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Use of rasagiline

PDMED_RASAGILINE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Medicine purchases: ATC N04BD02

1 out of 7 registries used, show all original rules.

836

4. Check minimum number of events

Min. number of events 3
836

5. Include endpoints

None

836

6. Filter based on genotype QC (FinnGen only)

836

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 836 380 456
Unadjusted period prevalence (%) 0.17 0.13 0.20
Median age at first event (years) 65.67 65.36 65.92

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
718
Matched controls
7179
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N87
ICPC
Parkinsonism
171.1
323.0
373
45
N04BA03
ATC
levodopa, decarboxylase inhibitor and COMT inhibitor; oral
414.3
323.0
432
26
193
Kela drug reimbursment
Rasagiline
9577.5
323.0
593
*
N04BC05
ATC
pramipexole; oral
48.7
323.0
489
301
110
Kela drug reimbursment
Parkinson's disease and comparable movement disrorders
7993.9
323.0
712
91
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
1078.7
323.0
683
127
N04BD01
ATC
selegiline; oral
498.2
323.0
514
36
G20
ICD-10 Finland
Parkinson disease
11145.1
323.0
714
106
N04BD02
ATC
rasagiline; oral
+∞
323.0
718
10
N04BC04
ATC
ropinirole; oral
282.8
323.0
350
24
N04BC09
ATC
rotigotine; transdermal
793.8
191.3
180
*
AAG20
NOMESCO Finland
Stereotactic intracranial implantation of electrodes
1421.8
126.0
119
*
N04BX02
ATC
entacapone; oral
211.5
121.7
123
7
N04BB01
ATC
amantadine; oral
41.9
104.7
131
38
F02.39*G20
ICD-10 Finland
Dementia in Parkinson's disease without information on additional symptoms
89.8
103.8
114
15
AEA50
NOMESCO Finland
Adjustment of implanted neurostimulator
263.2
91.8
92
*
N03AE01
ATC
clonazepam; systemic
11.6
89.6
178
198
N06DA03
ATC
rivastigmine; oral, transdermal
13.8
76.7
138
122
N04AA02
ATC
biperiden; systemic
31.8
69.2
92
33
R25.1
ICD-10 Finland
Tremor, unspecified
14.2
69.1
122
102
G04BD12
ATC
mirabegron; oral
5.7
67.3
223
522
N05AH04
ATC
quetiapine; oral
5.3
63.0
223
558
G25.9
ICD-10 Finland
Extrapyramidal and movement disorder, unspecified
29.9
54.2
73
27
AA1AD
NOMESCO Finland
CT of head and brain
3.6
50.5
306
1226
AEA00
NOMESCO Finland
Replacement of impulse generator of stimulation device in the nervous system
95.3
48.5
53
6
XA800
NOMESCO Finland
Neuropsychological investigation
9.5
48.1
103
124
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
3.1
41.6
324
1506
SPAT1215
SPAT
Assessment of need for medical rehabilitation
7.6
39.9
98
146
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
5.2
39.8
135
306
AA5EN
NOMESCO Finland
Brain reseptor or transprot protein distribution isotope imaging
74.1
37.4
42
6
C07AA05
ATC
propranolol; systemic
3.5
36.7
204
728
I95.1
ICD-10 Finland
Orthostatic hypotension
8.2
36.3
84
114
ZXM20
NOMESCO Finland
Intraoperative use of computerised tomography
33.4
36.2
47
15
SPAT1224
SPAT
Implementation of speech therapy rehabilitation plan
16.0
36.0
59
40
SPAT1229
SPAT
Assessment of need for aid
4.5
34.4
134
349
H02AA02
ATC
fludrocortisone; oral
33.4
33.9
44
14
N19
ICPC
Speech disorder
14.4
32.3
55
41
L28
ICPC
Limited function/disability (L)
3.2
31.8
196
746
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.6
30.9
116
289
A28
ICPC
Limited function/disability NOS
3.2
30.7
187
702
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.1
29.8
200
803
SPAT1216
SPAT
Assessment of functional ability
3.0
27.8
185
735
N06AX11
ATC
mirtazapine; oral
2.5
26.8
282
1471
N04BC06
ATC
cabergoline; oral (dopamine agonists)
35.6
26.7
34
10
F02.39
ICD-10 Finland
Dementia in Parkinson's disease without information on additional symptoms
60.3
25.2
29
5
R1250
NOMESCO Finland
Evaluation of functional capability
8.7
25.1
55
68
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
4.3
24.5
97
253
SPAT1231
SPAT
Assessment of adjustments needed in living environment
9.4
24.4
51
58
SPAT1234
SPAT
Support of social functional capacity
5.3
23.6
74
151
R35
ICD-10 Finland
Polyuria
4.0
23.6
101
283
G21.9
ICD-10 Finland
Secondary parkinsonism, unspecified
41.6
22.8
28
7
N04BC07
ATC
apomorphine; parenteral
+∞
22.0
21
*
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.8
21.9
165
697
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.7
21.6
178
791
N03AX12
ATC
gabapentin; oral
2.7
21.1
163
699
N04BC02
ATC
pergolide; oral
79.2
20.8
23
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.9
20.8
138
538
YX8AD
NOMESCO Finland
Stereotactic CT examination for dose design of radiotherapy
215.9
20.7
21
*
R53
ICD-10 Finland
Malaise and fatigue
2.5
20.5
185
864
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.2
20.4
266
1496
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
4.5
20.2
75
183
N04BX04
ATC
opicapone; oral
+∞
19.9
19
*
R4130
NOMESCO Finland
Speech therapy
7.3
19.8
48
70
M54.5
ICD-10 Finland
Low back pain
2.2
19.6
261
1471
U04
ICPC
Incontinence urine
4.5
19.1
69
164
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
4.1
19.0
78
209
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
6.1
19.0
52
90
M48.0
ICD-10 Finland
Spinal stenosis
2.7
18.9
140
582
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
3.7
18.8
87
259
R47.1
ICD-10 Finland
Dysarthria and anarthria
11.1
18.6
35
33
N05BA04
ATC
oxazepam; oral
2.3
18.5
211
1100
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
4.1
18.3
73
191
N06AB10
ATC
escitalopram; oral
2.6
17.3
146
650
XF606
NOMESCO Finland
Ortostatic test
12.6
16.0
28
23
SPAT1297
SPAT
Other function in accordance with speech therapy nomenclature
27.0
15.7
21
8
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.8
15.6
106
415
D21
ICPC
Swallowing problem
8.1
15.2
34
44
R60.0
ICD-10 Finland
Localized oedema
2.6
15.1
120
513
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
5.1
15.1
48
100
AAW01
NOMESCO Finland
Implantation of intracranial stimulation device
+∞
14.6
14
*
F02.30
ICD-10 Finland
Dementia in Parkinson's disease without additional symptoms
152.9
14.5
15
*
N28
ICPC
Limited function/disability (N)
7.2
14.3
34
49
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
3.5
14.2
68
208
A06AD11
ATC
lactulose; oral
2.4
14.1
133
624
K59.09
ICD-10 Finland
Constipation, unspecified
3.1
13.4
76
264
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
5.0
13.2
42
88
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
23.0
12.9
18
8
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
9.9
12.8
25
26
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
6.4
12.7
33
54
S01.0
ICD-10 Finland
Open wound of scalp
2.9
12.6
78
288
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.7
12.4
88
354
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.8
12.4
81
310
N29
ICPC
Neurological sympt/complt other
6.3
12.2
32
53
TAW99
NOMESCO Finland
Other minor neurosurgical procedure
16.2
12.2
19
12
G02CB01
ATC
bromocriptine; systemic
9.5
12.1
24
26
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.3
11.9
114
538
M41.9
ICD-10 Finland
Scoliosis, unspecified
9.9
11.8
23
24
JDB10
NOMESCO Finland
Percutaneous gastrostomy
7.9
11.7
26
34
XKD00
NOMESCO Finland
Uroflowmetry
2.0
11.6
163
909
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.7
11.5
81
322
R1260
NOMESCO Finland
Evaluation of communicative skills
5.7
11.4
32
58
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.1
11.4
136
705
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.1
11.4
138
722
W19
ICD-10 Finland
Unspecified fall
2.6
11.4
87
363
N31.8
ICD-10 Finland
Other neuromuscular dysfunction of bladder
14.2
11.0
18
13
WX290
NOMESCO Finland
Other blockade of nerve
1.8
10.8
267
1807
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.5
10.8
90
396
N02BE01
ATC
paracetamol; systemic, rectal
2.1
10.7
627
5524
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.9
10.7
67
250
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.8
10.6
67
251
KCV12
NOMESCO Finland
Urinary bladder endoscopic botulin therapy
8.7
10.6
22
26
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
4.2
10.6
39
96
JX1LA
NOMESCO Finland
Kinetic X-ray of alimentary tract with pictures
+∞
10.4
10
*
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
8.4
10.4
22
27
XKD06
NOMESCO Finland
Physiologic investigation of micturition
3.8
10.4
43
118
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
4.0
10.4
41
108
G04BD09
ATC
trospium; oral
4.4
10.2
36
85
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.6
10.2
74
301
L03
ICPC
Low back symptom/complaint
1.9
9.9
179
1087
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
3.4
9.8
47
146
SPAT1245
SPAT
Provision of support and information to patient’s family members
3.2
9.5
49
161
N04BC01
ATC
bromocriptine; oral
+∞
9.4
9
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.2
9.1
100
498
WX110
NOMESCO Finland
Local anesthesy
1.6
9.1
466
3805
H50.52
ICD-10 Finland
Exophoria
10.2
9.1
17
17
S70.0
ICD-10 Finland
Contusion of hip
3.9
9.0
36
96
AA5QN
NOMESCO Finland
NA
37.2
9.0
11
*
R23
ICPC
Voice symptom/complaint
5.2
9.0
27
54
NF1AA
NOMESCO Finland
Hip X-ray examination
2.3
9.0
81
369
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
6.2
9.0
23
38
G23.9
ICD-10 Finland
Degenerative disease of basal ganglia, unspecified
18.9
9.0
13
7
N03AX16
ATC
pregabalin; oral
1.8
8.8
183
1161
S01.41
ICD-10 Finland
Open wound in the temple-jaw region
9.1
8.6
17
19
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
2.8
8.5
54
203
TKC22
NOMESCO Finland
Catheterisation instruction
4.5
8.5
29
67
R13
ICD-10 Finland
Dysphagia
2.5
8.5
67
285
S72.0
ICD-10 Finland
Fracture of neck of femur
3.4
8.5
39
118
K02.1
ICD-10 Finland
Caries of dentine
1.6
8.4
363
2809
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
5.6
8.3
23
42
N86
ICPC
Multiple sclerosis
14.7
8.2
13
9
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
4.9
8.1
25
52
M79.6
ICD-10 Finland
Pain in limb
1.6
8.1
255
1814
L17
ICPC
Foot/toe symptom/complaint
1.7
8.0
198
1316
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.4
7.9
64
277
A04
ICPC
Weakness/tiredness general
2.0
7.9
98
517
NAG63
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, more than 3 vertebraea
8.6
7.8
16
19
G90.3
ICD-10 Finland
Multi-system degeneration
45.5
7.7
9
*
M54.4
ICD-10 Finland
Lumbago with sciatica
1.9
7.7
122
704
SAA02
NOMESCO Finland
Basic examination of mouth
1.6
7.7
397
3179
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
10.2
7.6
14
14
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
7.2
7.5
17
24
XKC03
NOMESCO Finland
Water cystometry
3.2
7.5
37
119
S06.0
ICD-10 Finland
Concussion
2.3
7.5
71
332
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.5
7.4
340
2636
A03FA01
ATC
metoclopramide; systemic, rectal
0.5
7.4
49
977
AA1AA
NOMESCO Finland
Head X-ray examination
7.8
7.4
16
21
UKC02
NOMESCO Finland
Cystoscopy
1.8
7.4
144
889
M70.6
ICD-10 Finland
Trochanteric bursitis
2.0
7.3
98
532
N30.9
ICD-10 Finland
Cystitis, unspecified
2.7
7.3
47
179
G04BD08
ATC
solifenacin; oral
2.3
7.3
67
307
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.9
7.3
108
607
A06AC01
ATC
ispaghula (psylla seeds); oral
1.7
7.2
185
1236
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.4
7.2
62
277
SPAT1305
SPAT
Counselling and guidance related to physical exercise
2.2
7.2
74
359
NA1AD
NOMESCO Finland
Cervical spine CT examination
3.2
7.2
36
117
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
5.2
7.0
20
39
Z50.5
ICD-10 Finland
Speech therapy
5.9
6.9
18
31
R60.9
ICD-10 Finland
Oedema, unspecified
2.8
6.8
43
161
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.6
6.8
248
1814
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.5
6.8
359
2859
N06AX21
ATC
duloxetine; oral
2.1
6.7
73
363
N08
ICPC
Abnormal involuntary movements
22.7
6.7
9
*
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
3.1
6.5
34
115
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
0.3
6.5
14
439
M41.4
ICD-10 Finland
Neuromuscular scoliosis
70.4
6.4
7
*
R33
ICD-10 Finland
Retention of urine
2.1
6.4
71
357
AA1BD
NOMESCO Finland
Extensive CT of head and brain
3.2
6.4
31
99
N31.0
ICD-10 Finland
Uninhibited neuropathic bladder, not elsewhere classified
14.5
6.4
10
7
Z50.1
ICD-10 Finland
Other physical therapy
2.4
6.4
51
219
SPAT1254
SPAT
Administration of medicine
1.8
6.4
103
597
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.8
6.4
39
146
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.8
6.4
113
678
NAG66
NOMESCO Finland
Posterior interbody fusion of lumbar spine, 2 vertebrae
9.4
6.3
12
13
M20.4
ICD-10 Finland
Other hammer toe(s) (acquired)
2.7
6.3
41
159
F0230, G20
ICD-10 Finland
NA
+∞
6.3
6
*
N04BX01
ATC
tolcapone; oral
+∞
6.3
6
*
N87
ICD-10 Finland
Dysplasia of cervix uteri
+∞
6.3
6
*
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.6
6.2
181
1248
SPAT1172
SPAT
Guidance concerning hydration
3.8
6.1
24
65
SPAT1263
SPAT
Sampling
1.5
6.1
285
2192
N30.0
ICD-10 Finland
Acute cystitis
1.9
6.1
92
522
L75
ICPC
Fracture: femur
6.1
6.0
15
25

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
43
26
17.38
51.64
1.9
1.2
80.09
145.02
nmol/l
0.77
23
18
391
2342
2.26
28.75
4.8
3.3
—
—
—
0
0
382
2418
2.07
22.85
2.7
2.2
255.00
239.11
u/l
0.11
364
2266
638
4897
2.28
22.61
6.7
4.7
4.60
2305.17
e6/l
—
5
76
349
2200
2.01
20.52
3.4
3.4
0.47
0.49
e6/l
0.09
275
1690
534
3931
1.99
19.69
4.5
7.1
1.21
1.21
mmol/l
0.49
442
3327
587
4534
1.99
17.99
4.6
5.0
6.35
6.78
mmol/l
10.34
569
4279
397
2709
1.89
17.69
4.0
4.0
167.01
123.17
e6/l
0.35
299
1999
357
2384
1.87
16.76
3.7
3.5
187.44
93.33
e6/l
0.25
277
1874
625
5016
1.97
16.05
5.7
4.6
—
—
—
0
0
322
2105
1.86
15.99
3.5
3.3
—
—
—
0
0
475
3501
1.83
15.90
4.7
3.9
0.00
0.00
estimate
0.00
110
655
473
3509
1.80
15.22
6.5
5.3
0.00
0.00
estimate
0.00
111
663
477
3558
1.79
14.97
4.9
3.9
0.00
0.01
estimate
0.80
114
637
335
2261
1.80
14.69
3.7
4.5
—
—
—
0
0
254
1576
1.88
14.61
2.0
1.8
1162.76
1203.25
nmol/l
0.31
209
1171
300
1974
1.81
14.21
1.8
1.6
17.60
20.70
nmol/l
3.78
270
1652
480
3624
1.76
14.09
4.1
6.2
1.21
1.21
mmol/l
0.17
440
3267
448
3321
1.75
13.98
2.3
2.1
83.22
93.97
pmol/l
6.49
297
1709
456
3403
1.75
13.85
7.9
9.9
1.20
1.28
inr
1.59
151
927
415
3077
1.69
12.39
5.1
3.9
36.13
52.46
ng/l
0.73
346
2364
260
1698
1.77
12.29
1.8
1.7
388.55
15265919.09
pmol/l
1.32
222
1356
241
1549
1.78
11.98
3.4
3.0
595.85
551.02
mosm/kgh2o
2.60
220
1323
248
1654
1.71
10.62
2.7
2.7
5.58
4.58
e6/l
0.63
224
1468
117
621
2.03
10.38
5.9
4.1
—
—
—
0
0
333
2423
1.62
10.06
2.4
2.6
—
—
—
0
0
214
1392
1.72
9.95
3.0
2.9
1.39
1.06
e6/l
0.41
129
833
444
3504
1.57
9.25
3.8
4.1
—
—
—
0
0
34
107
3.27
8.99
2.3
3.0
—
—
—
0
0
261
1838
1.61
8.76
4.9
3.7
—
—
—
0
0
255
1793
1.61
8.59
1.3
1.3
—
—
—
0
0
170
2522
0.59
8.49
2.9
3.2
7.82
7.47
mmol/l
0.51
136
2071
369
2832
1.54
8.44
2.7
2.8
123.57
161.02
ug/l
3.15
322
2557
313
2342
1.54
7.91
2.6
4.2
7.40
7.40
ph
0.52
81
444
267
1932
1.56
7.83
2.4
2.1
3.09
3.10
mg/l
0.04
213
1626
171
2494
0.60
7.82
2.9
3.3
28.34
248.81
mg/l
2.75
118
1579
265
1935
1.54
7.38
5.2
4.2
0.00
0.00
estimate
0.50
107
627
112
661
1.80
7.15
3.1
3.8
1.23
1.22
mmol/l
0.10
97
573
370
2917
1.48
7.06
2.3
2.2
73.18
79.00
nmol/l
3.73
321
2543
759
7001
1.91
6.94
19.5
16.4
25.28
26.08
mg/l
0.29
661
5657
394
3168
1.46
6.67
11.1
10.2
0.00
0.00
e9/l
0.55
330
2600
186
1288
1.57
6.45
2.2
2.0
29.73
29.63
s
0.08
177
1243
188
1313
1.56
6.26
3.4
3.2
2.61
2.05
e6/l
0.28
104
756
193
2635
0.65
6.24
3.8
4.0
4.70
8.73
mg/mmol
1.88
130
1651
257
1941
1.47
5.85
3.6
4.1
86.57
86.86
%
0.07
252
1894
318
2505
1.43
5.77
4.3
5.8
—
—
—
0
0
145
2069
0.64
5.65
1.4
1.7
1.22
1.37
mmol/l
1.67
106
1702
426
3544
1.41
5.65
4.0
5.8
0.54
0.61
e9/l
7.50
363
3032
433
3617
1.41
5.58
4.2
5.9
2.26
1.89
e9/l
0.25
374
3160
427
3561
1.41
5.54
4.0
5.8
0.03
0.04
e9/l
6.81
363
3059
45
213
2.18
5.42
7.2
5.2
—
—
—
0
0
789
7465
2.01
5.30
22.4
19.4
140.00
139.68
mmol/l
3.36
772
7267
72
408
1.84
5.26
5.2
4.0
—
—
—
0
0
435
3674
1.38
5.06
4.3
6.0
0.17
0.20
e9/l
2.02
379
3215
243
1862
1.43
5.00
2.3
2.5
—
—
—
0
0
789
7484
1.96
4.96
22.4
19.6
3.96
3.99
mmol/l
4.55
771
7279
113
739
1.61
4.93
3.0
3.8
3.03
2.01
mmol/l
2.38
99
600
701
6457
1.53
4.86
4.8
4.7
1.92
2.20
mu/l
0.84
637
5773
389
3247
1.37
4.77
4.5
6.0
0.56
0.67
%
3.79
359
3024
590
5270
1.41
4.73
3.9
3.9
15.28
15.02
pmol/l
1.70
525
4687
36
165
2.23
4.72
4.3
4.1
2.54
2.46
mmol/l
0.06
29
112
222
1692
1.42
4.66
4.2
3.8
—
—
—
0
0
404
3402
1.36
4.64
4.6
6.2
24.07
26.65
%
4.51
368
3151
17
53
3.25
4.63
4.2
2.5
—
—
—
0
0
141
985
1.52
4.61
3.6
7.4
1.96
1.22
mmol/l
1.41
117
767
141
985
1.52
4.61
3.5
7.4
5.39
5.10
kpa
3.05
136
946
141
986
1.52
4.59
3.5
7.3
13.31
11.98
kpa
1.79
136
949
404
3408
1.36
4.56
3.6
5.0
35.21
34.96
g/l
0.42
372
3174
396
3335
1.36
4.50
4.4
6.0
2.71
2.88
%
0.78
366
3096
398
3356
1.35
4.48
4.5
6.0
61.46
57.94
%
6.85
368
3133
596
5357
1.39
4.43
3.6
4.3
10.99
13.56
mm/h
5.38
554
4888
766
7248
1.68
4.21
19.3
15.8
—
—
—
0
0
475
4142
1.34
4.15
5.8
9.3
4.26
4.16
e9/l
0.40
414
3626
394
3352
1.33
4.03
4.7
6.3
8.24
8.93
%
4.74
365
3125
89
581
1.60
3.93
3.7
4.3
—
—
—
0
0
312
2579
1.33
3.85
2.6
3.0
1042.71
1326.22
ng/l
1.32
269
2229
19
71
2.72
3.84
1.7
1.4
—
—
—
0
0
85
553
1.60
3.81
5.8
6.3
25.84
24.46
mmol/l
3.45
80
517
101
684
1.54
3.81
3.0
3.5
—
—
—
0
0
13
39
3.37
3.77
1.1
1.1
113.08
140.14
nmol/l
2.14
13
39
56
329
1.75
3.69
4.3
4.1
—
—
—
0
0
33
163
2.07
3.64
2.9
3.7
—
—
—
0
0
657
6989
0.72
3.57
3.8
4.8
1.44
1.45
mmol/l
0.06
576
6309
33
617
0.52
3.53
1.3
1.5
—
—
—
0
0
296
2452
1.32
3.53
5.1
4.2
—
—
—
0
0
200
1563
1.37
3.52
1.9
1.6
1.96
1.37
mg/l
0.94
162
1233
55
882
0.60
3.43
1.3
1.3
486.67
493.00
titre
0.01
12
200
18
70
2.61
3.40
1.6
1.1
—
—
—
0
0
17
65
2.65
3.32
1.4
1.2
360.92
383.67
nmol/l
0.20
12
55
123
895
1.44
3.27
1.7
1.7
—
—
—
0
0
683
7198
0.72
3.19
4.3
5.5
2.63
2.65
mmol/l
0.14
600
6516
89
614
1.50
3.10
1.6
2.7
—
—
—
0
0
666
7040
0.73
3.09
3.8
4.9
4.47
4.53
mmol/l
0.93
590
6406
122
902
1.41
2.98
3.8
7.6
96.70
95.48
%
3.63
117
871
53
327
1.66
2.97
1.7
1.9
—
—
—
0
0
100
713
1.46
2.97
1.4
3.1
65.32
66.36
g/l
0.79
84
644
623
5774
1.31
2.91
5.4
8.1
78.69
79.85
u/l
0.36
575
5402
11
289
0.37
2.89
1.1
1.3
—
—
—
0
0
637
6758
0.76
2.83
3.5
4.3
1.15
1.30
mmol/l
8.83
555
6051
35
595
0.57
2.75
1.2
1.6
—
—
—
0
0
10
260
0.38
2.59
1.4
1.4
—
—
—
0
0
23
114
2.05
2.58
1.3
1.4
—
—
—
0
0
165
1310
1.32
2.58
2.3
3.4
0.83
0.81
mmol/l
1.59
154
1228
6
178
0.33
2.56
2.2
1.2
—
87.27
—
0
11
111
831
1.39
2.53
3.8
4.6
—
—
—
0
0
646
6817
0.77
2.52
5.6
6.4
39.69
40.52
mmol/mol
1.71
573
6237
188
1528
1.30
2.47
2.7
3.2
2.46
2.46
mmol/l
0.03
166
1349
65
930
0.67
2.45
2.7
4.3
2.74
29.01
ug/l
2.17
47
776
7
191
0.36
2.43
2.0
1.2
—
555.00
—
0
6
304
2633
1.24
2.35
2.7
3.6
2.35
2.35
mmol/l
0.03
263
2279
793
7696
1.59
2.33
27.9
24.3
130.68
134.71
g/l
12.36
779
7556
39
614
0.62
2.30
1.2
1.5
—
—
—
0
0
72
509
1.45
2.27
3.5
3.0
—
—
—
0
0
144
1145
1.31
2.22
1.8
2.6
2.38
2.28
g/l
1.25
121
1065
792
7693
1.56
2.20
27.7
24.2
244.38
242.34
e9/l
0.42
773
7466
792
7694
1.56
2.19
27.6
24.1
30.31
30.46
pg
1.90
779
7556
792
7694
1.56
2.19
27.6
24.1
91.52
91.61
fl
0.26
779
7557
792
7695
1.56
2.18
27.7
24.2
4.35
4.45
e12/l
7.72
768
7442
37
228
1.65
2.15
1.2
1.5
285.80
273.07
ug/g
0.15
22
138
12
49
2.47
2.11
3.3
2.8
7.41
7.42
ph
—
6
15
47
311
1.54
2.05
2.0
2.2
240.14
512.90
ug/l
0.90
42
293
791
7695
1.52
2.02
27.7
24.2
6.78
6.75
e9/l
0.05
766
7446
30
178
1.71
2.01
2.3
2.6
16.09
15.87
%
0.08
14
97
51
727
0.68
1.91
1.2
1.4
—
—
—
0
0
6
156
0.38
1.90
1.2
1.2
—
—
—
0
0
95
731
1.34
1.86
1.8
2.2
171.59
133.09
ug/g
0.67
76
576
50
709
0.69
1.83
1.3
1.6
—
—
—
0
0
16
80
2.02
1.81
2.2
2.2
—
—
—
0
0
171
1427
1.25
1.80
3.2
4.8
—
—
—
0
0
23
386
0.58
1.79
1.1
1.4
—
—
—
0
0
601
5677
1.21
1.69
21.5
20.2
13.60
13.83
%
4.37
593
5550
141
1160
1.26
1.68
2.0
2.1
—
—
—
0
0
24
142
1.71
1.66
1.5
1.2
—
—
—
0
0
133
1089
1.26
1.65
2.0
2.6
20.11
22.76
%
1.33
107
924
5
132
0.38
1.63
1.0
1.4
—
—
—
0
0
114
921
1.28
1.59
1.4
1.4
—
—
—
0
0
53
719
0.72
1.54
1.5
1.5
—
—
—
0
0
40
570
0.69
1.53
1.2
1.5
—
—
—
0
0
10
205
0.48
1.52
1.2
1.4
—
—
—
0
0
272
2416
1.19
1.52
2.3
2.5
52.04
57.47
u/l
0.95
250
2216
149
1249
1.23
1.52
1.9
2.6
11.33
12.66
umol/l
1.55
129
1155
163
1380
1.23
1.51
1.2
1.2
1.29
1.32
u/ml
0.02
40
345
49
352
1.42
1.49
1.9
3.2
4.43
4.46
pmol/l
0.09
44
304
119
975
1.26
1.48
1.7
2.5
1.50
1.83
%
4.38
102
862
36
244
1.50
1.47
2.5
3.5
—
—
—
0
0
210
1835
1.19
1.40
4.1
7.0
—
—
—
0
0
5
124
0.40
1.37
1.2
1.5
—
—
—
0
0
28
183
1.55
1.36
2.0
2.2
—
—
—
0
0
643
6158
1.19
1.34
18.6
17.9
37.07
39.30
%
4.16
377
3940
0
39
0.00
1.34
0.0
2.8
—
977.42
—
0
31
264
2924
0.86
1.27
2.1
2.2
—
—
—
0
0
39
278
1.42
1.27
1.4
2.9
38.62
37.25
g/l
0.83
29
238
41
295
1.41
1.27
1.4
4.1
53.86
82.20
mg/l
0.64
31
241
44
321
1.39
1.26
1.5
2.9
8.56
10.71
g/l
4.83
34
276
41
296
1.40
1.25
1.4
4.1
25.58
43.93
mg/l
1.11
31
244
7
143
0.49
1.21
1.1
1.6
—
—
—
0
0
22
140
1.59
1.21
1.6
3.0
—
—
—
0
0
31
215
1.46
1.17
1.4
4.4
—
—
—
0
0
433
4048
1.14
1.17
4.0
6.6
10.69
11.77
umol/l
1.77
414
3830
0
33
0.00
1.16
0.0
2.7
—
4796.26
—
0
19
174
1521
1.18
1.16
4.0
4.1
47.89
325.28
ng/l
6.13
148
1271
179
1569
1.18
1.15
5.0
4.3
1.02
1.02
kg/l
0.12
33
230
41
549
0.73
1.14
5.3
2.8
9.18
10.97
g/l
2.07
36
500
10
51
1.97
1.11
1.2
1.1
—
—
—
0
0
69
553
1.27
1.07
3.1
4.5
5.67
0.66
%
0.40
15
152
10
52
1.93
1.06
3.5
1.8
—
—
—
0
0
23
336
0.68
1.06
1.3
1.4
—
—
—
0
0
90
748
1.23
1.03
2.2
2.6
60.43
70.48
e9/l
2.72
72
585
55
432
1.29
1.01
2.3
2.4
—
—
—
0
0
9
161
0.55
0.98
1.3
1.3
—
—
—
0
0
72
588
1.25
0.97
3.1
4.5
0.25
0.12
%
0.39
16
180
0
30
0.00
0.97
0.0
2.6
—
—
—
0
0
0
31
0.00
0.96
0.0
1.6
—
107.24
—
0
21
31
225
1.39
0.95
7.4
12.5
—
—
—
0
0
0
32
0.00
0.95
0.0
2.6
—
—
—
0
0
32
234
1.38
0.95
1.5
1.6
—
—
—
0
0
6
27
2.23
0.93
1.2
2.4
—
—
—
0
0
5
102
0.49
0.90
1.0
1.3
—
—
—
0
0
9
152
0.59
0.89
1.2
1.2
—
—
—
0
0
9
155
0.58
0.89
1.0
1.1
—
—
—
0
0
25
345
0.72
0.88
2.8
3.6
127.89
4208.39
u/ml
0.78
18
291
26
187
1.40
0.86
1.5
1.2
474.12
549.36
mg/l
0.81
26
174
553
5310
1.12
0.85
4.0
4.3
—
—
—
0
0
764
7500
1.22
0.85
8.8
11.6
15.54
25.87
u/l
106.89
695
7199
689
7057
0.87
0.84
4.4
5.1
5.95
6.05
mmol/l
1.65
602
6332
6
114
0.52
0.83
1.0
1.3
—
—
—
0
0
74
619
1.21
0.83
2.2
3.9
72.89
92.49
ng/l
1.94
59
536
8
46
1.75
0.82
1.1
1.8
—
—
—
0
0
8
47
1.71
0.81
3.1
2.3
—
—
—
0
0
0
24
0.00
0.79
0.0
1.0
—
—
—
0
0
6
33
1.82
0.79
2.5
1.1
—
—
—
0
0
0
26
0.00
0.78
0.0
1.7
—
—
—
0
0
9
53
1.71
0.75
1.7
1.2
—
—
—
0
0
14
207
0.67
0.73
1.1
1.1
—
—
—
0
0
6
108
0.55
0.72
2.7
2.7
—
—
—
0
0
15
216
0.69
0.69
1.1
1.2
—
—
—
0
0
102
1155
0.87
0.67
1.2
1.3
21.07
39.99
iu/ml
1.80
26
364
5
91
0.55
0.67
1.0
1.3
—
78.66
—
0
5
5
93
0.53
0.67
2.0
1.2
—
—
—
0
0
66
560
1.19
0.67
2.8
4.3
1.00
0.47
%
0.54
15
146
37
295
1.27
0.66
1.6
3.1
0.20
0.26
g/l
—
9
118
76
654
1.18
0.66
1.7
2.1
387.52
369.78
nmol/l
0.31
71
603
96
1089
0.87
0.65
1.2
1.3
5.09
14.60
u/ml
1.30
36
389
73
628
1.18
0.64
3.0
4.3
0.53
0.93
%
1.40
17
197
206
2221
0.90
0.61
3.1
3.2
—
—
—
0
0
0
20
0.00
0.60
0.0
1.3
—
23.31
—
0
13
0
20
0.00
0.60
0.0
1.4
—
—
—
0
0
0
21
0.00
0.60
0.0
1.9
—
28.59
—
0
14
43
356
1.22
0.57
1.7
1.9
1.55
2.14
ug/l
0.25
37
317
28
352
0.79
0.57
1.1
1.2
89.34
120.06
iu/ml
—
9
130
8
55
1.46
0.56
1.0
1.7
—
—
—
0
0
44
368
1.21
0.54
1.7
1.3
—
—
—
0
0
6
98
0.61
0.52
1.0
1.1
—
—
—
0
0
65
567
1.16
0.51
1.6
2.3
13.79
12.78
nmol/l
0.46
56
496
21
162
1.30
0.50
1.5
1.2
3.82
3.85
mmol/l
0.04
21
151
17
127
1.35
0.50
1.2
1.5
—
—
—
0
0
21
163
1.30
0.48
1.5
1.2
1.81
61.80
e6/l
0.96
16
126
86
769
1.13
0.48
2.6
2.5
6.83
7.04
ug/l
0.06
66
682
77
684
1.14
0.47
2.8
8.8
—
—
—
0
0
10
68
1.48
0.47
1.9
1.1
—
—
—
0
0
55
478
1.16
0.46
2.5
3.0
4.08
4.07
e9/l
0.01
34
339
55
479
1.16
0.45
1.2
1.2
—
—
—
0
0
15
113
1.33
0.43
1.1
1.1
—
—
—
0
0
5
32
1.57
0.42
1.0
1.5
80.48
57.51
ug/l
—
5
32
18
140
1.29
0.42
1.2
1.6
4.10
5.89
iu/l
—
5
43
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
1.36
—
0
10
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
3.3
—
—
—
0
0
0
16
0.00
0.41
0.0
7.9
—
—
—
0
0
0
17
0.00
0.40
0.0
5.9
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
1.73
—
0
10
12
88
1.37
0.40
2.3
3.0
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
2.85
—
0
9
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
0
19
0.00
0.39
0.0
7.1
—
—
—
0
0
194
2047
0.93
0.36
1.8
2.9
2080.46
8126.74
umol/l
2.20
156
1731
61
547
1.12
0.35
4.2
3.8
7.45
7.40
ph
—
10
76
77
702
1.11
0.34
2.5
2.5
32.37
41.82
u/l
0.43
65
592
84
770
1.10
0.33
2.1
2.2
0.20
0.20
g/l
0.06
75
716
7
53
1.32
0.31
4.0
1.6
—
—
—
0
0
43
383
1.13
0.29
2.0
3.9
26.41
24.24
mmol/l
2.65
37
348
114
1070
1.08
0.28
2.6
5.9
0.99
1.03
mmol/l
1.20
103
978
22
187
1.18
0.27
1.4
2.4
121.53
128.24
g/l
0.48
17
144
181
1891
0.95
0.26
3.2
3.2
0.63
0.77
ug/l
2.70
132
1330
25
217
1.16
0.24
1.3
1.2
—
—
—
0
0
9
77
1.17
0.24
1.6
1.3
—
—
—
0
0
18
153
1.18
0.22
1.6
2.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
53.55
—
0
11
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
173.20
—
0
5
0
10
0.00
0.21
0.0
1.2
—
1.78
—
0
10
0
10
0.00
0.21
0.0
1.1
—
875.68
—
0
5
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
3.3
—
—
—
0
0
29
324
0.89
0.20
1.3
1.2
—
—
—
0
0
222
2291
0.96
0.20
2.3
3.3
25.40
35.05
u/l
6.99
201
2169
330
3223
1.04
0.20
4.8
5.4
2.69
2.94
ug/l
0.22
297
2870
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
49
1.23
0.20
1.0
1.3
—
—
—
0
0
7
61
1.15
0.17
1.0
1.2
—
—
—
0
0
10
82
1.22
0.17
1.1
1.4
281.20
275.84
mosm/kgh2o
—
10
61
5
70
0.71
0.16
1.2
1.6
—
—
—
0
0
14
120
1.17
0.16
3.9
2.0
29.36
32.40
pg
1.29
14
120
19
168
1.13
0.15
4.8
3.7
27.86
27.06
mg/l
—
7
105
6
78
0.77
0.15
1.0
1.1
—
—
—
0
0
6
79
0.76
0.15
1.0
1.1
—
—
—
0
0
13
150
0.86
0.14
1.2
1.8
—
—
—
0
0
7
86
0.81
0.14
1.3
1.5
4.93
6.38
mmol/l
—
7
81
69
725
0.95
0.14
2.8
3.0
183.15
204.21
ng/l
0.24
62
667
554
5589
0.97
0.12
23.1
21.8
331.71
332.03
g/l
0.36
548
5556
23
212
1.09
0.10
1.1
1.1
—
—
—
0
0
5
45
1.11
0.10
14.8
14.7
—
—
—
0
0
16
176
0.91
0.09
2.2
1.7
—
—
—
0
0
20
184
1.09
0.09
1.8
2.8
8.26
7.82
kpa
0.86
20
165
11
97
1.14
0.09
1.5
4.2
—
—
—
0
0
6
56
1.07
0.08
2.2
3.1
—
—
—
0
0
5
64
0.78
0.08
2.2
2.2
—
—
—
0
0
14
154
0.91
0.08
1.9
2.1
64.18
60.53
%
0.27
14
154
8
77
1.04
0.07
1.1
1.2
—
—
—
0
0
7
81
0.86
0.07
1.0
1.3
—
—
—
0
0
9
85
1.06
0.07
1.0
1.5
—
—
—
0
0
9
87
1.03
0.07
1.4
1.3
—
—
nmol/l
—
0
0
9
87
1.03
0.07
1.4
1.3
—
—
—
0
0
8
91
0.88
0.06
2.0
1.3
31.01
31.89
iu/l
—
8
74
45
467
0.96
0.06
4.3
10.0
—
—
—
0
0
42
404
1.04
0.06
5.0
3.9
—
—
—
0
0
96
981
0.98
0.06
1.4
1.3
—
—
—
0
0
40
413
0.97
0.04
1.3
1.9
1.55
1.60
g/l
0.14
33
358
110
1114
0.99
0.03
15.0
27.2
1.10
1.30
inr
—
10
144
86
873
0.98
0.03
1.3
1.3
—
—
—
0
0
10
92
1.09
0.03
1.1
1.5
—
—
—
0
0
11
102
1.08
0.03
1.3
1.7
—
—
—
0
0
440
4414
0.99
0.02
2.9
3.3
44.47
55.22
u/l
0.73
399
4048
20
208
0.96
0.02
1.2
1.6
—
—
—
0
0
74
730
1.02
0.02
4.1
7.6
9.40
10.49
mmol/l
0.89
67
695
87
862
1.01
0.01
1.7
2.8
6.77
9.17
umol/l
0.78
73
760
38
387
0.98
0.01
2.3
2.8
—
—
—
0
0
46
453
1.02
0.01
1.2
1.3
—
—
—
0
0
20
194
1.03
0.00
1.4
2.8
—
—
—
0
0
12
116
1.03
0.00
1.8
2.8
—
—
—
0
0
13
126
1.03
0.00
2.2
2.6
—
—
—
0
0
21
213
0.99
0.00
1.2
1.7
5291.09
15425.52
e6/l
1.50
11
157
13
128
1.02
0.00
2.4
3.1
54.08
58.47
%
0.47
13
128
109
1088
1.00
0.00
1.2
1.2
—
—
—
0
0
12
121
0.99
0.00
2.3
2.8
3.67
4.39
e9/l
0.63
12
121
16
155
1.03
0.00
1.4
1.7
—
—
—
0
0
6
62
0.97
0.00
1.5
2.1
5.08
2.18
ug/l
—
6
50
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
6
66
0.91
0.00
1.2
1.0
242.33
309.89
ng/l
—
6
38
6
62
0.97
0.00
1.5
2.1
8.92
3.55
ug/l
—
6
53
0
7
0.00
0.00
0.0
3.1
—
—
—
0
0
125
1250
1.00
0.00
1.3
1.5
2.10
2.72
g/l
3.60
58
716
6
66
0.91
0.00
1.2
1.0
886.67
635.54
ng/l
—
6
37
0
5
0.00
0.00
0.0
1.0
—
0.06
—
0
5
0
6
0.00
0.00
0.0
3.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
330.60
—
0
5
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: PDMED_RASAGILINE – Use of rasagiline

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).