protein energy malnutrition: A nutritional deficit that is caused by inadequate protein or calorie intake.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
247 |
4. Check minimum number of eventsNone |
247 |
5. Include endpointsNone |
247 |
6. Filter based on genotype QC (FinnGen only) |
214 |
Control definitions (FinnGen only)
- Control exclude
- E4_MALNUTRITION
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- E40-E46
- Name in latin
- Malnutritio non specificata ex deficientia proteino-energetica
Unspecified protein-energy malnutrition
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2837 | 1661 | 1166 |
| Only index persons | 2520 | 1510 | 1010 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.05 | 0.03 |
| Only index persons | 0.05 | 0.06 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 75.04 | 77.51 | 71.59 |
| Only index persons | 75.85 | 78.14 | 72.43 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 214 | 117 | 97 |
| Unadjusted period prevalence (%) | 0.04 | 0.04 | 0.04 |
| Median age at first event (years) | 72.67 | 69.39 | 76.62 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 226
- Matched controls
- 2260
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E46
ICD-10 Finland
Unspecified protein-energy malnutrition
+∞
310.1
220
*
E86
ICD-10 Finland
Volume depletion
16.6
43.6
39
28
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
8.8
21.8
29
37
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.9
21.1
92
341
E87.6
ICD-10 Finland
Hypokalaemia
7.8
19.1
28
40
A28
ICPC
Limited function/disability NOS
3.6
18.3
89
349
R63.4
ICD-10 Finland
Abnormal weight loss
6.9
17.7
29
47
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
4.7
16.3
42
104
JN3AD
NOMESCO Finland
Abdominal CT examination
4.2
16.3
51
147
SPAT1229
SPAT
Assessment of need for aid
5.0
16.2
39
91
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
7.9
16.0
23
32
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.1
15.3
101
467
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.1
15.2
104
491
D64.9
ICD-10 Finland
Anaemia, unspecified
3.8
14.8
55
178
AA1AD
NOMESCO Finland
CT of head and brain
2.9
13.5
100
486
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
6.3
13.5
24
42
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.8
13.2
111
576
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
4.9
13.1
31
71
SPAT1222
SPAT
Counselling/guidance promoting independent living
3.1
12.5
65
258
L28
ICPC
Limited function/disability (L)
2.9
11.9
77
345
I95.1
ICD-10 Finland
Orthostatic hypotension
4.9
11.5
27
61
N17.9
ICD-10 Finland
Acute renal failure, unspecified
5.2
11.5
25
53
Z25.1
ICD-10 Finland
Need for immunization against influenza
5.1
11.0
24
51
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.4
10.9
29
73
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.2
10.5
47
169
R53
ICD-10 Finland
Malaise and fatigue
2.5
10.1
89
459
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
4.0
10.1
31
87
ZXD05
NOMESCO Finland
Urgent procedure
2.5
9.9
84
426
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.8
9.5
60
261
R4190
NOMESCO Finland
Nutritional therapy
5.1
9.3
20
42
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.1
9.2
45
170
JN4AD
NOMESCO Finland
Body CT examination
3.2
8.9
40
144
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.2
8.8
38
133
R4110
NOMESCO Finland
Physiotherapy
2.4
8.8
85
452
C03CA01
ATC
furosemide; systemic
2.3
8.8
110
655
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
4.1
8.8
25
66
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.7
8.6
55
240
B03BA03
ATC
hydroxocobalamin; parenteral
3.8
8.5
27
77
SPAT1254
SPAT
Administration of medicine
2.7
8.3
53
231
JDB10
NOMESCO Finland
Percutaneous gastrostomy
15.2
8.3
13
9
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.3
8.3
33
110
SPAT1301
SPAT
No procedures
2.3
8.2
90
505
S97
ICPC
Chronic ulcer skin
3.5
8.0
30
96
EBA15
NOMESCO Finland
Extraction of multiple teeth
6.6
7.7
19
31
OAB73
NOMESCO Finland
Prevention and treatment of malnutrition
19.2
7.7
11
6
WX302
NOMESCO Finland
Thoracal epidural anesthesy
4.5
7.6
19
45
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.3
7.6
31
105
S72.1
ICD-10 Finland
Pertrochanteric fracture
4.7
7.6
18
41
N05AX08
ATC
risperidone; systemic
2.8
7.3
40
160
JN4CD
NOMESCO Finland
Very extensive body CT
4.8
7.3
17
38
SPAT1216
SPAT
Assessment of functional ability
2.4
6.9
55
265
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
4.5
6.9
17
40
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.4
6.8
53
253
W19
ICD-10 Finland
Unspecified fall
2.8
6.8
37
148
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.3
6.8
59
296
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
5.8
6.8
18
33
SPAT1255
SPAT
Intravenous administration of medicine
3.6
6.8
23
69
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
9.1
6.6
13
15
A46
ICD-10 Finland
Erysipelas
2.5
6.6
46
208
Z51.5
ICD-10 Finland
Palliative care
2.8
6.5
34
133
Z2446
NOMESCO Finland
Social worker
3.2
6.5
26
87
N02AA05
ATC
oxycodone; systemic
2.3
6.5
63
331
L89
ICD-10 Finland
Decubitus ulcer and pressure area
6.9
6.5
15
23
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.4
6.4
50
238
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.1
6.4
18
47
K59.09
ICD-10 Finland
Constipation, unspecified
3.1
6.3
28
100
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
6.2
122
832
I50.9
ICD-10 Finland
Heart failure, unspecified
2.2
6.2
60
314
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.3
6.1
24
79
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
4.1
6.1
17
44
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.9
6.0
29
108
TPX10
NOMESCO Finland
Implantation of vascular injection port
5.3
6.0
17
34
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
113
339
5.67
37.44
8.0
4.4
0.76
0.81
mmol/l
3.93
108
320
179
873
6.05
30.90
9.9
5.2
29.79
35.11
g/l
16.94
173
815
129
553
4.11
24.60
3.4
2.5
3.40
2.89
mg/l
0.78
118
473
130
599
3.76
21.48
3.9
2.6
57.03
63.52
u/l
0.36
124
558
176
1019
4.29
20.00
15.5
7.9
1.20
1.21
mmol/l
1.99
150
882
166
927
3.98
19.84
12.2
7.5
1.20
1.22
mmol/l
2.34
156
845
95
373
3.67
19.74
2.5
1.8
1284.09
1159.71
nmol/l
0.65
73
276
57
162
4.37
18.67
2.4
1.6
—
—
—
0
0
152
841
3.47
17.56
3.9
2.8
73.68
78.87
nmol/l
1.18
145
749
133
697
3.21
16.50
5.2
3.2
2.29
2.36
mmol/l
3.63
125
629
149
858
3.16
15.24
3.1
2.2
83.45
97.21
pmol/l
2.52
98
420
28
52
6.00
14.89
1.5
1.6
—
—
—
0
0
47
138
4.04
14.52
4.6
5.6
2.70
1.83
mmol/l
0.75
33
101
128
693
2.95
14.35
5.5
3.7
371.61
136.24
e6/l
0.33
109
535
65
241
3.38
14.17
3.1
4.4
246.37
246.94
u/l
0.01
60
229
25
46
5.99
13.39
1.3
1.4
225.29
312.39
ug/g
1.09
14
31
143
847
2.87
13.14
4.6
3.1
221.06
121.08
ug/l
2.22
135
772
129
736
2.75
12.55
6.2
3.7
—
—
—
0
0
111
591
2.73
12.33
2.5
1.8
20.27
21.74
nmol/l
0.37
100
494
108
569
2.72
12.23
5.7
4.7
0.00
0.01
estimate
0.50
37
194
31
76
4.57
12.03
1.4
1.2
—
—
—
0
0
51
180
3.37
11.87
6.3
4.0
—
—
—
0
0
59
233
3.07
11.36
6.2
5.0
1.90
1.95
mmol/l
0.03
52
188
129
766
2.59
11.13
6.9
4.5
42.20
45.82
ng/l
0.13
119
564
38
119
3.64
10.57
2.0
1.4
—
—
—
0
0
115
659
2.52
10.53
4.8
3.7
2574.41
1666.05
ng/l
1.11
106
552
108
611
2.47
10.05
3.8
2.2
209.92
252.76
u/l
0.27
103
581
99
541
2.48
9.90
6.0
3.9
0.09
0.01
estimate
0.40
35
163
70
329
2.63
9.57
6.3
3.6
5.66
2.70
e6/l
1.27
53
160
83
427
2.49
9.37
2.0
1.9
441.16
471.16
pmol/l
0.36
61
351
65
298
2.66
9.31
14.1
7.7
102.49
104.22
mmol/l
1.53
65
298
149
1000
2.44
9.15
6.3
4.6
0.00
0.00
estimate
-0.00
44
211
47
183
2.98
9.14
5.7
2.8
0.22
0.95
e6/l
0.77
47
175
45
174
2.98
8.85
5.4
3.8
99.19
71.36
ng/l
0.84
39
152
155
1072
2.42
8.69
19.8
10.7
4.59
4.15
e9/l
1.47
145
926
148
1006
2.37
8.59
6.1
4.6
0.00
7.45
estimate
0.50
44
218
148
1013
2.34
8.35
6.3
4.6
0.07
0.00
estimate
0.49
43
200
81
432
2.36
8.28
3.9
3.0
2.49
2.46
mmol/l
0.58
74
377
18
26
7.42
7.95
1.2
1.2
8487.46
1403.35
e6/l
0.42
13
20
118
753
2.19
7.68
6.6
4.6
0.00
0.03
estimate
0.96
33
178
177
1335
2.50
7.62
6.0
4.6
17.49
13.03
mm/h
2.63
170
1214
126
834
2.15
7.37
4.2
3.0
—
—
estimate
—
0
0
25
75
3.62
7.35
2.3
2.5
—
—
—
0
0
21
56
4.03
7.26
1.5
1.9
—
—
—
0
0
21
57
3.96
7.09
1.3
3.4
1.32
4.38
ratio
1.15
13
32
40
165
2.73
6.92
2.0
1.7
2.30
1.48
%
2.85
31
141
96
592
2.08
6.56
4.7
3.5
1.03
0.43
e6/l
0.97
78
440
21
62
3.63
6.31
1.4
3.5
52.82
70.23
mg/l
0.28
16
53
21
62
3.63
6.31
1.4
3.6
54.65
62.52
mg/l
0.08
16
53
15
24
6.61
6.28
2.3
2.3
31.53
32.08
pg
0.11
15
24
65
354
2.17
6.07
2.6
2.1
—
—
—
0
0
51
251
2.33
6.07
11.6
9.0
1.31
1.19
mmol/l
0.06
39
200
15
41
3.85
5.01
1.5
1.7
—
—
—
0
0
146
1112
1.88
4.86
5.2
3.3
65.82
47.30
u/l
1.02
139
1037
11
17
6.74
4.83
1.1
1.2
—
—
—
0
0
21
76
2.94
4.59
1.5
1.7
6.72
5.36
iu/ml
—
9
16
50
272
2.08
4.58
2.6
1.9
—
—
—
0
0
48
258
2.09
4.53
2.8
2.0
—
—
—
0
0
11
20
5.72
4.34
1.7
1.5
11.55
13.60
u/l
0.65
11
20
71
444
1.87
4.34
5.4
4.9
1.02
1.02
kg/l
1.30
61
312
18
62
3.07
4.28
1.3
1.4
0.22
0.22
g/l
0.02
18
62
72
455
1.85
4.25
1.6
1.3
0.76
1.12
u/ml
0.84
28
122
18
63
3.02
4.17
1.3
1.4
1.25
1.16
g/l
0.54
18
63
12
26
4.81
4.12
1.3
1.2
15418.67
36314.75
e6/l
—
6
16
200
1737
2.32
4.08
47.5
18.6
31.40
25.32
mg/l
1.94
187
1456
164
1331
1.85
4.07
5.5
4.3
15.29
15.05
pmol/l
0.50
155
1185
21
82
2.72
4.01
8.3
8.3
1.49
1.43
mg/l
0.21
21
70
7
8
8.98
3.80
3.0
1.8
97.57
243.25
nmol/l
—
7
8
12
30
4.16
3.65
1.0
1.2
—
—
—
0
0
15
51
3.08
3.65
1.9
1.3
—
—
—
0
0
67
436
1.76
3.51
4.6
2.6
—
—
—
0
0
14
47
3.11
3.48
1.3
1.6
—
—
—
0
0
184
1588
1.85
3.26
6.7
5.4
2.04
1.96
mu/l
0.31
175
1426
12
34
3.67
3.25
1.3
1.4
—
—
—
0
0
12
34
3.67
3.25
1.4
1.3
—
—
—
0
0
9
20
4.64
3.14
4.8
2.5
—
—
—
0
0
25
120
2.22
3.12
2.6
1.9
—
—
—
0
0
61
401
1.71
3.04
5.6
3.9
66.62
307.19
ng/l
1.89
47
329
17
69
2.58
3.04
1.5
1.6
—
—
—
0
0
184
1611
1.76
2.81
41.8
18.3
77.51
76.48
ml/min/173m2
0.22
176
1494
12
40
3.11
2.74
2.0
1.5
—
—
—
0
0
33
188
1.88
2.63
3.8
2.1
42.00
29.50
u/l
0.91
33
151
16
68
2.46
2.62
1.4
1.7
—
—
—
0
0
7
15
4.78
2.61
2.6
1.8
4.14
4.23
nmol/l
—
7
15
8
20
4.11
2.59
1.1
1.1
—
—
—
0
0
9
26
3.56
2.51
1.0
1.8
—
—
—
0
0
169
1467
1.60
2.44
53.6
23.3
14.80
13.79
%
8.85
169
1454
14
58
2.51
2.42
1.9
1.4
—
—
—
0
0
9
27
3.43
2.42
1.7
1.3
—
—
—
0
0
5
8
6.36
2.38
1.2
1.1
—
—
—
0
0
180
1591
1.65
2.36
6.1
6.6
38.55
39.93
mmol/mol
1.06
168
1465
9
28
3.30
2.33
1.0
1.8
—
—
—
0
0
64
456
1.56
2.27
3.1
3.1
325.59
347.73
umol/l
0.65
59
384
15
67
2.33
2.23
2.4
2.0
—
—
—
0
0
6
14
4.37
2.16
4.3
2.4
—
—
—
0
0
7
20
3.58
2.07
1.0
1.3
—
—
—
0
0
24
134
1.89
2.05
20.5
8.4
24.17
24.38
mmol/l
0.10
24
128
15
71
2.19
1.97
2.5
2.2
—
—
—
0
0
5
11
4.62
1.95
1.2
1.5
—
—
—
0
0
5
11
4.62
1.95
1.2
1.5
—
—
—
0
0
11
46
2.46
1.88
1.0
1.3
—
—
—
0
0
13
60
2.24
1.81
2.1
1.5
—
—
—
0
0
11
47
2.41
1.80
1.4
1.6
—
—
—
0
0
12
54
2.29
1.77
1.5
1.7
—
—
—
0
0
8
30
2.73
1.74
1.3
1.7
—
—
—
0
0
7
24
2.98
1.73
1.6
1.7
—
—
—
0
0
7
24
2.98
1.73
1.6
1.7
—
—
—
0
0
7
24
2.98
1.73
1.6
1.7
—
—
—
0
0
5
14
3.63
1.62
1.2
1.5
—
—
—
0
0
5
14
3.63
1.62
1.2
1.5
—
—
—
0
0
171
1544
1.44
1.56
4.1
4.3
1.21
1.26
mmol/l
0.45
157
1389
23
140
1.72
1.52
2.6
3.2
45.37
62.47
ml/min/173m2
—
9
55
6
21
2.91
1.51
2.2
1.5
—
—
—
0
0
10
45
2.28
1.48
1.8
1.4
—
—
—
0
0
9
38
2.42
1.47
1.4
1.8
—
—
—
0
0
57
440
1.40
1.32
2.8
1.7
1.51
1.44
mg/l
0.09
49
355
6
24
2.54
1.31
1.7
1.7
—
—
—
0
0
6
24
2.54
1.31
1.7
1.7
—
—
—
0
0
8
36
2.27
1.25
1.3
1.3
0.77
0.88
nmol/l
—
8
29
54
683
0.72
1.25
2.1
2.0
1.33
1.29
mmol/l
0.15
44
563
6
25
2.44
1.25
1.7
1.6
—
—
—
0
0
9
45
2.04
1.25
1.4
1.8
—
—
—
0
0
64
510
1.36
1.21
4.1
5.4
2.29
3.10
ug/l
0.43
57
431
5
20
2.53
1.15
1.2
1.2
—
—
—
0
0
11
58
1.94
1.14
1.5
1.2
—
—
—
0
0
13
216
0.58
1.11
1.7
1.5
—
—
—
0
0
18
115
1.61
1.03
2.3
2.5
—
18.27
—
0
9
10
53
1.93
1.03
1.1
1.3
—
—
—
0
0
5
23
2.20
0.98
1.0
2.0
—
—
—
0
0
5
23
2.20
0.98
1.0
2.0
—
—
—
0
0
5
23
2.20
0.98
1.0
2.0
—
—
—
0
0
176
1643
1.32
0.96
4.8
5.2
5.77
5.99
mmol/l
1.29
159
1475
8
42
1.94
0.89
1.4
1.2
—
—
—
0
0
8
47
1.73
0.81
1.9
1.4
—
—
—
0
0
8
47
1.73
0.81
1.9
1.4
—
—
—
0
0
22
297
0.71
0.76
2.1
1.7
—
—
—
0
0
43
347
1.30
0.75
5.3
3.3
1.00
1.23
e6/l
0.23
25
179
8
51
1.59
0.61
1.0
1.4
—
2.61
—
0
12
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
14
97
1.47
0.60
1.2
1.4
—
35.83
—
0
10
16
218
0.71
0.59
4.2
4.9
42.30
32.39
%
—
10
133
0
22
0.00
0.59
0.0
1.4
—
—
—
0
0
171
1627
1.21
0.57
4.6
5.1
4.26
4.53
mmol/l
2.65
156
1486
6
37
1.64
0.56
8.2
2.8
5.32
9.15
pmol/l
—
6
37
26
209
1.28
0.49
13.8
9.4
—
—
—
0
0
7
46
1.54
0.48
1.0
1.2
—
—
—
0
0
25
305
0.80
0.45
2.5
3.2
1.89
0.87
ug/l
0.64
19
196
8
58
1.39
0.42
1.5
1.2
—
—
—
0
0
168
1619
1.15
0.36
4.5
5.0
1.44
1.48
mmol/l
0.39
155
1469
6
44
1.37
0.34
1.0
1.3
—
46.95
—
0
6
6
47
1.28
0.32
1.2
1.9
0.73
6.82
mg/l
—
6
31
35
307
1.17
0.31
1.3
1.3
15.62
31.33
iu/ml
1.70
13
100
12
152
0.78
0.30
1.6
2.4
—
—
—
0
0
7
56
1.26
0.29
1.1
1.1
—
5.53
—
0
6
107
1016
1.10
0.27
3.1
2.9
—
—
—
0
0
57
613
0.91
0.23
4.7
3.9
18.35
8.67
mg/mmol
0.59
42
379
5
39
1.29
0.23
1.4
1.4
—
—
—
0
0
31
277
1.14
0.22
1.4
1.3
1.29
11.67
u/ml
2.56
11
105
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
10.85
—
0
13
37
403
0.90
0.19
4.0
4.4
22.17
22.54
%
0.04
19
194
7
59
1.19
0.18
1.6
1.2
—
—
—
0
0
7
59
1.19
0.18
1.9
1.7
—
—
—
0
0
170
1668
1.08
0.15
4.9
5.9
2.38
2.62
mmol/l
2.60
157
1520
12
137
0.87
0.12
1.4
2.2
—
—
—
0
0
5
60
0.83
0.08
2.4
2.2
—
—
—
0
0
10
88
1.14
0.08
1.5
1.4
—
—
—
0
0
15
149
1.01
0.00
1.7
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
0.34
—
0
6
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
71
0.99
-0.00
2.0
2.1
—
—
—
0
0
9
95
0.95
-0.00
1.2
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
0.23
—
0
5
0
8
0.00
-0.00
0.0
1.4
—
7.60
—
0
8
0
7
0.00
-0.00
0.0
1.0
—
41.91
—
0
7
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint E4_PROTMALNAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_PROTMALNAS | 2.983 [1.98, 4.5] | < 0.001 |
| Birth year | 0.999 [0.99, 1.01] | 0.849 |
During the follow-up period (1.1.1998 — 31.12.2019), 423 out of 1180 females with E4_PROTMALNAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_PROTMALNAS | 4.251 [2.36, 7.66] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.108 |
During the follow-up period (1.1.1998 — 31.12.2019), 339 out of 773 males with E4_PROTMALNAS died.
Mortality risk
Mortality risk for people of age
years, who have E4_PROTMALNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.239% | 1.022% |
| 5 | 1.836% | 5.449% |
| 10 | 5.126% | 13.589% |
| 15 | 9.269% | 24.479% |
| 20 | 16.303% | 39.043% |
Relationships between endpoints
↥Index endpoint: E4_PROTMALNAS – Unspecified protein-energy malnutrition
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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