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Tic and related disorders

DOID EFO Endpoint Browser PheWeb

KRA_PSY_TIC

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — F95
  • Hospital discharge: ICD-9 — 3072
  • Hospital discharge: ICD-8 — 30620
  • Cause of death: ICD-10 — F95
  • Cause of death: ICD-9 — 3072
  • Cause of death: ICD-8 — 30620

2 out of 7 registries used, show all original rules.

582

4. Check minimum number of events

None

582

5. Include endpoints

None

582

6. Filter based on genotype QC (FinnGen only)

521

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF12
Parent code in ICD-10
F90-F98
Name in latin
Perturbationes ticiformes

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 12184 3427 8742
Only index persons 9944 2898 7046
Unadjusted period prevalence (%)
Whole population 0.20 0.10 0.24
Only index persons 0.22 0.11 0.27
Median age at first event (years)
Whole population 9.93 10.84 9.52
Only index persons 10.81 12.11 10.28

-FinnGen-

Key figures

All Female Male
Number of individuals 521 276 245
Unadjusted period prevalence (%) 0.10 0.10 0.11
Median age at first event (years) 15.15 17.78 12.19

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
561
Matched controls
5610
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F95.9
ICD-10 Finland
Tic disorder, unspecified
1654.4
231.2
209
*
F95.2
ICD-10 Finland
Combined vocal and multiple motor tic disorder [de la Tourette]
+∞
217.2
194
*
F95.0
ICD-10 Finland
Transient tic disorder
449.1
113.8
110
*
N05AX08
ATC
risperidone; systemic
8.8
107.3
161
245
F95.1
ICD-10 Finland
Chronic motor or vocal tic disorder
1167.9
102.6
97
*
N05AD01
ATC
haloperidol; systemic
22.9
89.4
67
33
N05AX12
ATC
aripiprazole; systemic
8.3
84.5
128
194
N03AE01
ATC
clonazepam; systemic
9.4
59.6
76
92
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
4.0
48.4
189
638
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
5.3
36.5
80
170
F95.8
ICD-10 Finland
Other tic disorders
+∞
35.8
34
*
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
4.3
35.5
104
280
F42.9
ICD-10 Finland
Obsessive-compulsive disorder, unspecified
11.2
35.2
38
36
F90.0
ICD-10 Finland
Disturbance of activity and attention
3.6
34.3
139
470
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
4.8
33.7
84
199
F84.5
ICD-10 Finland
Asperger syndrome
9.2
33.5
42
49
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
4.2
32.3
98
270
N05BA04
ATC
oxazepam; oral
3.1
31.8
181
749
ZY010
NOMESCO Finland
Hospital outpatient
4.0
31.7
104
303
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
4.9
31.7
77
178
N06BA04
ATC
methylphenidate; oral
3.6
31.5
125
415
N06AB06
ATC
sertraline; oral
3.4
31.2
140
502
F42.2
ICD-10 Finland
Mixed obsessional thoughts and acts
8.4
30.6
41
52
30620
ICD-8 Finland
Special symptoms not elsewhere classified, Tics
+∞
30.5
29
*
N05AH04
ATC
quetiapine; oral
3.0
29.8
180
766
N05AH03
ATC
olanzapine; systemic
4.0
28.6
90
254
IBZ06
NOMESCO Finland
Evaluation concerning developmental neuropsychiatry
7.6
27.5
40
56
N06AB03
ATC
fluoxetine; oral
3.6
26.9
103
332
IGY99
NOMESCO Finland
Other psychiatric treatment contact
4.2
26.9
78
207
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
3.9
26.6
88
257
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
4.2
25.5
75
201
IGY02
NOMESCO Finland
Psychiatric monitoring contact
3.6
24.3
91
288
IFA01
NOMESCO Finland
Psychiatric pharmacotherapy plan, not specified
4.8
23.2
55
124
331
Kela drug reimbursment
Atomoxetine, dexamphetamine, guanfacine and lisdexamphetamine
4.9
23.2
54
120
N05BA01
ATC
diazepam; systemic, rectal
3.5
22.7
87
279
ZYC01
NOMESCO Finland
Remote contact by phone
3.7
21.9
76
228
N03AX09
ATC
lamotrigine; oral
4.0
21.9
67
184
N06AX16
ATC
venlafaxine; oral
3.0
21.2
113
441
IBA01
NOMESCO Finland
Diagnostic and symptom-mapping evaluation
3.8
20.5
66
188
F42.1
ICD-10 Finland
Predominantly compulsive acts [obsessional rituals]
8.7
20.3
26
31
N03AG01
ATC
valproic acid; systemic, rectal
3.9
19.9
63
177
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.7
19.8
135
598
N06AX12
ATC
bupropion; oral
3.1
19.4
89
318
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.5
19.4
151
713
N06BA09
ATC
atomoxetine; oral
7.5
19.2
28
39
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.3
19.0
77
255
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
3.7
19.0
65
193
F42.0
ICD-10 Finland
Predominantly obsessional thoughts or ruminations
7.6
18.8
27
37
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
3.7
18.5
63
186
ICB06, ,
NOMESCO Finland
5.6
18.5
36
68
IGP01
NOMESCO Finland
Psychiatric family contact
4.1
18.4
53
139
Z2445
NOMESCO Finland
Psychologist
3.1
18.1
84
302
F29
ICD-10 Finland
Unspecified nonorganic psychosis
3.7
17.8
59
171
N06AB10
ATC
escitalopram; oral
2.3
17.6
167
858
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
3.5
17.1
64
201
3072A
ICD-9 Finland
Special symptoms or syndromes not elsewhere classified, Tics[NYKIMISHÄIRIÖ, MÄÄRITTELEMÄTÖN]
+∞
16.7
16
*
N06AB04
ATC
citalopram; systemic
2.8
16.4
96
391
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
3.6
16.2
57
172
IGV01
NOMESCO Finland
Psychiatric network contact
4.4
16.1
42
102
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.9
16.0
86
335
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.7
15.6
91
369
G24.5
ICD-10 Finland
Blepharospasm
87.6
15.6
17
*
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
4.4
15.6
40
96
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
3.6
15.5
54
162
N06AB05
ATC
paroxetine; oral
4.2
15.1
42
107
N05AG02
ATC
pimozide; oral
+∞
14.6
14
*
C07AA05
ATC
propranolol; systemic
2.3
14.6
140
715
IEV99
NOMESCO Finland
Other psychiatric network intervention
5.1
14.4
31
64
N06AX26
ATC
vortioxetine; oral
2.7
14.3
82
330
N06BA12
ATC
lisdexamfetamine; oral
4.1
14.0
40
104
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.2
14.0
57
189
Z3231
NOMESCO Finland
Registered nurse
2.1
13.9
194
1145
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
4.0
13.7
40
106
ICB02
NOMESCO Finland
Psychiatric treatment plan, extended/prolonged
4.6
13.5
33
76
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
5.0
13.5
29
60
ZXY51
NOMESCO Finland
2-person team, doctor-nurse
4.4
13.3
34
81
R42
ICD-10 Finland
Dizziness and giddiness
2.4
12.8
105
500
N06AX11
ATC
mirtazapine; oral
2.0
12.6
176
1033
SPAT1240
SPAT
Therapeutic discussion
2.3
12.5
108
526
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.2
12.4
52
175
SPAT1243
SPAT
Psychiatric/psychological examination
3.3
12.4
48
154
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.4
12.3
45
139
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.4
12.0
94
437
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.8
12.0
66
259
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
5.5
11.9
23
43
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
2.8
11.8
61
232
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.9
11.7
35
94
C02AC02
ATC
guanfacine; oral
30.8
11.7
15
5
G51.3
ICD-10 Finland
Clonic hemifacial spasm
66.4
11.6
13
*
Z03.2
ICD-10 Finland
Observation for suspected mental and behavioural disorders
3.8
11.5
36
100
N03AF01
ATC
carbamazepine; oral, rectal
4.9
11.3
25
53
F93.89
ICD-10 Finland
Other childhood emotional disorders
3.8
11.2
35
97
N03AX12
ATC
[U] gabapentin; oral
2.6
11.1
67
276
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.1
10.9
131
723
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
4.9
10.8
24
51
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.8
10.8
57
219
F95
ICD-10 Finland
Tic disorders
112.0
10.5
11
*
N06AA04
ATC
clomipramine; systemic
8.4
10.4
22
27
Z2446
NOMESCO Finland
Social worker
2.3
10.2
83
392
N05CF01
ATC
zopiclone; oral
2.1
10.1
111
592
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
3.5
9.9
35
106
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.9
9.9
166
1025
N04AA02
ATC
biperiden; systemic
9.0
9.9
20
23
N05BA12
ATC
alprazolam; oral
2.9
9.8
46
165
L01
ICPC
Neck symptom/complaint
2.1
9.8
104
547
N05CD07
ATC
temazepam; oral
3.6
9.7
33
97
G24.9
ICD-10 Finland
Dystonia, unspecified
56.0
9.7
11
*
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
9.7
125
706
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
3.0
9.7
43
150
N03AX16
ATC
[U] pregabalin
2.3
9.7
82
394
H53.1
ICD-10 Finland
Subjective visual disturbances
2.9
9.6
46
167
IBA03
NOMESCO Finland
Psychotherapy evaluation
4.6
9.6
23
52
P29
ICPC
Psychological sympt/compl other
2.1
9.5
99
516
N06AX21
ATC
duloxetine; oral
2.5
9.4
64
278
SPAT1307
SPAT
Psychosocial counselling and guidance
2.2
9.4
91
461
F84.0
ICD-10 Finland
Childhood autism
14.0
9.2
15
11
F83
ICD-10 Finland
Mixed specific developmental disorders
3.5
9.2
31
91
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
3.0
8.9
41
146
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.9
8.8
41
147
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.6
8.8
54
224
F41.8
ICD-10 Finland
Other specified anxiety disorders
2.8
8.8
45
170
ZXE01
NOMESCO Finland
Procedure duration 0 to 9 minutes
4.1
8.7
24
61
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
2.5
8.7
56
238
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
3.3
8.6
32
100
P99
ICPC
Psychological disorders other
3.2
8.6
35
116
D01
ICPC
Abdominal pain/cramps general
1.9
8.6
115
656
R25.3
ICD-10 Finland
Fasciculation
20.4
8.5
12
6
F80.1
ICD-10 Finland
Expressive language disorder
3.6
8.5
28
81
J45.9
ICD-10 Finland
Asthma, unspecified
2.0
8.4
105
584
Z00.8
ICD-10 Finland
Other general examinations
2.3
8.3
67
314
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.3
8.2
65
303
R53
ICD-10 Finland
Malaise and fatigue
1.8
8.1
148
930
F92.8
ICD-10 Finland
Other mixed disorders of conduct and emotions
10.2
8.1
15
15
P74
ICPC
Anxiety disorder/anxiety state
2.3
8.0
62
286
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
2.7
8.0
44
173
IEP99
NOMESCO Finland
Other psychiatric family intervention
3.6
7.9
26
75
P76
ICPC
Depressive disorder
2.2
7.8
65
310
XA800
NOMESCO Finland
Neuropsychological investigation
2.5
7.7
48
200
F50.9
ICD-10 Finland
Eating disorder, unspecified
3.8
7.7
23
62
F45.8
ICD-10 Finland
Other somatoform disorders
2.4
7.7
55
245
N06AA09
ATC
amitriptyline; systemic
3.2
7.7
30
97
F84.8
ICD-10 Finland
Other pervasive developmental disorders
8.2
7.6
16
20
T82
ICPC
Obesity
3.1
7.6
32
108
P10
ICPC
Stammering/stuttering/tic
18.7
7.6
11
6
SPAT1058
SPAT
PEF monitoring instruction
2.7
7.5
41
160
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.9
7.5
118
706
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.1
7.5
31
104
M79.6
ICD-10 Finland
Pain in limb
1.7
7.5
212
1501
M03BX01
ATC
baclofen; systemic
6.1
7.4
19
32
R52.2
ICD-10 Finland
Other chronic pain
3.8
7.4
22
59
N05BE01
ATC
buspirone; oral
3.8
7.4
22
59
F34.1
ICD-10 Finland
Dysthymia
3.1
7.3
31
105
F98.8
ICD-10 Finland
Other specified behavioural and emotional disorders with onset usually occurring in childhood and adolescence
6.4
7.3
18
29
G47.3
ICD-10 Finland
Sleep apnoea
2.0
7.3
82
439
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
3.4
7.2
25
75
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.8
7.1
36
135
SPAT1241
SPAT
Extensive assessment of psychosocial situation
4.1
7.1
19
47
P03
ICPC
Feeling depressed
1.8
7.0
113
680
IFA99
NOMESCO Finland
Other psychiatric pharmacotherapy service
3.5
7.0
24
71
F90.9
ICD-10 Finland
Hyperkinetic disorder, unspecified
3.4
7.0
25
76
F33.4
ICD-10 Finland
Recurrent depressive disorder, currently in remission
3.2
7.0
28
92
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
1.8
6.9
108
644
R25.8
ICD-10 Finland
Other and unspecified abnormal involuntary movements
14.0
6.9
11
8
ZXE20
NOMESCO Finland
More than three and less than five hours
2.1
6.9
64
318
F89
ICD-10 Finland
Unspecified disorder of psychological development
6.8
6.9
16
24
N02BF02
ATC
pregabalin; oral
2.7
6.9
36
138
F88
ICD-10 Finland
Other disorders of psychological development
6.2
6.8
17
28
SPAT1395
SPAT
Health check-up of persons outside student and working life
4.4
6.8
17
40
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.1
6.7
63
314
D06
ICPC
Abdominal pain localized other
2.1
6.7
63
315
C02AC01
ATC
clonidine; systemic
22.8
6.7
9
*
IAZ98
NOMESCO Finland
Other internal psychiatric consultation
5.6
6.7
18
33
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.9
6.6
92
528
A28
ICPC
Limited function/disability NOS
2.2
6.6
56
268
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.8
6.6
107
645
A01
ICPC
Pain general/multiple sites
2.2
6.5
56
270
F61.0
ICD-10 Finland
Mixed personality disorders
5.4
6.5
18
34
SPAT1389
SPAT
Visit based on need for special support
2.1
6.5
59
291
N06AX22
ATC
agomelatine; oral
3.5
6.5
22
65
R07.4
ICD-10 Finland
Chest pain, unspecified
1.8
6.4
107
650
N08
ICPC
Abnormal involuntary movements
70.6
6.4
7
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
6.4
214
1563
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.6
6.4
36
143
P27
ICPC
Fear of mental disorder
3.3
6.4
24
76
S29
ICPC
Skin symptom/complaint other
1.7
6.4
123
781
N05BA06
ATC
lorazepam; systemic, sublingual
3.3
6.3
23
71
F84.9
ICD-10 Finland
Pervasive developmental disorder, unspecified
5.6
6.3
17
31
ZXY82
NOMESCO Finland
Nurse in multidisciplinary team
5.6
6.3
17
31
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.5
6.3
38
156
N05AF01
ATC
flupentixol; systemic
11.2
6.3
11
10
N39.4
ICD-10 Finland
Other specified urinary incontinence
3.1
6.3
26
87
R03AC02
ATC
salbutamol; inhalant
1.6
6.3
311
2485
A02BA02
ATC
ranitidine; systemic
2.2
6.3
50
234
N05AF03
ATC
chlorprothixene; systemic
3.7
6.2
19
52
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
2.6
6.2
35
139
P79
ICPC
Phobia/compulsive disorder
5.1
6.2
18
36
SPAT1365
SPAT
Health check-up performed during first study year due to special need in students of upper secondary schools or vocational schools
5.8
6.2
16
28
F92.9
ICD-10 Finland
Mixed disorder of conduct and emotions, unspecified
5.8
6.2
16
28
F42
ICD-10 Finland
Obsessive-compulsive disorder
7.8
6.2
13
17
R4110
NOMESCO Finland
Physiotherapy
1.7
6.1
136
896
N07BB01
ATC
disulfiram; oral
3.2
6.1
24
78
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.5
6.1
36
147
IBB01
NOMESCO Finland
Psychiatric functioning capacity evaluation
6.8
6.1
14
21
N05AB03
ATC
perphenazine; systemic, rectal
3.4
6.1
21
63

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
87
308
3.16
19.25
2.5
2.4
—
—
—
0
0
210
1225
2.14
15.93
2.7
3.2
2.37
2.37
mmol/l
0.10
194
1134
457
3613
2.43
15.20
4.9
4.1
14.49
14.56
pmol/l
0.24
425
3311
161
905
2.09
13.03
1.8
1.5
18.78
19.76
nmol/l
0.45
144
799
287
1974
1.93
13.00
8.1
9.2
1.22
1.21
mmol/l
0.83
256
1738
227
1445
1.96
12.94
2.0
1.7
98.55
98.49
pmol/l
0.01
124
757
157
899
2.04
11.95
3.2
2.7
—
—
—
0
0
234
1550
1.87
11.49
5.0
6.4
38.15
37.75
g/l
0.51
220
1473
102
503
2.26
11.36
3.0
2.5
—
—
—
0
0
281
1981
1.84
11.22
3.0
3.0
69.53
69.53
nmol/l
0.00
269
1861
230
1524
1.86
11.21
3.7
3.5
26.98
31.86
u/l
3.17
219
1451
451
3708
2.10
11.10
4.5
3.4
5.60
5.60
mmol/l
0.02
427
3435
505
4360
2.59
10.82
17.1
13.1
3.92
3.92
mmol/l
0.01
499
4226
489
4163
2.36
10.81
6.2
4.8
1.85
1.83
mu/l
0.17
469
3929
386
3030
1.88
10.61
7.9
6.9
87.36
86.70
u/l
0.08
369
2873
350
2671
1.83
10.48
9.4
8.9
0.18
0.19
e9/l
0.37
310
2332
161
981
1.90
9.99
3.1
2.3
166.07
392.21
u/l
1.86
152
936
269
1924
1.76
9.80
6.9
6.4
11.02
12.01
umol/l
0.45
258
1810
109
584
2.08
9.76
1.6
1.6
440.59
13086382.79
pmol/l
0.50
94
512
256
1811
1.76
9.64
7.4
9.4
1.22
1.22
mmol/l
0.21
244
1698
338
2590
1.77
9.59
8.6
8.4
0.55
0.55
e9/l
0.24
292
2221
338
2591
1.77
9.57
8.6
8.4
0.04
0.04
e9/l
0.03
292
2220
181
1158
1.83
9.57
2.7
2.7
52.45
60.63
u/l
0.93
170
1079
346
2687
1.75
9.19
8.6
8.3
2.02
2.07
e9/l
0.60
305
2367
330
2544
1.72
8.86
8.7
8.4
32.31
31.79
%
0.38
318
2454
319
2437
1.72
8.85
8.8
8.6
8.69
8.48
%
0.73
305
2327
171
1106
1.79
8.56
2.9
3.2
1.02
1.02
kg/l
0.02
104
687
316
2432
1.69
8.31
8.8
8.5
2.91
2.91
%
0.01
300
2319
83
425
2.12
8.31
1.6
1.6
1097.99
1120.63
nmol/l
0.09
68
331
195
1323
1.73
8.20
3.8
3.9
8.70
8.85
mmol/l
0.12
172
1190
103
576
1.97
8.10
2.3
2.0
—
—
—
0
0
66
313
2.26
7.99
2.2
1.6
0.17
0.24
mg/l
0.89
26
136
112
649
1.91
7.92
6.6
8.0
0.85
0.81
mmol/l
1.21
106
615
355
2842
1.68
7.82
12.4
10.9
3.69
3.85
e9/l
0.77
308
2439
313
2427
1.66
7.80
8.9
8.6
0.66
0.65
%
0.04
299
2313
115
676
1.88
7.77
2.3
1.9
—
—
—
0
0
119
719
1.83
7.35
2.3
1.9
—
—
—
0
0
67
331
2.16
7.34
1.9
2.1
0.00
0.00
estimate
-0.00
15
89
119
726
1.81
7.10
2.3
1.9
—
—
—
0
0
118
722
1.80
6.96
2.3
1.9
—
—
—
0
0
385
3194
1.65
6.95
4.4
3.4
30.77
34.10
u/l
0.98
366
3077
316
2500
1.60
6.91
8.8
8.3
52.77
53.79
%
0.79
308
2418
174
1196
1.66
6.74
2.8
2.6
2.57
2.61
mg/l
0.10
152
1043
240
1795
1.59
6.55
8.5
8.6
—
—
—
0
0
318
2540
1.58
6.52
3.6
3.4
74.90
71.49
ug/l
0.19
301
2405
161
1100
1.65
6.32
3.7
2.9
27.07
36.09
ng/l
0.28
85
552
114
720
1.73
5.98
2.0
1.9
—
—
—
0
0
229
1722
1.56
5.95
1.6
1.7
0.79
2.49
u/ml
2.81
56
401
343
2821
1.56
5.93
4.8
4.1
6211.20
526.85
e6/l
—
5
33
134
889
1.67
5.85
5.2
4.5
—
—
—
0
0
169
1190
1.60
5.81
3.3
3.6
0.00
0.00
estimate
0.50
61
457
303
2443
1.52
5.61
5.2
6.0
6.19
6.35
mmol/l
0.71
279
2240
9
7
13.04
5.59
1.7
3.9
—
—
—
0
0
95
589
1.74
5.29
2.6
2.6
2.41
2.42
mmol/l
0.66
90
513
41
190
2.25
5.27
1.7
2.3
10.21
5.81
iu/ml
—
7
33
58
308
1.98
5.25
3.6
4.8
77.12
68.28
e9/l
0.53
39
191
189
1402
1.52
5.05
3.6
3.8
27.13
38.70
e6/l
0.37
147
1026
152
1075
1.57
5.03
3.7
4.1
7.39
7.39
ph
0.17
106
744
291
2361
1.48
5.00
3.9
3.6
0.05
0.00
estimate
0.49
60
461
251
1979
1.49
4.97
3.2
3.3
6.28
6.26
ph
0.10
128
1032
26
100
2.68
4.96
1.2
1.1
—
—
—
0
0
123
835
1.61
4.83
2.9
3.0
554.37
576.80
mosm/kgh2o
0.40
105
728
50
262
2.00
4.71
6.3
4.0
7.34
7.31
ph
0.30
43
202
20
69
2.97
4.65
1.6
2.2
—
—
—
0
0
287
2350
1.45
4.55
3.7
3.6
0.00
3.42
estimate
0.50
63
475
28
117
2.47
4.55
1.3
2.7
—
—
—
0
0
100
654
1.64
4.55
1.5
1.5
300.00
415.00
titre
1.30
16
120
181
1356
1.49
4.53
6.0
7.7
1.12
1.13
inr
0.15
155
1116
292
2401
1.45
4.51
12.7
11.3
0.00
0.00
e9/l
0.35
237
1909
97
631
1.65
4.50
2.8
2.8
14.74
14.17
umol/l
0.29
91
596
72
432
1.76
4.48
1.6
1.4
288.96
482.90
u/ml
0.44
65
399
284
2328
1.45
4.43
3.7
3.5
0.00
0.00
estimate
-0.00
64
487
38
184
2.14
4.42
1.7
2.1
0.00
0.00
estimate
-0.00
14
72
84
529
1.69
4.41
4.1
4.5
7.82
7.29
umol/l
0.06
71
443
513
4769
1.88
4.34
12.6
9.7
27.73
27.37
u/l
0.16
504
4652
399
3497
1.49
4.32
4.9
4.5
36.37
36.92
mmol/mol
0.59
383
3343
23
93
2.54
4.01
1.1
1.1
—
—
—
0
0
166
1252
1.46
3.93
3.6
3.7
0.40
0.24
e6/l
0.48
124
884
130
934
1.51
3.91
2.4
3.1
9.34
6.65
e6/l
0.85
113
831
433
3889
1.50
3.89
4.1
3.7
1.37
1.40
mmol/l
0.92
414
3695
70
435
1.70
3.86
2.4
3.5
10.38
9.93
g/l
0.58
64
407
436
3928
1.49
3.79
4.5
4.0
2.68
2.74
mmol/l
0.72
419
3727
57
336
1.78
3.78
2.3
2.3
11.91
14.42
au/ml
—
7
33
406
3615
1.45
3.69
3.7
3.3
1.19
1.20
mmol/l
0.11
385
3419
195
1531
1.42
3.68
9.1
7.5
—
—
—
0
0
434
3916
1.48
3.66
4.3
3.8
4.43
4.55
mmol/l
1.66
417
3738
95
648
1.56
3.61
1.3
1.3
—
—
—
0
0
104
724
1.54
3.61
1.4
1.3
17.35
23.27
iu/ml
0.33
19
191
71
452
1.65
3.58
2.3
2.4
162.82
30.70
u/l
0.52
60
374
88
593
1.57
3.53
2.6
2.8
2.49
2.46
g/l
0.26
83
555
62
385
1.69
3.44
6.7
11.5
1.50
1.44
mmol/l
0.10
62
372
12
32
3.81
3.40
1.3
2.4
10.44
15.91
umol/l
1.27
12
32
13
42
3.14
3.39
1.2
1.1
—
—
—
0
0
126
925
1.47
3.38
3.5
2.8
1.07
1.15
mg/l
0.12
82
651
24
111
2.21
3.17
1.6
1.4
242.91
337.33
ug/g
1.23
11
64
148
1133
1.42
3.15
4.7
5.3
—
—
—
0
0
18
75
2.45
3.00
1.8
3.7
—
—
—
0
0
209
1709
1.36
2.96
3.3
3.2
0.10
0.00
estimate
0.72
51
413
69
459
1.57
2.93
1.2
1.3
144.36
135.01
u/ml
0.07
23
150
173
1378
1.37
2.89
1.8
1.8
—
—
—
0
0
192
1558
1.35
2.84
1.7
1.6
1.83
1.98
g/l
0.84
117
894
209
1719
1.34
2.82
4.6
4.5
18.68
48.89
e6/l
2.62
154
1102
547
5286
2.39
2.80
25.5
18.3
88.34
88.45
fl
0.21
541
5243
547
5288
2.38
2.76
25.5
18.3
29.58
29.69
pg
0.75
541
5244
547
5288
2.38
2.76
25.5
18.4
4.66
4.64
e12/l
0.28
530
5151
547
5288
2.38
2.76
26.0
19.0
40.71
42.31
%
0.85
541
5241
547
5289
2.37
2.74
25.6
18.4
6.68
6.69
e9/l
0.03
529
5150
101
740
1.44
2.72
3.8
3.5
1.73
2.93
e6/l
1.44
58
352
80
561
1.50
2.69
2.2
1.7
—
—
—
0
0
547
5292
2.35
2.68
25.7
18.6
136.96
137.23
g/l
0.17
541
5247
51
323
1.64
2.66
6.7
5.1
0.47
0.62
%
0.28
17
93
35
584
0.57
2.66
1.3
1.2
—
—
—
0
0
546
5282
2.26
2.61
25.6
18.4
261.68
259.84
e9/l
0.28
531
5158
8
20
4.04
2.57
1.6
1.1
—
—
—
0
0
34
194
1.80
2.57
2.2
2.3
5.92
8.59
ug/l
0.28
28
169
17
77
2.25
2.39
2.3
3.9
193.18
204.31
e6/l
0.10
11
55
28
154
1.86
2.38
2.1
2.4
—
—
—
0
0
25
133
1.92
2.35
1.7
3.3
—
—
—
0
0
497
4713
1.48
2.28
16.8
12.2
19.31
22.27
mg/l
1.66
385
3606
56
380
1.53
2.21
1.6
1.5
—
—
—
0
0
51
339
1.55
2.21
7.4
5.3
0.88
0.81
%
0.08
16
101
103
1322
0.73
2.21
1.8
1.8
—
—
—
0
0
53
357
1.54
2.17
2.4
2.0
—
—
—
0
0
49
327
1.55
2.09
7.6
5.3
0.21
0.09
%
0.48
14
86
88
660
1.40
2.09
3.4
3.3
232.51
829.37
ng/l
1.45
37
371
17
82
2.11
2.09
2.2
3.9
1114.27
1493.80
e6/l
1.41
11
59
89
670
1.39
2.07
1.4
1.3
8.09
7.18
u/ml
0.06
36
269
10
38
2.66
2.01
1.1
1.1
258.50
290.12
mg/l
—
10
33
16
77
2.11
1.98
2.2
3.8
474.70
570.31
e6/l
—
10
52
66
475
1.44
1.97
3.9
2.5
2493.67
6721.00
u/l
1.33
25
196
64
458
1.45
1.97
1.4
1.3
—
—
—
0
0
18
91
2.01
1.97
2.2
4.2
—
—
—
0
0
49
333
1.52
1.94
8.2
5.6
0.00
0.09
%
1.29
14
79
120
960
1.32
1.89
3.2
3.1
146.10
116.93
ug/g
0.44
96
768
43
286
1.55
1.88
1.1
1.2
4.69
6.50
u/ml
0.53
31
210
46
311
1.52
1.87
1.2
1.2
2.48
3.13
u/ml
0.19
33
211
89
682
1.36
1.86
7.9
9.9
1.14
1.19
mmol/l
0.76
84
641
48
329
1.50
1.84
1.4
1.3
170.50
255.04
miu/ml
1.05
18
169
8
29
2.78
1.79
1.0
1.8
—
—
—
0
0
132
1078
1.29
1.78
2.8
2.6
—
—
—
0
0
504
4838
1.41
1.69
13.3
9.5
—
—
—
0
0
38
253
1.54
1.68
1.4
1.3
—
—
—
0
0
12
238
0.49
1.67
1.1
1.1
0.84
0.87
g/l
0.21
12
238
5
14
3.59
1.62
1.0
1.1
—
23.38
—
0
5
12
235
0.50
1.61
1.0
1.1
1.64
1.48
g/l
0.73
12
235
14
70
2.03
1.60
1.3
1.2
—
—
—
0
0
25
152
1.67
1.59
1.7
1.7
—
—
—
0
0
80
619
1.34
1.59
5.8
9.0
1.71
1.37
mmol/l
0.59
68
505
65
488
1.38
1.56
5.6
7.9
7.41
7.41
ph
0.03
49
404
5
15
3.35
1.52
1.0
1.8
148.13
144.00
mmol/24h
—
5
15
14
72
1.97
1.50
2.0
4.2
13.07
9.18
%
0.86
14
72
5
16
3.14
1.44
2.0
2.2
—
—
—
0
0
5
16
3.14
1.44
1.0
1.1
141.60
137.44
nmol/l
—
5
16
40
281
1.46
1.40
1.1
1.2
1.17
1.28
u/ml
0.06
26
176
457
4353
1.27
1.40
21.3
15.8
13.19
13.17
%
0.12
452
4306
29
191
1.55
1.37
3.2
4.4
6.08
6.85
ug/l
0.08
23
149
182
1587
1.22
1.37
2.1
1.9
1.37
1.36
mmol/l
0.06
151
1419
6
23
2.63
1.37
1.2
1.2
—
—
—
0
0
64
491
1.34
1.36
2.0
1.5
—
—
—
0
0
155
1333
1.22
1.33
3.2
2.8
0.02
0.00
estimate
0.41
51
397
32
218
1.50
1.31
1.4
1.4
—
—
—
0
0
9
43
2.11
1.30
1.6
1.2
—
—
—
0
0
42
303
1.42
1.29
1.1
1.1
—
—
—
0
0
35
244
1.46
1.29
3.8
4.8
1.22
1.23
mmol/l
0.63
28
214
5
18
2.79
1.28
1.8
4.7
136.00
176.39
ug/l
—
5
18
39
280
1.42
1.24
1.1
1.2
2.81
2.69
u/ml
0.03
29
192
78
625
1.29
1.24
6.0
9.0
7.38
7.37
ph
1.12
47
406
5
19
2.65
1.22
1.0
1.0
—
—
—
0
0
13
71
1.85
1.20
3.5
4.9
9.08
14.17
%
0.86
13
71
95
785
1.25
1.18
4.3
4.6
11.52
11.26
mg/mmol
0.01
61
540
41
301
1.39
1.16
1.1
1.2
—
—
—
0
0
60
468
1.32
1.16
7.8
10.0
105.68
104.54
mmol/l
1.19
60
468
0
34
0.00
1.16
0.0
2.7
—
2.61
—
0
34
34
242
1.43
1.14
1.3
1.8
321.20
192.64
u/ml
1.00
15
135
14
80
1.77
1.14
3.1
5.8
3.90
2.35
mmol/l
—
7
44
207
1855
1.18
1.13
2.8
2.4
—
—
—
0
0
10
51
1.98
1.12
1.3
1.8
7.04
4.63
mmol/24h
—
10
46
28
193
1.47
1.11
4.3
8.9
0.61
0.59
%
0.11
28
193
35
253
1.41
1.09
1.4
1.6
—
—
—
0
0
27
186
1.47
1.08
1.6
1.7
4.90
5.48
u/ml
—
5
50
12
67
1.81
1.05
1.3
1.2
2.76
4.34
u/ml
—
6
55
5
22
2.28
1.03
2.0
1.5
73.60
69.82
umol/l
—
5
22
41
537
0.74
1.03
1.6
1.5
3.43
3.34
mmol/l
0.24
28
347
7
34
2.07
1.03
2.4
2.9
692.29
965.47
u/ml
—
7
34
22
147
1.52
1.02
2.1
2.3
2.79
4.59
iu/l
—
9
67
41
309
1.35
1.02
3.1
2.0
6.28
6.34
ph
0.20
27
188
7
35
2.01
1.00
1.9
1.5
—
—
—
0
0
120
1036
1.20
0.99
2.9
2.7
—
—
—
0
0
9
49
1.85
0.99
1.7
1.6
—
—
—
0
0
7
36
1.96
0.97
1.3
1.3
112.43
104.81
pmol/l
—
7
36
0
32
0.00
0.95
0.0
3.3
—
17.95
—
0
32
7
37
1.90
0.94
1.7
2.4
32.57
31.51
pg
—
7
37
7
37
1.90
0.94
1.7
1.2
—
—
—
0
0
149
1320
1.18
0.92
3.0
2.7
—
—
—
0
0
92
780
1.21
0.92
3.8
3.9
56.59
64.16
mg/l
0.15
61
548
6
28
2.15
0.91
1.2
1.1
—
—
—
0
0
66
541
1.25
0.90
2.6
2.1
—
—
—
0
0
6
29
2.08
0.89
1.0
1.0
—
—
—
0
0
14
87
1.62
0.88
1.9
4.4
—
—
—
0
0
11
64
1.73
0.86
2.1
5.7
5.45
8.03
pmol/l
0.90
11
64
8
44
1.83
0.86
3.6
3.4
0.75
0.75
index
—
8
44
51
409
1.27
0.84
6.5
8.0
—
—
—
0
0
69
574
1.23
0.84
8.2
11.0
—
—
—
0
0
11
65
1.71
0.83
2.2
4.2
31.55
26.98
%
0.60
11
65
6
33
1.83
0.79
1.3
1.2
338.00
195.36
iu/ml
—
6
33
48
589
0.80
0.77
1.5
1.6
1119.97
987.29
mu/l
0.46
43
523
23
166
1.40
0.77
10.3
15.2
17.07
16.25
%
0.97
23
155
9
55
1.65
0.73
1.7
1.8
5.56
2.52
u/ml
—
9
55
7
41
1.72
0.70
1.0
1.1
—
—
—
0
0
60
503
1.22
0.70
1.6
1.4
—
—
—
0
0
12
77
1.57
0.69
2.5
3.9
39.84
39.16
%
0.07
12
77
7
42
1.67
0.68
1.4
1.1
—
—
—
0
0
26
197
1.34
0.67
5.0
3.8
86.94
142.56
ng/l
0.96
18
176
12
78
1.55
0.66
1.8
1.7
0.51
0.51
e9/l
0.02
12
78
39
314
1.26
0.65
8.6
11.5
7.40
7.42
ph
0.63
21
152
7
44
1.60
0.65
1.0
1.2
—
—
nmol/l
—
0
0
20
146
1.38
0.64
1.5
1.5
—
76.50
—
0
20
25
191
1.32
0.62
1.0
1.1
7.02
10.61
u/ml
0.26
15
113
5
30
1.67
0.61
2.4
4.3
—
—
—
0
0
27
209
1.31
0.61
1.0
1.1
7.29
6.63
u/ml
0.06
17
132
8
50
1.61
0.61
1.0
1.2
—
—
—
0
0
8
51
1.58
0.60
1.4
1.2
—
—
—
0
0
8
52
1.55
0.59
1.0
1.2
—
—
—
0
0
6
37
1.63
0.55
1.2
1.0
2561.83
1355.38
miu/ml
—
6
37
6
37
1.63
0.55
1.0
1.1
—
—
—
0
0
61
527
1.18
0.54
3.2
2.9
4.00
5.00
e9/l
0.76
56
479
6
40
1.51
0.51
1.2
3.0
—
—
—
0
0
43
362
1.20
0.51
1.8
2.0
14.03
13.30
iu/l
0.07
29
267
9
65
1.39
0.50
6.7
19.4
11.28
11.96
%
—
9
65
21
162
1.31
0.50
1.6
1.3
—
—
—
0
0
7
45
1.56
0.49
1.9
1.1
—
—
—
0
0
201
1893
1.10
0.46
3.2
3.0
—
—
estimate
—
0
0
37
311
1.20
0.46
8.9
11.5
0.72
0.64
mmol/l
0.05
29
255
24
192
1.26
0.45
12.1
13.1
24.42
24.22
mmol/l
0.17
24
187
58
508
1.16
0.45
2.2
2.4
12.91
12.77
nmol/l
0.03
48
477
7
50
1.40
0.45
1.0
1.2
21.51
18.77
u/l
—
7
43
0
15
0.00
0.41
0.0
5.1
—
14.94
—
0
8
0
15
0.00
0.41
0.0
2.9
—
110.73
—
0
15
0
15
0.00
0.41
0.0
1.7
—
—
—
0
0
10
71
1.42
0.39
1.3
1.2
—
—
—
0
0
103
947
1.11
0.39
2.0
1.7
—
—
—
0
0
151
1415
1.09
0.39
2.0
1.8
—
—
—
0
0
21
169
1.25
0.39
1.0
1.2
—
—
—
0
0
18
142
1.28
0.39
1.2
1.5
0.41
0.34
nmol/l
0.20
13
116
67
602
1.13
0.38
3.9
3.5
1.56
1.46
ug/l
0.10
58
540
161
1707
0.92
0.37
2.5
2.4
—
—
—
0
0
9
69
1.31
0.37
1.0
1.1
—
—
—
0
0
17
134
1.28
0.37
4.2
2.7
2.10
3.97
index
—
10
84
5
77
0.65
0.36
1.6
2.0
—
—
—
0
0
48
425
1.14
0.34
1.2
1.2
—
—
—
0
0
49
435
1.14
0.34
1.7
1.8
—
—
—
0
0
23
191
1.21
0.34
1.8
1.9
—
—
—
0
0
6
47
1.28
0.32
1.0
2.0
117.17
118.84
ng/l
—
6
42
20
240
0.83
0.31
2.1
1.4
—
—
—
0
0
33
287
1.16
0.30
1.1
1.1
—
—
—
0
0
30
259
1.17
0.30
10.0
12.1
120.27
123.42
g/l
0.43
30
250
14
111
1.27
0.30
2.0
1.8
—
2506.67
—
0
6
17
139
1.23
0.29
1.1
1.2
—
—
—
0
0
7
57
1.23
0.29
1.0
1.0
—
—
—
0
0
20
167
1.20
0.29
1.3
1.2
—
—
—
0
0
8
63
1.27
0.28
3.0
2.3
—
—
—
0
0
67
616
1.10
0.27
1.7
1.6
—
—
—
0
0
20
168
1.20
0.27
1.2
1.2
—
—
—
0
0
25
215
1.17
0.27
1.0
1.1
—
—
—
0
0
22
190
1.16
0.23
1.0
1.1
0.19
1.50
u/ml
0.82
11
86
33
367
0.89
0.22
3.1
2.3
0.64
0.69
ug/l
0.18
19
167
21
182
1.16
0.21
1.9
1.9
93.45
105.47
au/ml
0.30
11
65
41
373
1.11
0.21
3.2
3.6
—
—
—
0
0
0
11
0.00
0.21
0.0
4.7
—
5.07
—
0
11
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.9
—
3.07
—
0
12
0
13
0.00
0.21
0.0
1.4
—
25.61
—
0
13
11
90
1.23
0.19
1.2
1.3
—
—
—
0
0
51
473
1.09
0.19
1.4
1.6
—
—
—
0
0
7
58
1.21
0.18
10.4
3.2
—
—
—
0
0
156
1614
0.95
0.18
1.6
1.7
—
—
—
0
0
14
162
0.86
0.16
1.6
2.1
220.21
219.90
pmol/l
0.00
14
156
16
140
1.15
0.15
1.5
1.5
—
—
—
0
0
11
93
1.19
0.14
1.8
1.9
8.17
4.04
ug/l
0.27
11
84
7
90
0.78
0.14
2.1
1.8
—
—
—
0
0
7
90
0.78
0.14
2.1
1.8
—
—
—
0
0
7
90
0.78
0.14
2.1
1.8
—
—
—
0
0
7
90
0.78
0.14
2.1
1.8
—
—
—
0
0
13
114
1.14
0.12
2.5
3.4
16.38
22.21
mu/l
0.40
13
107
18
199
0.90
0.11
5.6
6.9
256.82
317.79
mg/l
0.19
11
130
83
803
1.04
0.09
4.8
3.6
316.53
324.14
umol/l
0.29
78
737
12
107
1.12
0.08
16.6
10.8
—
—
—
0
0
14
128
1.10
0.06
3.6
7.2
—
—
—
0
0
9
101
0.89
0.06
1.3
1.2
—
—
—
0
0
13
141
0.92
0.05
5.4
5.1
24.46
24.65
mmol/l
0.10
13
132
15
141
1.07
0.03
3.9
9.5
24.41
24.41
mmol/l
0.00
15
129
124
1253
0.99
0.03
2.4
2.0
—
—
—
0
0
24
231
1.04
0.03
1.5
2.0
34.33
36.28
nmol/l
0.19
24
225
15
142
1.06
0.02
1.2
1.1
—
—
—
0
0
23
238
0.96
0.02
1.7
1.6
—
—
—
0
0
10
94
1.06
0.01
1.3
1.1
—
—
—
0
0
15
144
1.04
0.00
1.1
1.1
—
—
—
0
0
23
225
1.02
0.00
1.2
1.2
—
—
—
0
0
23
234
0.98
0.00
1.5
1.5
—
—
—
0
0
35
352
0.99
0.00
1.9
2.1
5.63
6.89
u/l
0.65
25
248
6
61
0.98
0.00
1.8
2.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
9.91
—
0
9
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
0.00
1.8
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
0.20
—
0
6
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.1
—
98.50
—
0
8
9
89
1.01
-0.00
1.1
1.5
22.29
15.80
u/l
—
9
78
0
5
0.00
-0.00
0.0
1.0
—
0.03
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.6
—
4.20
—
0
5
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.3
—
0.46
—
0
7
6
62
0.97
-0.00
5.0
5.3
2.11
1.93
ug/l
—
6
62
0
5
0.00
-0.00
0.0
1.2
—
195.20
—
0
5
0
7
0.00
-0.00
0.0
2.0
—
3.43
—
0
7

Mortality – FinRegistry

↥

Association

Association between endpoint KRA_PSY_TIC and mortality.

Females

Parameter HR [95% CI] p-value
KRA_PSY_TIC 1.34 [0.94, 1.92] 0.111
Birth year 0.994 [0.99, 1.0] 0.182

During the follow-up period (1.1.1998 — 31.12.2019), 63 out of 2389 females with KRA_PSY_TIC died.

Males

Parameter HR [95% CI] p-value
KRA_PSY_TIC 1.569 [1.19, 2.07] 0.001
Birth year 0.99 [0.98, 1.0] 0.03

During the follow-up period (1.1.1998 — 31.12.2019), 92 out of 6900 males with KRA_PSY_TIC died.

Mortality risk

Mortality risk for people of age

years, who have KRA_PSY_TIC.

N-year risk Females Males
1 0.136% 0.294%
5 0.77% 1.889%
10 1.82% 4.912%
15 3.571% 9.327%
20 6.152% 15.684%

Relationships between endpoints

↥

Index endpoint: KRA_PSY_TIC – Tic and related disorders

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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