Benign neoplasm: Brain, supratentorial

CD2_BENIGN_BRAIN_SUPRATENT

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D33.0
  • Cause of death: ICD-10 D33.0

2 out of 7 registries used, show all original rules.

666

4. Check minimum number of events

None

666

5. Include endpoints

None

666

6. Filter based on genotype QC (FinnGen only)

594

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D33
Name in latin
Neoplasma benignum cerebri supratentoriale

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4145 2224 1899
Only index persons 3782 2059 1723
Unadjusted period prevalence (%)
Whole population 0.06 0.06 0.05
Only index persons 0.07 0.08 0.07
Median age at first event (years)
Whole population 49.48 51.35 47.25
Only index persons 48.74 50.53 46.61

-FinnGen-

Key figures

All Female Male
Number of individuals 594 344 250
Unadjusted period prevalence (%) 0.12 0.12 0.11
Median age at first event (years) 50.59 47.10 55.38

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
612
Matched controls
6120
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
22.3
307.7
329
303
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
143.6
307.7
238
27
D33.00
ICD-10 Finland
Medial pilosytic astrocytoma of the cerebrum
+∞
218.2
196
*
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
79.5
206.1
111
17
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
14.4
159.7
163
150
D33.07
ICD-10 Finland
Colloid coast in cerebral ventricle
+∞
158.4
145
*
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
50.7
155.4
91
21
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
19.8
143.5
118
73
D33.02
ICD-10 Finland
Another benign medial tumor of the cerebrum
+∞
112.0
104
*
N03AF02
ATC
oxcarbazepine; oral
14.4
111.9
109
91
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
7.6
105.3
184
329
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
21.3
103.0
80
43
N03AX14
ATC
levetiracetam; systemic
15.1
97.6
91
70
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
16.6
91.2
80
55
9530/0-C70.0
ICD-O-3
Meningioma, NOS, of cerebral meninges
42.2
88.8
54
14
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
29.6
87.3
59
22
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
17.5
86.0
73
47
D33.08
ICD-10 Finland
Another benign tumor of the cerebral ventricle
+∞
85.5
80
*
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
17.3
83.3
71
46
D33.05
ICD-10 Finland
Other lateral benign tumor in temporal lobe
+∞
73.4
69
*
ZXC95
NOMESCO Finland
Use of surgical navigator
20.3
69.0
54
29
AA1AD
NOMESCO Finland
CT of head and brain
4.1
63.7
290
1110
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
87.7
57.2
63
8
G40.9
ICD-10 Finland
Epilepsy, unspecified
9.0
56.7
74
92
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
15.0
55.1
50
36
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
20.0
54.9
43
23
D33.30
ICD-10 Finland
Acoustic neuroma
75.0
54.3
61
9
XA800
NOMESCO Finland
Neuropsychological investigation
6.9
50.7
84
137
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
20.8
50.6
39
20
XCK00
NOMESCO Finland
Perimetry
6.1
46.2
87
161
D33.0
ICD-10 Finland
Benign neoplasm: Brain, supratentorial
+∞
45.4
43
*
G91.1
ICD-10 Finland
Obstructive hydrocephalus
75.8
43.7
49
7
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.8
43.0
169
564
H53.4
ICD-10 Finland
Visual field defects
10.7
42.1
47
47
R56.8
ICD-10 Finland
Other and unspecified convulsions
5.7
42.1
85
168
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
15.4
39.4
35
24
N03AG01
ATC
valproic acid; systemic, rectal
4.9
36.1
86
196
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
10.9
31.8
35
34
D33.04
ICD-10 Finland
Temporal lobe
+∞
31.5
30
*
183
Kela drug reimbursment
Lamotrigin and topiramate
12.0
31.1
32
28
H02AB02
ATC
dexamethasone; systemic
3.5
29.5
116
380
N03AB02
ATC
phenytoin; systemic
9.9
29.1
34
36
R51.80
ICD-10 Finland
Headache
2.9
28.2
167
696
D33.03
ICD-10 Finland
Pilosytic lateral astrocytoma of the strobe brain
+∞
27.3
26
*
N03AF01
ATC
carbamazepine; oral, rectal
4.9
27.3
64
143
WX882
NOMESCO Finland
High dependency care
6.9
27.2
43
66
D33.01
ICD-10 Finland
Medial ganglion glioma of the cerebrum
+∞
26.2
25
*
D32.9
ICD-10 Finland
Benign neoplasm: Meninges, unspecified
42.1
26.1
32
8
D33.9
ICD-10 Finland
Benign neoplasm: Central nervous system, unspecified
141.0
25.8
27
*
H02AB09
ATC
hydrocortisone; systemic
6.5
23.9
40
65
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.7
23.8
160
706
N03AX18
ATC
lacosamide; systemic
20.5
23.7
35
18
D32.0
ICD-10 Finland
Benign neoplasm: Cerebral meninges
52.0
21.3
25
5
D33.2
ICD-10 Finland
Benign neoplasm: Brain, unspecified
52.0
21.3
25
5
D32.01
ICD-10 Finland
Benign tumor of meninges on interhemispheric surface
24.4
20.1
28
12
G93.0
ICD-10 Finland
Cerebral cysts
37.1
20.0
25
7
D33.06
ICD-10 Finland
Plexus papilloma of the ventricle of the brain
+∞
19.9
19
*
L01AX03
ATC
temozolomide; systemic
22.5
19.7
28
13
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
3.1
19.3
88
312
E23.00
ICD-10 Finland
Panhypopituitarism
56.9
19.0
22
*
ZXE20
NOMESCO Finland
More than three and less than five hours
2.8
19.0
112
458
D33.7
ICD-10 Finland
Benign neoplasm: Other specified parts of central nervous system
195.8
18.6
19
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
18.4
190
1008
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
15.4
17.3
28
19
Z2445
NOMESCO Finland
Psychologist
3.9
17.0
53
147
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
22.6
17.0
24
11
AA1BD
NOMESCO Finland
Extensive CT of head and brain
5.9
17.0
31
55
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
92.6
16.6
18
*
AAF99
NOMESCO Finland
Other shunt operation on ventricle of brain or intracerebral cyst
92.6
16.6
18
*
C71.11
ICD-10 Finland
Malignant tumor of frontal lobe grade II glioma
61.7
15.8
18
*
9530/0-C70.9
ICD-O-3
Meningioma, NOS, of meninges, NOS
164.0
15.5
16
*
N88
ICPC
Epilepsy
16.6
15.3
24
15
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.1
15.3
68
237
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
12.2
15.2
27
23
9560/0-C72.4
ICD-O-3
Schwannoma, NOS, of acoustic nerve
46.2
15.1
18
*
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
17.0
14.9
23
14
G40.10
ICD-10 Finland
Simple partial seizures
19.0
14.8
22
12
2152
FHL
Extraction, big brain
153.5
14.5
15
*
C71.10
ICD-10 Finland
Malignant tumor in frontal lobe without histology
27.9
14.3
19
7
H53.2
ICD-10 Finland
Diplopia
4.5
14.0
35
82
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.8
13.9
73
279
C71.20
ICD-10 Finland
Malignant tumor in temporal lobe without histology
54.6
13.9
16
*
C71.90
ICD-10 Finland
Malignant tumor in unspecified localization in the brain without histology
54.6
13.9
16
*
N76
ICPC
Neoplasm nervous system unspecified
76.9
13.6
15
*
9505/1-C71.9
ICD-O-3
Ganglioglioma, NOS, of brain, NOS
+∞
13.6
13
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
13.5
240
1527
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.7
13.3
77
310
D32.03
ICD-10 Finland
Benign meningioma in ventricles
41.0
13.2
16
*
101
Kela drug reimbursment
Anterior pituitary hypofunction
15.5
13.2
21
14
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.2
13.0
53
175
H47.2
ICD-10 Finland
Optic atrophy
29.1
13.0
17
6
ZXC40
NOMESCO Finland
Use of ultrasound
13.4
13.0
22
17
D43.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Central nervous system, unspecified
51.1
12.9
15
*
C71.29
ICD-10 Finland
Malignant tumor in temporal lobe other or unspecified histology
+∞
12.5
12
*
9421/1-C71.9
ICD-O-3
Pilocytic astrocytoma of brain, NOS
+∞
12.5
12
*
AWB00
NOMESCO Finland
Reoperation for superficial infection in surgery of the nervous system
132.6
12.5
13
*
AAG00
NOMESCO Finland
Stereotactic intracranial biopsy
38.4
12.3
15
*
R42
ICD-10 Finland
Dizziness and giddiness
2.0
12.2
155
872
AAF00
NOMESCO Finland
Ventriculostomy
18.5
12.1
18
10
DE2CG
NOMESCO Finland
Acoustic channel extensive MRI examination with high intensity magnet
10.3
12.1
23
23
G91.0
ICD-10 Finland
Communicating hydrocephalus
21.8
12.1
17
8
N29
ICPC
Neurological sympt/complt other
5.8
12.0
22
39
ZXE10
NOMESCO Finland
More than one and less than three hours
1.9
12.0
223
1428
N05BA09
ATC
clobazam; oral
12.0
11.9
21
18
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.4
11.8
85
379
TAB00
NOMESCO Finland
Lumbar puncture
3.2
11.8
47
153
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
16.8
11.7
18
11
ZXC86
NOMESCO Finland
Use of endoscopic device
30.7
11.7
15
5
CBK11
NOMESCO Finland
Operation for lagophtalmus with implant
+∞
11.5
11
*
D33.37
ICD-10 Finland
Another benign tumor of the cranial nerves
+∞
11.5
11
*
D33.3
ICD-10 Finland
Benign neoplasm: Cranial nerves
+∞
11.5
11
*
ABB00
NOMESCO Finland
Excision of lesion of spinal canal
122.2
11.5
12
*
Z3226
NOMESCO Finland
Physiotherapist
2.1
11.4
125
665
Z3229
NOMESCO Finland
Other healthcare associate professional
2.7
11.0
64
258
R4150
NOMESCO Finland
Neuropsychological rehabilitation
9.8
10.8
21
22
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
21.9
10.7
15
7
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
10.3
10.6
20
20
N75
ICPC
Benign neoplasm nervous system
111.9
10.4
11
*
D33.39
ICD-10 Finland
Benign tumor of the cranial nerves UNS
111.9
10.4
11
*
C71.21
ICD-10 Finland
Malignant tumor of temporal lobe grade II glioma
111.9
10.4
11
*
D43.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, infratentorial
111.9
10.4
11
*
C71.50
ICD-10 Finland
Malignant tumor of cerebral ventricle without histology
+∞
10.4
10
*
D33.10
ICD-10 Finland
Benign pilosytic astrocytoma of brain stem
+∞
10.4
10
*
2250A
ICD-9 Finland
Benign neoplasm of brain and other parts of nervous system, Brain
+∞
10.4
10
*
H02.2
ICD-10 Finland
Lagophthalmos
33.1
10.4
13
*
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
9.8
10.3
20
21
G40.21
ICD-10 Finland
Partial epileptic seizure with cloudiness and automatism
19.2
10.3
15
8
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
7.7
10.3
23
31
R51
ICD-10 Finland
Headache
2.9
10.2
48
173
130
Kela drug reimbursment
Malignant tumour
2.6
10.0
61
251
C71.00
ICD-10 Finland
Malignant tumor of the cerebrum except lobes and ventricles without histology
40.8
10.0
12
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.1
9.9
108
572
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.4
9.9
70
310
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
26.5
9.8
13
5
R4110
NOMESCO Finland
Physiotherapy
1.8
9.8
176
1103
N03AX09
ATC
lamotrigine; oral
2.9
9.7
46
166
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
11.6
9.6
17
15
D32.04
ICD-10 Finland
Secondary or multiple benign tumor of the meninges above the exam
30.5
9.4
12
*
D43.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, unspecified
30.5
9.4
12
*
9413/0-C71.9
ICD-O-3
Dysembryoplastic neuroepithelial tumor of brain, NOS
+∞
9.4
9
*
2252A
ICD-9 Finland
Benign neoplasm of brain and other parts of nervous system, Cerebral meninges
+∞
9.4
9
*
Z3231
NOMESCO Finland
Registered nurse
1.8
9.2
175
1113
G40
ICD-10 Finland
Epilepsy
7.9
9.2
20
26
WF099
NOMESCO Finland
Other radiotherapy
15.9
9.1
14
9
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.0
9.1
106
575
C71.12
ICD-10 Finland
Malignant tumor of frontal lobe grade III glioma
37.3
9.0
11
*
Q28.3
ICD-10 Finland
Other malformations of cerebral vessels
24.4
8.9
12
5
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
3.4
8.9
32
98
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
20.4
8.5
12
6
G41.9
ICD-10 Finland
Status epilepticus, unspecified
20.4
8.5
12
6
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.1
8.5
36
122
WF002
NOMESCO Finland
Radical radiotherapy
2.8
8.4
42
156
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
6.9
8.4
20
30
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
8.4
129
766
D33.11
ICD-10 Finland
Brain stem
+∞
8.3
8
*
AAJ20
NOMESCO Finland
Excision of epileptic focus
+∞
8.3
8
*
H01AC01
ATC
somatropin; parenteral
14.7
8.2
13
9
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
2.0
8.1
104
581
G40.09
ICD-10 Finland
Other or unspecified partial (focal) idiopathic epilepsy or epileptic syndrome with local onset
17.5
8.1
12
7
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
4.2
8.1
21
51
G51.0
ICD-10 Finland
Bell palsy
3.9
8.0
23
60
XKD00
NOMESCO Finland
Uroflowmetry
2.1
8.0
85
445
G40.11
ICD-10 Finland
Simple partial epileptic seizure that develops into a complex partial seizure
13.2
7.9
13
10
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
11.0
7.8
14
13
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.0
7.7
92
501
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.2
7.5
69
341
D32.05
ICD-10 Finland
Cerebral meninges
81.0
7.4
8
*
E22.80
ICD-10 Finland
Central precocious puberty
81.0
7.4
8
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
9.5
7.3
14
15
D42.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Cerebral meninges
+∞
7.3
7
*
9505/1-C71.2
ICD-O-3
Ganglioglioma, NOS, of temporal lobe
+∞
7.3
7
*
D32.06
ICD-10 Finland
Benign tumor of the meninges os petrosum or clivus area
+∞
7.3
7
*
D32.1
ICD-10 Finland
Benign neoplasm: Spinal meninges
+∞
7.3
7
*
AAA10
NOMESCO Finland
Biopsy through craniotomy
+∞
7.3
7
*
Q85.01
ICD-10 Finland
Neurofibromatosis, type 2
+∞
7.3
7
*
N03AX23
ATC
brivaracetam; systemic
16.0
7.2
11
7
N05AX08
ATC
risperidone; systemic
2.2
7.2
61
291
301
Kela drug reimbursment
Growth hormone
30.4
7.2
9
*
D32.07
ICD-10 Finland
Secondary or multiple benign tumor of the meninges below the exam
30.4
7.2
9
*
CS494
NOMESCO Finland
Other visual field testing
3.6
7.1
23
66
WX872
NOMESCO Finland
Intensive care
2.8
6.9
33
120
N03AX11
ATC
topiramate; oral
3.3
6.9
25
77
D35.30
ICD-10 Finland
Craniopharyngoma
40.5
6.8
8
*
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
6.8
439
3726
A02BC02
ATC
pantoprazole; systemic
1.6
6.7
394
3264
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
4.1
6.7
18
45
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
6.6
137
883
D18.0
ICD-10 Finland
Haemangioma, any site
3.7
6.6
21
59
G40.39
ICD-10 Finland
Other or unspecified generalized epileptic syndromes with atonic, clonic, myoclonic or tonic-clonic seizures
12.4
6.6
11
9
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
6.5
273
2093
T85.0
ICD-10 Finland
Mechanical complication of ventricular intracranial (communicating) shunt
70.6
6.4
7
*
ZZC00
NOMESCO Finland
Graft of fascia
70.6
6.4
7
*
D33.40
ICD-10 Finland
Benign glioma of the spinal cord (grade I)
70.6
6.4
7
*
ZYC01
NOMESCO Finland
Remote contact by phone
2.3
6.3
46
206
E22.1
ICD-10 Finland
Hyperprolactinaemia
18.2
6.3
9
5
102
Kela drug reimbursment
Diabetes insipidus
18.2
6.3
9
5
G40.1
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
18.2
6.3
9
5
N03AX15
ATC
zonisamide; oral
18.2
6.3
9
5
2159
FHL
Other measure in this category
+∞
6.3
6
*
C71.59
ICD-10 Finland
Malignant tumor of cerebral ventricle other or unspecified histology
+∞
6.3
6
*
D35.59
ICD-10 Finland
Other paragangliom
+∞
6.3
6
*
AAE32
NOMESCO Finland
Translabyrinthine excision acoustic neurinome
+∞
6.3
6
*
C710, 8000, 0
ICD-O-3
+∞
6.3
6
*
C71.22
ICD-10 Finland
Malignant tumor of temporal lobe grade III glioma
+∞
6.3
6
*
D44.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pineal gland
+∞
6.3
6
*
2251A
ICD-9 Finland
Benign neoplasm of brain and other parts of nervous system, Cranial nerves
+∞
6.3
6
*
C71.40
ICD-10 Finland
Malignant tumor of the occipital lobe without histology
+∞
6.3
6
*
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
27.0
6.2
8
*
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
12.7
6.1
10
8

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
167
570
3.65
40.87
7.1
9.2
1.09
0.99
mmol/l
0.15
128
483
168
583
3.59
40.00
7.1
9.1
7.41
7.42
ph
0.17
110
326
167
582
3.57
39.45
7.1
9.0
5.06
5.14
kpa
0.58
159
563
167
582
3.57
39.45
7.1
9.0
15.80
12.50
kpa
6.90
158
566
61
128
5.18
27.99
2.3
1.7
2488.14
134.36
e6/l
0.80
49
100
60
126
5.17
27.50
2.2
1.7
15.32
16.33
e6/l
0.03
47
96
56
116
5.21
26.04
2.3
1.7
—
—
—
0
0
389
2585
2.39
23.19
8.7
7.4
1.20
1.21
mmol/l
1.73
365
2236
36
54
7.02
23.19
1.9
2.1
—
—
—
0
0
361
2326
2.35
23.09
8.2
6.8
1.20
1.21
mmol/l
3.97
345
2150
56
130
4.64
22.74
2.0
1.6
3.53
3.66
mmol/l
0.33
51
122
106
428
2.79
18.39
1.2
1.4
—
—
—
0
0
427
3124
2.21
17.88
6.7
5.3
6.35
6.61
mmol/l
2.43
413
2939
260
1593
2.10
17.26
3.0
2.1
321.56
225.45
u/l
0.39
251
1512
120
558
2.43
15.44
3.5
1.9
312.55
379.39
nmol/l
3.10
110
519
74
279
2.88
14.47
6.5
5.9
—
—
—
0
0
30
63
4.96
13.68
2.1
2.2
—
—
—
0
0
213
1304
1.97
13.42
2.4
2.3
—
—
—
0
0
217
1339
1.96
13.35
4.1
4.1
93.45
90.95
%
0.94
211
1322
33
77
4.47
13.28
5.1
5.5
374.71
380.48
umol/l
0.07
28
69
259
1719
1.88
12.62
2.5
2.3
—
—
—
0
0
338
2484
1.81
11.45
2.8
2.8
—
—
estimate
—
0
0
141
789
2.02
11.21
2.3
2.1
28.60
29.49
s
0.65
141
773
26
67
4.01
9.22
1.6
1.6
17.05
28.96
ng/l
1.33
26
67
86
458
2.02
7.69
6.0
7.5
8.58
9.31
mmol/l
0.39
81
438
87
467
2.01
7.61
9.4
9.6
—
—
—
0
0
294
2245
1.60
7.38
5.2
5.0
35.80
36.14
g/l
0.47
280
2119
276
2086
1.59
7.17
2.4
2.1
—
—
—
0
0
46
199
2.42
6.84
2.7
1.4
7.71
9.18
u/l
0.31
37
150
477
4135
1.70
6.76
5.4
4.3
14.48
14.66
pmol/l
0.85
448
3772
379
3109
1.58
6.72
11.3
10.0
4.24
4.07
e9/l
0.64
323
2715
20
54
3.80
6.69
1.8
1.4
—
—
nmol/l
—
0
0
303
2366
1.56
6.67
11.2
12.3
1.18
1.21
inr
0.36
263
1954
17
31
5.61
6.34
1.1
1.2
0.59
0.50
ratio
—
10
16
343
2787
1.52
6.08
7.9
6.6
0.56
0.57
e9/l
0.52
286
2389
342
2778
1.52
6.06
7.3
6.5
9.97
11.67
umol/l
3.44
324
2653
352
2889
1.51
5.85
8.1
6.9
0.18
0.19
e9/l
0.52
299
2520
348
2854
1.51
5.77
8.0
6.7
1.82
1.96
e9/l
1.39
293
2516
459
3998
1.59
5.75
9.3
8.0
77.95
79.65
u/l
0.40
441
3791
211
1562
1.54
5.69
4.8
4.0
7.40
7.40
ph
0.10
165
1101
21
67
3.21
5.51
1.4
1.4
281.19
278.26
mosm/kgh2o
0.25
16
50
340
2797
1.49
5.41
8.0
6.6
0.04
0.04
e9/l
0.29
285
2402
208
1557
1.51
5.24
3.7
2.8
—
—
—
0
0
248
1951
1.46
4.77
3.8
3.7
34.44
64.94
ng/l
0.49
173
1332
66
381
1.82
4.64
2.5
2.4
8.97
15.42
au/ml
—
6
36
126
867
1.57
4.60
3.8
3.7
0.83
0.82
mmol/l
0.77
121
822
347
2919
1.44
4.59
4.7
3.7
0.00
0.54
estimate
0.51
54
565
296
2421
1.43
4.56
2.6
2.5
74.26
75.19
nmol/l
0.27
273
2189
210
1618
1.45
4.44
7.1
6.3
—
—
—
0
0
19
66
2.94
4.37
2.1
1.3
0.67
0.53
nmol/l
0.52
19
60
562
5250
1.86
4.36
20.5
14.8
24.45
22.97
mg/l
0.51
498
4281
74
457
1.70
4.14
2.6
2.8
10.25
10.42
g/l
0.13
69
423
340
2886
1.40
4.06
4.7
3.7
0.00
5.17
estimate
0.80
58
606
338
2868
1.40
4.03
4.7
3.6
0.00
0.00
estimate
-0.00
55
600
168
2165
0.69
3.99
2.9
3.0
—
—
—
0
0
225
1786
1.41
3.95
3.3
3.4
2.35
2.36
mmol/l
0.84
199
1635
397
3479
1.40
3.82
5.6
4.4
207.20
1159.96
e6/l
—
5
56
102
701
1.55
3.71
6.5
6.1
1.06
1.04
mmol/l
0.22
89
650
83
547
1.60
3.62
4.9
4.4
7.38
7.38
ph
0.04
45
327
7
9
7.85
3.56
1.1
1.0
—
—
—
0
0
526
4885
1.55
3.47
6.2
5.3
1.96
1.88
mu/l
0.21
495
4522
201
1600
1.38
3.37
5.0
3.8
0.00
0.01
estimate
1.15
53
570
79
524
1.58
3.36
4.9
4.4
1.69
1.58
mmol/l
0.12
73
449
226
1836
1.37
3.33
8.5
6.4
—
—
—
0
0
6
7
8.64
3.27
1.3
1.1
2.35
7.54
nmol/l
—
6
7
51
304
1.74
3.26
2.6
1.4
24.02
23.14
iu/l
0.06
43
248
165
1279
1.40
3.22
5.1
3.7
1.02
1.02
kg/l
0.23
119
845
408
3641
1.36
3.19
5.3
4.4
—
3.01
—
0
9
134
1003
1.43
3.19
2.8
2.7
2.42
2.44
mmol/l
1.78
120
904
17
67
2.58
3.15
2.1
2.1
—
—
—
0
0
8
16
5.05
3.06
1.9
2.3
26.89
19.06
umol/l
—
8
16
156
1209
1.39
3.03
2.9
2.6
4.38
5.90
e6/l
0.73
144
1099
5
5
10.07
2.98
1.2
1.0
—
—
—
0
0
568
5410
1.69
2.91
17.5
13.0
—
—
—
0
0
100
725
1.45
2.81
1.7
1.6
—
—
—
0
0
400
3599
1.32
2.72
4.0
3.9
—
0.38
—
0
8
87
620
1.47
2.67
1.7
1.7
—
—
—
0
0
270
2308
1.30
2.66
4.6
3.3
6.45
6.19
ph
2.68
148
1316
67
456
1.53
2.57
4.0
4.2
7.36
7.35
ph
0.22
54
325
59
391
1.56
2.55
3.3
2.4
6.73
6.57
ug/l
0.03
52
352
201
1661
1.31
2.51
3.0
2.5
60.86
61.74
u/l
0.06
184
1551
67
460
1.51
2.48
3.0
2.4
12.67
13.13
nmol/l
0.16
62
423
108
813
1.40
2.47
1.9
1.7
1122.37
1180.02
nmol/l
0.31
87
620
297
2588
1.29
2.47
8.2
6.7
0.66
0.68
%
0.19
277
2431
298
2599
1.29
2.46
8.1
6.7
8.80
8.79
%
0.03
278
2451
173
1404
1.32
2.45
4.7
4.3
—
—
—
0
0
46
290
1.63
2.44
3.9
3.6
0.70
0.61
%
0.59
46
290
262
2252
1.29
2.41
2.3
2.0
94.23
95.97
pmol/l
0.24
135
1193
5
8
6.29
2.37
1.4
7.4
—
—
—
0
0
238
2024
1.29
2.37
4.7
3.9
152.61
89.75
e6/l
0.25
174
1417
70
492
1.48
2.32
2.2
2.0
0.13
0.03
estimate
—
8
108
296
2593
1.27
2.31
8.1
6.6
2.69
2.83
%
0.42
276
2440
572
5497
1.62
2.31
14.6
11.6
26.76
26.47
u/l
0.13
560
5357
133
1047
1.35
2.31
3.3
2.9
529.33
537.07
mosm/kgh2o
0.15
119
916
6
13
4.65
2.27
1.5
1.1
—
—
—
0
0
401
3657
1.28
2.21
4.3
3.3
51.30
43.23
u/l
1.15
388
3476
179
1481
1.29
2.18
1.8
1.6
20.93
20.27
nmol/l
0.18
155
1254
64
449
1.48
2.15
2.0
2.4
0.30
0.25
e6/l
0.27
64
429
32
190
1.72
2.14
2.7
1.8
1.60
3.22
ug/l
0.45
25
166
207
1749
1.28
2.13
4.1
3.3
34.56
82.22
e6/l
0.62
168
1339
105
807
1.36
2.13
1.4
1.4
361.60
538.60
titre
1.32
25
172
37
233
1.63
2.01
2.1
1.9
—
—
—
0
0
13
57
2.31
1.99
3.0
3.2
—
—
—
0
0
60
424
1.46
1.96
2.5
2.2
6.19
6.14
ph
0.15
39
279
18
92
1.99
1.92
1.3
1.2
4.27
3.90
u/ml
0.06
11
42
21
114
1.87
1.89
2.0
1.4
0.23
0.33
nmol/l
0.69
14
89
15
72
2.11
1.87
1.3
1.2
—
—
—
0
0
295
2628
1.24
1.86
7.8
6.5
57.92
56.85
%
0.83
279
2515
298
2661
1.23
1.83
8.0
6.6
27.36
28.29
%
0.79
280
2537
169
1417
1.27
1.82
2.9
2.2
2.59
2.81
mg/l
0.77
145
1230
28
446
0.61
1.81
4.8
3.7
—
—
—
0
0
16
296
0.53
1.78
1.4
1.7
—
—
—
0
0
38
557
0.66
1.70
1.3
1.4
—
—
—
0
0
8
31
2.60
1.66
1.1
1.1
1.08
1.05
ratio
—
8
26
15
76
2.00
1.65
1.1
1.2
—
—
—
0
0
216
1883
1.23
1.62
3.8
3.2
28.49
32.50
u/l
1.35
200
1797
5
14
3.59
1.62
1.0
1.6
—
—
—
0
0
157
1325
1.25
1.59
2.6
2.9
329.65
342.45
umol/l
0.84
142
1182
85
665
1.32
1.55
1.2
1.3
—
—
—
0
0
106
857
1.29
1.53
4.0
3.0
2.04
2.43
e6/l
0.25
56
422
41
284
1.48
1.52
3.4
4.1
—
—
—
0
0
175
1502
1.23
1.51
4.2
3.1
0.33
0.33
e6/l
0.02
134
1100
187
1620
1.22
1.48
1.4
1.5
—
—
—
0
0
277
2494
1.20
1.47
11.8
11.2
0.00
0.00
e9/l
0.33
211
2041
123
1019
1.26
1.46
1.7
1.7
—
—
—
0
0
11
213
0.51
1.44
1.1
1.1
1.45
1.54
g/l
0.98
11
213
7
29
2.43
1.39
1.0
1.0
1556.74
1485.59
miu/ml
—
7
29
6
23
2.62
1.37
1.3
1.1
—
—
—
0
0
6
23
2.62
1.37
1.3
1.1
—
—
—
0
0
6
23
2.62
1.37
1.3
1.1
—
—
—
0
0
11
54
2.06
1.33
1.5
1.4
2.89
2.80
g/l
0.06
11
39
11
54
2.06
1.33
1.5
1.4
—
—
—
0
0
11
54
2.06
1.33
1.5
1.4
6.95
6.38
g/l
0.12
11
40
119
993
1.25
1.33
4.0
3.8
95.94
298.06
ng/l
2.34
87
726
12
219
0.54
1.32
1.4
1.1
0.86
0.89
g/l
0.17
12
219
586
5733
1.52
1.29
32.1
22.6
4.49
4.52
e12/l
0.86
580
5622
5
18
2.79
1.28
2.2
2.8
7.24
9.39
mg/l
—
5
13
51
381
1.37
1.28
4.7
4.0
87.00
77.63
ng/l
0.28
40
338
12
62
1.95
1.28
1.1
1.2
—
—
—
0
0
586
5735
1.51
1.26
32.2
22.7
6.90
6.71
e9/l
1.44
581
5621
293
2677
1.18
1.26
3.5
3.0
107.39
105.52
ug/l
0.07
273
2518
33
466
0.69
1.26
1.4
1.7
3.13
3.40
mmol/l
0.67
17
322
75
596
1.29
1.25
2.7
3.0
1.88
1.78
%
0.37
64
540
62
481
1.32
1.23
1.6
1.5
—
—
—
0
0
36
255
1.44
1.23
1.7
2.0
3.55
8.30
iu/ml
—
8
64
58
446
1.33
1.22
2.9
3.0
65.77
70.32
e9/l
0.50
44
327
10
49
2.06
1.22
1.1
1.2
—
—
—
0
0
22
140
1.59
1.21
4.2
2.0
—
—
—
0
0
21
133
1.60
1.19
3.0
3.2
0.27
2.13
index
2.97
11
78
105
876
1.24
1.18
3.0
2.4
13.20
13.38
umol/l
0.09
95
821
50
381
1.34
1.13
3.5
3.9
7.42
7.42
ph
0.42
39
317
10
51
1.98
1.11
6.1
3.4
1.61
6.50
nmol/l
—
10
51
63
498
1.30
1.11
3.3
2.6
0.22
0.22
g/l
0.35
57
470
167
1470
1.19
1.09
3.1
3.3
829.14
1142.50
ng/l
1.35
146
1251
141
1227
1.19
1.05
1.9
1.8
1.60
1.26
mg/l
0.55
110
950
7
34
2.07
1.03
1.1
1.2
—
—
—
0
0
33
240
1.40
1.01
2.8
2.4
—
—
—
0
0
9
48
1.89
1.00
1.0
1.1
—
—
—
0
0
123
1063
1.20
0.99
1.3
1.3
35.21
30.79
iu/ml
0.09
30
327
242
2216
1.15
0.95
4.9
3.5
0.00
0.02
estimate
1.22
47
504
81
676
1.23
0.93
5.2
3.2
3.81
4.56
e9/l
1.11
68
599
9
52
1.74
0.92
1.0
1.2
—
—
—
0
0
33
246
1.36
0.89
4.4
3.3
1.02
1.02
ratio
0.11
25
232
32
238
1.36
0.88
3.5
1.7
—
—
—
0
0
80
672
1.22
0.87
1.5
1.5
—
—
—
0
0
89
756
1.21
0.87
3.1
2.4
20.84
22.90
%
0.87
81
713
50
398
1.28
0.87
2.0
3.0
67.54
66.92
g/l
0.25
44
368
190
1722
1.15
0.85
3.6
3.6
—
0.71
—
0
7
148
1654
0.86
0.85
3.8
3.0
0.00
0.06
estimate
0.60
47
488
26
188
1.40
0.84
1.2
1.3
—
—
—
0
0
0
25
0.00
0.79
0.0
1.4
—
102.74
—
0
17
0
27
0.00
0.77
0.0
1.6
—
1.09
—
0
19
0
28
0.00
0.76
0.0
1.4
—
7.33
—
0
17
41
327
1.27
0.72
2.1
2.8
—
—
—
0
0
21
152
1.40
0.70
1.1
1.2
0.97
3.00
u/ml
1.20
15
86
116
1030
1.16
0.70
1.6
1.7
437.59
19217929.75
pmol/l
0.72
101
869
7
42
1.67
0.68
5.1
2.7
1099.71
853.93
mg
—
7
42
14
94
1.50
0.67
1.0
1.1
0.04
0.14
u/ml
—
7
30
5
29
1.73
0.64
1.6
1.8
3.40
7.72
nmol/l
—
5
24
8
49
1.64
0.62
11.6
3.4
31.51
50.97
u/ml
—
8
49
33
263
1.27
0.61
1.8
2.3
7770.88
5550.35
u/l
—
6
111
110
984
1.14
0.60
1.3
1.3
4.51
11.04
u/ml
1.32
45
379
0
23
0.00
0.58
0.0
1.6
—
0.51
—
0
23
0
23
0.00
0.58
0.0
1.2
—
181.54
—
0
23
20
149
1.35
0.58
1.3
1.2
—
—
—
0
0
8
55
1.46
0.56
7.9
6.8
13.99
10.89
%
—
8
55
33
267
1.25
0.55
2.6
2.0
0.14
2.73
estimate
—
7
92
16
116
1.39
0.55
1.3
2.1
140.50
128.92
g/l
—
10
91
50
424
1.20
0.54
1.2
1.3
182.34
168.03
u/ml
0.08
20
184
49
575
0.84
0.54
1.5
1.5
—
—
—
0
0
54
462
1.19
0.53
5.3
5.5
0.00
0.13
%
0.98
20
107
11
156
0.70
0.50
1.5
1.6
—
—
—
0
0
67
760
0.87
0.49
1.4
1.5
—
—
—
0
0
92
827
1.13
0.49
3.0
2.4
2.37
2.34
g/l
0.22
82
766
28
226
1.25
0.49
1.4
1.4
195.45
244.64
miu/ml
0.24
11
112
37
310
1.21
0.47
1.4
1.2
—
—
—
0
0
7
49
1.43
0.46
2.1
2.2
30.80
41.79
%
—
7
49
55
479
1.16
0.46
1.2
1.2
—
—
—
0
0
39
330
1.19
0.45
2.8
3.2
243.76
178.37
ng/l
0.27
33
293
11
152
0.72
0.44
1.5
1.5
—
—
—
0
0
17
130
1.32
0.44
1.0
1.1
0.25
0.96
u/ml
—
9
63
6
92
0.65
0.42
1.2
1.1
—
—
—
0
0
8
57
1.41
0.42
2.5
1.8
90.98
90.07
%
—
8
57
52
455
1.16
0.41
4.2
4.9
0.65
0.53
%
0.23
23
132
5
33
1.52
0.41
4.0
3.1
0.80
0.82
index
—
5
33
0
15
0.00
0.41
0.0
1.7
—
1.17
—
0
10
0
16
0.00
0.41
0.0
1.7
—
57.40
—
0
10
5
34
1.47
0.40
1.6
3.5
6.58
7.79
mmol/l
—
5
34
503
4941
1.10
0.38
5.5
4.9
5.74
5.89
mmol/l
2.30
465
4553
33
280
1.19
0.38
3.6
1.8
—
—
—
0
0
80
727
1.12
0.37
1.2
1.2
—
—
—
0
0
9
69
1.31
0.37
1.6
1.2
—
—
—
0
0
17
134
1.28
0.37
1.0
1.1
1.27
4.78
u/ml
—
10
79
12
90
1.34
0.36
3.6
3.2
4.00
4.20
e9/l
0.14
12
90
68
614
1.12
0.36
1.4
1.3
—
—
—
0
0
6
43
1.40
0.35
1.5
1.3
—
—
—
0
0
6
44
1.37
0.34
1.2
1.2
91.33
105.20
pmol/l
—
6
44
6
44
1.37
0.34
3.3
2.8
—
—
—
0
0
84
770
1.11
0.34
2.4
2.1
—
—
—
0
0
14
109
1.29
0.33
1.3
1.7
—
—
—
0
0
14
110
1.28
0.32
1.0
1.1
1.35
2.28
u/ml
—
8
54
13
101
1.29
0.32
3.8
3.1
—
—
—
0
0
19
156
1.22
0.31
7.8
9.9
—
—
—
0
0
57
516
1.12
0.30
3.6
2.4
45.74
31.12
u/l
0.72
47
429
156
1480
1.07
0.30
5.5
5.4
3.84
2.43
ug/l
0.55
141
1332
13
102
1.28
0.30
1.0
1.1
2.33
3.93
u/ml
—
8
43
131
1235
1.08
0.30
2.0
2.1
—
—
—
0
0
28
241
1.17
0.29
1.2
1.3
—
—
—
0
0
135
1277
1.07
0.28
5.4
4.8
—
—
—
0
0
50
451
1.12
0.28
4.7
5.1
0.00
0.13
%
2.66
19
119
19
158
1.21
0.28
1.5
1.4
267.33
315.13
ug/g
—
9
89
10
76
1.32
0.28
1.0
1.3
—
98.12
—
0
6
170
1623
1.07
0.27
3.8
3.5
48.23
53.14
mg/l
0.11
122
1063
34
300
1.14
0.27
1.0
1.1
—
—
—
0
0
8
66
1.21
0.27
1.6
2.7
—
—
—
0
0
12
95
1.27
0.26
1.3
1.6
—
—
—
0
0
53
483
1.11
0.26
3.3
4.5
46.93
31.64
ug/l
0.13
42
390
23
198
1.17
0.25
8.8
5.0
1.28
1.39
mg/l
0.47
23
178
34
303
1.13
0.24
3.5
1.8
—
—
—
0
0
228
2206
1.05
0.23
1.9
2.0
1.50
1.36
mmol/l
1.09
196
1877
34
304
1.13
0.23
3.5
1.8
—
—
—
0
0
189
1821
1.05
0.23
4.6
3.4
7.33
7.87
mmol/l
0.93
170
1562
5
41
1.22
0.22
1.2
1.2
2387.20
216931.72
e6/l
—
5
29
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.7
—
1.21
—
0
11
0
10
0.00
0.21
0.0
1.3
—
1.80
—
0
10
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
1.68
—
0
6
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
51
1.18
0.19
1.0
1.1
—
—
—
0
0
6
52
1.16
0.19
2.7
2.4
—
—
—
0
0
16
137
1.17
0.19
1.6
1.4
—
—
—
0
0
6
53
1.13
0.18
1.0
1.1
—
—
—
0
0
23
204
1.13
0.18
6.8
2.1
—
—
—
0
0
18
157
1.15
0.17
2.3
2.1
3.70
4.96
iu/l
—
9
59
33
301
1.10
0.17
3.6
1.8
—
—
—
0
0
7
63
1.11
0.17
1.0
1.1
—
—
—
0
0
51
477
1.08
0.16
4.6
4.9
0.40
0.89
%
2.36
20
147
11
92
1.20
0.16
1.0
1.1
—
—
—
0
0
29
266
1.09
0.14
1.4
1.5
0.34
0.29
mg/l
—
10
112
20
180
1.11
0.13
1.2
1.2
—
2.63
—
0
18
11
94
1.17
0.13
2.0
1.8
—
—
—
0
0
26
239
1.09
0.12
1.0
1.1
—
—
—
0
0
65
621
1.05
0.12
3.1
2.9
7.70
7.96
umol/l
0.04
53
558
21
191
1.10
0.12
2.1
1.9
37.62
39.56
nmol/l
0.16
21
183
11
95
1.16
0.11
1.3
1.2
—
—
—
0
0
506
5094
0.96
0.11
5.2
5.0
4.67
4.63
mmol/l
0.32
482
4776
16
143
1.12
0.11
2.3
4.1
1.29
2.74
ratio
1.28
11
78
170
1661
1.03
0.11
4.3
4.2
7.81
9.28
mg/mmol
0.20
114
1055
11
126
0.87
0.11
8.1
4.2
—
—
—
0
0
14
157
0.89
0.11
1.1
1.1
—
—
—
0
0
10
86
1.17
0.11
1.4
1.6
—
—
—
0
0
10
86
1.17
0.11
1.4
1.6
—
—
—
0
0
10
86
1.17
0.11
1.4
1.6
—
—
—
0
0
10
86
1.17
0.11
1.4
1.6
—
—
—
0
0
12
106
1.13
0.10
2.8
4.0
20.83
28.99
mg/l
—
6
72
479
4821
0.97
0.09
6.5
6.2
37.91
38.97
mmol/mol
2.48
449
4535
69
715
0.96
0.09
1.6
1.8
—
—
—
0
0
124
1269
0.97
0.08
1.7
1.5
2.25
2.32
g/l
0.14
71
793
5
60
0.83
0.08
1.0
7.1
6.04
6.80
mmol/l
—
5
51
5
65
0.77
0.08
3.6
2.4
3.72
4.02
mmol/l
—
5
65
5
65
0.77
0.08
3.6
2.4
1.17
1.19
mmol/l
—
5
65
5
65
0.77
0.08
3.6
2.4
105.60
105.72
mmol/l
—
5
65
6
74
0.81
0.07
6.3
2.6
—
—
—
0
0
15
137
1.10
0.07
1.5
1.3
—
—
—
0
0
17
157
1.09
0.07
1.2
1.2
—
—
—
0
0
505
5073
0.97
0.07
5.1
4.8
1.48
1.46
mmol/l
0.36
477
4729
32
305
1.05
0.06
1.2
1.2
—
167.89
—
0
9
9
100
0.90
0.06
1.0
1.1
—
—
—
0
0
18
193
0.93
0.06
2.5
4.1
273.30
268.89
mg/l
—
10
87
13
141
0.92
0.05
1.5
1.1
—
—
—
0
0
21
198
1.06
0.05
1.5
1.8
—
—
—
0
0
77
753
1.03
0.05
2.8
2.5
121.27
118.13
ug/g
0.04
58
591
445
4471
0.98
0.05
25.0
18.6
13.57
13.52
%
0.29
445
4430
12
110
1.09
0.05
1.1
1.1
—
—
—
0
0
12
110
1.09
0.05
1.1
1.1
—
—
—
0
0
65
637
1.02
0.03
1.7
1.7
—
—
—
0
0
14
132
1.06
0.02
1.0
1.1
0.22
1.74
u/ml
—
9
71
486
4848
1.01
0.02
4.3
4.1
1.25
1.28
mmol/l
0.37
455
4489
144
1430
1.01
0.01
1.4
1.3
0.96
2.08
u/ml
1.18
35
383
515
5157
0.99
0.01
5.9
5.6
2.74
2.72
mmol/l
0.18
487
4822
38
374
1.02
0.00
1.3
1.2
—
—
—
0
0
12
125
0.96
0.00
3.9
3.0
58.42
57.13
%
0.12
12
125
18
184
0.98
0.00
3.1
2.7
—
—
—
0
0
20
204
0.98
0.00
3.1
3.4
190.48
1796.91
u/ml
1.13
20
175
30
303
0.99
0.00
3.9
1.8
—
—
—
0
0
15
152
0.99
0.00
1.3
1.2
—
—
—
0
0
24
238
1.01
0.00
1.3
1.3
—
—
—
0
0
88
879
1.00
0.00
3.1
3.1
0.83
0.76
ug/l
0.26
58
537
0
8
0.00
0.00
0.0
2.4
—
2.75
—
0
8
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
3.3
—
18.28
—
0
8
0
5
0.00
-0.00
0.0
2.2
—
0.44
—
0
5
6
63
0.95
-0.00
2.8
2.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
171.89
—
0
9
7
77
0.91
-0.00
1.3
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
9
93
0.97
-0.00
1.4
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
53
0.94
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
390.67
—
0
6
0
9
0.00
-0.00
0.0
1.0
—
0.02
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
244.80
—
0
5
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
4.3
—
7.04
—
0
9
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
66
0.91
-0.00
1.3
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.0
—
—
—
0
0
8
85
0.94
-0.00
1.6
1.4
—
—
—
0
0
11
110
1.00
-0.00
2.6
3.3
12.02
7.93
pmol/l
0.70
11
110
0
6
0.00
-0.00
0.0
1.0
—
18.12
—
0
6
0
5
0.00
-0.00
0.0
6.0
—
0.20
—
0
5
5
54
0.93
-0.00
1.2
2.3
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_BRAIN_SUPRATENT and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_BRAIN_SUPRATENT 1.794 [1.53, 2.1] < 0.001
Birth year 1.003 [1.0, 1.01] 0.441

During the follow-up period (1.1.1998 — 31.12.2019), 355 out of 1970 females with CD2_BENIGN_BRAIN_SUPRATENT died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_BRAIN_SUPRATENT 2.162 [1.81, 2.59] < 0.001
Birth year 0.992 [0.98, 1.0] 0.09

During the follow-up period (1.1.1998 — 31.12.2019), 363 out of 1653 males with CD2_BENIGN_BRAIN_SUPRATENT died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_BRAIN_SUPRATENT.

N-year risk Females Males
1 0.206% 0.378%
5 1.309% 2.719%
10 2.936% 7.058%
15 5.921% 13.53%
20 11.166% 22.667%

Relationships between endpoints

Index endpoint: CD2_BENIGN_BRAIN_SUPRATENT – Benign neoplasm: Brain, supratentorial

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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