
149.58
134.59
au/ml
0.21
12
16
208
1190
3.91
23.36
14.5
6.4
22.75
27.36
%
7.20
203
1130
206
1180
3.82
22.89
14.2
6.3
60.48
57.54
%
2.46
200
1128
87
298
3.78
21.78
6.3
7.8
0.47
0.89
mmol/l
0.43
73
253
131
585
3.33
21.54
5.4
2.5
—
—
—
0
0
89
313
3.70
21.38
5.8
2.9
1.82
1.81
%
0.04
84
288
87
303
3.71
21.19
6.3
7.7
7.42
7.42
ph
0.27
41
160
72
220
4.06
21.17
10.2
2.7
9.01
10.49
g/l
1.01
67
201
86
304
3.64
20.40
6.4
7.6
5.12
5.12
kpa
0.00
81
291
99
387
3.41
20.01
4.9
2.4
20.11
22.63
%
1.23
93
361
208
1256
3.55
20.01
14.2
6.4
0.57
0.60
e9/l
0.65
180
1063
68
209
3.98
19.74
9.7
3.8
140.32
79.74
ng/l
1.68
56
178
208
1266
3.50
19.54
14.2
6.4
0.03
0.04
e9/l
5.96
180
1072
211
1300
3.53
19.32
15.2
6.7
0.15
0.19
e9/l
3.48
187
1123
84
302
3.54
19.30
2.5
1.6
—
—
—
0
0
209
1283
3.48
19.20
14.3
6.5
1.36
2.02
e9/l
7.89
188
1123
75
252
3.70
19.08
9.6
3.5
1.47
1.94
mmol/l
0.37
64
222
26
11
25.89
19.02
4.8
2.0
—
—
—
0
0
191
1120
3.22
18.81
6.3
2.7
—
—
estimate
—
0
0
146
738
3.04
18.75
5.8
3.2
0.34
0.42
e6/l
0.34
117
528
160
851
3.05
18.73
5.7
3.3
62.57
128.78
e6/l
0.33
129
642
115
510
3.13
18.61
9.8
2.6
2.51
2.46
mmol/l
2.74
110
460
25
32
8.48
18.58
1.6
1.3
—
—
—
0
0
75
257
3.62
18.48
10.0
3.6
7.36
7.39
ph
3.79
54
139
103
443
3.10
17.39
4.9
2.4
11.55
13.30
umol/l
1.80
97
411
98
412
3.12
17.18
5.0
2.4
2.09
2.32
g/l
3.82
92
380
141
736
2.84
16.50
3.5
2.9
—
—
—
0
0
132
667
2.85
16.41
9.0
2.8
343.98
351.39
umol/l
0.31
125
575
58
182
3.76
16.14
5.6
1.7
0.63
1.34
g/l
3.08
49
165
99
432
3.00
16.11
5.2
3.1
1.54
1.97
e6/l
0.31
64
210
167
965
2.81
15.86
6.8
4.0
74.50
82.99
e6/l
0.11
132
670
87
356
3.09
15.82
2.4
1.7
—
—
—
0
0
119
581
2.82
15.64
3.7
2.6
4.71
4.68
e6/l
0.01
112
527
51
151
3.91
15.39
10.9
3.7
23.57
24.35
mmol/l
0.75
51
151
108
507
2.84
15.22
4.4
2.8
515.90
520.93
mosm/kgh2o
0.10
99
435
101
463
2.85
14.83
5.2
2.9
1.04
1.05
e6/l
0.01
66
241
24
38
6.81
14.81
4.4
4.4
1.00
0.77
%
0.37
24
33
29
57
5.56
14.44
3.6
2.9
60.68
59.36
%
0.24
29
57
187
1188
2.73
14.05
12.7
12.6
1.15
1.23
inr
1.83
163
979
75
305
2.99
13.58
5.4
2.8
9.05
7.88
umol/l
0.16
61
271
25
24
11.32
13.55
3.7
3.4
786.24
924.37
mg
0.10
25
24
60
215
3.28
13.47
6.3
4.9
0.18
0.10
%
0.40
39
58
62
227
3.22
13.44
6.3
4.7
0.95
0.75
%
0.43
41
71
178
1126
2.59
13.12
30.8
11.6
0.00
0.00
e9/l
0.05
141
910
23
41
6.02
12.64
2.0
1.4
346.60
271.58
u/ml
0.22
15
19
63
241
3.08
12.63
5.3
2.8
65.41
70.50
e9/l
0.66
46
169
23
25
9.92
11.74
1.3
1.1
—
—
—
0
0
21
37
6.05
11.66
4.1
3.1
4.07
4.64
e9/l
0.53
21
37
32
84
4.17
11.28
4.4
3.2
501.73
276.24
mg/l
0.62
26
37
58
226
2.98
11.17
6.7
5.1
0.11
0.18
%
0.18
37
56
55
209
3.03
11.07
6.8
4.8
0.67
0.39
%
1.23
36
59
21
22
10.22
10.96
1.4
1.2
—
—
—
0
0
21
43
5.20
9.95
2.3
1.6
—
—
—
0
0
21
43
5.20
9.95
2.3
1.6
—
—
—
0
0
21
43
5.20
9.95
2.3
1.6
—
—
—
0
0
21
43
5.20
9.95
2.3
1.6
—
—
—
0
0
22
48
4.89
9.71
1.4
1.4
—
—
—
0
0
38
126
3.33
9.54
1.8
1.5
—
—
—
0
0
19
22
9.18
9.45
1.2
1.1
—
—
—
0
0
64
286
2.60
9.41
2.7
1.7
—
—
—
0
0
24
59
4.36
9.18
2.0
1.4
—
—
—
0
0
14
9
16.29
9.13
1.6
1.6
—
—
—
0
0
63
286
2.55
8.93
6.8
4.4
7.79
24.02
ug/l
0.56
53
236
16
16
10.53
8.64
1.7
1.8
29.14
32.94
%
0.32
16
16
211
1597
2.30
8.37
6.6
4.5
2577.38
133.87
e6/l
—
8
31
19
28
7.20
8.22
1.3
1.4
34.53
22.76
ng/l
0.72
19
28
121
746
2.10
8.20
27.2
6.4
—
—
—
0
0
19
44
4.56
7.81
1.3
1.3
—
—
—
0
0
35
126
3.03
7.65
1.3
1.2
—
—
—
0
0
14
14
10.46
7.62
3.1
6.3
14.59
17.28
%
1.34
14
14
10
5
20.66
7.18
1.6
1.4
—
—
—
0
0
19
48
4.17
7.01
4.9
2.7
—
—
—
0
0
54
255
2.38
6.94
4.9
2.5
36.58
34.27
u/l
0.15
45
213
23
68
3.60
6.86
5.2
2.9
57.94
64.08
%
0.64
23
68
17
40
4.46
6.85
1.1
1.1
—
—
—
0
0
63
1081
0.46
6.83
2.2
2.0
1.43
1.34
mmol/l
0.28
56
899
64
331
2.21
6.64
1.3
1.3
—
—
—
0
0
194
2300
0.49
6.58
7.7
6.9
40.41
39.74
mmol/mol
0.42
183
2154
152
1083
1.88
6.28
3.9
2.4
76.26
78.21
nmol/l
0.37
143
960
120
799
1.88
6.07
5.9
2.4
53.54
68.55
u/l
1.11
114
740
20
59
3.57
5.98
3.4
1.9
62.93
63.11
%
0.01
20
59
208
2392
0.49
5.83
5.3
6.4
2.70
2.70
mmol/l
0.02
188
2222
86
519
1.95
5.83
5.9
4.2
181.56
306.43
ng/l
0.52
71
425
91
560
1.93
5.82
2.9
2.0
1.95
1.27
mg/l
0.50
80
462
42
193
2.38
5.70
5.3
3.4
—
—
—
0
0
15
28
5.60
5.62
1.1
1.1
—
—
—
0
0
9
7
13.23
5.62
3.7
4.1
54.78
49.43
%
—
9
7
205
2363
0.51
5.60
5.0
5.6
4.60
4.64
mmol/l
0.22
185
2196
8
5
16.40
5.44
7.9
3.2
—
—
—
0
0
204
2351
0.51
5.44
4.9
5.5
1.37
1.48
mmol/l
3.55
184
2174
14
27
5.40
5.15
5.8
3.7
80.79
70.58
u/ml
0.06
14
27
150
1110
1.76
5.08
4.8
2.8
244.58
128.29
ug/l
4.79
143
1026
17
51
3.48
4.97
5.7
1.9
3.49
2.64
mmol/l
—
10
30
12
20
6.22
4.97
1.7
1.4
50395.00
83419.63
e6/l
—
6
8
20
67
3.14
4.94
7.9
3.2
0.90
1.40
index
—
10
42
12
21
5.92
4.81
1.8
1.6
—
—
—
0
0
18
58
3.25
4.73
1.2
1.2
—
—
—
0
0
95
627
1.78
4.71
2.4
2.2
3.33
2.97
mg/l
0.51
80
536
13
26
5.19
4.69
1.5
1.9
—
—
—
0
0
16
48
3.47
4.68
1.9
1.1
—
—
—
0
0
12
22
5.65
4.65
1.7
1.3
1086.14
3571.77
e6/l
—
7
13
84
540
1.79
4.53
11.6
5.2
—
—
—
0
0
15
37
4.22
4.48
1.5
1.4
1.53
1.52
mmol/l
0.02
15
37
11
20
5.68
4.33
1.8
1.4
—
—
—
0
0
14
34
4.28
4.27
3.0
2.7
33.64
32.41
pg
0.94
14
34
13
30
4.49
4.18
4.9
4.0
—
—
—
0
0
107
757
1.67
4.02
2.0
1.6
16.88
21.32
nmol/l
2.92
97
625
18
65
2.89
3.93
1.4
1.4
40014.11
15596.36
e6/l
—
9
47
11
23
4.93
3.91
1.3
1.4
—
—
—
0
0
68
428
1.78
3.88
2.3
1.7
1133.06
1195.65
nmol/l
0.20
53
319
10
19
5.42
3.86
1.0
1.1
155.00
108.21
pmol/l
—
10
19
133
1003
1.62
3.83
2.4
2.1
—
—
—
0
0
7
8
8.94
3.79
4.9
2.0
0.60
0.62
mmol/l
—
7
8
24
104
2.43
3.71
4.9
4.7
0.74
0.88
%
1.14
24
90
14
45
3.22
3.70
6.3
3.4
9.20
10.71
pmol/l
0.16
14
45
10
21
4.90
3.59
1.0
1.1
—
—
—
0
0
96
677
1.64
3.58
1.9
1.4
—
—
—
0
0
30
146
2.18
3.57
4.4
4.6
—
—
—
0
0
77
520
1.66
3.37
5.8
1.5
4.12
2.61
g/l
0.63
59
314
200
2253
0.61
3.34
4.6
4.7
1.44
1.28
mmol/l
2.50
180
2072
12
33
3.75
3.33
1.3
1.1
—
—
—
0
0
26
123
2.23
3.32
4.6
4.2
1.56
1.56
%
0.02
26
110
6
7
8.72
3.28
1.0
1.4
—
—
—
0
0
9
19
4.86
3.26
1.9
4.8
7.23
7.99
mmol/l
—
9
19
209
2326
0.60
3.24
5.4
5.4
6.00
6.03
mmol/l
0.09
189
2146
7
11
6.49
3.20
1.0
1.1
—
—
—
0
0
10
25
4.11
3.11
1.7
1.3
87.75
90.24
%
—
10
25
0
78
0.00
3.00
0.0
1.2
—
1.57
—
0
78
13
47
2.85
2.85
1.0
1.1
—
—
—
0
0
11
33
3.43
2.84
1.7
2.2
—
—
—
0
0
14
53
2.73
2.84
1.7
1.8
2.50
4.98
iu/l
—
5
25
15
59
2.63
2.83
1.2
1.5
313.00
223.32
miu/ml
—
5
27
0
75
0.00
2.80
0.0
1.1
—
0.66
—
0
13
105
794
1.52
2.77
2.3
2.1
131.82
299.29
u/l
1.09
100
745
126
990
1.50
2.77
6.0
3.8
26.01
34.45
ng/l
0.82
107
732
7
14
5.10
2.74
1.0
1.1
—
—
—
0
0
24
120
2.09
2.70
2.3
3.3
560.94
1445.94
u/ml
0.35
17
106
6
13
4.69
2.28
1.5
1.5
—
—
—
0
0
70
934
0.67
2.26
3.4
3.5
—
—
—
0
0
108
850
1.44
2.24
4.9
3.5
1825.90
1004.24
ng/l
0.84
97
732
17
81
2.17
2.17
1.6
1.3
133.60
308.65
ug/g
3.04
11
48
7
177
0.38
2.12
3.4
3.3
—
—
—
0
0
8
25
3.26
2.11
1.0
1.1
—
—
—
0
0
8
25
3.26
2.11
4.0
1.6
8.93
11.36
%
—
8
25
34
211
1.70
2.03
1.9
2.5
6.77
14.27
nmol/l
4.63
29
198
5
11
4.61
1.95
1.2
1.1
—
—
—
0
0
134
1117
1.38
1.93
2.6
2.1
92.40
97.92
pmol/l
0.64
86
551
7
22
3.24
1.89
1.4
1.7
—
—
—
0
0
33
209
1.66
1.84
4.0
2.3
0.43
0.24
e6/l
0.25
33
198
16
81
2.03
1.78
1.3
1.3
—
—
—
0
0
25
149
1.74
1.73
4.3
2.4
0.62
0.61
%
0.10
25
149
25
150
1.73
1.70
4.3
2.5
0.95
1.24
%
1.55
25
150
45
314
1.52
1.69
1.8
1.4
—
—
—
0
0
155
1342
1.35
1.68
5.0
3.8
0.00
0.00
estimate
-0.00
47
251
90
720
1.37
1.62
5.1
3.1
0.00
0.02
estimate
0.99
44
218
153
1331
1.33
1.56
5.1
3.7
0.00
5.80
estimate
0.50
52
280
5
15
3.37
1.53
1.6
3.5
3003.60
909.40
u/ml
—
5
15
6
21
2.90
1.51
1.5
1.0
—
—
—
0
0
10
200
0.48
1.49
1.2
1.5
—
—
—
0
0
22
133
1.71
1.47
6.6
6.2
—
—
—
0
0
151
1319
1.31
1.46
5.1
3.7
0.00
0.00
estimate
-0.00
49
274
5
16
3.16
1.44
1.6
1.1
—
—
—
0
0
10
47
2.17
1.35
6.8
6.0
102.60
104.84
mmol/l
—
10
38
10
47
2.17
1.35
6.8
6.0
10.90
11.26
mmol/l
—
10
38
43
312
1.45
1.35
6.1
3.4
4.22
5.28
e9/l
0.61
37
276
17
99
1.76
1.30
1.3
1.3
—
—
—
0
0
120
1033
1.28
1.24
4.6
3.5
6.16
6.15
ph
0.05
66
572
5
19
2.66
1.22
1.2
1.4
—
—
—
0
0
8
41
1.98
1.09
1.0
1.1
—
3.57
—
0
10
21
138
1.56
1.06
1.1
1.2
186.11
128.18
u/ml
—
9
54
12
67
1.83
1.06
6.5
5.7
1.02
1.26
mmol/l
1.16
12
54
5
22
2.29
1.04
1.0
1.1
—
—
—
0
0
30
216
1.44
1.00
2.1
2.3
4.33
7.69
ug/l
1.33
21
196
6
28
2.17
0.92
1.0
1.1
—
—
—
0
0
8
44
1.84
0.86
1.4
1.2
—
—
—
0
0
210
2212
0.80
0.86
7.7
5.3
2.02
1.94
mu/l
0.35
199
2015
45
554
0.78
0.81
4.1
3.7
1.02
1.02
kg/l
0.33
38
370
84
725
1.23
0.81
4.5
3.6
0.00
0.00
estimate
-0.00
46
250
12
74
1.65
0.79
1.5
1.1
—
—
—
0
0
0
27
0.00
0.78
0.0
1.2
—
—
—
0
0
150
1625
0.83
0.77
4.3
3.4
66.71
49.22
u/l
1.59
140
1519
41
508
0.77
0.77
3.0
3.3
1.13
0.84
ug/l
0.69
31
332
247
2542
0.76
0.71
83.9
24.7
3.98
4.49
e12/l
32.41
241
2479
247
2542
0.76
0.71
83.9
24.7
6.45
6.69
e9/l
0.85
240
2478
7
41
1.73
0.70
2.1
2.3
—
—
—
0
0
44
365
1.24
0.61
1.3
1.2
—
—
—
0
0
242
2340
1.25
0.60
65.7
15.9
27.41
24.33
mg/l
0.84
235
1939
42
351
1.23
0.56
1.2
1.3
213.33
516.67
titre
—
6
84
14
99
1.44
0.55
1.8
3.1
—
—
—
0
0
6
97
0.61
0.53
1.0
1.7
—
—
—
0
0
26
316
0.80
0.44
1.3
1.3
—
—
—
0
0
5
31
1.62
0.43
1.2
1.6
272.20
275.45
mosm/kgh2o
—
5
20
5
32
1.57
0.42
1.2
1.1
—
—
—
0
0
38
441
0.84
0.42
1.3
1.3
7.09
11.22
u/ml
—
9
151
0
15
0.00
0.41
0.0
1.2
—
0.46
—
0
7
0
19
0.00
0.39
0.0
2.8
—
—
—
0
0
5
37
1.36
0.37
1.2
1.1
—
—
—
0
0
5
37
1.36
0.37
1.2
1.1
—
—
—
0
0
5
37
1.36
0.37
4.2
2.7
107.20
106.24
mmol/l
—
5
37
5
37
1.36
0.37
4.2
2.7
4.04
3.96
mmol/l
—
5
37
5
37
1.36
0.37
4.2
2.7
1.16
1.19
mmol/l
—
5
37
105
981
1.11
0.35
5.0
3.5
0.00
0.02
estimate
0.78
43
226
6
45
1.34
0.34
1.0
1.1
—
—
—
0
0
86
925
0.90
0.33
5.9
4.1
46.30
7.73
mg/mmol
1.33
63
555
21
174
1.22
0.32
2.4
2.6
—
8.41
—
0
12
34
298
1.16
0.30
2.2
2.5
141.25
116.65
ug/g
0.17
28
244
10
77
1.31
0.26
1.3
1.1
—
—
—
0
0
15
123
1.23
0.26
1.1
1.3
—
—
—
0
0
19
223
0.84
0.25
1.6
2.3
6.43
6.01
ph
1.00
14
147
12
148
0.80
0.25
1.3
1.2
61.83
145.96
u/ml
1.51
12
139
6
83
0.72
0.24
1.3
1.2
—
106.25
—
0
8
17
200
0.84
0.23
1.5
1.5
—
—
—
0
0
44
480
0.90
0.22
1.3
1.3
33.33
32.88
iu/ml
—
9
143
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
4.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
4.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
3.5
—
33.42
—
0
8
22
248
0.88
0.19
1.5
1.6
—
—
—
0
0
182
1861
0.94
0.17
7.2
4.2
14.84
14.78
pmol/l
0.11
174
1686
5
70
0.71
0.17
2.0
1.9
202.40
245.00
pmol/l
—
5
63
15
172
0.86
0.16
1.3
1.3
—
—
—
0
0
6
80
0.74
0.15
1.0
1.2
—
3.22
—
0
12
14
122
1.16
0.14
1.0
1.1
—
—
—
0
0
14
122
1.16
0.14
1.4
1.8
—
—
—
0
0
91
944
0.95
0.14
4.7
3.3
6.72
7.35
mmol/l
0.74
79
787
5
44
1.14
0.10
3.0
3.1
1.14
0.78
nmol/l
—
5
37
243
2410
1.06
0.09
42.2
14.1
—
—
—
0
0
8
77
1.04
0.07
1.5
2.6
13.51
11.99
mg/l
—
8
72
93
909
1.03
0.07
4.7
3.4
154.80
43.30
mg/l
1.39
71
572
81
830
0.97
0.07
7.2
5.4
5.35
2.52
ug/l
0.92
70
751
14
128
1.10
0.07
2.4
2.5
—
—
—
0
0
10
90
1.12
0.05
1.1
1.2
—
3.06
—
0
9
245
2437
1.04
0.05
65.3
19.3
4.01
3.98
mmol/l
0.65
240
2385
18
188
0.95
0.02
1.2
1.2
—
—
—
0
0
12
116
1.04
0.00
8.9
4.5
36.82
36.95
°c
0.65
12
116
25
246
1.02
0.00
1.4
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
3.56
—
0
5
0
5
0.00
0.00
0.0
1.0
—
0.02
—
0
5
0
5
0.00
0.00
0.0
2.6
—
107.60
—
0
5
0
5
0.00
0.00
0.0
1.4
—
1.99
—
0
5
0
5
0.00
0.00
0.0
2.2
—
10.78
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
53.33
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
7
69
1.01
-0.00
7.9
4.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
56
560
1.00
-0.00
1.4
1.3
1.47
1.30
u/ml
—
7
143
0
7
0.00
-0.00
0.0
1.4
—
8.78
—
0
7
0
7
0.00
-0.00
0.0
10.0
—
7.77
—
0
7
0
6
0.00
-0.00
0.0
1.3
—
59.17
—
0
6
0
9
0.00
-0.00
0.0
1.1
—
222.67
—
0
9
0
7
0.00
-0.00
0.0
4.7
—
6.64
—
0
7
12
120
1.00
-0.00
1.1
1.1
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint M13_OSTEOPATHYINOTH and mortality.

Females

Parameter HR [95% CI] p-value
M13_OSTEOPATHYINOTH 9.092 [6.48, 12.75] < 0.001
Birth year 0.993 [0.98, 1.0] 0.114

During the follow-up period (1.1.1998 — 31.12.2019), 430 out of 733 females with M13_OSTEOPATHYINOTH died.

Males

Parameter HR [95% CI] p-value
M13_OSTEOPATHYINOTH 7.116 [4.53, 11.17] < 0.001
Birth year 0.985 [0.98, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 356 out of 636 males with M13_OSTEOPATHYINOTH died.

Mortality risk

Mortality risk for people of age

years, who have M13_OSTEOPATHYINOTH.

N-year risk Females Males
1 0.763% 1.031%
5 4.847% 6.694%
10 12.775% 16.411%
15 22.181% 29.36%
20 35.371% 45.528%

Relationships between endpoints

↥

Index endpoint: M13_OSTEOPATHYINOTH – Osteopathy in diseases classified elsewhere

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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